WEILL MEDICAL COLLEGE OF CORNELL UNIVERSITY
Infections with RSV are one of the major causes of viral lower respiratory tract illness. Protection against RSV may be achieved with an efficient vaccination strategy that induces neutralizing humoral immunity and a Th1-dominant cellular respo
Vaccination Against RSV with Capsid-modified Ad Vectors
The primary long-term goal of this ongoing project is to elucidate the nature of the underlying neural mechanisms responsible for the reinforcing and motivational properties of drugs of abuse. Previous work in this field has concentrated on coc
Mechanisms of opiate and stimulant drug reinforcement
Office of Research, Rm 3227 Cheadle Hall
Diseases, Disorders & Medical Disciplines
In response to NOT-OD-09-058 (NIH Announces the Availability of Recovery Act Funds for Competitive Revision Applications), the Norris Cotton Cancer Center (NCCC) requests CCSG developmental funds to promote cancer comparative effectiveness rese
Cancer Center Support Grant (CER Initiatives)
OFFICE OF SPONSORED PROJECTS 11 ROPE FERRY RD. #6210
This grant provided summer research experiences for two teachers, one graduate student, and two undergraduate students in health-related scientific research. Project NCE (no Cost Extension)ended 11/30/10.
GENETICS AND FUNCTIONAL STUDIES OF AGE-RELATED MACULAR DEGENERATION
Colleges, Universities, and Professional Schools
'Function and Regulation of the Human Splicing Factor SC35' was designed to study the role of SR proteins in regulated RNA processing, focusing on the following 3 specific aims: 1. Analyze the splicing program during heart development 2. Determ
FUNCTION AND REGULATION OF THE HUMAN SPLICING FACTOR SC35
Group B Streptococcus (GBS), the leading cause of invasive bacterial infections in human newborns, and a common cause of ascending placental infection triggering premature delivery or spontaneous abortion.  In studies published in Blood (2009),
SIALIC ACID O-ACETYLATION IN GBS PATHOGENESIS & IMMUNITY
Department of Housing and Urban Development
HOUSING AUTHORITY OF THE TOWN OF WINDSOR LOCKS
2009 Capital Fund Amendment to the Consolidated Annual Contributions Contract (ACC) for th American Recovery and Reinvestment Act (ARRA)
Assistant Secretary for Public and Indian Housing
For Grant Number 09-CH-36-59420. The stimulus monies are to be used for new construction of approximately 14 Single Family, Scattered Site Homebuyer Units for Low-Income, Native Families.  The intent is to assist the community members in obtain
Seneca Nation Housing Authority Competitive Stimulus Homebuyher Program
Housing Development, Construction & Management
Schizophrenia biomarkers discerned by cellular networks in DiGeorge syndrome. To understand the causes of schizophrenia we should ultimately consider its genetic underpinnings and developmental course (i.e. from the prenatal period though adult
SCHIZOPHRENIA BIOMARKERS DISCERNED BY CELLULAR NETWORKS IN DIGEORGE SYNDROME
The elongation of transcripts by RNA polymerase II is a complex process dependent upon nucleotide substrate levels, elongation factors, and co-transcriptional events such as splicing. Mutations in genes encoding elongation factor SI I (TFIIS),
RNA POLYMERASE II ELONGATION COMPLEX: STRUCTURE-FUNCTION
Even though major advances have been made in the past decade with respect to understanding the genetics, environmental and immune dysregulation in IBD, the etiopathogenesis of IBD is poorly understood. It is envisaged that this investigation wi
PREDOCTORAL TRAINING PROGRAM IN GENETICS Opportunities in the fields of genetics and molecular biology in academia, government, and in the private sector have increased with the explosion of genetic information and the potential to use this inf
PREDOCTORAL TRAINING PROGRAM IN GENETICS
Biochemistry, Biophysics & Molecular Biology
Efficacy and Mechanisms of GLN Dipeptide in the SICU (GLND trial): The purpose of this supplement is to accelerate the tempo of research in the current NIH/NIDDK-funded trial U01 DK069322 (the GLND study) by adding an additional study site at t
EFFICACY AND MECHANISM OF GLN DEPEPTIDE IN THE SIC
Endocrine, Metabolic & Nutritional Research
The goal of this proposal is to train talented students from underrepresented groups to become field ecologists engaging in international collaboration.  To accomplish this goal, the PIs will provide a comprehensive year-round research experien
US-Costa Rica Tropical Ecology Mentorship Program of Southern California:  Diversification and International Training of Undergraduates in Field Ecology
NORTHWEST TENNESSEE DEVELOPMENT DISTRICT INC
accessibility modification to Pawlet Town Hall
Pawlet Town Hall Accessibility Modification
Traffic Management Center Auxiliary Power Facility
Highway, Street, and Bridge Construction
AUTORIDAD DE CARRETERAS Y TRANSPORTACION
Highway Infrastructure Investment consisting in Bridge Replacement # 763, PR-2 km. 127.4 (PR-2 Access), Aguadilla.  This project is consider as a Bridge Replacement, no added capacity.
Bridge Replacement #763 PR-2 (PR-2 Access), km. 127.4, Aguadilla
José de Diego Ave., Centro Gubernamental Minillas
TRANSPORTATION, WASHINGTON STATE DEPARTMENT OF
Highway Infrastructure Investment Grant: Available for Use in Any Area (flexible)
SR 2/Monroe City Limit to Sultan - Overlay
EAGLES LANDING PKWY FROM CR 2417 TO CS 867/TALON PLACE-GRTA
Rt 52 Causeway Replace & Somers Pt Circle Elim Cont B
SR 8 / Elma to SR101 - Install Cable Median Crossover Barrier
LOCUST GROVE DOWNTOWN STREETSCAPE - PHASE II
SR 2/BATTLEFIELD PARKWAY AT CR 6/PINE GROVE ROAD
SR 42 AT 5 LOCS - UPGRADE TRAFFIC SIGNALS
SR 74 FROM SR 85 TO CS 597/COOPER CIRCLE
Highway Infrastructure Investment Grant: Available for Use in Any Area (Flexible)
Resurfacing Various Locations in Northern Anne Arundel County
Highway Infrastructure Investment Grant: Transportation Enhancements and Available for Use in Any Area (Flexible)
Resurfacing Various Locations in Montgomery County (Gaitherburg Shop)
Resurfacing Various Locations in Montgomery County (Fairland Shop)
Resurfacing Various Locations in Howard County
Traffic Detection in Districts 1,2,4, and 5
Highway Infrastructure Investment Grant:  Available for Use in Any Area (Flexible)
Resurfacing Various Locations in Garrett County
Upgrade and Replace Guardrail in Various Locations in Montgomery County
Safety and Resurfacing Various Locations in Wicomico County
Electrical Contractors and Other Wiring Installation Contractors
STATEWIDE PAVEMENT PRESERVATION (CRACK SEALING)
TRANSPORTATION, NORTH CAROLINA DEPARTMENT OF
SR 14/Cliffs Rd to Chamberlain/Goodnoe Rd - Chip Seal
ADAMS - RESURFACING AND RELATED WORK ON A SECTION OF ROUTE 116     The project will begin at the Adams/Cheshire town boundary (MM 66.3) and will end just north of Commonwealth Avenue (MM 67.8) for a project length of approximately 1.5 miles. Ma
Adams - Resurfacing and Related Work on A Section of Route 116
ERVING-GILL ORANGE-WENDELL RESURFACING AND RELATED WORK ON ROUTE 2     Work under this project will consist of milling the existing paved surface and repaving with 2 of HMA modified top course material. Work will also include repairs/upgrades t
Erving-Gill Orange-Wendell Resurfacing and Related Work on Route 2
LAWRENCE- BRIDGE BETTERMENT, L-04-009, HAMPSHIRE STREET OVER SPICKET RIVER     The project consists of replacing the existing structure with a prestressed box beam and concrete deck superstructure set on top of integral abutments in the same ap
Lawrence - Bridge Betterment (L-4-9) Hampshire St.-Spickett River
EASTHAMPTON/NORTHAMPTON- MANHAN BIKE TRAIL CONSTRUCTION, FROM EASTHAMPTON LINK TO EARLE STREET     This multi-use recreational rail trail project starts at Ferry Street in Easthampton and ends at Earle Street in Northampton, for a total length
Easthampton-Northampton- Manhan Bike Trail Construction, from Easthampton Link To Earle Street
TRANSPORTATION , MISSISSIPPI DEPARTMENT OF
SALEM- RECONSTRUCTION OF ROUTE 1A (BRIDGE STREET) FROM THE BEVERLY/SALEM BRIDGE TO WASHINGTON STREET (6000 FT.)     This project proposes to reconstruct Bridge Street (Route 1A) from the Beverly Salem Bridge to Washington Street.  The project i
Salem - Bridge St Reconstruction.  See also STP
Rt 29 West Amwell Twp Drainage, Construction
V&T RAILROAD FROM EUREKA MILL TO WEST SIDE OF FREHNER PIT PHASE 3A
Other Heavy and Civil Engineering Construction
Bridge Deck Replacement Program Rt 440, Ramp WK over Woodbridge Ave (CR 514), Construction
Despite the considerable advancements in our understanding of the mechanisms of acute and chronic pain, inadequate pain relief remains a major issue in chronic pain. Cannabinoid agonists acting on cannabinoid receptors (CBR) 1 and 2 have shown
Dartmouth-Hitchcock Medical Center - Borwell 508E, 512E
Current theories of drug abuse view addiction as a disease, but inevitably, the element of volitional choice will remain one of the key components of the illness.  The issue boils down to this:  why does an individual choose to use drugs even w
NEUROBIOLOGICAL CIRCUITS OF GAIN AND LOSS DURING RISKY DECISION  MAKING
Sickle cell nephropathy is a common complication of sickle cell disease that affects both children and adults, and may lead to kidney failure. The mechanisms that cause kidney damage in sickle cell disease are not well understood. We will study
THE PATHOGENESIS OF SICKLE CELL NEPHROPATHY
TITLE: Role of Syk and Rac2 in regulation of HIF1alpha and neovascularization Postnatal neovascularization plays a critical role in pathogenesis of numerous diseases e.g. diabetic retinopathy, tissue remodeling upon injury, rheumatoid arthritis
ROLE OF SYK AND RAC2 IN THE REGULATION OF HIF1A AND NEOVASCULARIZATION
HIV incidence among men who have sex with men (MSM) continues to rise in the United States, and over 50% of new US HIV infections in 2006 were among MSM. A recent CDC analysis suggests that over half of HIV transmissions among MSM are from main
ADAPTATION OF COUPLES VOLUNTARY COUNSELING AND TESTING (CVCT) FOR US MSM
Title:  SUPPORT OF YERKES NATIONAL PRIMATE RESEARCH CENTER One of the central goals of the Yerkes National Primate Research Center is to provide educational and training opportunities.  The Center is actively involved in training and continuing
SUPPORT OF YERKES NATIONAL PRIMATE RESEARCH CENTER
A C.elegans model for EPEC & EHEC Pathogenesis. The project is designed to understand evolutionarily conserved mechanisms by which the immune system detects pathogens. Here we use the model genetically maleable nematode Cenorhabditis elegans to
A C.ELEGANS MODEL FOR EPEC AND EHEC PATHOGENESIS
'Nox4 and cardiac fibrosis'. Congestive heart failure is a major cause of hospitalization (over 500,000 admissions per year) and affect over 5 million patients in US. In the current application we will study the mechanism of development and pro
This supplemental request encompasses activities of the Emory Epithelial Pathobiology Research Development Center core facilities and will update and add to essential components of the Morphology/Image Analysis Core (Core B) and Cell Culture an
EMORY EPITHELIAL PATHOBIOLOGY RESEARCH DEVELOPMENT CENTER
The scope of the CTOTC-02 collaborative encompasses unique barriers to successful kidney transplantation in children. Over the past forty years, the use of increasingly potent immunosuppressive drugs has lessened the risk for acute rejection (A
DEVELOPMENT OF TRANSPLANT STRATEGIES UNIQUELY RESPONSIVE TO THE NEEDS OF CHILDREN
This grant is providing summer and academic research experiences for high school students, college students and science educators in health-related scientific research. The research experiences were in support of a parental NIH grant that inves
AIDS Related Oral Candidiasis: Drugs, Sterols, and Fungal Cells (Summer Supplement)
TAS::57 3404::TAS RECOVERY - XUMU091375A - BASE-WIDE FACILITY PAINTING CONTRACT, VANDENBERG AIR FORCE BASE, CALIFORNIA.
This is a Public Housing Capital Fund Stimulus Formula grant.  It is for the replacement of roofs on fifteen (15) units.
Public Housing Capital Fund Stimulus (Formula) Recovery Act Funded
Community Facilities Loan for construction of Early Learning Center
Early Learning Center Building Construction Loan
Commercial and Institutional Building Construction
SR 5/BANKHEAD HWY/BILL ARP RD AT CS 573/ROSE AVE
Water and Sewer Line and Related Structures Construction
Highway Infrastructure Investment - Puerto Rico Highway Program.  The project consists in the a grade separation interchange for Highway PR-2 with Punto Oro Avenue, from km. 223.09 to km. 224.08, Stage 6, Phase II, Ponce.  This highway improvem
Conversion to Expressway PR-2 Interchange with Punto Oro Avenue, from km. 223.09 to km. 224.08
GOVERNMENT OF GUAM- DEPARTMENT OF ADMINISTRATION
Reconstruction and repair of three drainage culverts and one landslide along Route 2
CR 223/PORTAL HWY AT BIG BRANCH AND AT LOTTS CREEK 8 MI N OF METTER
This grant aided in purchashing three Lifepak 15 heart monitors.  The Clay County Ambulance Service provides care for 10,300 peoples in a 346 square mile area with the assistance of the Lizemore Volunteer Fire Departments ambulance.
Stewart Ave. Phase II from Las Vegas Blvd. to Main St.
Widening and reconstruction of Route 4 in vicinity of Ylig Bridge to Pago Bay
Route 4 Rehabilitation (Ylig Bridge to Pago Bay) and resurfacing (Ylig Bridge to Route 17)
ROCKMART STREETSCAPE ENHANCEMENT PROJECT - PHASE II
SR 13/BUFORD HWY FROM N OF DEKALB CO LINE TO SUGARLOAF PKWY
Improvements to Hagewood Water System, Inc. funded by USDA Rural Development, Water & Wastewater Loan & Grant.
SR 154/MEMORIAL DR FROM CANDLER RD TO MOUNTAIN DR
BAINBRIDGE DOWNTOWN STREETSCAPE - PHASE II
Professional, Scientific, and Technical Services
SR 8/US 29 AT PLEASANT HILL/LESTER ROADS
SR 138 AT 12 LOCS - UPGRADE TRAFFIC SIGNALS
CR 5157; CR 5158 AND CR 5200 AT 8 LOC - UPGRADE TRAFFIC SIGNALS
UPGRADE TRAFFIC SIGNALS AT 15 CR LOCS IN DEKALB COUNTY
S LAGRANGE LP FROM SR 109SE ALONG FLING AND PEGASUS TO SR219-PH II
Traffic Barrier Upgrades at Various Locations - District 5
Highway Infrastructure Investment Grant: Available for Use in Any Area (Flexible) and Areas with Population equal to or less than 200K
Resurfacing Various Locations in Allegheny County
Resurfacing Various Locations in Carroll County
Resurfacing Various Locations in Harford County
Resurfacing Various Locations in Prince George's  County (Laurel Shop)
Updating Existing Traffic Barrier and Design New Median Barrier - District 5
Updating Existing Traffic Barrier and Design New Median Barrier - District 3
Upgrading Existing Traffic Barrier and Design New Median Barrier - District 2
Highway Infrastructure Investment Grant:  Areas with Population equal to or less than 200K
ADA and Safety Improvemnts Various Locations in the Town of La Plata
DISTRICT 4; REPLACEMENT OF FAILING EXPANSION JOINTS OF VARIOUS BRIDGES ON STATE HIGHWAYS (CN).
Highway Infrastructure Investment Grant: Transportation Enhancements
Project will replace sewer lines in our collection system and provide for need upgrades at the Waste Water Treatment Plant to improve reliability and improve environmental safety.
US 16 Fm Spring Creek to Cathedral in RC
HARDWICK- NEW BRAINTREE- RESURFACING AND RELATED WORK,      Mill and resurface Route 32 (Main Street) from the Ware/New Braintree town line (milemarker 22.383) to just past the New Braintree/Hardwick town line (milemarker 23.38), a distance of
Hardwick - New Braintree - Resurfacing and Related Work on Route 32
BROCKTON - RECONSTRUCTION OF ROUTE 27, PLEASANT STREET AT WEST STREET AND WESTGATE MALL     Reconstruct Route 27, Pleasant Street, West Street and Westgate Mall Road.  Work includes minor widening, geometric improvements, new traffic signals an
Brockton - Reconstruction of Route 27, Pleasant Street at West Street and Westgate Mall
SOMERVILLE- SIGNAL & INTERSECTION IMPROVEMENTS AT MAGOUN SQUARE (BROADWAY, MEDFORD AND DEXTER STREETS)     This project includes new traffic signals, landscape and streetscape elements, including brick pavers, trees and street furniture.
Somerville- Signal and Intersection Improvements at Magoun Square (Broadway, Medford and Dexter Stre
Beam Bearing Repair Bridge #1875, PR-20 Guaynabo.  This improvement is clasified as  Bridge Rehabilitation with no added capacity.
Beam Bearing Repair Bridge #1875, PR-20 Guaynabo
Highway Infrastructure Investment Grant: Areas with Population equal to or less than 200K
The grant is part of a funding package to build the infrastructure of a rural water system to serve the residents of the north segment of the Fort Berthold Reservation.  This grant together with ND-91-30 is part of the same project.
North Segment New Town Area 1 & 3 Water Distribution Project
Department of Defense (except military departments)
Construct Central Chiller Loop, Bldg 5010
REGENTS OF THE UNIVERSITY OF CALIFORNIA AT RIVERSIDE
The purpose of this research is to develop a comprehensive model of the perception of 3D object motion. The recovery of object motion in a 3D environment is important for perceptual tasks such as the detection and avoidance of collisions and pe
Perception of Object Motion from Optical, Binocular and scene Information
Bicarbonate is a vital component of secretions from exocrine glands such as salivary glands, the pancreas, the duodenum, reproductive organs, sweat glands and the airways. It plays a critical role in numerous physiological functions such as dig
HCO3- CONDUCTIVE FUNCTION OF CFTR: IMPLICATIONS TO ORAL HEALTH & CYSTIC FIBROSIS
The overall objective of the grant is to develop a multifunctional image guided surgical (MIGS) platform to perform delicate and intricate surgeries. The MIGS platform integrates a high resolution depth-resolved imaging technique know as optica
MULTIFUNCTIONAL IMAGE GUIDED SURGICAL PLATFORM
ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND, THE
Over the past five years the Tulane National Primate Research Center (TNPRC) has successfully developed and expanded its specific pathogen free (SPF) rhesus monkey breeding colony. By the end of the current funding period the U24 SPF colony wil
ESTABLISHMENT AND EXPANSION OF SPF RHESUS COLONY
The goal of this project proposed for supplemental funding is the same as that of the parent grant (U42 RR016024): to increase the nation's capacity to produce Indian-origin rhesus monkeys (Macaca mulatta) that are specific pathogen-free (SPF)
ESTABLISHMENT OF A SPF RHESUS MACAQUE COLONY
Health Resources and Services Administration
The NFLP reports on an academic year basis and supports the establishment and operation of a loan fund within participating schools of nursing to assist nurses in completing their graduate education to become qualified nurse faculty. Participat
Federal Work Study Provides Need Based Financial Aid to Students
The Scholarships for Disadvantaged Students (SDS) program promotes diversity among health profession students and practitioners by providing scholarships to full-time students from disadvantaged backgrounds with financial need enrolled in healt
ARRA - SCHOLARSHIPS FOR DISADVANTAGED STUDENTS
forest wide trail maintenance northern presidential range (WMNF) trail network
My award title is HIV-INDUCED 5-LIPOXYGENASE: ROLE IN HIV-RELATED PULMONARY ATERIAL HYPERTENSION. My research aim is to determine whether HIV-1 increases the susceptibility of infected individuals to develop the non-infectious pulmonary vascula
HIV-INDUCED 5-LIPOXYGENASE: ROLE IN HIV-RELATED PU
Design of new treatment agents for drug abuse  The development of effective medications for the treatment of drug addiction disorders is of great importance to society.  Great advances have been made in the treatment of many CNS diseases that w
DESIGN OF NEW TREATMENT AGENTS FOR DRUG ABUSE
Tuberculosis (TB) is an enormous global public health problem including in the independent country of Georgia, a former Soviet republic, which has high rates of TB including drug-resistant TB (MDR- and XDR-TB).  This ARRA award is a supplement
Emory-Georgia TB Research Training Program
PROLIFERATIVE RESPONSES TO ENTERIC PATHOGENS IN INTESTINAL TISSUES Funding for the K01 parent grant was provided to study the protein Kruppel-like factor 5 (KLF5), a protein that promotes cell division/proliferation in the intestines.  Prelimin
PROLIFERATIVE RESPONSES TO ENTERIC PATHOGENS IN INTESTINAL TISSUES
REGULATION OF RAT RENAL INNER MEDULLARY FUNCTION. The major goal of the parent grant, 5R01DK041707, is to test two hypotheses: 1?? vasopressin rapidly increases UT-A1 accumulation in the apical plasma membrane; and 2?? vasopressin regulates UT-
REGULATION OF RAT RENAL INNER MEDULLARY FUNCTION
Epidemiology of Stress and GDM among Latin Women
Computational biology approaches to assessing the impact of amino acid residue substitution mutations on proteins.
Title: ARRA Increased Demand for Services Grant; Description: The IDS funds were to be used to fund the salaries of an outreach worker, an LPN, and retain our part-time pediatrician. The pediatrician resigned and we replaced her with a nurse pr
ARRA-Increased Demand for Services to Health Ctrs.
Offices of Physicians (except Mental Health Specialists)
This award has allowed us to do some things that we have put off that we considered non essential to the well being and comfort of the residents.  We have been able to replant some older trees with new healthy ones, as well as continue to work
The project this quarter is on the project course of action as detailed in the scope of work outlined in the contract award, with employees converting data into the systems for interaction.
The COPS Hiring Recovery Program (CHRP) provides funding directly to law enforcement agencies to hire and/or rehire career law enforcement officers in aneffort to create and preserve jobs, and to increase their community policing capactiy and c
'The COPS Hiring Recovery Program (CHRP) provides funding directly to law enforcement agencies to hire and/or rehire career law enforcement officers in an effort to create and preserve jobs, and to increase their community policing capacity and
TRANSPORTATION AND PUBLIC FACILITIES, ALASKA DEPARTMENT OF
Shore Avenue Rehabilitation & Erosion Protection
CR 203/GLISSON ROAD AT WOLFE CREEK 6 MI SOUTH OF METTER
Durango Rd. from Cheyenne Rd. to Alexander Rd.
Hillside Dr. from Sandhill Blvd. to Arizona State Line and Hafen from Abbott Wash to Town Wash
Bridge Repairs Allegheny Highland Trail over New Hope Road
CR 85/KIMBALL BRIDGE ROAD AT CR 103/WATERS ROAD
MCGINNIS FERRY RD EXT FROM L'VILLE-SUWANEE TO SATELLITE BLVD
ENFIELD; US ROUTE 5 OVER I-91; REHABILITATION OF BRIDGE 00445 (NO ADDED CAPACITY) (CN).
SUGARLOAF PKWY FROM SR 20 TO PEACHTREE INDUSTRIAL BLVD
Federal projects 0007035 and P112021 combined, involving the installation of retaining walls and  miscellaneous work at E & L Motors in Diamondville on U.S. Highway 189, in Lincoln County.
BUCHANAN TOWN SQUARE STREETSCAPE - PHASE II
SR 176/MARS HILL ROAD AT CR 55/MARS HILL CHURCH ROAD - GRTA
Highway Surface Transportation and Technology Training
ON-THE-JOB TRAINING AND SUPPORTIVE SERVICES PROGRAM - ARRA
Resurfacing Various Locations in Southern Anne Arundel County
Resurfacing Various Locations in Somerset County
Resurfacing Various Locations in Worcester County
Resurfacing Various Locations in Baltimore County East of I-83
Resurfacing Various Locations in Washington County
Traffic Detection at Signalized Intersections
Wetland Planting and Reforestation in District 3
Rehabilation and Resurfacing Various Locations in Prince George's County - CO No. 840-H(E)
Widening and Resurfacing Various Locations in Dorchester County
LINCOLN- RESURFACING AND RELATED WORK ON ROUTE 2     Work includes guardrail, painting and signage.
Lincoln - Resurfacing and Related Work on Route 2
DENNIS- RESURFACING & RELATED WORK ON ROUTE 6A      Mill and resurface Route 6A from the Yarmouth Town Line to the Brewster Town Line, a distance of approximately 4.3 miles.
Dennis- Resurfacing and  Related Work on Route 6A
NANTUCKET- RESURFACING AND RELATED WORK ON MILESTONE ROAD     Mill and resurface Milestone Road from just west of rotary that intersects Orange Street, Sparks Avenue, and Old South Road, to just east of rotary that intersects Post Office Road.
Nantucket - Resurfacing and Related Work on Milestone Road
NEW ASHFORD- RESURFACING & RELATED WORK ON ROUTE 7, FROM MM 41.68 TO MM 45.05     This project proposes to resurface Route 7 with hot-mix asphalt, and would also include repairing/improving the drainage system, resetting guardrail, upgrading gu
New Ashford - Resurfacing and Related Work on Route 7
CLINTON - BRIDGE REPLACEMENT (C-16-2) WATER ST. / NASHUA RIVER.        The proposed work under this project consists of bridge reconstruction, widening, guardrail installation and all other work on Water Street from its intersection with Bolton
Clinton - Bridge Replacement (C-16-2) Water St.- Nashua River.
Repair (upgrade) Controls, Multiple Facilities (Bldgs 1440, 2505, 129, 1630, 6000)
Recovery Funds were made available to the PA Internet Crimes against Children Task Force.The continued employment of 3 Detectives and 1 Det./Forensic Analyst are made possible through the Recovery Funds. There has been significant progress in t
Other Justice, Public Order, and Safety Activities
LOS ANGELES BIOMEDICAL RESEARCH INSTITUTE AT HARBOR-UCLA MEDICAL CENTER
Candida albicans is an opportunistic fungal pathogen that is able to survive as a commensal organism in several anatomically distinct sites. In compromised hosts, the manifestations of invasive infection caused by C. albicans vary based upon th
BCR1P AS A CANDIDA NEUTROPHIL RESISTANCE REGULATOR
Research and Development in the Social Sciences and Humanities
With the support of the Framework Program in Global Health, Dartmouth will undertake The Dartmouth Global Health Initiative: Growing a Multidisciplinary Framework program to develop a coordinated multidisciplinary curriculum and new educational
The Dartmouth Global Health Initiative: Growing a Multidisciplinary Framework
RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
This Faculty Early Career Award supports an integrated educational and research program addressing the fundamental electrical and optical properties of high-purity organic semiconductor devices, such as organic transistors and solar cells. Thes
CAREER: Charge and Energy Transport in Highly Ordered Small-Molecule Organic Semiconductors
To support the preservation of jobs that are threatened by declines in philanthropic and other support during the current economic downturn.
Arts and the American Recovery & Reinvestment Act of 2009
POLARITY OF REDOX CONTROL AND RISK OF INJURY IN THE ALVEOLAR EPITHELIUM   There is a significant difference in the concentrations and redox potentials between the fluid lining the epithelial surface and plasma for reduced and oxidized component
POLARITY REDOX CONTROL AND RISK OF INJURY IN THE ALVEO
Title: Patients' Experiences of Emergency Research: The PEER Study There is a critical need for clinical research on treatment of acute neurological conditions such as traumatic brain injury, seizures, and stroke. The National Institute of Neur
PATIENTS' EXPERIENCES IN EMERGENCY RESEARCH (PEER) STUDY
Title: Towards the development of a novel treatment for epilepsy.  The voltage-gated sodium channels SCN1A, SCN2A, SCN3A, and SCN8A are key regulators of neuronal excitability in the central nervous system (CNS). Mutations in SCN1A, SCN2A, and
TOWARDS THE DEVELOPMENT OF A NOVEL TREATMENT FOR EPILEPSY
Increasingly available and inexpensive high-throughput DNA sequencing holds great promise for biomedical research, but informatics challenge block the full realization of the potential of this transformative technology. In particular progress i
Dynamically scalable accessible analysis for next
HIV vaccine strategies have not yet succeeded in generating broadly neutralizing antibody responses in humans. A limited number of broadly neutralizing human monoclonal antibodies against HIV have been identified and have been the subject of in
DEFINING NEUTRALIZATION BREADTH IN HIV + HUMAN SERUM
General Magnitude Representation in Infancy: Testing the Associations among Space, Number, and Time   Abstract:  Space, number, and time provide fundamental sources of information by which we (and other animals) structure experience in the worl
UMDNJ-ROBERT WOOD JOHNSON  MEDICAL SCHOOL
This application addresses broad challenge area (04), clinical research, and specific challenge topic 05-CA-104, comparative effectiveness research on cancer treatment.  One in six American men will be diagnosed with prostate cancer in their li
Evaluate long-term prognosis of localized prostate cancer following initial radiation
Transplantation is the preferred method of treatment for many forms of end-stage organ failure. Current therapy in clinical transplantation relies on potent non-specific immunosuppressive drugs to inhibit rejection.  While short-term results ha
INTERACTIONS OF PROTECTIVE IMMUNITY AND TOLERANCE
Function of the Gamma HV68 M2 Antigen  This is a revised competing renewal of an R01 grant to characterize the function of the murine gammaherpesvirus 68 (MHV68) M2 antigen.  Gamma-herpesviruses are associated with the development of lymphoprol
The COPS Hiring Recovery Program (CHRP) provides funding directly to law enforcement agencies to to hire and/or rehire career and preserve jobs, and to increase thier community policing capacity and crime prevention efforts.
Cellular Signaling and Kidney Function     This supplemental funding application requests support for 4 undergraduate summer students for 2 years to participate in the research described in our program project grant P01-DK61521.  This PPG is a
was competetively renewed on April 1, 2008 for four years. This application was funded via the R01 investigator-initiated mechanism for four years. The central hypothesis of the parent grant continues to be that adiponectin protects against le
The Role of Leptin in Liver Fibrogenesis
Fostering Global Health Opportunities fro Emory and Its Partners Incorporating state of the art information and communication technologies (ICT) into Framework educational programs and activities is critical if Emory University is to remain amo
conduct modernization activities at various public housing developments. This funding can be expexted to result in providing employment for architects and engineers, construction workers and product manufacturers. In addition this funding can b
Other Foundation, Structure, and Building Exterior Contractors
The title of this award is Fundamental Structural Processes of Relaxation and Shear Transformations in Metallic Glasses. Compared with conventional metals and alloys which are all crystalline, non-crystalline (amorphous) bulk metallic glasses (
Fundamental Structural Processes of Relaxation and Shear Transformations in Metallic Glasses
Federal Work-Study provides need-based financial aid to students.
U.S. Army Corps of Engineers - civil program financing only
Remote Gate Control Systems Upgrade, Monongahela River, PA & WV  Point Marion, Charleroi, Maxwell, Morgantown, Hildebrand and Opekiska Locks and Dams
The State of North Dakota Department of Health was awarded a State Clean Diesel Program Grant to fund a project to replace approximately 40 school buses. The general purpose of the grant is to reduce diesel emissions and improve air quality.
ARRA Diesel State Grant Program-North Dakota Department of Health
Grant funds to be used with Applicant funds to purchase tanker for fire department.
TECHNICAL & ADULT EDUCATION, GEORGIA DEPARTMENT OF
Purchase and install CISCO networking equipment for student training on the Alma, GA campus
Training CIS students on CISCO networking equipment in Alma, GA
THE FUNDS WILL BE USED FOR SIDEWALK RENOVATIONS.
Renovation of Little Lake Grange #670 in Willits, CA. will be done using money received from the California Endowment. The USDA Communities Facilities grant will be used to purchase equipment that will complete the conversion of the exisiting f
Other Services (except Public Administration)
SR 3/US 41 FROM COBB CO LINE TO SR 293 CONN - MEDIAN TURN LNS
CR 560/ALEXANDER DRIVE FROM WASHINGTON RD TO RIVERWATCH PKWY
CR 223/PORTAL HIGHWAY AT LITTLE STOCKING HEAD CREEK
Gustavus Causeway Replacement (Bridge #1417)
Resurfacing Pegg Road from Forest Run Drive to Westbury Boulevard
Geometric Improvements Rosewick Road at Hertage Green Parkway
JONESBORO DOWNTOWN PED STREETSCAPE - PHASE I
This award was used to purchase kitchen equipment under the Community Facilities Projects.  An Early Childhood Education Center was constructed and completed this quarter.  The kitchen equipment needed for the building was purchased with this f
TALLULAH RIVER ROAD - PAVEMENT STABILIZATION
UPGRADE TRAFFIC SIGNALS AT 21 LOCS IN DEKALB COUNTY
Resurfacing Various Locations in Dorchester County
Resurfacing Various Locations in Wicomico County
Traffic Barrier Upgrades at Various Locations - District 1
Traffic Barrier Upgrades at Various Locations - District 4
Resurfacing Various Locations in Prince George's  County (Marlboro Shop)
Resurfacing Various Locations in Frederick County
Full Depth Concrete Repair at Transportation Weigh Inspection Stations
Updating Existing Traffic Barrier and Design New Median Barrier - District 4
Resurface Various Locations in Carroll County
Highway Infrastructure Investment Grant:  Urbanized Areas over 200K Population
Geometric Improvements at Allview Drive/Evans Trail
Construct Parking Lot Lighting, Bldgs 2300, 2301 and 2612
Emerging and established viral diseases take an enormous toll on human health.  Current treatment approaches are unlikely to halt epidemic spread of many viruses, notably HIV-1, due to prohibitive costs of treatment (i.e. access), compliance i
Developing Transmissable Antivirals by Exploiting Gene-Expression Circuitr
This project will develop and disseminate a key computational resource for integration of Near-Infrared Spectroscopy (NIRS) into Magnetic Resonance Imaging (MRI). The way to seamlessly use spectroscopy within MRI is to allow a flexible flow fro
UNIVERSITY OF VERMONT & STATE AGRICULTURAL COLLEGE
With this application for an Administrative Supplement, we seek to implement state-of-the-art technology to test hypotheses stated in Specific Aim 1 of our proposal (1R01AI080302: 'Molecular Regulation of HIV-1 Assembly, Release, and Cell to Ce
Molecular regulation of HIV-1 assembly, release and cell-to-cell transmission
X-linked spinal and bulbar muscular atrophy (SBMA, Kennedy's disease) is an inherited neuromuscular disorder characterized by lower motor neuron degeneration.  SBMA is caused by CAG/polyglutamine (polyQ) repeat expansions in the human androgen
MODELS OF SBMA MOTOR NEURON DEGENERATION
CTL ESCAPE AND REVERSION IN LINKED PAIRS Recent studies have demonstrated that HIV immune escape follows a predictable mutational path in response to an individual’s genetic environment, specifically an individual’s HLA alleles.  Since immu
NIH-CTL ESCAPE AND REVERESION IN LINKED PAIRS
Cardiac hypertrophy and the subsequent heart failure (HF) cause more than 260,000 deaths a year in The United States. Award Title:FUNCTIONAL COUPLING BETWEEN Ito AND Ica IN CARDIOMYOCYTES Recent studies demonstrated that the pathological increa
FUNCTIONAL COUPLING BETWEEN Ito Ica IN CARDIOMYOCYTES
In recent years, reactive oxygen species (ROS) have been shown to have critical roles in normal vascular function and the pathogenesis of vascular disease.  These molecules have profound effects on vascular smooth muscle cell (VSMC) growth, mig
NOXR1, A NOVEL REGULATOR OF NOX4-DEPENDENT CYTOSKE
Vitamin D Status in Pulmonary Fibrosis Idiopathic pulmonary fibrosis is a diffuse interstitial lung disease of unknown etiology characterized by chronic inflammation and progressive fibrosis and carries a 3-year, 50% mortality. Currently, there
The Role of JAM-A in Regulation of Intestinal Antigen Presenting Cells and Inflammation Numerous observations have suggested that inflammatory bowel disease is a multifactorial process encompassing at least three major interacting elements: env
THE ROLE OF JAM-A IN REGULATION OF INTESTINAL ANTIGEN
Each year, approximately five million people die from injuries, and millions more develop temporary or permanent disability, exacting a profound toll on the individual, family and society. Injury places a significant burden on countries with li
INTERNATIONAL TRAINING IN INJURY CONTROL RESEARCH
Ultrasonic Tissue-Typing-Guided Prostate Brachytherapy.   The purpose of this supplemental proposal is to increase the target number of patients in our clinical study by 40% (from 100 to 140), strengthening the statistical power of our parent g
This program will continue to study fundamental structural properties of the cell nucleus that support biological control and are disrupted in leukemia and metastatic breast cancer. We will gain insight into components of nuclear organization t
Title:  THE ROLE OF MOUSE ARL13B IN CELL DIVERSIFICATION   Cilia play well-established roles in motility and cell signaling in the mammalian nervous system. Our current understanding of how the neuroepithelium gives rise to specific neurons whi
THE ROLE OF MOUSE ARL13B IN CELL DIVERSIFICATION DURING SPINAL CORD DEVELOPMENT
Title: The Role Of Leukocyte Sequestration In The Control Of Viral Infections Abstract In the period immediately following infection, many viruses cause a transient, type I interferon-dependent lymphopenia. The reason that mammalian hosts adopt
THE ROLE OF LEUKOCYTE SEQUESTRIAN IN THE CONTROL OF VIRAL INFECTIONS
Allergy & Immunological Diseases Research
Transplant Tolerance in Non-human primates. This program project grant seeks to develop novel immunomodulatory strategies to induce immune tolerance after transplantation. Immune tolerance is defined as the acceptance of an allogeneic allograft
TRANSPLANT TOLERANCE IN NON-HUMAN PRIMATES
For the 100 years of its history, Fox Chase Cancer Center (FCCC) has been guided by a singular mission to reduce the burden of human cancer. Its 1904 hospital charter called for 'the study of the cause, treatment and prevention of cancer and fo
COMPREHENSIVE CANCER CENTER PROGRAM AT FOX CHASE
Title: Novel VLP vaccines for pandemic influenza virus (The ARRA award was made as a supplement to an ongoing project (AI068003). The 2009 influenza outbreak strain is the result of human infection with a new H1N1 strain of influenza virus cont
Supplement to Novel VLP vaccines for pandemic influenza virus
Neuronal cell culture is a cornerstone of neuroscience research and is used extensively in studies of brain and behavior. The in vitro environment offers researchers the opportunity to maintain neurons of interest under defined conditions and
High-Resolution Patterning of Neuron Cultures to Enable High-Throughput Assays
Administration for Children and Families
Supplemental Discretionary Award made by the American Recovery and Reinvestment Act for fiscal year 2009 to the Child Care Development Fund.  These funds will help support low income families with co payments for child care.  These funds also w
?Approaches to study the interactions among individual behaviors, social and physical environments, and genetic/epigenetic processes during critical developmental periods.?  Decades of animal physiology experiments unequivocally show that pertu
Epidemiology & epigenetics:  Maternal diet, DNA methylation, & offspring adiposity
Enclose 3 Sections of the picnic shelter @ the spillway overlook
SR 56/NAIL BRIDGE AT OHOOPEE RIVER 2 MILES W OF REIDSVILLE
SR 53 MEDIAN TURN LANES FROM EAST ROME BYPASS TO GORDON CO
SR 12/US 278 FROM SR 154/MEMORIAL DR TO CR 518/WEST AUSTIN DR
OAK GROVE ST. PAUL VOLUNTEER FIRE DEPARTMENT
The City is upgrading their existing water system and sanitary sewer system by removing and replacing deteriorated cast-iron water mains and clay sewer mains.  This will also include replacing the existing services lines to adjacent properties.
Water and Sewer Improvement District #2009-2, Phase 1
TOA Code 535 CF Combo (loan/grant) Construction of new highway garage
SR 10/MEMORIAL DRIVE FROM WOODCROFT RD TO GOLDSMITH RD
FUNDS TO BE USED FOR WATER TREATMENT PLANT UPDATES AND CHANGE THE CITY OF MAYVILLE'S WATER SOURCE FROM SURFACE TO GROUND WATER FOR BETTER QUALITY FOR THE RESIDENTS OF MAYVILLE
TRAILL REGIONAL WATER SYSTEM IMPROVEMENT DISTRICT NO. 26 PHASE 3A WATER TREATMENT PLANT IMPROVEMENTS MAYVILLE, ND
MILLEDGEVILLE HISTORIC DOWNTOWN STREETSCAPE - PHASE II
CITY OF WAYNESBORO GREENWAY PROJECT - PHASE II
SR 1/VETERANS PKWY FROM CS 2883/10TH ST TO SR 22 SPUR - PH II
Administration of Urban Planning and Community and Rural Development
DOWNTOWN ATLANTA PEDESTRIAN CORRIDOR IMPROVEMENTS-GRTA
SR 961; CR 3233 AND CS 3393 AT 8 LOCS - UPGRADE TRAFFIC SIGNALS
CS 757; CR 5155 AND CR 5156 AT 8 LOC - UPGRADE TRAFFIC SIGNALS
CR 42/ANTIOCH CHURCH ROAD AT PUDDING CREEK 4 MI NW OF PEARSON
SR 203/STRICKLAND STREET AT CR 309/OLD ALMA ROAD
Resurfacing Various Locations in Kent County
Install and Upgrade Signs Various Locations in Caroline County
UPS Installation in Various Locations in Montgomery County
FR HU20 FM NEAR THE W. STRIP INTC TO THE BEG OF US 95(MP AS SR 289) & US95 FM W. WINNEMUCCA BLVD INTC TO POTATO RD
TRUMBULL; RT 15; MEDIAN DECK REPAIRS; BRIDGE NO. 00750 OVER RESERVOIR AVE. (NO ADDED CAPACITY) (CN)
BRIDGEWATER- MIDDLEBORO- RESURFACING & RELATED WORK ON ROUTES 18 & 28,      Resurface Route 18/28 from Bridgewater Center to the Middleborough Rotary (intersection of Route 44) and make drainage improvements.
Bridgewater- Middleboro- Resurfacing and Related Work on Routes 18 and 28
BOURNE- COLD PLANING AND RESURFACING ON ROUTE 6 (SCENIC HIGHWAY)     Resurface Route 6 (Scenic Highway) from the intersection with Nightingale Pond Road to just east of the intersection with Bourndale Road.
Bourne- Cold Planing and Resurfacing on Route 6 (Scenic Highway)
WESTPORT- RESURFACING & RELATED WORK ON ROUTE 6     Resurface Route 6 from west of the Dartmouth town line (milemarker 20.9) to the Fall River city line (milemarker 16.3), a distance of approximately 4.6 miles.
Westport- Resurfacing and Related Work on Route 6
WILBRAHAM- BRIDGE REHABILITATION, W-35-003, RED BRIDGE ROAD OVER NE UTILITIES CANAL
Wilbraham - Bridge Reconstruction W-35-3 Red Bridge Rd. Utilities Canal
Repair (Upgrade) Windows at Multiple Facilities (Bldg 4000)
This Small Business Innovation Research Project will develop an innovative approach for epitaxial deposition of high quality thick (Al)(In)(Ga)N layers with low dislocation density. Accomplishment of the proposed effort will provide technology
SBIR Phase I: High quality AlGaN layers by fast growth rate MEMOCVD
surfactants applied  to organometallic catalysis is advanced in this proposal, and represents a variable essentially overlooked by the synthetic community. This technology also is to be applied to other important cross-couplings, such as amina
Early childhood temperament, particularly behavioral inhibition, is seen as an expression of a child's biologically based negative reactivity to novelty and threat. Behavioral inhibited children have difficulty with peer interactions and exhibi
THE EFFECTS OF EARLY TEMPERAMENT ON SOCIAL BEHAVIOR IN ADOLESCENCE
Chronic kidney disease (CKD) has become an important public health challenge in the United States. CKD is a major risk factor for end-stage renal disease (ESRD), cardiovascular disease (CVD), and premature death. Understanding novel risk factor
CLINICAL CENTER FOR PROSPECTIVE COHORT STUDY OF CRI
'FMRP-mediated translation regulation in neuronal development '                    The fragile X mental retardation protein (FMRP) binds mRNA and microRNA, is associated with polyribosomes, and is localized in dendrites and axons. Hence, FMRP i
FMRP- MEDIATED TRANSLATION REGULATION IN NEURONAL
'Identification of localized miRNAs for neuronal development and plasticity'. This research will advance our understanding of the critical importance played by miRNAs in local protein synthesis underlying neuronal development, which may be alte
Identification of localized miRNAs for neuronal
FEI TRANSMISSION ELECTRON MICROSCOPE WITH TOMOGRAPHY CAPABILITY The award is for an electron microscope, an instrument that can be used for new discoveries in biology or in the study of small structures. There is a dedicated group of scientists
FEI TRANSMISSION ELECTRON MICROSCOPE WITH TOMOGRAPHY CAPABILITY
Although Alzheimer’s Disease (AD) is an aggressive and devastating dementia that has an increased frequency with age and is one of the most common neurodegenerative diseases, it is remarkably difficult to diagnose with certainty, particularly
Novel PET Ligand for In Vivo Binding to Amyloid in AD
Streptococcus pyogenes, the group A streptococcus (GAS) is an important human pathogen that causes many types of disease, ranging in severity from 'strep throat' to severe invasive disease and streptococcal toxic shock syndrome. By elucidating
Diseases, Disorders & Medical Disciplines, General/Other
Parent Grant Title: Cellular Targets of Polyomavirus Transforming Proteins The expertise my laboratory has developed and the many reagents we have created have placed us in an outstanding position to help elucidate the roles and regulation of t
CELLULAR TARGETS OF POLYOMARVIRUS TUMOR ANTIGENS
Title: Supplement to Functional approach to communication sound processing in mouse auditory cortex  Early views of the adult auditory system describe it as a static processor of sound.  Ample evidence now demonstrates though that the adult aud
Functional Approach to Communication Sound Process
STRUCTURE FUNCTION STUDIES ON INTESTINAL EPITHELIAL JAM  Our proposed studies encompass detailed cell-biological approaches that have resulted in major advances in understanding the molecular basis of how JAM-A signals to regulate cell migratio
STRUCTURE FUNCTION STUDIES ON INTESTINAL EPITHELIAL
Cellular Responses to Radiation and Other Types of Damage  Radiation is responsible for mutation and genomic instability as a result of DNA strand nicks and breaks and misreplication of damaged DNA. This damage if not correctly repaired is resp
CELLULAR RESPONSES TO RADIATION AND OTHER TYPES OF
Excitation-contraction coupling in human ventricle development         Postnatal changes in the mammalian heart make it difficult to extrapolate pharmacological and surgical therapies from adults to infants. Excitation-contraction coupling is t
EXCITATION-CONTRACTION COUPLING IN HUMAN VENTRICLE DEVELOPMENT
This is an administrative supplement for R21 HL093665 (PI, V. Vaccarino), entitled “Sex Differences in Myocardial Ischemia Triggered by Emotional Factors after MI.” One third to two thirds of patients with CHD have myocardial ischemia that
ADMINISTRATIVE SUPPLEMENT TO SEX DIFFERENCES IN MY
Airport Improvement Program to reconstruct and rehabilitate approximately 40,000 square yards at the central and east side aprons, including water and drainage improvements.
Rehabilitate central and east side aprons (approximately 40,000 square yards), Construction, phase II
Molecular Imaging of G-Protein Coupled Receptors for Drug Development            Supplemental support is requested that will enable the research on structural studies of G-protein-coupled receptors to be accelerated and improved. The support fo
MOLECULAR IMAGING OF G-PROTEIN-COUPLED RECEPTORS FOR DRUG DEVELOPMENT
Office Healthy Homes and Lead Hazard Control
The purpose of the Lead Based Paint Hazard Control Grant Program is to assist States, Native American Tribes, cities/parishes, or other units of local government in undertaking comprehensive programs to identify and control lead-based paint haz
City of Sioux City Lead Based Paint Hazard Control Grant
The project outlines a comprehensive career plan for advancement of research and education in the field of active and cognitive hearing and speech technologies. The proposed research focuses on four main goals: (I) to design a novel architectur
Career: Cognitive Auditory Systems for Processing of Complex Acoustic Scenes
Green Mountain National Forest Trails Deferred Maintenance Project
GMNF Trails Deferred Maintenance Project
The purpose of this work is to implement construction activities at the North Dakota Arsenic Trioxide Superfund Site, which will provide a protective drinking water remedy to rural households in the project area.  The remedial action is for Seg
Administrative and Support and Waste Management and Remediation Services
Design and construction assistance for sewer system improvements in Pascagoula, MS
Department of the Army Corp of Engineers and City of Pascagoula Design and Construction Assistance for the Sewer System Improvements
Buena Vista Biomass Power, LLC (BVBP) is an 18.4 MW woody biomass renewable energy electric generation facility located near the community of Buena Vista, California approximately 40 miles southeast of Sacramento.  In 1999, due to a confluence
Buena Vista Biomass Power Economic Development and Job Creation
SR 31/US 221 AT SR 37 AND SR 11/US 129 EAST OF LAKELAND
rehabilitate water distribution system, and extend water main to bring water from Lake Linden to the community of Hubbell
VAIDEN-FRENCH CAMP ROAD; KNOX CROSSING ROAD
FOURTEENTH STREET FROM WEST PEACHTREE ST TO PIEDMONT AVE-GRTA
Restoration of Masso River Bridge embankments
Masso River Bridge Embankment Restoration
RESTORATION OF RAILROAD DEPOT - ROOF REPAIR
The City is upgrading the water system by removing and replacing deteriorated cast-iron water mains and lead services.  This will also include replacing and added additional hydrants adjacent to the new water main and upsizing existing water ma
Water Main Replacement District No. 2009-1
SPALDING COUNTY SIGNAL UPGRADE PROGRAM - PHASE I
MIDTOWN ATL SIGNAL AND INTERSECTION IMPROVEMENTS PH II - GRTA
SR 139 AT 4 LOC AND CR 2570 AT 1 LOC - UPGRADE TRAFFIC SIGNALS
SR 223 AT EUCHEE CREEK 2.2 MI NW OF GROVETOWN
CR 85/KIMBALL BRIDGE RD AT BIG CREEK 2 MI SE OF ALPHARETTA
SR 16/WELLS STREET AT CR 157/BROAD ST AND LUTHER BAILEY ROAD
Resurfacing various locations in Calvert County
Resurfacing Various Locations in Cecil County
Traffic Barrier Upgrades at Various Locations - District 2
Traffic Barrier Upgrades at Various Locations - District 3
Resurfacing Various Locations in Baltimore County West of I-83
Resurfacing Various Locations in Caroline County
Highway Infrastructure Investment Grant: Urbanized Areas over 200K Population
Clean/Paint 10 Existing Bridges in Prince George's County
Clean/Paint Various Bridges on US 1, MD 201, MD 202, MD 212, and MD 500
Upgrading Existing Traffic Barrier and Design New Median Barrier - District 1
Resurfacing Various Location in Calvert County
Cleaning and Painting Various Bridges in Frederick County
Pavement Marking Various Locations in Dorchester County
Safety and Resurfacing Various Locations in Montgomery County
Shoshone & Death Valley Polymer AC Overlay
The City is replacing existing sanitary sewer piping and a sanitary sewer lift station. Sanitary sewer service piping will be replaced to the property lines. Sidewalks, pavement and curb and gutter removed due to the sanitary sewer construction
Sanitary Sewer Replacement District 2009-1
Interstate Route H-1, Concrete Pavement Preservation, Dowel Retrofit, M.P. 2.40 to M.P. 3.46 and M.P. 24.90 to M.P. 26.40 (Palailai and Kaimuki Areas)
The cutaneous microcirculation plays a central role in a range of skin diseases that are characterized by epidermal hyperproliferation or cutaneous inflammation. Many of these diseases are typified by increased vascular permeability, leading to
CADHERIN REGULATION IN DERMAL ENDOTHELIAL
Administrative Supplement  - The purpose of the supplement is to pursue the knockdown of Siglec-5 in chimpanzee T cells using small interfering RNA.  The student will work an experienced postdoc in the lab to optimize this knockdown first in mo
GENETIC MODULATION OF BLOOD AND VASCULAR GLYCOSYLATION
Hypertension is a leading cause of death and disability affecting over 50 million people in the United States and responsible for 200,000 deaths annually. Because hypertension and associated cardiovascular diseases are prevalent in Louisiana, T
TULANE COBRE IN HYPERTENSION AND RENAL BIOLOGY
The prospect of prophylactov treatment of a large number of people with small pox antiviral agents raises the possibility of a significant degree of toxicity to the kidney and other organs. Since the basolateral Oast and other apical multispeci
SNPS IN HANDLING OF SMALL POX ANTIVIRALS AND OTHER DRUGS
Impact of Video Viewing on Infant Learning: Using Baby Signs as an Experimental Approach   The American Academy of Pediatrics recommends that children under two refrain from watching television or videos on the grounds that infant viewing is po
IMPACT OF VIDEO VIEWING ON INFANT LEARNING:  USING
The Personal Responsibility and Work Opportunity Reconciliation Act (PRWORA) of 1996, often referred to as welfare reform, ended entitlement to welfare benefits under Aid to Families with Dependent Children (AFDC) and replaced AFDC with Tempora
employed to assess the severity of coronary disease in symptomatic patients, reveals only the degree of luminal narrowing, and fails to visualize the arterial wall. Additionally, arterial remodeling prevents many plaques from being detected by
The title of this award: REPAIR OF CLUSTERED DNA DAMAGES.  Melanoma is the most fatal form of skin cancer.  Despite much research has been directed to identify the etiological factors that lead to melanoma formation,  it is still not clear what
ADMIN SUPPLEMENT - HER-2/IGF-IR CROSSTALK AND HERCEPTIN  The her2 gene is overexpressed in approximately 30% of metastatic breast cancers, and is associated with rapid disease progression and poor survival. Herceptin, a recombinant humanized an
ADMIN SUPPLEMENT - HER-2/IGF-IR CROSSTALK AND HERC
Currently, the most accurate experiment approach to quantitatively measure gap junction mediated biochemical coupling is the LAMP assay. The LAMP method is noninvasive and offers excellent temporal resolution. The dyes used in LAMP have high ul
Neutrophil interactions with intestinal epithelial cells The etiology of human inflammatory bowel disease (IBD) includes both aberrant leukocyte responses and epithelial barrier dysfunction. Junctional Adhesion Molecule (JAM) family of proteins
NEUTROPHIL INTERACTIONS WITH INTESTINAL EPITHELIAL CELLS
The purpose of the funding is to provide employment for on additional resident in an already existing veterinary training program, thus increasing the return on investment from the parent R25 supported program, while offering a new employment o
YRPC NONHUMAN PRIMATE CLINICALMEDICINE RESIDENCY PROGRAM
TRAINING IN SYSTEMS AND INTEGRATIVE BIOLOGY: NEUROSCIENCE: This award will support three addditional outstanding predoctoral students in the interdepartmental Graduate Program in Neuroscience at Emory University for the next two years. The obje
TRAINING IN SYSTEMS AND INTEGRATIVE BIOLOGY-NEUROSCIENCE
This award is an administrative supplement for a Career Transition Award from the Center to Reduce Cancer Health Disparities at NCI to promote the advancement of minority scientist towards independence and research on health disparities related
TUMOR ENDOTHELIUM MARKER 8 ADHESION IN TUMOR
The focus of the parent grant is to study the role of ?? T cells in the immune response to infection with Borrelia burgdorferi.  Despite our knowledge of the existence of ?? T cells for 25 years, we still know very little regarding their contri
The Atlanta Clinical and Translational Science Institute's (ACTSI) community engagement efforts strive to increase the capacity of communities to participate in clinical and translational research. ACTSI's Community Engagement and Research Prog
ATLANTA CLINICAL AND TRANSLATIONAL SCIENCE INSTITUTE (UL1)
Kealia Fire Station Photovoltaic Power System and Energy Efficiency Improvements
Management, Administrative & Technical Support
Recovery Construct Roads @ Englebright Dam
Early Learning Center Building Construction
Construction of Head Start Early Learning Center
Grant funds to be used with Applicant funds to purchase a new fire truck for fire department.
TRANSPORTATION, RHODE ISLAND DEPARTMENT OF
Reconstruction of Rte 4 and US Rte 1,US Rte 1 Median Landscaping
CR 76/OLD GA 39 AT DRAG NASTY CREEK 9 MI N OF FORT GAINES
SR 520 FROM W OF BRANTLEY CO LINE TO CR 21/EMANUEL CHURCH RD
TOA Code:  535  CF Combo (loan/grant)  Purchase new fire truck.
Community Facility Grant Tractor/Mower Purchase
The funds will be used to do ADA improvements to the facility and window improvement to help with heating/cooling issues
Improvemnts to the Lincoln Center Facility
Safety and Resurfacing Pleasantville Road from Baltimore County Line to Highpoint Road
SPALDING COUNTY SIGNAL UPGRADE PROGRAM - PHASE II
Off-System Bridge - Maple River, 6 miles East & 6 miles south of Alice
SR 176/LOST MTN AT CR 809/CORNER ROAD - GRTA
Traffic Barrier Upgrades at Various Locations - District 7
Updating Existing Traffic Barrier and Design New Median Barrier - District 6 & 7
Traffic Signal Reconstruction MD 7, MD 45, MD 157 and MD 700
Rehabilation and Resurfacing Various Locations in Prince George's County - CO No. 839-H(E)
Highway Infrastructure Investment Grant:  Available for Use in Any Area (Flexible) and Urbanized Area over 200K Population
Resurfacing Various Location in Cecil County
Pavemment Marking Various Locations in Caroline County
Safety and Resurfacing Various Location in Charles County
Milling and Resurfacing Various Locations in Chestertown
Sunflower Valley Ultra Thin Bonded Wearing Course (BWC)Seal Coat
Valdez Bike and Pedestrian Path Enhancements
TOA Code 545, Waste combo (loan and grant) - Rural Development funds will be used to expand and upgrade the Villages current wastewater treatment facility.
Interstate Route H-1 Seismic Retrofit, Farrington Highway Separation & Makakilo Drive Separation
Revolving Loan Fund to Facilitate Small and Emerging Business
Rural Business Enterprise Grant to Establish a Revolving Loan Fund for City of Wells Businesses
Community Development, Business & Industry
CHESHIRE- RESURFACING & RELATED WORK ON ROUTE SR 8, FROM LANESBOROUGH T.L. TO MM 51.0     The proposed scope for this project consists of micro-milling Route 8 shoulders and partially into travel lanes, installing a stress absorbing interlayer
Cheshire - Resurfacing and Related Work on Route 8
grant for furniture/equipment for Talbot Senior Center
TR 137, Sand Ridge Road, Meridian Township
From East of the Cheyenne River to near SD 73 East Jct
Effects of mGluR2/3 Activation on Cue-Induced Cocaine Relapse in Squirrel Monkeys  Despite substantial efforts, there are currently no FDA-approved pharmacotherapies available for the treatment of cocaine abuse or dependence. A prominent featur
EFFECTS OF MGLUR2/3 ACTIVATION ON CUE-INDUCED COCAINE RELAPSE IN SQUIRREL MONKEYS
Dietary Inorganic Phosphate as a Target for Nutritional Intervention in Cancer It is becoming increasingly apparent that diet can have profound effects on functional genomics. However, this area of research has only begun to be exploited for th
DIETARY INORGANIC PHOSPHATE AS A TARGET FOR NUTRITIONAL INTERVENTION
This award titled: 'NUCLEAR MAGNETIC RESONANACE SPECTROSCOPY BASED METABOLOMICS' is funded under the American Recovery and Reinvestment Act of 2009 (ARRA) to develop a novel metabolomics approach that may improve the early diagnosis of Alzheime
NUCLEAR MAGNETIC RESONANACE SPECTROSCOPY BASED MET
This project will investigate the efficacy of UBS109, a water soluble nuclear factor kappa B (NF-kB ) antagonist structurally related to curcumin, the principal curcuminoid of the Indian curry spice turmeric, to block CNS and behavioral changes
DEVELOPMENT OF A NOVEL NF-KAPPAB ANTAGONIST TO BLOCK CYTOKINE-INDUCED BEHAVIOR
Factor VIII (fVIII) is the protein that is missing or deficient in patients with hemophilia A. The development of inhibitory antibodies (Abs) to fVIII currenlty is considered the most significant complication in the management of patients with
STRUCTURE AND FUNCTION OF THE FACTOR VIII
Expand the use of equipment and technology to improve the effectiveness of operations and evidence collection. The Agency will purchase new or replace outdated equipment to improve the effectiveness of patrol operations and improve the ability
The mammalian intestinal epithelium is a dynamic system in which cell proliferation is closely linked to differentiation and cell death. Studies have identified several important pathways such as Wnt, Notch, BMP and hedgehog that are involved i
REGULATION OF INTESTINAL EPITHELIAL CELL PROLIFERA
This summer student research will support and accelerate aim-3 of the parent grant to identify the cause of exaggerated glutamate receptor signaling at synapses in a mouse model of fragile x syndrome. This research will provide students with tr
Imaging FMRP Regulation and Function Admin. Supp.
The purpose of the funding was to create a position for a student to obtain research experience in the summer and fall of 2009.  The funding allowed the student to perform added analysis on previously collected clinical trial data.  The added
Detection of LV dyssynchrony by Cross-Correlation
The title of the award is: Comparison of B Cell Differentiation in Mice and Humans. Our previous studies indicated that human B cells, but not mouse B cells, preferentially express immunoglobulin Fc Receptor-Like (FCRL) transmembrane receptors
COMPARISON OF B CELL DIFFERENTIATION IN MICE AND HUMANS
We are proposing a predoctoral training program in Biostatistics in Genetics, Immunology, and Neuroimaging (BGIN). In this program, students will learn to develop statistical and computational innovations applied in one of three areas of concen
BIOSTATISTICS IN GENETICS IMMUNOLOGY NEUROIMAGING
SPF Breeding Colonies at the Yerkes NPRC – Supplement Support to enable us to better characterize the MHC region of the specific pathogen free (SPF) colony of rhesus macaques housed at the Yerkes National Primate Research Center  by using a t
SPF BREEDING COLONIES AT THE YERKES NPRC - SUPPLEMENTAL
Atlanta Clinical and Translation Science Institute (UL1): Supplement to the Translational Technologies and Resources Program to Advance Innovation through Imaging  The Translational Technologies and Resources (TTR) Program of the Atlanta Clinic
ATLANTA CLINICAL AND TRANSLATIONAL SCIENCE INSTITUTE - P
Heart City Health Center (HCHC) will increase its efficiency and ability to serve its community through a construction project that will create a 1500 SF addition on the rear of the existing building  to combine with the adjacent 2100 SF clinic
This project will fund chemical engineering trainees, especially graduate students, to understand how to develop integrated self- and directed- assembly mechanisms to robustly assemble multi-component colloidal systems into more ordered and div
Integrated Self & Directed Assembly of Multi-Component Colloidal Structures
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). This research is intended to achieve new, useful insights into control of noise pollution from jet aircraft by studying turbulent reactive flows a
CAREER: Fundamental Analysis and Computational Modeling of Acoustic Radiation in Turbulent Reacting Flows
The purpose of this work is to implement construction activities at the North Dakota Arsenic Trioxide Superfund Site, which will provide a protective drinking water remedy to rural households in the project area.  The remedial design is for Seg
Grant funds to be used with RD loan and Dept of Commerce grant funds to build a new fire station.
Wild Rose Area Fire Department - Fire Station
CR 134/COUNTY LINE ROAD AT POLECAT CREEK AT MURRAY CO LINE
Traffic Signals at Various Locations, Phase 10
Highway Infrastructure Investment Grant: Available for Use in Any Area (flexible), Rural Areas with Population under 5K
Branford: Reconstruction of Bridge # 00340 (AMTRAK RR bridge over us1)
The award will be used to develop and provide incentives and rebates to homeowners, rental property owners and businesses for comprehensive energy tests and home performance improvements under the Berkeley Energy Initiative.  The proposed p
Berkeley Energy Initiative (Money for Energy Efficiency)
TOA Code: 535 CF Combo (loan/grant) Purchase new ambulance.
TOA Code: 535 CF Combo(loan/grant); Purchase pumper truck.
Energy Efficiency and Conservation Block Grant
Community Facility Grant Vehicle Purchase
Lamb Blvd. from Charleston Blvd. to Owens Ave.
Hills Center Dr. from Village Center Circle to Lake Mead
Safety and Resurfacing Cash Valley Road from US 40 to MD 36
3CR 5190/SOUTH AND NORTH HAIRSTON ROAD AT 7 LOCS
TOA Code:  535  CF Combo (loan/grant) Construction of new fire station. Loan amount $879,000.00 Loan Number 97-07 Grant award $25,000.00 number NY-00-09
HERMON VOLUNTEER FIRE DEPARTMENT- FIRE STATION
CS 508/LEE ST FROM CS 568/WILLIAMSBURG WAY TO SR 54
ELLAVILLE SIDEWALK PROJECT IN SCHLEY COUNTY
SR 20/LOGANVILLE HIGHWAY FROM OZORA ROAD TO BRAND ROAD - GRTA
SR 176/MARS HILL ROAD AT CR 784/HADAWAY ROAD - GRTA
SR 314 AT 3 LOCS - UPGRADE TRAFFIC SIGNALS
SR 135/US 221 AT TIGER CREEK APP 6 MI NE OF DOUGLAS
SR 15 AT CR 347/MATTHEWS ROAD IN TENNILLE
Resurfacing Various Locations in St Mary's County
Resurfacing Various Locations in Queen Anne's County
Resurfacing Various Locations in Talbot County
Wetland and Tree Plantings Various Locations District 4 and District 5
Wetland Planting and Reforestation in District 5
Traffic Signal Reconstruction MD 2 and MD 710
Guardrail Replacement and Installation in Various Locations in Quenn Anne's County
Safety and Resurfacing Various Locations in Frederick County
Resurfacing Various Local Routes in Washington County
Resurfacing Various Location in Baltimore County
Upgrade Traffic Signs in Various Locations in Montgomery County
SR 7/US 41 AT GIDDENS MILL CREEK IN NORTH ADEL
HVAC System replacement for Community Building/Armory
GlouCo - CR 536 (aka Rt. 322) from CR 623 to CR618 in Harrison Township.
SOUTH DAKOTA SCHOOL OF MINES & TECHNOLOGY
I-5/SR 532 vicinity to Starbird Rd vicinity - Concrete Rehab
Bridge Deck Replacement Program Rt 4 over Flat Rock Brook, Design
CR 107/HOWELL BRIDGE RD AT SHARP MTN CREEK SW OF BALL GROUND
US 78:  UPGRADE TO INTERSTATE STANDARDS MCCULLOUGH BLDV @ BELDEN TO US 45
BOARD OF TRUSTEES OF COMMUNITY-TECHNICAL COLLEGE
The purpose of this study is to develop a communication interface that will enable older people to effectively communicate with robotic assistants, allowing them in this way to remain living safely in their homes. The proposed communication int
HHC RI Medium Collaborative Research Effective Communication with Robotic Assistants for the Elderly Integrating Speech Vision and Haptics
Minnesota Environmental Initiative was awarded a National Clean Diesel Funding Assistance grant to fund a retrofit, replacement and repower project or program targeting 590 on-road and off-road diesel vehicles in Minnesota. The general purpose
Project Green Fleet - American Recovery and Reinvestment Act
Community-Wide Environmental Assessment Cooperative Agreement
REDEVELOPMENT AUTHORITY OF THE CITY OF MILWAUKEE
Stimulus funding to conduct city-wide Brownfields Relvovling Loan Fund loans and /or subgrants to eligible entities for contaminated sites where redevelopment will create jobs and new tax base and improve conditions in the city.
HOLCOMB BR RD FROM OLD HOLCOMBE BR RD TO E OF SR 400(INCL BRS)
HOUSING AUTHORITY OF THE CITY OF PINEVILLE
EXECUTIVE OFFICE OF THE GOVERNMENT OF THE VIRGIN ISLANDS
TRANSPORTATION AND DEVELOPMENT, LOUISIANA DEPARTMENT OF
US 98 from Walthall CL to the west end of the Tylertown Bypass (EB & WB Lanes)
FRIENDS OF THE LIBRARY OF PHILIPSBURG, PENNSYLVANIA, INC. THE
Award for facility acquisition and removation
Friends of the Library of Philipsburg, PA
US 84 from 7.5 miles East of Adams CL to west end of Bude-Meadville Bypass (EB & WB Lanes)
EXECUTIVE OFFICE OF THE COMMONWEALTH OF KENTUCKY
SR 8 Bolivar County Hospital to Ruleville
GlouCo - CR655 Fries Mill Road from CR 689 to Rt. 322 in Washington & Monroe Townships.
Landslide Correction PR-173, km 3.0, Cidra.  This highway improvement is clasified as a Restoration and Rehabilitation (4R) Project
Landslide Correction PR-173, km. 3.0, Cidra
FAYETTE BUSINESS AND INDUSTRIAL DEVELOPMENT CORPORATION
The purpose of the investment is to assist in the enhancement and marketability of 168 acres of an existing 300 acre industrial park. The project elements include overlayment of 4,000 +/- lf of existing road surface and the reconstruction of 8,
Fayette Business Park Road and Infrastructure Improvement Project
Hawaii Belt Road, Clean and Paint Steel Members, Ninole, Maulua, Kuwaikahi and Kukaiau Bridges
I-19; Rio Rico Rd TI - Chaves Siding Rd TI
This award provides for ARRA Cost of Living Adjustments (COLA) and Quality Improvement Funding for the Head Start and Early Head Start Programs operated by EDUCATION CONNECTION in Connecticut.
ACTION FOR BOSTON COMMUNITY DEVELOMENT, INC.
ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act.  Head Start promotes the school readiness of low-income children through the provision of comprehe
WORCESTER COMMUNITY ACTION COUNCIL, INC.
This award provides for ARRA Cost of Living Adjustment (COLA) and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start and early Head Start Programs. Head Start promotes the sc
THAMES VALLEY COUNCIL FOR COMMUNITY ACTION, INC.
Head Start ARRA award was to provide a Cost Of Living Adjustment to staff and to provide additional outdoor equipment on the playgroud. We also added more computers for the classrooms and staff. Additional training was provided for their specif
COMMUNITY ACTION PROGRAM BELKNAP AND MERRIMACK COUNTIES, INC.
This award provides for ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start and/or Early Head Start program.  Head Start promotes th
KENNEBEC VALLEY COMMUNITY ACTION PROGRAM
The ARRA funds were used to support COLA/Merit for Early/Head Start staff (102 staff). Quality improvement funds were used to improve staff qualifications to meet standards established under section 648(a)(1) of the Head Start Act.    Addit
SOUTH MIDDLESEX OPPORTUNITY COUNCIL, INC.
Financial Assistance Award : Cost-of-Living Adjustment (COLA) increase of 1.84% in the amount of $47,660 for Head Start to pay for staff salaries. Quality Improvement funds of $140,589 for Head Start consistent with the provisions of Section 64
COLA:  CFO received ARRA funds via DHHS/ACF, Office of Head Start, which must be utilized to provide a 1.84% COLA to all Head Start funded employees. No units of measure associated.
Head Start Quality Improvement and COLA (ARRA)
CMC 221 - From10 Miles South of Valley City, N
SR 15 FM N CONN OF SR 15 BYPASS TO PONTOTOC CL
Highway Infrastructure Investment - Highway resurfacing - From funding for use in any Area (flexible)
Highway Infrastructure Investment Grant: Rural Areas with Population under 5K
SR 289, WINNEMUCCA BLVD, FROM MELARKEY(US 95) TO JCT I 80
HOPES CAP, Inc.  applied and received funding  in the amount of $237,093 for Quality Improvement and ARRA COLA  from the Office of Head Start to support its Head Start program serving 442 children in Hoboken and Plainfield, New Jersey. The HOPE
NORTH HUDSON COMMUNITY ACTION CORPORATION
?Head Start/Early Head Start COLA, Quality Improvement? to low income children and their families. A COLA increase of 1.84% in the amount of $56,917 for Head Start and $12,341 for Early Head Start.  These funds must be obligated to pay for appr
ARRA Cost of Living Adjustment(COLA), and Quality Improvement Funding consistent with the provision of Section 640(a)(5) of the Head Start Act. The NYF-PR HS and EHS programs continue to serve four municipalities namely; Catano, Coamo, San Juan
Head Start and Early Head Start FY'09 ARRA COLA & QI
NEW YORK STATE FEDERATION OF GROWERS & PROCESSORS ASSOCIATES INC
ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5)of the Head Start Act.
ULSTER COUNTY COMMUNITY ACTION COMMITTEE INC
This award provides for ARRA Cost of Living Adjustment (COLA), and Quality Improvement funding consistent with the provisions of Section 640 (a) (5) of the Head Start Act for the Head Start and Early Head Start program.  Early Head Start/Head S
FY2009 ARRA COLA/QI (Head Start & Early Head Start Program
SCHENECTADY COMMUNITY ACTION PROGRAM INC
Schenectady Community Action Program, Inc. (SCAP) Head Start has been in operation since 1965 and currently serves 276 children three to five years old.  There are 256 children in a Center Based program and 20 children in a Home Based program.
VIRGIN ISLANDS DEPARTMENT OF HUMAN SERVICES
The Head Start Program received one-time stimulus funding to be given to all Head Start employees.  The funds received represent 1.84% of the federal personnel reported.  Head Start Program in the Virgin Islands utilizes the Highscope Curriculu
To promote school readiness by enhancing the social and cognitive development of children through the provision of educational, health, nutritional, social and other services to enrolled children and families, FY 2009 ARRA COLA/QI was received
CENTRO DE FORTALECIMIENTO FAMILIAR DE PUERTO RICO INC
Award will be used to supplement the staff's income through Cost of Living Allowance (COLA) distributions ($12,158.00), to improve the staff's qualifications through training and professional development courses ($26,500.00) and to ensure that
This award was to benfit our Head Start Program with cola increases as well as salary increases for employees compared to other programs with the same job description. It is also to improve the quality of our Head Start Program.
Provided Head Start services for 146 preschool children and families in Columbia County in New York.
YELED V'YALDA EARLY CHILDHOOD CENTER INC.
ARRA project award expanded services to 108 Head Start children and 100 Early Head Start children, families, and expectant mothers in Brooklyn and Staten Island, New York, with both center-based and home-based program options.
ARRA HEAD START EXPANSION GRANT. HEAD START PROVIDES FAMILY SERVICES FOR LOW-INCOME FAMILIES WITH VERY YOUNG CHILDREN TO PROMOTE THE HEALTHY DEVELOPEMENT OF THE CHILDREN AND FAMILIES.  THE GRANT AWARD COVERS SEVEN ADDITIONAL CLASSROOMS, INCLUDI
thick Portland Cement Concrete Pavement. The bridge portion will be approximately 217 feet wide by 226 feet long.
Kaahumanu Avenue, Waiale Road Overpass Repairs
US 36 Chip Seal From Lyons To Estes Park
Replacement of the Wyoming Bridges No. 43 & 44
I-5, Marysville to Stillaguamish River - ITS
CR 186/HAGIN STILL ROAD AT OCHLOCKONEE RIVER SE OF DOERUN
US 49 from 1.5 mi. N of Seminary then run north for 17.6 miles (NB Lane)
Poured Concrete Foundation and Structure Contractors
This award supports the repowering of four ship's service generator sets on two Great Lakes bulk cargo vessels, replacing older diesel engines with newer, cleaner engines to significantly reduce harmful emissions. Replacement with new equipment
The Hamilton County Board of County Commissioners was awarded a National Clean Diesel Funding Assistance Program Grant to fund a project targeting 60 school buses in Hamilton County Ohio.  The general purpose of the grant is to reduce diesel em
ARRA - Clean Diesel National Program - Hamilton County
Highway Infrastructure Investment Grant: Avialable for Use in Any Area (flexible)
Highway Infrastructure Investment - Bridge replacement, no added capacity (no added travel lanes) - From funding for use in any Area (flexible)
SR 8 FROM CLEVELAND TO SUNFLOWER C.L. (ADD 2 LNS) & SR 8 FROM BOLIVAR C.L. TO RULEVILLE (ADD 2 LNS)
The $800,000 EDA grant will help build Energy House on Delaware Technical & Community College's Owens Campus in Georgetown, DE. Energy House will be a learning center for alternative technologies, focusing on renewable energy products for homes
The construction of water and sewer infrastructure for new technology park will be a project coordinated with the new regional fiber optic backbone and will lead to the development of the Mid Shore Technology Incubator.  The $3 million investme
FAS 189 and FAS 79, Milledgeville and Freeport Rd
COMMUNITY ACTION AGENCY OF SOMERVILLE INC
ARRA Cost of Living Adjustments (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act.
ANDROSCOGGIN HEADSTART & CHILD CARE, INC
Head Start Early Head Start for ARRA Cost of Living Adjustment (COLA) and Quality Improvement Funding to promote school readiness of low-income children through comprehensive health, developmental and family services.
WEST HAVEN COMMUNITY HOUSE ASSOCIATION, INCORPORATED, THE
ARRA Cost of Living (COLA) and Quality Improvement Funding consistent with the provisions of Section 540(a)(5) of the Head Start Act.
Required 1.84% COLA to Head Start staff for July 1, 2009 through June 30, 2010 will be $50,018 of the award.  The rest is for quality improvements.  Our Head Start and Early Head Start program needed to make some modifications in order to conti
This award provides for ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start and/or Early Head Start program. Head Start promotes the
Head Start, Early Head Start Cola & Quality Improvement Funds- The cost of living adjustment (cola) increase of 1.84% in the amount of $51,038 for Head Start and $24,035 for Early Head Start, these funds were used to pay cost of living increase
YORK COUNTY COMMUNITY ACTION CORPORATION
ARRA Cost of living (COLA) in the amount the 1.84% to be applied in a twelve month period beginning July, 2009 to be given to all Head Start and Early Head Start staff.  Further, Quality Improvement funds to be spent in the award period from Ju
UNITED COUNSELING SERVICE OF BENNINGTON COUNTY INC
ARRA Cost of Living This award provides for ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Headstart Act for the Head Start program.  Head Start promotes the sch
EASTCONN supports 13 sites where the Head Start and Early Head Start programs are being held, including center based, home based, and combination options in the towns of Putnam, Plainfield, Killingly, and Windham in Windham county, and the town
This grant awards funds made available to the Head Start program to expand HS services to 16 additional children.  This award includes $25,393.00 in start-up costs and $151,107.00 in prorated operations for the period of 9/30/09 through 9/29/20
SOUTHERN KENNEBEC CHILD DEVELOPMENT CORPORATION
Head Start promotes the school readiness of low-income children through the provision of comprehensive health, nutrition, developmental, and family services.  Arra expansion funds provides Head Start services to 20 preschool children and their
Head Start Expansion and Head Start/Early Head Start COLA and Quality, including T&TA Funds and continuation funds.  This grant supported service for low-income children in northern Kennebec and Somerset Counties in Maine.  It provides Head Sta
Highway Infrastructure Investment Grant: Areas with Population equal to or less than 200K, Rural Areas with Population under 5K
Fm E of the Spink/Clark Co Line E to the East Clark City Limits & through Henry;
I 25 - COMMERCIAL TO MAIN ? SB (STIMULUS
SR 19 FROM LAUDERDALE C.L. TO NESHOBA CL. & SR 19 FROM NEWTON CL TO SR 492
Cost of Living funds are being used to increase the rates of pay for all staff by 2.1% and are being disbursed during the twelve month period effective July 1, 2009.  Quality Improvement funds (50%) are being used to improve staff qualification
Cost of Living and Quality Improvement funds
HEAD START ARRA FUNDING PROGRAM FUNDING ENHANCES A QUALITY PROGRAM RUN ACCORDING TO  PERFORMANCE STANDARDS AWARD # 02SE0264 FOR THE PURPOSE OF COLA AND QUALITY INCREASES
ECONOMIC OPPORTUNITY COMMISSION OF NASSAU COUNTY INC
Our Full Year Head Start, serving 564 children and families, full year and full day in Nassau County, New York promotes school readiness of low-income children through the provision of comprehensive health, developmental and family services.  W
NORTHWEST NEW JERSEY COMMUNITY ACTION PROGRAM INC
FY2009 ARRA COLA/QI  This award provides ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistant with the provisions of Section 640(a)(5)of the Head Start Act for the Head Start and Early Head Start program.  Head Star
ARRA COLA and Quality Improvement funding consistent with the provisions of Section 640(a)(5) of the Head Start act.  Project Description: Chautauqua Opportunities Inc. Head Start and Early Head Start program provides home and center based serv
Tioga Opportunities, Inc. administers the Head Start program for Tioga County New York with an overall goal to bring about a greater degree of social competence and school readiness for a target population of three to five year old children, pr
Security System Installation for facility
- ARRA Cost of Living Adjustment (COLA) and Quality improvement Funding consistent with  the provisions of 640(a)(5) of the Head Start Act -  COLA funds to achieve more positive results in staff retention and Quality improvement fund to improve
ARRA funds were provided in two categories, COLA and Quality Improvement. The COLA funds provided for an increase of 1.84% for staff members.  Quality Improvement funds provided were used for staff development, equipment and classroom supplies.
MOHAWK VALLEY COMMUNITY ACTION AGENCY, INC.
ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start/Early Head Start Program.  Head Start promotes the school readiness of low-incom
ARRA Cost of Living Adjustment and Quality Improvement consistent with the provisions of of Section 640(a)(5) of the Head Start Act. The funding provides a 1.84% cost of living adjustment for head start and early head start employees.  The qual
FY 2009 Head Start and Early Head Start ARRA COLA & Quality Improvement
MANHASSET GREAT NECK ECONOMIC OPPORTUNITY COUNCIL INC
This award provides for ARRA Cost of Living Adjustment (COLA) and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act.  Head Start promotes school readiness of low-income children through the pr
Head Start COLA and Quality Improvement (ARRA). This award provides for ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start program.
Head Start  COLA and Quality Improvement (ARRA)
Head Start Quality Improvement and COLA Funding of ARRA 1.84% personnel cola increase,and to improve programmatic planning and assessment, to improve staff competencies, and to improve child curriculum and assessment.
TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
Early Head Start: Columbia University Early Head Start (CUEHS) has been operating in Northern Manhattan for over 15 years. It provides services 236 low income children and families in Northern Manhattan. CUHS serves a catchment area that includ
Reply: Award 02SH0235 1. Head Start/Early Head Start Expansion 2. This funding expands Head Start Preschool services to an additional 96 children ages 3-5 years and also expands Early Head Start services to an additional 55 children ages 0-3 ye
The award provides American Recovery and Reinvestment Act Head Start Expansion funds to serve fifty-seven children additional children. The Head Start Program provides comprehensive services for low income children and families. Head Start enha
CATTARAGUS COUNTY PROJECT HEAD START INC
This award provides for ARRA Head Start Expansion Funding consistent with the provisions of the Head Start Act for the Head Start program.  Head Start promotes the school readiness of low-income children through the provision of comprehensive h
CAYUGA/SENECA COMMUNITY ACTION AGENCY, INC.
FUNDACION PARA EL DESARROLLO DE HOGAR PROPIO INCORPORADO (F.D.H.P.)
Head Start and Early Head Start Program served 123 families with childrens zer to five years old and pregnants in centers establish in Caguas and San Lorenzo communities
Head Start and Early Head Start ARRA expansion
Traffic Improvements at Various Locations, Harding Avenue (RTE 7842) at 5th and 11th Aves
MISS 305 FROM COCKRUM TO LEWISBURG  BR NOS. 14.9, 15.2,15.3,15.6
ROYALSTON- RECLAMATION OF ATHOL RICHMOND ROAD (ROUTE 32), FROM ELM AVENUE TO THE N.H. S.L     The scope of work for the proposed project is to reconstruct Athol Richmond Road in the Town of Royalston from Elm Avenue in Royalston to the New Hamp
Royalston- Reclamation of Athol Richmond Road (Route 32), from Elm Avenue To The N.H. S.L
SOUTHBRIDGE- RECONSTRUCTION OF ROUTE 169 (WOODSTOCK ROAD) FROM THE CONNECTICUT S.L. TO ROUTE 131 (E. MAIN STREET)     This Footprint Road project involves milling and resurfacing, selected full-depth construction and minor box widening to provi
Southbridge - Footprint Road Rehab Project Rte 169(No.Woodstock Rd)  See also STP
Cambridge - Newton - Fiber optic connection at three locations (ITS)      Dist 4 via Rte 2 to MBTA Alewife station in Cambridge, Newton rest area on Rte 128 to MBTA riverside station, MEMA bunker to MTA toll plaza in Framingham.
Fiber Optic Connect 3 Loc Cambridge Rt 2-MBTA Alewife, Newton Rest Area Rt.128 to MBTA, Framingham
US 90 From Dolphin Drive to the West Pascagoula River
Bridge Deck Replacement Program Rt 440 Ramp V/Boggs St. west Side Ave. State St & NJ Transit, Desgin
SD 36, From the Junction of US16A/SD36 E 0.9 Mi
SR 18/SR 109 AND SR 74 INTERSECTION IMPROVEMENT
I-5/Port of Tacoma Rd to King County Line - Add HOV
STATE OF OHIO OFFICE OF BUDGET AND MANAGEMENT STATE ACCOUNTING
Ohio EPA was awarded a State Clean Diesel Program Grant to fund a retrofit project targeting school bus fleets in the state of Ohio. The general purpose of the grant is to reduce diesel emissions and improve air quality.
ARRA State Clean Diesel - Ohio Environmental Protection Agency
The San Diego County Air Pollution Control District was awarded a National Clean Diesel Funding Assistance Program Grant to fund the retrofit/replacement/repower project targeting diesel school buses in San Diego County.  The general purpose of
This agreement provides American Recovery and Reinvestment Act funds as an additional financial assistance source for the recipient’s efforts to assess and cleanup petroleum releases from leaking underground storage tanks (LUST) sites in Hawa
ARRA - Leaking Underground Storage Tank Program
Highway Infrastructure Investment for the Puerto Rico Highway Program.  This project consist in the Construction of Mayaguez West By-Pass by widdening PR-64 from PR-2 to El Maní, at Sabanetas and Algarrobos Wards.  This highway improvment is c
North Creek Trail - Section 1, Stage 2 (Schnitzer)
North Creek Trail - Section 2, Stage 2 (Canyon Park)
Rainier Avenue South (SR 167) Improvements Project ? Phase 1: Shattuck Avenue Stormwater Bypass
SR 570 BTW AMITE CL AND W CORP  MCCOMB & SR 570 FR .58 MI WEST OF PIKE CTY LINE TO CTY LINE
The water fund infrastructure investment in the Ohio County Development Authority of Wheeling, West Virginia is essential for opening up a business and industry development area in the Highlands area of the Northern Panhandle region. This const
The EDA investment includes assistance to fund the improvement of White Wagon Road in Chemung County. The investment will  enhance the water system and to improve the sewer system that will aid in the operations of a $96 million, 751,000 sq. ft
Off-Site Sanitary Sewer, Water and Roadway Work
FY2009 CDFI Program Award.The award provided $2,000,000 which OFN will use as capital and operating expenses for our Loan Fund.   OFN lends capital to Member CDFIs. As of FYE 2009, OFN had more than $60 million outstanding to CDFIs throughout t
Opportunity Finance Network, financial intermediary for community development financial institutions.
US 195/Hatch Rd to Jct I-90 - Dowel Bar Retrofit - NB
ACTION FOR BOSTON COMMUNITY DEVELOPMENT, INC.
ARRA Head Start Expansion.  The award provides for operational and startup monies at three locations for 48 ARRA Head Start children; ten(10) children at Madison Park complex in Roxbury, twenty(20) children at Sunnyside Child Care in Roxbury, a
ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start and Early Head Start Programs.  Head Start promotes school readiness of low-inco
Cost of Living grant is for 1.84% increase for all staff. Quality Improvement grant is for salary and fringe increases for teaching and transportation staff.  Classroom renovations, materials, and furniture will also be purchased with this gran
ARRA funding is to increase wages to staff members by 1.84% totaling $26,303 and to improve the overall quality of the Head Start Program with the remaining $66,893.
This award provides for ARRA cost of living adjustment (COLA) and quality improvement funding consistent with the provisions of section 640(a)(5) of the head start act for the head start and early head start program.  Head start promotes the sc
Head Start promotes the school readiness of low-income children through the provision of comprehensive health, nutrition, developmental, and family services. Early Head Start incorporates all of the Head Start program content areas into a compr
TRI-COUNTY COMMUNITY ACTION PROGRAM, INC
This award provides for ARRA Cost of Living Adjustment (COLA) and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start and/or Early Head Start program. Head Start promotes the
ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act., serving children in Lowell, MA.  Head Start is US program designed to help children from birth to
ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act. Head Start promotes the school low-income children through the provisions of comprehensive health,
Federal project 0200028, involving milling plant mix, placing pit run subbase, bituminous pavement surfacing, chip seal, and miscellaneous work on 13.78 miles on WYO 30, beginning at reference marker 111.80 between Basin and Burlington, in Big
Highway Infrastructure Investment Grant: Areas with Population equal to or less than 200K, Transportation Enhancements
Okoma Drive/SR215  Sidewalk Project (from 4th Ave. to Jasmine St.)
SR 35 multilane section in Kosciusko from Natchez Trace Parkway to SR 12.  Stimulus Overlay
NBL, Fm S of the Volin Exit to S of the Beresford Exit
ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act
This funding will provide economic stimulus to the nation while furthering the ACF mission to promote the school readiness of low-income children. The objective of the Head Start program is to enhance the cognitive, social and emotional develop
ARRA Cost of Living Adjustment (COLA) and Quality Improvement Funding consistent with the provisions of Section 640(a)(5)of the Head Start Act for the Head Start and/or Early Head Start program. Head Start promotes the school readiness of low-i
BROOKLYN BUREAU OF COMMUNITY SERVICE (INC)
ARRA COST OF LIVING AND QUALITY IMPROVEMENT FUNDING FOR HEAD START PROGRAM
ST LAWRENCE COUNTY COMMUNITY DEVELOPMENT PROGRAM INC
This award provides for ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start PRogram
Head Start Quality Improvement and COLA (ARRA) Program - Throughout Ocean County New Jersey, O.C.E.A.N., Inc. used the COLA and ARRA funds to increase staff salaries. The 1.84% was part of the individual salary that was supported by Head Start
ARRA Cost of Living Adjustment(COLA) and Quality Improvement Funds consistent with the provisions of Section 640(a)(5) of the Head Start Act. The Bayonne Head Start has three centers located in the City of Bayonne,N.J.with a funded enrollment o
This Head Start ARRA Cost of Living Adjustment (COLA) and Quality Improvement Funds Project is consistent with the provisions of section 640(a)(5) of the Head Start Act and will enhance the provision of high quality Head Start services provided
JERSEY CITY CHILD DEVELOPMENT CENTERS INC
Head Start Quality improvement and COLA (ARRA)to provide funding for site improvements at 93 NELSON AVENUE location, Jersey City, New Jersey. Funds were also used to provide quality training to our professional staff to implement a high quality
MASONRY RESTORATION AND SITE IMPROVEMENT
SEASONAL HEAD START & EARLY HEAD START PROGRAM DIOCESE OF MAYAGUEZ
ARRA COST OF LIVING ADJUSTMENTS & QUALITY FUNDS AWARDED FOR IMPROVING SALARIES OF STAFF, TRAINING AND MINOR REPAIRS FOR HS AND EHS CENTERS SERVING 156 CHILDREN.
ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding for our Head Start Program, consistent with the provisions of Section 640(a)(5) of the Head Start Act.
Grand Street Settlement Early Head Start provides comprehensive services to 56 low- income children ages birth to three, and pregnant women on the Lower East Side of Manhattan. These services include developmental, health and child care as well
Award Description To provide highly qualified and  continuos services to 76 infants  and toddlers (ages 0-3) and 12  pregnant woman of low income  and qualify improvements to  guarantee health and safety  matters in our Early Head Start Centers
ARRA Cost of Living Adjustment and Quality Improvement Funding for the Camden, NJ Early Head Start program serving 150 children.  Program funding provides pay increases for permanent and temporary staff and an enhanced overall quality of the Ea
Early Head Start Quality Improvement and COLA
ARRA Head Start expansion which provides Head Start home based (30 slots)and (48) center based services for a total of 78 additional Head Start children in Chautauqua County in Western New York State. These services include all educational serv
Rt 30, Pavement Rehabilitation, Atlantic County, Construction
(E. Beckley Bypass) Grey Flts. Rd. - Cranberry Cr.
FALL RIVER- FREETOWN- INTERCHANGE CONSTRUCTION ON ROUTE 24     The project includes the construction of a new interchange (Exit 8B) on Route 24 in Freetown and construction of new access roadways east to the proposed Fall River Executive Park a
Fall River- Freetown- Interchange Construction on Route 24
CONCORD- RESURFACING & RELATED WORK .     Resurface Route 2 from Walden to the Sudbury town line and from Nine Acre Corner road to Elm Street. Work includes guardrail, painting and signage.
Concord - Resurfacing and Related Work on Route 2 (Warden St. to Sudbury Rd.)
SWANSEA- RESURFACING & RELATED WORK ON ROUTE 6     Mill and resurface Route 6 from the Somerset town line to the Rehoboth town line. Work on this project also includes the repair of frost heaves and the reconstruction of existing sidewalks.
Swansea - Resurfacing and Related Work on Route 6
AVON STOUGHTON - RESURFACING & RELATED WORK ON ROUTE 24     This is a Pavement Preservation Project for Route 24 in Avon and Stoughton.
Avon-Stoughton - Resurfacing and Related Work on Route 24
HARVARD LITTLETON - RESURFACING & RELATED WORK ON ROUTE 2     Resurface Route 2 from the vicinity of the Littleton Road Bridge to the Boxborough town line, a distance of approximately 4.4 miles. Work includes minor box widening to extend existi
Harvard Littleton - Resurfacing and Related Work on Route 2
COMMUNITY ACTION COUNCIL OF HOWARD COUNTY INC
Emergecny Assistance and crisis intervention program to assist participants to acquire food from the Agency's food bank; to also assist with evictions and foreclosure prevention and to provide emergency assistance and case management.
Upper Sims Way Improvement Project - A/B
BOSTON- CAMBRIDGE- NORTH BANK BRIDGE CONSTRUCTION, B-16-302=C-01-028, RIVERWALK OVER CHARLES RIVER & MBTA     MassHighway proposes to construct the North Bank Bridge over the MBTA Commuter Rail tracks providing a bicycle/pedestrian connection f
North Bank Bridge (B-16-302 - C-1-8) River Walk - Charles River
NORTH ADAMS- RESURFACING OF VARIOUS FEDERAL-AID ROADWAYS     This project proposes to utilize pavement preservation techniques to resurface approximately 11.4 miles of various Federal-Aid eligible roadways (NHS and non-NHS) in North Adams.
North Adams- Resurfacing of Various Federal-Aid Roadways
Federal Work Study provides need-based financial aid to students.
BELLEVUE COMMUNITY COLLEGE ASSOCIATION OF HIGHER EDUCATION
CHICKASAW TRAIL INDUSTRIAL PARK ACCESS ROAD
SR 501/Ridgefield Interchange - Rebuild Interchange
Highway Infrastructure Investment Grant: Transportation Enhancements, Available for Use in Any Area (flexible)
SR-68; 6200 SOUTH / REDWOOD ROAD / I-215
US 49 beg. 15.9 mi. north of the Covington CL then run north for 5.6 mi.
US 49 beg. at the Covington CL then run north for 15.9 mi. (NB lane)
The Minnesota Pollution Control Agency (MPCA) performs water quality management planning activities that are authorized under the Clean Water Act and the American Recovery and Reinvestment Act of 2009. These activities include: 1) Updating MPCA
Fiscal Year 2009 American Recovery and Reinvestment Act - Water Quality Management Planning Grant
The goal of the Minnesota Pollution Control Agency (MPCA) Petroleum Remediation Program (PRP) is to protect human health and the environment by evaluating, minimizing, or correcting petroleum contamination impacts to soil and water caused by le
LUST American Recovery and Reinvestment Act
Jackson County Rest Areas - I-10 East & West
RECOVERY-#2147 INSTALL LEFT TURN LANES & REPAVE JEFFERSON BLVD., PHASE 1
RECOVERY-#626 INSTALL LEFT TURN LANES & REPAVE LEE BLVD.
'Highway Infrastructure Investment Grant: Urbanized Areas over 200K Population, Available for Use in Any Area (flexible)'
1R Improvements to Rte 146 and Rehabilitation of the Wilbur Road Bridge No. 415
FAIRFIELD; RT 15; FROM CONGRESS ST. TO MOREHOUSE HWY.; RESURFACING, BRIDGE, AND SAFETY IMPROVEMENTS. (NO ADDED CAPACITY) (CN)
The $1.5 million investment to Northern Enterprises funds the construction of a publicly owned and FDA-licensed food business incubator to serve entrepreneurs and provide culinary packaging resources to other local firms. The incubator will fos
Other Similar Organizations (except Business, Professional, Labor, and Political Organizations)
ARRA COLA and Quality Improvement Funds will be used to:  Increase the hours of two family workers, provide mental health services to children, provide professional development to staff to improve qualifications, increase compensation and benef
ARRA COLA adjustment, and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act.  Head Start promotes the school readiness of low-income children through the provision of complrensive health, deve
ARRA Cost of Living adjustment (COLA) and Quality Improvement Funding Consistent with the provisions of Section 640(a)(5) of the Head Start Act.
ARRA Cost of Living Adjustment(COLA),and Quality Improvemant Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act
This award provides a cost of living increase and funds to increase program quality. The expected outcome is to retain quality staff and prevent staff turnover which would aversely effect program quality and staff effectiveness. This award will
HEAD START - Cost-of-Living Adjustment increase of 1.84% in the amount of $25,102. Quality Improvement funds of $77,475.
Head Start ARRA Quality Improvement and COLA.  The Quality / COLA project was completed on September 30, 2010 and all planned aspects of this award were fully implemented .  Full implementaion included: supporting the costs of books and tuition
CHAMPLAIN VALLEY OFFICE OF ECONOMIC OPPORTUNITY, INC
The overall purpose of the Head Start Expansion grant is to expand Head Start Services in two centers by a total of 10 children.  In addition to providing Head Start services to these children, our program seeks to expand interpretive and trans
This award provides ARRA Early Head Expansion to serve 38 children.  SNHS has created a program design that will address the community need for affordable infant/toddler care; offer respite care for children at risk of abuse or neglect; and pro
Head Start & Early Head Start Expansion to serve 56 early/infant toddlers and 18 preschool Head Start children.  The Head Start and Early Head Start programs provide family-centered services and promotes the healthy development of children and
Sterling Highway Rut Repair, Soldotna to Cohoe Loop
Highway Infrastructure Investment Grant: Areas with Population equal to or less than 200K, Available for Use in Any Area (flexible)
FY2009 ARRA COLA/QI - This award provides for ARRA cost of living adjustment (COLA) and Quality Improvement Funding consistent with the provisions of Section 640(a(5) of the Head Start Act for the Head Start and/or Early Head Start program.  He
COMMUNITY PROGRAM CENTER OF LONG ISLAND INC
FY2009 ARRA COLA/QI - Awards a cost-of-living adjustment increase for Head Start employees in the amount of $27,878 and awards quality improvement funds in the amount of $60,091, together totaling $87,969.  The cost of living increase is calcul
HEAD START COMMUNITY PROGRAM OF MORRIS COUNTY INC
COLA/QI-Improve staff qualificationsa  annd assitance to staff completeing post secondarry course work. Employ a floating teacher assistant. Help defray cost of transporting children.
Office of Elementary and Secondary Education
Rt 29 West Amwell Twp Drainage, Utility Relocation
Rt 1, Vicinity of D&R Canal to North of CR 533, Resurfacing
Federal Work Study Program provides need-based financial aid to students.
I-5/North Kelso to Castle Rock - Stage 2 - Concrete Rehab
I-5/I-205 Junction to Dike Rd - Median Cable Barrier
TRANSPORTATION, NEW MEXICO DEPARTMENT OF
US 78 FROM EAST END OF THE TENN-TOM BRIDGE TO THE ALABAMA STATELINE
Queen Mary Pavement Rehabilitation & Resurfacing - Phase I
US 97/Centerville Rd to Bickleton Rd & Satus Pass
The Clean Air Branch, Dept. of Health, State of Hawaii was awarded a State Clean Diesel Program grant to fund a replacement program targeting school buses and heavy duty diesel vehicles in the state of Hawaii. The general purpose of the grant i
SR 234/GILLIONVILLE RD FROM EIGHT MILE RD TO LOCKETT STATION
US 98 from the west end of the Tylertown bypass to the east end of the Tylertown bypass
US 84 from the US 61 Intersection to the Franklin CL
US 16A, Fm the W Entrance of Custer State Park E to the Jct. With SD36,
Project is the necessary infrastructure to expand the Pittsfield Industrial Park.  The total size of the project is 28 acres comprised of 6 new lots.  The project includes construction of roadway, water mains, sewer mains, three-phase power, dr
Pittsfield Industrial Park, Phase II (Expansion)
BEN FRANKLIN TECHNOLOGY PARTNERS OF NORTH EASTERN PENNSYLVANIA
The $6M EDA investment will facilitate the four-story addition (47,000 square-foot expansion) to the Ben Franklin Tech Ventures incubator/post incubator facility located on Lehigh University's Mountaintop Campus. The site involves the revitaliz
Administration of General Economic Programs
Cost of Living Adjustment (COLA) increase of 1.84% in the amount of $182,856 for Head Start.  These funds must be obligated to pay for staff salaries over the 12 month period following the effective date of this grant wor within the 12 months a
PEOPLE ACTING IN COMMUNITY ENDEAVORS, INC.
ARRA Cost of Living Adjustment (COLA) and Quality Improvement Funding consistent with Section 604(a)(5) of the Head Start Act.
BHS Award Description: New Haven Board of Education Head Start provides comprehensive health, developmental and family services to 726 children and their families residing in the city of New Haven through a variety of program options including
Funds are used to support salaries that have had State funds cut and to support employer provided health insurance costs.  We also have used funds to replace classroom furniture and equipment. One Curriculum director to develop Literacy learnin
ARRA Salary and Health Insurance support
NORWALK ECONOMIC OPPORTUNITY NOW, INCORPORATED
This award provides for ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start program. Head Start promotes the school readiness of low
This award provides for ARRA Cost of Living Adjustment(COLA), and quality improvement funding consistent with the provisions of Section 640(a)(5) of the Head Start and Early Head Start program.  Head Start promotes the school readiness of low-i
Cost-of-Living adjustment (COLA) increase of 1.84% totaling $36,615 and Quality improvement funds totaling $89,417, for both Head Start and Early Head Start.
GREATER LAWRENCE COMMUNITY ACTION COUNCIL, INC
Project Description ARRA COLA and Quality Funds will be used to:    1.  Increase compensation through a cost of living adjustment that represents a minimum of 1.84% of the Head Start and Early Head Start portions of their salary. 2. Increase co
Project Name: ARRA Head Start and Early Head Start COLA/Quality Number of children: EHS ? 98, Head Start ? 1100 Program Options: Home-based (EHS), and both home-based and center-based (HS) Cities or Counties: Providence, Pawtucket, Central Fall
Renovate Senior Citizen Center to include a courtroom that is handicap accessible.
This request concerns infrastructure used for R&D in microwave superconductivity, both basic studies and technology development.  A central activity in these investigations is the testing of single- and multi-cell microwave cavities.  The worki
SUPPORT OF THE CORNELL ELECTRON STORAGE RING (CESR) FACILITY
SR 29 REPLACE BR 12.8 AT BLACK CREEK [BR # 12.8]
JOINT COUNCIL FOR ECONOMIC OPPORTUNITY OF CLINTON & FRANKLIN COUNTY
Joint Council for Economic Opportunities of Clinton and Franklin County, Inc.'s Head Start program serves 337 Children and their families in 12 Centers (17 Classrooms) and three Home Based options. We provide a quality Early Childhood Education
ARRA COLA and Quality Improvement Funds - Staff will receive a 1.84% temporary increase in their base pay.  Quality Improvement Funds will be used to ensure compensation is adequate to attract and retain qualified staff in order to enhance prog
The Educational Alliance (The Alliance) is using COLA funds to provide a permanent 3.06% salary increase to all full-time Federal Early Head Start and Head Start staff at all four Educational Alliance Head Start/Early Head Start sites in Downto
FY2009 ARRA COLA/QI for Head Start and Early Head Start
ARRA COLA AND Quality Improvements. WE added 1.84% salary increase to our employees. We hired an Early Education Specialist that completed onsite review of each classroom to ensure environment. We also completed a large lead abatement project a
2009 ARRA Cost of Living Adjustment (COLA)and Quality Improvement Funding consistent with the provisions of section 640(a)(5) of the Head Start  Act, as amended.
The CHCCC received two discretionary grants under the American Recovery and Reinvestment Act. The first a grant(award number (02SE029/01) totaling $42,219 included $15,764 to cover the 1.84% COLA expenses that all CHCCC HS employees will receiv
FY 2009 ARRA COLA/QI This award provides a cost of living adjustment (COLA) increase of 1.84% in the amount of $111,198 for the 131 Head Start staff. Providing school readiness service to 722 low income childrent in a center based program locat
WESTCHESTER COMMUNITY OPPORTUNITY PROGRAM, INC.
ARRA Cost of Living Adjustment (COLA) and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act. Head Start promotes the school readiness of low-income children through the provision of comprehens
Highway Infrastructure Investment Grant; Available for Use in Any Area (flexible)
Road rehabilitation and widening of Route 17
Route 17 Rehabilitation and Widening from Route 4 to Route 4A (Phase 1)
BURLINGTON LEXINGTON READING WOBURN TRAFFIC SIGN & GUIDE REPLACEMENT ON I-95 (SR 128)     Replace traffic and guide signs on Interstate 95 (Route 128) between US 3 (Exit 32) in Lexington and I-93 (Exit 37) in Reading, including applicable signa
Burlington-Lexington-Reading-Woburn - Traffic Sign & Guide Replacement on I-95 (SR 128)
EASTHAMPTON - GREENFIELD - NORTHAMPTON- SOUTHAMPTON - WESTFIELD RESURFACING AND RELATED WORK ON ROUTES 10 AND 5      Project will consist of milling the existing paved surface of Route 5 and 10 and repaving with 2 of HMA modified top course mat
Easthampton - Greenfield - Northampton- Southampton - Westfield Resurfacing and Related Work on Rout
SHREWSBURY- RESURFACING ON RTE. 20 (Re-Ad)     This project will commence at Route 140 in Shrewsbury and continue in a westerly direction to Massasoit Road in Worcester, a distance of approximately 3.5 miles.
LENOX- RECONSTRUCTION OF ROUTE 7A (KEMBLE STREET) FROM ROUTE 7 TO ROUTE 183     Reconstruction of State Highway from the Route 7 intersection north for approximately 1.25 miles to the end of the State Highway just south of the intersection with
HATFIELD- ELM STREET RECLAMATION AND RELATED WORK     The project involves roadway and sidewalk rehabilitation on town-owned Elm Street in the Town of Hatfield, and includes cold planing, roadway reclamation, hot mix asphalt paving, replacement
Hatfield- Elm Street Reclamation and Related Work
FITCHBURG- WESTMINSTER- RESURFACING & RELATED WORK ON ROUTE 2, FROM EXIT 26 (WESTMINSTER) EASTERLY TO THE JUNCTION OF ROUTE 31, EXIT 28 (FITCHBURG)     The Project limits are Route 2 in Westminster from Wyman Road/Village Inn Road (Exit 26), ea
Fitchburg- Westminster- Resurfacing & Related Work on Route 2, from Exit 26 (Westminster) Easterly T
WESTFORD - INTERSECTION AND SIGNAL IMPROVEMENTS AT ROUTE 110 (LITTLETON) AND ROUTE 225 (CONCORD RD.)     The Town of Westford is proposing to widen approximately 3,000 feet of Littleton Road (Route 110).  The existing cross section contains one
Westford - Intersection and Signal Improvements at Route 110 (Littleton) and Route 225 (Concord Rd.)
BOSTON- INTERSECTION & SIGNAL IMPROVEMENTS ON DORCHESTER AVENUE (15 LOCATIONS)     This project will make safety and mobility improvements at four major intersections along the Dorchester Avenue corridor; Andrews Square, Glover's Corner, Fields
Boston- Intersection and Signal Improvements on Dorchester Avenue (15 Locations)
NORTHAMPTON - JACKSON STREET SCHOOL SAFE ROUTES TO SCHOOL IMPROVEMENTS     The purpose of this project is to improve access to the Jackson Street School by constructing new sidewalks, constructing a new access ramp to the nearby bike path, inst
Northampton - Jackson Street School Safe Routes To School Improvements
US 45 FM JUST N OF DRYDEN RD TO THE LEE CL
Bridge Deck Replacement Program Rt 18 0ver Rt 1, Desgin
Boston - CCTV installation at signalized intersections (ITS)      The design of up to 37 CCTV at signalized intersections throughout the city of Boston.
Boston - CCTV installation at signalized intersections (ITS)
Highway Infrastructure Investment Grant: Available for use in Any Area (flexible)
I-5/Chamber Way vicinity to Harrison Ave vicinity
Fm the End of the Pavement N of the White River to S of I90 near Vivian
Funding for diesel vehicle retrofits (DOC, DOC/CCV, FOH) and vehicle replacements.
Greater Lansing Area Clean Cities Clean Diesel
The National School Transportation Association was awarded a National Clean Diesel Funding Assistance Program grant to fund the following projects: 1) Replacement of 98 school buses with new 2009 model buses in Milwaukee, Kenosha, Racine and Wa
National School Transportation Association Go Yellow, Go Green  Campaign
EPA Brownfield Assessment Grant for Hazardous Materials
COMMUNICATIONS DEVELOPMENT, OHIO DEPARTMENT OF
Brownfield Revolving Loan Fund program to facilitate hazardous substances cleanup loans and grants to eligible entities.
Brownfield Revolving Loan Fund for Hazardous Substances
BAY AREA AIR QUALITY MANAGEMENT DISTRICT
Drayage Truck Retrofit and Replacement Project at the Port of Oakland
Federal Work Study provides need-based financial aid to sutdents.
Two tasks in support of the US DOE Strategic Integrated Procurement Enterprise System (STRIPES) 1) Maintenance of Operating Environment – Recovery Act funds are for the increased STRIPES system capacity required by the $38B in Recovery Act ob
Highway Infrastructure Investment Grant: Urbanized Areas over 200K Population, Available for Use in Any Area (flexible)
SYRACUSE ROAD; 1000 WEST TO 2000 WEST, SYRACUSE
FAIRFIELD; RT 15; REPLACEMENT OF BRIDGE# 00743 OVER MILL RIVER. (NO ADDED CAPACITY) (CN)
Construction of a 32,000 sq.ft. Phase II addition to the Dartmouth Regional Technology Center (DRTC), a technology business incubator.  The DRTC offers educational and infrastructure support for programs to assist researchers and entrepreneurs
Dartmouth Regional Technology Center Phase II Addition
US 195/Steptoe to SR 271 - Rumble Strips - Centerline
WOONSOCKET HEAD START CHILD DEVELOPMENT ASSOCIATION INC
Head Start promotes the school readiness of low-income children through the provision of comprehensive health, developmental and family services.  This ARRA Cost of Living Adjustment (COLA) and Quality Improvement Funding is used for temporary
$51,028 in COLA funds to fund a 1.84% adjustment to Head Start Staff for a 12 month period. $149,659 in quality funds to enhance the Head Start program which serves 381 children across Cape Cod, the islands, and town of Wareham, Massachusetts.
Head Start Quality Improvement and COLA award.
ACTION FOR BRIDGEPORT COMMUNITY DEVELOPMENT, INC.
ARRA Cost of Living Adjustment (COLA) and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act
SOMERVILLE MENTAL HEALTH ASSOCIATION INC
ARRA Cost-of-Living Adjustment (COLA) increase of 1.84% in the amount of $16,376 and Quality Improvement funds of $38,910, consistent with the provisions of Section 640(a)(5) of the Head Start Act.
Expansion provides Expansion funded to serve  87 children. The Early Head Start program provides family-centered services for low-income families with very young children. Our program options include home based services and family child care se
Head Start Expansion. To provide Head Start comprehensive services including education, health, nutriton, mental health and social  services for 15 children in West Springfield Ma.from low income families.Childen will attend preschool four hour
HEAD START - EXPANSION. To serve 15 additional children in the West Springfield site. YEAR 1 = $96,555 operations, $1,931 T/A amd $32. 696 start up costs. YEAR 2 = $101,235 operations and $2,025 T/A.
This award provides for ARRA Head Start Expansion funded to serve 7 children.  The Head Start program provides family-centered services for low-income families with young childrento promote the healthy development of the children and families.
The American Recovery and Reinvestment Act of 2009 Head Start Expansion serves 18 low-income children participating in the Providence and Blackstone Valley Head Start program. The expansion classroom will be located in Providence, Providence Co
Head Start and Early Head Start Expansion
The Colleton Improvement Collaborative purpose is to stimulate small business development, promote entrepreneurship, and to provide Workforce and Competitive Skills Development for the underserved citizens of Colleton County. CIC will provide 4
Oswego County Opportunities, Inc. received the American Recovery and Reinvestment Act award number 02SE0053/01 for the budget period 7/1/2009 thru 9/30/2010.  This award served 248 Head Start children through part and full day center based opti
L I CHILD AND FAMILY DEVELOPMENT SERVICES INC
ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act.
Improving the overall quality of Niagara County Headstart, Inc. through increased compensation and benefits to our staff as well as improved computer technology and conditions for the families and children of our program.  ARRA Cost of Living A
Off-System Bridge Off-System - 2 Miles South & 1 Mile West of Cando
UPGRADE ROADS IN SHARKEY COUNTY-STREETS IN THE TOWN OF ANGUILLA - VARIOUS STREETS [A - V]
Wheeling - Valley Grove Rd. Approach Slabs
Fm the Slim Buttes Area to the West Jct of SD20.
Hawthorne School Bridge - Structure 016-7000
The general purpose of the grant is to reduce diesel emissions and improve air quality.  The Minnesota Pollution Control Agency (MPCA) has used the American Recovery Act Grant  (ARRA) to fund both public and private diesel emissions reduction p
American Recovery & Reinvestment Act - Clean Diesel Program Grant - Minnesota Pollution Control Agency
Ohio Department of Development was awarded a National Clean Diesel Funding Assistance Program Grant to fund a retrofit/replacement/re-power project or program targeting diesel locomotives, construction equipment, school busfleets, long haul tru
ARRA National Clean Diesel Grant Program
Child Nutrition Discretionary Grants Limited Availability - PRIVATE SCHOOL AMOUNT PROCESSED BY AGRICULTURE NSLP: To assist States, through cash grants and food donations, in making the school lunch program available to school children and to en
Child Nutrition Discretionary Grants Limited Availability
I-15 From CA/NV Stateline to Milepost 17.00 CL0.00 to CL16.35
FAS 174, County Highway 6 (Shabbona Road)
GlouCo - CR 555 Tuckahoe Road from Route 322 to Main Road in Franklin and Monroe Townships.
EDA (Grant) Water Only - 2009/2010 Recovery Act ---- Construction of a surface water treatment plant, water distribution line and a water storage tank to support the development of the Baker Industrial Park.
BERKSHIRE COUNTY HEAD START CHILD DEVELOPMENT PROGRAM, INC.
ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640 (a)(5) of the Head Start Act.
Cost-of-living adjustment (COLA) increase of 1.84% in the amount of $61,987 for Head Start and $10,152 for Early Head Start.  Quality improvement funds of $162,131 for Head Start and $25,940 for Early Head Start.
COLA increase - 69 Head Start/Early Head Start employees received a 1.84% COLA.
COMMUNITY ACTION OF THE FRANKLIN, HAMPSHIRE, AND NORTH QUABBIN REGIONS, INC.
1.  Name of Project: ARRA Cost of Living Adjustment (COLA) and Quality Improvement Funding  2.  Program Options Offered: Full Day, Full Year Center-Based; Home Based 3.  Counties Served: Franklin and Hampshire  4.  Purpose of the Head Start Pro
ARRA Cost of Living Adjustment (COLA) and Quality Improvement funding concistant with tHE Provisions ofSection 640(a)(5) of the head Start Act.   Cost-of-Living Adjustment ( COLA)Increase4 of 1.84% in the amount of $ 77,513 for head Start. Incr
ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act. Head Start promotes the school readiness of low-income children through the provision of comprehen
The Head Start program is a porgram of the United States Department of Health and Human services that provides comprehensive education, health, nutrition and parent involvement services to low-income children and their families.
This award provides for ARRA COLA and Quality Improvements funding consistent with the provisions of Section 640(a)(5) of the Head Start Act. HS Promotes school readiness of low-income children through the provision of comprehensive, health, de
This award provides for ARRA Cost of Living Adjustment (COLA) and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start and/or Early Head Start program.  Head Start promotes the
ARRA Cost of Living (COLA) and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act.
This grant awards funds for the Head Start program under the American Recovery and Reinvestment Act for continuation of Early Head Start Services to 84 infants, toddlers, and pregnant women for the September 30, 2010-September 29, 2011 budget p
Scott County Rest Areas (2) - Site Improvements - I-20 East
This project will continue to operate, develop, and improve the Cornell High Energy Synchrotron Source (CHESS). CHESS is a unique national synchrotron radiation user facility that operates parasitically on the Cornell Electron Storage Ring (CES
OPERATIONS OF CORNELL HIGH ENERGY SYNCHROTRON SOURCE (CHESS)
Northside Dr from Medgar Evers Blvd to Jackson City Limits, Maddox Rd from Hwy 18 to John R Lynch St
ADIRONDACK COMMUNITY ACTION PROGRAMS, INC.
The ARRA funds are being used to enhance technology and replacement of an otoacoustic emissions screener, assist with rental increases, along with utilitiy and transportation cost increases.  Funds will also be used to replace current applaince
The service award for Head Start and Early Head Start is to assist in the ongoing goals of ours agency. Through the ARRA Q&I and Cola grant ours childrens of 500 will be help in better training, development, supplies and other need to make thei
The ARRA award is for the cost of living allowance increase of 1.84% for the Head Start/Early Head Start Program of the Municipality of Bayamon (salaries and fringe benefits; $224,902.00 was allocated for the Head Start Program and $13,474.00 f
Head Start/Early Head Start Program and Quality Improvement
Temporary Costs of Living increased and quality improvements to serve preschool children in Aguas Buenas, Juncos, Gurabo and Caguas.
ARRA COST OF LIVING ADJUSTMENT (COLA), AND QUALITY IMPROVEMENT FUNDING CONSISTENT WITH PROVISIONS OF SECITON 640(A) OF THE HEAD START ACT.HEAD START PROMOTES THE SCHOOL READINESS OF LOW-INCOME CHILDREN THROUGH THE PROVISIONS OF COMPREHENSIVE HE
COMMISSION ON ECONOMIC OPPORTUNITY FOR THE GREATER CAPITAL REGION, INC
FY2009 ARRA/COLA/Qi. Awards a cost of living adjustment increase for Early Head Start and Head Start employees.Created 3 new postions:2 Family Advocates to meet increasing needs of families and Education Manager to focus on literacy. Also award
COMMUNITY ACTION OF ORLEANS AND GENESEE, INC.
ARRA Cost of Living (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act.  ARRA COLA and Quality Funds for Community Action of Orleans and Genesee will be used to 1. increase compensa
Tri-County Community Action Partnership is utilizing the American Recovery and Reinvestment Act Quality Improvements funds to strengthen the quality of educational services.  The FY 2009 ARRA COLA/QI award is being used to ensure compensation a
CORTLAND COUNTY COMMUNITY ACTION PROGRAM, INC.
This award icludes a Cost of Livining  (COLA) increase of 1.84% in the amount of 28,776.  All Head Start staff received an equal cost of living which included fringe allocations.   This action also awards quaility improvement funds of $75,586 f
FY 2009 ARRA COLA AND QUALITY IMPROVEMENT / COLA FOR  SALARIES TO EMPLOYEES AND RENOVATIONS TO PRESCHOOL CENTER NAMED MI PEQUEÑO MUNDO AND 4 PLAYGROUND RENOVATIONS, TRAININGS FOR EMPLOYEES AND BUY PLAYGROUNG EQUIPMENT
To provide educational services to 135 preschool children and their families in Municipality of Adjuntas FY2009 ARRACOLA-QI and Buildings Improvement
HEAD START OF EASTERN ORANGE COUNTY, INC.
NORTHSIDE CENTER FOR CHILD DEVELOPMENT, INC.
This grant awards a cost of living adjustment (COLA-ARRA) increase for Head Start and Early Head Start staff.  In addition, this award provides quality improvement funds to enhance services in EHS and HS programs.    All ARRA funds are availabl
Northside Center for Child Development-Head Start
The award provides for ARRA Cost of Living Adjustment (COLA) of 1.84% for Head Start staff as well as Quality Improvement Funding consistent with the provisions of Section 640(1)(5) of the Head Start Act for the Head Start program.  Head Start
BERGEN COUNTY COMMUNITY ACTION PROGRAM INC
HEAD START AMERICAN RECOVERY REINVESTMENT ACT EXPANSION & EARLY HEAD START TO EXPAND EARLY HEAD START SERVICES TO SEVENTY TWO(72)INFANTS, TODDLERS, AND PREGNANT WOMEN AND TO EXPAND HEAD START WITH ADDITIONAL 40 KIDS.
This award provides for ARRA Head Start and Early Head Start Expansion funds to serve 34 preschool children and 78 infants and toddlers (pre-birth to 3 years). Head Start promotes the school readiness of low-income children through the provisio
This project generally consists of the design for and rehabilitation of Runway 13-31 at Palm Beach International Airport (PBI), including a 2-inch average depth asphalt milling, a nominal 2 inch bituminous overlay, bituminous pavement crack rep
Rehabilitate Runway [Rehab Runway 13/31] - 13/31
Bridge Deck Replacement Program                                               Route 72, Manahawkin Bay Bridge Deck Rehabilitation, Construction
BARRE- RESURFACING AND RELATED WORK, ROUTE 122 (WEST STREET) AND ROUTE 62     Resurface Route 122 and a section of Rte 62. The state highway section of the project begins just west of Pleasant Street (milemarker 48.265) and proceeds westerly to
Barre- Resurfacing and Related Work, Route 122 (West Street) and Route 62
BARNSTABLE- RESURFACING AND RELATED WORK ON ROUTE 6A     Perform resurfacing and related work on the state-owned sections of Route 6A, from milemarker 8.12 to milemarker 16.56, a distance of approximately 8.5 miles.  Also included in the projec
Barnstable- Resurfacing and Related Work on Route 6A
NORTHFIELD SCENIC BYWAY CONSTRUCTION ON ROUTE 10/63 (PHASE I)     The focus of the Northfield Street Improvement Project is to reconstruct sidewalks on Main Street and Parker Avenue in Northfield from a point north of the intersection with Rive
Northfield Scenic Byway Construction on Route 10-63 (Phase I)
BELCHERTOWN - WARE, RESURFACING AND RELATED WORK ON 2 SECTIONS OF ROUTE 9     The purpose of this project is to resurface portions of Route 9. Work will also include repairs/upgrades to guardrail end treatments  as needed and new pavement marki
Belchertown - Ware, Resurfacing and Related Work on 2 Sections of Route 9
NEWBURYPORT- PARK & RIDE EXPANSION     The proposed expansion of the Newburyport Park & Ride facility will add 105 parking spaces. Work will include the construction of a soil nail retaining wall, upgrades to the existing lighting, as well as n
Newburyport - Expansion of Park and Ride
OAK BLUFFS TERMINAL, HYANNIS TERMINAL & WOODS HOLE CENTER DOLPHINS - FERRY BOAT  RECONSTRUCTION/IMPROVEMENTS
OLD HWY 49  (A.K.A.)  CRUGER-OAK GROVE RD. - TCHULA ROAD
Boston - video systems upgrade sip Based virtual matrix switch (ITS) matrix switch.      Upgrade of the TOC and BTD video systems to IP based virtual matrix switching system.
Boston - video systems upgrade sip Based virtual matrix switch (ITS) matrix switch.
Boston - Communication equipment installation at 5 locations (ITS) & Fiber optic connection within existing conduit 3 locations      The design of communication equipment at five locations to increase bandwidth and allow for single CCTV connect
Boston - Communication equipment installation at 5 locations (ITS) & Fiber optic connection within e
I-5/Martin Way to 48th St Dowel Bar/Panel Replacement
US 49 IN YAZOO COUNTY FROM THE BIG BLACK RIVER TO THE CONCRETE SECTION AT BENTONIA
ASHFORD; RTE 89; REHABILITATION OF BR# 01256 OVER MT HOPE RIVER (CN).
Rte. 9 and Briarcliff Parkway Interchange, Platte
The City of Chicago Department of Environment was awarded a National Clean Diesel Funding Assistance Program Grant to fund a retrofit and replacement project in the City of Chicago's fleet.  The general purpose of the grant is to reduce diesel
National Clean Diesel Funding Assistance Program
To conduct petroleum substances cleanup at the former Pete's Sunoco property
To establish a City-Wide Brownfields Revolving Loan Fund Program for South Bend, Indiana.
City-Wide Brownfield Cleanup Revolving Loan Fund
The Port of Long Beach was awarded a National Clean Diesel Funding Assistance Program Grant to fund retrofit, replacement and repower projects targeting cargo-handling equipment and harbor crafts on behalf of five terminal operators within the
Diesel Emission Reduction Projects for Port of Long Beach and Tenants
This award provides stimulus funding to the City of Rio Dell for assessment of wide spread known contaminants at the former Eel River Saw Mills Site. During the life of the project, the grant recipient will conduct a site specific prioritizatio
Brownfields Assessment Project Former Eel River Saw Mill Site
COMMONWEALTH OF THE NORTHERN MARIANA ISLANDS
This project supports water quality management planning activities that are authorized under the Clean Water Act (CWA) and American Recovery and Reinvestment Act of 2009.  The goal of this project is to document the existing and possible future
ARRA - Water Quality Management Planning Section 604(b)
To renovate offices of Clay County Partnership Chamber of Commerce
HOUSING AUTHORITY OF THE CITY OF ANDERSON
I-10; East Benson Interchange to Johnson Rd
US 82 FROM NEAR MILITARY RD TO THE ALABAMA STATE LINE
TRUMBULL; RT 15; FROM MOREHOUSE HWY TO RT 8; RESURFACING, BRIDGE, AND SAFETY IMPROVEMENTS. (NO ADDED CAPACITY) (CN)
The project entails construction of a new internal circulation road and overpass over a major road and rail line on new right-of-way within the Quonset Business Park. The Park currently has 168 tenants employing over 8,800 people from southeast
Communities United, Inc. (CUI) is a Head Start and Early Head Start grantee. Award 01SE1002/01 was granted to CUI pursuant to Program Instruction ACF-PI-HS-09-06, and provides funding for Cost-of-Living Adjustments and Quality Improvement. Gran
HUMAN RESOURCES AGENCY OF NEW BRITAIN, INC.
ARRA Cost of Living Adjustment (COLA) and Quality Improvement Funding consistent with the provisions of Section 640(a)5 of the Head Start Act.
ARRA COLA and Quality Improvement funding consistent with the provisions of Section 640(a)(5) of the Head Start Act.
ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)
COMMUNITY ACTION PROGRAM-INTER CITY, INCORPORATED
ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640 (a)
HEAD START QUALITY IMPROVEMENT AND COLA (ARRA)
1.Name of Project:?Head Start/Early Head Start Staff Compensation/Program Enhancement Initiative?  2. Number of children to be served: 330 3. Program Options offered:  Head Start ? Center-Based; EHS ? Center and Home-Based  4. Cities or countie
ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for Early Head Start.  Funds also provide for the hiring of a part-time Fatherhood Initiative Facil
CONNECTICUT INSTITUTE FOR COMMUNITIES, INC.
Head Start ARRA - Head Start of Northern Fairfield County CT. (serving the municipalities of Bethel, Brookfield, Danbury, New Fairfield, Newtown, Redding, Ridgefield and Sherman) to provide COLA's to existing Head Start (center-based early chil
This award provides for ARRA Head Start Expansion funds to serve an additional 17 children, consistent with the provisions of Ssection 640(a)(5) of the Head Start Act for the Head Start and/or Early Head Start program. Head Start promotes the s
Kodiak: Rezanof Drive Rut Repair, Airport to Marine Way
This award provides for ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the DCIU Head Start Program. Head Start promotes the school readiness o
Head Start 2009 ARRA COLA/Quality Improvement Funding
Head Start 2009 ARRA COLA Quality Improvement Funding
ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act. Lancaster-Lebanon IU13, Lebanon County Head Start is dedicated to meeting the early learning needs
HUNTINGDON COUNTY CHILD AND ADULT DEVELOPMENT CORPORATION
This award provides for ARRA Cost of Living Adjustment (COLA) and Quality Improvement Funding consistent with the provisions of Section 640(a)(5)  of the Head Start Act for the Head Start and Early Head Start Programs.  Head Start promotes the
Head Start service to 219 children.Provide pay increases for all staff, add on employee and increase the hours worked for two part time employees, purchase a vehicle for program use and update the agency strategic plan and provide training for
This action awards a cost of living adjustment (COLA) increase of 1.84% in the amount of $78,892 for Head Start.  These funds must be obligated to pay for staff salaries over the 12 month period following the effective date of this grant or wit
HEAD START 2009 ARRA COLA QUALITY IMPROVEMENT FUNDING
Head Start 2009 ARRA COLA and Quality Improvement Funds: ARRA provided funding for Cost of Living Adjustments (COLA) and Quality Improvement (QI) for Head Start and Early Head Start to pay for higher operating costs, increase staff salaries and
Head Start 2009 ARRA COLA and Quality Improvement Funds
The overall purpose was twofold: 1) To award a cost-of-living adjustment (COLA) increase for Head Start employees and 2) For quality improvement.          The COLA increase is effective from July 1, 2009 through June 30, 2010.  The Quality Impr
Head Start (children 3-4) and Early Head Start (children 0 -3) are programs for low-income families providing comprehensive child care services. These include developmentally appropriate education, mental health, disabilities referrals, family
This award is for quality improvement funds for Head Start and Early Head Start and cost of living adjustment of 1.84%.These funds are obligated to pay for staff salaries and benefits over 12 month period.
COALFILC COMMUNITY ACTION PARTNERSHIP, INC
This award provides for ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start program.  Head Start promotes the school readiness of lo
Head Start 2009 ARRA COLA Quality Improvement
Project  Objectives  To provide hourly rate increases to 135 current permanent staff, from COLA and ARRA based on data from the recent salary study.  The 12 Head Start Supplemental Assistance staff will also receive the hourly rate increases th
cost of living adjustment for headstart and quality improvement
Headstart 2009 ARRA Cola and Quality Improvement
Child Development Inc Progam Improvement Funds - ARRA Cost of living adjustment (COLA) and Quality Improvement consistent with the provisions of section 640(a)(5)of the Head Start Act.  A temporary wage/salary adjustment of 1.8% was awarded to
2880 Pottsville-Minersville Hwy  Suite 210
Head Start Program & American Recovery & Reinvestment Act (ARRA) [COLA and Quality Improvement] to provide child development services to 648 low-income children and their families with a center-based program in Montgomery County, MD to promote
This award provides for ARRA Cost of Living Adjustment (COLA) and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start and/or Early Head Start program.  Our program used the He
ARRA COLA Quality Improvement Funding for 2009 Head start and EHS programs to improve teacher salaries/benefits and qualifications; provide classroom equipment and supplies; and improve family literacy for EHS.
One-time COLA award for salary, fringe benefits, supplies, and playground improvements.  One 22 passenger bus with wheel chair lift, contractual training and technical assistance to improve outcome scores and increase parent involvement, and ad
The grant funded by the Recovery Act awards a cost of living adjustment (COLA) increase of 1.84% for Head Start to pay for staff salaries over the 12 month period following the effective date of the grant.  It also includes quality improvement
Award Title:  Head Start ARRA COLA Quality Improvement Training.The Grantee, University of Pittsburgh Office of Child Development (OCD), was awarded Quality Improvement funds of $91,871  More than 50% of these funds will improve staff qualifica
This award funds a cost of living adjustment (COLA) of 1.84% and additional salary enhancement for all EHS personnel and building improvements to support Center-based activities to EHS eligible children.
This award provided for ARRA Cost of living adjustment (COLA) increase of 1.84% for Early Head Start program staff and quality improvement funds for the Early Head Start program consistent with the provisions of sections 640(a)(5) of teh Head S
DHHS NEW DIRECTIONS EARLY HEAD START YEAR 13
PathStone Carbon County Head Start proposes to use the ARRA funds awarded for both COLA and Quality Improvement aspects of the program. The use of the ARRA COLA funds will center on the provisioning of an additional 1.84% to all Federal Head St
Head Start 2009 ARRA COLA Quality Improvement Funding  The ARRA award provided a curriculum training for (20) EHS Staff (including home visiting staff, health educators, family service liaisons, center base liaison).   To increase knowledge and
ARRA HEADSTART EXPANSION This award will bring Head Start services to a section of the city that has a number of pre-school age children but no pre-school services within a reasonable distance of their homes. The first(155,550 funding provided
This award provides for ARRA Head Start Expansion funded to serve 16 children. The Head Start program provides family centered school readiness services for low income families with preschool aged children (three and four years old). The ARRA H
LYCOMING-CLINTON COUNTIES COMMISSION FOR COMMUNITY ACTION INC
Head Start Expansion: This award provides for ARRA Head Start Expansion funds to increase the number of pre-school age children served in Head Start by 32 children.
Expansion of Head Start services to 15 additional children through a center-based full year/part day option.  Four and five year-old children with low school readiness scores, foster children, and homeless families will be given a priority.
ARRA COST OF LIVING ADJUSTMENT (COLA) AND QUALITY IMPROVEMENT FUNDING CONSISTENT WITH PROVISION OF SECTION 640(a)(5)OF HEAD START ACT FOR THE HS AND EHS PROGRAM.HS PROMOTES THE SCHOOL READINESS OF LOW-INCOME CHILDREN THROUGH PROVISION OF COMPRE
To renovate an additional 15, 000 sq ft of our EmergeMemphis incubator/accelerator to accommodate an additional 12-14 early stage companies, high-growth start-ups and entrepreneurs and to better fulfill our mission of enhancing viability of hig
Administrative Management and General Management Consulting Services
GOODWILL INDUSTRIES OF MIDDLE GEORGIA, INC.
The award is a $1.7M grant to acquire and rehabilitate a 29,980 square foot existing retail shopping center and convert it into the Goodwill Career Campus.
Puupeelua Avenue Resurfacing, Maunaloa Hwy to Farrington Ave and Farrington Avenue Resurfacing, Puupeelua Ave to Kalae Hwy
ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head start Act.
(1)The agency shall provide a 2.88% Cost of Living Adjustment in salaries and increase fringe benefits to 157 employees over a 12 month period.  The agency is also extending group insurance coverage to 22 employees. (2) The agency will also hi
Head Start ARRA COLA/Quality Improvement
This award provides for ARRA Cost of Living Adjustment (COLA) and Quality Improvement consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start and Early Head Start programs.  Both Head Start and Early Head St
SOUTH CENTRAL HUMAN RESOURCE AGENCY, INC.
The Early Head Start ARRA Quality Funds will be utilized to provide five additional staff training days, salary increases for staff who have degrees or will be obtaining degrees, shade structures, playground equipment, and education supplies.
Head Start 2009 ARRA Cola Quality Improvement Funding
ARRA Cost Of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act. 1. Provide a 1.84% COLA for staff paid over the grant period. 2. To provide a one time education i
1)Title: ARRA Cost of living adjustment (COLA), and Quality Improvement Funding consistent with the provision of Section 640(a).   2)Number of children to be served: There were 390 slots for Head Start children and 32 slots for Early Head Start
SUWANNEE VALLEY COMMUNITY COORDINATED CHILD CARE INC
ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act. Serving 494 Head Start and Early Head Start children and families in 10 centers located in Columbi
ARRA Cost of Living Adjustment(COLA) and Quality improvement funds
This award provides for ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start and Early Head Start programs. Head Start promotes the s
This award provides for ARRA Cost of Living Adjustment (COLA) & Quality Improvement Funding (QI) consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start program. Head Start promotes the school readiness of l
Head Start 2009 ARRA COLA Quility Improvement Funding
The award provided ARRA COLA and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act.  Head Start promotes school readiness for low income children through the provision of comprehensive health
BELL-WHITLEY COMMUNITY ACTION AGENCY, INCORPORATED
This award provides for ARRA Cost of Living Adjustment (COLA) and Quality Improvement Funding to promote Head Start's objective of school readiness of low-income children by providing comprehensive health, developmental and family services.
HS/EHS ARRA COLA & Quality Improvement funding
Head Start 2009 ARRA COLA Quality/Improvement Funding
UPPER EAST TENNESSEE HUMAN DEVELOPMENT AGENCY
ARRA COLA funds were requested to: (1) increase all Head Start employees' wages by 1.84% for the period 07/01/09 through 06/30/10.  Costs include (1) actual hourly wage increases and acompanying benefits for all Head Start staff, and (2) upgrad
This award provides for ARRA Cost of Living Adjustment(COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start and/or Early Head Start Program.  Head Start promotes the
DARLINGTON COUNTY COMMUNITY ACTION AGENCY
Project Name: Quality Improvement & COLA Chlldren Served - 428 pre-school, ages 3-4 yrs. old Program Option Offered - Center - Based Cities/Counties Served - Darlington County Program Purpose: The Darl. Cty. CAA, Inc. Head Start Program promote
NORTHWEST TENNESSEE ECONOMIC DEVELOPMENT COUNCIL
ARRA Cost of living adjustment (COLA)included for all Head Start and Early Head Start employees. Quality Improvements that are consistent with the provision of Section 640 (a)(5) of the Performance Standards.
COMMUNITY ACTION PARTNERSHIP OF NORTH ALABAMA, INC.
Head Start 2009 ARRA Program Improvement Funding - The Community Action Partnership of North Alabama's Head Start Program serves 1,779 Children and families in 12 North Alabama Counties stretching from the Mississippi line to the Georgia line.
This award provided for ARRA Cost of Living Adjustment(COLA), and Quality Improvement funding consistent with the provisions of Section 640(a) (5) of the Head Start Act for the Head Start and/or Early Head Start program.  Head Start promotes th
Adjustment (COLA),and Quality Improvement Funding consistent witht he provisions of Section 640(a)(5)of the Head Start Act
Head Start 2009 ARRA COLA Quality Improvement Funding.
Cost of living raise for Head Start Personnel.  Hire a certified nurse assistant.  Purchase 1 new car, assist with college tuition for employees, perform maintenance on Head Start Facilites.
COMMUNITY SERVICE PROGRAMS OF WEST ALABAMA, INC.
Cost of Living Adjustment (COLA) and Quality Improvement for 04SE3409  Community Service Programs of West Alabama, Inc. - Head Start Early Head Start provides high quality comprehensive services to 887 low income preschool children and their fa
AJFC Head Start/Early Head Start offers center based services to 986 low income children ages zero to five. The goal of our program is to promote school readiness by providing comprehensive health, developmental and family services.   Head Star
Head Start 2009 ARRA COLA Quality Improvement Funds
Head Start Quality Improvement and COLA (ARRA) Grant, consistent with the provisions of Section (a)(5). QI provided upgrades to the playground and kitchen equipment to four centers. Four additional centers installed security and monitoring equi
The Quality Improvement Award will be utilized to recruit and retain highly qualified Head Start Teachers, Teacher Assistants, and Family Service Advocates by increasing the base salary of staff and positions based on educational attainment. Fu
Head Start 2009 ARRA COLA Quality Improvement Funding - The funding was used to establish an extended day enrichment program for preschool children and their families at five locations in Gainesville, Florida. 286 children from 273 families par
The Head Start Quality Improvement and Cola (ARRA) award is for the funds consistent with the provisions of Section 640(a) (5) of the Head Start Act for Early Head Start program.  The Early Head Start program is family-centered and community-ba
CHAPEL HILL TRAINING-OUTREACH PROJECT, INC.
ARRA Cost of Living Adjustment (COLA) for Head Start and Early Head Start paid for staff salaries and fringe; Quality Improvement Funding consiten with the provisions of Section 640 (a) (5) of the Head Start Act.
Head Start promotes the school readiness of low-income children through the provision of comprehensive health, developmental and family services. First Steps Early Head Start provides quality childcare, family services and parenting to families
ARRA Head Start Expansion to open three additional Head Start preschool classrooms in Volusia County, Florida so that fifty-one additional low-income three and four-year-old children may receive comprehensive health, developmental and family se
ARRA Expansion added services for 36 Head Start eligible three- and four-year-olds in center-based care in Rutherford County, NC licensed child care facilities.  Head Start promotes the school readiness of low-income children through the provis
The goal of ARRA expansion is to increase services in areas where a high need has been identified through the community assessment and economic trends.  ARRA funds have allowed us to serve a total of 102 more children and families in Bedford an
To provide Head Start services to those children that need to be served in Bedford County
Received funding to expand our Head Start program to include 31 additional children in Iredell County, NC in a center based setting. These funds have been used to continue a center in Troutman and increase the size of our current classrooms, wh
Expansion of Head Start program to serve an additional 53 children in 3 classrooms. Head Start provides comprehensive services and promotes school readiness for prekindergarten children from low-income families.
BEAUFORT JASPER ECONOMIC OPPORTUNITY COMMISSION INC
HEAD START EXPANSION (ARRA) FISCAL YEAR 2009-2010. HEAD START EXPANSION SERVES 34 PRESCHOOL AGE CHILDREN IN BEAUFORT COUNTY FROM LOW-INCOME FAMILIES. THE PROGRAM PROVIDES FREE CHILD CARE/EARLY CHILDHOOD EDUCATION FROM 7:45AM - 3:30PM, MONDAY-FR
The funds from the ARRA Head Start expansion were used to enroll 36 additional Head Start children in Carrollton, Georgia; Carroll County and in Greenville, Georgia; Meriwether County. The funds were used to hire 2 qualified teachers and 2 teac
The Piedmont Community Action (PCA) Head Start Expansion Award will be used to increase the number of Head Start children enrolled in Cherokee County twenty  (20) students.  Two (2) jobs will be created to include a Head Start teacher and Head
GULFPORT BILOXI REGIONALL AIRPORT AUTHORITY( INC)
Overlay and groove Runway 18/36 (4,935' x 150')
US36 & Broadway Intersection Signalizati
Quality Improvement funds were awarded for staff to attend interpreter training, for the pay of substitute teachers for the child development center, for increased hours of the Mental Health Consultant, and for increased hours of the organizati
7th Street: Ellen Ave to North City Limits
Head Start promotes the school readiness of low-income children through the provision of comprehensive health, developmental and family services.  Head Start 2009 ARRA & Quality Improvement-funding was used to extend the hours of three classroo
ARRA COST OF LIVING ADJUSTMENT (COLA) AND QUALITY IMPROVEMENT CONSISTENT WITH PROVISIONS OF SECTION (5) OF THE HEAD START ACT
ALLEGANY COUNTY HUMAN RESOURCES DEVELOPMENT COMMISSION, INC.
Head Start 2009 COLA and Quality Improvement Funding.  The COLA was to award 1.8% salary and wage increase for all existing employees for a period of 12 months.  The amount of this award was $42,810.00.  Quality Improvement money in the amount
Head Start 2009/10 ARRA COLA & Quality Improvement  Grant is to improve staff qualifications as specified under the HS School Readiness Act; improve qualifications & skills to teach & provide services to children with disabilities; extend the a
$ 85,864 total COLA allocation awarded: 1) $53,621 ($35,702 salary and $2,727 FICA) to be used as a permanent 3.06% increase in FY 2009-10 program year for all Head Start funded staff positions. $32,243 total ARRA allocation awarded: 1) $32,243
Title: ARRA Cost of Living Adjustment (COLA) and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act.  York County Head start develops partnerships that promote quality opportunities for childre
ARRA funding for Head Start and Early Head Start Service Programs to serve three hundred children and families in Wyoming County, West Virginia utilizing a variety of program options designed to meet family needs.
Early Head Start cost of living increase of 1.84% in the amount of $11,832 and quality improvement funds of $40,532.  This funding is consistent with the provisions of section 640(a)(5) of the Head Start Act for the Early Head program.  The Eal
The Head Start ARRA Expansion award is used to assist four year old children and their families with the transition of entering Kindergarten the following fall in one of Prince William County's Public Schools.
This Head Start ARRA Expansion award provides for funding to serve 36 additional four-year-old children.  36 were enrolled from January 4, 2010 until June and those students entered kindergarten in September.  Another 36 four-year-olds are curr
BOARD OF EDUCATION OF PRINCE GEORGE COUNTY, MD, INC
This award titled 'ARRA Headstart Expansion' is funded to serve 60 additional Head Start children.  The Head Start program provides family-centered services for low-income families with children 3 and 4 years old.  The targeted areas for this a
Construction of water and sewer for the Keystone project. Construction of access road bridge. Add the wear surface to the upgraded road.
Construction of water and sewer for the Keystone project
The project involves the renovation of a former furniture manufacturing facility and its conversion into a one-stop workforce development center (the WIN Manufacturing Solutions Center).
Itawamba Community College: WIN Manufacturing Solutions Center
Infrastructure grant to construct rail to the Enterprise South Industrial Park in Hamilton County, Tennessee.
The project's purpose is to preserve and create jobs and promote economic recovery.  The project scope entails the expansion of the Horse Cave Wastewater Treatment Plant.  The facility is near capacity making new industry location and current i
Horse Cave Wastewater Treatment Plant Expansion
MT SAN ANTONIO COMMUNITY COLLEGE DISTRICT
Federal Work-Study provides need-based financial aid to students
BETHLEHEM CENTER OF CHARLOTTE, INC., THE
Headstart 2009 ARRA COLA Quality Improvement Funding.
This award provides for ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start and/or Early Head Start Program.  Head Start promotes th
This award provides for ARRA Cost of Living Adjustment (COLA) and Qaulity Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start and/or Early Head Start program. Head Start promotes the
RESURGENT EDUCATION AND COMMUNITY HEALTH SERVICE, INC.
This award provides REACH Services, Inc.-Fayette County Head Start ARRA increase in funding consistent with the Head Start Act Section 640(a)(5)for the following;(1)COLA-$17,961;(2) Quality Improvement-$60,846.Head Start is a comprehensive, ear
ARRA expansion to increase cost of living for Head Staff employees and provide adequate support for necessary fringe benefits. Quality improvement award enabled the agency to improve older facilities to meet licensing and federal standards. Fun
KNOXVILLEKNOX COUNTY COMMUNITY ACTION COMMITTEE
Head Start 2009 ARRA COLA and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act Funds to be used for COLA salary increases, salary upgrades for ECE level completed, additional work for employe
ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640 (a)(5) of the Head Start Act.  ARRA COLA-Portion of fringe benefits and indirect cost of increase in compensation and portion o
ARRA COLA and Quality funds will be used to: To provide center based services to 185 Head Start and 32 Early Head Start children and families in a rural area.    To provide Quality Improvement consistent with the provisions of Section 640(a)(5)
BLUE GRASS COMMUNITY ACTION PARTNERSHIP, INC
Preschool Head Start program that will use stimulus money to provide high quality services to 303 children by hiring additional staff to work with the children and families.
`The Head Start program provides comprehensive child development services to economically disadvantaged children and families, with a special focus on helping preschoolers develp the early reading and math skills they need to be successful in s
ECONOMIC OPPORTUNITY COUNCIL OF INDIAN RIVER COUNTY INC
This award provides for ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provision of Section 640(a)(5) of the Head Start Act for Head Start Programs.  Our Head Start child development program helps to
The funding for this grant awards a cost of living adjustment increase of 1.84% in the amount of $124,782 for Head Start staff and $9,156 for Early Head Start staff. This funding also awards quality improvement funds of $443,687 for our Head St
COLLIER COUNTY, FLORIDA, SCHOOL DISTRICT OF
These ARRA funds are for COLA and Quality Improvement.  The funding is to be used for the following: .5 Inclusion Coach Professional Development Cost of Living Increases for Head Start Staff Zula Materials PreK Transportation
AIKEN/BARNWELL COUNTIES COMMUNITY ACTION AGENCY, INC.
Head Start COLA ARRA - Cost of Living Adjustment, and Quality Improvement funding
FIVE COUNTY CHILD DEVELOPMENT PROGRAM INC
Head Start 2009 ARRA COLA, Quality Improvement funding consistent with the provisions of Section 640(a)(5) of the Head Start Act:  Cola 1.84% Activities: The agency shall provide each employee a Cost of Living Adjustment of 1.00% in salaries an
Head Start 2009 ARRA Cola, Quality Improvement Funding
CLAYTON COUNTY COMMUNITY SERVICE AUTHORITY INC
ARRA Cost of living  Adjustment (COLA) and quality improvement  Funding in consitent  with the provisions of Section 640(a)(5) of the Head Start Act.
ARRA Cost of Living Adjustment(COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act
Grant funds will be used to provide cost-of -living adjustment increase of 1.84% in the amount of 102,417 for Head Start and $30,685 for Early Head Start staff.  These funds will be used for staff salaries, fringe, or increase operating  costs.
Head Start 2009 ARRA / COLA /Quality Improvement Funding
ARRA Cost of Living (COLA), and Quality Improvement funding consistent with the provisions of Section 640(a)(5) of the Head Start Act - These funds will affect the 2498 children/pregnant women enrolled in Ninth District Opportunity's Head Start
The award provides for COLA increase of 1.84% including salaries,fringe benefits and operational costs; Quality improvement funds for Head Start to include improving staff qualifications through professional development, minor building maintena
ARRA - FAA Head Start / Early Head Start 2009 ARRA-COLA / Quality Improvement Funding: EHS -Can # G04R025 - $ 56,135 HS -Can # G04R022 - $ 890,604
ARRA - COLA and Quality Improvement Funds
ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640 (a)(5) of the Head Start Act.This Grant provides funding for a cost of living increase for the staff in the Picayune School Dis
To improve the quality of our Early and Regional Head Start programs through the improvement of qualifications of educational personnel to teach and provide service to children.  Replacement of classroom/playground materials and equipment ot as
HS 2009 ARRA Cola and Quality Improvement
Head Start Quality Improvement and COLA (ARRA) We provide comprehensive health, education and family services for 176 center base children and 42 pregnant women in Leon, Jefferson and Madison counties.
Head Start 2009 COLA and Quality Improvement Funding.The award was used to increase staff salaries and benefits, offer professional development opportunities for teachers and home visitors through tuition reimbursement for school, CDA renewals
ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a) to be used to support increases in salary and benefits, and increase direct supports to 942 Head Start children and families
Head Start Expansion funding is used to pay for salaries, fringe benefits, transportation, start up supplies and equipment for eligible low-income children and families residing in Louisville, Jefferson County, Kentucky.  Funding provided oppor
CUMBERLAND COMMUNITY ACTION PROGRAM, INC.
ARRA Head Start Expansion  Provide high quality serves to 68 three year old children and their families in Cumberland County, NC.  These children will be served in a center-based setting.  The purpose of Head Start is to provide children of low
SUNBELT HUMAN ADVANCEMENT RESOURCES, INC.
The ARRA Head Start Expansion Program provided quality comprehensive services to 100 children.  The program implemented a center-based option. This program option allowed classes to operated five days per week, Monday thru Friday, from 7:30 a.
The objective of the Head Start Expansion award was to open five classrooms and to provide highly qualified staff to support the program.  Four classrooms ertr oprnrf in FY09 and continue to be fully operational.  Additionally, a fifth classroo
Headstart Expansion to serve 68 additional three and four year old students.
After two successful years of operation, the YMCA/ECDC Head Start (ARRA) continues to offer Head Start services in Atlanta/Fulton County Georgia to 100 three and four year olds and their families in a center based partnership full year, full da
Centers for Medicare & Medicaid Services
HEALTH & MENTAL HYGIENE, MARYLAND DEPARTMENT OF
This initiative will significantly expand the awareness of proper infection control technique among ASCs and SA, increase the extent to which infection control deficiencies are both identified and remedied, and prevent future serious infections
THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK INC
After a year-long absence from the U.S. Ocean Bottom Seismometer Instrument Pool (OBSIP), Lamont-Doherty Earth Observatory will rejoin OBSIP with new management, a service-oriented model, a renewed testing and verification program, and improvem
Operation and Management of the LDEO Instrument Center of the National Ocean Seismometer Pool
I-55 Rest Area in Holmes County-Site Improvements
The project will consist of renovating a vacant manufacturing plant in downtown Springfield, MO, into a structure that will include space for manufacturing, an incubator, lab and instruction space for technology and construction management depa
IDEA Commons - Entrepreneurship and Business Development Center
Pearl River Welcome Center Site Improvements - I-59
COMMUNITY ACTION AGENCY OF SOUTH CENTRAL MICHIGAN, THE
This award provides for ARRA Cost of Living Adjustment (COLA) for Head Start and Early Head Start employees. These grants promote school readiness of low-income children through the prvision of comprehensive health, developmental and family ser
AWARD TITLE: HEAD START FULL YEAR PART DAY HADDICAPPED TRAINING AND TECHNICAL ASSISTANCE.DESCRIPTION: ARRA Cost of Living adjustment (COLA), and Quality Improvement Funding consistnent with the provisions of Section 640 (a) (5) of the HeadStart
CAPITAL AREA COMMUNITY SERVICES, INCORPORATED
This award provides for ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start and Early Head Start programs.  Head Start promotes the
Head Start:Full Year Part Day Handicapped Training &Technical Assistance
This award provides for ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start and Early Head Start program.  Head Start promotes the s
Head Start: Full Year Part Day Handicapped Training and Technical Assistance
ANOKA COUNTY COMMUNITY ACTION PROGRAM, INC.
Awarded funds were made available to provide a cost -of-living increase of 1.84% for a 12 month period. Program improvement funds were also awarded to increase program operation weeks, extend staff employment, increase staff compensation and be
WESTERN INDIANA COMMUNITY ACTION AGENCY, INC.
This award provides for ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section (640)(a)(5) of the Head Start.  Head Start promotes the school readiness of low-incomne children through th
Head Start:  Full Year Part Day Handicapped Training & Technical Assistance Supplemental Funding Request-Cost of Living Adjustment Kenosha Unified School District Head Start Program is a center-based program serving 330 eligible three, four and
Head Start:  Full Year Part Day Handicapped Training & Technical Assistance
NORTHWESTERN ILLINOIS COMMUNITY ACTION AGENCY
This award provides for ARRA Cost of Living Adjustment(COLA) and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start Program. Head Start promotes the school readiness of low-i
Head Start Comprehensive Child and Development services for low income families
Highway Infrastructure Investment - Highway reconstruction, no added capacity (no added travel lanes) - From funding for use in any Area (flexible) and from funding for use in Areas with population equal to or less than 200,000
Rehabilitate Taxiways A,B,C, and portion of D.
Rehabilitate Taxiways A,B,C, and portions of D.
The National Nanotechnology Infrastructure Network (NNIN) is a partnership of 14 institutions (Cornell University, Georgia Institute of Technology, Harvard University, Howard University, , Pennsylvania State University, Stanford University, Uni
NNIN: NATIONAL NANOTECHNOLOGY INFRASTRUCTURE NETWORK CAP EQUIP ONLY
US 395/Spokane Co Line to Loon Lake - Paving
• ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act
BOARD OF PUBLIC EDUCATION SCHOOL DISTRICT OF PITTSBURGH (INC)
Award Description: Head Start 2009 ARRA COLA Quality Improvement Funding, Allegheny County, full day (6 hour) program, purpose of Head Start is to provide early childhood education to low-income children ages 3-5.
Head Start 2009 ARRA COLA Quality Improvement Fund
TRI-COUNTY COMMUNITY ACTION AGENCY, INC.
Head Start AARA - Temporary Cost of Living and Quality Improvement Funds to provide Current Head Start Staff an increase in salaries and fringes, and funds to purchase classroom supplies.
Head Start 2009 ARRA COLA, Quality Improvement
This Migrant Head Start funding will be used for a 1.84% COLA as well as certain Quality Improvement areas, which are comprised of; seasonal medical benefits, travel to a conference designed to improve skills, language assessments, staff comple
ARRA Cost of Living Adustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640 (a)(5) of the Head Start Act
The ARRA funds grant was written to improve the Braxton County Head Start program in the following:  1. Funds were allotted to provide playground equipment thus improving opportunities for students to have physical movement during the school da
Head Start /Early Head Start  COLA/Quality Improvements - Provide 1.84% COLA increase to all HS/EHS employees, provide quality improvements in compensation & in quality of teachers, assistant teachers through increased professional development.
Program initiatives funded by this grant include $10,466 for Mental Health Services (including classroom observations by licensed professionals in order to assist teaching staff in developing individual plans that meet the specific needs of the
This award provides ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of section 640(a)(5) of the Head Start Act by providing cost of living increases and related fringe benefits,improving the
Head Start  2009 ARRA COLA Quality Imprrovement
The Head Start Quality Improvement funds were used to purchase new Head Start preschool furniture, equipment, and educational materials that will replace  materials that were worn and in disrepair.  Funds were also used to replace the roofs and
HEAD START 2009 ARRA COLA AND QUALITY IMPROVEMENT FUNDING 1.84% was inputted into 401K accounts opened by 44 staff members that had not had a retirement plan prior to this. A poured rubber playgound surface was installed providing for a safe su
WILLIAMSBURG JAMES CITY COUNTY COMMUNITY ACTION AGENCY INC
This award provided for ARRA cost of living adjustment (COLA) and quality improvement funding consistant with the provision of Section 640(a)(5) of the Head Start Act for the Head Start Program.  Expanded (2) Head Start classrooms from 160 days
Head Start 2009 COLA Quality Improvement Funding
MAZIQUE, EDWARD C PARENT CHILD CENTER, INC
ARRA cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act
Head Start 2009 ARRA COLA  and Quality Improvement
ARRA Cost of Living (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act.
This award Year One funds to expand Head Start Services to 34 additional children in Laurel and Harrington, Delaware. Service to children and families will be provided through the part-day, center based (4hours per day, 5 days per week, 160 day
The WPHA will make improvements to the lobby area in the Lakeview Senior buidling.  Improvements will include an expansion of the lobby area and the creation of supportive services space on the main level.  The removal of 5 units will allow for
New Multifamily Housing Construction (except Operative Builders)
Maunaloa Highway Resurfacing, Hoolehua to Vicinity of Keonelele Avenue
The Carrollton Area Regional Economic Development project will allow wastewater collections facility upgrades and expansion to serve existing and future commercial and industrial needs. The project will create additional jobs and boost private
Carrollton Area Regional Economic Development Project
This award provides for ARRA Cost of Living Adjustment (COLA $943,405), and Quality Improvement Funding ($2,518,785) consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start and/or Early Head Start program. H
Head Start ARRA COLA Quality Improvement Funding
WESTERN KENTUCKY UNIVERSITY RESEARCH FOUNDATION INC
Head Start 2009 ARRA COLA quality improvement funding.  These funds provide a 1.84% increase in the amount of $23,442 cost of living increase for Head Start.  This action also awards quality improvement funds of $69,161 for Head Start.
1.84% Head Start and Early Head Start ARRA COLA and ARRA Quality supplement for Teachers and Family Advocates and Fringes for $221,291.27; facility supplies and maintenance for $82,057.73; local travel for $15,372.00; legal fees for facility pu
Administration of Human Resource Programs (except Education, Public Health, and Veterans' Affairs Programs)
CLARKSVILLE-MONTGOMERY COUNTY COMMUNITY ACTION AGENCY
Head Start 2009 ARRA Cola Quality Improvement
LAKE CUMBERLAND COMMUNITY ACTION AGENCY INC
Head Start / Early Head Start COLA and Quality Improvement Lake Cumberland Community Action Agency, Head Start serves a total of 864 children pre-birth to 5 years old.  Lake Cumberland offers the Head Start and Early Head Start options.  Head S
HEAD START 2009 ARRA COLA QUALITY INPROVEMENT FUNDING
REDLANDS CHRISTIAN MIGRANT ASSOCIATION, INC.
ARRA COLA and Quality Improvement funding consistent with the provisions of Section 640(a)(5) of the Head Start Act.  RCMA's Health Insurance Benefits increased 14.6% this year. Our plan is to use ARRA funds to offset this increase rather than
ARRA Cost of Living Adjustment (COLA) and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act.ARRA Cost of Living Adjustment (COLA) and Quality Improvement Funding consistent with the provisions
Cost Of Living Adjustment and Quality Improvement Project.  The purpose of this project is to award each staff person a salary Cost of Living Adjustment and improve several centers to meet day care licensing standards.
This award provided for ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with provisions of section 640(a)(5) of the Head Start Act for the Head Start and/or Early Head Start program.  Head Start promotes school
ECONOMIC OPPORTUNITY FOR SAVANNAH-CHATHAM COUNTY AREA, INC.
This award provides funding for ARRA Cost of Living Adjustment and Quality Improvement Funding.  The award is in-line with the Head Start/Early Head Start Act(Section 640(a)(5)).  Head Start/Early Head Start serves 899 children of low-income fa
ARRA Cost of Living Adjustment COLA and Quality Improvement Funding.   Constant with the provision of section 640(a) (5) of the Head Start Act.
COMMUNITY ACTION OF SOUTHERN KENTUCKY INC
Head Start ARRA Cost of Living (COLA) and Quality Improvement (QI) funding consistent with the provisions of Section 640 (a)(5) of the Head Start Act.
KENTUCKY RIVER FOOTHILLS DEVELOPMENT COUNCIL, INCORPORATED
ARRA COLA and Quality Funds will be used to hire additional teachers, purchase 3 school buses, provide professional development to teaching staff to improve staff qualifications and to increase the compensation and benefits of staff through a c
WAYNE ACTION GROUP FOR ECONOMIC SOLVENCY, INC
This award provides for ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with provisions of Section 640(a)(5) of the Head Start Act for the Head Start and/or Early Head Start program. Head Start promotes the sch
Head Start Quality Improvement & COLA (ARRA)
MC DOWELL COUNTY BOARD OF EDUCATION (INC)
Award Title: Head Start 2009 ARRA COLA Quality Improvement Funding. This award provides for ARRA Cost of Living Adjustment (COLA), and Quality Improvement funding consistent with the provisions of Section 640(a)(5) of the Head Start Act.  Head
ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act provided to Murray Head Start and Early Head Start under the American Recovery and Reinvestment Act
SALISBURY-ROWAN COMMUNITY ACTION AGENCY INCORPORATED
ARRA Cost of Living Adjustment (COLA) and Quality Improvement Funding consistent with the provision of Section 640(a)(5) of the Head Start Act for the Head Start and/or Early Head Start program.  Head Start promotes the school readiness of low-
FRIENDS OF CHILDREN OF MISSISSIPPI, INC.
Head Start and Early  Head Start 2009 ARRA Quality Improvement; Friends Of Children Of Miss. Inc. granted all employees a 1.84% increase in salary. At least 50 % of the Quality Improvement funds were use to allocate and adjust salaries of the E
Provided for ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding. Head Start promotes the school readiness of low-income children through the provision of comprehensive health, developmental and family services.
HEAD START 2009 ARRA COLA QUALITY IMPROVEMENT FUNDING PA-22 FYPD
ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start and Early Head Start program.
Head Start 2009 ARRA/ COLA/ Quality Improvement Funding
ARRA Cost of Living Adjustment(COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start program.  Head Start promotes the school readiness fo low-income children through
This award provided for ARRA Cost of Living Adjustment (COLKA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act fotr the Head Start and/or Early Head Start program.  Head Start promotes
ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provision of Section 640 (a) (5) of the Head Start Act.
Head Start and Early Head Start 2009 ARRA COLA Quality Improvement Funding
ARRA Cost of Living and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act
ARRA cost of living adjustment (COLA), and Quality Improvement (QI)Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act. Head Start provides low-income children and their families with comprehensive health, developm
ARRA Cost of Living Adjustment(COLA), and Quality Improvement Funding
Agency provides assistance for educational personnel to complete postsecondary course work in Early Childhood Education. COLA activities Agency employes an additional classrooom staff to reduce the child/adult ratio in the classroom. Agency wil
Head Start ARRA COLA Quality Improvement funding
Head Start 2009 ARRA COLA and Quality Improovement Funds
Head Start 2009 ARRA COLA and Quality Improvement Funding
ARRA Expansion Funding was used to replenish furniture,  equipment, supplies and employ Teachers, Assistant Teachers and support staff necessary to provide comprehensive Head Start services to low-income families.
Highway Infrastructure Investment - Highway resurfacing and bridge repair - From funding for use in any Area (flexible)
HEALTH AND ENVIRONMENT, KANSAS DEPARTMENT OF
This initiative will significantly expand the awareness of proper infection control technique among ASCs and SAs, increase the extent to which infection control deficiencies are both identified and remedied, and prevent future serious infection
Ambulatory Surgical Center Healthcare Associated Infection Prevention Initiative.
The Synchrotron Radiation Center (SRC) is a national research laboratory operated by the Graduate School of the University of Wisconsin - Madison with funding from the National Science Foundation Division of Materials Research. The SRC uses an
ARRA Support of Synchrotron Radiation Center Operations
SR 27 From Intersection of 27 & 28 to 10 miles North ending at end of maintenance section
FY2009 ARRA Cost of Living Adjustment (COLA) and Quality Improvement Funding (QI) Consistent with the provisions of Section 640 (a) (5) of the Head Start Act.
This award provides for ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start and Early Head Start program. Head Start and Early Head
This award provides ARRA Cost of Living Adjustment (COLA) and Quality Improvement Funding consistent with the provisions of the Head Start Act for Head Start and Early Head Start programs.  Head Start promotes the school readiness of low-income
Fund Year 2009, ARRA, COLA and Quality Improvement project.  Funds were used to offer a permanent COLA increase for all Head Start staff and the related fringe benefits associated with the increase.  Also, funds were allocated for higher than n
ACTION FOR A BETTER COMMUNITY, INCORPORATED
This award provides for ARRA Cost of Living Adjustment (COLA) and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start and Early Head Start programs. Head Start/Early Head Star
REGIONAL ECONOMIC COMMUNITY ACTION PROGRAM, INC.
The Fiscal Year 2009 ARRA Cost of Living/Quality Improvement project to RECAP, Inc. Western Orange County Head Start program services to 196 Head Start eligible children and families who reside in the western part of Orange County including the
This award provides for ARRA Cost of Living Adjustment (COLA), and Quality Improvement funding consistent with the provision of Section 640(a)(5) of the Head Start Act for the Head Start Program.  Head Start promotes the school readiness of low
KINGSBRIDGE HEIGHTS COMMUNITY CENTER INC
The Kingsbridge Heights Community Center is located in Bronx, New York. This grant is to enhancee the services currently being delivered at its Early Head Start Program.  This is a program which provides family-centered services for low-income
ARRA Cost of Living Adjustment(COLA), and Quality Improvement Funding consistent with the provision of Section 640(a)(5) of the Head Start Act
Head Start  Program Municipality of Patillas
EPISCOPAL SOCIAL SERVICES OF NEW YORK, INC.
The action awards a cost-of-living adjustment (COLA) increase of 1.84% in the amount of $14,879 for Early Head Start.  These funds must be obligated to pay for approved costs over the 12-month period following the effective date of this grant o
FY2009 ARRA COLA / QI: To improve the physical facilities of the centers, to provide salary retention incentive and, to train and certificate direct services personnel.
ACELERO LEARNING MONMOUTH COUNTY HEAD START INC.
ARRA Cost of Living and Quality Improvement funding for the Monmouth and Middlesex counties, New Jersey Head Start program serving 1156 children.  Program funding provides payroll increases for permanent and temporary staff, improved physical s
Head Start/ Early Head Start ARRA Expansion-this award provides for ARRA Early Head Start expansion funding to provide services for 62 additional children. It also provides ARRA Head Start expansion funding to provide services for 34 additional
THIS AWARD PROVIDES FUNDS FOR ARRA HEAD START EXPANSION FUNDED TO SERVE 34 CHILDREN. THE PROGRAM PROVIDES COMPREHENSIVE SERVICES FOR LOW-INCOME FAMILIES WITH YOUNG CHILDREN (4 TO 5)TO PROMOTE THE HEALTHY DEVELOPMENT OF CHILDREN AND FAMILIES.  W
2009 Head Start Arra Expansion to expand Head Start services to additional children. Funding will support an increase in the enrollment of additional children as well as create new teaching and other positions in Head Start programs.  The Head
HEAD START EXPANSION (ARRA) Provide Fullday Education to 15 Low-Income children and families.Head Start promotes the school readiness of low-income children through the provision of comprehensive health, educational, developmental and family se
Renovate Senior Center to include a courtroom that is handicap accessible.
STIM 9.80 0300045; Campbell County; Gillette to Pinetree/WYO 59; reference markers 9.80 to 15.10; overlay.
, an acronym for Lone Star tick serpins. Sequence and expression data analyses have revealed that 10 of the 19 Lospin cDNAs encode for Lospin proteins that are potentially secreted into tick saliva during tick feeding. Our hypothesis is that, t
SERINE PROTEINASE INHIBITORS (SEPRINS) IN TICK FEEDING AND PHYSIOLOGY
This award provides for ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start and Early Head Start programs. Head Start and Early Head
EASTERN SHORE AREA AGENCY ON AGING/COMMUNITY ACTION AGENCY
ESAAA/CAA was awarded and used funds to a.) purchase a new curriculum for Head Start classrooms b.) renovate sites/classrooms to ensure health and safety for children and staff c.) partial funding for a new vehicle to transport Head Start child
Greenbrier County recently moved in the Universal Model for PK, meaning all 4 year old and 3 year old eligible students can attend one of our PK centers
Head Start Quality Improvement & COLA.  Cost of living increase applies to all federally funded positions to increase by 3.06% for salaries and fringe.  Additional ARRA COLA of 1.84% was also applied to salaries and requisite fringe (Virginia R
The awarded funds will provide an increase in salaries and benefit for teachers, social workers and family counselors.  In adition, improve the program particulary in Health and safety items.  Several pieces of kitchen equipment were repaired i
AARA Cost of Living Admustment (COLA) and quality improvement funding consistent with the provision of 640(a)(5).
ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding, consistent with the provisions of Section 640 (a)(5) of the Head Start Act
COMMUNITY ACTION OF SOUTHEASTERN WEST VIRGINIA, INC.
CASE WV Head Start cost-of-living adjustment (COLA) increase of 1.84% in the amount of 39,532 and quality improvement funds of $116,780. The program is funded to serve 309 children and families in Mercer and Summers counties.  We offer center-b
CASE WV Head Start COLA & Quality Improvement
ARRA Cost  of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act.   ARRA COLA funding is being used for the following purposes: 1. To increase wages of all Federal
Providing supplemental funding to our Head Start Program. Head Start provides services for 452 three and four year old children from low-income level families. Head Start serves in the cities of Lynchburg and Bedford and the counties of Amherst
Monticello Area Community Action Agency Head Start program provides preschool services that address all areas of child development and learning for 213 three and four year old children primarily from families whose incomes are below the federal
Head Start Quality Improvement and COLA (ARRA)These funds were used to create two temporary data entry positions, funds towards staff pay for maintenance and the Education Coordinator as well as trainings for all staff and new staff. Trainings
COMMUNITY ACTION PARTNERSHIP OF MERCER COUNTY INC
COLA - HS and HSSAP staff received the mandatory Cost of Living increase.  Hired a part-time EHS homevisitor. Increased six-hour classroom assistant to eight-hours. Quality Improvement- Restored transportation to Jamestown classroom for the res
Quality improvement funding for Head Start program within Prince George's County of Maryland. Key expected outcomes are: (1) Hire two bilingual social service workers; (2) college-level tuition to train 42 staff; (3) obesity prevention program;
Head Start 2009 ARRA COLA Quality Improvement Funding Cost of Living Allocation for all staff. At least 50% of the Quality Improvement to be used for training and technical assistance. The other half of the Quality Improvement money to be used
SOUTHWESTERN COMMUNITY ACTION COUNCIL INC
The award title is Head Start 2009 ARRA COLA Quality Improvement Funding. This is discretionary funding for our Head Start and Early Head Start programs which includes funding for employee wage supplements with the associated fringes/additives,
This COLA/ Quality Grant will assist in meeting the challenges of the rising health care and salary costs that are mandated by the school based program.   Quality funds are providing education support to employees to enhance the current Kanawha
to be used by our Home Visitor Teachers to enhance the Home Visiting program curriculum.
Early Head Start 2009 ARRA COLA Quality Improvement Funding
ARRA funds are being used for our Head Start and Early Head Start programs for increases in staff salaries and benefits and for quality improvement.  The base rate and COLA of staff in both programs have been adjusted upwards to more closely me
ARRA Cost of Living Adjustment;Quality improvment improvement funding consistent with the provisions of Section 640(a)(5) of the Head Start Act
HEAD START 2009 ARRA QUALITY IMPROVEMENT
HEAD START ARRA COLA QUALITY IMPROVEMENT FUNDING
Head Start ARRA expansion for 180 income-eligible at-risk children (90 children in each of 2 years)ages 3 and 4 in Berkeley, Jefferson, and Morgan Counties in WV.Funding  supports teachers, classroom assistants, bus drivers and family service s
.  This grant awards funds made available to the Head Start program to expand Head Start services to 17 additional children in Page County Virginia. The Head Start Program, launched in 1965, is a program of the United States Department of Healt
This grant will provide additional Head Start services to 20 children in DC's Ward 8 community.
This project continues Scripps Institution of Oceanography's role as the Pacific Facility of the Ocean-Bottom Seismic Instrument Pool. Scripps maintains a fleet of 75 OBS/H of which 25 can be used in a long-deployment, broadband configuration f
Grant funding for construction of Phase I NW 44th Avenue, a new road
Phase I NW 44th Avenue Road Construction Project
Replacement of the steel bulkhead at Berth 230 which supports the REK Pier Berths 226 and 227.
Dillons Corner Br. No. 481, Pt. Judith  Br. No. 482
Head Start 2009 ARRA COLA Quality Improvement Funding was used to help provide quaility service to 459 children in Durham, NC area. The funding helped to improve the safety and quailty of playgrounds, provide better bus transportation, improve
JEFFERSON COUNTY CHILD DEVELOPMENT COUNCIL
Head Sart ARRA COLA & Quality Improvement
Head Sart ARRA COLA and Quality Imrprovment
This award provides for ARRA Cost of Living Adjustment (COLA) and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start and Early Head Start program.  Head Start promotes the sc
RANDOLPH CO BOARD OF EDUCATION HEAD START
Randolph County Board of Education Head Start Program, serving 125 children in Randolph County, GA, center based enrollment with full day classes for 3 and 4 year olds.  Our purpose is to promote school readiness for primarily low income childr
Randolph County Board of Educaiton Head Start
This award provides for ARRA Cost of Living Adjustment (COLA) and Quality Improvement Funding consistent with the provisions of Section 640(a)(5)of the Head Start Act for the Head Start Or Early Head Start program.  Head Start promotes the scho
ARRA funding for a Cost of Living Award in the amount of 1.84% for the fiscal year ending September 1, 2009.  The ARRA funding will, in addition to COLA, provide funding that will offset the rising cost of fuel for 15 buses that provide transpo
COUNTY OF SANTA ROSA BOARD OF PUBLIC INSTRUCTION
Award Description  The following information is the Award Description for 04SE0384.  The award title is Head Start 2009 ARRA Cost of Living Adjustments (COLA) Quality Improvement Funding.  A description of the award title is as follows: The ove
Head Start 2009 ARRA COLA Quality Improvement Funding, The Martin County School District Head Start program serves 262 low income children and families in the Indiantown, Port Salerno, and Stuart areas of Martin County.  Head Start is a compreh
This award provides for ARRA COLA and Quality Improvement funding consistent with the provisions of Sec. 640(a)(5) of the Head Start program.   Head Start promotes the School Readiness of low income children through comprehensive health develop
CHOANOKE AREA DEVELOPMENT ASSOCIATION OF NORTH CAROLINA, INCORPORATED
Head Start 2009 ARRA COLA Quality Improvement Funding.  funds awared to implement the Head Start mandated COLA, purchase os buses, and for staff development.  T & TA funds used for staff development.  Funds also used to improve playgrounds and
Headstart ARRA Cost of Living Adjustment (Cola), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act.  There are 373 children enrolled and our program is center based.  We serve Camden, Chow
COMM ACTN AGCY HUNTSVILLE-MDSN & LMST COUNS INC
Head Start 2009 ARRA COLA Quality Improvement Funding  Cost-of-Living Adjustment of 1.84% to improve Head Start employees' salaries and pay for increased cost of fringe benefits. Quality Improvement funds are for repairs and maintenance to Head
HEAD START QUALITY IMPROVEMENT AND COLA.   OVER 51% OF THE QI MONIES ARE TO BE USED FOR BRINGING THE EDUCATION STAFF BACK A WEEK AND TWO DAYS EARLY AND THE FAMILY SERVICE WORKERS A WEEK EARLIER FOR PROFESSIONAL DEVELOPMENT TRAINING.  THERE ARE
Head Start 2009 ARRA COLA QUALITY IMPROVEMENT FUNDING
BURLINGTON COUNTY COMMUNITY ACTION PROGRAM
Burlington County (NJ) Community Action Program (BCCAP) has provided high-quality Head Start services in Burlington County for more than forty years.  BCCAP enrolls and provides services for 431 income and age eligibility children and their fam
Burlington County Community Action Program
To support an existing Head Start Program providing a cost of live of 1.84% for all Head Start Staff and an additional 5.083% cost of living increase for teaching staff (both plus fringe benefits); to provide funds for the purchase of a bus to
Head Start, Early Head start is a federally fudned program which provides comprehensive services to pregnanct women, infants, toddlers and preschool children and their families.  Services are provided in the area of education, health, nutrition
EARLY CHILDHOOD LEARNING CENTER OF GREENE COUNTY
FY2009 ARRA COLA / QI -  Cost-of living adjustment (COLA) increase of 1.84% in the amount of $28,244 for Head Start and quality improvement funds of $ 74,452 for Head Start.
Early Head Start Quality Improvements and COLA (ARRA).  The award provides for cost of living adjustment and quality improvement funding consistent with the provision of Section 640(a)(5) of the Head Start Act for the Head Start and/or Early He
SARATOGA COUNTY ECONOMIC OPPORTUNITY COUNCIL
ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act. SCEOC serves 310 Head Start and 124 EHS children throughout Saratoga County in various locations.
The Children's Community Head Start served an additional 16 children/families in a full day, extended option, providing early morning/late afternoon care to enable parents to work/go to school.  A new Early Head Start component served 32 center
The Head Start expansion award (02SH0297), an expansion grant for $136,736, (and $160,140 continuation award) enabled our Head Start program to increase the enrollment by eighteen slots, thus addressing the need for increased Head Start slots i
Head Start ARRA Expansion of Head Start in Ilion, Herkimer County, NY.  Will provide 18 low-income children and their families with Head Start services.  Head Start promotes the school readiness of low-income children through the provision of c
The award Provides for ARRA Head Start Expansion funded to serve 54 children coming from low-income families and residing in Sunset Park, Brooklyn. The Head Start program provides family-centered services for low-income families with preschoole
STIM 2.93 0300044; Campbell County; Gillette to Pinetree/WYO 59; reference markers 2.93 to 9.72; overlay.
Mount Pleasant Community Facilities Grant
Piilani Highway Pavement Preventive Maintenance, Lipoa Street to Kilohana Drive
SR 318, Sunnyside Cutoff, from 18.5 MS of the LN/NY County Line to 10 MN of the LN/NY County Line
Highway Infrastructure Investment - Bridge replacement, no added capacity (no added travel lanes) - From funds for use in any Area (flexible)
The FWS Program provides funds that are earned through part-time employment to assist students in financing the costs of postsecondary education.
Federal Work Study Program/America Reads/Job Location
Hana Highway Pavement Preventive Maintenance, Kaupakalua Road to Huelo
ALLEGHENY LUTHERAN SOCIAL MINISTRIES, INC.
Award description: Head Start 2009 ARRA Cost of Living Allowance (COLA) and Quality Improvement funding was awarded to Bedford/Fulton County Head Start which serves 202 eligible children in center based, combination and home-based options, depe
Head Start 2009 ARRA COLA/Quality Improvement This award provides for ARRA Cost of Living Adjustment and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start Program. Head Star
ARRA funds will be  used to  supplement employee wages through the required  1.84% COLA to all staff, as well as to supplement the wages of  designated job classes that have been determined to be below  market level, based on our most recent sa
Head Start 2009 ARRA COLA & Quality Improvement Funding
ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act This award provides for ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding cons
Head Start promotes the school readiness of low-income children through the provision of comprehensive health, developmental and family services.Funding was appropriated for equipment/supplies during the funding period and it was paid out durin
Head Start 2009 ARRA COLA/quality improvement Funding
Award number 03SE0231 Head Start Quality Improvement and COLA Funding consistent with the porvisions of Section 640(a)(5)of the Head Start Act This grant was used to provide cost of living increases in salary for Head Start employees, and provi
ARRA Cost of Living Adjustment (COLA) and Quality Improvement Funding Consistent with the provisions of Section 640(a)(5) of the Head Start Act.  This funding will enhance the Head Start Program that is currently serving 138 children in Frankli
With the temporary 1.84% ARRA COLA award, our 40 employees received a pay raise as well as assistance with their share of health and dental insurance premiums.  The Quality Improvement funds were used to provide monies for education personnel a
ARRA Cost of Living Adjustment (COLA),and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start program.  Head Start promotes the school readiness of low income children through
COMMUNITY ACTION PROGRAM OF LANCASTER COUNTY
This award provides for ARRA Cost of Living Adjustment (COLA)and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start and/or Early Head Start program. Head Start promotes the s
This award provide for ARRA Cost of Living Adjustment (COLA)and Quality Improvement Funding consistant with the provisions of Section 640(a)(5)of the Head Start Act for the Head Start program. Head Start school readiness of low-income children
YOUNG WOMENS CHRISTIAN ASSOCIATION OF MEADVILLE
This award provides for ARRA, Cost of Living Adjustment (COLA) and Quality Improvement Funding consistent with the provisions of Section 640 (a)(5) of the Head Start Act for the Head Start and/or Early Head Start program.  Head Start promotes t
ARRA Cost of Living (COLA) and Quality Improvement Funding consistent with the provisions of Section (a)(5) of the Head Start Act.
NORTH-CENTRAL WEST VIRGINIA COMMUNITY ACTION ASSOCIATION, INC
This award provides the Grantee ARRA Cost of Living (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the NCWVCAA Head Start Act for the Head Start and Early Head Start program as follows: Grantee Ac
The use of the Head Start Quality Improvement and COLA (ARRA) funding is consistent with the provisions of Section 640 (a)(5) of the Head Start Act.  The overall purpose of the action funded by the Recovery Act is to provide an environment for
This award provides for ARRA Cost of Living Adjustment (COLA), and Quality Improvement funding consistent with the provisions of Section 640(1)(5)of the Head StartAct for the Heard Strt and/or Early Headt Start programs.  Head Start promotes th
ARRA COLA Improvement is being used for a temporary .55% increase to staff's wages for one year unless further funding becomes available.  Head Start employees have not received a raise in several years so this decision was based on an effort t
NICHOLAS COMMUNITY ACTION PARTNERSHIP INC
Head Start 2009 ARRA COLA & Quality Improvement Funding The COLA was used to retain current employees and increase one employee to twelve months. The ARRA QI was used to repair and maintain the Stand alone facilities to meet the Child Care Lice
HEAD START 2009 ARRA COLA AND QUALITY IMPROVEMENT FUNDING
Grant funds made available to expand Head Start services to (34)additional children in Lackawanna,Susquehanna,Wayne and Pike Counties.Services to children and families are provided through the center based option.
New River Community Action Head Start Expansion is used to serve 17 additional children & their families using the scientifically based High Scope Curriculum.  The desired outcomes are (1)that every child is socially, emotionally, physically &
SISKIYOU TRAINING & EMPLOYMENT PROGRAM, INC
related materials - but at a more advanced level.  The training products will be used by STEP clients and as a supplement for College of the Siskiyous CalWORKS - keeping them engaged in required Welfare-to-Work activities.  It is STEP's intent
Workplace Readiness and Retention Series
conduit all with related structures and appurtenances. The total project cost is estimated to be $600,000 with the Rockcastle County Fiscal Court providing 30% match.  The utility improvements will serve the new 25,000 sq. ft.  SOURCECORP faci
Rockcastle County Industrial Park South Infrastructure Project
The Center for IDEAs (Phase II) project involves the construction of a new three-story facility that will include business incubator, office, and meeting space.  The facility will be located adjacent to the existing Renasant Center for IDEAs fa
Lee County/Community Development Foundation: Center for IDEAs (Phase II)
American Recovery and Reimbursement Award.This award provides for ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Seciton 640(a)(5) of the Head Start Act for the Head Start and/or Early H
Head Start 2009 ARRA COLA/Quality Improvement award 717 families served Program option: Full-day, single session Jackson County, Mississippi Purpose:  To improve facilities in order to continue providing services in a safe, healthy, and invitin
Head Start 2009 ARRA COLA/Quality Improvement
The Baldwin County Early Learning Center applied for ARRA funds to serve 210 low-income Head Start children in Baldwin County, Georgia through a center-based, full day early childhood education setting aligned with the local school district sch
NASHVILLE & DAVIDSON COUNTY, METROPOLITAN GOVERNMENT OF
ARRA Cost of Living Adjustment (COLA) and Quality Improvement funding consistent with the provisions of Section 640(a)(5) of the Head Start Act.  The purpose and outcome for the ARRA Cost of Living Adjustment (COLA) and Quality Improvement fund
ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5)of the Head Start Act
CENTRAL KENTUCKY COMMUNITY ACTION COUNCIL, INCORPORATED
ARRA Cost of Living Adjustment and Quality Improvement funding consistent with the provisions of Section 640 (a)(5) of the Head Start Act. Funding used to provide 120 Head Start Staff with salary and fringe benefit increases.
First Quarter: Head Start 2009 ARRA COLA Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act ($1,269.00 distributed to offset increased retirement costs.)    Second Quarter: Three Payments made
BLUE RIDGE OPPORTUNITY COMMISSION, INCORPORATED
This award provides for ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Blue Ridge Opportunity Commission Head Start Program. Head Start pr
ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding Consistent with the provisions of Section 640(a)(5) of the Head Start Act
Head Start 2009 ARRA COLA, Quality Improvement Funding
GULF COAST COMMUNITY ACTION AGENCY, INC.
Head Start 2009 ARRA/COLA/Quality Improvement Funding granted to Gulf Coast Community Action Agency for use in our Head Start program.  We have seven (7) Head Start centers located in Harrison County, Mississippi serving 1,368 children. The ARR
Gulf Coast Community Action Agency Head Start Program
This award provides for ARRA Cost of Living Adjustment (COLA),and Quality Improvement Funding consistent with the provisions of Section 640(a)(5)of the Head Start Act.  Head Start promotes the school readiness of low-income children through the
Head Start 2009 ARRA/COLA Quality Improvement
HEAD START ARRA COLA & Quality Improvement Funding to be utilized for salary increases, increased costs of benefits, coursework and training for staff to meet the 2013 staff qualification guidelines set forth in the Head Start Act 2007, and pla
MACON-BIBB COUNTY ECONOMIC OPPORTUNITY COUNCIL, INC.
Head Start 2009 ARRA COLA used to provide salary and fringe increases to eligible staff.  Also Quality Improvement Funding used to bring staff up to the required minimum wage as well as provide for the purchase supplies and a vehicle.
The award is from the American Recovery and Reinvestment Act(ARRA)which, include Cost of Living  Adjustment (COLA), and Quality Improvement Funding. The award was used for the Pine Hills project the replacement of 3 modules at the Pine Hills He
ALLEGANY COUNTY COMMUNITY OPPORTUNITIES AND RURAL DEVELOPMEN
Financial Assistance Award; ARRA Cost of Living Adjustment and Quality Improvement Funding consistent with the provision of Section 640a(5) of the Head Start Act. Provide 1.84% COLA for HS and EHS employees and construction of shade shelters. A
LA PENINSULA COMMUNITY ORGANIZATION OF HEAD START
ARRA COLA AND QUALITY IMPROVEMENT FUNDING CONSISTENT WITH THE PROVISION OF SECTION 640 (a)(5) OF THE HEAD START ACT
TRENTON HEAD START CHILD DEVELOPMENT & FAMILY RESOURCE CTR
FY 2009 ARRA COLA & Quality Improvement.  Funds from this grant were used to give Head Start staff not covered by the Abbott contract a temporary cost of living adjustment and to supplement the purchase of a new bus that replaced an existing bu
Head Start ARRA COLA and Quality Improvement funds will be used to pay for increasing cost of fringe benefits for over 3,000 Head Start staff in 74 Delegate Agencies.  ARRA Quality Improvement funds will also be used for improvements in the phy
WASHINGTON COUNTY ECONOMIC OPPORTUNITY COUNCIL, INC.
This award provided ARRA Cost of Living and Quality Improvement Funds for Head Start and Early Head Start   programs. Head Start promotes the school readiness of low-income children through the provision of comprehensive health, developmental,
for classroom teams,  and program observation tools to reinforce the ongoing utilization of strategies identified and taught. In addition, staff training regarding social emotional strategies was increased and materials to support implementati
PEOPLES EQUAL ACTION AND COMMUNITY EFFORT INC
This award provides for ARRA Cost of Living Adjustment (COLA), and Quality Improvement funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start and Early Head Start program.  Head Start promotes the s
Head Start quality Improvement and COLA (ARRA)
ARRA COLA and Quality Improvement funding consistent with the provisions of Section 640(a)(5) of the Head Start Act to support cost of living increases, substitute teachers to cover classes when teachers are engaged in professional development,
This action awards a cost-of-living adjustment (COLA) increase of 1.84% in the amount of $17,564 for Early Head Start.  These funds must be obligated to pay for approved costs over the 12-month period following the effective date of this grant
NEW SQUARE COMMUNITY IMPROVEMENT COUNCIL INC
This action awards a cost of living adjustment increase of 1.84% in the amount of $17,679. and quality improvement funds of $40,531. for Early Head Start.
ARRA Cost of Living Adjustment (COL,A), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act.
ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section (640)(a)(5) of the Head Start Act
This grant funds an additional classroom at the Sacred Heart Head Start Center.  It is an inclusion classroom which serves special needs children in a mainstream setting. The classroom serves 20 children of which 10 children have special needs.
FAMILY HEALTH CENTER OF A MARSHFIELD INC
LOAN FOR CONSTRUCTION OF A DENTAL CENTER IN MEDFORD WISCONSIN.  WILL PROVIDE EMPLOYMENT FOR 5 FTES DENTISTS, 5 FTES HYGIENST, AND 20+ FTE SUPPORT POSITIONS.  APPROXIMATELY 90% OF PATIENTS WILL BE AT 200% AND BELOW FEDERAL POVERTY LEVEL.DENTAL C
FAMILY HEALTH CENTER OF MARSHFIELD, INC. MEDFORD, WI PROJECT
FAA Airport Improvement Program Grant for Non-primary development projects in the State Block Grant Program.  This grant provides 100% federal funding for five general aviation airport construction projects in Georgia.
Federal Aviation Administration-Grants-in-aid for Airports, Recovery Act
Highway US-34, Air Park to I-180, Lincoln
USDA, Office of Small and Disadvantaged Business
This Project will enable expansion of the City of Ladysmith, Wisconsin's Fritz Avenue manufacturing facilities by providing for addition of leaseable manufacturing space, which is expected to save 5 jobs.
Lessors of Nonresidential Buildings (except Miniwarehouses)
FCC DTV Conversion Help Centers performed hands-on demonstrations of how to install a digital-to-analog converter box and a broadcast antenna to an analog TV, demonstrations of how to properly position the antenna for the best reception of loca
Services for the Elderly and Persons with Disabilities
WARREN FOREST COUNTIES ECONOMIC OPPORTUNITY COUNCIL INC
This award provides for ARRA Cost of Living Adjustment (COLA) and Quality Improvement Funding consistent with the provisions of Section 640(a)(5)of the Head Start Act for the Head Start program.  Head Start promotes the school readiness of low-
The Head Start 2009 ARRA COLA Quality Improvement Funding awarded a cost-of-living adjustment increase of 1.84% to Head Start employees that amounted to $42,894.75 over the 12-month period following the effective date of the grant, or within th
Head Start 2009 ARRA COLA Quality Improvement funding will provide financial support adding instructional personnel, professional growth and development training for staff and educational materials and supplies to set up four additional classro
This Award provides for ARRA COLA and Quality Improvement funding consistent with the provisions of Section 640 ( a )(5) of the Head Start Act for the Loudoun County Public Schools Head Start Program. The LCPS Head Start program serves 100 chil
Head Start 2009 Cola improvement funding
PRIVATE INDUSTRY COUNCIL OF WESTMORELAND/FAYETTE, INC.
Use of ARRA COLA and Quality Improvement funds for the Head Start/Early Head Start program in Fayette County, PA which serves 534 federally funded Head Start children and 192 federally funded Early Head Start children throughout the County.  A
RALEIGH COUNTY COMMUNITY ACTION ASSOCIATION
ARRA COLA and QI. Raleigh County Community Action Head Start serves 381 children in the four days a week program option throughout Raleigh County WV. RCCAA is committed to improving lives of children and families of those we serve.
Head Start 2009 COLA Quality Improvemnet Funding
SOUTHERN MARYLAND TRI-COUNTY COMMUNITY ACTION COMMITTEE, INC
Head Start 2009 ARRA COLA Quality Improvement Funding - Extend work year for 20 staff, training, purchase bus restraints for children, classroom supplies and recognition of staff credential acheivements.
Head Start 2009 ARRA COLA Quality Improvement Funding;  COLA - 1.84% AARA funding for 31 employees  Quality Improvement - To improve the compensation package for the following personnel: Curriculum Specialist, Child Development Specialist, Heal
ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act.  Head Start provides low-income children comprehensive health, developmental and family services i
Alexandria Head Start (AHS) was awarded ARRA funds to expand HS services to 57 additional children in the City of Alexandria, Virginia. Services to children and families will be provided through the center-based option. Head Start promotes scho
The overall purpose of the Head Start Expansion project is to provide Head Start services to more children in the Crisfield, MD area (Somerset County). The project will do this by adding another 17 children to the total enrollment of the Head S
MCINTOSH TRAIL EARLY CHILDHOOD DEVELOPMENT COUNCIL INC, THE
ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640 (a)(5) of the Head Start Act.  Head Start promotes the school readiness of low-income children through the provision of compreh
LUMBEE REGIONAL DEVELOPMENT ASSOCIATES INC
1. (COLA) Cost of Living Allowance; (ARRA) American Recovery & Reinvestment Act, Quality Imporovement. Their will be 155 Head Start Children and 32 + 8 pregnant mom will be served in Robeson County. COLA/Quality Improvement: An effort to curb t
This award provided for ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start and/or Early Head Start program.  Head Start promotes th
PA22 ARRA HEAD START COLA AND PA22 ARRA HEAD START QUALITY IMPROVEMENT FUNDS.  THIS AWARD PROVIDES FOR ARRA COST OF LIVING ADJUSTMENT (COLA)AND QUALITY IMPROVEMENT FUNDING CONSISTENT WITH THE PROVISIONS OF SECTION 640(a)(5) OF THE HEAD STAR ACT
LOW COUNTRY COMMUNITY ACTION & HEAD START AGENCY INC
ARRA Cost of Living Adjustment(COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act.
Head Start/Early Head Start 2009 ARRA COLA Quality Improvement Funding.
Head Start promotes the school readiness of low-income children through the provision of comprehensive health, developmental and family services, primarily for low-income families with very young children. This ARRA funding was used in two prin
ARRA Cost of Living Adjustment (COLA), and Quality Impovemnet Funding consistent with the provision of Section 640 (a)(5) of the Head Start Act.
KCEOC COMMUNITY ACTION PARTNERSHIP, INC.
Head Start/Early Head Start 2009 ARRA Cola Quality Improvement Funding
COMMUNITY ACTION COUNCIL FOR LEXINGTON-FAYETTE, BOURBON, HARRISON & NICHOLAS COUNTIES INC
As staff attains higher degrees the Council's compensation structure provides that the individual's hourly rate of compensation increase accordingly.  These increased wages will be absorbed by base funding.  Quality funds allow an equivalent
LICKING VALLEY COMMUNITY ACTION PROGRAM INCORPORATED
~ The ARRA cost of living of 1.84% also will be used to increase the Head Start Staff hourly per rate.
ARRA COLA/Quality Improvement   This award provides for ARRA Cost of Living Adjustment and Quality Improvement Funding consistent with the Head Start Act.  Head Start promotes the school readiness of low-income children and provide quality serv
ARRA Cost Of Living Adjustment( COLA)and Quality Improvement funding consistent with the provisions of Section 640(a)(5)of the Head Start Act. Specifically, this grant will be used to underwrite our attempt to raise salaries for our classroom
Head Start 2010 ARRA COLA Quality Funding
Head Start 2009 ARRA COLA Quality Improvement Funding. Head Start Cola Activities: The agency shall provide a minimum of 1.84% COLA in salaries and fringe benefites to 101 employees over a 12 month period. Realignment for head start employees t
The overall purpose of the award is to enhance the current salaries of the agency to allow the agency to be competitive in the job market and attract and retain qualified and skilled individuals to provide qualityservices to our clients, create
JEFFERSON COUNTY COMMITTEE FOR ECONOMIC OPPORTUNITY
The Head Start Quality Improvement and COLA ARRA funds will provide a 1.84% COLA to staff, improve lighting in some classrooms and pave parking lot at our Fairmont center.  Tuition for students taking college courses to obtain their degree will
MONTGOMERY COMMUNITY ACTION COMMITTEE & CDC, INC
Head Start/Early Head Start COLA, Quality Improvement - ARRA Cost of Living Adjustment (COLA) and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act.  ARRA COLA Activities:  MCAC proposed to ut
GADSDEN HEADSTART CHILD DEVELOPMENT PROGRAM
Project Title: Head Start Stimulus 2009-ARRA/Quality Improvement Funds Three hundred and thirty-six children are served in Etowah County of Alabama.  Head Start promotes the school readiness of low-income children through the provision of compr
ARRA Cost of Living Adjustment(COLA) and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start and/or Early Head Start program.  Head Start promotes the school readiness of low-
DALLAS SELMA COMMUNITY ACTION AND COMMUNITY DEVELOPMENT
The Dallas Selma Head Start program is located in the Black Belt of Alabama. It is in one of the most economically depressed areas in the State. The Head Start 2009 ARRA COLA and Quality Improvement Funds were used for staff raises, repair and
ARRA Cost of Living Adjustment (COLA) and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act.  Award served 1,076 children in Fulton, Barrow, Madison, Jackson, Oconee and Walton counties, Georg
Head Start 2009 ARRA COLA/Quality Improvement Funding  ARRA  grant award number 04SE4580 in the amount of $117,756  enabled the Onslow County Schools Head Start (Jacksonville, NC  - Onslow County) program to enhance services to the 230  standar
The appearance and sanitation of two Early Head Start classroom environments will be improved with the purchase of new cabinets and sinks in two classrooms at a cost of $34,565.  Materials and supplies for the Early Head Start classrooms and pr
Florida State University Early Head Start Program  Created by the 1994 U.S. Congress, Early Head Start incorporates current research and best practice in providing services to low-income young children and their families. The program is designe
FSU Early Head Start - Gadsden ARRA Qi and Cola
The Head Start 2009 ARRA COLA and Quality Improvement Funding Award is consistent with the provisions of the Early Head Start Program.  Early Head Start provides comprehensive services to low income children through the provision of comprehensi
This award (ARRA Head Start Expansion) was funded to serve 100 children which were from the local community according to the Community Needs Assessment. The Head Start program provides family-centered services for low- income families to promot
Head Start promotes the school readiness of income eligible children through the provision of comprehensive health, education and family services.   This award enables 60 children and their families to participate in a center based program 5 da
ARRA Head Start Expansion thru 9/29/10 & ARRA Head Start Expansion 9/30/10 - 9/29/11 continuation for 40 children.  Head Start promotes school readiness of low-income children.  Services in Henderson and Transylvania County.
Head Start Expansion for services for 18 additional children in Powell County, KY.  There is a critical need for early education services in this geographical area as determined by the Community Needs Assessment.  Foothills will use these funds
ARRA HEAD START EXPANSION: The Clarke County School District ARRA Head Start (HS) expansion in Athens, GA increased enrollment of three year old children who are underserved by adding 68 additional center based slots. The HS expansion includes
HEALTH CARE ADMINISTRATION, FLORIDA AGENCY FOR
This initiative will significantly expand the awareness of proper infection control technique among ASCs and Sas, increase the extent to which infection control deficiencies are both identified and remedied, and prevent future serious infection
Ambulatory Surgical Center Healthcare Associated Infection Prevention Initiative
Indiana State Department of Health 2 North Meridian
FALL LINE FWY/NORTH GORDON BYPASS FROM SR 57 TO SR 243 AT LAKE
Construction of a rail spur.  Spur will provide rail service to new industrial development occurring within the business park.
All Other Professional, Scientific, and Technical Services
Head Start Full Year Handicapped Training and Technical Assistance.  This award provides for ARRA Cost of Living (COLA) and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Readiness Act for Head
MAHONING YOUNGSTOWN COMMUNITY ACTION PARTNERSHIP
ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act.The Mahoning Youngstown Community Action Partnership Head Start program serves 963 children under t
ADAMS - BROWN COUNTIES ECONOMIC OPPORTUNITIES, INC
This award provided for ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start and/or Early Head Start program. It also provided fundin
DHHS award for Head Start COLA (Cost of Living) increase of 1.84% to pay for Head Start salaries and benefits and award of quality improvement funds to be used across the program (also used for salary and benefits) to be expended prior to Septe
Head Start:  Full Year, Part Day Handicapped Training and Technical Assistance
This award provides for ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start and Early Head Start Program.  Head Start promotes the s
Head Start-Full Year Part Day Handicapped Training and Technical Assistance
This award provides for COLA and Quality Improvement Funding for Head Start.  Head Start promotes the school readiness of low-imcome children through the provision of comprehensive health, developmental and family services. The Quality Improvem
Head Start:  Full Year Part Day Handicapped Training and Technical Assistance
Head Start COLA and Quality Improvement - COLA Activities: This action awards a cost of living adjustment increase of 1.84% in the amount of $36,806 for Head Start staff salaries and fringe benefits over a 12 month period for 42 employees. Qual
Office of Intergovernmental Affairs and Regional Directors
AREA IV AGENCY ON AGING AND COMMUNITY ACTION PROGRAMS, INC.
ARRA Cost of Living Adjustment(COLA), and Quality Improvement Funding consistant with the provisions of Section 640(a)(5)of the Head Start Act
?	Head Start ARRA COLA & Quality Improvement.  Head Start serves low-income preschool children and their families. ?	591 Children 3-5 years of age. ?	567 children and families are in a Center-based classroom setting promoting school readiness b
Head Start Full Year Part Day Training & Technical Assistance
IRONTON AND LAWRENCE COUNTY AREA COMMUNITY ACTION ORGANIZATION
HEAD START: FULL YEAR PART DAY HANDICAPPED TRAINING AND TECHNICAL ASSISTANCE- COST OF LIVING ADJUSTMENT FOR NEGOTIATED STAFF AND QUALITY IMPROVEMENT FUNDING FOR THE HEAD START PROGRAM IN LAWRENCE COUNTY, OHIO
Head Start: full Year Part Day Handicapped Training and Technical Assistance
ARRA Cost of Living (COLA), and Quality Improvement Funding consisent with the provision of Section 640(a)(5) of the Head Start Act
HOOSIER UPLANDS ECONOMIC DEVELOPMENT CORPORATION
Head Start: Full Year Part Day Training & Technical Assistance  COLA and quality improvement funding.  This project award enabled Hoosier UPlands Head Start and Early Head Start the opportunity to provide a 1.84% COLA for all staff in the Head
KOOTASCA Community Action, Inc. provides center based early childhood education through Head Start to 217 children ages 3 to 5 years in the counties of Itasca and Koochiching within the State of Minnesota. This funding is for the ARRA Cost of L
Award Description: ARRA Cost of Living (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act.  Community Action Wayne/Medina operates a Pre-school and Early Head Start program serving
WESTERN EGYPTIAN ECONOMIC OPPORTUNITY COUNCIL
ARRA Cost of Living Adjustment (COLA, and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act
SOUTHWESTERN WISCONSIN COMMUNITY ACTION PROGRAM INC
ARRA Cost Of Living(COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a) (5) of the Head Start Act.  Increases the compensation and benefits of Head Start and Early Head Start staff.  Provides for professional
COMMUNITY ACTION PARTNERSHIP OF CENTRAL ILLINOIS, INC
DUBOIS-PIKE-WARRICK ECONOMIC OPPORTUNITY COMMITTEE INC
This award provides for ARRA Cost of Living Adjustment and Quality Improvement Funding consistent with the provisions of Secion 640(a)(5) fo the Head Start Act for the Head Start program.  Head Start promotes the school readiness of low-income
ERIE HURON COUNTIES COMMUNITY ACTION COMMISSION
ARRA Cost of Living Adjustment(COLA), and Quality Improvement funding consistent with provisions of Section 640 (a)(5) of the Head Start Act.  Also, funding for staff development, building repairs, utilities and vehicle operating expenses.
INDIANHEAD COMMUNITY ACTION AGENCY, INCORPORATED.
ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Secion 640(a)(5) of the Head Start Act. The overall purpose of the award was to improve the quality of the program through the use of impro
COMMUNITY AND FAMILY RESOURCE CENTER INC
This award provides for ARRA Cost of Living Adjustment (COLA) for some operating expenses such as food and utilities, and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start a
Head Start: Full year full day Hanndicapped; Training & Technical Assistance
ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act.  Council on Rural Service Programs, Inc. provides services to 1105 Head Start children and 132 Ear
ARRA COST OF LIVING (COLA), AND QUALITY IMPROVEMENT FUNDING CONSISTENT WITH THE PROVISIONS OF SECTION 640(a)(5) OF THE HEAD START ACT.
PARENT & CHILD TOGETHER FOR WEST CENTRAL ILLINOIS
This award provides for ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start and Early head Start programs. Head Start promotes the s
Head Start: Full Year/Part Day Handicapped/Training & Technical Assistance
ARRA 05SE5144 Head Start Grant - This award provides for ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act.  Head Start promotes the school readiness
This award provides ARRA COLA and Quality Improvement funding to 1) implement an across-the-board COLA increase of 1.84% for all staff, including the hourly rate of pay and fringe benefits; 2) improve the qualifications of Education and Family
Head Start  Full Year Part Day Handicapped Trainning and Technical Assistance
ARRA Cost of Living Adjustment (COLA) for all staff, and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act
The overall purposes of this award are to retain qualified staff by providing a one-time 1.84% increase in salary and fringe benefits, purchase janitorial and health/nutrition supplies, office supplies and conduct a comprehensive Community Need
Head Start ARRA COLA/ Early Head Start COLA/Head Start Quality Improvement ARRA/Early Head Start Quality Improvement ARRA
Please note we were awarded  an extension from 10/1/10 through 12/21/10.  This award provides for ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act f
This awards provides for COLA adjust and Quality Improvement funding consistent with provisions of section 640 A5 of HS Act for the HS and EHS Program. HS provides school readiness for low income children through comprehensive health and Family
ARRA Cost of Living & Quality Improvement
This award provides for ARRA Cost of Living Adjustment(COLA) increase of 1.84% in the amount of $19,433.  This award also provides Quality Improvement funds consistent with the provisions of Section 640(a)(5) of the Head Start Act of $55,933. T
HEAD START ARRA COST OF LIVING ADJUSTMENT (COLA), AND QUALITY IMPROVEMENT FUNDING CONSISTENT WITH THE PROVISIONS OF SECTION 640 (A).  GEMINUS HEAD START SERVES 1,319 CHILDREN IN LAKE AND PORTER COUNTIES OF INDIANA, WITH TWO DELEGATE AGENCIES SE
Wayne County Head Start (WCHS)Pogram ARRA Cost of Living Adjustment(COLA) and Quality Improvement Funding consistent with the provision of Section 640 (a). WCHS provides Head Start services (educational, health, nutrition, social and other serv
The COLA, ARRA, and Quality improvement funds have assisted in ensuring that compensation is adequate to retain qualified staff for the Early Head Start Program.
Head Start ARRA Expansion-Expansion of Head Start services to 32 children with disabilities.  The Head Start program provides family-centered services for low-income families with young children (3-5) to promote the healthy development of the c
NORTHWESTERN OHIO COMMUNITY ACTION COMMISSION
This award provides for ARRA Head Start Expansion funded to serve 34 children.  The Head Start program provides center based services for low-income families with children ages 3 - 5 years to promote the school readiness through the provision o
Heartland Head Start promotes the school readiness of low-income children through the provision of comprehensive health, developmental and family services.  ARRA funding provided 60 additional enrollment opportunities for eligible children and
This award provides for ARRA Head Start Expansion funding to serve an additional 40 children and their families.  The program provides comprehensive health, developmental and family-centered services for low-income families to promote the schoo
This award provides for Head Start Expansion to serve 66 children.  54 children are served in a center-based program and 12 are served in a home-based setting.  This program promotes healthy development and school readiness for children ages 3
HEAD START EXPANSION GRANT ALLOWS THE COLUMBUS URBAN LEAGUE HEAD START PROGRAM TO SERVE 100 ADDITONAL CHILDREN THROUGHOUT OUR SERVICE AREA. CUL HEAD START SERVICE AREA IS DIFINED AS FRANKIN COUNTY, OHIO SOUTH OF INTERSTATE 70.  CUL HEAD START P
US-60 (Grand Av); 99th Av to 83rd Av in PEORIA
This project will enable expansions of the City of Ladysmith, Wisconsin's Meadowbrook Center and Fritz Avenue manufacturing facilities by providing for addition of 34,500 sq. ft. of leaseable manufacturing space, which is expected to result in
The proposed investment consists of an existing 50,000 sq. ft. school building, located on a 11.3 acre site, conversion to a green energy incubator building for businesses. The conversion includes installation of geothermal heat pumps(GHPs), co
The installation of infrastructure to improve a 20+ acre brownfield industrial site.
Interior and exterior build-out and renovation of an existing building for use as a business incubator facility on he campus of the Illinois Institute of Technology. The completed Incubator-South will be 28,000 square feet and, when full, will
University Technology Park at IIT - South
Landscaping MD 36 to Garrett County Line
Architectural Services - A/E Svcs. (Incl Landscaping Interior)
COMMUNITY ACTION AGENCY OF OKLAHOMA CITY, AND OKLAHOMA/CANADIAN COUNTIES, INC.
ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act. Staff will received cost of living adjustments and a temporary pay increase to ensure that compens
The ARRA award has allowed Child Care Associates to fund a variety of activities for both our Head Start and Early Head Start programs.  These include enhancement of staff compensation, improvement of staff qualifications, and improvement of pr
NORTHWEST ARKANSAS HEAD START HUMAN SERVICES INC
ARRA Cost of Living Adjustment(COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start .  Head Start promotes the school readiness of low-income children through the pr
Early Childhood COLA and Quality Improvement ARRA
Head Start/Early Head Start - provide cost of living salary adjustments and associated benefits to Head Start staff members, materials and supplies for program operation, and stipends for training.
Cola salary adjustments, classroom materials
Temporary 1.84% COLA:  Plaquemines Parish Head Start will use the temporary 1.84% COLA funds to give all Head Atart employees a pay raise for one school year.  Quality Improvement Funds:  Staff training is an area of high priority.  Funds will
Plaquemines Parish School Board Head Start
This grant awards a cost -of-living-adjustment(COLA) increase of 1.84% in the amount of $14,369 for Head Start.  This action also awards quality improvement funds of $45,351 for Head Start.
CHILD DEVELOPMENT COUNCIL OF ACADIANA INC
Cost of living adjustment of 1.84% and quality imporvement funds for Head Start and Early Head Start.  These funds are abligatged to pay staff salaries  within the twelve months.
B11 - The job positions ended 6-5-10, the school fiscal year ended 8-31-10; therefore the last reporting period was after the new school fiscal year began. In order to continue 3 out of 4 of these positions; the salaries of these positions were
All Other Miscellaneous Schools and Instruction
NORTHCENTRAL ARKANSAS DEVELOPMENT COUNCIL (NADC), INC.
To provide cost of living increase of1.4 percent in salary for 54 employees. To extend the work day from 4 hours to 5 hours per day for 17 classroom aides. To hire one full time specialist. to improve health and safety conditions at 14 Head sta
ARRA Supplemental Funds for Cost of Living Adjustments and one time needs to enhance the quality of services for staff, children and families
This award provides for the ARRA cost of living adjustment and the quality improvement funding consistent with the provisions of section 640(A)(5) of the Head Start Act for the Head Start Program and/or Early Head Start Program. Head Start prom
SOUTH PLAINS COMMUNITY ACTION ASSOCIATION, INC.
This action awards a COLA increase of 1.84% that goes to staff salaries and fringe. It is obligated over a 12 month period. This action also awards QI funds which are available to be obligated over the entire project period. The QI funds are us
COLLEGE STATION INDEPENDENT SCHOOL DISTRICT
ARRA COLA  and QI funding consistent with the provisions of Section 640(a)(5) of the Head Start Act
ST. MARTIN -IBERIA -LAFAYETTE COMMUNITY ACTION AGENCY (SMILE
This award provided funding for ARRA Cost of Living Adjustment (COLA) and Quality Improvement consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start and/or Early Head Start program. Head Start provide early
SMILE Head Start/Early Head Start Program
Head Start ARRA COLA and Program Improvement
ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640 (a) of the Head Start Act
COOKSON-HILL COMMUNITY ACTION FOUNDATION INC
HEAD START FUNDS ARE AWARDED UNDER THE AMERICAN RECOVERY AND REINVESTMENT ACT. HEAD START FUNDS ARE AWARDED UNDER CAN NO. 2009GO6022. THIS AWARD:(1.) COST OF LIVING (COLA) INCREASE OF 1.84% IN THE AMOUNT OF $60,871. (2.) QUALITY IMPROVEMENT FUN
This award provides for ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 604(a)(5) of the Head Start Act fro the Head Start and Early Head Start program.  Head Start promotes the s
ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5)of the Head Start Act.The Quality Improvement Funding was used for the Head Start Program in Caddo Parish. The agency is p
HIGHLAND COUNTY COMMUNITY ACTION ORGANIZATION INC
$26,469 is being used to give each Head Start employee a 1.84% temporary cola. $78,231 is being used to hire 1 center aid to float between centers and class rooms to help. Plus, Family Service Workers are picking up 4 hours per week to make the
Head Start Full Year Part Day Full Year Full Day Handicapped Training & Tech Assist
HEAD START:  FULL YEAR PART DAY HANDICAPPED TRAINING AND TECHNICAL ASSISTANCE
GARRETT KEYSER BUTLER HEAD START PROGRAM
ARRA Cost-of-Living Adjustments (COLA) and Quality Improvement Funding consistent with the provisions of Section 640 (a)(5) of the Head Start Act. Head Start promotes the school readiness of low-income children through the provision of comprehe
ILLINOIS VALLEY ECONOMIC DEVELOPMENT CORP
This award provides ARRA cost of Living Adjustment and Quality Improvement Funding consistent with the provisions of Section640(a)(5) of the Head Start Act for the Head Start and/or Early Head Start program. Head Start promotes the school readi
Racine/Kenosha Community Action Agency's grant award provided for ARRA cost of living adjustments (COLA) to Head Start staff and quality improvement efforts specific to R/KCAA's Head Start Program, consistent with the provisions of Section 640
ARRA Cost of Living (COLA) and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act
Head Start ARRA Cost of Living (COLA) and Quality Improvement (QI) funding award serving 626 income eligible children and their families in full-time, extended-day, and part-time programs in Kalamazoo County, Michigan.  Head Start is a Federall
This award provides for ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act  for the Head Start and/or Early Head Start program. Head Start promotes th
This awards provides for ARRA Cost of Living (COLA) and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start program on Gallia and Meigs Counties in Ohio. Head Start promotes t
The Early Head Start program at Hopewell Center, Inc.  provides family centered services for low-income families with very young children (pre-birth to thrity-six months) to promote the healthy development of the children and families.  EHS ser
ARRA Cost of Living Adjustment (COLA) and Quality Improvement Funding consisent with the provisions of Section 640(a)(5) of the Head Start Act for the Early Head Start program. Early Head Start promotes the healthy development of children (pre-
ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act.  The purpose of this funding is to increase the compensation and benefits of staff through a cost
Head Start ARRA Expansion-This award provides for ARRA Head Start Expansion funded to serve 51 children.  The Head Start program provides family-centered services for low-income families with three(3) year old children to promote the healthy de
1. PROJECT: Head Start ARRA Expansion 2. Number of Children Served: 20 children in Harrison County; 15 Children in Spencer County. 3. Program Options offered: Home Base option for Harrison County; Center Base option for Spencer County. 4. Count
NATIONAL CENTERS FOR LEARNING EXCELLENCE, INC.
ARRA Head Start Expansion. this involves providing Head Start services to 40 Head Start eligible children and their families at our Waukesha center. We are fully enrolled.
These funds will allow Lifelink to expand Head Start services to an additional 146 children and to expand Early Head Start services to 60 infants, toddlers, and pregnant women.  This includes start up costs, prorated operations and training, an
This award provides for ARRA Head Start Expansion funded to serve 100 children in Marion County.  The Head Start program provides family and child centered services for low income families with preschool children (3-5) to promote school readine
US-60; Timber Mountain (MP 278.8) to Seneca (MP 286.4)
Funded short fall in HUD rental assistance for this property
The purpose of this ARRA award is to ameliorate prior budget reductions.  Cumulative under funding of this 5-yr award led to the deferment of equipment replacement, preventive maintenance, projects and a reduction in DC magnet operations.  The
National High Magnetic Field Laboratory Renewal
Extension of water, sewer, and streets to 40.7 acres of the Richland Center North Industrial Park, Richland Center Wisconsin
Infrastructure for a 30.2 acre Village-owned industrial park including:  1,388 ft of 24-foot roadway, and associated storm water improvements; 2,090 ft of six and ten-inch water main and appurtenances; and 2,337 ft of six and eight-inch sanitar
businesses associated with the Flagship Enterprise Center.  Purpose: Economic stimulus through the creation of new businesses with resultant job and market creation.
Flagship Accelerator Building/Economic Adjustment (ARRA)
None of the above, unknown or unclassified
SR-69; I-17 to Big Bug Creek (1st Bridge)
Non-Personal Services for the Deployment, Operation, Maintenance, Repair, and Support of the US Geological Survey's Global Seismograph Systems.  Provide upgrade services of 20-23 Global Seismological Network sites between 15 July 2009 and 30 Se
USGS Tunison Lab Fire Alarm Fire Sprinkler Upgades; Courtland, New York
USGS National Wildlife Health Center Fire Alarm Fire Sprinkler Upgades - Madison, Wisconsin
Project Name:  Head Start Cost of Living and Quality Improvement (ARRA) Number of Children to be served: 489 Program Options Offered: Full day center-based Service Area:  Area within the boundaries of Lubbock ISD  Head Start promotes the school
This award includes a Cost of Living Adjustment (COLA) and Quality Improvement (QI) funding consistent with the provisions of Section 640(a)(5)of the Head Start Act.
JEFFERSON COMPREHENSIVE CARE SYSTEM, INC.
This award provides ARRA Cost of Living Adjustments and Quality Improvement Funding that is in harmony with the provisions of 640(a)(5) of the Head Start Act for Head Start and/or Early Head Start programs. Head Start elevates the school readin
This award provides for ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start and Early Head Start program. Head Start promotes the sc
Head Start/Early Head Start ARRA COLA & QI
Head Start Quality Improvement and COLA (ARRA)Delta Community Action Head Start will increase all current Head Start staff salaries by 1.84%. It will pay $20.00 per month to offset increased health insurance cost for the employee.  This money w
This award provides for ARRA COLA and Quality Improvement funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start and Early Head Start programs.  Head Start and Early Head Start promote the school re
MOUNT PLEASANT INDEPENDENT SCHOOL DISTRICT
West Feliciana Parish Schools Head Start
ARRA Cost of Living Adjustment and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act.  Scurry Community Services provides a full-day, full-year Head Start and Early Head Start program for chil
CHILD AND FAMILY SERVICES INC, OF LEA COUNTY
HILL COUNTRY COMMUNITY ACTION ASSOCIATION, INC.
This award provides ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act. Head Start promotes the school readiness of low-income children through provis
ECONOMIC OPPORTUNITIES DEVELOPMENT CORP OF ATASCOSA KARNES & WILSON COUNTYS
Cost of Living increase for staff salaries and benefits. Program improvements to enhance quality and safety of Head Start environments.
COLA ($53,692) Ouality Improvement (197,656)
ST MARY COMMUNITY ACTION COMMITTEE ASSOCIATION
This award provides for ARRA Cost of Living Adjustment (COLA) and Quality Improvement Funding consistent with the provisions of Section 640(a) (5) of the Head Start Act for the Head Start program. Head Start staff salaries are consistently lowe
Terrell Independent School District Head Start - The grant awards funds made available to the Head Start program under the American Recovery and Reinvestment Act. Head Start funds are awarded under CAN No. 2009 G06R022.  This action awards a co
GREATER OPPORTUNITIES OF THE PERMIAN BASIN INC
ARRA, COLA,and Quality Improvement funding consistent with the provision with section 640 (a)(5) of the Head Start Act. 1.84% ARRA Salary increase and Quality Improvement.These must must be obligatged to pay staff salaries and fringes starting
This award provides for ARRA cost of living adjustment (cola), and Quality Improvement Funding for Head Start and Early Head Start program. The proposed spending in this area is necessary in order to provide our students with facilities that ar
ARRA COLA  and QI funds for Head Start/Early Head Start program.
This action awards a cost-of-living adjustment (COLA) increase of 1.84% in the amount of $47,673 for Early Head Start.  A portion of these funds must be obligated to pay for staff salaries over the 12-month period following the effective date o
wide concrete pathways around our playground to provide egress for disabled children and their families.  We also purchased tricycles, wagons and replaced much needed clasroom toys.
CROSSROADS YOUTH & FAMILY SERVICES, INC.
Head Start/Early Head Start ARRA Cost of Living Adjustment (COLA) and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act, in order to award required salary adjustments to staff; to provide educ
ARRA Cost of Living Adjustment and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act. Wewoka Public Schools Co-op Head Start serves 248 children in 15 classrooms across Seminole and Lincoln Co
This award provides for ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start and Early Head Start program. The Concho Valley Council
Salaries, Fringe, Playground Equipment and Classroom Supplies.
ARRA Head Start Expansion Grant This grant has allowed us to serve 35 previously unserved three and four year old children whose families? income places them at the poverty level or below.  The children are served in a full day, center based pr
STIMULUS OVERLAY-SR6- INTERSTATE 55 TO LAFAYETTE CO-EASTBOUND LANES ONLY
St. Louis City, Route 70 (Memorial Drive)
INCORPORATED RESEARCH INSTITUTIONS FOR SEISMOLOGY
The integrated observing systems that comprise the EarthScope Facility can be used to address fundamental questions at all scales, from the active nucleation zone of earthquakes, to individual faults and volcanoes, to the deformation along the
Collaborative Research: EarthScope Facility Operation and Maintenance (FY2008-FY2013) (USArray)
In this study, we will enter for the first time the main brine body below the thick ice of Lake Vida, east Antarctica and perform in situ measurements, collect samples of the brine column, and collect sediment cores from the lake bottom for det
Collaborative Research  Geochemistry and Microbiology of the Extreme Aquatic Environment in Lake Vida  East Antarctica
The AZ Bioscience Park is located within census tract 22 in the South Market of the federally-deignated Tucson Empowerment Zone/Enterprise Community.  This project involves the following:  Paving & Striping; all raod work includes sub grade pre
The project to be funded by this grant, the Digital Media Center @ the Tannery, consists of the rehabilitation of three historic buildings on the site of the former Salz Tannery and their conversion for use as a digital media and creative arts
Reroof 15 large warehouse bays at the Big Pasco Industrial Center in Pasco, WA to create or retain 496 jobs.
Big Pasco Industrial Center Nine Warehouse Bay and 6 Warehouse Bay Re-Roofing Project
North Brand Blvd street improvements between Truman Street and South City Limit.  Roadway pavement improvements include coldmilling of AC pavement, and construction AC surface course.  Concrete improvements include removal and replacement of si
FY2009 ARRA COLA/QI Award Description:  This award provided for Cost of Living Adjustments and Quality Improvements.   1. The Cost of Living Adjustments allowed for across-the-board increases in wages for our staff. Quality improvements include
HEAD START CHILD & FAMILY DEVELOPMENT PROGRAM INC
HAWKEYE AREA COMMUNITY ACTION PROGRAM, INC.
ARRA COLA and Quality funds will be utilized to establish a level 3 Early Childhood licensed teacher. ARRA funds will support a 1.84% COLA increase. Technology support with laptop purchases for lead teachers.
ARRA cost of living adjustment (Cola), and Quality Improvement Funding Consistent with the provisions of Section 640 (a)(5) of the Head Start Act.The ARRA cost of living adjustment (cola) was given to all the Head Start and Early Head Start emp
Head Start and Early Head Start Quality Improvement and COLA (ARRA)
Award Title = Head Start ARRA Expansion.  Award Description and Overall Purpose of the Award = Expand the number of Head Start children served by 17 additional children.  Expected Outcomes / Results = provide Head Start services to 17 additiona
ARRA Head Start Expansion Grant to serve 64 additional Head Start children and families in Pottawattamie County, Iowa. Head Start promotes the readiness of low-income children through the provision of comprehensive health, developmental and fam
Desoto County Rest Area - Site Improvements - I-55
US 61/49 Hospitality Station Improvments
The project will construct infastructure improvements(water, sanitary sewer, roads) for the expansion of the Roth Industrial Park to facilitate new business growth.
Economic Adjustment Assistance: ARRA/Infrastructure improvements for the Roth Industrial Park
East & West Washington St Sidewalk Improvements
HARCATUS TRI-COUNTY COMMUNITY ACTION ORGANIZATION
Award No. 05SE5005/01 HEAD START: FULL YEAR PART DAY HANDICAPPED    TRAINING & TECHNICAL ASSISTANCE ARRA Cost of Living Adjustment(COLA), and Quality Improvement Fuunding consistent with the provisions of Section 640(a)(5) of the Head Start Act
COUNCIL FOR ECONOMIC OPPORTUNITIES IN GREATER CLEVELAND
This award provides for ARRA  Cost of Living Adjustment(COLA) and Quality Improvement Funding consistent with the provisions of Section 640 (a) (5) of the Head Start Act for the Head Start and Early Head Start program.  Head Start promotes the
CINCINNATI-HAMILTON COUNTY COMMUNITY ACTION AGENCY
ARRA Cost of Living Adjustment (COLA) and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act. CAA requested one-time ARRA dollars to temporarily increase staff salaries and fringe benefits and
ARRA Cost of Living (COLA) and Quality Inprovement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act to supplement the regular Head Start Program.
Head Start Projects This award provides for ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start and/or Early Head Start program. Hea
ECONOMIC OPPORTUNITY COMMITTEE OF ST. CLAIR COUNTY, INC.
JEFFERSON COUNTY COMMUNITY ACTION COUNCIL INC
Headstart serves 249 center based children for 4 days per week and for 6 hours per day. All Head Start sites are in operation for 32 weeks for children and 36 weeks for administrative teaching staff.Jefferson County CAC Headstart serves th city
COMMUNITY ACTION COMMITTEE OF PIKE COUNTY, THE
This award provides for ARRA Cost of Living Adjustment (COLA) and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start and Early Head Start program. Head Start promotes the sch
PICKAWAY COUNTY COMMUNITY ACTION ORGANIZATION
ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)serving 212 children in Ohio Pickaway County.  The Head Start program promotes school readiness by enhancing the social and c
SOUTH CENTRAL COMMUNITY ACTION PROGRAM INC
?	Hire Behavior Support/Fatherhood Specialist  ?	Increase the compensation and benefits of staff through a cost of living adjustment to improve the overall quality of the program.  ?	Permanently increase SCCAP Head Start  pay scale by 3.06% ?	O
HEAD START PROMOTES THE SCHOOL READINESS OF LOW-INCOME CHILDREN THROUGH THE PROVISION OF COMPREHENSIVE HEALTH, DEVELOPMENTAL AND FAMILY SERVICES.  HEAD START IS A FULL YEAR PART DAY SCHOOL PROGRAM THAT ALSO INCLUDES TRAINING AND TECHNICAL ASSIS
HEAD START/EARLY HEAD START ARRA COLA/QUALITY
CAN No. 2009 G05R022 Head Start: FY/PD Handicapped T&TA.  Head start staff  COLA increase pf 1.84% and quality improvement funds for both staff training/development, addition of staff psychologist position and supplies.
CLINTON COUNTY COMMUNITY ACTION PROGRAM INC
ARRA COST OF LIVING ADJUSTMENT(COLA AN QUALITY IMPROVEMENT FUNDING CONSISTENT WITH THE PROVISIONS OF SECTION 640 (A)(5)OF THE HEAD START ACT FOR THE HEAD START AND/OR EARLY HEAD START PROGRAM. HEAD START PROMOTES THE SCHOOL READINESS OF LOW-INC
Head Start promotes the school readiness of low-income children through the provision comprehensive health, developmental and family services.  We serve 467 federal children and 102 state children.  We offer 3 program options - home base, cente
Award Title: Head Start & Early Head Start: Full Year Part Day Training and Technical Assistance. This award provides for ARRA Cost of Living Adjustment, and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the
ROSS COUNTY COMMUNITY ACTION COMMISSION INC
This award provides for ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start Program. Head Start promotes the school readiness of low
AREA FIVE AGENCY ON AGING AND COMMUNITY SERVICES, INC.
The American Recovery and Reinvestment Act (ARRA)Request for Funding for Quality Improvement for Area Five Agency Head Start.  In utilizing ARRA funds to the best possible end, Area Five will replace the HVAC system, and update electrical compo
Head Start:Full year part day handicapped training & technical assistance. Funded to promote school readiness of low-income children through the provision of comprehensive health, developmental and family services to 314 low-income children, of
Head Start: Full year part day handicapped training and technical assistance.
Cost of Living adjustment and quality improvement funding consistent with the provisions of Section 640 (a)(5) of the Head Start Act.  Head Start promotes the school readiness of low-income children through the provision of comprehensive health
PEORIA CITIZENS COMMITTEE FOR ECONOMIC OPPORTUNITY, INC.
This award provides for ARRA Cost of Living Adjustment and Quality Improvement Funding consistent with the provisions of Section 640(a)(5)of the Head Start Act for the Head Start and Eraly Head Start Programs. Head Start promotes the school rea
Head Start: Full year Part day Handicapped Training and Technical Assistance
This award provides for ARRA Cost of Living Adjustment (COLA) and Quality Improvement Funding consistant with the provisions of Section 640(a)(5) of the Head Start Act for Head Start and Early Head Start programs.  Head Start and Early Head Sta
Costof living and Quality Improvement Funding consistent with the provision of Section 604 (a)(5) of the Head Start Act. Awarded to Celina city Schools Head Start program serving eligible children throughout Mercer County. Head Start is funded
MIAMI VALLEY CHILD DEVELOPMENT CENTERS, INC.
Head Start Quality Improvement and COLS (ARRA)MVCDC is serving 2,429 Head Start children and 102 Early Head Start children with this grant. We offer the Full-year/full-day option, the Full-year/part-day option the Part-day/double session option
Funding is being used to increase salaries, provide services to expecting mothers, curriculum training for staff and mothers.  Purchase library books and materials and include training for staff and parents on hte use of materials that is age a
Community Link,Inc. Early Head Start (EHS) was awarded a discretionary grant of $35,165 by ARRA.  The grant included Cost of Living adjustment increase of 1.84% and quality improvement funds of $29,183.  The EHS program is a full-year home-base
CROSSROADS: LAKE COUNTY ADOLESCENT COUNSELING SERVICE
Our program mission continues to promote growth of early childhood services through meaningful collaboration.  By partnering our federal Early Head Start funding with other state and county funding resources, we bring a fully integrated and hig
Head Start Quality Improvement and COLA. Funds to provide Cost of Living Adjustment to Head Start staff salaries and Quality Improvement to improve our services to children.
The Head Start Expansion (ARRA) program supports Early Head Start services for 300 additional infants, toddlers and pregnant women and Head Start services for 290 additional children. In addition to services, funding also supports startup costs
Head Start Expansion ARRA.   Services for 2 classrooms (double sessions) for 68 children age 3-5 years.  Continuation of year 1.   All expansion slotted children receive the exact same service level as the regular programming per original grant
This award provides for ARRA Head Start Expansion funding to serve 44 children.  The Head Start Program promotes the school readiness of low income children through the provision of comprehensive health, developmental and family services. Our p
Project Description: This award provides for ARRA Head Start Expansion funds to provide comprehensive child development services to an additional 32 economically disadvantaged preschool children (ages 3 to 5) and their families in Monroe County
University of Wisconsin Oshkosh Head Start ARRA Head Start Expansion project offers Head Start services to 23 preschool children three years to five years of age who live in families with very low-incomes as defined by the Head Start Performanc
Head Start ARRA Expansion project award provides full day, full year Head Start services to 18 children, ages three to five, in full day, full year center based program option. Project period began 9/30/2009; children served in this program wou
US 60 Tomahawk TI (MP 197) - Apache Junction
US 60 Goldfield TI (MP 198) - Apache Junction
Project Police Revitalization- purchase of police uniforms and equipment
EXIT 112 AT THE INTERSECTION OF I-65 AND HWY 245
Establishment of a micro loan revolving loan fund to be operated and maintained by ACCION Chicago, used for the purpose of lending and relending project funds as small business loans to borrowers located in Cook County for the overall purpose o
Supports the work to create access to the I35/I90 Business Park.  This Business Park will create jobs and tax base
Infatructure for 80 acre I35/I90 business park
USGS Great Lakes Science Center - Repair, Correct and Replace Electrical Distribution Service; Ann Arbor, Michigan
The ARRA award provides COLA adjustments and quality improvement funding consistent with the provisions of the Head Start Act: The funding ensures consistently and continuation of services.  Funds are designated for program improvement and deve
Head Start Quality Improvement and COLA (ARRA)  Cost-of-Living adjustment of 1.84% in the amount of $422,815 and quality improvement funds of $1,349,202.  The funds were utilized to retain qualified staff and improve quality services by acquiri
Grant was awarded to fund a temporary cost-of-living adjustment (COLA) increase for both Head Start and Early Head Start employees; provide quality improvement funds to improve compensation and qualifications/skills of educational personnel inc
Classroom Coverage Enhancement; Road to BA degree; Enrichment Classrooms; Crisis Intervention Training; Bilingual Educator Training; Quality Improvement for Facilities
GREEN COUNTRY BEHAVIORAL HEALTH SERVICES
This award provides for ARRA Cost of Living (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start and/or Early Head Start program.  Head Start promotes the school re
TWIN RIVERS COMMUNITY ACTION FOUNDATION INC
This award provides for ARRA Cost of Living Adjustment and Quality Improvement Funding for Head Start.  Head Start promotes the school readiness of low-income children through the provision of comprehensive health, developmental and family serv
The action awards a COLA increase of 1.84% in the amount of $51,965 and quality improvment funds in the amount of $32,279. COLA funds were awarded to increase the  hourly rate of all positions to attract and retain qualified staff. The quality
ARRA COST OF LIVING ALLOCATION AND QUALITY IMPROVEMENT FUNDING
LA SALLE COMMUNITY ACTION ASSOCIATION INC
This Head Start ARRA discretionary Grant has enriched the Head Start program in Catahoula, Concordia, LaSalle, Tensas, Grant and Caldwell Parishes in Louisiana. $66,979 of this award was used for a Cost of Living Adjustment (COLA) increase for
AWARD TITLE:HEAD START/EARLY HEAD START COLA/QUALITY IMPROVEMENT  THIS ACTION AWARDS FUNDING FOR EXISTING STAFF COST OF LIVING ADJUSTMENTS (COLA)IN THE AMOUNT OF 1.84% (76,495 HEAD START; 15,085 EARLY HEAD START) AND/PROGRAM QUALITY IMPROVEMENT
ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act. Vernon Parish Head Start serves 270 students in a part-day center-based environment 5 days a week
ARRA Cost of Living Adjustment (COLA)and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start and/or Early Head Start program.
ARRA cost of living adjustment (COLA) and Quality Improvement funding consistent with the provisions of Section 6409(a)(5) of the Head Start Act. Community Action Resource and Development, Inc. as Head Start and Early Head Start Progams.  We se
Stimulus funds for this award are to be used for the Plano ISD Head Start program, which serves pre-kindergarten children and their families.  A portion of the funds will be used to pay overtime salaries to help test children and register famil
COMMUNITY ACTION CORPORATION OF SOUTH TEXAS
This award provides a Cost of Living Adjustment (COLA) and Quality Improvement Funding. The Head Start program provides a quality education for low-income children in an effort to prepare them for school. Our program provides services to 1,306
ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5)of the Head Start Act.  Head Start promotes the school readiness of low-income children through the provision of comprehen
Enhancing School Readiness Through Comprehensive Services
ARRA COST OF LIVING ADJUSTMENT (COLA), AND QUALITY IMPROVEMENT FUNDING CONSISTENT WITH THEPROVISIONS OF SECTION 640(A)(5) OF THE HEAD START ACT.
Quality Improvement Funding for the Region 9 Head Start Program has been used to  better serve eligible Head Start Children and to promote school readiness for over 700 of low-income children in 4 counties of North Texas.
PARENT/CHILD INCORPORATED OF SAN ANTONIO & BEXAR COUNTY
Inaccordance with guidance in Program Instruction, Log No. ACF-PI-HS-09-06, dated 04/02/2009, $28,361.00 is to provide a 1.84% American Reinvestment and Recovery Act (ARRS) cost-of-living increase (COLA) across the board to all Early Head Start
VOLUNTEERS OF AMERICA OF NORTH LOUISIANA
ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Sections(a)(5) of the Head Start Act.  Funds will be used to conduct the Early Head Start Enhancement Project.  Sixty-Eight(68) children wi
ARRA Cost of Living (COLA) and Quality Improvement Funding consistent with provisions of Section 640(a)(5) of the Head Start Act
ARRA 2009 funds allocated to provide the following: 1) COLA increase of 1.84% in the amount of $15,033 and 2) QI funds of $51,398
This award provides for ARRA HS Expansion funding to serve 17 age and income eligible 3 year old children.We have 17 new children enrolled for the  2011-2012 school year which began on August 15th.Eight out of the 17 new children transitioned f
Head Start promotes the school readiness of low-income children through the provision of comprehensive health, developmental and family services.  HCDE Head Start  received Expansion(ARRA) Year 1-2 to provide full day  Head Start services to 80
The ARRA Head Start Expansion provides for the funding of 200 children ages 3-4 years for the center based services program option.   Head Start promotes the school readiness of low-income children by providing them with comprehensive health, d
Spatial and temporal integration of carbon and mineral fluxes: a whole watershed approach to quantifying anthropogenic modification of critical zone carbon sequestration. To quantify the impacts on the global carbon cycle of humans as geologica
CZO: Spatial and temporal integration of carbon and mineral fluxes: a whole watershed approach to quantifying anthropogenic modification of critical zone carbon sequestration
Pearl St.  from State St. to Jefferson St. (6089)(0.24 mi.), Commerce St. from State St. to Jefferson St. (6090)(0.24 mi.), Rankin St. from Orleans St. to Jefferson St. (6092)(0.38 mi.), Washington St
Highway Infrastructure Investment - Highway resurfacing - From funding for use in any Area (flexible) and from funding for use in Areas with population equal to or less than 200,000
SR 13 beg. 4.7 mi. north of the Marion CL then run north to US 84
COLA-ARRA-$24176.00-provides an additional 2.9% increase in the hourly rate of pay for all full-time and part-time employees.  Quality Improvement Funds-ARRA-$72941.00 increases the hourly rate of pay for educational staff and family service wo
COUNCIL OF 3 RIVERS AMERICAN INDIAN CENTER
Project Title: 2009 American Recovery and Reinvestment Act Head Start/Early Head start COLA and Quality Improvement Funds. Project Description: This award provided ARRA Cost of Living Adjustment(COLA) and Quality Improvement funding consistent
This award provides for ARRA Cost of Living Adjustment and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start and Early Head Start program.  Head Start promotes the school readiness of low income c
This award provides for Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start program.  Head Start promotes the school readiness of low-income children through the provision of
Lee County School District/Lee County Head Start
Head Start 2009 ARRA COLA and Quality Improvment Funding. Temporary salary increase for staff,fringe benefits, field trips, and staff in-service.
Head Start Quality Immprovement and  COLA (ARRA)
This award provides for ARRA, Cost of Living, and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start / Early Head Start program.  Head Start promotes the school readiness of
Richmond Public Schools Early Head Start / Head Start
1) American Recovery and Reinvestment Act (ARRA).  The award provides for a 3.06% permanent COLA and 1.84% temporary COLA as well as for quality improvement funding.  Baltimore City Head Start's  ?Quality Improvement? (QI) funds address three a
Baltimore City Head Start and Early Head Start ARRA COLA Quality Improvement Funding.
This award provides for ARRA Cost of Living Adjustment (COLA) and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start program. Head Start promotes the school readiness of low-
Parent Child Development Corporation is using the ARRA funding to:  1. Ensure compensation is adequate to attract and retain qualified staff to improve overall program quality,  2. Improve staff qualifications and assist with career development
Head Start 2009 ARRA COLA Quality Improvement funding will be used to increase Head Start Salaries and Fringe Benefits for 226 staff over a 12 month period and will be given in the form of a stipend in addition to their regular salaries.  We wi
Allegheny County/Alleghey Intermediate Unit Head Start Coat of Living Adjustments (COLA) and Quality Improvement (QI) Funds
Bucks County Head Start, Inc. serves 636 3-5 year old children and families that meet the federal poverty income guidelines and reside in Bucks County, Pennsylvania that qualify for the program. BCHS, Inc. used the ARRA cost of living and quali
This award provides ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of section 640(a)(5) of the Head Start Act for the Head Start program.  Head Start promotes the school readiness of low-in
Head Start 2009 COLA & Quality Improvement
GARRETT COUNTY, MARYLAND, COMMUNITY ACTION COMMITTEE, INC.
This award provides for ARRA Cost of Living Adjustment (COLA) and Quality Improvement Funding consistent with Section 640 (a) (5) of the Head Start Act for the Head Start and Early Head Start program.  These programs promote school readiness of
Funds are to provide a 2.5% increase to current employee salaries for a duration of one year; assist in degree attainment in order to meet staff qualification requirement in the head Start Act; staff development; transportation service delivery
Head Start COLA & ARRA Quality Improvement
Community Action Council of Howard County
Head Start 2009 ARRA Cost of Living Adjustment (COLA)Quality Improvement funding consistent with the provisions of Section 640(a)(5) of the Head Start Act.  163 Head Start children served in Somerset County would benefit by receiving a higher q
HEAD START 2009 ARRA COLA QUALITY IMPROVEMENT SALARIES FOR ADVANCEMENT AND CONTRACT EXTENTIONS, FRINGE BENEFITS FOR STAFF, WE HAVE A TEACHER THAT WAS UPGRADED AND A DIRECTOR WHO'S CONTRACT WAS EXTENDED, WE ALSO HAVE TWO POSITION THAT ARE POSSIB
HEAD START 2009 ARRA COLA AND QUALITH IMPROVEMENT
ARMSTRONG COUNTY COMMUNITY ACTION AGENCY
Head Start 2009 ARRA COLA Quality Improvement Funding.  This Award funds a COLA increase in salaries and wages of 1.84% in the amount of $89,704 for Head Start and $9,300 for Early Head Start.  In addition Quality Improvement funds are awarded
Head Start 2009 ARRA COLA and Quality Improvement Funding.
This award provides for ARRA Head Start expansion to serve 32 additional children for two years (From 9/30/09 - 9/29/11). The Head Start program promotes the school readiness of low-income children through the provision of comprehensive health,
SR 1 2.878 miles N SR 8 to Bungee Corp Turnoff
painted interior of apartments, replaced bathroom heaters, replaced ranges & refrigerators, replaced a few storm doors, replaced mini blinds where needed and hot water heaters.
Renovation and expansion of an existing 53,000 square foot campus building to house programs including machining, welding, HVAC. The facility has a complete first floor and partial second floor. The scope of work will construct and finish  the
SOUTHERN CAROLINA REGIONAL DEVELOPMENT ALLIANCE
The project will construct off site rail facilities in the South Carolina Advanced Technology Park in Barnwell, South Carolina. The project will result in the creation of 52 permanent jobs and a capital investment of $72,000,000. The purpose of
Secondary Smelting, Refining, and Alloying of Nonferrous Metal (except Copper and Aluminum)
The Georgia Ports Authority was awarded an EDA American Recovery Program Public Works and Economic Development Facilites Grant for the realignment of Container Berths 4, 5, and 6 which will allow the container stacks to be parallel to the dock,
Economic Adjustment Program / Container Berth Realignment
Grant to support a water and sewer improvement project in Dorchester County, South Carolina.
Economic Adjustment Program/Water and Sewer Improvements
Head Start COLA / Quality Improvement Funds shall be used for the following:  1.)  1.84% COLA used to pay salary benefits to upgrade clerk's position (employed for 10 years) to secretary.  The funds will also be used to pay a portion of the fri
This award provides ARRA COLA and educational incentive for 33 employees working in the Early Heast Start program This award also provided new playground equipment for an average of 175 children per month in the Early Head Start program.
MIDDLE GEORGIA COMMUNITY ACTION AGENCY, INC., THE
The Quality Improvement/COLA award has been allocated to serve 2120 Head Start and Early Head Start students in Broward County, FL.  The District?s Head Start Program serves 2040 students in a center-based setting; the Early Head Start Program
OKALOOSA COUNTY HEADSTART CHILD DEVELOPMENT INC
Award Title: American and Reivestment Act  Awards a cost of living adjustment increase of 1.84% in the amount of $36,783 for Head Start and $11,897 for Early Head Start.  Funds are obligated to pay staff salaries and fringe.  The award is also
ARRA Cost of Living Adjustment (COLA) and Quality Improvement Funding consistent with the provisions of section 640(a) (5)  of the Head Start Act.
BIG SANDY AREA COMMUNITY ACTION PROGRAM INCORPORATED
The ARRA funding was granted to our agency for the cost of living increase and for quality improvements through out our program design.  The structure of the grant allows for increases in grantee and delegate staff salaries in order to retain q
ARRA Cost of Living Adjustment(COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act in Henderson, Polk and Transylvania Counties.
ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act  All Head Start employees received a 1.84% temporary increase in their base pay.  Educational assis
JOHNSTON LEE HARNETT COMMUNITY ACTION INC
ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a) (5) of the Head Start Act. This funding award will aid our Head Start progam in helping to pay for health insurance for our
Head Start ARRA COLA and Quality Improvement
1.  ARRA Cost of Living Adjustment(COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act.
MIDDLE KENTUCKY COMMUNITYACTION PARTNERSHIP INC
This award provides for ARRA Cost of Living Adjustment and Quality Improvement funding consistent with the provisions of Section 640 (a) (5) of the Head Start Act for the Head Start program.  Our program provides comprehensive services in an ef
YADKIN VALLEY ECONOMIC DEVELOPMENT DISTRICT INC
Head Start Quality Improvement and COLA (ARRA) Provide Assistance to 120 pre-school students of which 13 are dual language. The programs are center-based and serve Ashland, Boyd County, Kentucky. The purpose of the Head Start program is to prov
COLA Project - 1. Fund an increase in the contributions to the retirement plan.  2. fund increased costs of building operations.
The Community Action Committee, Inc. of Chambers-Tallapoosa-Coosa Head Start serves 528 children. The program seeks to provide programming that will enhance children?s growth and development in preparation for later academic and social pursuits
This award provided COLA for Head Start and Early Head Start staff and Quality Improvement for Head Start centers.This award restored contracted services taht were previously cut due to budget restraints, restored one center to full year, resto
HEAD START AND EARLY HEAD START (ARRA). FISCAL YEAR 2009-2010-COLA INCREASE/QUALITY IMPROVEMENT FUNDING/T/TA. HEAD STRT AND EARLY HEAD HEAD START SERVES 460 CHILDREN FROM LOW-INCOME FAMILIES IN BEAUFORT AND JASPER COUNTY. THE PROGRAM PROVIDES C
COMMUNITY ACTION AGENCY OF BALDWIN ESCAMBIA CLARKE MONROE CO
This award provides for ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the     provisions of Section 640(a)(5) of the Head Start Act for the Head Start and/or Early Head Start program. Head Start promotes
CHESTERFIELD-MARLBORO COUNTY ECONOMIC OPPORTUNITY COUNCIL, INC.
TO PROVIDE COST OF LIVING ADJUSTMENT (COLA), AND QUALITY IMPROVEMENT FUNDING CONSISTENT WITH THE PROVISIONS OF SECTION 640(A)(5) OF THE HEAD START ACT.
Head Start 2009 - 2010 ARRA/COLA and Quality Improvement Funding.  This project serves 656 children at four Head Start sites in the cities of Clarksdale, Jonestown, and Friars Point, Mississippi. These cities are located in the county of Coahom
Air-Conditioning and Warm Air Heating Equipment and Commercial and Industrial Refrigeration Equipment Manufacturing
This award provides for ARRA cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start and/or Early Head Start Program.  Head Start promotes th
Head Start/Early Head Start Cola, Qulaity Improvement to low income children and their families. Cola Activities: The agency shall provide a 1.84% Cost of Living Adjustment in salaries and fringe benefits to eligible employees. Quality Improvem
COLA ACTIVITIES:The agency provided 2.426% Cost of Living Adjustment in salaries and fringe benefits to Head Start Employees and 2.112% to Early Head Start employees for a twelve month period. Quality Improving Funding was utilized for the foll
COASTAL GEORGIA AREA COMMUNITY ACTION AUTHORITY
Funds shall be used to provide: 1. a 1.84%COLA (cost of living adjustment)to 186 Head Start staff employed during the period of July 1, 2009 through June 30, 2010; 2. the agency shall provide an increase in the fringe benefits consistent with
This award provides for ARRA Cost of Living Adjustment(COLA) and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start and/or Early Head Start program.  Head Start promotes the
Head Start ARRA Cost of Living Adjustment and Quality Improvement Funding consistent with the provisions of section 640(a).  Award utilized to provide staff training, improve physical environments, support staff in family services and finance a
ARRA Head Start Expansion grant provides comprehensive Head Start child development, health, and family support services for 81 children and their families in the Kentucky counties of Daviess, Hopkins, Christian, and Todd in grantee's service a
EXPAND HEAD START PROGRAM BY 2 CLASSROOMS TO SERVE AN ADDITIONAL 34 CHILDREN IN LENOIR COUNTY, NC.  FUNDS REQUESTED FOR HIRING STAFF, TRAINING, EQUIPMENT AND SUPPLIES TO SET UP CLASSROOMS, OFFICE AND PLAYGROUND AREAS AS WELL AS MAINTAINING THE
This award provides funding to Douglas Cherokee Head Start Program to expand the program to provide comprehensive Head Start services to 34 low income children (ages 3 & 4)and their families in Sevier and Hamblen Counties in rural upper east Te
Report Status - 50% or more complete. This award is a two year award. This report is not a final report. Award Title: ARRA - Head Start. Award Description: The objective of the Head Start programs to promote the school readiness of low-income p
ARRA Head Start Expansion. Through this grant, we have added 154 children to our Head Start roster. All of these children are served in a center-based program, 10 hrs. per day, 5 days per week. These programs are scattered throughout Palm Beach
Head Start 2009 ARRA Expansion Funding - This award is for 4 additional Head Start classrooms in Morgan County in North Alabama. These classrooms will have 20 preschool age children for low-come families. The basic goal for Head Start is to pro
Award Type: Service ARRA Head Start Expansion Serve an additional 41 children in Aiken County for whom we can expand services. Provide school readiness of low-income children with high quality child development & family support services.
HEALTH AND HUMAN SERVICES, MAINE DEPARTMENT OF
ARRA-ASC-HAI - This initiative will significantly expand the awareness of proper infection control technique among ASCs and SAs, increase the extent to which infection control deficiencies are both identified and remedied, and prevent future se
Congress, generally, no additional specification available
Head Start ARRA COLA and Quality Improvement Funds The action awards a cost-of-living increase of 1.84% for Head Start staff and approval of funds for minor renovations for two facilities , Sheffield and LaPorte.
The Program will utilized 50% of the allocation to improve the compensation and benefits of Head Start personnel as listed in Section 640(a)(5): to ensure adequate compensation to attract and retain staff; to improve staff qualifications and as
PY09 Head Start American Recovery and Reinvestment Act (ARRA) funding: temporary COLA 1.84% + Quality Improvement
NEWTON COUNTY SPECIAL SERVICE CORPORATION INC
ARRA Cost of Living Adjustment (COLA) and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act.This funding will enhance the overall quality of the Early Head Start Program by increasing wages an
ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding Consistent with the provisions fo Section 640(a)(5) of the Head Start Act.
This award provided for ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start and/or Early Head Start program. Head Start promotes the
HEAD START EXPANSION (ARRA) AWARD SERVING FORTY (40) ADDITIONAL CHILDREN USING A YEAR-ROUND LOCALLY DESIGNED OPTION (LDO) VISITING TEACHER MODEL THAT IS SUPPLEMENTED BY EMERGENCY CLASSROOM ASSISTANTS, A FAMILY SERVICE WORKER, AND A CLERICAL SUP
Head Start ARRA Expansion.  This award provides for ARRA Expansion funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start program.  Head Start promotes the school readiness of low-income children th
This grant awards funds made available to the Webb County Commissioners Court Head Start program under the American Recovery and Reinvestment Act to expand Head Start services to sixty eight children in Webb County.
1.ARRA Head Start Expansion/Delta Head Start 2. 54 children 3.center based option 4.  McClain, Garvin, and Stephens counties 5.  Head Start promotes the school readiness of low-income children through the provision of comprehensive health, deve
CENTER FOR SEVERE WEATHER RESEARCH INC, THE
Intellectual Merit: Under this Cooperative Agreement the Principal investigator will provide as a national facility a three-system ground-based mobile radar fleet, the Doppler On Wheels (DOWs). The three systems include two mobile X-band Dopple
Improvements to a multi-use dock, including replacing decayed pilings with steel pilings, and installing a fender system.
Construction of the Eureka Fisherman's Terminal Building
The overall purpose of the ARRA funds is to enhance our program services for children and families.  To enhance our Early Head Start and Head Start services, our program has developed a number of projects, which includes improving staff compens
Compensation, Personal Development, Training & Playground Upgrades
COMMUNITY ACTION PARTNERSHIP OF LANCASTER AND SAUNDERS COUNTIES
Head Start Quality Improvement and COLA (ARRA); Total Number of Children Served-644; Program Options-Early Head Start Home-Based, Early Head Start Full-Day Center-Based, Head Start Part-Day Center-Based, and Head Start Full-Day Center-Based; Co
The overall purposes and intended outcomes included: more hours of preschool services each day for children in a Head Start classroom, more fully funded family development home visitation services for 20 Head Start families, two improved toddle
SOUTHEAST KANSAS COMMUNITY ACTION PROGRAM HOUSING, INCORPORA
HEAD START ARRA EXPANSION This award provides Head Start ARRA Expansion funding to serve 15 children in the center-based program option.  Head Start promotes the school readiness of low-income children through the provision of comprehensive hea
Award Title: Head Start ARRA Expansion.  ARRA Supplemental Funding : Provide Head Start services  for 145 slots for families in the Jackson, Clay, and Platte counties in Missouri..  The year two funds will be used to continue providing comprehe
Phase IV Improvements to the Jamestown-Verrazano  Bridge No. 800
Federal project 0800010, involving grading, removal and replacement of pipe, curb and gutter and  sidewalk, and miscellaneous work at various locations on 0.38 miles on WYO 151, beginning at  reference marker 3.72 in the town of LaGrange, in Go
Highway Infrastructure Investment - Bridge rehabilitation, no added capacity (no added travel lanes) - From funding for use in any Area (flexible)
Bridge Deck Replacement Program I-80 EB & WB over Berkshire Valley Road, Construction
I-80 Corridor Bridge Painting, Construction, Interstate Bridge painting Contract No. 2
Highway Infrastructure Investment - New bridge - From funding available for use in any Area (flexible)
Collaborative Research: Physics Based Modeling of Blue Jets. This project will focus on further development of a model of upper atmospheric phenomena known as Blue Jets, Blue Starters, and Gigantic Blue Jets. Blue Jets are narrow cones of blue
Collaborative Research: Physics Based Modeling of Blue Jets
Volcanoes are places where molten rock erupts on the surface of the Earth; they are both major natural hazards and fascinating targets for scientific study because they are messengers from the interior of our planet, where melting of rocks take
Collaborative Research:  Solution Thermodynamics of Igneous Pyroxenes and Garnets
Drexel University and Penn State University are partnering for a second round of WATERs testbed proposals concerning the Susquehanna River Basin Hydrologic Observatory System (SRBHOS).  While the first phase concentrated on the establishment of
Collaborative Proposal:  WATERS:  Evaluating Community Models and Observation Networks Under Uncertainty within the Susquehanna River Basin
'Geodetic deformation across the Himalaya reflects primarily locking of the Main Himalayan Thrust (MHT) fault from the surface to a depth of about 15-20km. Local seismic monitoring has revealed clustered seismicity that is probably driven by s
Spatio-temporal variations of seismicity and coupling in the Himalaya
The Research and Training Grant 'Analysis and Applications' has as its aim the increase of the numbers of US students interested in mathematics and, more specifically, in fields related to mathematical analysis.  The grant provides training fun
Collaborative Research: Measurement of Cosmic Ray Response Functions for an Ice Cherenkov Detector    We determined a complete set of cosmic ray response functions for the ice Cherenkov detector used in the surface air shower array that is part
COLLABORATIVE RESEARCH: MEASUREMENT OF COSMIC RAY RESPONSE FUNCTIONS FOR AN ICE CHERENKOV DETECTOR
The GBASE project (GeomicroBiology of Antarctic Subglacial Environments) is one of three research components of the WISSARD (Whillans Ice Stream Subglacial Access Research Drilling) integrative initiative that is being funded by the Antarctic I
Collaborative Research: GeomicroBiology of Antarctic Subglacial Environments (GBASE) Beneath the Mercer and Whillans Ice Streams
Persistent organic pollutants (POPs) persist in the environment, undergo long-range atmospheric transport to polar regions, accumulate in biological tissues, biomagnify (increase in concentration with trophic level) in food webs, and cause adve
Collaborative Research: Persistent Organic Pollutants in the Antarctic Marine Food Web: Impact of Climate Change and Insights into the Feeding Ecology of Apex Predators.
Marine mammals of the Southern Ocean have evolved diverse life history patterns and foraging strategies to accommodate extreme fluctuations in the physical and biological environment. In light of ongoing climate change and the dramatic shifts i
Collaborative Research: Weddell Seals as Autonomous Sensors of the Winter Oceanography of the Ross Sea
The proposed project will investigate the coldest and driest parts of the Transantarctic Mountains (Ong Valley at Nimrod Glacier and Moraine Canyon at Amundsen Glacier) where the lack of running water and biological activity in the modern envir
Collaborative Research: Systematic Analysis of Landscape Evolution and Surface Ages in Transantarctic Mountains
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 11-5).  The LISSARD project (Lake and Ice Stream Subglacial Access Research Drilling) is one of three research components of the WISSARD integrative initi
Collaborative Research:  Integrative Studey of marine Ice Sheet Stability and Subglacial Life Habitaats in Western Antarctica - Lake & Ice Stream Subglacial Access Research Drilling (LISSARD)
This award supports a project to develop a robust analytical technique for measuring the stable isotopes of CO2 in air trapped in polar ice, and to reconstruct the isotopic signature 13C of CO2 over the last glacial to interglacial transition (
Developing a glacial-interglacial record of delta-13C of atmospheric CO2
Ecology, Evolution, Systematics & Population Biology
This project will deploy a new Fabry-Perot interferometer (FPI) at the U.S. Palmer Station located in the Antarctic Peninsula. The FPI will observe mesospheric and thermospheric neutral winds and temperatures using multiple nightglow emissions
Collaborative Research: Thermospheric Neutral Wind Observation from the Antarctic Peninsula
We will continue in situ balloonborne ozonesonde measurements through 2010. These ozone measurements, begun in 1986, documented the decline and minimum in ozone observed as chlorine increased and reached its maximum. The recent measurements sho
Measurements of Antarctic Ozone and PSC Profiles in a Time of Decreasing Chlorine, Climate Change and Fluctuations in Polar Vortex Strength.
The purchase of a high power, femtosecond laser system is proposed.  This laser system will generate 2 millijoule, <150 femtosecond pulses at 800 nm with a repetition rate of 1 kHz.  These pulses will be used to pump an optical parametric ampli
Purchase of an Ultrafast Laser System for Materials Chemistry
With support from the Chemistry Research Instrumentation and Facilities: Multiuser program (CRIF:MU), the Departments of Chemistry at the University of Southern California (USC) and California State University - Fullerton (CSUF) will collaborat
Collaborative Research Acquisition of a 400 MHz at the University of Southern California
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).With support from the Chemistry Research Instrumentation and Facilities: Multiuser program (CRIF:MU), the Department of Chemistry at the University
Upgrading the NMR Facilities with Enabled Cyberinfrastructure
Intellectual Merit: The MARGINS program ends in 2009, and the organization, synthesis, and integration of the most important results is a high priority for each of the four experiments. This proposal outlines a 3-year collaborative effort (betw
MARGINS: Collaborative Research: Synthesis and Integration of Magmagenetic Controls for Subduction Factory Focus Sites
Fund are provided for conducting high-pressure experiments to investigate the fate of sediments as they are progressively subducted to greater depths. In particular, two major questions are addressed that are relevant to the chief goals of the
MARGINS: Collaborative Research: Melting of Carbonate-bearing Sediments in Subduction Zones
Habitat degradation and loss may represent the most critical threats to biological diversity.  While ecological effects of human activities at the ecosystem and community levels have received considerable scientific interest, evolutionary impac
Collaborative Research: Human-induced Phenotypic Variation in an Endemic Livebearing Fish
BROWN UNIVERSITY IN PROVIDENCE IN STATE OF RI AND PROVIDENCE PLANTATIONS
'This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).' Terrestrial plants display remarkable variation in many aspects of leaf form. Leaves serve as main sites for photosynthesis, and are thus primar
Collaborative Research: The Evolution of Leaf Form in Viburnum (Adoxaceae)
The goal of this research is to improve understanding of severe convective storms using numerical models with particular attention to genesis, structure and evolution of supercells and tornadoes in increasingly realistic environmental condition
Collaborative Research: Investigating Supercell/Tornado Genesis, Structure and Evolution Using Observations and Numerical Models
The goal of this project, 'A Computational Investigation Into Biological Motion Perception,' is to develop a computational theory of biological motion perception by integrating modeling with psychophysical experiments.  The theory addresses the
CAREER: A COMPUTATIONAL INVESTIGATION INTO BIOLOGICAL MOTION PERCEPTION
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).    The project addresses fundamental questions in the realm of symplectic topology (the mathematical structure behind classical mechanics) and its
CAREER: The Symplectic Categrory, Floer Field Theory, and Relations to Gauge Theory and Topology
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).    Quantum computing is a scientific field that combines some of the deepest intellectual concerns of computer science and physics. Ultimately, we
CAREER: Efficient Computation in the Physical World
This project will develop the ideas behind, and tools required for, a Rationale Management System that captures design decisions made during software development.  The approach utilizes technology developed to support the Semantic Web, using S
CAREER: Rationale Capture for High-Assurance Systems
Migration is a fundamental characteristic of the life history of many organisms allowing individuals to take advantage of different habitats as environments change seasonally.  For example, over two-thirds of all landbirds that breed in tempera
Connectivity and the En Route Biology of Migratory Birds
This award will improve our understanding of biomembranes reinforced by embedded skeletons using two representative examples: insect wing and fish fin. The focus will be the correlation between the bio-architecture and locomotion performance a
CAREER: Performance of Skeleton-Reinforced Biomembranes in Locomotion
This CAREER award supports an integrated research and education program emphasizing the theoretical study of feedback control and entanglement production with continuous quantum measurement in solid state systems. A theory will be developed tha
CAREER: THEORY OF FEEDBACK AND ENTANGLEMENT WITH CONTINUOUS QUANTUM MEASUREMENT IN THE SOLID STATE
The process of sentence comprehension involves incrementally accessing the meaning of individual words and combining them into larger representations. In this process, readers / listeners use probabilistic cues to guide their expectations of up
COLLABORATIVE RESEARCH: BAYESIAN CUE INTEGRATION IN PROBABILITY-SENSITIVE LANGUAGE PROCESSING
The research objective of this Faculty Early Career Development (CAREER) project is to advance the capabilities of micro-transfer printing through a fundamental investigation of the process mechanics that combines experimental characterization
ARRA CAREER: A Fundamental Investigation of the Mechanics of Micro-Transfer Printing Processes for Manufacturing Multifunctional Microsystems
Some of the major challenges that the world faces today are how to feed the ever-increasing population and to find the ways to deal with global climatic change. A better understanding of molecular mechanisms involved in plant growth and develop
ARRA-CAREER: Characteristics of two new Arabidopsis mutants with altered response to auxin - IOS-0845305
This is a CAREER award to support the research of Dr. Hongfang Liu in the Department of Biostatistics, Bioinformatics and Biomathematics at Georgetown University. Dr. Liu is a second-year, tenure-track Assistant Professor. Natural language proc
Natural Language Processing for Biological Knowledge Management
Research Institutes & Public Policy Analysis
While the nervous system operates with information, the mechanics of the body and the environment in which it is embedded constitute a world of forces. Work on the mechanics of the body and on the nervous system is rarely undertaken in a joint
CAREER: Infomechanics - The Interdependence of Animal Information Acquisition and Mechanics
CAREER: Integrated Modeling for Watershed Management The principal objective of this proposal is to advance integrated modeling as an approach for building next generation watershed models to support environmental management. Integrated modelin
CAREER: Integrated Modeling for Watershed Management
Quantifying the global fossil fuel carbon dioxide (CO2) flux at high space/time resolution has emerged as a critical need in both carbon cycle and climate change science. The Vulcan Project led by the Principal Investigator (PI) has recently co
Career: Highly Resolved, Process Driven Fossil Fuel Carbon Dioxide Inventory to Advance Carbon Science, Climate Science and 21st Century Decision Making Public Engagement
This CAREER proposal describes a research program that will explore the opportunities for new discoveries at the Large Hadron Collider( LHC) at CERN using the Compact Muon Solenoid (CMS) detector. With pp collisions at 14 TeV, the LHC is expect
CAREER: RESEARCH IN PARTICLE PHYSICS WITH CMS
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).The research objective of this award is to understand deformation science in ultralight, single-crystal, hexagonal close-packed magnesium-lithium (
CAREER: Fundamental Insights into Deformation of Lightweight Alloys from Discovery-Class Atomistic Simulations
The PI proposes to develop tools to enable the introduction of exogenous DNA into specifically targeted cells in the brain of a live rodent, opening the door to cell-targeted genetic manipulation. This new capability will extend the power of ge
CAREER: OPTICS IN BIOLOGICAL RESEARCH, EDUCATION, AND OUTREACH
In this CAREER proposal the PI, proposes to study the target-site search strategy of DNA-binding proteins. The PI will develop a reaction-diffusion methodology to model the facilitated diffusion of a protein finding its target site. The reactio
CAREER: Target-Site Search of DNA-Binding Proteins
One of the most important issues in the geosciences is the growing disparity between the workforce needs and our ability to produce well trained students. This project is examining whether inquiry-based approaches to education and research can
CAREER: Implementing Inquiry-Based Approaches in Geoscience Education and Research
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).Dr, Miguel Morales (University of Washington) will work towards removing the astrophysical and instrumental foregrounds from HI (neutral hydrogen)
OHIO STATE UNIVERSITY RESEARCH FOUNDATION
Since its founding in 1891, the Ohio State University Herbarium has grown to become the premier collection of plants from Ohio,  documenting the change in plant diversity and distribution in the state through the last century. This project focu
(ARRA) Databasing of the Ohio flora at The Ohio State University
The Towson University Biodiversity Center (TUBC) was created in 2007 to consolidate existing collections as a single management unit. The two largest, most extensive, and oldest collections are the botanical and entomological collections. These
Improvements to the Botanical and Entomological Collections at the Towson Unviersity Biodiversity Center
The aim of this project is to contribute to future advances in mass spectrometry by studying ionic processes outside the mass spectrometer.  Progress is reported on six interrelated studies that involve ion chemistry at atmospheric pressure.  (
Ion Reaction, Ion Dissociation and Ion Collection in the Open Laboratory Environment
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). The Organic and Macromolecular Chemistry Program in the Chemistry Division at the National Science Foundation supports Professor Rajendra Rathore
Design and synthesis of new (electro-active) ladder and helical polyphenylene motifs for molecular wires
Amines are volatile organic compounds (VOCs) emitted to the atmosphere from a number of sources including animal feeding operations. (AFOs) Significant literature evidence indicates that amines in the atmosphere act as precursors for fine parti
REACTIONS AND FATE OF AMINES IN THE ATMOSPHERE EMITTED FROM ANIMAL FEEDING OPERATIONS
Coral reef ecosystems are highly endangered by recent increases in temperature and by projected increases in ocean acidification. Although temperature has been identified as a driver of some coral disease outbreaks, nothing is known about direc
COLLABORATIVE RESEARCH: Influence of Temperature and Acidification on the Dynamics of Coral Co-Infection and Resistance
Media priming has been established as one of the most important ways in which the information environment of electoral campaigns affects public opinion. By changing the criteria citizens use to evaluate policies and politicians, the media condi
Collaborative Research: The Measurement and Identification of Media Priming Effects in Political Science
Purdue University is awarded a grant to implement a complete informatics system for identifying conserved RNA structure topologies, and for finding new examples of similar topologies in sequence databases. This will allow RNA researchers the sa
The University of Kentucky has received a grant to build cyberinfrastructure to help researchers understand the messenger RNA (mRNA) generated using new high throughput sequencing methods. Next generation deep sequencing technologies applied to
Exon Splice Pattern Characterization of the Whole mRNA Transcriptome
Researchers at Rice University have been awarded a grant for an interdisciplinary project in software development, evolutionary biology and comparative genomics that will create new computational methods and web-based resources for comparing an
Reconstructing 700 Million Years of the Evolution of Genome Organization: Tools and Community Resources
VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY
This multidisciplinary project focuses on how an introduced disease, white pine blister rust, can alter ecosystem function through the mortality of whitebark pine, a keystone and foundation species of subalpine and treeline communities of the w
Implications of an Invasive Forest Pathogen for Alpine Treeline Dynamics
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). Intellectual Merit. Surface waves are believed to play a key role in the upper ocean boundary layer, yet do not appear explicitly in any of the ma
Cyberinfrastructure (CI) that supports the global research community by linking together researchers, computational resources, instruments, and data, has had a significant impact on the science and engineering research communities. At the heart
CI-Logon: Secure Access to National-Scale CyberInfrastructure
This proposal is aimed at exploring the development of a highly scalable software framework for global algorithms in three dimensions, such as Fast Fourier Transforms(3D FFT) and other analogous algorithms, tuned for massively parallel petascal
EAGER P3DFFT+: A Highly Scalable Framework for Fourier-like Transforms in Three Dimensions
Head Start ARRA Expansion: This award is for expansion of Head Start services for one classroom of 17 children in Howard County.  Per a community assessment, it was determined that Howard County was underserved.  This award authorizes hiring of
SOUTH CENTRAL MISSOURI COMMUNITY ACTION AGENCY
Head Start ARRA Expansion:  This award provides for ARRA Head Start Expansion funding to serve 20 preschool age children  in a center base option. The HS program promotes school readiness by enhancing the social and cognitive development of chi
I-80 W. of Rye Patch Intg. To E. of Humboldt Intg
Highway Infrastructure Investment - Interstate resurfacing - From funding for use in any Area (flexible)
Interstate 80, Wood River to Grand Island
This project by Anna Berge at the University of Alaska is to continue the research that was encompassed in her earlier project on the Aleut language that was funded as an NSF CAREER award. The goals of the original CAREER project were to docume
Continuing Support for Aleut Linguistics and Language Learning Materials
I-82/Valley Mall Blvd - Rebuild Interchange
INSTITUTE OF GLOBAL ENVIRONMENT AND SOCIETY, INC.
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).                                                                                              The proposed work by the Center for Ocean-Land-Atmosp
Collaborative Research: Predictability of the Physical Climate System
This project will focus on further development of a model of upper atmospheric phenomena known as Blue Jets, Blue Starters, and Gigantic Blue Jets. Blue Jets are narrow cones of blue light that propagate upward from the top of a thundercloud an
The FIREBIRD mission(Focused Investigations of Relativistic Electron Burst Intensity, Range and Dynamics)is a targeted, goal-directed, space weather CubeSat mission to resolve the spatial scale size and energy dependence of electron microbursts
CubeSat:Firebird: Focused Investigations of Relativistic Electron Burst Intensity Range and Dynamics
Research and Development in the Physical, Engineering, and Life Sciences (except Biotechnology)
UNIVERSITY CORPORATION FOR ATMOSPHERIC RESEARCH
Researchers at NCAR aim to address Antarctic climate variability on interannual, multidecadal and longer timescales over the past ~250 years as a means to better understand the underlying physical mechanisms controlling climate change in the so
Applying Ice Cores, Instrumental Climate Records and Climate Modeling Towards a Mechanistic Understanding of Antarctic Climate Variability on Interannual to Multidecadal Time Scale
Georgia Tech investigators will provide an improved data synthesis in the area of air-sea interaction, combining available satellite data, historic and recent field observations and improved turbulent flux models for the high wind conditions th
ARRA: A HIGH-RESOLUTION ANALYSIS OF OCEAN SURFACE TURBULENT FLUXES FOR THE SOUTHERN OCEAN
Two models have been proposed to describe controls over microbial biogeography. One model proposes that microbes are ubiquitously distributed across the global environment, and that environmental conditions select for taxa physiologically adapt
Collaborative Research: The Role of Snow Patches on the Spatial Distribution of Soil Microbial Communities and Biogeochemical Cycling in the Antarctic Dry Valleys
This effort seeks to develop a better understanding of how the nonlinearly coupled thermosphere and ionosphere are driven asymmetrically in polar storm events, and how coupling between these domains affects overall system-level response. Goals
Collaborative Research: Understanding the Asymmetric Thermospheric Response to Polar Driving
A postulated key factor in controlling the future fate of the West Antarctic Ice Sheet, for instance in the area of the Amundsen Sea embayment, is the extent to which warm Circumpolar Deep Water (CDW) intrusions may flow up onto the continental
COLLABORATIVE RESEARCH: ATMOSPHERE-ICE-OCEAN INTERACTIONS IN THE EASTERN ROSS SEA
This award supports a project to measure the concentration of the cosmogenic radionuclide, Beryllium-10 in the deep WAIS divide ice core. Since cosmogenic radionuclides are one of the key parameters used for absolute dating of the ice core and
Collaborative Research: Cosmogenic Radionuclides in the Deep WAIS Divide Core
The paucity of conventional meteorological observations over the Antarctic continent represents a major challenge to both weather forecasts and climate analysis. This puts a premium on the productive use of satellite data, including non-traditi
Collaborative Research: Atmospheric Data Assimilation Techniques for Antarctic Applications
Antarctic Aeronomy & Astophys PENGUin VI Space Physics Research Based In Antarctica
Collaborative Research: PENGUin - A High-Latitude Window to Geospace Dynamics
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  With this award from the Chemistry Research Instrumentation and Facilities Multiuser Program (CRIF:MU), Professor John E. Straub and colleague Se
Acquisition of an EPR spectrometer for cyber-enabled research and education
The Analytical and Surface Chemistry Program of the Division of Chemistry will support the CAREER development of Prof. Matthias Batzill of the University of South Florida. Prof. Batzill and his research group will investigate the surface and in
CAREER: Nanoscale surface properties of functional metal oxides
This proposal seeks $500K (1/2 total cost) in funding to acquire a new electron microprobe. NASA will fund the other 50% in a separate funding action. The current Cameca SX50 probe is 18 years old, heavily used (400 hours / month), and has supp
Acquisition of a New Electron Microprobe for The University of Arizona
Food webs describe the flow of resources through ecosystems from producers (plants) to primary consumers (herbivores) and on to secondary consumers (predators). Food webs are especially complex in diverse tropical rainforests where numerous spe
Beta diversity of plant-insect food webs along an altitudinal gradient in the tropics
This project will increase our understanding of how lakes shift from nutrient-poor to nutrient-rich states and the potential impact of a cyanobacterial species in that process and, in general, in nutrient cycling in nutrient-poor lakes.  We are
COLLABORATIVE RESEARCH: Opening Pandora's Box with a Biotic Key: Can Cyanobacterial Blooms in Nutrient-Poor Lakes Accelerate Eutrophication?
One of the most critical threats to biological diversity is the habitat fragmentation and degradation caused by human activities. Significant advances in our understanding of the ecological effects of human activities have been made in recent y
Methanobactin (Mb) is a small copper-chelating molecule isolated from methanotrophic bacteria, organisms that utilize methane as their sole carbon source. Methanobactin facilitates copper uptake and may also function in regulation of methane mo
Acquisition and Internalization of Copper by Methanotrophs
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).While much has been learned about hurricane structure and intensity change from observational analyses and mesoscale model simulations, much less i
Ensemble-based hurricane state estimation, intensity prediction, and targeting
Research project. At the heart of each eukaryotic cell is the nucleus, a complex structure highly organized into many distinct functional domains to perform two fundamental roles: the maintenance of the genome and the distribution of the geneti
Co-Transcriptional Recruitment and Activity of the Spliceosomal snRNPs
The intellectual merit of this project is to understand cellular asymmetry and membrane adhesion, two processes that are not well understood and which are crucial for eukaryotic cells. Many structures, including the mitotic spindle, nuclear por
Eyespot Placement and Assembly in Chlamydomonas
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  The recent completion of the sequences of the human genome, and many others, has provided the raw data on which to build a deep understanding of
Measurement of the Deuterium Kinetic Isotope Effect on Hydroxyl Radical Cleavage of RNA
'This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).'    Microbial structures in Neoproterozoic cap carbonates    Tanja Bosak  MIT, EAR-0843358    ABSTRACT  Life on our planet endured extreme glacia
Microbial Structures in Neoproterozoic Cap Carbonates
With this award Northwestern University will establish an International Materials Institute (IMI) for Solar Energy Conversion. Although conventional silicon and other semiconductor solar cells have achieved high efficiency for solar energy conv
International Materials Institute for Solar Energy Conversion
The atmosphere of the Earth is dominated by two gases, N2 and O2. N2 is virtually inert and has been the most abundant gas since the atmosphere formed. In contrast, O2, which came to comprise 10 to 30% of the volume of the atmosphere over the p
Evolution of the Nitrogen Cycle and the Rise of Oxygen
A common assumption underlying ecological and hydrological views of small stream systems is that beaver damming causes long-term filling of valleys with sediment, creating broad, flat ?beaver meadows?.  Thus beaver activity is thought to promot
Geomorphic influence of beaver on fluvial systems in the greater Yellowstone ecosystem
Intellectual Merit Circadian rhythms are mechanisms that measure time on a scale of about 24 h and adjust physiological processes to external environmental signals. Core circadian clock genes are defined as genes whose protein products are nece
CAREER: Circadian Control of Cell Division and Homeostasis
With this CAREER award from the Organic and Macromolecular Chemistry Program in the Chemistry Division at the National Science Foundation, Professor Scott A. Snyder of the Department of Chemistry at Columbia University will develop new approach
CAREER: The chemistry and biology of halogenated natural products
Many image processing applications rely on a transform or an operator to eliminate the redundancies in images, thus sparsifying the data. The need for multi-resolution makes it difficult for wavelet-like transforms to sparsify local discontinui
CAREER: EFFICIENT IMAGE SPARSIFYING OPERATORS: THEORY, ALGORITHMS AND APPLICATIONS
CAREER: A Computational Approach to Study Molecular Mimicry in Host-Pathogen Interactions
Current concepts of ecosystem ecology center on the coupling between nitrogen availability and biotic demand in controlling retention of nitrogen by ecosystems. Increased nitrogen loss is expected from ecosystems when the nutritional demands of
CAREER: MECHANISMS OF FOREST NITROGEN RETENTION OVER SEASONS, SITES, AND SUCCESSION
Understanding the genetic basis of adaptation is a central goal of evolutionary biology. An exciting advance of the last decade has been the development of studies characterizing the molecular basis of adaptive polymorphism. This CAREER project
CAREER -- CLOVER CYANOGENESIS: INTEGRATING ECOLOGICAL AND MOLECULAR GENETICS IN THE STUDY OF ADAPTATION
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). The research objective of this Faculty Early Career Development (CAREER) project is to establish a rigorous theoretical and experimental foundatio
CAREER: Nonlinear Control for Single Molecule Tracking
Population genetics provides powerful, well-tested theory for the fate of existing versions of genes in a population during evolution. In contrast, no strong quantitative framework exists to predict how new versions of genes arise and take over
CAREER: Distribution of Fitness Effects, Identity and Interaction of Beneficial Mutations Available for Adaptation
Research in phonology has constructed rich mathematical theories to precisely characterize the systematic patterns of sounds observed in human languages. However, such theories have largely ignored how humans process sounds in real time. For ex
CAREER: Integrating Grammatical and Psycholinguistic Approaches to Phonological Processes in Speech Production
Rivers are the dynamic link between terrestrial and aquatic ecosystems. The biogeochemical processes that produce, consume, and transform organic carbon in rivers are critical to understanding regional carbon budgets, the controls on river wate
CAREER: Transformation and Transport of Organic Carbon in the Colorado River-Reservoir System
The proposed microfluidics system uniquely allows examination of a combinations of factors in a physiologically relevant 3D environment, and holds great promise for elucidating guidance principles that underlay neurodevelopment and for identify
CAREER: Engineered Biomaterial Gradients for Control of Neural Cells
This CAREER award applies ecological engineering to the management of environmental systems. It involves application and extension of the Willamette Collaborative Model, being developed and used by federal agencies for water resources planning
CAREER: Ecological Engineering and the Sustainability of Dams: Evaluating Ecohydraulic Outcomes of Climate Change and Mitigation Opportunities in a Regulated River
Intellectual Merit: One goal of tissue engineering is to direct the differentiation, integration, and organization of living cells to produce biological substitutes for organs to meet the need of nearly 100,000 Americans who are waiting for org
Career: Advancing Model Predictive Control of Cell Differentiation
'This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).'  This Faculty Early Career Development project aims to advance nanophotonics by developing a new class of light emitting devices exploiting aper
CAREER: Combined Light and Carrier Localization in High-refractive Index Silicon Nanocrystal Structures: a Novel Approach for Si-based Lasers
Investigation of current and future urban-climate interactions in metropolitan regions of the southwest U.S. .
CAREER INVESTIGATION OF REGIONAL LAND-ATMOSPHERE INTERACTIONS IN SEMI-ARID CITIES USING THE WRF-NOAH-URBAN CANOPY MODEL
The objective of this research is to create a unified theoretic framework for optimal control and estimation of nonlinear dynamic systems. The approach is to (1) establish a rigorous theory and efficient algorithms for solving nonlinear optimal
CAREER:  Unified Optimal Control and Estimation of Nonlinear Dynamic Systems with Closed-Form Solut
TRUSTEES OF THE COLORADO SCHOOL OF MINES
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).    Intellectual Merit: This CAREER proposal integrates research and educational activities in the thematic area of gas-surface dynamics critical t
CAREER: Molecular Perspectives of Gas-Surface Reactions during Growth of Thin Film Nanostructures
BOARD OF REGENTS NEVADA SYSTEM OF HIGHER EDUCATION
The motivation of this research is to understand the complex and dynamic interactions among population growth, water-energy nexus, climate change, and vulnerability, in a coupled human-environmental system. The main objective is the development
Career:  Vulnerability of Water Infrastructure to Climate Variablity and Change:  Implications for Sustainable Water Management
This CAREER proposal focuses on developing an integrated research and education program in biofuels which will aid in enhancing the conversion efficiency of biomass to ethanol, promoting the commercialization of cellulose ethanol, and training
ARRA CAREER: Fundamental Understanding of Behaviors and Impacts of Cell Wall Lignin during Bioconversion of Lignocellulose to Fuel Ethanol
The objective of this integrated research and educational program is to understand the mechanisms that form proteins in living tissues. This understanding is critical for inducing tissue growth for wound healing or disease recovery, and for oth
CAREER: Three-dimensional Optical Image Guided Spectroscopy for Biological Material Analysis
Under this CAREER award the PI will develop and test general theories of cytoskeletal organization, and thereby obtain an understanding of the architecture and dynamics of the metaphase spindle. The project will use fluorescence and polarized l
CAREER: Physical Aspects of Spindle Self-Organization
This CAREER award supports fundamental theoretical condensed matter physics research and education aiming to extend our understanding of superconductivity a state of matter where electrons pair together and act in concert as reflected by an abs
CAREER: Fluctuation Phenomena Near Quantum Phase Transitions
The use of the basic principle of conservation has led to accurate and reliable mathematical models of the physical world. Such models, known as conservation laws, together with the related models such as Hamilton-Jacobi equations, display rich
CAREER: Development and Applications of Discontinuous Galerkin Methods
INTELLECTUAL MERIT: The extracellular matrix (ECM) in human tissues plays a critical role in protecting and nourishing cells by providing cell adhesion sites and sequestering growth factors. Artificially constructed ECM-simulating biomaterials
CAREER: Integrating Biomaterials and Biology for Control of Cell Function in 3D Matrices
This CAREER award supports an experimental research program to develop new techniques for high-precision measurements on cold trapped molecular ions. Sympathetic cooling of charged molecules to sub-Kelvin temperatures has recently been demonstr
CAREER: Precision Spectroscopy of milliKelvin Trapped Molecular Ions
The mycological herbarium at North Carolina State University has the largest and most comprehensive collection of wood decay fungi from the southeastern US. The collection consists primarily of wood decay and plant pathogenic fungi from ecologi
Research and Educational Use of the North Carolina State University Mycological Herbarium Through Improved Computerization and Internet Presence
Pathogens and hosts are engaged in an endless and deadly warfare. Type III secretion system (T3SS) and secreted effectors (T3SEs) are essential virulence factors of gram negative bacterial pathogens, some of which are responsible for the most d
Molecular Basis Underlying Type III Effector Evolution: Discovering the Recognition Specificity of the Diversified HopZ1 Alleles in Pseudomonas Syring
This project will develop methods to site-isolate commercially available Pd, Mn, Cr, and Co catalysts using polymeric thimbles. The structures of the catalysts will not be altered; the method of site-isolation will be compatible with catalysts
Site-Isolation of Catalysts within Smart Thimbles for Cascade Reactions and Recycling
The Analytical and Surface Chemistry (ASC) program of the Division of Chemistry supports the research program of Prof. James V. Coe of  the Ohio State University. The Coe Group has developed a new method for recording 'scatter-free' infrared (I
(ARRA) Microparticles trapped in holes of plasmonic mesh:  Cataloging IR absorption spectra of individual 1-5 micron particles
This project seeks to develop a novel living and stereoselective anionic polymerization using novel dinuclear ambiphilic silicon catalysts. Building off the recently developed anionic polymerization catalyzed by silylium ions, this project will
Living and Stereoselective Aninoic Polymerization by Dinculear Bifunctional Silicon Centers
Plants are sessile, which makes them vulnerable to constant assaults by hostile abiotic and biotic stresses. To ensure normal growth, plants have evolved unique mechanisms to defend themselves against harm from these stresses. The detailed mech
Essential Roles of Receptor-Like Kinases in Brassinosteroid and Cell-Death Control Signaling Pathways
'The Geometrical and Kinematic Evolution of Interplanetary Coronal Mass Ejections'  This team plans to investigate the evolution of interplanetary coronal mass ejections (CME) at large distances from the Sun. With this knowledge, the principal
The Virginia Bioinformatics Institute at Virginia Tech is awarded a grant to develop GenoCAD, a web-based computer assisted design environment for synthetic biology. This infrastructure helps molecular biologists design custom DNA molecules by
GenoCAD: A Computer Assisted Design Environment for Synthetic Biology
This project aims to construct the first marine community phylogeny. It is inspired by the integrative perspective that lies at the core of the modern concept of biodiversity. Empirical realization of this integration requires that study system
Community Phylogeny and Global Phylogeography of the Neuston
The proposed PRE-Depression Investigation of Cloud-systems in the Tropics (PREDICT) is a focused observational field campaign to investigate both the structure and evolution of tropospheric wave-like disturbances in the tropics and sub-tropics
ARRA Characterizing Atlantic Tropical Cyclone Genesis Using Special PREDICT Measurements and Satellite Observations/Products
The North Pacific Subtropical Gyre (NPSG) is the largest ocean ecosystem on Earth, playing a prominent role in global carbon cycling and forming an important reservoir of marine biodiversity. Nitrogen (N2) fixing bacteria (termed diazotrophs) p
Collaborative Research: Oceanic diazotroph community structure and activities in a high carbon dioxide world
Understanding the behavior of 230Th is critical to interpret the sedimentary record and understand how climate change affects oceanographic processes. This study will address the controversy in using this technique based on assumptions made in
230TH DYNAMICS IN THE EASTERN EQUATORIAL PACIFIC OCEAN:TESTING THE 230TH NORMALIZATION METHOD TO ESTIMATE SEDIMENT FLUXES
Although natural radioisotopes, such as Th(IV), Pa(IV, V), Po(IV, II, -II), and Be(II), are important proxies that have long been used in oceanographic investigations, the molecular interactions and binding relationships between radionuclides a
Collaborative Research: Examining the Binding of Radionuclides with Marine Biopolymers, A Comparative Study on TH, PA, BE, PO and PB Isotopes
Geodesy plays an important role in gaining understanding of the tectonics that shape Earth's crust. Subaerial geodesy is a mature, advanced science. Submarine geodesy, on the other hand, limited by the opacity of seawater to electromagnetic rad
Construction and Deployment of a Seafloor Drift-Corrected Pressure Gauge for DeformationObservation at Axial Volcano
Research Experience for Undergraduates (REU) for interdisciplinary program in high performance cumputing.
REU Site:  Iterdisciplinary Program in High Performance Computing
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). The award supports the University of Minnesota REU / RET physics site which introduces undergraduates to forefront research in physics by having t
REU/RET Site: Physics and Astronomy at the University of Minnesota
'This REU Site hosts ten students each year to engage in software language engineering research for eight weeks in the summer. This builds research and technical communication skills in the students through training and practice during the summ
The University of New Mexico / Configurable Space Microsystems Innovation and Applications Center (COSMIAC) is designing a highly- affordable research satellite concept to characterize Ionospheric properties that affect electromagnetic wave pro
REU Site: Spade and Tropospheric Weather Processing Using DotSat
I-85 FROM PLEASANT HILL RD TO OLD PEACHTREE RD-ATMS COMM/SURVE
People are often surprised to learn that their eyes never stop moving, even when they fixate their gaze. Even more surprising: if their eyes did stop moving, they would become blind to stationary objects due to a brain process called ?neural ad
Modulation of Microsaccades and Correlated Neural Responses as a Function of Viewing Task
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).    The proposed research seeks to develop terahertz quantum-cascade lasers (THz QCLs) that operate at high temperatures. Specifically, by end of t
High Temperature Terahertz Quantum Cascade Lasers
Intellectual merit Although several research groups have demonstrated the capability to produce small quantities of functional platelets from megakaryocytic cells (Mks) in culture, producing the 3-6 x 10-11 platelets required for a single trans
Towards Large-Scale Platelet Production from Adult Hematopoietic Stem and Progenitor Cells
The overall goal of this project is to elucidate and quantify the dynamics of the fusion machine of the HIV-host cell virological synapse.   Based on the dynamics, methods will be engineered to alter time-dependent molecular processes controll
GOALI: A Quantum Mechanics Based Method for Properties Predictions and Product Improvements Using Molecular Design
One of the critical challenges of modern reproductive biology is to develop viable clinical approaches to treat infertility.  Embryo implantation represents a crucial step of the reproductive process and its success relies on the culmination of
Modeling L-selectin mediated attachment strength during embryo implantation
The objectives of this research are to gain both a fundamental understanding of the microbial ecology of denitrifying biofilters and to create improved techniques to characterize the reliability of, and also the design of, this and other engine
Identifying Design Principles for Engineered Ecosystems: Denitrifying Biofilters for Sustainable Agriculture
The grant supports nine students a year from Montana to conduct research in China with a Chinese collaborator.
IRES: U.S. China Collaboration on Dinosaur Eggs and Education
The Tolowa Dee-ni' language, a member of the Pacific Coast Group of the Athabaskan language family, is spoken today in and around Smith River, California. It is on the verge of extinction, with only three speakers remaining, two of whom are qui
The Tolowa (TOL) Athabaskan Lexicon and Text Collection Project: Recording the Last Speakers of the Tolowa Dee-ni' Language
Arts, Culture & Humanities, General/Other
Recent reports of environmental and health toxicity of nanomaterials are contradictory due to the wide variation in properties of any given type of nanomaterial.  Thus, it is difficult to classify the toxicity of nanomaterials according to the
Development of a Screening Tool for Nantoxicology
to provide a comprehensive laboratory experience for civil engineering students. The project will add sensing, monitoring, and data transmission capability to the bridge for use by academic institutions and develop internet portals to the lear
Collaborative Research: The Learning Bridge
, a program which brings science to girls in 6th through 8th grade with the purpose of encouraging them to pursue science in their education and careers.
ESTABLISHING SM PROCESSES AND SEEKING BEYOND-SM SIGNALS WITH ATLAS, AND ADDRESSING GAP IN PHYSICS INTEREST OF YOUTH IN CHICAGO
Stochastics and Dynamics: Asymptotics Problems - Mathematical models taking both deterministic and stochastic factors into account are becoming increasingly important in science and technology. These models, as a rule, are rather complicated. O
FRG: Research Collaborative Stochastics and Dynamics: Asymptotic Problems
This FRG builds on various recent successes in mirror symmetry and tropical geometry. On one hand, the Strominger-Yau-Zaslow conjecture has led to work by Kontsevich, Soibelman, Gross, Siebert, Zharkov and others to view mirror symmetry in term
FRG: Collaborative Research: Mirror Symmetry & Tropical Geometry
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). It will provide funds to pursue the analysis of IceCube data. IceCube is a high-energy neutrino telescope currently under construction at the Sout
ARRA: HIGH ENERGY NEUTRINO ASTROPHYSICS WITH ICECUBE AT GEORGIA TECH
This is a travel grant to communicate with colleagues outside US on the search for the sources of the ultrahigh energy cosmic rays
Cosmological Evolution and Very High Energy Astrophysics
The 1930's saw a revolution in astronomy with the first radio astronomical observatories, shattering the serene view of the Universe, revealing violent phenomena and exotic astrophysical objects. Today we stand on the verge of a new revolution
Radio telescopes and gravitational wave observatories: Two windows on the same Universe Dr. Creighton
This program will study the formation and applications of ultracold molecules with translational temperatures less than 0.001 K. The formation of the homonuclear molecule Rb_2 and the heteronuclear molecule KRb will be investigated by photoasso
Formation and Applications of Ultracold Molecules
Dept. of Physics  University of Connecticut
ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640 (A)(5)of the Head Start Act for the Head Start Program Staff.  Head Start promotes the school readiness of low-income children
COLA/QUALITY IMPROVEMENT FUNDING FOR HEAD START PROGRAM TO INCLUDE SALARY AND FRINGE INCREASES, TEACHER/STAFF TRAINING, BUILDING REPAIRS, PLAYGROUND ENHANCEMENTS, AND BUS IMPROVEMENTS.
The award provides for Quality Improvement Funding consistent with the provisions of Section 640(e)(5) of the Head Start Act. The funding provides monies to enhance compensation for educational and family services staff in order to be competiti
CHILD CARE ASSOCIATION OF BREVARD COUNTY, INC.
ARRA cost of living adjustment (COLA) consistent with provisions of section 640 (a) (5) of the Head Start Act.  Funds were also awarded for purchase of canopies for Head Start and Early Head Start playgrounds.
CAPITAL AREA COMMUNITY ACTION AGENCY, INC.
Head Start Program.This award included an ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of the Section 640(a)(5) of the Head Start Act. Our Head Start program has a funded enrollment of 37
Head Start 2009 ARRA/COLA/Quality Improvement Funding
This Award provides for ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Program.  Head Start promotes the school readiness of low-income children throu
Head Start 2009 ARRA COLA Quaility Improvement were awarded to OCAB Community Action Agency, Inc. Head Start Program to serves economically disadvantaged preschoolers, in center-based programs in Orangeburg, Calhoun, Allendale and Bamberg Count
ARRA funds are being utilized to support two major program priorities - staff training and facilites/equipment upgrades.  Funds will be used to support training opportunities by providing supplies, equipment for training and to facilitate webin
Head Start 2009 ARRA / COLA / Quality Improvement Funding
This award provides for ARRA Cost of Living Adjustment (COLA) and Quality Improvement Funding consistent with the provisions of Section 640 (a)(5) of the Head Start Act for the Head Start and/or Early Head Start program. All staff received a CO
Head Start 2009 ARRA Cola and Quality Improvement Funding
Program serves 136 Head  Start eligible children in the Chapel Hill Carrboro school disrict.  Grant funds to be use for: ARRA cost of Living Adjustment to meet increased costs of benefits; Quality Improvement funding to improve staff qualificat
ARRA COLA and Quality Improvement Funding Increase: The Clarke County School District Early Head Start (EHS) and Head Start (HS) program in Athens, GA serves 164 children birth through age four and expectant women (32 center based EHS children
EARLY HEAD START & HEAD START ARRA COLA-QUALITY IMPROVEMENT
ARRA cost of living and quality improvement funding for Dunbar Early Head Start program providing child care for low income families for children from birth to age 3.
This proposed expansion has four main objectives. 1.  Deliver comprehensive child development and support services (including educational, health, mental health, nutritional, and social services) to economically disadvantaged children and their
The Headstart Expansion Award is providing 1 additional classroom at York County, South Carolina to serve 38, 3 and 4 year olds. These funds are startup and prorated operation for the period of September 30, 2009 through September 29, 2010. Wil
Head Start Expansion Grant (04CH3181)was awarded to provide services to seventeen (17) three year old children in one of the poorest inner city areas of Sumter County, South Carolina where high drug trafficking and a magnitude of street level c
The Head Start Expansion Grant will provide quality comprehensive services for 150 three and four year old children in head start centers and partnering sites. These sites are located in Desoto, Clay, Grenada, Oktibbeha, and Panola Counties. Th
ARRA Head Start Expansion. This grant serves 20 children, and pays the salary of one teacher and one teacher assistant. Currently, children from all funding sources are blended into nine classrooms. The grant will continue to pay the salaries o
1st Avenue South, Phase 2A, Multi-modal Enhancements (SW 192 to SW 200)
The purpose of this work is to implement the remedial action (RA) at the South Minneapolis Residential Soil Contamination Site in accordance with the objectives of the remedial design (RD).
The purpose of this work is to implement the remedial action (RA) at Continental Steel Superfund Site in accordance with the objectives of the remedial design (RD).
Technical Assistance involved with identifying the viability of alternative substrates, WholeTree of Clean Chip Residual for use by several rural nursery and greenhouse growers in the state of Alabama.  WholeTree is an alternative substrate con
Technical assistance for development of sustainable alternative substrates for nursery crop growers
I-20/59 Hawkins Crossing Rd. and 23rd Ave. East between SR 19 and US 80
The overall purpose of our Quality Improvement dollars received through ARRA was the expansion of  bilingual services to Hispanic English Language Learners (ELL).  Through the use of culturally and linguistically appropriate instructional servi
'Head Start and Early Head Start COLA and Quality Improvement                                                                                                                                         Ensure that compensation is adequate to attrac
Head Start Cost of Living Allowances & Program Quality Improvements
COMMUNITY ACTION PARTNERSHIP OF RAMSEY AND WASHINGTON COUNTIES
This award provides for ARRA Cost of Living Adjustment (COLA) and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start program.  Head Start promotes school readiness of low-inc
Head Start and Early Head Start COLA increase of 1.84% for the period July 1, 2009 thru June 30, 2010. Head Start and Early Head Start quality improvement funds to upgrade quality of programming.
Head Start: full year part day handicapped training and technical assistance
Head Start/Early Head Start Child Development Program.  The funds will be used for training of staff; hiring of a bilingual family services worker and COLA increases to Head Start/Early Head Start staff.
The Award was to provide the FY 2010 Cost-of-Living Adjustments to Head Start Staff; to offset increased operating costs in other areas of the Stark County Community Action Agency Head Start budget, including increased costs in utilities, facil
COMMUNITY ACTION PARTNERSHIP OF LAKE COUNTY
Lake County Head Start will provide a comprehensive program for 698 children including 10-15% of children with disabilities in accordance with the performance standard guidelines.  The award includes a temporary 1.84% COLA adjustment  for a 12
Head Start Quality Improvement and COLA Purpose is to expand services in the areas of children's literacy and mental health as well as provide a COLA to teaching staff
Head Start Quality Improvement and COLA ARRA
SOUTHEASTERN INDIANA ECONOMIC OPPORTUNITY CORP
This award provides ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start and/or Early Head Start program.  Head Start promotes the sc
COMMUNITY ACTION AGENCY OF COLUMBIANA COUNTY INC
LAKES & PINES COMMUNITY ACTION COUNCIL, INC.
Head Start Full Year Part Day Handicapped Training and Technical Assistance - improve staff compensation to retain quality staff, improve staff qualifications, support staff training necessary to address the challenges of families and children,
Head Start promotes school readiness of low-income pre-school age children through services which includes comprehensive health, developmental and family support. This award provides for ARRA Cost of Living Adjustment (COLA), and Quality Improv
ARRA funding for Head Start staff COLA and education; furnishings.  Head Start Full year Part day handicapped; T & TA
Head Start Full Year Part  Day Handicapped T&TA
COLA increase for HS employees. Quality improvement for HS.
SOUTHWESTERN MINNESOTA OPPORTUNITY COUNCIL, INC.
ARRA Cost of Living Adjustment (COLA) and Quality Improvement consistent with Section 640 (a)(5) of the Head Start Act for Head Start. Head Start promotes the school readiness of low-income children through the provision of comprehensive, healt
OHIO HEARTLAND COMMUNITY ACTION COMMISSION
AARA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act
HEAD START - FULL YEAR PART DAY HANDICAPPED TRAINING AND TECHNICAL ASSISTANCE-INCLUDES ARRA COST OF LIVING ADJUSTMENT (COLA), AND QUALITY IMPROVEMENT FUNDING CONSISTENT WITH THE PROVISIONS OF SECTION 640(a)(5) OF THE HEAD START ACT FOR THE HEAD
HEAD START - FULL YEAR PART DAY HANDICAPPED TRAINING AND TECHNICAL ASSISTANCE
Head Start: educating 370 pre-schoolers for school readiness and empowering their families in six SE MN counties
COMMUNITY ORGANIZATION OF SOCIAL CONCERN INC, THE
COLA adjustment. Quality Improvement funds will be used to: * purchase (10) classroom computers'softwear; * Purchase (8) bi-lingual learning carpets and other supplies;  * hire 2 Hispanic consultants;  * Teacher Aides, Family Service workers' s
Head Start:  Full-year, Part-day Handicapped Training and Techinical Assistance
We requested ARRA COLA and Quality funds to hire a full time Family Service Worker.  We also requested funding to purchase play equipment for the children.  The Education staff needed ongoing training so we requested funds to hire three trainer
Riverbend Head Start & Family Services received funds from the American Reinvestment and Recovery Act to achieve the legislation?s goals to save and create jobs, and spur economic activity and invest in long term economic growth. By improving p
This award provides a cost-of-living increase of 1.84% to all Early Head Start/Head Start employees.  It provides the means to increase the overall Pay Plan by this percentage.  The award also provides funds for education supplies.  Along with
EHS and Head Start 1.84% Cola increases as well as Quality Improvement funds for both grants.
This award for ARRA Cost of Living Adjustment (COLA) and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start and/or Early Head Start program.  Head Start promotes the school r
MUSKEGON AREA INTERMEDIATE SCHOOL DISTRICT
This award provided for ARRA Cost of Living Adjustment (COLA) and Quality Improvement (QI) funding for Head Start in Muskegon and Oceana Counties, Michigan.  Head Start promotes the school readiness of low-income children through the provision
HEAD START: FULL YEAR PART DAY HANDICAPPED TRAINING AND TECHNICAL ASSISTANCE
QUALITY IMPROVEMENT  GRANT (ARRA)FUNDING TO PROVIDE EDUCATION, PROFESSIONAL DEVELOPMENT AND EQUIPMENT TO ENABLE TEACHERS TO BE HIGHLY SKILLED AND COMPETENT AS THEY MEET HEAD START OBJECTIVES.ALSO, TO PROVIDE HEALTH, MENTAL HEALTH AND DISABILITI
The award provides for Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start and/or Early Head Start program. Head Start promotes the schoo
MID MICHIGAN COMMUNITY ACTION AGENCY, INC.
DHHS ACF Discretionary Grant Award No. 05SE8280/01 Early Head Start awards a COLA increase for Early Head Start staff of 1.84% in the amount of $27,631.  Quality improvement funds of $72,956 will be utilitzed to hire new staff to assist familie
EHS ARRA Quality improvement. This award provides for ARRA cost of living adjustments and quality improvement funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start and/or Early Head Start program.
Offices of Mental Health Practitioners (except Physicians)
Head Start ARRA Expansion - The award provides for GCCARD Head Start to expand by 53 additional at risk, income eligible 3 and 4 year old children. Twenty-six children are from the City of Flint and twenty-seven from the Out-County service area
KOKOMO CENTER TOWNSHIP CONSOLIDATED SCHOOL DISTRICT CORPORATION
Head Start ARRA Expansion-Kokomo Center Schools Head Start Program's purpose for the Expansion award is to provide comprehensive services to an additional 130 students and their families.  In this third year of our program, we are providing pre
ROSS COUNTY COMMUNITY ACTION COMMISSION, INC.
This award provides for ARRA Head Start Expansion funded to serve 20 pre-school children, ages 3-5 in Ross County, Ohio.  Head Start promotes the school readiness of low-income children through the provision of comprehensive health, development
COMMUNITY ACTION AGENCY FOR MC HENRY COUNTY
HEADSTART EARLY CHILDHOOD EDUCATION FOR CHILDREN FROM LOW INCOME FAMILIES, EXPANSION FUNDING FOR OPENING A NEW CLASSROOM TO BRING QUALITY EARLY CHILDHOOD EDUCATION TO 16 MORE CHILDREN. PROGRAM INCLUDES TRACKING CHILD DEVELOPMENT IN LEARNING, SO
ARRA Head Start Expansion  This award provides ARRA Head Start Expansion funding to serve 90 additional children. The Head Start program provides comprehensive services for low-income preschool-age children and their families designed to prepar
This award provides ARRA funding for Head Start Expansion to serve 93 children.  The Head Start program promotes the school readiness of low-income children through the provision of comprehensive health, developmental and  family-centered servi
The project name is an award of Head Start Expansion to Coshocton County Head Start.  The project will serve 18 preschool children in a center base option.  Children for the expansion will be recruited in the current service area for Coshocton
Head Start Quality Improvement and COLA. Temporary 1.84% COLA to all HS and EHS staff. Facility corrections to include paving, stucco, flooring. Temporary hiring of substitute staff to support staff completing education. Bonuses for staff compl
This award provides funds to operate the National Superconducting Cyclotron Laboratory (NSCL) at Michigan State University as a national user facility, to support MSU faculty and staff research in nuclear physics, nuclear chemistry, astro-nucle
Operation of the National Superconducting Cyclotron Laboratory at Michigan State University as a National User Facility & Support for its Research Program
US-60; Miami City Limits to McMillan Wash in GLOBE
SR 25/OCEAN HIGHWAY AT NS RAILROAD 5 MI N OF SAVANNAH
NATIVE AMERICAN COALITION OF TULSA, INC.
This Award provides for the ARRA Cost of Living Adjustment (COLA)and Quality Improvement funding consistent with the provisions in section 640 (a)(5) of the Head Start Act for the Head Start Program. Head Start Promotes the school readiness of
Construction of a new water intake structure, pumping station and related appurtenances to provide safe and reliable water to retain a large employer.
Industrial Park Expansion infrastructure installation of water, sewer, streets, curb, and gutter.
Design/Installation of new fire slarm system and fire sprinkler system.
BOSSIER OFFICE OF COMMUNITY SERVICES, INC
Head Start/Early Head Start. 1.84% COLA increase for Head Start/Early Head Start staff. Quality Improvements will be for computers and playground equipment for the centers.  The remaining Quality Improvement will be incentive pay for the Head S
Head Start/Early Head Start - The purpose of this grant award is to fund Cost of Living Adjustments for personnel , professional development, and quality improvements for program consistent with the provisions of Section 640(a)(5) of the Head S
Head Start/Early Head Start Quality Improvement/COLA
Head Start is a comprehensive child development program that serves children ages 3 to 5 and their families. Comprehensive services include: education, disabilities, mental health, nutrition, health, dental, safety, transportation and community
SULPHUR SPRINGS INDEPENDENT SCHOOL DISTRICT
ARRA funding for Cost-of-Living and benefits increase for all staff; and Quality Improvement funds to enhance program.
SOUTHWEST OKLAHOMA COMMUNITY ACTION GROUP
NORTHWEST KANSAS EDUCATIONAL SERVICE CENTER
ARRA cost of living increase of 1.84% for each staff member.  Quality improvement to cover cost of hiring a bilingual teacher associate, tuition and text books for teachers to obtain bacelor's degree in EC, CDA expenses, tuition and text books
FY2009 ARRA COLA Quality This award provides for ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding
CENTRAL TERRITORIAL OF THE SALVATION ARMY
FY 2009 ARRA COLA/QUALITY IMPROVEMENT  ARRA COLA/Quality Funds were used to give and maintain a COLA of 3.5% to employees of the EHS program.  In addition supplies, training and resources were provided to center based partners.  Translation of
Award Description:   Award title is FY 2009 ARRA COLA/Ql. Award type is service. 1. Project name is ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a) (5) of the Head Start Ac
The award for Head Start ARRA Expansion grant number 07SH6131 has provided funding to serve 16 Head Start eligible children.  The Head Start classroom provides comprehensive center-based services in Storm Lake, Iowa.  The classroom services a s
Youth in Need was awarded 46 additional HS slots on Sept 17, 2009, a sum of $416,137 (year one). The purpose of this award is to increase much needed early childhood services, create jobs and stimulate local economies. Community data indicates
Native American Housing Block Grant, Formula Rehabilitation of existing homes to increase energy efficiency and conservation
Highway Infrastructure Investment - Highway restoration and rehabilitation - From funding for use in any Area (flexible)
I-82/Granger to W Grandview EB - Dowel Bar Retrofit and Concrete Rehab
Kamehameha Highway, Replacement of South Punaluu Stream Bridge
Polar Terrestrial environmnets are often described as deserts, where water availability is a critical factor limiting the distribtuion of terrestrial organisms.  In such environments, tolerance of low moisture conditions is likely as important
Collaborative Proposal: Roles for Dehydration and Photoperiodism in Preparing an Antarctic Insect for the Polar Night
Polar terrestrial environments are often described as deserts, where water availability is a critical factor limiting the distribution of  terrestrial organisms. In such environments, tolerance of low moisture conditions is likely as important
(ARRA) Collaborative Proposal: Roles for dehydration and photoperiodism in preparing an Antarctic insect for the polar night
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). This RTG grant at the University of Washington (UW) supports an array of activities that will enhance the education and training of undergraduate
EMSW21-RTG: Research Training Grant in Inverse Problems and Partial Differential Equations
Although earthquakes are commonly modeled as frictional instabilities on planar fault surfaces, most natural faults have a more complex structure. Most displacement appears to be concentrated in one or more relatively narrow (mm to cm scale) ?c
Micromechanics-based Modeling of Dynamic Earthquake Rupture in a Structurally Complex Fault Zone
During the last quarter of a century many 3-D models of the mantle, or its part, have been derived. However, most of them describe only one parameter (for example, S-velocity) and are based on a data set that is limited to a narrow range of fre
Collaborative Research: Studies of the Structure of the Earth's Interior
Title: Research Training in Algebra and related fields.   This RTG project aims to enhance graduate, post-doctoral, and undergraduate training in Algebra, Number Theory, Algebraic Geometry and Combinatorics at UCLA.
EMSW21-RTG IN ALGEBRA AND RELATED FIELDS AT UCLA:  INNOVATIONS IN A SUCCESSFUL PROGRAM
Collaborative Research:  Studies of Solar Wind - Magnetosphere Interactions using Observations of ULF Waves at Manned Stations as Part of an Extensive Ground Array
Collaborative Research: Studies of Solar Wind -- Magnetosphere Interactions  using Observations of ULF Waves at Manned Stations as Part of an Extensive Ground Array
Langmuir circulation (LC) in the upper ocean mixed layer (UOML) is a feature most familiarly observed as linear stripes or sea surface streaks approximately parallel to the wind direction. These result from helical (ovoid) water cells rotating
Collaborative Research: Impact of Langmuir Circulation on Gas Transfer and Photosynthesis in the Southern Ocean:  A Large Eddy Simulation Study
This award supports a project to develop a precise gas-based chronology for an archive of large-volume samples of the ancient atmosphere, which would enable ultra-trace gas measurements that are currently precluded by sample size limitations of
for Large-Volume Samples of the Past Atmosphere, Taylor Glacier, Antarctica
An interdisciplinary team of researchers will focus on describing the high productivity patchiness observed in phytoplankton blooms in the mid to late summer in the Ross Sea, Antarctica. Key hypotheses to be tested and extended are that intrusi
Collaborate Research:Modified Circumpolar Deep Water Intrusions as an Iron Source to the Summer Ross Sea Ecosystem
Collaborative Research: Synthesis and Integration of Magmagenetic Controls for Subduction Factory focus sites Intellectual Merit: The MARGINS program ends in 2009, and the organization, synthesis, and integration of the most important results i
This proposal describes research efforts in technologically advanced materials at the University of Toledo, which the acquistion of a state-of-the-art scanning electron microscope (SEM) will advance.  The acquistion of a new SEM and suitable ac
Acquisition of a Cyber-Enabled Mulit-User Scanning Electron Microscope
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  With support from the Chemistry Research Instrumentation and Facilities: Multiuser program (CRIF:MU), the Department of Chemistry at the Universi
ARRA Upgrade of Cyber-Enabled Facility for Computational Chemistry Research and Education
The Department of Chemistry at North Carolina State University proposes to acquire a state-of-the-art cyber-enabled Bruker Biospin E-500-EleXsys X/Q-band Electron Paramagnetic Resonance (EPR) spectrometer. This instrument would replace a quarte
CRIF:MU Acquisition of Cyber-Enabled X/Q-Band CW EPR Spectrometer For Use in Research and Education
Central American Magmatic Volatile Histories as Recorded by Apatite Phenocrysts
MARGINS: CENTRAL AMERICAN MAGMATIC VOLATILE HISTORIES AS RECORDED BY APATITLE PHENOCRYSTS
In project GlobalWatershed, graduate Fellows will conduct research in watershed science topics, at a range of scales and cultural contexts, while working with middle/high school teachers to create lesson plans that transfer this knowledge to th
New GK12 GlobalWatershed: Integrating Rural and Global Perspectives with Research and Technological Advances
This project focuses on advancing understanding of critical issues in atmospheric ice nucleation, one of the most basic processes affecting precipitation and impacting the radiative properties of cold clouds. Incomplete understanding of ice ini
Laboratory and Ground-Based Studies Addressing Unresolved Aspects of Atmospheric Ice Nucleation
This project will produce the first user-friendly identification keys and global classification for the leafhopper subfamily Deltocephalinae, a diverse, economically and ecologically important group of plant-feeding insects, comprising 980 gene
REVSYS: Reclassification of the Leafhopper Subfamily Deltocephalinae (Hemiptera: Cicadellidae) with Emphasis on the Polyphylectic Tribe Athysanini
SAN JOSE STATE UNIVERSITY RESEARCH FOUNDATION
The ability to document and understand long-term trends in ocean climate and ecology, including the role of human activities on the biosphere, depends on an adequate knowledge of natural interdecadal fluctuations. The proposed research will doc
LTRB:Collaborative Research: Decadal Variation in Antarctic Marine Benthic Ecosystems
This proposal seeks funding to support developing a high pressure, high temperature calibration scale for diamond anvil cell (DAC) studies. Existing pressure scales are plagued with issues particularly at high temperatures. Developing a pressur
Collaborative Research: High Pressure Calibration at High Temperatures
Photosynthetic systems use reaction center proteins to direct electrons across membranes to convert solar energy into chemical energy. The products of green plant photosynthesis are carbohydrates and oxygen, which form the basis for life on ear
Electrochemical Studies of Redox Cofactors in Photosynthetic Reaction Centers
This project will initiate efforts to identify DNA catalysts (deoxyribozymes, DNA enzymes) for catalysis of reactions of small-molecule substrates with multiple turnovers. Nucleic acids are used as natural catalysts in the form of ribozymes (RN
Development of DNA Catalysts for Synthetic Chemistry
Removal of non-coding segments known as introns from precursor (pre) to messenger (m) RNAs in eukaryotic nuclei via splicing is an essential step in gene expression. The two-ste splicing reaction is carried out by a large complex of protein and
Salicylic acid (SA) is a signaling molecule in the plant immune system.  SA accumulates follow-ing pathogen invasion, triggering activation of the transcription regulator NPR1, which in turn induces resistance to a broad spectrum of pathogens.
Dissection of the salicylic acid-stress signaling pathway in plants
In humans and other animals, acoustic communication often takes place in large social groups or 'networks' comprising multiple signalers and receivers. In such environments, the background noise generated by simultaneously signaling individuals
CAREER: The Receiver Psychology of Acoustic Communication Networks
Cooperating with others often not does not appear advantageous to all involved parties, yet individuals in many species cooperate in sometimes complex ways. Biparental care offers a model system for experimental analysis of simple cooperation.
Behavioral Dynamics of Biparental Negotiation
In this research, the complex role of dynamics in the association of RRM-RNA complexes will be investigated. The RNA recognition motif (RRM) is a ubiquitous RNA binding protein that is found in all organisms and is involved in all steps of gene
Contributions of Dynamic Processes to RNA Protein Complex Formation
It is said that 'seeing is believing', and we take it for granted that vision operates efficiently and accurately. This suggests that vision is easy. However, failed attempts at producing computer vision demonstrate exactly the opposite--vision
Collaborative Research: Modeling Perception and Memory: Studies in Priming
Hiaki (also known as 'Yaqui' and 'Yoeme') is an endangered Uto-Aztecan language spoken in Southern Arizona and in Sonora Mexico. The Arizona dialect of Hiaki is moribund; its 70-80 native speakers are all fifty years of age or older, and it is
Hiaki Grammar: Documentation, Analysis and Teaching
The variability problem has been extensively researched in adults but has received relatively little attention in the population on whom it is likely to exert the greatest influence - infants and young children who are building their first voc
Effects of Variability on Early Word Learning
The ability of coastal wetlands to survive accelerated sea level rise is a critically important and open question. Coastal marshes, which are dominated by the marsh grass Spartina alterniflora, build the land vertically (accrete) through a comb
Collaborative Research: Eco-geomorphic coupling: Vegetation transition and sedimentary responses to faulting
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  Malicious software is one of the most pressing security problems on the Internet. The main reason for the apparent failure of current defense app
CAREER: Toward eliminating malicious code
The nucleosome is the fundamental unit of chromatin, formed of 147 base pairs of DNA wrapped around a histone octamer protein core.  Post-translational modifications in this structured histone core are likely to play vital roles in assembly, ma
(ARRA) CAREER: Chemical tools to probe histone H4 modifications in the nucleosome core
This project is designing new data structures and efficient algorithms for scaling modern machine learning techniques to massive datasets, and their application to recent sky surveys to solve central problems in astronomy. The long term goal is
ARRA: CAREER: SCALABLE MACHINE LEARNING FOR ASTROSTATISTICS
With pervasive usage of embedded systems in our daily life and infrastructures, strengthening the security of embedded system in its design and implementation has become a critical priority for the research community. This project targets augme
CAREER: Architectural Enhancement and Design Methodologies for Secure Processing in Embedded Systems
Cognitive radios and multi-antenna systems are two recent components that each offers a great potential for improving spectrum efficiency. The former enables opportunistic spectrum access (OSA), while the latter enables multiple-input, multiple
CAREER: Optimization and Design of Next-Generation Cognitive Mesh Networks: From Theory to Practice
This CAREER project is formulated to study the multiplexing and networking of passive wireless sensors for engineered sensor skins. The proposed multi-disciplinary research is focused to resolve three major challenges of sensor skins, i.e. elec
CAREER: Passive Wireless Sensor Networks for Bio-inspired Sensor Skins
Just like any other large social group, the honeybee colony critically relies on an efficient transfer of material and information among individuals. The interaction network which makes this possible is, however, also open to exploitation by pa
Career: Organization of Social Structure and its Influence on Transmission Dynamics in a Honeybee Colony
Although spinal cord injury is a relatively rare occurrence (affecting about 11,000 people annually in the US), these debilitating injuries occur most commonly in young people who go on to live for many decades with extreme health complications
CAREER: Adaptive Biomaterials that Enable Cell-Induced Remodeling and Drug Release
As cell biologists, geneticists, or engineers, one routinely over-expresses a gene in a cell, observes the cell, and compares its behavior to the parent. Yet multiple genes, not one, often determine cell phenotypes. One example is the sustained
CAREER: Analyzing and engineering multi-gene cooperation to generate celllines for therapeutic protein production
TECHNICAL SUMMARY: This CAREER proposal supports an integrated research and education program that centers on solving problems involving colloidal particle self-assembly using theoretical and computational methods. Unlike most of the work done
CAREER: Self-Assembly in Two and Three Dimensions: from Crystal to Surface Design and Back
The goal of this project is to develop the first chemo- and regioselective [2+2+2] cyclotrimerization reaction and establish it as an approach for the rapid assembly of natural products and libraries of analogs. These research objectives will b
CAREER: Solid-Supported Cyclotrimerizations - A Library Approach to Research and Teaching
This CAREER award is for research on creating an energy conversion system that converts the now landfilled petrochemical portion (plastics) of municipal solid wastes (MSW) to value added liquid fuel. The research includes carbon dioxide capture
CAREER: Sustainable Energy Conversion of Solid Wastes with Integrated In-Situ Carbon Sequestration
The research objective of this Faculty Early Career Development (CAREER) project is to develop analytic sensitivity methods for numerical simulations of fluid-structure interaction. The sensitivity methods can be employed in the design and asse
Career: Particle Finite Element Reliability Methods for Fluid-Structure Interaction
This CAREER award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). Investments in advanced computational infrastructure ('cyberinfrastructure' (CI)) represent a large and growing percentage of the U.S. scie
CAREER: Governing Collaborative Science: Cyberinfrastructure, Scale, and Governance in the Networked Ecological Sciences
This proposal for career development is motivated by two overarching goals: [A] Investigation of African easterly wave (AEW) origin and storm track dynamics; and [B] Improving the current paradigm for mathematical instruction in undergraduate a
CAREER: Dynamics of African Easterly Waves: Integrating phenomenological studies and Mathematical Instruction in Atmospheric Science
What determines human health is known only in part. Even where causal pathways have been identified, great uncertainty frequently exists regarding the strength of the relationship. Compelling and precise estimates of these relationships are nee
In this project supported by the Experimental Physical Chemistry Program, Professor Aaron Massari of the University of Minnesota will employ two-dimensional infrared vibrational echo spectroscopy (2D-IR VES) to understand how the molecular mot
CAREER: Understanding the Influence of Fast Molecular Motions on Charge Mobilities
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). The research funded by this CAREER award will probe exotic states of matter in artificially engineered materials. In particular, this project will
CAREER: PHOTOEMISSION SPECTROSCOPY OF THIN FILMS: A NEW LABORATORY FOR STUDYING QUANTUM MANY-BODY INTERACTIONS
NATIONAL BUREAU OF ECONOMIC RESEARCH, INC.
Intellectual Merit Anyone interested in studying price movements in any asset market needs first to understand how information moves through agents in the market, and ultimately into prices. A critically important, and yet understudied, mechani
The field of economics known as mechanism design considers how to design incentive schemes that reach desired outcomes. It has many   applications and it represents one of the most important developments in economic theory over the past 30 year
(ARRA) Career: Behavioral Mechanism Design
The Organic and Macromolecular Chemistry Program in the Chemistry Division at the National Science Foundation supports Professor Jerry Yang at the University of California San Diego whose research will evaluate and optimize the hydrolytic prope
CAREER: Development of acid-cleavable linkers for drug delivery
At the forefront of condensed matter physics, the design and development of new materials has been the root of many fundamental discoveries. The ability to predict and synthesize targeted compounds represents one of the main challenges of our u
CAREER: Spin Fluctuation in Itinerant Electron Magnetic Systems
Intensification of hydrologic regimes due to climate change will have important impacts on biogeochemical processes and ecosystem services, but quantifying these impacts experimentally remains a key challenge for earth scientists. My research g
CAREER- Climate Change Impacts on the Interrelationship between Iron Cycling and Organic Carbon:
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  The Organic and Macromolecular Chemistry Program in the Chemistry Division at the National Science Foundation supports Professor Michael F. Mayer
CAREER:  Preparation of Materials Composed of Mechanically Interlocked Nanoscale Species
TECHNICAL SUMMARY This CAREER award is funded by the Division of Materials Research and the Physics Division. It supports theoretical and computational research and education on quantum-many body systems with a focus on ultracold atom systems w
CAREER: Cold atom mixtures of fermions and bosons on a lattice
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). It will fund neutrino studies at MIT as a tool to search for signatures of Beyond the Standard Model Physics. Over the past decade, neutrino studi
Equipment purchase, personnel support, supplies, etc. for improvements to the Arthropod Collection in the Museum of Southwestern Biology
Improvements to the Division of Arthropods Collection, Museum of Southwestern Biology
An award has been made to the herbaria (museum plant collections) of Arizona State University (ASU) and the Desert Botanical Garden (DES), under the direction of Drs. Leslie R. Landrum and Andrew M. Salywon respectively, to expand the Southwest
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). The Inorganic, Bioinorganic, and Organometallic Chemistry Program supports the efforts of Dr. Mekki Bayachou of Cleveland State University to expl
Mechanistic insights into nitric oxide synthase catalytic function
Bayesian methods are being used by a growing number of researchers to infer phylogenies because of the computational efficiency of these methods (Huelsenbeck, et al.2001). However, the stochastic process underlying the implementation of these m
The University of Maryland College Park is awarded a grant to develop new algorithms and a suite of software tools based on a general and flexible definition of a 'network module' in order to extract meaningful biological clusters from noisy an
Better Network Modules: New Tools for Protein Network Analysis
The University of Arizona is awarded a grant to develop and evaluate a set of algorithms/software to help computers to read and ?understand? taxonomic descriptions of plants, animals, and other living or fossil organisms. The major functions of
Fine-Grained Semantic Markup of Descriptive Data for Knowledge Applications in Biodiversity Domains
Purdue University is awarded a grant to develop novel computational algorithms and software for building protein structure models, which can identify and utilize very distantly related template structures for the modeling. Considering the growi
Template-Based Protein Structure Prediction Beyond Sequence Homology
Recent work by this team shows that geothermal springs in major river valleys near the Main Central Thrust zone of the Himalayan front are significant sources of carbon dioxide. To date we have shown that this source of CO2 exceeds the consumpt
Collaborative Research: Quantifying CO2 Fluxes Along the Himalayan Arc
This project develops and analyzes a new model in economic theory. The goal is to model individual preferences in a simple model where information may arrive in two stages. We introduce two general classes of representations, one for individual
Collaborative Research: A Subjective Model of Temporal Preferences
The project will enable ten undergraduate students per year to participate in scientific research for three months per year at the University of Michigan in the Space Physics Research Laboratory through a Research Experiences for Undergraduates
REU Site: Space Physics Research Laboratory, University of Michigan
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  Global change drivers, including warmer temperature, changing precipitation, increasing atmospheric carbon dioxide and ozone, deposition of react
REU Site: Biosphere-Atmosphere Interactions in a Changing Global Environment
Despite pouring millions of dollars into programs to further the democratization of Africa, donors remain uninformed about one of the most important facets of politics on the continent: Why do Africans vote they way they do? Most observers of A
The Research Experience for Undergraduates (REU) Site at Georgia Institute of Technology will continue to offer summer research opportunities for undergraduate students recruited nationwide and teachers from inner-city and suburban public high
ARRA: REU + RET SITE: STRUCTURE PROPERTY CORRELATIONS ACROSS LENGTH SCALES
REU SITE:  Sustainable Energy in Chemical Engineering PROJECT SUMMARY:   1. Intellectual Merit Funding is requested in this proposal for renewed support of our existing REU site in the Department of Chemical Engineering at the University of Sou
REU SITE:  Sustainable Energy in Chemical Engineering
With the support of the National Science Foundation, an interdisiplinary team at the University of Arizona will greatly expand work in progress on characterizing (1) sources of turquoise in the southwestern USA and northern Mexico; (2) sources
Developing Heavy Stable Isotopes for Provenance of Turquoise, Metals and Glass
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).    The transport of tracers in baroclinic flows will be investigated, using the perspective of the modified Lagrangian mean approach of Nakamura.
The world today functions in an age of international migration and financial globalization, not only in terms of the century-old phenomenon of people and money crossing national borders, but also in the unprecedented scope and complexity that t
Financial Institution and Immigrant Integration in the U.S. and Canada
It is widely recognized that bacterial indicators do not co-occur with infectious viruses, nor do they respond in the same manner to environmental or engineered stressors. Thus, a more appropriate indicator for health risks of infectious viruse
ARRA TT Virus: A Potential Indicator of Human Enteric Viruses in Source and Drinking Waters
This is small equipment grant for the acquisition of a high-energy, narrow-linewidth, injection-seeded Nd:YAG laser. This instrument will be the primary component for advanced imaging studies to investigate the gas-phase scalar mixing in turbul
(ARRA) Acquisition of a High-Energy, Narrow Linewidth Laser for Gas-Phase Scalar Mixing Studies in Turbulent Spray Flows
Many liquid/gas two-phase flows involve topology changes, where atomization of the liquid is governed by the dynamics of the phase interface. Although atomization is crucial in many technical applications ranging from energy conversion to pharm
LES Subgrid Modeling of Liquid-Gas Phase Interface Dynamics
Over the past two decades, the fundamental importance of iron and other bioactive trace metals in structuring marine food webs and biogeochemical cycles has been realized. Even more recently, over the past several years, the international ocean
Changing Phytoplankton Trace Metal Rquirements in a High CO2 Ocean
Dependable and effective access to large amounts of sustained computing power is strategic to scientific discovery in a vast range of disciplines. An ever expanding number of science communities worldwide rely on Condor software tools to harnes
ARRA: Flight-Worthy Condor: Enabling Scientific Discovery
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).Subtidal communities in temperate geographic zones of the world are faced with changes caused by fishing, climate change, habitat alteration and in
Effects of Marine Preserves and Nonindigenous Species on Rocky Subtidal Communities: Indirect Interactions, Disturbance and Community Dynamics
This research addresses the lack of chronologic information that exists for Midwestern glacial and postglacial environments. Absolute dates for key geomorphic events are lacking in the geomorphic literature, mainly because of the paucity of woo
Collaborative Research Theoretical And Paleoenvironmental Implications Of Dating And Characterizing Loess Deposits In The Upper Midwest
Intellectual merit: This proposal studies preference for timing of resolution of objective uncertainty in the sense of Kreps and Porteus (1978). It builds on a simple model with two stages of information arrival. Two general classes of represen
COLLABORATIVE RESEARCH: A SUBJECTIVE MODEL OF TEMPORAL
Collaborative Research: Computation-driven small area inference with applications. This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  There is a growing demand to assess various measures of human
Collaborative Research: Computational - Driven Small Area Inference with Applications
UNIVERSITY OF NORTH CAROLINA AT GREENSBORO
Collaborative Research: Radial Growth Responses among Naturally-Occurring Western U.S. Conifers under Changing Environmental Conditions  This project is designed to examine and compare the effects of changing environmental conditions on the rad
Collaborative Research: Radial Growth Responses among Naturally-Occurring Wester
Collaborative Research: Radial Growth Responses among Naturally-Occurring Western U.S. Conifers under Changing Environmental Conditions   Climate and atmospheric composition change research in coniferous ecosystems of the northern Rockies, USA
Collaborative Research: Radial Growth Responses among Naturally-Occurring Western U.S. Conifers under Changing Environmental Conditions
Agriculture, Forestry, Fishing and Hunting
The University of Kansas and the University of Connecticut are awarded collaborative grants to develop software to gather, visualize, and analyze large data sets of the distribution of species on continental and global scales. The proposed comp
Collaborative Research: Extending Lifemapper to Enable Macroecological Research
The proposed work is to examine changes in structural and physical properties along the southern Costa Rica subduction zone using 3D seismic imaging. At this location the plate boundary transitions from stable sliding to unstable sliding. Under
Collaborative Research: A 3D Seismic Investigation of the Transition to seismogenic behavior along the southern Costa Rica subduction zone
The objective of the proposed REU site in the Agricultural and Biological Engineering Department (ABE) at the UF is to provide eight undergraduate students in engineering with eight weeks of research experiences, focused on sustaining water res
Interdisciplinary research in water resources
This three year REU site award will provide an opportunity for undergraduate students to do research focused in the area of bioengineering education. It will build upon the practices established during a successful REU program at the Vanderbilt
REU Site: Bioengineering Education Research
The renewal REU site award will provide research experiences for 10 undergraduate students each year over a three year period. The students will be engaged in state-of-the-art interdisciplinary research projects in the fields of solar cell char
REU Site: Sustainable Energy Alternatives and the Advanced Materials (SEAM)
Project Summary: The University of Houston-Downtown has been recognized as a Hispanic Serving Institution as well as a Minority Serving Institution by the U.S. Department of Education. The objective of the REU (Research Experience for Undergrad
REU (Research Experience for Undergraduates) : Research Experience in Algorithm Design and Analysis for Students in Undergraduate Institutions
'Imaging and Analyses of Heliospheric Structure for SHINE Using IPS and SMEI Remote-sensing observations to study the physics and global properties of heliospheric structure, such as coronal mass ejections (CMEs) are of fundamental importance t
SHINE: Imaging and Analyses of Heliospheric Structures for Using InterPlanetary Scintillation (IPS) and Solar Mass Ejection Imager (SMEI)
This project involves measuring formaldehyde and alpha-dicarbonyl (mainly glyoxal) concentration gradients and fluxes within and above the canopy at Blodgett Forest in the Sierra Nevada of California using state of the art instrumentation as pa
ARRA Analysis of volatile organic compound oxidation chemistry and secondary organic aerosol formation with novel instrumentation for in situ carbonyl detection
Many serious medical conditions, from hemorrhage to coronary artery disease to diabetes, are associated with disruptions in blood flow. It has been observed that dramatic beneficial effects on blood flow arise from addition to blood of low conc
ARRA Blood flow in the microcirculation: model studies of the effects of drag-reducing polymer additives
Leaking underground storage tanks (LUST) sites have resulted in BTEX (benzene, toluene, ethylbenezene and xylenes) compounds, oxygenates such as methyl tert-butyl ether (MTBE) or tert-butyl alcohol (TBA) migrating into surface and groundwater a
Stable Isotope Probing to Assess Bioremediation of LUST Contaminants: Addressing Existing MTBE/BTEX and Probable Future Ethanol/BTEX Contamination
There is a critical shortage of organs, with the organ waiting list currently at 100,000 requests and increasing by 5% every year. This study focuses on the liver: 27,000 die in the US annually due to liver disease, 3,000 while on the organ tra
'The design of clinically effective materials for the surgical repair of ruptured ligaments remains a challenging biomedical engineering problem. Currently, tissue grafts from the patient and cadaveric sources are the only clinically effective
Collaborative Research: Ligament Tissue Engineering
The overall goal of the project is to better understand the mechanisms by which nanomaterials released into the environment may be taken up into fish species and cause toxicity.  It is known that nanomaterials can enter through the gills or the
Nanoparticle Transport to Oocytes and toxicological Consequences
The proposed research will have a significant impact on the state of the art of smart biopolymers for protein purification and their implementation in an industrial setting.
GOALI:Industrial Implementation of Smart Biopolymers for Antibody Purification
Intellectual merit: The intellectual merit of this proposal results from the first demonstration of the directed evolution of specific cell penetrating peptides (SCPPs). The directed evolution technique offers tremendous potential for the engin
Directed Evolution of Specific Cell Penetrating Peptides
This project will research the industrial implementation of smart biopolymers for antibody purification.
Industrial Implementation of Smart Biopolymers for Antibody Purification
Current assessment of microbial pollution in recreational waters involves measurement of fecal indicator bacteria (FIB) as proxies for human pathogens. FIB concentrations display diurnal variability such that the time the sample is collected dr
Collaborative Research: The role of sunlight in controlling fecal indicator bacteria and humanvirus concentrations in recreational waters
Bionanomaterial Uptake and Fate in Corbicula fluminea  Similar to what has been observed with pharmaceuticals and personal care products, consumer use and disposal of 'bionanomaterials' will inevitably result in their discharge to municipal was
Bionanomaterial Uptake and Fate in Corbicula fluminea
Intellectual Merit: Heart valve disease is the third most common form of cardiovascular disease and has shown a steady rise in incidence over the past 20 years. The only option currently available to treat this condition is open-heart surgery.
Cyclic Strain and the Aortic Valve Endothelium
Department of Agricultural and Biological Engineering
0854298Jiang'This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).'Cell membranes and membrane-based organelles actively mediate several intracellular signaling and trafficking decisions. A growing nu
Ultra-low Fouling Peptide-Based Thin Films, Nanoparticles, and Polymers
This award supports a collaborative research program between the University of South Florida and the UNESCO-IHE Institute for Water Education in Delft, the Netherlands. The Institute for Water Education is the largest postgraduate water educati
IRES: Sustainable Clean Water Technologies for the UN's Millennium Development Goals - A Partnership Between UNESCO-IHE (Delft, Netherlands) and Univ. South Florida
The goal of the award is to leverage mobile technologies and sensors to empower individualsand organizations with personal feedback about their energy use and carbon emissions and suggestions on how to improve.  Our work includes transportation
Collaborative Research: Mobilizing Information Technology Systems to Motivate Reduced Energy Consumption and Carbon Dioxide Emissions
Intellectual merit: This project will advance the fields of bone biomineralization and tissue engineering while promoting teaching, training and learning. A peptide that can specifically not only bind to but also nucleate hydroxylapatite (HAP)
Biomineralization and self-assembly of genetically modifiable nanofibers to build bone tissue engineering scaffolds
Advanced oxidation processes (AOPs) have shown promise to destroy many of the emerging organic contaminants in water, and are being considered in potable water treatment, wastewater treatment, site remediation, and industrial applications. AOPs
ARRA: RATE CONSTANTS AND TOXICITY ESTIMATION FOR THE COMPUTER DISCOVERY OF BYPRODUCTS FATE IN ADVANCED OXIDATION SYSTEMS
In this project we propose the study of SiC membranes which show the potential to overcome some of the difficulties other membranes face, which have proven unstable in the presence of O2 and steam at temperatures higher than 300C; these are the
Fundamental Studies of Novel SiC Nanoporous Materials for Separation Applications
The project will quantify stratosphere-troposphere exchange (STE) using novel transport diagnostics: one-way cross-tropopause flux distributions and path densities with their associated transport rates. This new approach will extend the current
Flux Distributions and Path Densities: A New Look at Stratosphere-Troposphere Exchange (STE)
The research objective of this award is to develop fundamental understanding of the effect of probe-sample thin-fluid-film forces on the accuracy of dynamic atomic force microscopy (AFM) images acquired in ambient air. In particular, the work w
Influence of thin-fluid-film effects on surface characterization with dynamic atomic force microscopy
Research will be carried out into the semiclassical behavior of spin systems, using spin-coherent-state path integrals and other mathematical and theoretical physics tools. A significant part of this research will be done in the context of unde
Collaborative Research: Semiclassical Methods for the Study of Spin Systems
The PIs will study some fundamental problems in algebraic number theory, particularly problems related to the deep links between Galois representations and special values of L-functions (as conjectured in the Birch-Swinnerton-Dyer Conjecture an
FRG: Collaborative Research: Automorphic forms, Galois representations, periods and p-adic L-Functions
Proteomics has contributed to advances in understanding fundamental biological phenomena and the detection and curing of diseases. Protein microarrays enable large amounts of data and quantitative studies for proteomics. However, these are not
Label-Free Protein Arrays Based on Linear Dendron Macromolecular Layers and In-Situ Real Time EC-SPR-AFM Methods
The objective of this collaborative research is to transform two major operating bridges with their approach highways and the associated diverse human and natural systems, into a living laboratory. This laboratory will be leveraged to explore
Collaborative Research:  The Learning Bridge
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).    Atomic clocks are the most accurate devices ever made by mankind, and have many important technological applications. The best atomic clocks ar
Atomic Ensembles Entangled by Light for Measurements Below the Standard Quantum Limit
Storage system researchers have typically used I/O traces from various sources to drive their analysis and research. However, these I/O traces fail to adequately capture the effect of I/O on application performance. Moreover, they do not scale
CI-ADDO-NEW:  Storage System Trace Collection
TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
This is the report from the last quarter update      The project effort to date is precisely aligned with the project award description.    Our target date for public access to the database is January 2012.  Specific activities to date include:
II-EN: SYNCHRONOUS MULTI-SENSOR HUMAN MOTION ACQUISITION FACILITY
All the necessary research infrastructure has been built. In this quarter, we have started using it to perform a variety of research activities. Few examples include motion planning for the Barrett WAM performing manipulation, incorporating aco
The physics program supported by this grant is directed at the study of spin and flavor structure of nucleons. Research will be carried out at the DESY laboratory in Germany as part of the HERMES collaboration, and at the Fermi National Laborat
It will fund the Syracuse University group to participate in the Cryogenic Dark Matter Search (CDMS) experiment and research to develop and test detectors for possible future Dark Matter detection experiments. Observations indicate that 80% of
The proposed research is addressing the important question of the impact of human intervention on uncertainties that drive a particular system. Methods will be developed to assess whether interactions between decisions and uncertainties exist.
Collaborative research: Decision-dependent stochastic processes - inference and optimization
Coalescing compact binaries, binary star systems with black holes or neutron stars in highly relativistic orbits, are the most important potential sources of gravitational radiation for current laser interferometer detectors such as LIGO. The t
Dynamical Formation and Evolution of Compact Binaries
This proposal details a plan to study collisions between polarized electrons and chiral molecules, as well as simple diatomic molecules. The proposed experiments address physics questions about the dynamics of electron–molecule scattering, pa
This award provides support to Washington University in St. Louis in their effort to build an extremely sensitive and versatile torsion balance.  The instrument will probe possible deviations from the inverse square law of Newtonian gravity at
EXPERIMENTAL INVESTIGATION OF FORCES IN THE SUBMILLIMETER RANGE
'A New Method For Producing Ultra-Cold Molecular Ions' This award is for support of a project working to demonstrate a novel method for producing and trapping ultracold molecular ions. The impact of this method for producing ground-state, ultra
A NEW METHOD FOR PRODUCING ULTRA-COLD MOLECULAR IONS
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).Ice-based buoys exist that can measure temperature profiles, but these are not optimized for observing the open sea. Thus the objective of this pro
UpTempO: Measuring the Upper Temperature of the Arctic Ocean
This award will support the continuation of UVR (ultra-violet radiation) measurements at the Ultraviolet Spectral Irradiance Monitoring Network (UVSIMN) sites at Barrow, Alaska, and Summit, Greenland. UVR has been measured at Barrow since 1990
The International Tundra Experiment (ITEX) Arctic Observing Network (AON) collects data on phenology, plant growth, community composition and ecosystem properties as part of a greater effort to study environmental change in the Arctic.  The net
Arctic Observing Networks: Collaborative Research: Sustaining and amplifying the ITEX AON through automation and increased interdisciplinarity of observations.
This award supports the continuation and expansion of long-term measurements of the Arctic atmosphere, snow, and other Earth system components at the Summit, Greenland, Environmental Observatory (GEOSummit). The original measurement program beg
Continued Core Atmospheric and Snow Measurements at the Summit, Greenland Environmental Observatory
The 2007 Anaktuvuk River (AR) fire created a unique opportunity to observe the response of a pristine tundra landscape to a major disturbance. The area burned is large enough (>1000 km2) that its impacts can be measured directly at multiple sca
Fire In the Arctic Landscape: Impacts, Interactions And Links To Global and Regional Environmental Change
SR-86; Kinney Rd to La Cholla Blvd in TUCSON
Description The purpose of this award is to expand the existing 9th Street corridor in east Little Rock from its current terminus at Bond Street to the Dassault Falcon Jet facility on the side of the Little Rock National Airport to better provi
ARRA - Economic Adjustment Assistance, Ninth Street Extension
The US Geological Survey Advanced National Seismic System (ANSS) National Operations Center (NOC) in Golden, Colorado has commenced the development of improved seismic monitoring and information delivery systems in response to the December, 200
Instruments and Related Products Manufacturing for Measuring, Displaying, and Controlling Industrial Process Variables
Fort Independence Stimulus Rehab Project
Head Start/Early Head Start COLA and Quality Improvement to serve low-income children and families in Southwest Colorado. Head Start for low-income children and families provides comprehensive services(health, nutrition, cognitive & language de
Head Start 2009 ARRA Quality Improvement and COLA (ARRA)
0-5 Head Start 2009 ARRA COLA Quality Improvement Funding
Head Start/Early Head Start Quality Improvement and COLA 08SE0046 141275.00 6/30/2009 to 9/30/2010.  This award support services to 216 HS children and 50 EHS enrollees.  The Head Start program promotes the school readiness of low-income childr
The award provides for ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the Provisions of Section 640(a)(5)of the Head Start Act for the Head Start program.  Head Start promotes the school readiness of low-
WYOMING CHILD AND FAMILY DEVELOPMENT, INC.
ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of 640(a)(5) of the Head Start Act
Head Start/Early Head Start 2009 ARRA COLA/Quality Improvement Funding
ARRA cost of Living Adjustment, and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act.
$21,193 Cost of living adjustment (COLA) increase of 1.84% for 36 Head Start staff salaries over 12 month period following 7/1/09, and $63,492 Quality Improvement funds over period of 7/1/09-9/30/2010, $31,012 of which is to be used toward the
Head Start ARRA COLA & Quality Improvement ? Head Start is a comprehensive child development program that serves children from birth to age 5, pregnant women, and their families. It is a child-focused program that is aimed at increasing the sch
Clayton Educare Early Head Start received a FY2009 Funding Guidance award in the amount of $86,987 to be used in accordance with program Instruction ACYF PI-HS-09-06 as follows:  Clayton Educare Early Head Start has used $27,541 in ARRA funding
CATHOLIC CHARITIES AND COMMUNITY SERVICES OF THE ARCHDIOCESE OF DENVER, INC.
Head Start 2009 ARRA COLA Quality Impovement Funding
ARRA Head Start Expansion Grant This award provides for ARRA Head Start Expansion funded to serve 51 children. The Head Start program provides services for low-income families with young children (ages 3 to 5) to promote the school readiness th
COPPER RIVER BASIN REGIONAL HOUSING AUTHORITY
Native American Housing Block Grant (Forumla) Recovery Act Funded
Native American Housing Block Grants (Formula) Recovery Act Funded
TLINGIT HAIDA REGIONAL HOUSING AUTHORITY,
Native American Housing Block Grant, Formula-New Construction, acquisition, rehabilitation including energy efficiency and conservation and infrastructure development
1. Infrastructure (extend water/sewer/eletricity) to 12 mobile homes in Moenkopi Village - 12 FEMA trailers.   2. Rehabilate six (6) rental units - Winslow.   3. Infrastructure for HTHA office trailer.  4. Provide septic systems for 3 mutual he
SALT RIVER PIMA-MARICOPA INDIAN COMMUNITY SOCIAL SERVICE, THE
NAHBG,formula-new construction and rehab that includes the following: Painting of 111 homes. Electrical upgrades to 83 homes. Insulation upgrades to 88 homes. Roof overlays to 60 homes and 4 roof repairs. stucco repair to 23 homes. Door and har
New Single-Family Housing Construction (except Operative Builders)
Construct a five bedroom foster care home; construct a four bedroom home; replace roofs on up to six LR units; rehab two homeownership units
Lessors of Residential Buildings and Dwellings
Modernization of 1937 Housing Act Rental Unit; Make Improvements to community park in 1937 Housing Act Rental unit; and Planning & Administration
Native American housing Block Grant (Formula) Recovery Act Funded
Installed energy efficient HVAC sytems in 63 apartments and replaced single pane metal clad windows in 101 units with energy effiecient double pane vinyl clad windows.
2008 La Jolla ARRA Formula (New Construction)
La Jolla 2008 ARRA Formula - New Construction
2008 Pauma ARRA Formula - (Paving Site Work)
2008 SANTA ROSA ARRA - FORMULA (NEW CONSTRUCTION)
Native American Housing Block Grant Formula - Home Acquisition and Energy Conservation & Efficiency training, rehab, planning & administration, crime prevention and safety and purchase of energy audit/wx equipment.
Crime Prevention & safety, Renewable Energy & Wx Training - Purchase audit /weatherization equipment - Rehab and weatherization of Tribal homes - Home owners purchase assistance -Planning and admin staff
American Indian and Alaska Native Tribal Governments
This Grant will be used to help rebab 22 houses on the reservation.
FALLON PAIUTE SHOSHONE INDIAN HOUSING AUTHORITY
Provide cost efficient and alternative heating sources for homes including hot water and heaters, weatherization or roofing.
Native American Housing Block Grant, Formula - New construction, acquisition, rehabilitation including energy efficiency and conservation, and infrastructure development.
LAGUNA HOUSING DEVELOPMENT & MANAGEMENT ENTERPRISE
NAHBG Forumula El Rito & New Construction
American Recovery and Reinvestmetn Act.  Fiscal Year 2008 Indian Housing Plan Amendment.  Indian Housing Block Grant Number: 08SH3506730.
A sensor for monitoring of the curvature of the surface of an optic such as a mirror or beam-splitter will be developed using heterodyne measurements of the phase of a laser beam reflecting off the surface of the optic. The objective is to prov
RUI: Modeling and Monitoring of Thermal Effects in Advanced LIGO
Computational creativity has been a goal of artificial intelligence since nearly its inception. But while many interesting models have been developed, and some of these have even produced interesting creative works, most have been built on foun
Major: Computational Creativity: Building a Model of Machine Generated Humor
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). The project objective is to develop proton conducting ceramic membranes with enhanced transport properties for use in hydrogen membrane fuel cells
SURFACE CRYSTALLIZATION TO OPTIMIZE NANOSTRUCTURE OF PROTON CONDUCTORS IN HYDROGEN MEMBRANE FUEL CELLS
The primary objectives of this collaborative research study are to 1) better understand the interactive roles played by lane-changing and car-following, 2) quantify their effects on oscillations, and 3) develop a mathematical simulation model t
ARRA: COLLABORATIVE RES: ANALYSIS AND MODELING OF TRAFFIC INSTABILITIES IN CONGESTED TRAFFIC
Cosmic-ray Physics with IceCube IceCube is a neutrino observatory at the South Pole, which consists of 5160 sensitive optical detectors in the deep ice as well as 324 of the same detectors in tanks on the surface.  The deep detectors look for u
Building information models (BIMs), which represent the three dimensional (3D) geometry and high-level semantics of a facility, are increasingly used in the Architecture, Engineering, Construction, and Facility Management (AEC/FM) industry. Mos
Automating the Creation of As-built Building Information Models
Nearly hundred years after the debut of Einstein's theory of general relativity, gravitational waves are viewed as one of the most intriguing but still elusive astrophysical phenomena. They are expected to be emitted by extreme astrophysical so
SR-86 Across Brawley Wash w/o TUCSON (MP 145.69 to MP 148.3)
The project is the upgrade of the existing water treatment plant in St. James Parish East Bank Water Treatment Plant in Convent, Louisiana.  The project will increase the treatment capacity of the water plant from 1.5 million gallons per day to
East Bank Convent Water Treatment Expansion
The project work is in the Central Region Geologic Hazards Team, Geologic Division, which is headquartered in Golden, Colorado.  The Geologic Hazards Team (GHT) conducts research in geology, geophiysics, seismology, engineering seismology, geom
Project Description: - Hire two full-time employees (Dual Language Learner (DLL) & Bilingual Floater (BF)) - Provide professional development to teaching staff to improve staff qualifications (through use of DLL) - Purchase classroom supplies f
We have been granted a cost-of-living adjustment.  There will be an increase of 1.84%, in the amount of $11848 for headstart.  This amount will be obligated to pay for staff salaries over the 12 month period following the effective date of this
Saguache County Community Council - Center Headstart
Head Start Quality Improvement and COLA (ARRA)  This award will be used for a staff salaries and fringe benefits for the COLA portion of the grant.  The renovation portion of the grant will be used to renovate the North Valley Head Start facili
Data Processing, Hosting, and Related Services
Name of project:  Head Start 2009 COLA and Quality Improvement Funding Number of children to be served:  The Sioux Falls Head Start program serves 414 children.  All 414 children will be touched by this project in one or more ways. 2.  Program
Head Start 2009 COLA and Quality Improvement Funding
Provide a one year 2.25% ARRA Cost of Living Increase for all Head Start staff.  Provide stipends to teachers who complete an AA or BA degree prior to September 2010, for teachers who successfully complete one or more class leading to a degree,
Laramie County Head Start provides services to 60 Early Head Start families pregnant to the age of 3 years old; 250 children ages 3-5 years old in a center-base option; and 10 children ages 3-5 years old in a home-base option. We serve the area
ARRA money was requested to give 22 Head Start employees in Brush a cost of living increase. The cost of living increase was important to give to staff to be able to retain quality teachers and staff. ARRA money was also requested to increase t
This award provides for an ARRA Cost of Living Adjustment (COLA) consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start program.  Head Start promotes the school readiness of low-income children through the
Thsi award provided for ARRA cost of living and quality improvement funding consistent with the provisions of section 640 (a)(5) of the Headstart Act for the Headstart and/or early Headstart program.
Headstart 2009 ARRA COLA Quality Improvement funding
Funding Agency Code Awarding Agency Code Award Date  7590 7590 06-30-2009  Amount of Award Sub Account Number for Program Source (TAS)    $ 61,502 Not Collected by HHS  Program Source (TAS)* CFDA Number   751537 93.708  Total Number of Sub Awar
Native American Housing Block Grant, Formula - New construction and rehabilitation including energy efficency and conservation.
Aleutian Housing New Construction and Rehabilitation
Native American Housing Block Grant, Formula--New construction, acquisition, rehabilitation including energy efficiency and conservation, and infrastructure development.
Native American Housing Block Grant (Formula) - The ARRA funds are for the construction of two four-plexes. It will result in eight (8) new rental units.
Native American Housing Block Grant (Formula)
The Recovery Act Funds will be used to modernize current assisted stock. Twenty per cent (20%) will be used toward administration.
Barona Band of Mission Indians Housing Department
ENTERPRISE RANCHERIA INDIAN HOUSING AUTHORITY
American Recovery and Reinvestment Act (Recovery Act) of 2009 - Native American Housing Block Grant - Indian Housing Amendment
NORTH FORK RANCHERIA INDIAN HOUSING AUTHORITY
Construct 2 rental homes survey 25 homes, rehabe/weathere homes, hire 5 employees
Acquisition of Rental Housing, Rehabilitation of Rental Housing, Planning and Administration (101h)
The ARRA funds are for capital improvements. Phase 1 covers fifty-one (51) dwelling structures. The Phase 1 work includes: site preparation, roof installation and weatherization. Phase 2 covers ninety-nine (99) dwellings and the work includes:
The ARRA funds are for capital improvements. Phase 1 covers sixty-nine (69) dwelling structures. The Phase 1 work includes: site preparation, roof installation and weatherization. Phase 2 covers ninety-nine (99) dwellings and the work includes:
LITTLE RIVER BAND OF OTTAWA INDIANS, INC.
Native American Housing Block Grant, Formula - New Construction
SAULT SAINTE MARIE TRIBE OF CHIPPEWA INDIANS
The award dollars will be used for modernization and rehabilitation of low income rental units which will enhance the energy effiecency therby reducing the over-all utility costs for the tenants.
Native American Housing Block Grant, Formala - New construction, rehabilitation including energy efficiency and conservation.
Develop and Improve Low Income Housing on the Red Lake Reservation
Native American Housing Block Grant Formula - rehabilitaion of Low Rent units
Objective 1, 2 and 3 -Extensive renovation and exterior painting and patching of 223 rental units that are still in the Blackfeet Housing FCAS.  These activities support modernization of 1937 Housing Act.  The outcome is to improve energy effic
Program Activity: The ARRA funds will provide the painting of thirty-nine (39) exterior siding and trim on low-income rental housing units which will require the following tasks: Power Washing of exterior siding and trim, sanding and priming of
Native American Housing Block Grant, Formula- Rehabilitation and energy conservation on Current Assisted Stock units and Homeownership homes.
Homeownership and Current Assisted Stock Rehablitation and Home Improvement  project
Native American Housing Block Grant Formula
Grant Writer Project Duplex Construction Day Care Project
Rental and Homebuyer Housing Modernization and Rehabilitation Project
SOUTHERN PUGET SOUND INTER-TRIBAL HOUSING AUTHORITY
Shoalwater Bay Indian Tribe housing project, water and sewer line installation
Shoalwater Homes I Water & Sewer Line Installation
COMPLETE REHABILITATION OF RENTAL HOUSING UNITS.  24 UNITS HAVE BEEN IDENTIFIED.
Native American Housing Block Grants (Formula) Recovery Act Funded.
The Recovery Act funds was provided as a supplemental to the existing 2008 Indian Housing Block Grant (IHBG) allocation and is a one-time funding.
Native American Housing Block Grant, Formula-new construction, acquisition, rehabilitation including energy efficiency and conservation, and infrastructure development
Native American Housing Block Grant, Formula - New Construction, acquisition, rehabilitation, including energy efficiency and conservation, and infrastructure development.
ALEUT COMMUNITY OF ST PAUL ISLAND TRIBAL GOVERNMENT
Native American Housing Block Grant, Formula - New construction, acquisition, rehabilitation including energy efficiency and conservation, and infrastructure development
Rehabilitation of 5 Housing Units Through Replacement of Siding
Native American Housing Block Grant, Formula-New construction, acquisition, rehabilitation including efficiency and conservation, and infrastructure development
IHBG funds provided under ARRA to rehabilitate (5) substandard homes; focus on providing energy efficiency and conservation to enhance a better livelihood for five families.
ARRA funds for the purpose of construction, acquisition, rehabilitation, or infrastructure development.
Purchase and construction of new low income rental homes for Tribal members.
Rehabilitation of Affordable Housing on the Manzanita Indian Reservation.
RINCON BAND OF LUISENO MISSION INDIANS OF THE RINCON RESERVATION CALIFORNIA
ROOM ADDITIONS TO EASE OVERCROWED CONDITIONS
American Recovery and Reinvestment Act of 2009 Indian Housing Block Grant
American Recovery and Reinvestment Act of 2009
amended the NAHBG plan to use the funds for acquiring multifamily housing.
Smith River Rancheria has requested to amend its NAHBG plan to use the funds for acquiring multifamily housing.
Rehabilitation of elderly low-rent units and the Housing Department entry way.  Along with Planning and Administration Costs.
Prairie Band Potawatomi Nation Housing Department-rehabilitation of elderly low-rent units and remodel of Housing Department entry to make handicap accessible
Indian Housing Block Grant provided under the Recovery Act
Renovation of 20 Affordable Housing Rental Units and Temporary housing of tenants during renovation
Indian Community Development Block Grant - Preserve and create jobs, promote economic recovery, assist those impacted by the recession, and invest in transportation, environment and infrastructure that will provide long-term economic benefits.
Native American Housing Block Grant, Formula- New construction, acquisition, rehabilitation including energy efficiency and conservatio, and infrastracture and development
Native American Housing Block Grant, Formula-new construction, acquisition,rehabilitation including energy efficiency and conservation ans infrastructure development.
Native American Housing Block Grant, Formula - New Construction, acquisition, rehabilitation including energy efficiency and conservation, and infrastructure development.
CONFEDERATED TRIBES OF COOS, LOWER UMPQUA AND SIUSLAW INDIAN
Formula Allocation to implement Native American Housing and Self determination Act (NAHASDA) Activities including affordable housing construction, affordable housing remodel.
Native American Housing Block Grant, Formula - new construction acquisition, rehabilitation including energy efficiency and conservation and infrastructure development.
2008 Recovery Act Manufactured Rental Housing Project
Native American Housing Block Grant, Formula - New construction, acquisition, rehabilitation including energy efficiency and conservation, and infrasturcture development.
Slocum Ridge III -Multifamily Housing Infrastructure Project
Native American Housing Grant, formula- New construction, acquisition, rehabilitation including energy efficiency items
IHBG Formula Amendment- Rehabilitation Activity for 32 rental units.  New construction of five single vamily home buyer units.
Oneida Tribe of Indians of Wisconsin Amendment Grant
To support the preservation of jobs that are threatened by declines in philanthropic and other support during the economic downturn.
Contractor was awarded ten (10) DTV Mobile Clinics and two (2) Walk-In Centers. DTV Mobile Clinics/ Walk-In Centers were put in place to educate the public on the transition from Analog to Digital; specifically targeting the groups that would b
The research objective of this award is to develop manufacturing technology enabling the fabrication of multi-material, near net-shape tissue engineering scaffolds for bone defect repair. This will enable a new class of functionally graded scaf
Customized Load-Bearing Scaffolds Using Multiscale Porosity and Multi-Material Domains
The proposed project is on approximation of operator functions, whose prototype in the case of functions of a scalar argument is the Taylor polynomial approximation. Values of operator functions do not commute in general, which makes the analys
FUNCTIONS OF OPERATORS ON HILBERT SPACES
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).    This project proposes research on two subjects: 1) Representation theory of W-algebras, 2) uniqueness properties for algebraic group actions. W
Headstart Cola and Quality Imporvement to low income children and their families. The Cola increase of 1.84% for Head Start program; these funds must be obiligated to pay staff salaries, fringes, and increase operating cost over the 12 month pe
SCHOOL BOARD OF CHARLOTTE COUNTY FLORIDA
This award provides for ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start and/or Early Head Start program. Charlotte County (Flori
WACCAMAW ECONOMIC OPPORTUNITY COUNCIL, INC.
THIS AWARD PROVIDES FOR ARRA COST OF LIVING ADJUSTMENT, AND QUALITY IMPROVEMENT FUNDING CONSISTENT WITH PROVISIONS OF SECTION 640 (A) (5) OF THE HEAD START ACT. HEAD START PROMOTES SCHOOL READINESS OF LOW-INCOME CHILDREN THROUGH THE PROVISION O
ARRA Cost of Living Adjustment (COLA) and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act. 159 children are served at Sining River Educational Association, INC in Lucedale MS in George Count
UNITED COMMUNITY ACTION COMMITTEE INC, THE
ARRA Cost of Living adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act.
PICKENS COUNTY COMMUNITY ACTION COMMITTEE, AND COMMUNITY DEVELOP MENT CORPORATION, INC.
Head Start 2009 ARRA COLA Quality Improvement Funding Not all funds will be expended
Head Start Quality  Improvement and COLA (ARRA): This award provides for ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640 (a)(5) of the Head Start Act for the Head Start and Ea
Head Start COLA, Quality Improvement funds.  A COLA increase of 1.84% for Head Start.These funds must be obligated to pay staff salaries,fringes over the 12 month period following the effective date of the grant. Funds shall be used for the fol
The ARRA funds were awarded to the UAB Early Head Start Program to help retain staff and enhance the program.  The UAB Early Head Start Program was funded in 1998 to serve 88 infants and toddlers and their families or women who are pregnant, wh
Head Start 2009 ARRA COLA Quality Improvement Funding Grant provides for a cost-of-living increase to employees in our EHS program that provides services to children up to age 3.  In addition the grant will cover staff travel, professional dev
ARRA Cost of Living Adjustment (COLA), and the Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act.  Playground equipment for outdoor play space.
ARRA  Cost of Living Adjustment (COLA) and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start and Early Head Start program. Both these programs promote the school readiness o
Head Start Expansion-RCMA will expand Head Start services: by providing full day, full-year services to 20 Head Start children and their families in our existing Farmworker Child Development Center located in Delray Beach, Palm Beach County, Fl
1. ARRA HEAD START EXPANSION: To expand Head Start services to 20 additional children. Awarded $13,400 in start up cost which were expended in the 2009/2010 grant period and the full awarded amount of $335,503 for the period of 9/30/09-9/29/11
This award provides for ARRA Head Start Expansion funding to serve an additional 36 children and families from 9/30/2009 through 9/29/2011. The Head Start program provides family-centered services for low-income families with young children (ag
Award Title: JCCEO ARRA Head Start Expansion Award Description and Purpose: The JCCEO ARRA Head Start Expansion Award provided funding to serve an additional 120 eligible children and families In Jefferson County, Alabama in a newly established
HEALTH & HUMAN SERVICES, NORTH CAROLINA DEPARTMENT OF
Copiah County Rest Area Site Improvements - I-55 North & South
This award provides for ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start and/or Early Head Start Programs.  Early Head Start prom
Head Start Quality Improvement and Quality (ARRA)  Purpose: Provide a COLA increase of 1.84% to all Head Start staff, add an Education Coordinator, and quality improvements to Head Start facilities and classrooms.
Head Start/Full Year Part Day Disabilities Training and Technical Assistance
This award provides a cost-of-living adjustment (COLA) increase of 1.84% for staff.  The award also provided quality improvement funds to the agency.  The quality improvement funds enabled the agency to repave the parking lots at the Warren Wes
Head Start:  Full year Part Day Handicapped Training & Technical Assistance
COMMUNITY ACTION OF EAST CENTRAL INDIANA INC
ARRA Cost of Living Adjustment (COLA), Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act CAECI Head Start serves 306 children in a part-day, part-year program in Wayne County Indiana.  The chi
COMMUNITY ACTION OF NORTHEAST INDIANA INC
COLA, Employee Education including a Spanish and a Mental Health class for staff seeking a bachelor degree, Quality Improvement included roof tape for one building to prevent ice build-up, four new playgrounds, family service staff attendance a
Head Start: Full Year Part Day Handicapped Training & Technical Assistance
COMMUNITY ACTION ORGANIZATION OF SCIOTO COUNTY, INC
ARRA COST OF LIVING ADJUSTMENT (COLA), AND QUALITY IMPROVEMENT FUNDING CONSISTENT WITH THE PROVISIONS OF SECTION 640(a)(5) OF THE HEAD START ACT.  This grant awarded funds made available to the Federal Head Start program - 05SE4044.  This actio
W. S. O. S. COMMUNITY ACTION COMMISSION, INC.
This awards a cost of living adjustment (COLA) increase of 1.84% in the amount of $90,062 for Head Start and $9,688 for Early Head Start.  The COLA increase will grant wage increases in the amount of 1.84% to all Head Start and Early Head Start
This award provides for ARRA Cost of Living Adjustment (COLA) and Quality Improvement funding consistent with the provisions of Section 640 (a)(5) of the Head Start Act for the Head Start and Early Head Start programs.  Head Start and Early Hea
Head Start/Early Head Start COLA and Quality Improvement
This award provides for ARRA Cost of Living Adjustment (COLA) and Quality Improvement funding consistent with the provisions of Section 640 (A) (5) of the Head Start Act for the Head Start Program. Head Start promotes the school readiness of lo
HEAD START: FULL DAY PART DAY HANDICAPPED TRAINING & TECHNICAL ASSISTANCE
HEAD START FULL YEAR PART DAY TRAINING AND TECHNICAL ASSISTANCE, NUMBER OF CHILDREN TO BE SERVED-320, DOUBLE SESSION CENTER BASED PROGRAM-4 DAYS PER WEEK. HEAD START IS A FAMILY-CENTERED PRESCHOOL PROGRAM DESIGNED TO PROVIDE EDUCATION, SOCIAL S
HEAD START CHILD AND FAMILY DEVELOPMENT CENTERS, INC.
ARRA Cost of Living Admustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)of the Head Start Act
Head Start Full Year Part Day Handicapped Training and Technical Assistance (this is the project/program title included on our Financial Assistance Award).  This award includes ARRA funding for cost of living adjustments (COLA) and quality impr
ARRA Cost of Living Adjustment (COLA)and Quality Improvement Funding consistent with the provisions of Section 640(a)(5)of the Head Start Act
COMMUNITY ACTION PROGRAM COMMISSION OF THE LANCASTER FAIRFIELD COUNTY AREA
This award provides for ARRA Cost of Living Adjustment (COLA) and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start and Early Head Start programs.  Head Start promotes the s
Head Start funding increase provided through ARRA Cost of Living Adjustment (COLA) in the amount of $24,738 (1.84%) and Quality Improvement (QI) award funds in the amount of $74,830 consistent with the provisions of Section 640(a)(5) of the Hea
FAMILY AND CHILD LEARNING CENTERS OF NORTHEAST WISCONSIN, INC.
ARRA Cost of Living Adjustment (COLA) and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act.   ARRA COLA and Quality Funds will be used to increase compensation of all Head Start and Early Hea
COLA, ARRA AND QUALITY IMPROVEMENT FOR HEAD START AND EARLY HEAD START.
The Head Start ARRA funds provided the opportunity for staff to raise the qualifications of Teachers, Assistant Teachers, Family Service Workers and other essential Head Start staff by providing professional development through college credit o
HEAD START: FULL YEAR PART DAYHANDICAPPED TRAINING AND TECHNICAL ASSISTANCE
COOPERATIVE EDUCATIONAL SERVICES AGENCY # 2
This action is a cost-of-living adjustment (COLA) increase of 1.84% in the amount of $36,101 for Head Start.  This action also awards quality improvement funds of $108,087 for Head Start.
1) ARRA Cost of Living and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act. 2)Number of children served is 1,233. 3)Program Options offered are Full-day Center based, Half-day Center based a
CHILDREN'S HOME & AID SOCIETY OF ILLINOIS
Early HeadStart ARRA COLA (cost of living adjustment) and QI (quality improvement) Funding for Early Head Start Staff. The Early Headstart program provides family-centered services for low-income families with very young children (birth to 3) t
Dane County Parent Council's Head Start ARRA Expansion Flexible Full Day Model has a focus on Latino families & young children. Head Start provides preschool education and full day child care for 36 additional children and at risk low income fa
Water and waste disposal loan to the Defiance County Board of Commissioners.
Defiance County Board of Commissioners - Auglaize River Sewer Collection and Treatment Project
Economic Adjustment Grant to fund a Cluster Acceleration Program that provides critical business knowledge, resources and relationships to Illinois-based entrepreneurial ventures with high potential for sustainable growth, profitability and job
Guardrails West of Hillcrest Drive to West of US 40 Scenic
COMMUNITY ACTION PROJECT OF TULSA COUNTY, INC.
ARRA Headstart Expansion to serve 135 children. The program provides family centered services for low income families with preschool age children to promote school readiness.
Award  to fund cost of living adjustment, partial cost of hiring a bilingual teacher, supplies. Materials, and training for bilingual teacher, supplies and equipement to set up a kitchen at the Head Start Campus.
MOREHOUSE COMMUNITY IMPROVEMENT ORGANIZATION INC, THE
This award provides for ARRA Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start and/or Early Head Start program.  Head Start promotes the school readiness of low-income child
Head Start Discretionary Grant.  These funds will be utilized for CDA certification training for staff members and towards the purchase of anoutdoor paly structure which will meet the requirements for access under the Accessibility Guidelines f
Through the American Recovery and Reinvestment Act, Total Community Action, Inc. Head Start was awarded Supplemental Funds for Cost of Living (COLA) and Quality Improvements (QI).  Total Community Action, Inc. Head Start services over 1,500 chi
This award is for a Cost of Living Adjustment (COLA) increase of 1.84%  for all Head Start and Early Head Start staff and Quality Improvement Funds for Head Start and Early Head Start programs.
SOUTHEAST NM COMMUNITY ACTION CORPORATION
Head Start This award provides for ARRA Cost of Living Adjustment (COLA) and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start program.  Head Start promotes the school readi
ARRA COLA and Quality Funds are being used for staff development, supplies, minor renovations, COLA, and the addition of one Education Specialist
SOUTHEAST ARKANSAS COMMUNITY ACTION CORPORATION
Provide a 1.84% salary increase to all Head Start employees, purchase a copier, hire 2 staff and make improvements to t Head Start centers.
ARRA Cost of Living (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act.  WILL IMPROVE COMPENSATION/BENEFITS OF EDUCATION PERSONNEL AND FAMILY ADVOCATES, EXTEND STAFF DAYS OF EMPLOYM
This award provides for ARRA Cost of Living Adjustment(COLA) and Quality Improvement Funding for the Head Start and Early Head Start Programs.  The Quality Improvement Funding will improve components of child safety and better equip teachers &
COMMUNITY COUNCIL OF SOUTH CENTRAL TEXAS, INC.
This award provides for ARRA Cost of Living Adjustment (COLA), and Quality Improvement  Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start program.  The award provided a 2.33% enhancement of sal
ARRA Cost of living adjustment and quality inmprovement funding consistent with the provisions of section 604(a)(5) of the Head Start Act. Enhanced training equipment and safety features also included
HEAD START QUALITY IMPROVEMENT AND COLA (ARRA) GRANT NUMBER: 06SE7015
HHS ARRA Head Start funding for Cost of Living Adjustment (COLA) and Quality Improvement (OI) consistent with the provisions of Section 640(a)(5) of the Head Start Act
Head Start Expansion  Description The Hidalgo County Head Start Program will provide increase Head Start services to120 additional low income children and families in Hidalgo County. Six (6) classrooms will be constructed and one additional cla
US 101 & SR 109/Myrtle to Endreson & US 101 to Eisenhower - ADA work
Kuhio Highway Resurfacing, Kawaihau Road to Kapaa Bridge
U.S. Department of Commerce, Economic Development Administration Economic Adjustment Grant to establish a Revolving Loan Fund (RLF).  This grant is to establish a statewide RLF to help Montana businesses in the wood products industry retain and
Economic Adjustment Grant to Establish a Revolving Loan Fund
HOUSING AUTHORITY OF THE CITY OF PINE BLUFF
Public Housing American Recovery Act Stimulus Funds
The CR-SDC Head Start Program serviced 2887 low-income children throughtout Milwaukee County. The program serves children in a predominately center based, double session program but includes one home based caseload of 12 children. Head Start pr
ARRA COLA AND QI funding consistent with the provisions of Sec. 640(a)(5)of the Head Start Act.
COMMUNITY ACTION PROGRAM OF EVANSVILLE & VANDERBURGH COUNTY INC
ARRA Cost of Living Adjustment (COLA) and Quality Improvement Funding consistent with the provisions of section 640
This award provides for Head Start COLA (cost of living adjustment)and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start program.  Head Start promotes the school readiness of low-income children t
COMMUNITY ACTION COMMISSION OF BELMONT COUNTY
HEAD START:  FULL YEAR, PART DAY, HANDICAPPED - TRAINING AND TECHNICAL ASSISTANCE
ASHTABULA COUNTY COMMUNITY ACTION AGENCY PROPERTIES CORPORATION
ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a) (5) of the Head Start Act for the Head Start and Early Head Start program. Head Start promotes school readiness of low-incom
WEST CENTRAL MINNESOTA COMMUNITIES ACTION, INC.
This award provides for ARRA Cost of Living Adjustment (COLA) and Quality Improvement Funding consistent with the provisions of Sec. 640(a)(5) of the Head Start Act for the Head Start program.
This award provides for ARRA COLA and QI funding cosistent with the provisions of Section 640(a)(5) of the Head Start Act. Head Start promotes the school readiness of low-income children through the provision of comprehensive health, developmen
Awards a cost of living adjustment (COLA) increase to all Head Start staff during the contract period.  Also awards the program quality improvement funds to be used during the contract period.
G M N TRI COUNTY COMMUNITY ACTION COMMITTEE
GMN Tri-County CAC, Inc. Head Start provides full-year, part-day, and combo-option services to 401 children and families in Guernsey, Monroe, and Noble Counties in Ohio.  These services include; health, nutrition, mental health, disability, soc
Head Start: Full Year Part Day Handicapped Training And Technical Assistance
Head Start - a comprehensive early child development program for three to five year olds and their families that live in Lenawee County.
HEAD START: FULL YEAR PART DAY HEANDICAPPED TRAINING AND TECHNICAL ASSISTANCE
HEADSTART EARLY CHILDHOOD EDUCATION FOR CHILDREN FROM LOW INCOME FAMILIES. PROVIDES QUALITY EARLY CHILHOOD LEARNING ESSENTIAL FOR ACADEMIC ACHIEVEMENT WHEN CHILDREN PROGRESS TO ELEMENTARY SCHOOL, AND ASSISTS FAMILIES IN SUPPORTING ACADEMIC ACHI
HEADSTART: FULL YEAR PART DAY HANDICAPPED TRAINING & TECHNICAL ASSISTANCE
COMMUNITY ACTION COMMISSION OF FAYETTE COUNTY
Provides ARRA Cost of Living Adjustment (COLA) & Quality Improvement Funding consistent with provisions of Section 640(a)(5) of the Head Start Act.  Head Start promotes the school readiness of low-income children through the provision of compre
CHILD DEVELOPMENT SERVICES OF OTTAWA COUNTY, INC.
This award provides for ARRA Cost of Living Adjustment (COLA) and Quality Improvement Funding consistent with the provisions of Section 640(a) (5) of the Head Start Act for the Head Start and Early Head Start program.  Head Start promotes the s
NORTHEAST MICHIGAN COMMUNITY SERVICE AGENCY, INC.
HS/EHS ARRA COLA of 1.84% for staff over 12 month period & for Quality Improvement funds for both Head Start & Early Head Start.
HEAD START:  FULL YEAR PART DAY HANDICAPPED TRAINING AND TECHNICAL ASSISTANCE: Cost of Living Adjustment (COLA) for  Head Start staff salaries and quality improvement for Head Start program, site improvements, classroom supplies and equipment.
This action awards a cost-of-living adjustment (COLA) increase of 1.84% in the amount of $52,244 for Head Start and $18,904 for Early Head Start.  These funds must be obligated to pay for staff salaries over the 12-month period following the ef
Head Start & Early Head Start- Full Day, Part Day
This award provides for ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with provisions of section 640(a)(5)of the Head Start Act for the Head Start and/or Early Head Start program.  The Early Head Start progra
This award provides for ARRA Head Start Expansion funded to serve 87 children in Eaton, Ingham, and Shiawassee counties.  The Head Start program provides family-centered services for low-income families with young children (3 to 5 years) to pro
Head start ARRA Expansion for 30 children.The Head Start Expansion grant serves 30 children in a center based option.  The cities served are Hoopeston in Vermilion County and Gibson City in Ford County, Illinois.  The Head Start program provide
Head Start Expansion in Hoopeston, Vermilion County, and Gibson City, Ford County
Head Start ARRA Expansion project to provide additional 39 center based and 10 home based slots for 3 to 5 year old children.  Center based children attend half day sessions at a neighborhood elementary school site.   A teacher visits families
SR 438 From Hwy 61 through Arcola to Hwy 1
Luce County Industrial Park Expansion.  Water, Sewer, Roads and Railroad.
Resurfacing from Evitts Creek Bridge 0103000 to Rocky Gap Road Bridge 0115100
El Grito, Inc. is a federally funded non-profit head start program that provides quality full day educational and childcare services to 184 low income children and families in rural Grant County, New Mexico. Our goal is to break the cycle of po
ARRA Cost of Living Adjustment(COLA) & Quality Improvement Funding consistant with the provisions of Section 640(a)(5)of the Head Start Act
THIS HEAD START QUALITY IMPROVEMENT AND COLA (ARRA) PROJECT WAS AWARDED FOR THE BUDGET PERIOD 07/01/2009 THRU 09/30/2010, AND WAS MADE UP OF TWO MAIN ELEMENTS.  THE FIRST ELEMENT WAS A NON-PERMANENT 1.84% COLA WHICH WHICH BENEFITED THE CURRENT
CHILD DEVELOPMENT COUNCIL OF BRAZORIA COUNTY
This award provides for ARRA Cost of Living Adjustment (COLA), for Head Start and Early Head Start staff salaries and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for Head Start and Early
Head Start promotes the school readiness of low-income children through the provision of comprehensive health, developmental and family services. St. James Parish Head Start serves the low-income three- and four-year-old children of St. James P
We are a Head Start and Early Head Start Progam-Neighbors In Need of Services, Inc and were approved for this one-time funding under the ARRA Quality and Improvement Fund.  As approved by the Department of Health and Human Services and under th
Head Start Cola and QIP Quality improvement increases will help meet new staff requirements of the Head Start Act.  Education Staff will have the opportunity and financial support to pursue education, training, and career development that will
Quality improvement funding in the amount of $38,549 will be used to provide training and technical assistance, sustain ongoing monitoring efforts, build and sustain a Fatherhood inititative and provide materials and supplies to the 3 efforts m
This award provides for ARRA Cost of Living Adjustment (COLA), Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start Head Start promotes the school readiness of low-income child
AMERICAN RECOVERY AND REINVESTMENT ACT OF 2009 HEAD START PROGRAM PROMOTES SCHOOL READINESS OF LOW-INCOME CHILDREN THROUGH THE PROVISION OF COMPREHENSIVE HEALTH DEVELOPMENT AND FAMILY SERFICES. ARRA FUNDS SERVED APPROXIMATELY 388 STUDENTS OF TH
ARRA Cost of Living Adjustment and Quality Improvement Funding consistent with the provisions of Section 640 (a)(5) of the Head Start Act.  The grant awards a cost of living adjustment of 1.84% to staff salaries that was paid over a 12 month pe
Discretinary grant awarded through ARRA privdes a 1.84% COLA increase for Head Start staff during the 12 month perod of the contract. The COLA increase makes it possible to extend classroom operation for one week. ARRA COLA awards funding for q
AVOYELLES PROGRESS ACTION COMMITTEE, INC
This award provides for ARRA Cost of Living Adjustment(COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start Program. Head Start promotes the school readiness of low-
OUACHITA MULTI-PURPOSE COMMUNITY ACTION PROGRAM, INC.
Ouachita Multi Purpose Community Action Program offers quality social health and educational services to 771 low-income children ages 3 to 5 years old who reside in Ouachita Parish.
Award Title: American Recovery and Reinvestment Act Discretionary Head Start Grant. This award provides for ARRA Cost of Living Adjustment (COLA), and Quality Improvement (QI) Funding consistent with the provisions of Section 640(a)(5) of the H
Head Start award.  Head Start promotes the school readiness of low-income children through the provision of comprehensive health, developmental and family services.  This award funds a cost of living adjustment and awards quality improvement fu
ARRA Quality Improvement Funds for center-based Head Start program serving 807 Children in Bryan, Carter, Coal, Love and Pontotoc Counties.  Head Start is a Federal program for preschool children from low-income families. The Head Start program
This action awards a cost-of-living adjustment (COLA) increase of 1.84% in the amount of $42,773 for Early Head Start. These funds must be obligated to pay for staff salaries over the 12-month period following the effective date of this grant o
NORTH TEXAS PARENT & CHILD DEVELOPEMENT INC
These funds are used for COLA raises, education for employees, enhancing playground safety for the children we serve.  These funds are used to bring in consultants to train staff on the latest issues.
Head Start / Early Head Start ARRA Grant - This grant is for a cost-of-living adjustment increase of 1.84% for a 12 month period. This grant also awarded Quality Improvement funds to purchase playground structures for Head Start and Early Head
Highway N-71, Nebraska/Colorado Line North
CR67 REHAB & RESURF - LIE SERV RD TO CR17
General Jim Moore Boulevard Phase V and Eucalyptus Road Phase II
This ARRA investment funds are for the expansion of a dock and an installation of a crane. The expansion will increase the number of fishermen able to use the dock and increase their income. The investment will help create 75 jobs, save 200 job
Phase I Crane Installation/Phase II North Bulkhead Extension
Construction of approximately 1.25 miles of water and sewer lines, storm drains, and street improvements to support the development of the Imperial Center, a 77-acre new multi-use commercial development near the intersection of Highway 86 and H
US 45 A FM WEST POINT TO 1 MI N OF SR 25
US 45 A FM THE S MON CL TO THE N MON CL & US 45A FM NEAR SR 8 TO THE CHICK LN
SR 331 REPLACE BRIDGE BT CALHOUN C.L. & SR 334
The broad goal of this research is to use engineering approaches to identify fundamental mechanisms and biological design rules that control the assembly and stability of intercellular junctions in tissues. This research focuses on a class of p
To identify the source of pollutants once they reach receiving water is one of the major problems of nonpoint-source pollution management. The principal objective of this project is to develop a tracer-system for identifying and characterizing
: USING NANOTECHNOLOGY TO IDENTIFY POLLUTION SOURCES IN THE LANDSCAPE
Plasmon resonance, an optical phenomenon associated with metal nanoparticles, is being investigated for biomedical imaging and intervention at the cellular level. However, the size requirements for complete elimination of currently available na
Degradable plasmon resonant gold nanoshells
Advanced fuel injection strategies are central to efforts to improve the performance and emissions characteristics of internal combustion engines.   Existing fuel injectors severely restrict the strategies that can be explored, however, because
Variable Geometry Spray Fuel Injection: Investigating its Effects on Combustion Efficiency and Emissions
The PI will explore three related projects in total positivity, cluster algebras, and statistical mechanics. The first project seeks to develop and apply combinatorial tools to the study of totally positive varieties; in particular, to understa
Total Positivity: Connections with Alegebra, Topology, and Statistical Physics
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  The project seeks continued support of investigations of the polar mesosphere, thermosphere, and ionosphere over Sondrestromfjord through coordin
Joint Incoherent Scatter Radar and Electro-Optical Remote-Sensing of the Effects of Auroras as well as Planetary, Tidal and Gravity Waves in the Polar Thermosphere over Sondrestrom
Neutrinos offer a new way to look at the sky. As a new generation of experiments is being developed, the detection of neutrinos from core collapse supernovae and stellar jets finally is within reach, with unprecendented potential to learn about
Number theory has seen many significant advances in the past few years.  Results from arithmetic geometry and the theories of modular forms and  Galois representations have yielded a proof Fermat's Last Theorem, a proof  of Serre's modularity c
FRG: COLLABORATIVE RESEARCH: AUTOMORPHIC FORMS, GALOIS REPRESENTATIONS, PERIODS, AND P-ADIC L-FUNCTIONS
FRG: Collaborative Research: Automorphic forms, Galois representations, periods and p-adic L-functions
This project will use ultra-cold atoms trapped in an optical lattice to explore thermopower in the Hubbard model. Thermoelectric (TE) materials will play a key role in near- and long-term reliable methods for efficient power generation and cool
Simulating Thermopower in Mott-Hubbard Materials
The proposed project will turn the wireless emulator testbed into a shared community resource.  The project has three thrusts. First, we propose to make two professionally-supported wireless emulator testbeds available as the core of a communit
CI-ADDO-EN: A Community Testbed for Controlled and Repeatable Wireless Experiments
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). Buggy software costs the U.S. up to $60 billion annually, so preventing bugs is important to society. It is possible to prevent certain bugs by ru
II-NEW:  Practical Pluggable Type Systems
The objective of this study is the development, characterization and utilization of a ?sensate? cartilage covered scaffold that replaces the load bearing area of a joint. Load measurements from this implant will facilitate development of better
SENSORS: In Vivo Joint Regeneration Monitoring System to be able to Establish Rehabilitation Approaches during Healing
The protons and neutrons that serve as building blocks for our visible universe are constructed from smaller, more fundamental particles called quarks and gluons. These point-like particles, or partons, are confined inside nucleons due to the n
Fundamental Studies of the Nucleon Spin in QCD
'This project covers a program of research in ''Fundamental Studies in Nuclear Physics'' at the Kellogg Radiation Laboratory of the California Institute of Technology. It includes primarily experimental research addressing key issues in nuclea
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). This award provides continuing support for a program of research for the High Energy Physics group at the University of Washington. This group is
Elementary Particle Physics Using High Energy Colliders
This Award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  TECHNICAL SUMMARY:  Sn-based alloy coatings have been used for many years in the manufacture of electronic components to enhance solderability an
Whisker Formation in Sn Coatings on Cu: Fundamental Mechanisms and Approaches to Mitigation
Recent measurements of the Bering Strait throughflow fluxes find strong seasonal and interannual variability, so far unpredictable ? the heat flux increase from 2001 to 2004 is enough to melt an 800 km by 800 km area of 1 m thick ice, and the i
Collaborative Research: An Ocean Observing System for the Bering Strait, the Pacific Gateway to the Arctic - an integral part of the Arctic Observing Network
Rehabilitation of the Industrial Drive Bridge No. 882
This task order is for construction observation assistance during construction of improvements to facilities of the Methow Valley Irrigation District - East (MVID-E) in the Methow River Subbasin near Twisp, WA
The Poudre School District Early Childhood Program was awarded for both COLA and Quality Improvements Grant for Head Start and Early Head Start. PSD has identified the ARRA COLA to assist in providing salary increases to all staff. The PSD Huma
1. ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act. 2. 268 Head Start Children - 121 Early Head start Children 3. Home base and Center based progra
HEAD START 2009 ARRA COLA QUALITY IMPROVEMENT FUNDING.  In the past years, due to being a part of a school district, the Head Start employees received an overall average of a 3.43% COLA increase, while Head Start allocated an average of a 1.5 %
Cost-of-living adjustment for Head Start and Early Head Start staff salaries and quality improvement funds to increase the number of weeks providing services to Head Start children. This is consistent with the provisions of Section 640(a)(5) of
HEAD START 2009 ARRA/COLA/QUALITY IMPROVEMENT FUNDING. COST OF LIVING ADJUSTMENT INCREASE OF 1.84% IN THE AMOUNT OF $10,361.00 FOR ALL STAFF AT HEAD START. FUNDS TO PAY FOR STAFF SALARIES OVER A 12 MONTH PERIOD. REMAINDER OF FUNDS ARE FOR INCRE
This award provides for ARRA Cost of Livig Adjustment and Quality Improvement Funding consistent with the provisions of section 640(a)(5) of the Head Start Act for the Head Start program.  Head Start promotes the school readiness of low-income
1. 2009 ARRA COLA $7,911  2. ARRA Quality Improvement Funds (a) $8,647 and (b) $8,646 = $17,293  Total ARRA COLA & QI = $25,204
ARRA Cost of Living Adjustments (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act
Replace HVAC units in rental and community buildings, replace fencing and plumbing systems and electrical systems in community facilities
HVAC Upgrades, Fence Electrical & Plumbing Replacement
Plumbing, Heating, and Air-Conditioning Contractors
Utilizing ARRA funding allocated through IHBG formula, TNHA will address two areas of critical need: 1) TNHA will modernize seventy-five (75) 1937 Act housing units. Replacement of outdated and inefficient heating systems will assume priority.
American Recovery and Reinvestment Act of 2009 (Recovery Act), Fiscal Year 2008 Indian Housing Plan (IHP). Amendment Number 08SH0201120.
2008 SANTA YNEZ ARRA - FORMULA (Access Roads/ Errosion Control)
The projects selected for the Recovery Act funding were selected according to the needs that have been observed by SIRHA Staff and the Board of Commissioners. SIRHA'S projects for the Recovery Act funding are as follows: 20 Low Rent Homes will
Susanville Indian Rancheria Housing Authority
Modernization of Native American housing
Modernazation of Native American Housing
2008 Viejas ARRA - Formula (Soil Erosion Control/Install Membranes (water well)/ Well Maintenance)
Soil Erosion Control/Install Membranes (water well)/ Well Maintenance
Native American Housing Block Grant - Forluma.  The Eligible Activity is New Construction of Rental Housing and we are creating new affordable rental units.
Native American Housing Block Grant, Formula-New construction, acquisition, rehabilitation including energy efficiency and conservtion, and infrastructure development.
Rehab low income rental units to energy star rated window and doors and low income elderly handicap accessibility and weatherization.
TE MOAK TRIBAL WESTERN SHOSHONE HOUSING AUTHORITY
The Housing Authority shall modernize low income program units that are part of its formula current assisted stock in compliance with Section 202(1) of the Native American Housing Assistance and Self Determination Act (NAHASDA).  The Housing Au
Infrastructure for forty lots to low income families.
Funds to be used for the rehabilitation of existing rental housing and home ownership units of the Comanche Nation Housing Authority to further our mission of providing affordable, safe and decent housing to low income familities.
HOUSING AUTHORITY OF THE SAC AND FOX NATION, THE
1.1 Purchase by acquisition two units for rental. Construct two units for rental. 2.1 Provide additional training opportunities for staff and Board of Commissioners.  Provide all administrative functions for efficient operations.
1.1 Purchase by acquisition two units for rental. Construct two units for rental.
The Housing Authority shall modernize low-income program units that are part of our formula current assisted stock in compliance wiht Section 202 (1) of the Native American Housing Assistance and Self Determination Act.
Native American Housing Block Grant, Formula-New Construction, acquisition, rehabilitation including energy efficiency and conservation, and infrastructure developement.
Raven Crest Addition Single-Family Housing Construction Project
RED CLIFF BAND OF LAKE SUPERIOR CHIPPEWA INDIANS
IHBG increase intended to supplement 24 new home LIHTC project and rehab of existing FCAS.
Native American Housing Block Grant Formula-rehabilitation including energy efficiency and conversion.
New Construction of Low-Income Rental Housing
Plumbing and Heating Equipment and Supplies (Hydronics) Merchant Wholesalers
Native American Housing Block Grant, formual-new construction
KNIK TRIBAL COUNCIL NONPROFIT CORPORATION
Indian Reservation Roads Program, funds used in the implementation of preconstruction p,lanning and design of chief wasilla way road.
The Pascua Yaqui Housing Department is currently demolishing existing homes for reconstruction of Tribal homes on the New Pascua Reservation.  These homes are considered low-income and very substandard.  The award of the recovery act funds for
Tribal Renovation/ New Construction Project (on-reservation)
Native American Hoousing Block Grant (formula) Recovery Act Fund to rahabilitate houses and construct office and storage area for maintenance staff and materials.
Rehabilitation for Energy Efficiency & Conservation  ARRA Funds
NATIVE AMERICAN HOUSING BLOCK GRANT, FORMULA- COMMUNITY BEAUTIFICATION
Formula Grant-Rehabilitation of existing housing units
NATIVE AMERICAN HOUSING BLOCK GRANT FORMULA
REHABILITATION OF AFFORDABLE HOUSING UNITS
The Yomba Shoshone Tribe will construct a Maintenance & Storage Building to store all the maintenance equipment, inventory supplies, and provide lockable and workable building for the force account and maintenance crew to conduct their work, re
Acquisition with rehabilition for home buyers; identify and purchase 13 preowned homes to (1) reduce over crowding (2) assist renters to become homeowners (3) improve quality of substandard units.
2008 ARRA  Parkview Manor Apartment Acquisition & Rehabilitation Project
Native American Housing Block Grant, Formula - infrastructure development.  Demolish structure(s) on project site and install water & sewer lines to serve 6 single-family detached low-income rental units at 38010 SE North Bend Way, Snoqualmie,
Contractor shall provide a static walk in help center and mobile help centers to assist consumers to successfully make the transition to DTV from over-the-air television by providing hands-on demonstrations and reading fact sheets and other pri
In the last few years, Huang has proved the Verlinde conjecture and the Verlinde formula which play a fundamental role in Conformal Field Theory and related subjects and has proved the rigidity and modularity of the ribbon category of modules f
Two Dimensional Conformal Field Theories and Their Moduli Space
The objective of this research is to develop a process which integrates high performance thin film silicon circuitry with compound semiconductor devices, and to use this process to demonstrate an active matrix light emitting diode capable of pr
A new Approach to Silicon/Compound Semiconductor Integration
The methods of p-adic Hodge theory have emerged as a powerful tool for studying Galois representations arising from algebraic varieties over p-adic fields. This proposal investigates integral p-adic Hodge theory, which is the study of integral
Integral p-adic Hodge Theory and its Application to Automorphic Forms
With regards to the intellectual content of the project, the aim of this proposal is the study of interactions between quasiconformal (QC) mappings, geometric analysis (in particular uniform rectifiability), Fourier analysis, and geometric comb
Geometric and Combinatorial Viewpoints in Complex and Harmonic Analysis
The Principal Investigator will conduct research on applications of algebra-geometric methods to Asymptotic Group Theory. The main goals of this project are twofold. One objective is to show that some group theoretic invariants (representation
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). The project will investigate interactions between differential geometry and nonlinear partial differential equations. In particular, it will explo
Hessian and Special Lagrangian Equations
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  This award will support a study that addresses the hypothesis that the expanding extent and duration of seasonal open water in the Arctic has the
Collaborative research: Impacts of the changing seasonality of wind-driven mixing on the Arctic system
The objective of the research will be to advance the science and technology of visible LEDs fabricated from columnar nanostructures that emit at visible wavelengths and with high efficiencies.  Intellectual Merit of the Program  A program of re
Nanostructure Visible Light Emitting Diodes
within protons, neutrons, and other particles by exploring the role of gluons, the particles that bind these quarks together.  Consistent with the goals of the RUI program, education of undergraduates and masters-level students is a central co
RUI:  Studies of Nucleon Structure Using Electromagnetic Probes at Jefferson Laboratory
It will provide funds for this group to work on Milagro, a TeV cosmic gamma ray experiment, and HAWC, a successor to Milagro. Very high energy gamma ray astronomy probes some of the most extreme environments in the known universe. Known sources
Particle Astrophysics with HAWC and Milagro
The CCDF ARRA funds will be used to provide child care financial assistance to low-income working families and fund activities to improve the quality of child care. Th majority of the funds supported the child care assistance program and the ta
ARRA Supplemental Funding for the Child Care Devlopment Fund (CCDF)
Improved Access: $30 1/3 Income Disregard The Missouri Child Care Assistance Program served 397 (unduplicated) households through the $30 1/3 Income Disregard program for this quarter.  A total of 694 (unduplicated) children were served.  The t
Child Care and Development Fund Stimulus
HOUSING & COMMUNITY AFFAIRS, TEXAS DEPARTMENT OF
The CSBG ARRA award is Recovery Act funding for the Community Services Block Grant.  The purpose of the program is to provide supplemental funds for job preservation, infrastructure investment, energy efficiency and science, assistance to the u
This proposal is composed of five broad research topics in algebraic, geometric and topological combinatorics.  The first project is to expand results about the strong Bruhat graph of Coxeter systems to the more general setting of balanced grap
Bruhut and balanced graphs, manifolds, partitions, and affine permutations
PRESIDENT AND FELLOWS OF MIDDLEBURY COLLEGE
There is increasing evidence that ecological processes at high latitude are just as sensitive to the timing of events as to their magnitudes. In the boreal forest, moisture availability in summer affects both tree growth and the fire regime. Su
RUI/Collaborative: How the Timing of Summer Precipitation Affects the Responses of Boreal Forest to Climate Change
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  An understanding of how climate in California responds to global and regional forcing mechanisms on multiple timescales is crucial for the manage
Reconstructing climate variability and aridity in the Sierra Nevada, CA, based on isotopic evidence in sediments from Swamp Lake, Yosemite
The group will test hypotheses concerning how temporal and spatial variability of Southern Hemisphere climate compared with the Northern Hemisphere during the Holocene. This research will help resolve drivers of paleoclimate by providing a pers
Collaborative Research: A Southern Hemispheric Perspective on Holocene Climate Variability Based on Mountain Glacial Chronologies
STANDING ROCK HOUSING LOCAL DEVELOPMENT CO
American Recovery and Reinvestment Act of 2009.  Award is to assist with modernization of 57 homes. This modernization is to help to provide energy efficient homes.
Native American Housing Block Grant, Formula-New Construction, acquisition, rehabilitation including energy efficiency and conservation and infrastructure development.
Native American Housing Block Grant, Formula-New Construction, Acqusition, Rehabilitation Including Energy Efficiency .
ALABAMA COUSHATTA INDIAN HOUSING AUTHORITY
The program under the Recovery Act is to augment current efforts in progress to curtail expansion of the initial damages from a hurricane, reduce fire hazards from electrical deficiences, and upgrade homes that have sustained widespread damages
HSG Auth Alabama Coushatta (TX338) Indian Housing Block Grant (IHBG)
Hoh River Housing Site Development Project
Native American Housing Block Grant, Formula - New construction, acquisition, rehabilitation including energy efficiency and conserfation, and infrastructure development.
Quinaielt Village Single-Family Rental/LIHTC Housing Projet
Native American Housing Block Grant Fromula-rehabilitation including energy efficiency and conservation.
Native American Housing Block Grant formula-rehabilation inclusing energy efficiency and conversions.
Rehabilitation Assistance to existing homes
Planning, administration and renovation of low-income homes to improve the quality of substandard and overcrowded units with Tribal jurisdiction.
Rehabilitation assistance to existing home owners
Native American Housing Block Grant Formula New Housing Construction
Handicap accessability and energy efficiency
The Department of Community Housing has developed activities under the Recovery Act to improve the current conditions of older 1937 Housing Act units by renovating them for the purpose of safety, health and extending the life of the units, to p
1).  Landscape & Modernize Exteriors of 1937 Housing Act Rental Units  2).  1937 Housing Act Rental Unit Demo/Reconstruct 3).  Construction of Infrastructure - Sacate Subdivision
To provide with the assistance of the construction of 1 house and Housing Rehabilitation for low-income eligible tribal members.
BEAR RIVER BAND OF ROHNERVILLE RANCHERIA
Native American Housing Block Grant, Formul - New Housing Construction
Native American Housing Block Grant, Formula - New construction, acquisition, rehabilitation including energy efficiency and conservation and infrastructure development
Modernization and acquisition of low-income housing
LITTLE TRAVERSE BAY BANDS OF ODAWA INDIANS
To construct one to two new homes for purchase at Wah Was Noos Da Ke Tribal Village.
Native American Housing Block Grant, formula-new construction, acquisition, rehabilitation, including energy efficiency and conservation, and infrastructure development.
FDL Housing constructed a 24 unit permanent supportive housing complex consisting of 4 three bedroom apartments, 10 two bedrooms, 6 one bedroom units and 4 efficiencies along with a playground area, office space for the Human Services case mana
Construct 5 rental duplexes (10 units) construct storage building
NPHB Formula New Construction FEMA Units
Native American Housing Block Grant, Formula, New Construction, Acquisition, Rehabilitation including energy efficeincy and infrastructure development.
Native American Housing Block Grant, Formula, Recovery Act Funded
CONFEDERATED TRIBES OF SILETZ INDIANS, THE
Siletz Tribal HOusing Low Income Rentals
The objectives of this Grant Opportunity for Academic Liaison with Industry (GOALI) research project are to improve understanding of pulsed laser micro polishing and to develop strategies for delivering pulsed laser energy to three-dimensional
ARRA GOALI: Automated Laser Micro Polishing System for Meso/Micro Engineered Parts/Devices
The expressive power of nonlinear programs allows the formulation of a remarkable number of application problems from business, science, engineering, and economics. In the presence of nonconvexity, global optimization of such programs poses unm
Collaborative Research: Generating Stronger Cuts for Nonlinear Programs via Orthogonal Disjunctions and Lifting Techniques
The research objective of this award is to advance the manufacture, the fundamental understanding, and the device application of graphene-nanocrystal metamaterials or hybrid graphene-nanocrystal structures, i.e., graphene sheets with discrete n
Colloborative Research: Exploration of Graphene-Nanocrystal Metamaterials
The PI's research is centered on functional analytic aspects of harmonic analysis. This project is devoted to understanding real-Hardy spaces and the Littlewood-Paley theory in the noncommutative setting. The PI will apply the results to operat
Noncommutative Hardy Spaces and Littlewood-Paley Theory
The proposal focuses on the design of decentralized controller for dynamic networks. The objective is to investigate the design for three application areas, virus spreading control, air traffic flow management, and communication-agent algorithm
Designing Decentralized Controllers for Dynamical Networks
PI is continuing his research in model theory, which is a branch of mathematical logic. The bulk of his research is organized around the theme of obtaining better structure theorems in three distinct settings. He will continue his investigatio
Integrated Actuation, Alignment, and Latching for Reconfigurable  Assembled 3D MEMS    Principal Investigators  Carol Livermore and George Barbastathis    'This award is funded under the American Recovery and Reinvestment Act of 2009 (Public La
Integrated Actuation, Alignment, and Latching for Assembled 3D MEMS
The PI intends to work on three different topics involving descriptive set theory and its applications in Banach space theory and topological dynamics. Firstly, he intends to further elaborate on the structure theory of large Polish group and,
Applications Of Descriptive Set Theory To Functional Analysis And Topological Dynamics
Adaptive, Reconfigurable, self-healing Soler Arrays
In this project the PI will investigate the combinatorics associated with some useful polynomials in several variables which were introduced by I. G. Macdonald in 1988, and play a central role in algebraic combinatorics, with applications to a
THE COMBINATORICS OF MACDONALD POLYNOMIALS AND RELATED OBJECTS
This project will address several fundamental questions in non-commutative algebra and field theory, specifically focusing on the brauer group.  In this project the PI studies the following question.  Given a specific field, what kinds of divis
The proposed project concerns perturbation theory of almost periodic Jacobi and CMV matrices with finite or infinite gap spectrum as well as asymptotic analysis of the associated orthogonal polynomials on the real line and the unit circle, resp
Perturbation theory for almost periodic Jacobi matrices with applications to orthogonal polynomials
Coherent nonlinear laser microscopy (CNLM) such as third harmonic (THG) and second harmonic (SHG) generation microscopes are widely used imaging tools. However, their application to date has eluded systems requiring rapid image acquisition. We
High-speed three dimensional coherent nonlinear imaging with temporal-focus depth scanned holography
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).Zhang 0901987University of WashingtonSignificant seasonal changes in arctic sea ice have been observed in recent years, characterized by unpreceden
Collaborative Research:  Changing Seasonality of the Arctic: Alteration of Production Cycles and Trophic Linkages in Response to Changes in Sea Ice and Upper Ocean Physics
ARRA Supplemental Funding for the Child Care and Development Fund (CCDF); Provide child care financial assistance to low income working families and fund activities to improve quality of child care.
HUMAN SERVICES, MISSISSIPPI DEPARTMENT OF
Community Services Block Grant Stimulus; American Recovery and Reinvestment Act of 2009.  The Mississippi Department of Human Services (MDHS) is the state agency designated to administer the CSBG program.  The state will carry out the goals, ob
I-90/Yakima River to W Ellensburg - Paving
This grant improves our understanding of the hydrologic variability associated with the Asian Monsoon system in response to precessional forcing. The work generates quantitative paleorainfall reconstructions from sediments collected from the Ch
Quantitative paleorainfall reconstruction from the Chinese Loess Plateau using 10Be and magnetic susceptibility
This grant supports research on late Pleistocene and Holocene convective and hydrologic variability in Indonesia through the recovery and analysis of new sediment cores from two large lakes on the island of Sulawesi. This research builds upon s
Collaborative Research: Reconstructing millennial-scale trends and variability in western Pacific convection and hydrology from large lakes on Sulawesi, Central Indonesia
Funding is provided to investigate whether landscape and vegetation feedbacks played a role in creating the severity and persistence of Medieval megadroughts and if these feedbacks might also impact future anthropogenic-induced aridification. S
P2C2: North American Megadrought: Atmosphere-Ocean Forcing and Landscape Response from the Medieval Period to the Near-Term Greenhouse Future
Mainstream computing - on the desktop, in the datacenter, and in embedded devices - is undergoing an unprecedented shift toward parallelism as manufacturers adopt multi-core architectures. Conventional multi-core processors have very inefficien
MCDA: Efficient Mechanisms for Multicore Processors
The foreseeable future research of the PI will concentrate on differential topology questions and on also mathematical physics. What follows lists six specific topics of concentration: - Using the Seiberg-Witten equations to study the dynamics
This Integrative Graduate Education and Research Traineeship (IGERT) award supports the development of a multidisciplinary graduate training program of education and research in food systems as they relate to poverty reduction. Most people suff
IGERT: FOOD SYSTEM FOR POVERTY REDUCTION
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). Managing reactive nitrogen is one of the great scientific and social challenges of the 21st century. Translating technical understanding to public
IGERT: Nitrogen Systems: Policy-oriented Integrated Research & Education (NSPIRE)
Public software and an appropriate user-friendly interface will be developed and released for performing accurate quantum mechanical calculations of fundamental three-body processes. This new computational tool will permit scientists from many
Universal Quantum Few-Body Codes for Research and Education
Collaborative Research: Understanding Whole-genome Evolution through Petascale Simulation Proposal Summary Because of the advent of high-throughput sequencing and the consequent reduction in cost of sequencing, we are seeing an explosion in the
Collaborative Research: Understanding Whole-genome Evolution through Petascale Simulation
In this project the PIs will investigate human-robot interaction in situations where a human is highly dependent upon a robot that serves as the medium for the outside world, such as emergency response, hostage negotiation, and healthcare. In t
HCC: Medium: Collaborative Research: The Social Medium is the Message
Reliable weather and climate prediction at local-to-global scales ultimately depends on a full and quantitatively accurate understanding of microphysical processes governing interactions of individual cloud droplets and their interplay with clo
Collaborative Research: PetaApps: Enabling Multiscale Modeling of Turbulent Clouds on Petascale Computers
This project is defining the basis for lower-complexity robotic hands that can grasp a wide variety of objects in noisy and unstructured environments. The new generation of mobile and humanoid robots still lacks basic ?hands? that can reliably
RI: Medium: Collaborative Research: Robotic Hands: Understanding and Implementing Adaptive Grasping
RI: Medium: Collaborative Research: Robotic Hands:  Understanding & Implementing Adaptive Grasping
This project is focused on implementing novel methods for uncertainty quantification in the context of modeling carbon sequestration. Significant advances in both the basic methodology and computational implementation are proposed. Advances in
Collaborative Research: Uncertainty Quantification For Petascale Simulation Of Carbon Sequestration Through Fast Ultra-scalable Stochastic Finite Element Methods
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).   This project is centered around the study of complex version of the very famous Ricci flow, Kahler-Ricci flow. Many closely related objects, for
ahler-Ricci Flow with Degenerate Cohomology Limit
A significant majority of current Internet traffic is due to distributing content, yet the Internet was designed to be largely agnostic to characteristics of the content flowing over it. This research investigates the design and operation of a
NeTS: Medium: Collaborative Research: Designing a Content-Aware Internet Ecosystem
TECHNICAL SUMMARY This award supports theoretical research and education in systems far from equilibrium that evolve with slow dynamics. The PI aims to generalize a theoretical framework that he has proposed to systems that evolve according to
Relaxation and Aging Processes out of Equilibrium
Our nation's infrastructure relies increasingly on networks that connect growing amounts of data and systems, including those that interact directly with the physical world. Increased connectivity leads to a higher degree of vulnerability to at
NetSE: Medium: A Data Mining Approach to Diagnostic Debugging in Sensor Networks
This a joint grant with two researchers at UT Austin, the purpose of which is to develop the tools and abstractions necessary for building concurrent systems that are secure because critical operations are done atomically.  Concurrency bugs, wh
TC: Medium: Collaborative Research: Securing Concurrency in Modern Systems
The overall purpose of this award is to develop probabilistic graphical models for integrating mixed-mode data.  The work is motivated by challenges in emerging application areas such as epidemiological simulation, geoscience modeling, and stud
III: Medium: Collaborative Research: Intergration, Prediction, and Generation of Mixed Mode Information using Graphical Models, with Applications to Protein-Protein Interactions
TECHNICAL SUMMARY:  The ability to control functional group placement and polymer backbone structure in synthetic polymers is important for understanding fundamental structure property relationships as well as designing polymeric materials with
Precisely Functionalized Alternating Copolymers Based on Substituted Stilbene Monomers
Wireless mesh networks promise a flexible and cost-effective solution for bringing high-bandwidth low-latency applications to the home. Two orthogonal but immensely attractive approaches for designing high-performance mesh networks are network
NeTS: Medium:Collaborative Research: Unifying Network Coding and Cross-Layer Optimization for Wireless Mesh Networks: From Theory to Distributed Algorithms to Implementation
Despite years of effort, the underlying structure of the Internet is still largely opaque to networking researchers. This opaque structure is also a barrier to ISP administrators trying to diagnose connectivity problems - when a problem occurs,
NeTS:Medium:Internet Measurement in the Large
'This project determines the fundamental limits of network secrecy from a network coding perspective, and then applies this theory to improve security guarantees in peer-to-peer and wireless networks. As network coding gains prominence as an i
NeTS: Medium: Collaborative Research: Secure Networking Using Network Coding
This proposal consists of several projects investigating the new area of research known as 'String Topology', as well as related questions. String topology, a theory that was first introduced  in 1999, studies structures on spaces of paths, loo
String Topology, Field Theories, and the Topology of Moduli Spaces
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). Technical: The objective of this project is to study and understand fundamental phenomena underlying the interaction between the piezoelectric pot
ARRA Coupling between piezoelectricity and charge transport property in ZnO nanowires
Ambulatory Surgical Center (ASC) - Healthcare-Associated Infection Prevention Initiative  --  State Plan.  This initiative will significantly expand the awareness of proper infection control technique among ASC's and SA's, increase the extent t
Ambulatory Surgery Center Healthcare Associate Infection Prevention Initiative
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  TECHNICAL SUMMARY:  This collaborative project aims to study the detailed interfacial structure of semiconducting and dielectric polymers. The in
Collaborative Research: Characterization of the Microstructure and Charge Transport at Interfaces of Semiconducting Polymers
Quantile regression (Koenker and Bassett, 1978) has emerged as an important statistical methodology, and has been used in a wide range of applications including economics, biology, ecology and finance. Very often a data set is not perfectly obt
Quantile Regression with Mismeasured or Missing Covariates
The proposed project aims to develop new statistical theory and methodology for high-dimensional structured data. The project is inspired by challenging problems that arise in two important biological applications: disease gene identification a
Markov Chain Monte Carlo (MCMC) is a flexible computational technique that has proven very useful to many scientific disciplines and is the backbone of current implementations of Bayesian inference. Recent research developments suggest that the
Adaptive Markov Chain Monte Carlo methods
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). This is a research project that involves theoretical and computational studies of the electron dynamics in metal and semiconductor nanostructures.
RUI: Spectroscopy of Many-Body Processes in Nanostructures
In the context of missing data and semiparametric regression models (i.e., models with both finite dimensional and infinite-dimensional parameters), little work has been done on efficient estimation and still less on estimating general function
EFFICIENT ESTIMATION IN SEMIPARAMETRIC REGRESSION WITHPOSSIBLY INCOMPLETE DATA.
To meet the rising need for analyzing functional data with complex structures, the investigators develop innovative statistical methods under three broad categories: (1) Multi-level functional data analysis. New methods for multi-level principa
STATISTICAL METHODS FOR COMPLEX FUNCTIONAL DATA
This collaborative project will investigate the physics of electronic mesoscopic structures. These structures are made of a large number of atoms, but are sufficiently small to exhibit quantum phenomena that are not found in macroscopic objects
Collaborative Research: Coherent Transport in the One-Dimensional Limit
Stellar opacity is the fundamental quantity in stellar models. In recent years an inexplicable solar abundances anomaly has emerged, between light element abundances derived spectroscopically and from the most sophisticated atmospheres models,
(ARRA) A re-examination of stellar opacities and implications for solar models
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). The Inorganic, Bioinorganic, and Organometallic Chemistry Program supports the efforts of Professor Jon A. Zubieta of Syracuse University for the
Solid State Coordination Chemistry of Organic/Inorganic Hybrid Materials
Under this award, Drs. Jinyoung Kim (University of Arizona) and William Sherry (National Solar Observatory) will carry out a comprehensive observational study of two star forming regions (the W3 and W4 H II regions) that are representative of a
Triggered Star Forming Regions: Cradles of Forming Solar Systems?
Rapid changes in the arctic climate system that occurred in the relatively recent past can be compared with the output of climate models to improve the understanding of the processes responsible for nonlinear system change. This study focuses o
Collaborative Research: Nonlinearities in the Arctic Climate System During the Holocene
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).    The coming years will see the emergence of location-aware applications with sub-meter accuracy and minimal infrastructure requirements, operati
Cooperative Tracking in Harsh Environments: Statistical Framework and Network Experimentation
The investigator's research areas are number theory and representation theory. In particular, the investigator studies p-adic Galois representations and p-adic Hodge theory, with an eye towards applications to the modularity of Galois represent
This is a project to investigate aspects of low-dimensional dynamical systems. The proposed research addresses the connection between algebraic properties of a group that acts on a surface in an area-preserving way and the possible topological
The objective of this research is to improve the reliability and restoration capability of wide area Power Grids (PG) thereby reducing power outages and their cascade effects. The approach is to embed novel intelligent sensors with distributed
Creating the Next Generation Power Grid with Massively Distributed Intelligent Sensors
The objective of this research is to demonstrate energy efficient, mixed-signal silicon transceiver circuitry using time-domain signal modulation for high-speed serial links. The approach is to employ plesiochronous double-edge pulse-width modu
Plesiochronous Communication for Silicon-Constrained High-Speed Serial Links
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). This award will support a study that addresses the hypothesis that the expanding extent and duration of seasonal open water in the Arctic has the
Collaborative Research:  Impacts of the Changing Seasonality of Wind-driven Mixing on the Arctic System
The research focuses on the mathematical analysis of the evolutionary solutions to the equations from gas dynamics and fluid flow. In gas dynamics the goal is to gain a deeper understanding of relativistic kinetic equations coupled with their i
The theory of graph packing provides a general framework for organizing many areas of graph theory. Two famous results that can be phrased in this language are Dirac's Theorem on the existence of Hamiltonian cycles and the Hajnal-Szemerédi The
This project aims to further our understanding of higher-dimensional shifts of finite type (SFTs) and cellular automata (CA). Broadly speaking, the goal is to describe their dynamics and identify types of dynamics that cannot occur in them. In
Dynamics of multidimensional symbolic systems
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). The research activities supported by this grant include the following aspects of the geometric theory for the Monge-Ampere equation: a regularity
The Monge-Ampere Operator in Analysis and PDEs
The objective of this research is to design and construct a self-aligned tunnel logic device will consume less power in the off-state and require less switching power for device turn-on. The approach will be to use simulations to determine the
GOALI: 3D III-V Green transistors with ultra-steep subtreshold slope
The PIs will study higher secant varieties of classically studied varieties such as Segre varieties, Grassmann varieties, and Segre-Veronese varieties. These varieties correspond to parameter spaces for rank one tensors, alternating tensors, an
Collaborative Research: Algebraic Geometry of Tensor Parameter Spaces
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). Changes in the magnitude and seasonality of Arctic summer vegetation production over the past several decades have been documented. These changes
Collaborative Research: Investigating the relationships between changing seasonality of marine shelf ice/ocean conditions and tundra vegetation, and their effects on energy and carbon budgets
The primary goal of this project is to investigate the mechanisms underlying the seasonal response of the climate system to Arctic sea ice loss within the context of anthropogenic climate change. This research will utilize the NCAR Community Cl
Collaborative Research: The Seasonal Response of the Arctic and Global Climate System to Projected Sea Ice Loss within the Context of GHG-induced Climate Change
I-90/Lake Easton to Big Creek Br EB - Concrete
SR 902/Medical Lake to I-90 - Rumble Strips - Centerline
Funding is provided to further test the early anthropogenic hypothesis (EAH) that agriculture produced greenhouse-gas emissions large enough to reverse natural downward trends in carbon dioxide and methane concentrations several thousand years
ARRA Collaborative Research: Exploring the Early Anthropogenic Hypothesis
Intellectual Merit: This grant will support the development of calibrated, highly-resolved, and absolute-dated stable isotopic and trace-metal time series from multiple speleothems preserved in multiple cave systems along a N-S transect from Ea
COLLABORATIVE RESEARCH: Global Change and the Terrestrial Paleoclimate Record from Eastern North America: 600,000 years BP to Present
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  This study will quantitatively reconstruct deep ocean carbonate chemistry changes across the Paleocene-Eocene thermal maximum to determine the de
Collaborative Research; Reconstructing Deep-sea Acidification During the Paleocene-eocene Thermal Maximum
The PI will investigate several aspects of polynomial mappings and related matters. One topic involves orbits of complex polynomials. The proposer will study when the cartesian product of finitely many such orbits has infinitely many points in
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). This project will create and support an open source computer code for entangled quantum many-body dynamics called Time-Evolving Block Decimation (
Time Evolving Block Decimation: Entangled Quantum Dynamics with Ultracold Molecules
We will develop a model to explain how magnetic energy is rapidly released in various natural plasmas such as the Earth's magnetosphere(Northern lights) or the Sun's corona(solar flares).
Energetic Consequences of Fast Magnetic Reconnection
This collaborative investigation into the forest atmosphere photochemistry will apply a unique set of collaborative approaches, focused on the chemistry occurring in the near-canopy environment. It is now well known that forests emit biogenic v
Collaborative Research: Program for Research on Oxidants: Photochemistry Emissions and Transport (PROPHET) 2009--Community Atmosphere-Biosphere Interactions Experiment (CABINEX)
This project addresses the question of the nature of dark matter in the Universe with an experimental search for Weakly Interactive Massive Particles (WIMPs) using two-phase xenon detectors. This group is currently operating at the 100 kg mass
Collaborative Proposal:  Continuation of the XENON Dark matter Project: Construction and Underground Operation of an Upgraded XENON100 Detector
New and exciting technologies have created opportunities for developing rich open-ended learning environments that combine a number of different learning paradigms and resources. Students can complete quests in game environments, engage in inqu
HCC: Medium: Collaborative Research: Formal Analysis of Choice-Adaptive IntelligentLearning Environments (FACILE) that support Future Learning
Force-feedback, or haptic, applications in medicine, engineering, and design are increasing in popularity and importance based on the advantages of haptic devices in providing intuitive and realistic interactions with virtual environments. Howe
HCC:Medium: Collaborative Research: Hand-Mounted Tactile Display for Haptically Identifying Shape and Dexterous Manipulation
The investigator will construct different statistical models for the general Internet traffic and traffic from one extremely time-sensitive application, Voice over Internet Protocol (VoIP), due to the different traffic generation mechanism: A V
Statistical Models of Internet Traffic and Queueing Analysis
The goal of this research project is to investigate a number of topics in the intersection of geometry, the analysis of nonlinear partial differential equations (PDE's) and general relativity (GR). These topics share a common theme: to investig
Geometry and PDE Analysis in General Relativity
The goal of our interdisciplinary effort between computational scientists, physicists, engineers and applied mathematicians is to build an all scales unified simulation system that can exploit the next generation of petascale systems and beyond
Collaborative Research: A multiscale unified simulation environment for geoscientific applications
Traffic measurement is central to network operation, management, and security. Yet, support for measurement was not an integral part of the original Internet architecture. This project aims to develop a programmable measurement architecture tha
NeTS: Medium: Collaborative Research: Towards Versatile and Programmable Measurement Architecture for Future Networks
The spread of contagions such as opinions, attitudes, beliefs, and diseases across a national population is a well-known complex problem; the recent fear of avian flu epidemics and financial contagion serve as excellent examples. Other examples
Collaborative Research: Coupled Models of Diffusion and Individual Behavior Over Extremely Large Social Networks
Wireless sensor networks (WSNs) are becoming pervasive in both civilian and military domains. Low cost and ease of deployment of these networks necessitate the use of batteries as the primary source of power. As a result, battery capacity has e
NeTS:Medium:Collaborative Research: Exploiting Battery-Supply Nonlinearities in Optimal Resource Management and Protocol Design for Wireless Sensor Networks
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  The project proposes the computational modeling of hazards related to explosives by combined means of modeling, algorithmic and computer science
The proposer intends to study universal equations and other properties of Gromov-Witten invariants of compact symplectic manifolds. Gromov-Witten invariants are defined by the intersection theory on moduli spaces of stable pseudo-holomorphic ma
Gromov-Witten invariants and integrable systems
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).Significant progress has been made on technical solutions for implementing security while preserving varying degrees of privacy for mobile electron
TC:Medium:Collaborative Research: Mobile Personal Privacy and Security - A New Framework and Technology to Account for Human Values
There is a growing need for wireless networks that can sustain high data rates, are robust to interference, make efficient use of battery resources, and offer secure communications. This project introduces cooperative beamforming (CB), a novel
NeTS: Medium: Collaborative Research: Cooperative Beamforming for Efficient and Secure Wireless Communication
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).   Accurate wireless measurements are critical to the sustained growth of deployed wireless networks, as well as the successful development of wire
NeTS: Medium: AirLab: Distributed Infrastructure for Wireless Measurements
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). Mitchell's project is an investigation of affine flag varieties from the point of view of topology, combinatorics, Lie theory and algebraic geomet
Schubert and Birkhoff varieties in affine flag varieties
Statistical design and analysis of experiments is an effective and commonly used tool in scientific discoveries. The rapid growth in technology and computing power has made available many complex experiments, such as those with branching factor
Design and Analysis of Complex Experiments: Branching Factors and Functional Respones
The projects in this proposal are clustered around themes in low-dimensional topology, asymptotic geometry, and the dynamics of group actions. Teichmuller space and the mapping class group are objects for special attention, and tools developed
The area of research of the present proposal is low dimensional topology. The problems discussed in this proposal find origin in the study of the connections between three-dimensional topology and symplectic topology of certain families of four
Topology of 3-manifolds and symplectic 4-manifolds
The supported research will build on earlier discoveries concerning the stereospecific reagent controlled homologation (StReCH) of boronic ester derivatives by enantioenriched main group chiral carbenoids. StReCH enables a programmable iterativ
Oxygenated Carbenoids for Stereospecific Reagent Controlled Homologation
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  Recently, many genomic studies have shown that significant chromosomal spatial correlation exists in gene expression of many organisms.  Ignoring
Bayesian Hierarchical Methods for Modeling Chromosomal Spatial Correlation
INTELLECTUAL MERIT: The chemical composition of bioactive silicate bioceramics or glasses  the leached SiCa concentrations strongly influence the complex process of osteointegration by affecting the texture of the amorphous silicacarbonated hyd
ARRA Silicate Bioceramic Structure Control on Mesenchymal Stem Cell Proliferation and Differentiation
Funds are provided to explore the overarching hypothesis that relatively small-scale aspects of the response of the ice-ocean boundary layer impact polar climate
Arctic Ice-Ocean Interaction in a Time of Rapid Change
The methods for production of most ceramic materials depend on a small amount of chemical additions that distribute non-uniformly within the material; these small amounts can dominate a ceramic?s utility. These chemicals often produce additiona
Collaborative Research: Development of an Additive Selection Criteria Based on Interface Complexions
TECHNICAL SUMMARY: This proposal will examine the effect of polymer microstructure, solvent additives and solution components on lower critical solution temperature (LCST) phenomena both in solution and at surfaces. The studies proposed will us
SOLVATION STUDIES OF RESPONSIVE POLYMERS IN SOLUTION AND AT SURFACES
The investigator will develop designs for statistical experiments that adapt over time to incoming data -- so-called 'adaptive designs' -- and plans for analyzing data coming out of such experiments for two general classes of problems: (I) opti
The band gap energy range of the InGaN alloys system uniquely covers the optical solar spectral emission window at earth. InGaN could be immediately employed for realization of a new generation of so elegantly less complex to manufacture, cost-
Effects of Polarization Fields and Surface Charge Layers on p-Type Conductivity in In(Ga)N
This Focused Research Group (FRG) project explores energy applications of group-IV (Si, Ge) semiconductor materials incorporating Sn. The combination of Sn with Si and Ge may allow desirable structural and electronic properties with advantageou
Sn-Containing Group-IV Semiconductors for Energy Applications in Photovoltaics and Thermoelectricity
Dr. Gnedin will study how the intergalactic gas becomes ionized by hot stars in newly-formed galaxies, and by their active nuclei. He and his team will use very large simulations to calculate the expected absorption-line spectra from neutral hy
TOWARD UNDERSTANDING THE HIGH REDSHIFT LYMAN-ALPHA FOREST
The primary goal of this research is to constrain how magma accumulates in the continental crust and erupts at the surface in areas of active intrusion and volcanism. In particular, we are investigating preliminary evidence for active mid-crust
Collaborative Research:Investigating the Relationship Between Pluton Growth and Volcanism at Two Active Intrusions in the Central Andes
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). Dr. Willman, Dr Geha and their team will apply their well-tested algorithms to search for nearby ultra-faint dwarf galaxies in vast regions around
Collaborative Research: Searching for Ultra-Faint Galaxies Around the Milky Way
Intellectual merit. This proposal centers on control theory of partial differential equations (PDEs). While offering mathematically varied and challenging directions of research, the field of control is primarily application-driven, with an imp
Stabilization and Control in Nonlinear Structural-Acoustics, Magnetic Imaging, and Elasticity
Intellectual Merit: 'Amorphous' silicate spectral features have been observed in our solar system, young stellar objects, star formation regions, novae, diffuse and dense interstellar medium, and in extragalactic quasars and AGN. Dust contribut
COLLABORATIVE RESEARCH: AN INTEGRATED EXPERIMENTAL AND OBSERVATIONAL STUDY OF COSMIC SILICATE ASTROM
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  Dr Valluri will study stellar motions in galaxies that are triaxial or have barred disks, and harbor supermassive black holes at their centers. M
The dynamics of rotating triaxial galaxies with massive black holes
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). Dr. Willman and her collaborators will study numerical simulations that follow the formation and evolution of the Milky Way's stellar halo. They w
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  The optimal wealth process corresponding to the expected logarithmic utility maximization problem is probably the most popular and important inve
The Numeraire in Stochastic Finance Theory
This project carries out mathematical and numerical studies of potential flows of viscous and viscoelastic fluids. The Helmholtz decomposition divides the velocity into a rotational part and an irrotational part. In general, the rotational and
Dr Gebhardt and his team will use a fiber-fed spectrograph at the McDonald 2.7-meter telescope to measure stellar motions in the outer parts of nearby elliptical galaxies. The large fibers will gather diffuse light over a 2-arcminute field of v
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  Drs. Peter Bodenheimer and Douglas Lin (University of California - Santa Cruz) will undertake a study to determine the frequency of habitable pla
Population Synthesis of Hot Jupiters and Close-in Super Earths
'Dr. Andrew F. Boden of the California Institute of Technology will undertake a study of the properties of binary stars at various stages of their lives. Binary stars are fundamental calibrators of stellar evolution, since the masses of the st
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).     This research project involves a comprehensive study of galactic foreground emission for removal from sensitive maps of the Cosmic Microwave B
Modeling foregrounds for CMB and 21 cm cosmology
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). This Materials World Network project is supported by DMR-CER and DMR-OSP.  This Materials World Network research program between Prof. Roberto For
Materials World Network: Growth and Characterization of Bulk Crystals and Epitaxial Films of Beta-Ga203, SnO2, In203 and ZnO
Our knowledge of how crustal magma chambers evolve and how these magma chambers relate to plutons and eruptions is inadequate, largely because nobody has yet conducted a comprehensive study of an active crustal magma chamber. This project provi
Collaborative Research: Investigating the Relationship Between Pluton Growth and Volcanism at Two Active Intrusions in the Central Andes
REGENTS OF THE UNIVERSITY OF COLORADO, THE
Collaborative Research:  Nonlinearities in the Arctic Climate System during the Holocene
The award will support an investigation of snow accumulation in the south-eastern sector of the Greenland ice sheet. Snow accumulation rates on the Greenland ice sheet have been significantly underestimated and the missing mass prevents accurat
(ARRA) Collaborative research: Greenland ice sheet snow accumulation variability: Filling knowledge and data voids
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  The award will support an investigation of snow accumulation in the south-eastern sector of the Greenland ice sheet. Snow accumulation rates on t
COLLABORATIVE RESEARCH: GREENLAND ICE SHEET SNOW ACCUMULATION VARIABILITY: FILLING KNOWLEDGE AND DATA VOIDS
Collaborative Research: Nonlinearities in the Arctic climate system during the Holocene
Of the planet's ecosystems the Arctic is the most sensitive to climate change. Recent increases in the rate of environmental change in the Arctic pose considerable challenges to the survival of culturally and economically important, arctic-adap
Collaborative research: Understanding the role of environmental change on the long-term population dynamics of one surviving and two extinct arctic mammals
This award is funded under the American Recovery and Reinvestement Act of 2009 (Public Law 111-5).Luminescence dating has become an increasingly useful chronological tool over the last couple of decades in archaeological and geological sciences
Extending applications and improving methods for luminescence dating of archaeological materials
Funds are provided to determine how arctic zooplankton communities have varied over interannual to decadal periods, from regional to panarctic scales. The PI states the specific hypotheses that zooplankton biomass may be increasing, due to envi
Environmental change in the Arctic Ocean: a synthesis and retrospective analysis of zooplankton communities
HUMAN SERVICES, NEW MEXICO DEPARTMENT OF
The Emergency Food Assistance Program (Administrative Costs)is used to assist six member food banks with the cost of storing and distributing food.  These food banks distribute food to 600 agencies in all New Mexico counties.
The Emergency Food Assistance Program Admin
Unds are provided to investigate the microbial controls on the productivity of a coastal Arctic ecosystem by focusing on the competition between autotrophs and heterotrophs for nitrogen (N). In the winter and summer waters near Barrow, Alaska,
Collaborative Research: Does Competition for Nitrogen Between Autorophs and Heterotrophs Control Carbon Fluxes in the Westeran Coastal Arctic?
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).    The main objective of our research is to improve our understanding of the structure and deformation of Earth?s crust and lithospheric mantle be
Structure and Deformation of the Crust and Upper Mantle Beneath SE Tibet
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).    This project is co-supported by the Petrology & Geochemistry and Tectonics programs of the Division of Earth Sciences, and sponsored also by th
The Dynamics of Mantle-Melt Extractions Systems: A field and Theoretical Approach
(a) Non-technical explanation of the project's broader significance and importance: Small amounts of melt that form deep beneath Earth?s surface rise slowly to feed volcanoes such as those observed in Iceland and Hawaii. As this melt moves upwa
Effect of a Small Amount of Melt on Diffusion and Deformation in Earth's Mantle
Volcanoes create hazards for millions of people worldwide, including many living in parts of the USA. Scientists can now forecast the timing of many eruptions at well-monitored volcanoes. Unfortunately, it is currently not possible to accuratel
Estimating Eruption Model Input Parameters From Direct Observations of Deeply Eroded Basalt Conduits, San Rafael, UT
We will develop physically-based models of magma chambers and conduits that are coupled to the elastic surroundings.  As magma ascends the decrease in pressure results in volatile exsolution.  This decreases magma density, but increases viscosi
Modeling recent behavior of Mt. St. Helens: extrusion dynamics, deformation, and seismicity
Shallow tectonic earthquakes are driven by instabilities that take place in crustal faults. Earthquake may be thought of as a dynamically running shear crack. Friction and wear at the crack surface determine the stability of the faulted region.
ARRA Friction and aging of silica: atomistic simulations for fundamental understanding of earthquake mechanics
The burgeoning revolution in high-end computer architecture has far reaching implications for the software infrastructure of tools for performance measurement, modeling, and optimization, which has been indispensable to improved productivity in
CSR: Large: Collaborative Research: Multi-core Applications Modeling Infrastructure (MAMI)
'The burgeoning revolution in high-end computer architecture has far reaching implications for the software infrastructure of tools for performance measurement, modeling, and optimization, which has been indispensable to improved productivity i
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5)'.  This project will investigate why many small molecules self-assemble in dilute solution to form very long '1-dimensional' (1D) objects, thinner
How Molecules Self-Assemble into 1 Dimensional Structure
The Analytical and Surface Chemistry (ASC) program supports the research project of Prof. Andrew Bocarsly of the Department of Chemistry at Princeton University. Prof. Bocarsly and his students will study the mechanism of electrochemical reduct
A Study of Charge Transfer Processes in the Catalyzed Conversion of Carbon Dioxide to Methanol and Higher Order Alcohols
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). In this RUI project funded by the Inorganic, Bioinorganic, and Organometallic Chemistry Program of the Chemistry Division and the Solid State and
RUI: Synthesis of organically templated gallium sulfites
The Analytical and Surface Chemistry (ASC) program of the Division of Chemistry supports the research program of Professor Richard P. Van Duyne at Northwestern University. Professor Van Duyne and his coworkers are developing new concepts and ex
Molecular Plasmonics: Single Molecules, Single Nanoparticles and Scanning Probe Microscopy
The Inorganic, Bioinorganic and Organometallic Chemistry Program supports the research of Professor Janet Bluemel of Texas A&M University to synthesize a new generation of linkers for the immobilization of catalysts on oxide supports. New 4,4'-
RIGID BIPHENYL AND TETRAPHENYL-ELEMENT LINKER SCAFFOLDS FOR SUPERIOR IMMOBILIZED CATALYSTS
The great 15 November 2006 Mw=8.3 and 13 January 2007 Mw=8.1 Kuril earthquakes rup-tured one of the most conspicuous gaps in subduction-zone seismic activity, a 600-km long Ku-ril arc segment that had not experienced a single great earthquake f
Collaborative Research: Postseismic deformation of the Earth after the great 2006-2007 Kuril earthquake doublet: Implications for Mantle rheology
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  This Small Business Innovation Research (SBIR) Phase I project will develop a new type of optical power monitor based on microwires and nanowires
SBIR Phase I: Optical Detectors Based on Transparent Microwires and Nanowires on Plastic Film
Pike County Welcome Center Site Improvements - I-59
Maalo Road Resurfacing, Mile Post 0.0 to Mile Post 1.0
This award provides for ARRA Cost of Living Adjustment (COLA) and Quality Improvement funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for BCMW Head Start program.  Head Start promotes the school readiness of lo
COLA awards provide cost of living increase for Head Start Early/ Head Start staff and notable service and support items affected and verified by the inflationary index.  The QI (Quality Improvement) awards are designated no less than 50% profe
ARRA Cost of Living Adjustment (COLA, and Quality Improvement Funding consistent with the provisions of section 640(a)(5)of the Head Start Act.
ECONOMIC OPPORTUNITY PLANNING ASSOCIATION OF GREATER TOLEDO,
ARRA COLA and Quality Funds will be used to: - Hire two full time Family Service Workers (FSW's). - Improve program accessibility and safety. - Provide professional development for teaching staff to improve staff qualifications. - Increase the
ALLEGAN COUNTY RESOURCE DEVELOPMENT COMMITTEE INC
This award provides for ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start program.
This award provides for ARRA Supplemental Funding for COLA and Quality Improvement funding consistent with the provisions of the Head Start Act. Head Start promotes school readiness for low income children.
Fayette County IN School Corporation Head Start
LORAIN COUNTY COMMUNITY ACTION AGENCY, INC.
LCCAA was awarded a total of $512,471 of ARRA funds in two categories.   A total of $117,839 was awarded as a temporary COLA (hourly wage) increase of 1.84%, with $109,884 for Head Start and $7,995 for Early Head Start.  Monies also supported w
Head Start:  Full year part day handicapped training & technical assistance:  This award provides for ARRA Cost of Living Adjustment(COLA) and Quality Improvement funding consistent with the provisions of Section 640(a)(5) of the Head Start Act
Kokomo-Center School?s Head Start Program?s COLA award funded wage increases and fringe benefits, helped absorb higher operating costs, which included the cost of consumable supplies. Funds were also used for the adult and child food budget, pr
ARRA funding for the Cost of Living Allowance totals $119,264. The Agency expects to incur higher health insurance costs for Head Start and Early Head Start staff and plans to use ARRA funds to offset these costs. Health insurance co-pays will
PRAIRIE FIVE COMMUNITY ACTION COUNCIL, INCORPORATED
Discretionary Grant - Head Start:  Full year, part day, handicapped, training and technical assistance.
This ARRA Early Head Start project serves 96 children in Hocking, Athens and Perry Counties in Ohio.  Using the Early Head Start home based model, funds are used to provide weekly home visits to parents with children from birth to three years o
This award provides ARRA Cost of Living Adjustment (COLA) and Quality Improvement FJunding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start program.  Head Start promotes the school readiness of low-in
Head Start: Full Year Part Day  Handicapped Training & Technical Assistance
This award provides for ARRA Cost of Living Adjustment and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start Program.  Head Start promotes the school readiness of low-income
Head Start - staff traiing in Woven Word (Dialogic Reading)and Bridges Out of Poverty (understanding families); playground improvement; upgrades to busses; child-staff ratios, tuition reimbursement and Literacy Consultant.
This award provides for ARRA Cost of Living Adjustment (COLA) and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for Head Start program.  Head Start promotes the school readiness of low-inc
COMMUNITY ACTION PROGRAM INC OF WESTERN INDIANA
All project activities have been started.  The Behavioral Health Specialist has started training the staff and providing mentoring to classroom staff responsible for working with children.  Two education managers completed one week of Conscious
CATHOLIC CHARITIES OF MONROE COUNTY, INC.
ARRA COLA and quality improvement funding consistent with the provisions of section 640(a)(5) of the head start act.  Head Start promotes the school readiness of low-income children through the provision of comprehensive health, developmental a
The award will allow the project to retain a Family Service Aide to work with families oroviding resources, transportation and other supports.  The award will also allow professional development for program staff as well as transportation for f
This award provides for ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for  the Head Start and Early Head Start Program.  Head Start promotes the
Head Start promotes school readiness of low-income children through provision of comprehensive health,developmental & family services.Permanent COLA $91,148 (3.06%)  ARRA COLA $46,805 (1.84%): Eligible Head Start staff will receive a cost of li
TRI-COUNTY COUNCIL FOR CHILD DEVELOPMENT, INC.
1. ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act. 2. Children Served ? 958. 3. Hired new family advocate and staffed a full day classroom of 20 c
This award provides for ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistant with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start and Early Head Start program.  Head Start promotes the s
Head Start ? Provide a one-time, temporary 1.84% across the board wage/salary increase for all Head Start employees.   Convert one part day, part year Head Start classroom to a full year, full working day (10 hour) classroom for children from f
Head Start:Full Year Part Day Handicapped Training and Technical Assistance
CHILD DEVELOPMENT COUNCIL OF FRANKLIN COUNTY, THE
This award allowed us to hire 15 additional staff such as teacher assistants and one health and one mental health consultant, all were hired in the 4th quarter 2009.
HEAD START:FULL YEAR PART DAY HANDICAPPED TRAINING AND TECHNICAL ASSISTANCE
This award provides for ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start Act for the Head Start and/or Early Head Start program f
Early Head Start of Carey Services Cost-of-Living and Quality Improvement Grant.  There are 122 children served by this program through the following program options: home-based, center-based and combination options.  EHS of both Grant and Blac
The Recovery Act funding included a cost of living adjustment that gave an immediate increase in wages to approximately 33 employees who work in the Early Head Start department.  The Recovery Act award also included funding for quality improvem
Early Head Start- COLA and Quality Improvement  This award provides for ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start and/or E
This award provides for ARRA Head Start Expansion funding to serve 29 children in Saginaw County.  The Head Start program provides center based services for low-income families with young children (3-5) to promote the healthy development of the
This award provides ARRA Head Start Expansion to 68 children ages 3 -5 years old in a center-based opton.  The center is based in Shelby County, Ohio.  Head Start promotes the school readiness of low-income children through the provision of com
Economic adjustment assistance for ARRA Industrial Park Expansion.  Includes water, sewer, curb, gutter, and paving.
Acquisition of a 17-acre site with parking facilities, renovation of a 71,000 sq. ft. building and construction of a 3,000 sq. ft. attached presentation/ conference building to create the Technology, Innovation and Entrepreneurship (TIE) Canter
Eda funding to be combined with IDOT funding for the resurfacing and rebuilding of both Wabash Avenue & 17th Street in Centralia & Wamac, IL
MIDWEST INTELLECTUAL PROPERTY MANAGEMENT INSTITUTE, N.P.
To fund the expanded operations of the Midwest Intellectual Property Management Institute, a division of Renew Moline, Inc., in its efforts to transfer underutilized intellectual property (patents) held by corporations to stimulate economic gro
Midwest Intellectual Property Management Institute
Bee Community Action Agency (BCAA) will utilize ARRA Quality Improvement and ARRA COLA funding to provide activities that will foster program improvements consistent with the Head Start Reauthorization Act of 2007.  Activities will include educ
Architectural Services - Engineering Drafting Services
0600804 - US Geological Survey - Tunison Lab of Aquatic Science
Architect and Engineering (A/E) Services on the design for rehabilitation of building structures. Work includes rehabilitation of electrical and life safety systems.
This award provides for ARRA cost of living adjustment and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act.
Head Start/Early Head Start: This award provides for ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start and/or Early Head Start pro
PINE BELT MULTI PURPOSE COMMUNITY ACTION AGENCY INC
THIS AWARD PROVIDES FOR ARRA COST OF LIVING ADJUSTMENT (COLA) AND QUALITY IMPROVEMENT FUNDING CONSISTENT WITH THE PROVISIONS OF SECTION 640(a)(5) OF THE HEAD START.  HEAD START PROMOTES THE SCHOOL READINESS OF LOW-INCOME CHILDREN THROUGH TH PRV
New Mexico State University, required Dona Ana County Head Start program to give pay increase to the Head Start staff equal to the pay increase that New Mexico State University gave to their staff.  Consequently, the Head Start program had to r
It is the goal of our grantee, the Iberville Parish Council, and the Head Start Policy Council to ensure that Head Start employees have the necessary wages, skills and knowledge to effectively function as skillfull advocates for the children en
WILLIAM SMITH, SR. TRI COUNTY CHILD DEVELOPMENT COUNCIL, INCORPORATED
This award provides for ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of section 640(a)(5) of the Head Start Act for the Head Start and Early Head Start programs.  Head Start and Early Hea
This grant awards funds made available to the Head Start program.This action awards a cost-of-living adjustment and quality improvement.
Cost-of-living adjustment (COLA) increase of 1.84% in the amount of $15,098 for Head Start.  Funds are obligated to pay for staff salaries over the 12-month period after staff retuned to work in the summer/fall of 2009. Quality improvement fund
The Community Services Office, Inc. Head Start employees received a Cost of Living adjustment of $23,374.  The agency improved the salaries and fringe benefits of staff, enabling the agency to attract and keep staff once employed.  In the past,
BLACK RIVER AREA DEVELOPMENT CORPORATION
This award provides for ARRA Cost of living Adjustment and quality improvement funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start and Early Head Start program.  Head Start promotes the school re
Head Start/Early Head Start Quality Improvements
HS 2009 ARRA FUNDING THE GRANT'S PURPOSE IS TO AWARD A COST-OF-LIVING ADJUSTMENT INCREASE OF 1.84% FOR 12 MONTHS FOR ALL HS STAFF MEMBERS. THE FUNDING WILL BE USED TO HIRE A FULL-TIME MARSHALLESE INTERPRETER,AN ASSISTANT EDUCATION/LITERACY SPEC
Head Start ARRA COLA To provide Head Start services to 1,185 children in multiple counties. To also provide nutrional, health, and dental services to eligible children in multiple counties.
curriculum.  Also the Mental Health Consultant was able to provide more in depth training for the staff in the Child Behavior Awareness area, which was greatly needed.  As we ended the project period we were able to fulfill all area that we an
WEST ORANGE-COVE CONSOLIDATED INDEPENDENT SCHOOL
ARRA Cost of Lving -  and additional expenses fringe benefits; quality improvements outside doors replaced; seatbelts for buses; ESL teacher certifications.
This award provides for American Recovery & Reinvestment Act(ARRA)Cost of Living Adjustment (COLA)and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start program.  Head Start
LITTLE DIXIE COMMUNITY ACTION AGENCY, INC.
ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act ARRA COLA and Quality Funds will be used to: * Hire one Family Advocate * Hire one Caregiver Aide *
Grant for Early Head Start program under the ARRA Act.  Grant amounts: COLA = $27,911. QI = $64,850.  The awards provided for a Cost of Living Adjustment and Quality Improvement Funding consistent with the provisions of Section 640(a) (5) of th
Increase the salaries and benefits of staff through a cost of living adjustment to improve the  overall quality of program.   Quality Improvement to improve playground area on a campus that moved classrooms.
Project Name: Head Start ARRA Expansion  Number of Children Served: 51 Program Option: Full-day, center based Service Area:  Area within boundaries of Lubbock ISD Head Start promotes the school readiness of low-income children through the provi
The Head Start ARRA Expansion Grant is to provide quality Head Start services to an additional 143 low income children and families in Caddo Parish. Head Start promotes the school readiness of low-income children through the provision of compre
Cost of living adjustment in the amount of 1.84% and quality improvement funds
COMMUNITY SERVICES AGENCY OF SOUTH TEXAS INC
CSA Head Start and Early Head Start project serves 0 to 4 population in the counties of Dimmit 100, La Salle 45, Frio 138, and Maverick 504.  The total amount served is 787 infants, toddlers and preschool children in a center based program.  To
GULF COAST COMMUNITY SERVICES ASSOCIATION
Gulf Coast Community Services Association (GCCSA) is funded to serve 1864 Head Start Children and 84 Early Head Start Children age infant to 5 years and pregnant women in Harris County and in the Fifth Ward area of Houston.  The American Recove
These grant funds have been used to provide a program-wide cost of living salary increase of 1.84%.  In addition a moderate salary increase was provided to Head Start program coordinators.  These employees hold Masters and other advanced degree
COMMUNITY ACTION PROGRAM FOR CENTRAL ARKANSAS
Award Description - Head Start promotes the school readiness of low-income children through the provision of comprehensive health, developmental and family services. This award was used to increase the compensation of early childhood staff thro
Cost of Living Adjustment, Quality Improvement Project for Head Start/Early Head Start program serving 332 infants/toddlers/children (ages 6 weeks to 5 years) and families.  Children and families are served in center-based care five days per we
ARRA Cost of Living Adjustment (COLA), and Quality Improvement funding consistent with the provisions of Section 640(a)(5) of the head Start Act for the Head Start program. Head Start promotes the school readiness of low-income children through
Awarding Office is OA/OGM Region VI Program .  Title is Head Start with the award authority  ARRA.  This is a Service Award with awards of a Cost of Living Adjustment and Quality Improvement funds for Head Start.  193 children to be serviced in
ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act.  This action awards a cost-of-living adjustment (COLA) increase of 1.84% in the amount of $46,597
Head Start Quality Improvement and COLA AARA funds that will allow for the provision of educational stipend and supplement group health insurance for staff as well as provide funds for training for Head Start staff, teachers and administrators
Head Start Quality Improvement and COLA AARA
Early Head Start ARRA Cost of Living Adjustment (COLA) and Quality Improvement (QI).  We expect this funding to help us retain valuable teaching staff and support staff, upgrade their knowledge base for continued model status excellence in chil
ARRA Cost of Living (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act - The Galena Park ISD (GPISD) Early Head Start program is seeking to continue the provision of child developme
Texas Tech University Early Head Start provides full day center-based care for 32 infants and toddlers and a home-based program for 24 infants, toddlers and pregnant women.  Our goal is to promote social and cognitive development in children fr
This award provides for ARRA Cost of Living(COLA) adjustment for all current employees, and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head start act for the Head Start program. Head Start promotes th
Head Start ARRA Expansion to provide Head Start services to 34 children in Jack County and provide nutritional, health, and dental services to eligible children.
Award Title:  Head Start Expansion (ARRA) Purpose: CSISD Head Start expansion classroom has four important elements that comprise its strong foundation.  These are separate in nature and in actuality, but they combine to create a whole child, w
Safety and Resurfacing from Structure 1013800 to Structure 1012700-Hollow Road
Highway Infrastructure Investment - Bridge replacement, no added capacity (no added traffic lanes) - From funding for use in any Area (flexible)
Highway N-70, Middle Loup Bridge, Arcadia Bridge
This project will establish a monitoring network in two watersheds of the Luquillo National Forest in Puerto Rico to evaluate the physical, chemical, hydrological and biological processes involved in weathering of bedrock and the evolution of t
Transformative Behavior of Energy, Water and Carbon in the Critical Zone: An Observatory to Quantify Linkages among Ecohydrology, Biogeochemistry, and Landscape Evolution We are developing an interdisciplinary observatory in the southwestern US
CZO: Transformative Behavior of Water, Energy and Carbon in the Critical Zone: An Observatory to Quantify Linkages among Ecohydrology, Biogeochemistry, and Landscape Evolution
The integrated observing systems that comprise the EarthScope Facility can be used to address fundamental questions at all scales from the active nucleation zone of earthquakes, to individual faults and volcanoes, to the deformation along the p
Collaborative Research: EarthScope Facility Operations/Maintenance (FY2008-FY2013). Two Amendments to the grant are ARRA funds Amendment 5 PBO FY08 ARRA Core Funding ($1,398,276) and Amendment 6 ARRA Cascadia PBO GPS High Data Rate Upgrade ($2,
Lake Vida is the largest lake of the McMurdo Dry Valleys, with an approximately 20 m ice cover overlaying a brine of unknown depth with at least 7 times seawater salinity and temperatures below -10 degrees C year-round. Samples of brine collect
Collaborative Research: Geochemistry and Microbiology of the Extreme Aquatic Environment in Lake Vida, East Antarctica
Using Inuit Qaujimajatuqangit, Knowledge To Guide The Development Of Hypotheses On Narwhal Tusk Function. Results from this study will uncover the knowledge recorded in the interviews of 55 hunters and elders from over 12 communities in the Hig
Using Inuit Qaujimajatuqangit, Traditional Knowledge, to Guide the Development of Hypotheses on Narwhal Tusk Function
MINT FARM INDUSTRIAL PARK PROPERTY OWNERS ASSOCIATION
This project is located in City of Longview within the Mint Farm Industrial Park. The Mint Farm Industrial Park is a public / private partnership between the City of Longview and WREDCO to develop an industrial park that creates new opportuniti
Mint Farm Industrial Park infrastructure, construct new road South Weber Ave 2500 LF long and 40 LF wide, with curb and gutter, sidewalk, storm, lighting, landscaping, sewer and water utilities. Provide access and service to the adjacent proper
Rt 78, Eastbound Roadway Rehabilitation, Construction
San Dimas & Soldier Creek Cabin Demolition and Historic Building Restoration in Angeles National Forest and Forestwide Trail Maintenance in Angeles and San Bernardino National Forests
Facilities and Trails Work in Angeles & San Bernardino National Forests
Environment, Conservation and Wildlife Organizations
Head Start Quality Improvement and COLA (ARRA)COLA EHS/HS All Early Head Start and Head Start staff received a one time 1.84% increase in Cost of Living based on their present wages listed in the Early Head Start and Head Start budgets.  This i
Full Year Head Start - Part Day & Handicapped
WEST CENTRAL MISSOURI COMMUNITY ACTION AGENCY
FY2009 ARRA COLA/QI - This action awards a cost of living adjustment (COLA) increase of 1.84% in the amount of $57,526 for Head Start and $12,991 for Early Head Start.  These funds must be obligated over the 12 month period following the effect
FY2009 ARRA COLA/QI To improve salaries and fringe and provide additional training to staff, tuition assistance, funding for CDA classes and hire 3 additional staff, used for purchase of child safety upgrades, Purchase child assessment system
FY2009 ARRA Cost of Living Adjustment(COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act.
Head Start FY2009 ARRA COLA/Quality Improvement
Head Start Program - Early Childhood Development Program.
OZARKS AREA COMMUNITY ACTION CORPORATION
FY 2009 ARRA COST OF LIVING ADJUSTMENT / QUALITY IMPROVEMENT FOR HEAD START AND EARLY HEAD START PROGRAM IN 10 COUNTIES IN SOUTHWEST MISSOURI SERVING 1538 CHILDREN; GRANT PROVIDED COLA WAGE INCREASES FOR STAFF, SECURE ENTRIES FOR 9 CENTERS, AND
NORTHEAST MISSOURI COMMUNITY ACTION AGENCY
FY 2009 ARRA COLA/QI - A cost of living adjustment increase of 1.84% for Head Start and Early Head Start.  Quality improvement funds awarded to Head Start and Early Head Start.  QI funds used to increase salaries for positions that were not pay
FY2009 ARRA COLA/QI Head Start COLA R022/Overall purpose: Restore staff positions cut or reduced due to funding restraints; a part-time Family Support Worker, duty days for Coordinators, and all Teacher Assistants and Bilingual Teacher Assistan
UNIVERSITY OF KANSAS MEDICAL CENTER RESEARCH INSTITUTE, INC.
Project EAGLE EHS provides early education and comprehensive family support services to low-income pregnant women and children ages birth to three, and their families. The goal is academic readiness and healthy development for children at risk
CHILDREN'S THERAPY CENTER OF PETTIS COUNTY INC
Early Head Start Quality Improvement and COLA  COLA was used to give staff payroll increases.  These increases are permanent.  The QI funds were used to cover ongoing program expenses that exceeded the federal continuation funds.
This ARRA Head Start grant awards funds to expand Head Start services to 60 additional children in Sedgwick County, Kansas.  The expansion targets the three year old population and focuses on serving children who meet age, income and/or categor
The awards provides for ARRA Head Start Expansion funded to serve 12 children in a new county (Rooks County). The Head Start program proved family-centered services for low-income families with young children (ages 3 to 5) to promote the health
I-80 East Bound West of Madison Ave to Polifly Rd Resurfacing, Construction
Title: “Collaborative Research: A 3D Seismic Study of the Pacific-North American Plate Boundary in Southern California”  Description: “We will use data from 34 long-duration, broadband Ocean Bottom Seismometers (OBS) in a passive seismic
COLLABORATIVE RESEARCH: A 3D SEISMIC STUDY OF THE PACIFIC-NORTH AMERICAN PLATE BOUNDARY IN SOUTHERN CALIFORNIA
This proposal provides for the continued operation of the University of Wyoming (UW) King Air (UWKA, http://www.atmos.uwyo.edu/n2uw) research aircraft and the Wyoming Cloud Radar (WCR, http://www.atmos.uwyo.edu/wcr) as a national facility. This
This project will quantify the electrodynamic coupling between the lower atmosphere, the ionosphere, and the magnetosphere by performing an observational and modeling study focused on terrestrial gamma-ray flashes TGF. The investigation will in
CEDAR: Mechanisms and Effects of Terrestrial Gamma-ray Flashes
The West Antarctic Ice Sheet is believed to be vulnerable to climate change as it is grounded below sea level, is drained by rapidly flowing ice streams and is fringed by floating ice shelves subject to melting by incursions of relatively warm
History of, and Mechanisms Leading to, Post-LGM Retreat of the West Antarctic Ice Sheet
Steig/0837990This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).This award supports a project to obtain a ~100,000-year record of 17O-excess from the WAIS Divide ice core, currently being drilled in
Record of the 17O-excess of H2O in the WAIS Divide ice core
Through plate tectonics and subduction, Earth recycles oceanic crust and lithosphere into its mantle. The down going oceanic crust carries H2O, which, when released into the overlying mantle wedge, causes melting that results in arc volcanism.
The Effect of Trace Amounts of H2O on the Rates and Mechanisms of Olivine and Enstatite Phase Transformations in Earth's Mantle Transition Zone
The overall purpose of this project is to improve basic scientific knowledge of how crystalline solids deform, with a focus on earth materials and the mineral quartz in particular. The ability to predict the response of crystalline solids to fo
In-situ Synchrotron X-ray Diffraction Study of Quartz Deformation.
Investigation of the temporal and spatial evolution of volcanism related to giant calderas in the Central Andes through detailed dating and chemical analysis of zircon crystals.
COLLABORATIVE RESEARCH:  TIMESCALES OF CONTINENTAL MAGMATISM AND DEVELOPMENT OF LARGE SILICIC SYSTEMS:  INSIGHTS FROM ACCESORY PHASES
The Amundsen Sea Polynya is areally the most productive Antarctic polynya, exhibits higher chlorophyll levels during peak bloom and greater interannual variability than the better-studied Ross Sea Polynya ecosystem. Polynyas may be the key to u
Collaborative research aboard Icebreaker Oden: ASPIRE (Amundsen Sea Polynya International Research Expedition)
This award supports a project to use the WAIS Divide deep core to investigate the Last Deglaciation at sub-annual resolution through an integrated set of chemical and biological analyses. The intellectual merit of the project is that these anal
Collaborative Research: Integrated High Resolution Chemical and Biological Measurements on the Deep WAIS Divide Core
Physiological processes provide the functional connection between the genome and the environment. Over the years, a rich literature has emerged concerning physiological response to variable environments; however, much less is known about how ge
Can a small mosquito tell us something new about evolutionary physiology? Genetics of photoperiodic response in the pitcher-plant mosquito, Wyeomyia smithii.
The funds awarded will purchase a MALDI mass spectrometer that will support the exploding numbers of diverse and interdisciplinary research projects requiring analysis and characterization of synthetic macromolecules and biomacromolecules that
CRIF: MU-Acquisition of a Cyber-Enabled Matrix Assisted Laser Desorption/Ionization (MALDI) Mass Spectrometer
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 11-5).  With support from the Chemistry Research Instrumentation and Facilities:  Multiuser program (CRIF:MU), the Department of Chemistry and Biochemistr
The Madden-Julian Oscillation (MJO) is the dominant form of atmospheric intraseasonal variability in the climate system. It interacts with and influences a wide range of physical weather and climate phenomena (e.g., monsoon onsets and breaks, E
COLLABORATIVE RESEARCH: EXPLORING THE CHEMICAL REACH OF THE MADDEN-JULIAN OSCILLATION: SATELLITE/IN-SITU DATA ANALYSIS AND CHEMISTRY/TRANSPORT MODELING
The thin, rocky shell of the Earth, the lithosphere, is broken into a mosaic of thin plates that are in constant motion. Along some boundaries between plates, one slides beneath the other and is consumed in a process known as subduction. Most o
Collaborative Research: SERPENT: Serpentinite, Extension and Regional Porosity Experiment across the Nicaraguan Trench
This project focuses on advancing understanding of several critical issues in atmospheric ice nucleation (IN), one of the most basic processes affecting precipitation and impacting the radiative properties of cold clouds. Incomplete understandi
Collaborative Research:  Laboratory and Ground-Based Studies Addressing Unresolved Aspects of Atmospheric Ice Nucleation.
We can not perceive other minds the way we perceive our own. So, we can not look into the mind of a patient in a persistent vegetative state to see if 'someone is home,' just as we can not really know what is going on in the mind of an infant o
Locally rare species are expected to have a survival advantage because rarity reduces their risk of damage from pathogens. This 'rare-species advantage' may help maintain plant diversity in natural systems and explain how introduced plant speci
Rare-species advantage: consequences of phylogenetic and numerical rarity of hosts for disease pressure and pathogen communities
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).The coiled coil of myosin is among the longest in nature and contains functionally diverse elements that will be characterized using a newly develo
Gravitational Force Spectroscopy of Single Myosin Molecules
Recently, there has been a paradigm shift in microbial metabolism: the focus is no longer solely on the elucidation of how substrates are converted to products (inputs and outputs), but rather also includes a concerted effort to understand the
(ARRA) Carbon flow through the etylmalonyl-CoA pathway
Understanding the processes that produce and maintain genetic variation is a critical goal of modern biology.  Of the many behavioral processes that may influence genetic variation, few are as directly influential as mate choice.  Choice of a r
Individual Reproductive Decisions: Behavioral Mechanisms
Evolutionary biologists have developed a number of mathematical models to understand the process of selection on traits that arises from partner preferences. However, tests that can be used to discriminate among these models are lacking, in par
Testing models of selection with data on behavioral isolation
Intellectual merit.  Membrane proteins are of tremendous importance for biology and pharmaceutical industry. However, their X-ray high-resolution structures are still difficult to obtain due to the challenges in crystallization posed by the pre
High-Resolution Structures and Ligand-Induced Conformational Changes of Membrane Proteins by Solid-State NMR: Methodology Development and Applications
The goal of this research is to determine the mechanism of polypeptide translocation catalyzed by the hexameric E. coli ClpA motor protein.  Motor proteins are essential enzymes for a variety of cellular processes that require mechanical work.
KINETIC MECHANISM OF CLPA CATALYZED POLYPEPTIDE TRANSLOCATION
This multidisciplinary project involves a combination of paleomagnetic, high precision geochronologic, stable isotope, and sedimentologic work on sequences of Late Permian to earliest Triassic age in westernmost Texas and eastern New Mexico.  T
Collaborative Research: Terrestrial Paloenvironmental Record Through the Permian-Triassic Transition of Texas and New Mexico
With National Science Foundation support, Dr. Kathryn Bock will conduct three years of psycholinguistic research on the cognitive processes involved in producing number agreement in spontaneous speech. The project will investigate whether and h
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). This project involves a collaboration between scientists at the Berkeley Geochronology Center, University of California, University of New Mexico,
Collaborative Research: Terrestrial Paleoenvironmental Record Through the Permian-Triassic Transition of Texas and New Mexico
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  At the culmination of the lithospheric accretion that built the Appalachian Mountains (250-320 million years ago) the lithosphere of another cont
Collaborative Research: Understanding Lithospheric Suturing and Passive Margin Development Beneath the Southeastern U.S.
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  It is currently unclear what paradigms will be most appropriate for programming autonomous robots. There are many approaches to robot control, su
CAREER: Robot Learning from Multivalued Demonstration
Intellectual Merit. When new proteins are synthesized, they emerge in an extended, linear conformation and must be folded into their final, three-dimensional shapes before they acquire function. The cellular network responsible for supervising
CAREER: Understanding the Logic of Chaperone-Assisted Protein Folding in Cells
As semiconductor technology enters the nanometer regime, modern VLSI systems face an unprecedented power crisis. Although existing power management methods have proven to be successful in many IC modules, as structural and algorithmic complexit
CAREER: Analog Computation Based Real-Time Global Power Management: from Devices to Multi-Core Systems
This project is directed toward the discovery of new chemistry for S-nitrosothiols, which are important nitric oxide metabolites. The lability of the sulfur-nitrogen bonds often makes S-nitrosothiols in proteins cumbersome to measure accurately
CAREER: Novel Reductive Ligations of S-Nitrosothiols
Career: an Innovative Performance-Based Simulation Framework for High-Rise Building against Wind Hazards
Head Start promotes the school readiness of low income children through the provision of comprehensive health, developmental and family services.  The Region 10 Education Service Center Head Start program received 54 additional slots to serve t
PI: Webster, Thomas Proposal Number: 0730906  Novel materials are needed to restore functions to persons with disabilities since current materials have not sufficed. Nanotechnology, broadly defined as the use of materials with at least one di
Carbon Nanotubes Impregnated with Stem Cells to Return Motor Skills
I-76 OVER UPRR/SH-224 BRIDGE REPLACEMENT
Construction of a Regional Technology Center and educational facility for the Canyon Owyhee School Service Agency (COSSA).
Regional Technology Center for Canyon Owyhee School Service Agency
Purchase one fork lift and one crane for use at the Port of Bristol Bay.  Also, purchase attachments for equipment.
Rt 78, Union/Essex Rehabilitation, Contract C, Construction
US 45A FM APPRX 9 MI N OF NOX CL TO THE CLAY CL
ARRA COLA and Quality Funds will be used to increase the compensation and benefits of staff through a cost of living adjustment to improve the overall quality of the program and provide professional development to Grantee and Delegate staff on
TRI-COUNTY CHILD AND FAMILY DEVELOPMENT COUNCIL INC
ARRA COLA and Quality Improvement funding consistent with the provisions of Section 640(a)(5) of the Head Start Act. Funds were used to increase the wages and fringe benefits of all staff members (135) and to enhance the professional developmen
These funds will be used to support some of our goals and to enhance the over-all quality of our staff and ultimately the program services for the children and families that we serve in Wyandotte County. There are two primary uses for these ARR
FY 2009 ARRA COLA/QI. $60,519 in Cost of Living Adjustment (COLA)funding to increase the hourly rate of pay in the amount of 1.84% (a funded mandate)for 120 Head Start staff for a 12 month period beginning on August 24, 2009 and ending on Augus
FY 2009 ARRA COLA & QUALITY IMPROVEMENT. Temporarily increase hourly rates for Head Start employees.  Paint Rock Port Head Start Center. Hire Bus Monitors and Center Aides.
SOUTH CENTRAL IOWA COMMUNITY ACTION PROGRAM, INC.
The total funding of $135,809 was centered around several items . A 1.8% cost of living increase was implemented to raise the wages of all Head Start and Early Head Start employees to a more competitive level for the surrounding community. We a
FY2009 ARRA COLA/QI: This is the American Recovery and Reinvestment Act (ARRA) Cost of Living Adjustment (COLA) and Quality Improvement funding consistent with the provisions of section 640(a)(5) of the Head Start Act.  COLA is necessary to kee
Head Start Quality Improvement and COLA (ARRA)to provide for a special needs aide, and help supplement a wage for a certified teacher in order to improve program quality, and increase wages to meet the cost of living adjustment.
The purpose of this award is to enhance Head Start services for the 10 counties that Northeast Kansas Community Action Program serves.  NEK-CAP, Inc., runs Head Start Centers located in Atchison, Brown, Doniphan, Jackson, Jefferson, Leavenworth
FY2009 ARRA COLA/QIHead Start and Early Head Start
NORTH IOWA COMMUNITY ACTION ORGANIZATION
This award provides for ARRA Quality Improvement Funding in the amount of $120,937 consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start Program.  Head Start promotes the school readiness of low-income chi
The ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640 (a)(5) of the Head Start Act will serve 553 Head Start children and 40 Early Head Start children in the Iowa counties of Cl
Head Start and Early Head Start FY2009 ARRA COLA/QI
Cost of Living Award increases for 79 staff for staff retention; creation of 1 full time position; Quality Improvement expanded employment hours for 35 staff; early childhood college coursework to attain higher credentials for teachers, teacher
ARRA funding for Head Start and Early Head Start COLA and ARRA funding for Head Start and Early Head Start Quality Improvement.This award provides for ARRA Cost of Living Adjustment and Quality Improvement Funding consistent with the provisions
Youth in Need was awarded a 1.84 COLA for its HS/EHS staff, for a period of 12-months beginning July 1, 2009. This equated to a sum of $79,140. This funding allowed YIN to more fairly compensate its HS/EHS employees, and enhanced the opportunit
Head Start Quality Improvement -  Adding 3 Family Advocates.  Community and Self Assessments indicated need for increase family services.  All paraprofessional have to have CDAs or equivalent by 9/2013.  ARRA funds used to pay tuition and hourl
FY 2009 ARRA Cost of living adjustment (COLA), and Quality Improvement (QI) Funding as consistent with the provisions of Section 604(a)of the Head Start Act. The funds support permanent cost of living increases for staff (1.84%), allowed to hir
Temporary COLA = 48100-48100                                 Quality Improvement 48200-48200
FY2009 ARRA COLA/Quality - Head Start ARRA funds are allocated to a variety of purposes and activities, including cost-of-living allowances for Head Start  staff and quality improvement for the Head Start program including technology upgrades a
Head Start Expansion ARRA HS ARRA Expansion Continued serves to 36 Head Start children in a center base program.  Our goals are to provide quality HS comprehensive serves to 36 additional HS children & families in Hall County.  No changes in pr
I-80 in Lander County from 1.10 ME of the HU/LA County Line to 3.4 ME of HU/LA County Line
Land is an integral component of the climate system and changes in land cover can significantly influence terrestrial weather and climate. This project aims to investigate regional-scale vegetation-atmosphere feedbacks over seasonal timescales
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). This award supports a project to reconstruct the past physical and chemical climate of Antarctica, with an emphasis on the region surrounding the
Collaborative Research: Antarctic climate reconstruction utilizing the US ITASE ice core array
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  Both the mechanisms of growth of orogenic plateaus and the processes that control or limit their growth remain controversial. Within currently ac
Controls on Growth of the Puna Plateau, Northwestern Argentina
Rationale: Soil water exerts a critical control on weather, climate, ecosystem, and water cycle, and hence is crucial for many fields within atmospheric sciences and related disciplines. A serious handicap in soil moisture measurements is the m
MSI: The COsmic-ray Soil Moisture Observing System (COSMOS)
Intellectual Merit. This project will address the time scales of assembly and the organization of batholith-scale silicic magma systems in the Altiplano Puna Volcanic Complex (APVC) of the Central Andes. The proposed work builds on recent effor
Collaborative Research: Timescales of Continental Magmatism and Development of Large Silicic Systems: Insights from Accessory Phases
This award supports a modeling study of the processes in West Antarctic grounding zones, the transition from ice resting on bedrock to ice floating on the ocean surface with an eye toward understanding the interrelated causes of rapid change in
Mass Transit: Controls on Grounding and Ungrounding at Marine Ice Sheet Outlets
The solar wind - magnetosphere - ionosphere system and the space weather phenomena it controls is a complex and dynamic environment that has increasing recognition of potentially impacting critical human technological infrastructure. To be able
Polar Experimantal Network for Geospace Upper-atmosphere Investigations (PENGUIn): Interhemispheric Investigations along the 40 Degree Magnetic Meridian
The scheduled field campaigns aboard the Swedish icebreaker Oden in November-January of 2010 will provide an unprecedented opportunity to sample the sea ice microbial community in a region of the Antarctic ice pack that has received very little
Oden Science: Sea Ice Ecology in the Amundsen and Eastern Ross Sea
In this proposal, we seek to determine whether snow is an important influence on soil microbial ecology and linked biogeochemical cycling.  We propose to conduct fieldwork at the landscape scale (repeated aerial photography during the summer to
Collaborative Research: The Role of Snow Patches on the Spatial Distribution of Soil Micorbial Communities and Biogeochemical Cycling in the Antarctic Dry Valleys
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). The investigators will examine competing hypotheses for the mechanism of extension and creation of the Transantarctic Mountains, and evolution of
RIFT MECHANISMS & THERMAL REGIME OF THE LITHOSPHERE ACROSS BEARDMORE GLACIER REGION, CENTRAL TRANSANTARCTIC MOUNTAINS FROM MAG
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  The Amundsen Sea Polynya is really the most productive Antarctic polynya, exhibits higher chlorophyll levels during peak bloom and greater intera
Collaborative Research Aboard Icebreaker Oden:  ASPIRE (Amundsen Sea Polynya International Research Expedition)
The Ross Sea is a highly productive area within the Southern Ocean, but it experiences substantial variability in both physical (temperature, ice concentrations, salinity, winds, and current velocities) and biogeochemical (chlorophyll, producti
Collaborative Research: Seasonal Evolution of Chemical and Biological Variability in the Ross Sea.
Collaborative Research aboard Icebreaker Oden: ASPIRE (Amundsen Sea Polnya International Research Expedition)
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 11-5). The RAGES project (Robotic Access to Grounding zones for Exploration and Science) is one of three research components of the WISSARD (Whillans Ice
Collaborative Research:  Integrative Studey of marine Ice Sheet Stability and Subglacial Life Habitaats - Robotic Access to Grounding-zones for Exploration and Science (RAGES)
This project will deploy a new Fabry-Perot Interferometer (FPI) at the U.S. Palmer Station located in the Antarctic Peninsula. The FPI will observe mesospheric and thermospheric neutral winds and temperatures using multiple nightglow emissions
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). The PENGUIn team will continue investigating in depth a multi-scale electrodynamic system that comprises space environment of Planet Earth (geospa
Collaborative Research: PENGUIn - A High-Latitude Window to GeospaceDynamics
This grant provides funds for upgrading an existing nuclear magnetic resonance (NMR) spectrometer that will provide the only cryoprobe at Texas A&M University.  The cryoprobe will have significant impact on research and education both intra- an
Acquisition of a Cryoprobe for a NMR Spectrometer
Research has shown that being excluded from social groups is endemic to peer interactions, relationships, and groups from early childhood through to adulthood. In fact, exclusion constitutes a basic feature of group dynamics that derives from t
Social Reasoning, Subjective Group Dynamics, and Children's Evaluations of Exclusion
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). With this award from the Chemistry Research Instrumentation and Facilities Multiuser Program (CRIF:MU), Professor Paul B. Hopkins and colleagues K
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  With this award from the Chemistry Research Instrumentation and Facilities: Multiuser program (CRIF:MU), Alec M. Wodtke from the University of Ca
Acquisition of a Gas Chromatograph Time-of-Flight Mass Spectrometer for Small Molecule Analysis with Cyber Enabled Remote Access for Research, Education, and Outreach
Upgrade of a 300 MHz NMR Spectrometer for Research and Teaching NSF provided funds to replace the console and upgrade a research instrument originally purchased in 1994.  The instrument, an NMR spectrometer, is used by researchers in Chemistry
Upgrade of a 300 MHz NMR Spectrometer for Research and Teaching
Collaborative Research: Imaging, Estimation, and Analysis of Density Distributions in the Conjugate Polar Ionospheres
'Spin Transport and Dynamics in Nanostructures' Electron spin in nanoscale and low-dimensional systems provides prototypical quantum degrees of freedom, which garnered tremendous attention in recent years. Spins play a central role as building
CAREER:  SPIN TRANSPORT AND DYNAMICS IN NANOSTRUCTURES
Collaborative Research: Melting of Carbonate-bearing Sediments in Subduction Zones
Division of labor occurs at all levels of biological organization: for example, cells in a multi-cellular organism just as workers in a social insect colony may specialize on particular tasks. Such specialization can lead to morphological diffe
Adaptive distribution of morphological specialists in social insects: New insights into the evolution of division of labor
The productivity of many aquatic ecosystems is often limited by the availability of a key nutrient. In the oceans and in some lakes nitrogen is often that key limiting nutrient. Nitrogen, which is critical for life, occurs in diverse chemical f
The Importance of Molybdenum Speciation to Nitrogen Fixation and Assimilation in Lakes
We request funds to upgrade our geophysics research group computer system by purchasing two Dell workgroup servers, two 14 Tb fast RAID disk arrays, three fast workstations, and associated accessories. These acquisitions will allow us to standa
ACQUISITION OF A NEW LINUX-BASED COMPUTER SYSTEM FOR GEOPHYSICAL RESEARCH
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).Single carbon (C1) compounds commonly found in the environment include methane, methanol, methylated amines, halogenated methanes, and methylsulfon
C1-oxidation pathways in proteobacteria: function and regulation
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).    Quantitative measurements of the global electric circuit, in which lightning plays a key role, are important both in terms of basic description
Merging of Observations and Models for the Earth's Schumann Resonances
Investigation of the evolution of leaf form in Viburnum (Adoxaceae), a clade of c. 168 shrubs and trees that display a striking diversity of many key leaf traits.
COLLABORATIVE RESEARCH: THE EVOLUTION OF LEAF FORM IN VIBURNUM (ADOXACEAE)
Intellectual Merit: The ability of anaerobic prokaryotes to perform dissimilatory selenium reduction is a remarkable biological adaptation that allows selenium respiring microorganisms to populate ecological niches in Earth?s subsurface. In lab
Molecular Studies of Dissimilatory Selenium Reduction by Subsurface Microorganisms
Intellectual merit: How the accurate duplication of genetic material and its faithful segregation to daughter cells is coordinated in multi-cellular organisms is an important question that remains to be clearly understood. In eukaryotic cells t
Investigating the Role of Orcs in Chromatin Organization and in Mitotic Progression
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). The Pacific Northwest, and Washington State in particular, are characterized by a subduction zone environment called the Cascadia subduction syste
COLLABORATIVE RESEARCH: AN EARTHSCOPE MAGNETOTELLURIC SURVEY OF THE SOUTHERN CASCADIA SUBDUCTION SYSTEM, WASHINGTON
this self-presentation strategy is one where individuals shift, suppress, or otherwise avoid discussing topics that are closely associated with their group membership during interracial interactions and is designed to reduce any negative react
The Costs of Covering: Psychological and Physiological Implications of Managing a Stigmatized Identity
Half of the 20 most significant inventions of the 20th century would not have materialized without glass. The solutions to 11 of the 14 grand engineering challenges of this century depend on the availability of glass either as a support materia
International Materials Institute for New Functionality in Glass (IMI-NFG) - Phase II
Debris flows initiating in the upper reaches of glaciated valleys of the Cascade strato volcanoes are typically associated with intense, multi-day rain events being brought in by the subtropical jet stream. Recent investigations suggest that th
Climatic and Geomorphic Triggering Mechanisms of Cascadian Periglacial Debris Flows
Much of the land area of Washington, Oregon, and California was added to continental North America during the last 200 million years. Exactly how this dominantly oceanic lithosphere accreted to the continent is not well understood, although it
Collaborative Research: Deformation and Magmatic Modification of a Steep Continental Margin, Western Idaho-eastern Oregon
School of Earth and Env. Sci., Washington State Univ.
Biological Research Collections -   This project will develop the first computerized database of the 7,600 specimens of birds and mammals in the John Wesley Powell-Dale Birkenholz Natural History Collections at Illinois State University.  This
Databasing of the Bird and Mammal Collections at Illinois State University
Illinois State University-Research & Sponsored Programs
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).    Magnetic reconnection plays a fundamental role in nearly all magnetized plasmas as it enables magnetic energy to be converted into high speed f
CAREER Three-Dimensional Onset and Evolution of Spontaneous Reconnection
UNIVERSITY OF NORTH CAROLINA AT CHARLOTTE
CAREER: A Structure-Based Approach to Transcription Factor-binding Site Prediction via Protein-DNA Docking  This is a CAREER award to support the research of Dr. Juntao Guo in the College of Computing and Informatics at the University of North
CAREER: A Structure-Based Approach to Transcription Factor-binding Site Predicti
The PI plans to obtain new examples of gauge/gravity dualities and apply them to address open problems in standard model, nuclear, and condensed matter physics.The PI's research focuses on the AdS/CFT correspondence and more generally on gauge/
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). In this CAREER project supported by the Theoretical & Computational Chemistry Program of the Chemistry Division, Xiasong Li of the University of W
CAREER: Advancing Electronic Structure Theories for Properties and Dynamics of Large Scale Systems:  Developments and Applications Integrated with Educational Efforts
'Intellectual Merit Iron in its unbound state is potentially toxic to organisms; therefore, sophisticated mechanisms are in place to traffic this essential metal ion, especially in the mitochondrion. The mitochondrial iron chaperone protein fra
CAREER: Modecular Interactions of the Mitochondrial Iron-Chaperone Frataxin
The mail goal of the proposal is to develop a practical computational framework for the response of a complex chaotic nonlinear multiscale dynamical system to changes in external forcing parameters. It is based on the PI's recent successful eff
Career: Predicting Global Climate Change Through Fluctuation Dissipation A Practical Computational Strategy For Complex Multiscale Dynamics
An intricate network of signaling pathways controls reproductive development in plants. However, the basic mechanisms that have evolved to control signaling pathways, and thus variation in the onset of reproduction across different growing habi
CAREER: Fundamental Advancement in Understanding of Tree Reproduction and Development of Educationa
'CAREER: Information Theory and Coding for Wireless Broadcast Networks  Broadcast is a fundamental nature of wireless communication. With appropriate coding architecture, the broadcast nature of wireless communication can be used to the advanta
CAREER: Information Theory and Coding for Wireless Broadcast Networks
Real-world software systems are large, complex artifacts built up over multiple layers of abstraction using diverse collections of components. Though individual components are often reusable, code that manages interactions between components se
CAREER: From Incidental Algorithms to Reusable Components: Managing the Emergent Complexity of Large-Scale Software Systems
As computers become more powerful, the limiting factor for building software systems is shifting away from the underlying computer's performance limitations to the software's inherent complexity. One way to cope with this complexity is to use s
CAREER: Lightweight, Blame-Aware Contract Checking
'Scheduling policies are at the heart of all computer systems and are a key determinant of system performance. The goal of this project is to provide a rigorous foundation for modern scheduling design issues. The project includes two main dire
CAREER: Towards a rigorous foundation for scheduling in modern systems
Description: The semiconductor industry is likely to see several radical changes in the fabrication and device technologies in the next decade. Conventional after-the-fact changes to design methodologies and tools to technology leads to wasted
CAREER: CO-OPTIMIZATION OF INTEGRATED CIRCUIT DESIGN AND MANUFACTURING
The Analytical and Surface Chemistry Program supports this CAREER award to Professor Kevin Schug of the University of Texas - Arlington, to devise means of quantitatively assessing noncovalent binding interactions by electrospray ionization mas
CAREER: Quantitative Characterization of Noncovalent Interactions by Mass Spectrometry - A Systematic Approach
'The goal of this CAREER project is to develop an integrated research and educational program in molecular systems biology (MSB). This project focuses on soluble signal-mediated signaling between bacteria and human cells, termed inter-kingdom (
CAREER: Inter-kingdom Signaling as a Paradigm for Molecular Systems Biology
PROJECT SUMMARYCAREER: Nano Tip Sensor for Rapid Detection of Dissolved DNA for Environmental Monitoring'This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).'One of the critical challenges in environ
CAREER: Nano-Tip Sensor for Rapid Detection of Dissolved DNA for Environmental Monitoring
This project will investigate the formation of water molecules and the growth of ice in conditions that simulate the interstellar medium and planetary environments. Water is a well-recognized prerequisite for the complex chemistry linked to the
Investigation of the Formation of Water and of the Growth of Ices on Dust Grain Analogues
Funds are provided to examine the nature and cause of short-term ice sheet velocity changes. The work field would occur near Swiss Camp, Greenland and focus on the interactions between the ice sheet, the atmosphere and the bed through an integr
Collaborative Research: Subglacial controls on Greenland Ice Sheet marginal acceleration
Collaborative Research: Tracking Galaxy Growth with  200,000 Spectroscopic Redshifts.  This project is to analyze the PRIsm MUlti-object Survey (PRIMUS), a new wide-area faint spectroscopic redshift survey out to z=1, consisting of over 200,000
Collaborative Research: Tracking Galaxy Growth with 200,000 Spectroscopic Redshifts
Improved forecasting of orographic precipitation requires continued integration of theory, field studies, and long term observations. While much of the previous work on orographic precipitation has focused on steady-state processes, little work
Collaborative Research: Intermittent and Steady State Processes in Orographic Precipitation
Dr Coil, Dr Blanton and Dr Eisenstein will analyze their large survey of 300,000 galaxies, to understand the growth and evolution of the stellar bodies of galaxies over the past several billion years in the context of the current standard Cold
The focus of this research is the development of a comprehensive theory to analyze (inverse) scattering problems with waves in random media generated by (random) ambient noise sources. In particular, the investigators are interested in the anal
Collaborative Research: Stochastic and Multiscale Analysis of Ambient-Noise Generated Scattered Waves and Imaging
This proposal explores several areas where algebraic geometry interacts with quantum field theory and string theory: the Geometric Langlands Program, on the math side; heterotic string phenomenology and F theory, in physics; and the superstring
Research Proposal in Algebraic Geometry and String Theory
This Small Business Innovation Research Phase I research project will test the feasibility of increasing diesel fuel economy while reducing soot to below EPA emissions standards for diesel exhaust by adjusting fuel injection timing using feedba
SBIR Phase I: Airborne Soot Sensor for Improving Fuel Efficiency and Reducing Pollutants
'This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).'   This award provides funding for a 3 year standard award to support a Research Experiences for Teachers (RET) in Engineering Site program at Em
Research Experiences for Teachers: Aviation and Aerospace
Dr. Wechsler and her team will explore how hydrogen gas is reionized by the ultraviolet radiation from the earliest stars and active galactic nuclei, and how that affects star formation in small galaxies. Standard Cold Dark Matter cosmologies p
Reionization, Environment, and the Galaxy Content of Milky-Way Mass Halos
The interstellar medium (ISM) plays a vital role in the ongoing cycle of stellar birth and death, and galactic evolution. However the role of interstellar matter, from how its properties are influenced by stars to how, in turn, its properties i
ARRA Measuring Interstellar Temperature and Ionization Variations Using Observations of Faint Diffuse [OII] Emission
The principal investigators propose to investigate flexibilityand rigidity questions that are central to the character ofsymplectic and contact topology by exploring knotting phenomenaof Lagrangian and Legendrian submanifolds. Approachingsymple
Collaborative Research: RUI: Knotting Phenomena in Contact and Symplectic Topology
This research will investigate the jet structure and energy generation of quasars and other active galactic nuclei (AGNs), microquasars, and gamma-ray bursters, all of which are believed to be powered by rotating (Kerr) black holes. However, th
Theoretical and Numerical Investigation of a Unified Astrophysical Rotating Black Hole Model for Active Galactic Nuclei, Microquasars, and Gamma-Ray Bursters
This work will document observed changes in the hydroclimatology of the Siberian region, attribute these changes to specific physical mechanisms in the context of climate change, and study the impact of those changes from the regional to the he
Collaborative Research: Analysis and attribution of changes in Siberian hydroclimate and implications for the future
The Chukchi Borderland is a block of extended continental crust embedded in the oceanic crust of the Canada Basin. As the piece that does not fit the simple 'windshield wiper' model for the Mesozoic opening of this basin, it figures prominently
Plate Boundaries Around the Chukchi Borderland; An Integrated Geophysics Cruise to Test Models for the Formation of the Canada Basin
This Small Business Innovation Research Phase I project is to design, synthesize, manufacture, and test high-performance polymeric composite structures based on commercially proven resins, long fibers and nano-sized functional particles. Long f
Nanomaterials Reinforced Light-Weight Structural Composites
This Small Business Innovation Research Phase I project will result in a suite of microbial source tracking assays to provide cost-effective identification of fecal contamination sources in surface waters. Beach closures and advisories exceeded
SBIR Phase I: Microbial Source Tracking Using Mitochondrial DNA for Identification of Contaminant Sources
This project focuses on the synthesis and characterization of two new classes of conjugated oligomers, as the next-generation technologies require the manipulation of charge  and energy of new organic materials with unusual conjugated features
ortho-Phenylene oligomers and Graphene Nanoribbons
Peter Rossky of the University of Texas, Austin, is supported by an award from the Theoretical and Computational Chemistry program to carry out research on quantum mechanical simulation of chemical dynamics in condensed phases. The research foc
QUANTUM SIMULATION OF CHEMICAL DYNAMICS IN CONDENSED PHASES
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). This Research award in the Inorganic, Bioinorganic and Organometallic Chemistry program supports work by Professor Linda Doerrer at Boston Univers
Synthesis and Reactivity of Fluorinated High Oxidation State Complexes
Intellectual merit: Zircon is a widespread component of siliceous igneous rocks and hosts a wide range of trace elements (e.g., REE) and isotopic species (e.g., O, Hf, Pb and U) that are useful for geochronologic, petrogenetic and geochemical s
Trace Element Partitioning in Magmatic Zircon: Empirical and Experimental Studies at Sub-micron Scales
Drs. T. Douglas Price and James H. Burton will use support from the National Science Foundation to replace the primary scientific instrument in the Laboratory for Archaeological Chemistry at the University of Wisconsin-Madison. The lab will pur
ARRA LABORATORY SUPPORT AWARD: OPTICAL EMISSION SPECTROMETER FOR THE LABORATORY FOR ARCHAEOLOGICAL CHEMISTRY
Hydrologic environments are open and complex, rendering them prone to multiple interpretations and mathematical descriptions regardless of the quantity and quality of available data.  This recognition has led to a growing tendency among hydrolo
Impact of Calibration Data on Evaluating Plausibility of Alternative Groundwater Models
Prof. McGown and her students will study the processes that govern affinity protein capture at aptamer-modified surfaces using affinity MALDI mass spectrometry in combination with surface plasmon resonance (SPR) spectroscopy and imaging, and wi
Affinity Protein Capture by Immobilized DNA at Surfaces
Technical Description: In the shallow crust, most of the strain at plate boundaries is relieved during sudden rare large earthquakes. Below the shallow locked portion, strain has often been thought as being relieved through steady creep, or, in
How Deep Do Ruptures Penetrate in Large Earthquakes?
Prairie pothole lakes (PPL) are important hydrologic features in the glacial till of the Upper Midwest. A number of these lakes have  developed unique water chemistries, including extremely high (10?s to 100?s of millimolar) levels of sulfate.
(ARRA) Collaborative Research: Redox processes in the sedimentary porewaters of prairie pothole lakes: Implications for the attenuation of pesticides
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5)  H. E. Stanley of Boston University is supported by an award from the Theoretical and Computational Chemistry program to carry out research concern
Understanding Static and Dynamic Heterogeneities in Confined Water
Chemistry of oceanic island basalts (OIBs) reflects the complexity of compositions and processes in the Earth's mantle. Isotope and trace element geochemistry have established that parent lithologies of OIBs in the Earth's mantle are heterogene
Melting of Carbonated MORB-like Eclogite and Genesis of Ocean Island Basalts
'This project, which is a collaboration between researchers at Western Washington University, the University of Alabama at Tuscaloosa, and Boston University, is focused on improving our understanding of what happens when rocks are heated, press
Collaborative Research: Developing a Practical and Quantitative Method for Measurement of Metamorphic Porphyroblast Crystallization Kinetics and Strain Rate
In this work we explore the elastic and viscoelastic responses of the solid earth related to climate induced surface load changes. The  climate changes and associated loads occur at time scales ranging from annual hydrological cycles at one ext
(ARRA) Collaborative research: Probing the earth system in Patagonia: Crustal motion in relation to tectonics, earth structure, the hydrological cycle and climate change
The Analytical and Surface Chemistry (ASC) Program of the Division of Chemistry will support the research project of Prof. Nathan Lewis of California Institute of Technology (Caltech). Prof. Lewis and his students will develop a detailed under
Achieving Molecular Level Control over the Chemical, Electrochemical, and Electrical Properties of Crystalline Si Surfaces
INTELLECTUAL MERITS. The extraction of melts from the lower crust and their subsequent emplacement at higher structural levels is possibly the most important crustal differentiation mechanism. A significant control on the trace element composit
Trace Element Transport in the Continental Crust During Anatexis: The Role of Accessory Minerals
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  With National Science Foundation support, Dr. Habicht Mauche and her multi-institutional research team will examine the early development, produc
The Origin and Spread of Glaze-Painted Pottery as Seen from Tijeras Pueblo, New Mexico
A broad program of research is proposed to elucidate the geometrical structure that underlies the internal dimensions of string theory, and to overcome key obstacles to extracting 4D particle physics from this geometry. The two main areas that
String compactivication, generalized geometry and 4D physics
This Small Business Innovation Research Phase I research project w ill advance the state-of -the-art in underwater bridge inspection through development of novel long range ultrasonic technology (LRUT). The objective of this project is to deter
Submerged Bridge Pile Inspection Technology
Solarity is a start-up company located in the Innovation Park at Penn State that is focusing on manufacturable ways to make solar cells more efficient and less expensive. We have patented a novel architecture for solar cells which employs later
Solar Cell Lateral Collection Feasibility Study
Semiconductor and Related Device Manufacturing
This Small Business Innovation Research Phase I project is an innovative route to produce liquid fuels from biomass. The process will convert biomass, including lignocellulosic biomass, to liquid fuels, with three key steps. First, a synthetic
Conversion of biomass by catalytic hydrothermal gasification, bromination, and catalytic coupling
This Small Business Innovation Research Phase I project is aimed at the development of a new consolidated bioprocess to generate hydrogen from inexpensive cellulosic biomass in a single bioelectrochemical reactor. Demand for hydrogen is increas
SBIR Phase I: A Consolidated Bioprocess to Generate Hydrogen from Cellulosic Biomass
This Small Business Innovation Research Phase I project aims to develop platform clostridia strains suitable for industrial scale alcohol production from renewable feedstocks and also to improve metabolic engineering technologies for all clostr
SBIR Phase I: Metabolic Engineering for Clostridial Biotechnology
This Small Business Innovation Research (SBIR) Phase I project focuses on enhancing combinatorial and timed release of drugs for the localized treatment of cancer. Currently there are few solutions for localized elimination of tumor cells follo
SBIR Phase I: Combinatorial, controlled, and timed release of parylene encapsulated anti-cancer therapeutics
The project objective of the first phase SBIR grant is to complete a detailed architecture of specification of the VFP control framework, definition of processing engines required for programmable WiMAX/LTE processor, and to evaluate the feasib
Virtual Flow Pipelining Based Radio Communication Chip Architecture
This Small Business Innovation Research Phase I project seeks to determine the feasibility of a multispectral imaging technology, to provide real time beef tenderness prediction. The hypothesis is that it is possible to predict the tenderness o
SBIR Phase I: A multispectral system for real-time prediction of beef tenderness
This SBIR Phase I project seeks to demonstrate feasibility of a software tool employing advanced search algorithms applied to antenna design and optimization.  Current methods of designing and optimizing antennas by hand are time and labor inte
SBIR Phase I: A Search Engine for Antenna Design
The PI will develop algorithms for treating solutions of singular polynomial systems. The implementation of these hybrid symbolic-numerical methods will provide a broad research community with software whose capabilities go beyond solving regul
Algorithms and Software for Singular Polynomial Systems
The immersed boundary method is a popular numerical scheme to simulate problems problems of fluid-structure interaction. Despite the popularity of the immersed boundary method, its convergence properties are poorly understood. The goal of this
A Theoretical and Algorithmic Study of the Immersed Boundary Method
Significant increases in application complexity demand processing requirements that exceed the performance achievable by current processors using software only implementations. For example, recent multimedia standards, such as JPEG2000, have si
CSR: Small: Data-Adaptable Reconfigurable Embedded Systems (DARES)
This project is motivated by the principal investigator's research on modeling the electrical wave propagation in the heart, for which a system of variable coefficient and anisotropic elliptic-parabolic partial differential equations (PDEs) mus
Adaptive Kernel-free Boundary Integral Method for Elliptic PDEs
This research program is motivated by the recognition that the volume of sensor data is expected to overwhelm even the enormous performance improvements in silicon technology expressed by Moore's Law. The focus is the development of a low-compl
CIF: Small: Collaborative Research: Signal Design for Low-Complexity Active Sensing
Large-scale hosting infrastructures have become important platforms for many real-world systems such as cloud computing, virtual computing lab, enterprise data centers, and web hosting services. However, system administrators are often overwhel
CSR: Small: Online System Anomaly Prediction and Diagnosis for Large-Scale Hosting Infrastructures
The project investigates statistical software analysis, which infers relationships among program components by using statistical properties derived from multiple program executions. To motivate statistical techniques, it is useful to draw analo
SHF: Small: Statistical Analysis of Software
III: Small: Exlporing Data in Multiclustering Views
This project develops techniques for increasing energy-efficiency of modern data centers with performance constraints. Both computing and cooling energy are considered. According to the U.S. Environmental Protection Agency, data centers in the
CSR: Small: Green Farms: Towards a Stable Energy Optimization Architecture for Data Centers
Highway N-91, Leigh to Colfax-Dodge County Line
Wireless networks operate under hostile conditions and often exhibit multi-scale stochastic dynamics. In such dynamic environments, network algorithms for quality of services (QoS) provisioning hinge heavily on state information exchange, and n
NeTS: Small: The Impact of Message Passing Complexity on QoS Provisioning in Stochastic Wireless Networks
The goal of this proposal is to devise and implement a scalable virtual machine that includes scalable garbage collectors, profilers and just-intime (JIT) compilers. As hardware vendors deliver chip multiprocessors (CMPs) as the next-generation
CSR: Small: Scalable Applications Start with Scalable Virtual Machine Services
Archaeologists have long looked to Beringia, the region encompassing Alaska and far northeastern Siberia, for clues about the origins of the first Americans and spread of humans into the Arctic. The traditional view holds that humans first migr
Collaborative Research: What is the Nenana Complex? New Excavations at the Late-Pleistocene Owl Ridge Site, Central Alaska
CALIFORNIA STATE UNIVERSITY LONG BEACH FOUNDATION
A team of archaeologists and geologists at the Institute for Integrated Research in Materials, Environments, and Societies (IIRMES), California State University–Long Beach will use NSF funding to support research on ancient technology, econom
Expanding Opportunities for Collaborative Archaeometry Research at IIRMES, CSULB
This project takes a fresh look at the evolutionary origin of cartilaginous fishes: sharks, rays, and the less well-known chimaeras. Sharks and their relatives tend to be presented as primitive and/or supremely adapted predators, although popul
EARLY SHARKS:  THE BASAL BRANCHING PATTERN AND TIME-SCALE OF CHONDRICHTHYAN PHYLOGENY
Vision/Summary of Proposed Partnership:  The vision is to unite business development resources in the Kansas City region with colleges and universities to develop a technology commercialization process that maximizes the ability of institutions
From Whiteboard to Boardroom (W2B): Creating Innovation Infrastructure in Institutions with Modest R&D Funding
The gases in the upper troposphere and lower stratosphere (UT/LS) have a significant effect on the chemical and radiative budgets of the global atmosphere, crucial to understanding climate change. To understand the chemical makeup of the UT/LS
Deep Convective Transport to the Upper-Troposphere/Lower-Strasophere
A fundamental issue in studying biodiversity is understanding the relationship between species. This is approached by developing trees  that describe the relationships and facilitate their study, the field of phylogenetics. When such trees are
(ARRA) Collaborative research: estimating species trees with population genetic approaches: working towards a new phylogenetic paradigm for 21st century phylogenetics
A fundamental issue in studying biodiversity is understanding the relationship between species. This is approached by developing trees that describe the relationships and facilitate their study, the field of phylogenetics. When such trees are d
COLLABORATIVE RESEARCH: Estimating Species Trees with Population Genetic Approaches: Working Towards a New Phylogenetic Paradigm for 21st Century Phylogenetics
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  A request is made to fund additional and back-up instrumentation on the R/V Thomas Thompson, a 274? general purpose Global research vessel and th
Because climate and water are intimately linked in deserts, desert streams are well suited for observing consequences of both natural climate variability and human-caused climate change. Here, researchers propose to study how stream ecosystem s
LTREB: Multi-scale effects of climate variability and change on hydrologic regimes, ecosystem function, and community structure in a desert stream and its catchment
Intellectual Merit: The objective of this research is to understand the mechanisms of charge separation and recombination in photosynthetic reaction centers (RCs) and the higher-order organization of photosynthetic membranes.  This phase of the
Mechanism and Macromolecular Organization in Photosynthetic Reaction Centers
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).The development of animals begins with fertilization, the interaction between two specialized cells, the sperm and egg. The process requires exquis
Developmental Genetic Analysis of Fertilization Pathways
Some bacteria can enter a nongrowing 'persister' state that allows them to survive antibiotics and other treatments that normally kill them. By suspending growth, they may also free resources for their genetically identical clonemates.  Most sp
Evolution of persistence in the model bacterium, Sinorhizobium
Causal inference is the central goal of most social science research. In recent years, empirical researchers are increasingly relying on experiments in order to improve the validity of causal conclusions. At the same time, the methodological li
Statistical Analysis of Causal Mechanisms: Identification, Inference, and Sensitivity Analysis
Why are there so many kinds of animals? Does evolutionary diversification tend to follow a similar trajectory in different groups of animals? Our work addresses both of these questions using an integrated analysis of DNA sequence data, laborato
Collaborative Research: Layers of Adaptive Radiation in Anolis Lizards: Investigation of Previously Unexplored Ecological and Taxonomic Diversity
Biogeography is the study of the spatial distribution of species and ecosystems. While the biogeography of natural ecosystems is relatively well understood, we have a poor understanding of spatial patterns of plants in cities. Both the physical
Collaborative research: Toward a biogeography of urban forests
Intellectual Merit: Dispersal is a critically important process for shaping ecological communities and ecosystems and is increasingly receiving attention in ecology and conservation biology as landscapes and the movement pathways of organisms a
COLLABORATIVE RESEARCH: HOW STRUCTURAL HETEROGENEITY AND CONNECTIVITY OF LANDSCAPES AFFECT WIND DISP
The proposed research is directed towards the preparation of a Preliminary Design Report for an NSF Major Research Equipment and Facility Construction (MREFC) project: The Deep Underground Science and Engineering Laboratory (DUSEL) at the forme
ARRA: COLLABORATIVE RESEARCH: DEVELOPMENT OF A FRACTURE PROCESSES FACILITY AT DUSEL HOMESTAKE
The project will provide novel insight into how aerodynamics, skeletal motion, neuromuscular control and muscle mechanicl work and power integrate during drastically different form of vertebrate locomotion.  Furthermore, this data, for the very
Ontogeny of Avian Locomotion:  Aerodynamics, Skeletal Kinematics, and Neuromuscular Control.
This financial assistance was awarded in support of The Reinvestment Fund's (TRF) Comprehensive Business Plan. Specifically, this award supports TRF, a high-performing community development financial institution, in its financing of affordable
Founded in 1997, The Progress Fund (TPF) is a vigorous non-profit corporation that creates economic opportunity by lending needed capital and providing entrepreneurial coaching to underserved small businesses in Appalachia (39 rural counties in
Given a significant spike in market demand for our loan products, Leviticus Fund used this Recovery Act award to increase its lending capacity for community development in low-income areas in New York, New Jersey and Connecticut. Specifically L
Lending in Support of Child Care and Affordable Housing
MIDWEST MINNESOTA COMMUNITY DEVELOPMENT CORP
Midwest Minnesota Community Development Corporation is currently using the awarded FY 2009 money provided by the Recovery Act to expand an in-house loan pool for home mortgages by providing low-cost credit to high risk populations.  Our target
Financial assistance to expand an in-house loan pool for first and second home mortgages in rural Minnesota
This $2M grant from the US Department of Treasury's Community Development Financial Institutions Fund will help the Vermont Community Loan Fund transform lower-income Vermonters' lives as we provide access to capital for affordable housing, sma
The National Community Investment Fund (NCIF) received a $2.0 million Financial Assistance (FA)/ American Recovery and Reinvestment Act (ARRA) award for the purpose of making strategic, high-impact debt & equity investments in community develop
Investing in Community Development Banks
This Award allows Community and Shelter Assistance Corporation's (CASA) Community Development Financial Institution (CDFI) the ability to provide secondary financing to low income, cooperatively owned manufactured housing parks. Manufactured Ho
Community and Shelter Assistance Corp. Community Development Financial Institution
This $2 million Financial Assistance Award provided us enough capital to supplement our Allowance for Loan and Lease Losses (ALLL).  While the award recipient was Bancorp, we delivered our products and services through our subsidiary, the Bank.
RUTLAND WEST NEIGHBORHOOD HOUSING SERVICES, INC
The Home Rehabilitation and Homebuyer Lending Program will provide Home Improvement Loans that are fixed-rate, low interest loans for private homeowners who are not able to access conventional financing to make necessary repairs, energy efficie
Home Rehabilitation and Homebuyer Lending Program
FA Component, CDFI Program award will be entirely directed towards activities that are critical to the successful implementation of Phase Two of the Community Stabilization & Capitalization Initiative (CSCI).
FA Component , CDFI Program, Affordable Housing
The White Earth Investment Initiative began in 2002 and became a certified Community Development Financial Institution in 2007.  It pairs lending with development services on the White Earth Reservation in order to build assets for individual a
Genetic, geographic and ecological processes can isolate related plants resulting in the evolution of new species. Reproductive isolation is a very important component of this process that determines whether closely related plants are sexually
Prezygotic Interspecific Reproductive Barriers in Nicotiana
The complete abstract for this award is available in Research.gov at : www.research.gov. Objectives: The objective of this research is to use single-molecule techniques of atomic force (single-molecule antibody recognition force microscopy) and
Collaborative Research:  Using Single-Molecule Force and Fluorescence Microscopy to Elucidate the Molecular Mechanism of Bioinspired Magnetite Synthesis in Magnetotactic Bacteria
This interdisciplinary study combines efforts from mathematicians and ecologists to develop more suitable models and modeling approaches that address issues of interest to both ecologists and resource managers. The specific objectives of this p
Collaborative Research: Plant-herbivore interactions mediated by toxin-determined functional response
The concept of a neural network is central to the way we think about the brain, and has permeated research in many disciplines. It is widely believed that the activity of a population of neurons emerges from the dynamics of neural circuits. On
Stimulus Representation and Spontaneous Activity in Recurrent Networks
Although geography is an organizing feature of K to 12 education, the U.S. lacks an integrated database that describes student populations living in school attendance boundaries. The lack of a spatial database of school attendance boundaries ha
Collaborative Proposal: School Attendance Boundary Information System (SABINS) Data Project
'This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).'  This grant supports a program of research to explore the underlying principles that guide individual attitudes about aggressive interrogation.
RUI: Psychological Motives Underlying Attitudes toward Aggressive Interrogation.
This research will draw on more than 90,000 criminal cases that have yielded a conviction in U.S. urban courts between 1990 and 2008 to explore changes over time in the magnitude of racial and ethnic differences in the probability of incarcerat
A Temporal and Spatial Analysis of Gender, Race, and Ethnic Disparities in the Probability of Incarceration
This research investigates the ways in which claims to sovereignty in the Arctic rely on territorial imaginaries: explicit and assumed conceptualizations of a place’s elemental nature, its geophysical properties, and its geographical location
Collaborative Research: Territorial Imaginaries and Arctic Sovereignty Claims
Shallow marine carbonate rocks that are deposited at continental margins are subjected to intense deformation at convergent plate boundaries, and a growing body of evidence indicates that these carbonate rocks are entrained in subduction zones
Experimental and Natural Deformation of Magnesian Carbonates
The direction and intensity of the Earth's magnetic field varies in both time and space. As volcanic rocks cool they record a snapshot of the field and through careful laboratory experiments the evolution of the magnetic field during Earth's ap
Linking Rock Magnetic Properties to the Performance of Paleointensity Techniques
Synthetic Approaches to Endohedral Complexes and Highly Functional Derivatives of Fullerene C60
SYNTHETIC APPROACHES TO ENDOHEDRAL COMPLEXES AND HIGHLY FUNCTIONAL DERIVATIVES OF FULLERENE C60
This Small Business Innovation Research (SBIR) Phase I project is to demonstrate a novel technique for producing freestanding GaN wafers and substrates.  Low-cost, high-quality GaN substrates are important for volume production of high-brightne
A Novel Approach for Production of Freestanding GaN Wafers for III-Nitride Light Emitters and Detectors
Selective Laser Sintering of Bioglass Scaffolds for Bone Tissue Engineering
Glass Product Manufacturing Made of Purchased Glass
SBIR Phase I: Bioadhesive Construct to Augment Rotator Cuff Repair
Label-free biosensor systems utilizing Surface Plasmon Resonance (SPR) to detect molecular interactions are an important tool in basic research and drug development.  SPR biosensors require a metal-coated surface, and gold is currently the most
SBIR Phase I: A metal-free surface for label-free array detection
SBIR Phase I: Heat Spreader Using Nanofluid Oscillating Heat Pipes
This Small Business Innovation Research Phase I research proposal addresses synergistic integration of navigation and environmental sensing instruments on manned or autonomous ground or air vehicles to both improve information registration accu
The sensors under development have the potential to dramatically improve the sensing capabilities of infrared remote sensors used for satellite-based global mapping, homeland security and military applications, which currently represent a $1 b
Light-channeling Metamaterials for Polarimetric Sensing
Metal atoms will be chemically etched from a metal carbide lattice, leaving only carbon, the pore size of which can be tuned with Angstrom precision by varying the carbide precursor or etching conditions. While the use of a metal carbide lattic
High Performance Electrochemical Capacitor Using Carbide-Derived Carbon Nanomaterial Electrodes
SBIR Phase I: Large-Scale Production of Monodisperse Single-Walled Carbon Nanotubes
This Small Business Innovation Research Phase I project proposes to develop a set of novel, versatile measurement tools for use during fermentation and scale-up in metabolic engineering. The tools will be based on the production of odorants and
SBIR Phase I: Volatile gene expression reporters for use during fermentation
In this Phase I SBIR program, RK Composites, Inc. (RKCI) and its partners is developing intelligent sensors for structural state sensing. For this phase I program, the RKCI-led team will demonstrate the feasibility of a successful intelligent s
Intelligent Sensors for Health Management
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  This Small Business Innovation Research (SBIR) Phase I project will combine the capabilities of Picarro?s WS-CRDS (wavelength-scanned cavity ring
A Simple, Robust, Low Cost Tool to Quantify Stable Isotopes in Organic Molecules: Enabling Easy Access to Compound Source, Pathway, and Biokinetic Studies
This Small Business Innovation Research Phase I research project will develop underlying technologies that will enable Unmanned Air Vehicles (UAV) to navigate inside houses and buildings. This technology, applied to emergency response situation
SBIR Phase I: An Indoor/Outdoor Robotic Air Vehicle for Emergency Response
SBIR Phase I:  Next generation optochemical sensors for detection of growing mold  Mold contamination in buildings presents significant health  and economic problems.There were about $8 billion in mold-related damage claims made under property
SBIR Phase I:  Next generation optochemical sensors for detection of growing mold
The main objective of the project was to develop anisotropic hard magnetic nanoparticles to be consolidated by screen-printing into permanent magnet structures with dimensions that cover the current dimensional gap between the permanent magnet
Synthesis of Hard Magnetic Nanoparticles and Fabrication of Micromagnets for MEMS Applications
All Other Miscellaneous General Purpose Machinery Manufacturing
This Small Business Innovation Research Phase I project seeks to develop advanced control technologies for improving the overall cost-effectiveness of small-scale vertical axis wind turbines. Most commercial wind turbines operate at energy effi
Advanced Control and Estimation for Cooperative Vertical Axis Wind Turbines
Highway Infrastructure Investment - Highway resurfacing - From funding available for use in any Area (flexible)
Computing architectures are increasingly parallel, most relying on multi-core microprocessors. Trends are also towards increased heterogeneity, with systems combining diverse components ranging from multiple microprocessors, field-programmable
CSR: Small:  Elastic Computing - An Enabling Tecnology for Transparent, Portable, and Adaptive Multi-Core Heterogeneous Computing
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).The Sound Citizen Apprenticeship Program is a pilot partnership between the University of Washington's School of Oceanography, the UW Institute for
OEDG: Sound Citizen Science Apprenticeship Program for Minority Youth (Track 1)
1503 Boat St., Rm 104 Ocean Teaching Building
The overall purpose of this project, Diversity Enhancement of Geosciences through Research Experiences (DEGReE):  Mentoring African Americans through Research and Professional Development (Track 1), is to increase the number of African-American
Diversity Enhancement of Geosciences through Research Experiences (DEGReE): Mentoring African Americans through Research and Professional Development (Track1)
Department of Geosciences, Mississippi State University
0-1 Semidefinite Programming (0-1 SDP) is a new optimization model that covers several classes of challenging nonlinear integer programming problems. 0-1 SDPs arise frequently from numerous applications in various domains such as learning, comm
0-1 Semidefinite Programming: Modeling Theoretical Foundation Resolution and Applications
'SHF: Small: Analyzing and Modeling Natural Language Usage in Software to Improve Software Maintenance Tools'  Large scale software nowadays -- hard to maintain and modify and keep up to date. There is a dire need for automated support for soft
SHF:SMALL: ANALYZING AND MODELING NATURAL LANGUAGE USAGE IN SOFTWARE TO IMPROVE SOFTWARE MAINTENANCE TOOLS.
Using Ternary Content Addressable Memories (TCAMs) to perform high-speed packet classification has become the de facto standard in industry. Despite their high speed, TCAMs have limitations of high cost, small capacity, large power consumption,
NeTS:Small:Algorithmic Approaches to Optimizing Hardware-Based Packet Classification Systems via Equivalent Transformation
Cheap commercial off-the-shelf wireless devices are being increasingly deployed for performance-sensitive applications such as patient monitoring with body sensors and home networking for multimedia and gaming. However, wireless communications
NeTS:Small:Collaborative Research:Holistic Transparent Performance Assurance within the Crowded Spectrum
Many studies have shown that human mistakes are an important source of system failures. Further, repairing mistakes is often time consuming, leading to high unavailability. In this project, we will explore a novel approach to dealing with human
CSR:Small: Operator Proof Systems Management
Division of Computer and Communication Foundations (CCF) NSF program : Compilers Automatic and Manual Debugging Support for Massively Parallel Programs.  The research funded by this award targets the difficult problem of how to debug programs r
SHF: Small: Ant: Automatic and Manual Debugging Support for Massively Parallel Programs
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).   The project will develop efficient mechanisms for deploying and managing wireless self-organizing networks (WSONs). These networks are able to m
Collaborative proposal: A Geometric        Computational Approach to Efficiently Deploy and Manage        Self-Organizing Wireless Networks
In 2006, the NSF EPSCoR states of Maine, New Hampshire, Rhode Island, Vermont and Delaware (VT, NH, ME, RI DE) launched an initiative that we have recently renamed the North East Cyberinfrastructure Consortium (NECC, formerly NE Network Initiat
Collaborative Research: North East Cyberinfrastructure Consortium
With National Science Foundation support, Dr. Maria Nieves Zedeno and a team of colleagues and Blackfeet collaborators will conduct two seasons of archaeological fieldwork on the US northwestern Plains. Together they will examine the relationsh
The Complex Organization of Communal Bison Hunting: Revisiting the Late Prehistory of the Northern Plains
Fungi in the groups Harpellales and Asellariales spend their entire lives in the guts of insects; they cannot grow independently. They may be parasites or may be mutualists that live in harmony with their hosts. The fungal-host associations can
Collaborative Research: REVSYS: RUI: Phylogenetic and Revisionary Systematics of early-diverging, ecologically unique clades of fungi, Harpellales and Asellariales
The North East Cyberinfrastructure Consortium was formed to develop resilient, high-bandwidth connectivity between research and academic institutions in ME, RI, NH, VT and DE.  We have initiated two related collaborative efforts to identify and
Collaborative Research: Northeast Cyberinfrastructure Consortium
Understanding how species form (speciation) is a fundamental area of study in the fields of taxonomy and evolution, and is the basis of all studies in comparative biology. However, most current theories of speciation are based upon organisms th
Collaborative research: Estimating speciation/reticulation boundaries in asexual Alternaria: A genomics approach
Detailed information on protein dynamics at an atomic level and its thermodynamic implications is of fundamental biophysical importance for understanding protein stability and function.  The only currently available tools to probe such informat
Dynamics and Thermodynamics of Proteins by NMR and Computation
In the United States, crop loss due to infection by plant pathogens, including plant viruses, has been estimated to exceed thirty billion dollars per year. In the environment, the genomes of plant viruses, as well as small, virus-associated (su
Collaborative research: Identification of cis-acting sequence and structural elements required for replication of a viral RNA
This collaborative proposal addresses the genetic basis of post-pollination prezygotic reproductive isolation between sympatric sister species of yellow monkeyflowers.  Towards the goal of identifying the molecular genetic basis of conspecific
COLLABORATIVE PROPOSAL:  Evolutionary Genetics of Pollen Competition in Yellow Monkeyflowers.
One of the major unanswered patterns in ecology is the latitudinal gradient of species diversity from the tropics to the poles. This project will develop a comprehensive explanation for this and related patterns in the distribution and abundanc
ARRA-OPUS: Global Biodiversity: Synthesis of Ecology and Evolution
Lakes, estuaries, and coastal marine waters throughout the world have been degraded by over-enrichment with plant nutrients such as nitrogen (N) that cause algal blooms, and eventually deplete dissolved oxygen. Nitrogen exports to aquatic ecosy
Collaborative Research: The missing anthropogenic N--assessing denitrification at the watershed
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  Red algae are among the dominant photosynthetic organisms in the sea. Many are leafy seaweeds, but a large number grow as crust-like pavements on
Systematics of the Peyssonneliaceae (Peyssonneliales), a family of crustose marine red algae
Broad to fine scale phylogenetic pattern and character evolution in ruellieae (Acanthaceae)
Broad to fine scale phylogenetic pattern and character evolution in Reullieae (Acanthaceae)
The Yoder laboratory studies genetic control of events that shape animal form. Patterning animal bodies requires integration of genetic signals that converge on otherwise similarly fated parts of the developing body conferring unique identities
Hox regulation of wingless expression sculpts morphogenesis of the adult Drosophila abdomen
CEIBA HOUSING & ECONOMIC DEVELOPMENT CORPORATION
The CDFI Awardee received financial assistance of $500,000.00 for lending and $100,000.00 for operational expenses. Awardee attempts to expand its financial products to include products specifically designed for its target market (disadvantaged
Financial Assistance Component of CDFI Program
Lowcountry Housing Trust (LHT) is a non-profit regional housing finance entity established in 2004 and certified as a CDFI in 2007. LHT's mission is to provide financing and capital to assist nonprofits, government entities and private develope
MOUNTAIN ASSOCIATION FOR COMMUNITY ECONOMIC DEVELOPMENT INC
The Mountain Association for Community Economic Development works to create wealth for people who need it most in Kentucky and Central Appalachia while protecting the places where they live. Central Appalachia faces many daunting challenges inc
Community Development Financial Institution - Financial Assistance. This award will be used to provide affordable housing for people in Maine.
Pre-Development and Rehab Financing for Affordable Housing Preservation
The Recovery Act funding capitalized the lending pool for the Montana HomeOwnership Network (NeighborWorks Montana). The loans financed individual loans, primarily written as second mortgages to pay for down payment and closing costs for low-in
Montana statewide lending project to support affordable housing
Understanding how genes and environment act through complex biological networks to influence social behavior is a fundamental challenge in biology. This proposal addresses long-duration behavioral 'states' in honey bee workers, which are known
A Systems Approach To Brain and Behavioral State in the Honey Bee
Invasive species are a large and growing threat to ecosystem function, biodiversity and even human health. However, the traits that enable some species to expand their ranges and become pests remain understudied. The focus of the project is to
Physiological mediation of vertebrate invasions
Loss and Rescue of Regeneration in Naidine Annelids.  Animals vary tremendously in their ability to replace lost body parts. While some animals, such as humans, cannot re-grow most body parts, others, such as some segmented worms, can re-grow a
Loss and rescue of regeneration in naidine annelids
Who first populated the Americas and when? Where did they come from and how did they get here? What was their lifeway like? These are not trivial questions since the Americas, comprising 24% of the Earth's land surface, were the last major area
? Investigating the Cultural Antecedents of Clovis at the Gualt Site, Texas
Understanding workers' responses to incentives is critical to enhancing firm productivity as well as the overall efficiency of an economy.  The projects in this proposal involve conducting economic experiments to provide a better understanding
Incentives in the Workplace: An Experimental Examination of How Wage Differences Across Time and Among Peers Affect Productivity and Self-Selection
Ribotoxins kill cells by endonucleotically cleaving essential RNAs involved in protein translation (rRNAs, tRNAs, and mRNAs). We have identified a novel bacterial RNA repair system that neutralizes the effect of ribotoxins. This unique RNA repa
Biochemical and Structural Analysis of RNA Methylation in RNA Repair
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). Whales are mammals that evolved from land to sea during the Eocene epoch of geological time. The transition was made by Archaeoceti or archaic wh
TRANSITION TO TAIL-POWERED SWIMMING IN THE FIRST FULLY AQUATIC WHALES OF EOCENE TETHYS (EGYPT)
Conflicts continue to rage in the Levant, South Asia, and elsewhere. Governmental, nongovernmental, and intergovernmental organizations are seeking a technology that will help them anticipate the outbreak of violence. Some progress has been mad
Collaborative Research: Development of a Technology for Real Time Ex Ante Foecasting of Intra and International Conflict and Cooperation
Research on economic sanctions has advanced a great deal in recent years and there has been an impressive relationship between theory and evidence. Recent empirical work has led to the development of theoretical questions that cannot be answere
Collaborative Research: The Threat and Imposition of Economic Sanctions
During the late 1700s, colonial Mexicans and Peruvians sued each other more than they ever before had in 300 years of Spanish control. Spanish culture is widely described as legalistic and litigious. Yet, in Spain, there was little change in ci
Taking Tyrants to Court: Civil Litigation in The Spanish Empire
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  The premise of this research is that a society's prosperity hinges in part on property being sufficiently secure from theft so that investing in
Property Rights, Collective Action, and Public Choice: An Experimental Study
Food, Agriculture & Nutrition, General/Other
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). To predict present and future rapid coastal evolution, we must first reconstruct the long-term rates of local-relative sea-level rise in response
Holocene Sea-level Change in the Caribbean: Implications for Geophysical Modeling and Ocean-Climate Interactions
An increase in Earth surface oxygen levels has long been invoked as a driver of biological innovation at the end of the Neoproterozoic Era (1000 to ~541 million years ago), when diverse macroscopic life, including animals, first flourished. Rec
Collaborative Research: Ocean Oxidation and the Biosphere During Neoproterozoic Glaciation
The Virtual Research Data Center at Cornell University has been a successful research support tool for users of many of the Census Bureau large-scale confidential data products including, but not limited to, those that are accessible via the Ce
I. Intellectual Merit. The nature of price setting by firms is central to many important questions in macroeconomics. Over the last few years, research on firm price setting has been transformed by the increased availability of micro price data
Price Adjustment, Exchange Rate Policy and Monetary Models
A number of times during life's history, biodiversity was decimated by mass extinctions that wiped out a large proportion of the Earth's species. The five largest mass extinctions of the prehistoric world are known as the 'Big Five' (the dinosa
Paleoecologic Gradient Analysis of the Frasnian/Famennian Extinction and Recovery
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).   A new flow cytometer, a cell counter, and a phase-contrast microscope with digital camera are being used to help advance the cellular and molecu
MRI: Acquisition of flow cytometric, cell quantification and imaging equipment for use in functional studies of the human junction protein, claudin-3.
This research will provide an excellent opportunity to evaluate how previous flume research or field studies of small channels, upon which much of what is known about sediment transport and related asects of fluvial processes is based, scale up
Sediment routing in gravel-bed rivers following dam removal.
Collaborative Research: Ocean Oxidation and the Biosphere during Neoproterozoic Glaciation  Susannah Porter (Lead Principal Investigator); EAR-0922305 University of California Santa Barbara  Matthew Hurtgen; EAR-0921913 Northwestern University
COLLABORATIVE RESEARCH: Ocean Oxidation and the Biosphere During Neoproterozoic Glaciation
The underlying genetic basis behind anatomical, physiological, or behavioral adaptations arising during the evolution of humans and great apes (hominids) remains largely unknown. Observable change may come from changes to protein-coding genes,
Molecular Evolution of Hominoid Proteins
Studies of exotic nuclei (those with a large excess of neutrons) are a top priority to address a number of outstanding nuclear physics questions. These include measurements to explore changes of the nuclear structure in nuclei far from stabilit
MRI-Consortium: Development of a Neutron Detector Array by Undergraduate Research Students for Studies of Exotic Nuclei
From the 1960s through the 1980s, social scientists conducted a number of studies of the role of large corporations in American political life. This work slowed to a trickle in the 1990s. The environment within which American corporations opera
The Changing Nature of the American Corporate Elite, 1960-2009
In this project, the applicants propose the development of a novel chemical analysis technology. Analysis of chemical species has been important to many technological advances. Current technologies rely on adsorption spectroscopy, inductively c
MRI: Development of a Controllable optical emission spectroscopy diagnostic system for use in atomic and molecular sciences
Studying activity of the human brain non-invasively is a major scientific challenge, yet it is essential for enhancing our understanding of the neural bases of action, emotion, and thought. A major technological advancement in studying the neur
MRI: Acquisition of a 3-Tesla Magnetic Resonance Imaging (MRI)
Funds for the purchase of an advanced ultrafast laser system for nonlinear spectroscopy are requested. The system that specified is a Spectra-Physics Spitfire Pro 40F-5W ultrafast laser system. The pulse length of the fundamental output of the
MRI: Acquisition of a High Pulse Energy ultrafast Laser System for Interdisciplinary Research
The intellectual merit is based on our research accomplishments. We have a demonstrated record of managing high-quality undergraduate research laboratories, regularly publishing papers in peer-reviewed journals with our undergraduate collaborat
MRI: Acquisition of a 400-MHz NMR Spectrometer to Support Undergraduate Research and Chemical Education at Towson University
The project has focused on the key development areas for the Inner Magnet as outlined below and good progress has been made with a number of these tasks.  The work to-date has continued to be funded from other sources and has addressed issues o
MRI: Development of a 32 Tesla all Superconducting Magnet Using YBaCu307-X Coated Conductor
MRI: Development of a Ground-based Interferometric Radar
MRI: Development of a Ground-based Interferometric Radar for Infrastructure and Natural Hazards Applications
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  We will acquire an ultraviolet laser for novel quantum imaging experiments at Colgate University. The grant will support and enhance the infrastr
MRI: Acquisition of an Ultraviolet Laser for Quantum Imaging
The development of a low temperature scanning tunneling microscope with spin-polarized and spectroscopic capabilities is proposed (SP-STM). While a handful of similar instruments are operating in Europe and Japan, so far there are only two in t
MRI: Development of a Spin-polarized Scanning Tunneling Microscope for Nanomagnetism Studies
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  This Major Research Instrumentation (MRI) award funds the acquisition of a laser scanning confocal microscope with spectral detection at Colgate
MRI: Acquisition of a laser-scanning confocal microscope for multi-disciplinary research at Colgate University
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).    With this award from the Major Research Instrumentation (MRI) program, Daniel M. Knauss and colleagues Stephen G. Boyes, Steven F. Dec, Andrew
MRI: Acquisition of High-Field NMR Instrumentation for the Colorado School of Mines with Outreach to the Denver Metro Region
Analogous to the use of medical X-rays to assess human structural features and plan medical treatment, analytical laboratory X-rays are vital in determining structural information for solid samples, often leading to the rational development of
Acquisition of a Multi-Institutional, Multi-departmental, Modern X-Ray Diffraction System to Anchor a Portland Area Materials Characterization Group
This Major Research Instrumentation (MRI) award funds the acquisition of a fast protein liquid chromatography (FPLC) biomolecule purification system to support an interdisciplinary consortium of Seattle University faculty, their programs in und
MRI: Acquisition of an FPLC Chromatography System for Use in Biomolecule Purification, Protein Analysis, and Research Training at Seattle University
The proposed MRI Development project will build and test an Affordable System for Solar Irradiance Sensing and Tracking (ASSIST). ASSIST will serve as model sensor and information technology system for directly and quantitatively observing the
MRI: Development of ASSIT: Affordable System for Solar Irradiance and Tracking
For two decades now, virtually all systematic analysis of the contemporary Supreme Court and its members has relied on Harold J. Spaeth's U.S. Supreme Court Judicial Database. This holds for research conducted by social scientists and, increasi
Collaborative Research: Updating the U.S. Supreme Court Judicial Database
ECOLOGICAL SOCIETY OF AMERICA, INCORPORATED
Diversity program in the field of Ecology
'The ability of an animal to maneuver can determine its success at avoiding predators, catching food, and other fundamental behaviors that define the margin between life and death. Most research on the biomechanics of animal motion has concern
Collaborative Research: Computational Analysis of Maneuvering Flight
The diversity and pervasiveness of bacterial partnerships with animals is only now being fully appreciated. In many marine environments these symbioses play critical roles in sustaining high productivity. This project concerns symbioses between
MSB: Collaborative: Symbiont Separation and Investigation of the Novel Heterotrophic Osedax Symbiosis Using Comparative Genomics
This Small Business Innovation Research (SBIR) Phase II research project seeks to develop a radically new type of mobile robot. Most of today's robots rely on wheels to move from one location to another but the proposed Tri-Sphere robot moves b
Combining Mobility and Manipulation in a Tri-Sphere Robot
This Small Business Technology Transfer (STTR) Phase II project will develop and apply a principled design methodology to confront the serious problems associated with deep sub-micron, system-on-chip (SoC) integrated-circuit designs.  The suppo
STTR Phase II:  Blended Integrated Circuit Systems
This Small Business Innovation Research Phase II project will result in the development of a novel semiconductor growth technique to produce low dislocation density III-nitride AlInGaN substrate materials for high efficiency deep UVLEDs and ele
Dopamine (DA) is an important and universal modulator of motor control, but neuroscientists have yet to determine precisely how DA-containing neurons and their targeted circuitry choreograph specific locomotor programs. This has been an especia
Collaborative Research: The Neurobiology of dopamine in the leech and the modulation of locomotor behaviors
The overall purpose of the award is to further extend and ultimately to commercialize our phase I efforts to develop a novel and fruitful approach to natural product drug discovery. Our unique technology encompasses screening environmental DNA
STTR Phase II: An Advanced Antibiotic Screen of Marine Environmental DNA through a Metabolically Engineered E. coli Strain
Cooper and Kagel (2005, in press) found that strategic play in two person teams beat the truth wins benchmark by wide margins and that teams display impressive levels of cross-game learning.  Cooper, Kagel and Mayefsky (2008) study the effects
Collaborative Research: Experimental Studies On Group Decision Making In Strategic Environments
FY2009 COLA/QI. Funds provided staff with COLA increases which allowed KCSL to provide market competitive wage rates. QI funding made it possible to change 30 home-based slots to center based slots in Liberal, Kansas.
Award Title = FY2009 ARRA COLA/QI.  Award Description = Head Start and Early Head Start Cost of Living Adjustment and Quality Improvement.  Overall Purpose of the Award = fund cost of living salary increases, increased operating costs, addition
DELTA AREA ECONOMIC OPPORTUNITY CORPORATION
FY 2009 ARRA/COLA, Quality Improvement. SE  AWARD DESCRIPTION The Head Start program provides comprehensive child development services to economically disadvantaged children and families, with a special focus on helping preschoolers develop the
COMMUNITY ACTION PARTNERSHIP OF GREATER ST. JOSEPH
The ARRA Cost of Living Adjustment (COLA) and Quality Improvement Funding enhances the early childhood education and family services provided to 483 children in Andrew, Buchanan, Clinton, and Dekalb Counties in Northwest Missouri.  Specificiall
ARRA Cost of Living Adjustment and Quality Improvement Funding
SOUTHEAST NEBRASKA COMMUNITY ACTION COUNCIL, INC.
Cola and Quality Improvement grant made available to Head Start program under the American Recovery and Reinvesmtent Act.  Awarded under Can No. 2009 R022
Head Start Quality Improvement and 1.84% COLA Funding:  COLA funding will be used to increase current Head Start staff salaries by 1.84% and to increase budgeted amounts for utilities, vehicle insurance, vehicle fule, parent activities and nutr
Head Start ARRA Expansion:  Head Start Expansion to expand 32 Head Start enrollment slots in Cowley County, Kansas. Head Start enrollment slots will be increased by 16 in Arkansas City, Kansas and 16 in Winfield, Kansas to provide an additional
Daily community support system utilizing afterschook, community watch, sat and summer program for 60 youth/families with opportunities that improve lifeskill, socioeconomi status in a community laden with drugs,gangs,crime, and violence
SOL-80, Pavement Rehab East HOV overlap section  I-80 HOV Lanes in Solano County
I-80 Corridor Bridge Painting, Construction, Interstate Bridge painting Contract No. 1
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  Thomas Keyes of Boston University is supported by a SGER award from the Theoretical and Computational Chemistry program to provide the most widel
SGER: Replica Exchange STDM for CHARMM: A Potentially Large Advance in Biophysical Computing
This project combines a theoretical and numerical study of one of the mechanisms that may initiate magnetic reconnection in a geomagnetic substorm. The general mechanism is an enhancement in the electrical resistivity of the plasma brought on
Nonlinear Theory of Anomalous Resistivity for Buneman Instability
Project AbstractThis award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). Mountain snowmelt is an essential resource to 40% of the world?s population but is threatened by warming associated with climate c
Using mesoscale climate simulations to reduce input data errors in energy balance snow hydrology models
Noble gas radionuclides provide a new and previously unexplored tool that can help distinguish the origin of the atmospheric components associated with volcanic gases. In this project led by a beginning female investigator, we aim to measure th
New Insights on Mantle Volatiles from Noble Gas Radionuclides
The Mathematics Department at UIUC aims to train stewards of the mathematical enterprise. Our programs facilitate all stages of development from prospective undergraduate math major to senior mathematician. We propose here to enhance our REGS p
EMSW21-MCTP: Research Experience for Graduate Students
Ice sheet Dynamics and Processes along the West Antarctic Continental Shelf
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). This project continues research on Triassic and Jurassic faunas from the Beardmore Glacier region of Antarctica. Research will be supported for on
COLLABORATIVE RESEARCH: New Research on the Mesozoic Vertebrate Faunas of the Beardmore Glacier Region, Antarctica
The near shore environments of the western Antarctic Peninsula (WAP) harbor extremely high densities of mesograzers (small invertebrate predators approximately 1-25 mm in length) such as benthic amphipods, as well as rich assemblages of macroal
Collaborative Research: The Chemical Ecology of Shallow-water Marine Macroalgae and Invertebrates on the Antarctic Peninsula
The Antarctic Marine Geology Research Facility (AMGRF) at Florida State University is the largest repository of Southern Ocean piston cores in the world.  The AMGRF provides numerous services to the Antarctic and Earth Science community.  This
Curation of National Antarctic Marine Sediment Collections
The paucity of conventional meteorological observations over the Antarctic continent represents a major challenge to both weather  forecasts and climate analysis. This puts a premium on the productive use of satellite data, including non-tradit
(ARRA) Collaborative research: Atmospheric data assimilation techniques for Antarctic applications
ANDRILL (ANtarctic geological DRILLing) is an international, multidisciplinary program designed to investigate Antarctica's role in Cenozoic global environmental change. After two successful drilling projects, ANDRILL proposes to move northeast
Coulman High Project: Investigating Antarctica's Role In Cenozoic Global Environmental Change
The proposal seeks funding to continue astronomical site-testing investigations at the South Pole Station using the Gattini-UV camera that will provide data on sky brightness in the Astronomical U and B bands for the very first time. The objec
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). The LISSARD project (Lake and Ice Stream Subglacial Access Research Drilling) is one of three research components of the WISSARD integrative initi
Collaborative Research: Integrative Study of Marine Ice Sheet Stability and Subglacial Life Habitats in West Antarctica-Lake and Ice Stream Subglacial Access Research Drilling (LISSARD)
Polar Experimental Network for Geospace Upper-atmosphere Investigations (PENGUIn): Interhemispheric Investigations along the 40 Degree Magnetic Meridian
With this award from the Chemistry Research Instrumentation and Facilities: Multiuser program (CRIF:MU), the Chemistry Department at the University of Rochester will acquire a matrix-assisted laser desorption/ionization time of flight (MALDI-TO
ACQUISITION OF A MATRIX-ASSISTED LASER DESORPTION/IONIZATION TIME OF FLIGHT (MALDI-TOF) MASS SPECTROMETER
With support from the Chemistry Research Instrumentation and Facilities:Multiuser program (CRIF:MU), the Department of Chemistry at the University of Texas at Arlington (UTA) will upgrade a 500 MHz nuclear magnetic resonance (NMR) spectrometer
Upgrade of NMR Facilities for Research and Teaching
COLLABORATIVE RESEARCH:  EXPLORING THE CHEMICAL REACH OF THE MADDEN-JULIAN OSCILLATION:  SATELLITE/IN-SITU DATA ANALYSIS AND CHEMISTRY/TRANSPORT MODEL
'This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).' Solar energy harvested by plants provides the energy required for the major metabolic pathways within plant tissue (e.g. photosynthesis, photore
Plant Energy Metabolism and Carbon/Nitrogen Assimilation
This proposal seeks ~$126K funding to purchase a second multi-anvil high pressure device. The current multi-anvil systems are fully booked ? and have been so for the past four years. Requested is a 1000 ton capacity, 8800 psi press with a 15' v
Upgrade of the Multi-Anvil High-Pressure Facility at Arizona State University
The focus of this project is on quantum dynamics studies of the recombination reaction of oxygen atoms (O) and molecular oxygen (O2) to form ozone (O3), in order to study the anomalously large isotopic enrichment of stratospheric ozone. A hiera
Quantum Origin of Anomalous Isotope Effects
We are using new continuous GPS and seismic data products from EarthScope facilities to investigate possible dynamic links between vertical crustal motions and lithospheric structure. We are combining PBO and PBO NUCLEUS data with GPS data from
Geodetic Expressions of Plate Boundary Zone Dynamics from EarthScope Facilities
Hormonal responses to an experience can gate how well and for how long the experience is remembered. Epinephrine (adrenaline) is one such hormonal regulator of memory strength and durability. Recent findings by the PI, using an electrophysiolog
Neuroendocrine Modulation of LTP Durability
1) Why some supercell-spawned tornadoes are particularly long-lived?  2) How environmental conditions influence tornado genesis, intensity, and longevity?  3) How capping inversions and microphysical makeup influence cold pool strength and the
Collaborative Research: Investigating Supercell/Tornado Genesis, Structure and Evolution using Observations and Numerical Models
Chromium in its hexavalent form, Cr(VI), is mobile and toxic in the environment. Reduction of Cr(VI) to the trivalent form, Cr(III), is a very important process as it renders Cr immobile and less toxic. Reduction induces stable isotope fraction
Collaborative Research: Chromium Isotopes as Redox Indicators - Oxidation and Isotopic Equilibration Experiments
Strong emotional reactions to minor provocations can be detrimental to the psychological and physical health of individuals and those around them. The psychology literature has shown that such strong reactions are not characteristic of all indi
Developing a Cognitive Control Theory of Emotion Regulation Through the Lens of Hostility, Anger, and Aggression
An increasing number of mobile users rely on wireless technologies to gain secure and uninterrupted access to network services. As the volume of data disseminated via the wireless medium rapidly expands, provision of performance, reliability, a
Career: Securing Channel Access and Availability in Multi-Channel Ad Hoc Networks
The ability of coastal wetlands to survive accelerated sea level rise is a critically important and open question.  Coastal marshes, which are dominated by the march grass Spartina alterniflora, build the land vertically (accrete) through a com
Collaborative Research:  Eco-geomorphic coupling:  Vegetation transition and sedimentary responses
This CAREER project is built on the PI's ultimate research vision to develop accessible technologies to address significant challenges limiting stem cell discovery. The significant challenge addressed is unraveling the mechanism(s) by which ste
ARRA CAREER: Dissecting the Biological Impact of Stem Cell Fusion, a Unified Plan for Stem Cell Discovery via Accessible Engineering
RESEARCH EFFORT: The attachment of dissimilar materials is a major engineering challenge because of the high levels of localized stress that develop at such interfaces. An effective biologic solution to thisproblem can be seen at the attachment
CAREER: FUNCTIONALLY GRADED BIOLOGIC MATERIALS- TISSUE ENGINEERING OF THE TENDON-TO-BONE INSERTION
During the Cenozoic, southwestern North America underwent a shift from Farallon subduction to the present Pacific - North American strike-slip plate boundary, the San Andreas fault system (SAF). As a result, much of the southwestern U.S. experi
Collaborative Research: Examining the Evolution of the Colorado Plateau and its relation to surrounding tectonic provinces using USArray data
Collaborative Research: Examining the Evolution of the Colorado Plateau and Its Relation to the Surrounding Tectonic Provinces Using USArray Data
The proposed studies examine a set of questions about how leaf microclimates - the temperature and relative humidity adjacent to a leafs' surface - influence insect-plant associations.  Frist, how different are leaf microclimates from nearby ma
CAREER:  Leaf microclimates and plant-insect interactions.
The research objective of this proposal is to develop a new regularization framework for effectively identifying molecular signatures under the following practical challenges: (a) small n large p data; (b) sparse signatures; (c) structured feat
Career: A New Regularization Framework for Identifying Composite Signatures
Protein production, trafficking and degradation are essential for proper cellular function. Perhaps no cells are more sensitive to imbalances in these tightly coordinated processes than neurons. An important cellular compartment, the endoplasmi
CAREER: An integrated analysis of torsinA, a conserved modulator of cellular homeostasis and neutonal function
A number of animal groups (e.g. mammals, birds, fish) undertake long-distance migrations between feeding and breeding grounds. The alternative evolutionary 'decisions' of migration versus permanent residency play important roles in maintaining
Career: Generic & Evolutionary mechanism of ecological divergence in migration tendency in salmonid fishes
Intellectual Merit. The PI proposes a fundamental research program to establish theoretical foundation for battery supported cyber-physical systems (CPS). Such systems play vital roles in real-time controlled applications across multiple discip
ARRA: CAREER: FEASIBILITY OF CONTROL TASKS-TOWARD CONTROL-COMPUTING-POWER CO-DESIGN
Multi-core processing platforms have an increasingly broad range of applications. From consumer multimedia to image processing to defense applications, new designs containing large numbers of embedded cores are emerging. Network-on-Chip (NoC) h
CAREER: Reliable On-Chip Wireless Communication Network for Multi-Core Systems
This project strives for novel and transformative approaches to design automation guided by physical views of computation. A broad theme is the application of expertise from an established field, digital circuit design, to new fields, such as n
CAREER: Computing with Things Small, Wet, and Random - Design Automation for Digital Computation with Nanoscale Technologies and Biological Processes
The cardiovascular system is the first operational organ system in developing vertebrates and proper control of its function, which transports oxygen and nutrients, is absolutely critical for the subsequent normal development of the animal. Any
CAREER: Maturation of Cardiovascular Physiology in Embryonic Reptiles
This is a CAREER award to support the research of Dr. Sheng Zhong, in the Department of bioengineering at University of Illinois at Urbana-Champaign. Dr. Zhong is a fourth-year, tenure-track Assistant Professor. Understanding cellular processes
CAREER: Computational Identification of Gene Regulatory Networks in Multicellular Eukaryotes
Ecosystems are incredibly complex because they include many species interacting with each other in a spatially and temporally varying environment. One tool ecologists use to cope with this complexity is mathematical modeling. Despite the fact t
CAREER: Modeling Complexity in Plankton Communities
The World Wide Web is a critical infrastructure that serves our society  by facilitating information exchange, business and  education. As it continues to evolve, the number of web-based  attacks that target innocent web users keeps increasing.
Framework for Preventing Web Based Attacks
Coastal evolution has become even more a concern under the scenarios of rising global sea levels, changing climate and accelerating human activities. World-wide, coastal erosion is becoming a still more serious problem than it already is. Being
CAREER: Multi-Scale Interactions of Waves, Currents and Morphology With Application to Rip Currents
Tectonic deformation, magmatism, and associated changes in erosion rates and paleodrainage systems directly affect sedimentary basin evolution in active tectonic settings.  Thus, a detailed and robust evaluation of convergent margin sedimentary
CAREER: Testing Models of Cretaceous Cordilleran Paleogeography: An Integrated Provenance Study of Four Basins
'The main objectives of this Faculty Early Career Development (CAREER) proposal are to discover atomic-scale details governing nanomaterials? response to irradiation, and to explore the possibilities of property-tuning to achieve extremely radi
CAREER: Radiation Response and Stability of Nanostructured Materials
While green engineering measures such as artificial turf, reflective roof coatings, and urban forests have proven advantageous in conserving resources in individual buildings, holistic modeling of urban meteorology and engineered systems at the
CAREER: Green Engineering of Urban Areas
'INTELLECTUAL MERIT Harmful levels of nitrogen (N) in estuaries can be diminished through tightly coupled processes in the microbial nitrogen cycle, including nitrification (chemoautotrophic oxidation of ammonia to nitrite and nitrate) and deni
CAREER: Spatial and Temporal Dynamics of Nitrogen-Cycling Microbial Communities Across Physicochemical Gradients in the San Francisco Bay Estuary
Understanding the hurricane boundary layer processes is of vital importance, not only to scientific study of hurricane genesis, development, and dissipation during landfall, but also to effective promotion of hurricane mitigation measures. Desp
CAREER: Investigation and Parameterizion of Hurricane Boundary Layer Processesfor Improving Hurricane Forecast and Mitigation
The goal of this CAREER proposal is to understand the limits and predictive power of string theory by: (1) investigating fundamental questions such as: Are there consistent models of quantum gravity that are not described by string theories? An
CAREER: Exploring Models of Quantum Gravity
Polysaccharides provide structural and mechanical properties for tissues and organs, and they have binding domains for proteins such as enzymes, cytokines, growth factors, and other extracellular matrix components. They are therefore excellent
Development of Complex Polysaccharide Nanostructures via Electrostatic Self-Assembly
This project will investigate the fate of organic matter in a cloud/fog system. First, scavenging efficiencies of particulate organic matter by fogs and clouds will be determined and parameterized based on simple measurable quantities like clou
CAREER: Cloud and Fog Processing of Organic Matter
Very small physical systems, where one or more dimension is reduced below 100 nanometers, often show framatically different behavior than larger objects.  Though research into this nanoscale regime is very active and has already revealed new ph
CAREER: Electrons, Phonon, and Magnons in Nanostructures and Novel Materials
The research will study the economic experiences and related social processes of people living with HIV/AIDS (PLWHA), how their financial conditions and economic survival strategies evolve over time, and how these processes shape and are shaped
CAREER: Resource Attainment and Social Context in Negotiating Illness Among Marginalized Populations
This collaborative project outlines a series of studies investigating the role of individual differences in executive functions (EFs) in expression of implicit racial bias. Executive functions refer to higher-order control processes that regula
COLLABORATIVE RESEARCH:  INDIVIDUAL DIFFERENCES IN EXECUTIVE FUNCTIONS AND EXPRESSIONS OF RACIAL BIASES
Professors Robert M. Metzger and Stephen A. Woski of the University of Alabama Tuscaloosa, and Professor Daniell L. Mattern of the University of Mississippi are supported by the Analytical and Surface Chemistry Program in the Division of Chemis
Title: SUBREGIONAL ANALYSIS OF THE HUMAN MEDIAL TEMPORAL LOBE IN EPISODIC MEMORY.  This project will use high-resolution neuroimaging to investigate how different parts of the human medial temporal lobe contribute to different memory functions.
SUBREGIONAL ANALYSIS OF THE HUMAN MEDIAL TEMPORAL LOBE IN EPISODIC MEMORY
When speakers encode their thoughts into linguistic utterances, they often can choose between several different ways of conveying the same message. For example, English speakers may use an active or a passive. They are more likely to choose a p
COLLABORATIVE RESEARCH: STUDYING LANGUAGE PRODUCTION IN THE FIELD: ACCESSIBILITY EFFECT ON VARIATION
WHITEHEAD INSTITUTE FOR BIO-MEDICAL RESEARCH
In this project the PI proposes to measure, analyze, and model chromosome conformation based on the imaging of an extensive collection of fluorescently-labeled strains in prokaryotic cells. The PI will also introduce the co-variance matrix for
Biophysics of the bacterial nucleoid: Structure, replication, and segregation of the E. coli chromosome
' The Analytical and Surface Chemistry Program in the Division of Chemistry supports work by Professors Carolyn Cassady and David Dixon at the University of Alabama - Tuscaloosa aimed at enhanced understanding of the gas-phase chemistry of depr
Mass Spectrometry and Computational Studies of Deprotonated Peptides and Amino Acid Amides
This proposal centers on the development and application of novel set of multi-dimensional nuclear magnetic resonance experiments for establishing through-bond connectivity and chemical shift assignments in disordered solids using scalar coupli
Structure and Dynamics with Solid-State NMR
An observational study is an empiric investigation of the effects of a treatment, policy, intervention or exposure which was not randomly assigned to subjects, as it would be in a randomized experiment. Observational studies are common in most
DESIGN AND INTERPRETATION OF OBSERVATIONAL STUDIES
Annotating the Cis-Regulatory Binding Sites in Sequenced Prokaryotic Genomes  University of North Carolina at Charlotte has been awarded a grant to develop software and a database resource for characterizing cis-regulatory binding sites in sequ
Annotating the Cis-Regulatory Binding Sites in Sequenced Prokaryotic Genomes
'This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).'The cycles of organic carbon and oxygen are linked by the stoichiometry of photosynthesis and respiration, the mass balance of oxygen in the uppe
A common perception is that sharks are small-brained animals with a limited behavioral repertoire. Recent research has been dispelling these myths and has found that sharks possess brains that are of comparable size to birds and mammals. One br
The Evolutionary Origins of the Vertebrate Brain: Neural Organization and Complexity in Chondrichthyans
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).                       Although natural radioisotopes, such as Th(IV), Pa(IV, V), Po(IV, II, -II), and Be(II), are important proxies that have long
Collaborative Research:  Examining the Binding of Radionuclides with Marine Biopolymers. A Comparat
The award will provide funding for planning and implementing workshops and other supporting activities associated with the Political Networks Conferences in 2009, 2010, and 2011, including funding for approximately 40 graduate and assistant pro
Political Networks: Conference and Infrastructure Development
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). The Smithsonian Environmental Research Center (SERC) on the Chesapeake Bay will offer an REU program in environmental biology to ten undergraduate
REU Site:  Research Experiences for Undergraduates at the Smithsonian Environmental Research Center
There is a growing demand to assess various measures of human well-being (including socio-economic and health characteristics) at national and sub-national levels. However, data availability at the sub-national level is often limited owing to c
Collaborative Research: Computation-driven Small Area Interference with Applications
This 3-year REU site program at Rutgers University will engage 10 undergraduate students each year in cutting-edge, cross-disciplinary research in the field of Cellular Bioengineering. Cellular Bioengineering encompasses a number of cutting edg
REU Site: Cellular Bioengineering--From Biomaterials to Stem Cells
Nanotechnology is now accepted as one of the greatest areas for technological innovation and economical advancement. Its worldwide societal impact has been quantified in 2 million workers who will produce nanotechnology-based products worth $1
Understanding the Interactions between Carbon Nanotubes and Cellular Membranes
To construct an 8 acre expansion to the barge dock at Port MacKenzie which will enhance the Port's ability to receive/send cargo.
Bridge Deck Replacement Program I-78 Ramp A over I-78, Design
Name of Project: ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act. The funds reflect a 4.90% COLA increase for all Head Start/Early Head Start staff
SOUTHERN IOWA ECONOMIC DEVELOPMENT ASSOCIATION
Southern Iowa Economic Development Association (SIEDA) provides center based Head Start programming, including educational, health, nutrition, social/emotional and parent education services to 284 children and their families in a 7 county area
Award Title:ARRA-COLA & QUALITY IMPROVEMENT FOR Head Start and Early Head Start  ARRA COLA  All Head Start (HS) and Early Head Start (EHS) staff will receive an additional COLA salary and fringe benefit increase of 1.84%. No salaries exceed the
ECONOMIC SECURITY CORP OF SOUTHWEST AREA
Head Start Quality Improvement and COLA (ARRA) These funds provided a cost of living increase of 1.8% for head start staff.  In addition, at least 50% of the designated Quality Improvement funds were used to improve compensation and benefits fo
GEARY COUNTY UNIFIED SCHOOL DISTRICT 475
FY2009 ARRA COLA/QI This award provides for ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start program.  Head Start promotes the sc
Head Start Expansion (ARRA); Total Number of Children Served-36; Program Options-Head Start Part-Day Center-Based; Counties Served-Lancaster and Saunders Counties in Nebraska; Purpose-Head Start promotes the school readiness of low-income child
The ARRA Head Start Expansion funds provided for an additional classroom with 20 children enrolled.  This Head Start Expansion Grant is for two years.  This classroom promotes school readiness and healthy family functioning.   This classroom op
I-80 from 8.7 ME of Nightingale Intg. To Churhill/Pershing County Line. CH 12.83 TO CH 27.71.
Highway Infrastructure Investment - Bridge rehabilitation, no added capacity (no added traffic lanes) - From funding for use in any Area
Highway Infrastructure Investment - Interstate reconstruction, with added capacity (added travel lanes) - From funding for use in any Area (flexible)
Interstate 80, Missouri River to 13th St.
Highway Infrastructure Investment Grant: Areas with Population equal to or less than 200K and Available for Use in Any Area (Flexible)
Safety and Resurfacing Downes Road to PA Line/Ramps at MD 45, Mt Carmel Road and Middletown Road
on this science mission become practicing scientists and engineers. The new, largely unproven technology involved in CubeSat missions inherently makes the project associated with significant risks. On the other hand, however, the project has t
Collaborative Research: CubeSat: Focused Investigations of Relativistic Electron Burst Intensity, Range, and Dynamics (FIREBIRD)
How does the Himalaya rise up to today's height? How is the Tibetan Plateau (TP) formed? How is the crust of plateau deforming to produce great earthquakes, such as the one we witnessed on May 12, 2008 in Wenchuan, China, which killed over 70,0
Collaborative Research: Joint Inversion of Crust and Upper Mantle Structure in Central and Eastern Tibetan Plateau and its Margins
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  Continent collisions can form large plateaus, like Tibet, producing thick crust and high topography that affects climate change. How plateaus gro
How Does the Lower Crust Thicken and Grow During Continent Collisions? A Case Study of the Pamir
Much of the inventory of East Antarctic bedrock geochronology, as well as a record of its erosional history, is preserved in Cenozoic sediments around its margin. This project is to use these sediments to understand their sub-ice provenance and
Collaborative Research: Erosion History and Sediment Provenance of East Antarctica from Multi-method Detrital Geo- and Thermochronology
Collaborative Research: Erosion History and Sediment Provenance of East Antarctica from Multi-Method Detrital Geo- and Thermochronology
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). Plasma waves and radiation play key roles in space physics, in some cases playing an important role controlling particle transport, loss rates, or
Collaborative Research: Multi-instrument Studies of Auroral Plasma Radiation
OFFICE OF SPONSORED PROJECTS 11 ROPE FERRY RD #6210
AbstractThrough modeling and data assimilation studies, University of Washington researchers seek to reconcile information on Antarctic sea ice and its interaction with the upper ocean and the atmosphere, throughout the modern era of satellite
ARRA Variability and Trends in Antarctic Sea Ice
This award supports a project to conduct a modeling study of the ice stream - sub-glacial water system. A suite of numerical models of various dimensionality and complexity will be constructed in a sequential, hierarchical fashion to formulate
Model Investigation of Ice Stream/Subglacial Lake Systems
his effort seeks to develop a better understanding of how the nonlinearly coupled thermosphere and ionosphere are driven asymmetrically in polar storm events, and how coupling between these domains affects overall system-level response. Goals o
The RAGES project (Robotic Access to Grounding zones for Exploration and Science) is one of three research components of the WISSARD (Whillans Ice Stream Subglacial Access Research Drilling) integrative initiative that is being funded by the An
Collaborative Research: Integrative Study of Marine Ice Sheet Stability and Subglacial Life Habitats in West Antarctica-Robotic Access to Grounding -zones for Exploration and Science Award
The Los Alamos Summer School is a ten week program for undergraduate physics students held in Los Alamos, New Mexico, with the support of the University of New Mexico and Los Alamos National Laboratory.  The school's principal aims are to expos
REU: The Los Alamos Summer School in Physics
With this award from the Chemistry Research Instrumentation and Facilities Multiuser Program (CRIF:MU), the Chemistry Department at Jackson State University (JSU) will acquire a multi-user GC-triple quadrupole mass spectrometer. The spectromete
CRIF MU: Acquisition of a Multi-User GC-MS Instrument
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  With this award from the Chemistry Research Instrumentation and Facilities Multiuser Program (CRIF:MU), Professor Carol A. Fierke from the Univer
CRIF: MU Purchase of a Single Crystal X-Ray Diffractometer
The overall goal of this project is to increase understanding of the conjugate nature of the polar ionospheres, which in part helps understanding the multi-scale global solar wind, magnetosphere, and ionosphere system. The project utilizes nume
African cichlid fishes provide a unique system for understanding how genomic information (DNA) is converted into whole organism variation (e.g., differences in size, shape, color). There are more than 2000 species of cichlid fishes, making them
CAREER: Proximate and Ultimate Causes of Sensory System Evolution
This project examines two groups of highly unusual members of the blueberry family, including some species without leaves. Goals  include how to tell the species apart, and determining how the species in each group are related to each other and
(ARRA) Systematics of Monotropoideae and Pyroloideae (Ericaceae)
Freshwater ecosystems provide vital ecological services important to human well being such as drinking water, food resources, and recreation. These systems are vulnerable to disruption of these services if human activities and their impacts exc
Water and energy are essential ingredients of life and key commodities for humans and other living organisms that make up food webs. Curiously, although the role of energy in determining the inner workings of food webs has been thoroughly explo
Quantifying the effects of groundwater and hydrology on trophic structure in desert riparian ecosystems
Neurons transmit electrical information through long axons to distant parts of the brain and body. The cell bodies of neurons must also receive information from their targets, however very little is known about how this 'retrograde' information
The Role of Axonal Transport Machinery in Signal Transduction
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  This project examines the effects of the immediate social and physical environment on pain sensitivity (nociception) in laboratory mice, primaril
RUI: Environmental Modulation of Nociception
in genomes that specify when, where, and under which conditions each gene will be expressed, and epigenetic influences that specify biological context to which a genome responds. This project investigates a complex odorant receptor gene regula
Cross-Disciplinary Science and Investigation of Olfactory Receptor Gene Regulation
Objects, people and events around us tend to occur in typical contexts. Ovens appear in kitchens, traffic lights tend to appear in streets, and a beach-umbrella appears next to a beach-chair and a towel. These regularities in our environment---
ARRA: Contextual Contribution in Brain and Cognition
By the time children enter preschool, most are phenomenal word learners, adding new words to their vocabulary every single day. It is clear, however, that not all words are learned with equal ease. What factors determine whether, and how rapidl
Crassulacean acid metabolism (CAM), a photosynthetic pathway found in approximately 7% of all vascular  plant species that improves water use efficiency up to 10-fold relative to C3 species, provides an exquisite example of circadian and enviro
Regulatory and Signaling Mechanisms of Crassulacean Acid Metabolism:  A Photosynthetic Adaptation to Environmental Stress
Anyone who has had a phone conversation about how to how to change the oil in a car or how to make lasagna knows the importance of explanatory gestures for communication. Multimodal discourse involves the use of both visual (gestures) and audit
Understanding Multi-Modal Discourse: Cognitive Resources and Speech-Gesture Integration
The insect and arthropod collections of the A.J. Cook Arthropod Research Collection (ARC) at Michigan State University (MSU) contains ~1.1 million pinned and labeled specimens and also, specimens in 114,000 vials and on 47,000 slides. Approxima
Physical renovation and electronic expansion of the A.J. Cook Arthropod Research Collection at Michigan State University
Absolute ages for the deposition of sedimentary rocks can be determined by radiometric dating of organic material in carbon-rich shales, using the decay of rhenium (Re) to osmium (Os). In particular, fossils of organic-walled graptolites are co
Direct Re-Os Dating of Ordovician Graptolite Biozones:  Refining Global Correlations and Earth Time
Archean and Proterozoic oceans have no known analogues in modern aquatic environments, and their biogeochemistry and microbiology remain enigmatic. Lake Matano's physical structure, abundance of Fe and dearth of sulfate mirror the stratified fe
Collaborative Research: Lake Matano, Indonesia: A modern observatory of ancient ocean biogeochemistry
This project will investigate the physiology of Sonoran Desert winter annual plants in order to provide insights into their population and community dynamics and the mechanisms that allow species to coexist at high diversity. Annual plants are
Individual function and community processes in desert annuals
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).'   Objective: The objective of this research is to experimentally understand the requirements for manipulating light in waveguides using electron
CAREER: Spin-dependent Optoelectronic Devices for Integrated Photonics
The traditional separation between the 'structure-only' Database world and the 'text-only' Information Retrieval world is fading. Databases now routinely include text components while documents are being augmented with structural information. T
CAREER: Relaxed Content and Structure Queries Over Hetergeneous Data
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).    The objective of this research is to overcome the limited bandwidth density and energy scaling of electrical interconnects, which have caused a
CAREER: Circuit and System Techniques for High-Throughput, Energy-efficient Silicon Photonic Interconnects in Advanced VLSI Systems
The Organic and Macromolecular Chemistry Program in the Chemistry Division at the National Science Foundation supports Professor Suri S. Iyer at the University of Cincinnati who will synthesize ligands that exhibit antibody-like selectivity, ar
CAREER: Tailored Glycoconjugates for the Precise Detection of Toxins and Pathogens
CAREER: Biomolecular Interactions that Regulate the Cellular Reaponse to DNA Damage
TPROPOSAL 0845120This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).The objective of this research is to investigate a new system-on-brain paradigm, one of the next great challenges of the integrate
CAREER: A Scalable, Ultra-Low Power Active Fabric for ECoG
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  Sources and sinks of carbon dioxide (CO2) and methane (CH4) in forests, wetlands, and lakes significantly alter the impact of fossil fuel emissio
ARRA CAREER: Contrasting environmental controls on regional CO2 and CH4 biogeochemistry-Research and education for placing global change in a regional, local context
Non-Technical abstract:    This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). This CAREER award funds a project to understand the mechanism of superconductivity in cuprates by studying dynamics of
CAREER: Non-equilibrium Dynamics in Cuprate Superconductors Studied by Coherent Ultrafast Spectroscopy and Ultrafast Electron Diffraction
The CAREER project integrates next-generation molecular genetics with an aggressive education strategy to prepare students and professionals in genomics and to communicate the importance of science to the public. The research questions asked ar
CAREER: Research, Education, and Capacity Building - Genomic Structure of Native Peruvian Populations
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).The scientific data management landscape is changing. Improvements in instrumentation and simulation software are giving scientists access to data
CAREER:Interactive and Collaborative Data Management in the Cloud
INTELLECTUAL MERIT  Indole-3-butyric acid (IBA) is a natural ly-occurring compound in the auxin family of plant hormones. Auxins play critical roles in growth, development, and response to environmental cues, especially in root morphology. Beca
CAREER: Molecular Mechanism of Indole-3-Butryic Acid Action in Arabidopsis
Nonlinear internal waves (NLIWs), ubiquitous features of the coastal ocean and lakes, are on the receiving end of an energy cascade initiated at large scales by the winds and tides in stratified natural water bodies. These waves transport this
CAREER: SHOALING OF NON-LINEAR INTERNAL WAVES OVER GENTLE SLOPES: WAVE-SCALE INTERACTIONS AND DISSIPATIVE PROCESSES
INTELLECTUAL MERIT: The long-term goal of this project is to develop new, broad-spectrum antimicrobial agents. The central hypothesis is that the preassembly of membrane-active polymer chains will enhance their cooperative ability to perforate
CAREER: Functional Scaffolds for Polymeric Antimicrobial Agents
In the evolution of biological organisms, the ability to see has been a popular feature for millions of years. However, the majority of machines built today remain essentially blind to the photons that continually bombard them. Effective real-t
CAREER: Energy-Efficient Parallel Architectures for Computer Vision
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).The research objectives of this project are to elucidate the mechanisms and importance of nocturnal nitrogen oxide chemistry in the polluted marine
CAREER:  In Situ Constraints on Nocturnal Nitrogen Oxide Chemistry in Forested and Marine Environments
CAREER:  Cooperative Human-Computer Model Updating Cognitive Systems (MUCogS) The research objective of this early career development (CAREER) project is to develop a framework for cooperative human-computer Model Updating Cognitive Systems (MU
CAREER:  Cooperative Human-Computer Model Updating Cognitive Systems (MUCogS)
Advances in high-performance computing have enabled the scientific community to progress toward the Direct Numerical Simulation of whole blood, at least in microcirculation. Despite the complexity of the problem, many research groups have succe
CAREER: Convective and Diffusive Transport of Drug Delivery Vehicles in Blood Flow in Microcirculation
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).    The objective of this research is to push the limits of electronics to THz frequencies and to increase society's awareness to the new possibili
CAREER: Terahertz Electronics based on Nitride Nanowire Transistors
Early Career Development (CAREER) project is to develop a new flexure system design methodology inspired by elastic averaging, which is seen in nature. Flexures are jointless elastic structures that derive motion from material compliance, which
CAREER: Elastic Averaging - Nature's Design Paradigm for High Performance Flexure Systems
Intellectual Merit:   This project will provide tools and methodologies that will enable advancements in the formulation, identification and analysis of mechanistic mathematical models of protein-protein and protein-DNA interaction networks. Al
CAREER: A HYBRID EXPERIMENTAL AND COMPUTATIONAL PROGRAM TO ELUCIDATE THE MOLECULAR DIFFERENTIATION PROGRAM OF A MODEL STEM CELL
Why do some children in susceptible families become autistic when others do not? How can understanding what goes wrong in autistic brain development help us to understand what goes right in normal brain development? And how might this knowledge
CAREER: INTEGRATIVE BEHAVIORAL AND NEUROPHYSIOLOGICAL STUDIES OF NORMAL AND AUTISTIC COGNITION USING VIDEO GAME ENVIRONMENTS
for incorporation into teaching activities.
CAREER:  Oligocene planktonic foraminiferal Konservat-Lagerstaette:  Implications for taxonomy, paleobiology, and tropical marine temperatures
This CAREER proposal describes a detailed research plan that will allow precision measurements with the CMS experiment to be carried out in the challenging environment of very high luminosity proton-proton collisions. The proposal integrates th
CAREER: New Trigger Instrumentation and Precision Measurements with the CMS Detector at the Super-LHC
This Faculty Early Career Development (CAREER) Award supports a project to investigate novel quantum physics, inspired by high energy nuclear and particle physics, in graphene (a nanomaterial). Graphene is the building block of many carbon mate
Career: Table Top High Energy Physics in Graphene
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). This CAREER award, funded by the Experimental Physical Chemistry Program of the Chemistry Division, supports an experimental research program by P
CAREER: Correlation of Electronic and Nuclear Coupling in Biological Photoreceptors using Femtosecond Multidimensional Spectroscopies
'A three year old infant can recognize visual objects better than any machine. Despite decades of work on the problem of complex object recognition, the principles used by the brain to solve this problem are still unknown. One major experiment
CAREER: Dissecting the Neural Mechanisms for Face Detection
The Southwest Environmental Information Network (SEINet) was initiated at the Global Institute of Sustainability (GIOS) at Arizona State University.  It was created to serve as a gateway to distribute data resources of interest for the environ
The primary goal of this proposal is to computerize taxonomic, geographic, and stratigraphic information for catalogued invertebrate fossils at the University of Michigan Museum of Paleontology (UMMP-IC). The UMMP-IC has long ranked among the m
University of Michigan Museum of Paleontology invertebrate fossils: Databasing and web-accessibility
Through its 56-year history, the Ichthyology Collection (at the Virginia Institute of Marine Science (VIMS) has grown from an un-cataloged teaching collection to become one of the largest repositories for freshwater, Chesapeake Bay, coastal, an
Renovation of the Ichthyology Collection and Associated Facilities at the Virginia Institute of Marine Science
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  In this project, alkylative dearomatization processes will be developed for synthesis of the polyprenylated phloroglucinol natural products. In p
An Alkylative Dearomatization-Annulation Approach to the Polyprenylated Phloroglucinol Natural Products
This project will continue studies on the development of new methods for the direct formation of C-N bonds via activation of C-H and C-C bonds. Four new aspects of catalytic nitrogenation reactions are targeted for study during the next funding
Amines are volatile organic compounds (VOCs) emitted to the atmosphere from a number of sources including intense emissions from animal feeding operations (AFOs). In the atmosphere, amines act as precursors for aerosols, but the fates of amines
International crises occur when two states confront each other with mutually incompatible demands. In general, states will not make concessions unless they are convinced that the alternative of fighting will be even more unpleasant. Crisis nego
Conflict Bargaining with Endogenous Distribution of Power
'Firms, governments, and scientists are constantly striving to figure out what goods and services people want most and quantify their worth. The main technique used to do this in economics is to statistically analyze data on what people have b
Using Neurometric Data To Measure Economic Values in Private and Social Exchange Situations
Conduct modernization activities at public housing developments. Remoderization of 4 two story units  and painting and viynal siding of 46 units
This project will continue work on developing powerful new reactions and strategies for chemical synthesis. The proposed research aims to develop highly useful synthetic methods centered on the use of N-allylhydrazones as readily prepared compo
CAREER: Unlocking the Synthetic Potential of N-Allylhydrazones
An Integrated Multiscale Platform for Fundamental Studies of Peptide Self Assembly Peptides are exceptionally versatile platforms for tunable molecular self assembly, forming an impressive variety of nanoscale morphologies in response to cues s
CAREER: An Integrated Multiscale Platform for Fundamental Studies of Peptide Self-Assembly
Host plant resistance is the most effective, economical, and environmentally friendly way to control plant diseases. Although significant progress about the interaction of plant NB-LRR-type resistance gene and the corresponding bacterial effect
CAREER: Understanding the exceptional broad taxonomic functionality of a maize disease resistance gene and the cognate bacterial effector
Internet-connected computer systems face ongoing software attacks. Existing defensive solutions, such as intrusion detection systems, rely on the ability to identify malicious software (malware) in order to prevent its installation. This approa
ARRA: CAREER: LOCAL REMEDIATION OF GLOBAL INTERNET EPIDEMICS
CAREER:   Computational Analysis and Prediction of Genome-Wide Protein Targeting Signals and Localization A typical cell has a size of only 10 m while it contains about a billion proteins. How these many proteins are transported from their synt
CAREER:   Computational Analysis and Prediction of Genome-Wide Protein Targeting Signals and Localization
Policy-based computing is a critical component of many large-scale configurable systems because it enables dynamic adaptability of system behavior by changing policy configurations without reprogramming the systems. Policy evaluation, the proce
CAREER: Towards High Performance Policy Evaluation
Intellectual Merit. High throughput sequencing that allows human genetics to access rare variation 'Next Generation' sequencing is transforming human genetics: several disruptive technologies are coming of age and now enable resequencing throug
CAREER: Computational Infrastructure for Full-Sequence Association Studies with Pooled Individuals
Processors with tens or possibly hundreds of cores will be a reality within the next few years. To ensure that multi-core performance will scale with the increasing number of cores, innovative processor architectures are increasingly being depl
CAREER:  New Foundations for Many-core Architecture, Analysis, Modeling and Management
The basic hardware technology that is used to build microprocessors and the applications we run on them are are radically changing. Hardware building blocks are becoming increasingly brittle and error-prone, leading to a fundamentally unpredict
ARRA CAREER: A Vertically Integrated Approach to Microprocessor Design for Unpredictable Silicon
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).When we open our eyes we instantly -- without any apparent effort -- have a detailed three-dimensional (3D) representation of our environment. Howe
CAREER:Neural mechanisms of object size perception
Engineered nanomaterials have unique chemical and physical properties that make them desirable for widespread applications including environmental remediation, energy conversion, catalyst support and biomedical use. Despite their benefits, ques
CAREER: Research and Education of Adsorption and Desorption of Air Pollutants on Engineered Nanomaterials
The project will focus on a rigorous analysis of wave propagation in disordered media, along with related analysis of random operators and matrices. The goal is to establish diffusive propagation of waves in a weakly disordered medium over arbi
The objective of this award is to perform the fundamental research necessary to advance the electric power grid integration of diverse variable renewable energy resources. The approach is separated into three tasks: first, building the tools to
CAREER: Advancing Grid Integration of Diverse Renewable Energy Sources
The research objective of this proposal is to use predictive simulations using innovative numerical methods and minimal empiricism to understand the physical processes that govern mixed flow/powder-snow avalanches (MA). MA consist of a dense co
CAREER:  Predictive Simulations of Dilute-Dense Multiphase Flows and Application to Mixed Avalanches
Spatial analysis is essential to the acquisition, transformation, and use of spatial data, information, and knowledge for scientific discovery and decision-making in many fields (e.g., ecology, environmental science and engineering, geography,
CAREER: Formalizing and Resolving Computational Intensity of Spatial Analysis to Establish a Cyber-GIS Framework
This proposal is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  Prof. Stephen Cronin at the University of Southern California is supported by the Division of Chemical, Bioengineering, Environmental, and Tra
CAREER: Enhanced Catalytic Phenomena via Surface Plasmon Resonant Excitation
****NON TECHNICAL ABSTRACT**** This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). Many natural and synthetic systems involve ordered arrangements of units on two-dimensional surfaces. Examples incl
ARRA: CAREER: ORDERED MATERIALS IN CURVED SPACES
Dr. Rose Finn (Siena College) will quantify the relative importance of the physical mechanisms that cause galaxies to evolve from blue, actively star-forming galaxies to red, passive galaxies by studying the gas and stellar properties of galaxi
CAREER: Gas Stripping in Low_Redshift Groups and Cluster
The project addresses basic electronic/photonic materials research issues in a topical area of materials science with high technological relevance. The success of the research activities will enable development of devices that will impact impor
Career: Anitmony-Based Nanowires and Nanowires Heterostructures: Synthesis and Characterization
Nearly one hundred years after the discovery of cosmic rays, neutrino telescopes are becoming an integral part of a multi-messenger approach to discovering their still elusive origins. Neutrinos are unique astronomical messengers which may prov
CAREER: Towards a GZK Neutrino Detector at the South Pole
The United States is the only advanced industrial country without publicly financed national health care or compulsory national health insurance, it has a public welfare state that is one of the smallest in the western world, and consequently t
CAREER: Tax Progressivity and American Political Economy
The present project is focused on reactions of electrophilic metal-carbon bonds with substrates featuring strong C-N bonds in order to understand the mechanism of intimate reaction steps. The breaking of C-N bonds in heterocycles is a significa
CAREER:  REACTIONS OF ELECTROPHILIC METAL CENTERS WITH AROMATIC HETEROCYCLES
Understanding how the brain's neuronal networks perform computations remains a difficult challenge. The interaction of large populations of neurons leads to a complex repertoire of high-dimensional activity patterns that is difficult to analyze
CAREER: Toward a second order description of neuronal networks
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  TECHNICAL SUMMARY:  The primary objectives of this CAREER project are to understand the interplay of nanostructure design and material properties
CAREER: III-nitrides Nanowire Superlattice for Nanoscale Laser Diodes
Urgent Needs for the NCSU Research Collection  	The equipment, infrastructure, databasing, training, and research proposed herein facilitate a transcendence from specialized resource for researchers in Entomology and a handful of systematists w
NC State University Insect Museum: Safeguarding and Developing a Community Resource
Young etiolated seedlings have little or no protection against abiotic stressors. It is therefore germane that we understand the signal transduction systems activated by abiotic stresses and how these signal transduction systems operate to prod
G Protein Regulation of Phenylalanine Synthesis
The Genetics of Innate Immunity and Disease Resistance in Reef-Building corals
This Research award in the Inorganic, Bioinorganic and Organometallic Chemistry program supports work by Professor Russell P. Hughes at Dartmouth College to carry out fundamental studies on the chemistry of perfluoroalkyl and perfluoroalkyliden
Reactions of Transition Metal Perfluoroalkyl and Perfluoroalkylidene Complexes
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). The Inorganic, Bioinorganic and Organometallic Chemistry Program supports the efforts of Professor James Gardinier of Marquette University for the
Multinucleating Pendtadentate Ligand Scaffolds for Cooperative Bimetallic Oxidation Reactions
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  A recent global census of surface loopers (drifter trajectories with a definite sense of rotation) has revealed some unexpected features of the d
Collaborative: What do global surface drifters tell us about submesoscale processes
The purpose of this project is to observe and understand the interannual flow near the eastern tropical Pacific boundary. Satellite altimeter and coastal tide gauge data will be used to document and understand the tropical eastern Pacific inter
Equatorial Wave Reflection and Equatorial Warm Water
Florida State University, University of Texas at Austin and the University of Kansas are collaborating to create a distributed information system that integrates image-based morphological data to improve species and specimen identification. In
Collaborative Research: Data Integration Services for Biodiversity Informatics
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  The Hope College REU program in Computer Science is designed to provide promising undergraduates with an intensive and meaningful research experi
REU SITE: An Undergraduate Research Program in Biomedical Applications in Computer Science
This REU site is focused on cognitive communications at Virginia Polytechnic Institute, and hosts 10 undergraduate students for 10 weeks for 3 years. The site recruits, trains, and retains undergraduate students to research by supporting them i
CAPABLE (Coastal Autonomous Profiling and Boundary Layer System) development began three years ago under OTIC funding with a partnership between Oregon State University's College of Oceanic and Atmospheric Sciences (COAS) and Western Environmen
Development and Testing of a Coastal Autonomous Profiling and Boundary Layer System (CAPABLE)
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).This project will develop probability models and inferential methods for the analysis of data collected using Respondent Driven Sampling (RDS). RDS
Statistical Inference for Chain Referral Data from Respondent Driven Sampling
Securing a high and stable supply of blood and blood components is indispensable not only to face emergencies such as accidents and surgeries, but also to meet the increasing demand for blood for chronic diseases and certain types of cancer. Th
Field Experiments on the Provision of Incentives for Blood Donation.
This three year Research Experiences for Undergraduates (REU) Site program at the University of Kentucky will engage students in research focused in the fields of Electrical and Computer Engineering. The program objectives are as follows: 1) pr
REU Site in Electrical & Computer Engineering at The University of Kentucky
This CRI proposal is designed to enhance the community's computing research infrastructure in support of smart environments. The goal of this program is to equip physical smart environment testbeds, and disseminate the data and software tools t
II-EN: Smart Environment Infrastructure for Resident and Environment Modeling
Experimental and theoretical studies of protein aggregation lag considerably behind protein folding studies, because of their much greater complexity. Several researchers have developed molecular dynamics simulations of protein misfolding and a
ARRA Folding and Aggregation of Polyglutamine Peptides and Proteins
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  The newly discovered process of anaerobic ammonium oxidation (anammox) is an important process in marine environments. The contribution of anammo
Collaborative Research: Environmental Controls on Anammox and Denitrification Rates in Estuarine and Marine Sediments
Seminal insights towards establishing contributions of sensory biology to community ecology.
THE SENSORY BASIS FOR ECOLOGICAL PARADIGMS ON WAVE-SWEPT SHORES
Skin is our largest organ, serving critical roles in fluid homeostasis, thermoregulation, immune surveillance, and self-healing. Disease and/or the loss of major portions of a human's skin can be disabling and potentially life threatening, and
3-D Optical Tracking of Bone Marrow Derived Skin Stem Cells
This award provides continuing support for a program of research for the High Energy Physics group at Syracuse University. The Syracuse HEP group is the only U.S. group on LHCb - an experiment at the LHC designed as the first to study b and c d
This research project will evaluate the effect of the presence of bubbles on the turbulence structure, velocity distribution and ultimately the water entrainment caused by surface jets, as well as the resulting gas phase distribution. There is
Experiments and Modeling of Bubbly Surface Jets
0853988, 0853568, 0853409 Boehm, Nelson, McNeill  Current assessment of microbial pollution in recreational waters involves measurement of fecal indicator bacteria (FIB) as proxies for human pathogens. FIB concentrations display diurnal variabi
Collaborative Research: The role of sunlight in controlling fecal indicator bacteria and human virus concentrations in recreational waters
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).    The project will develop a new framework for mathematical modeling of rechargeable batteries, taking into account statistical thermodynamics, c
FRG: Collaborative Research: Mathematical Modeling of Rechargeable Batteries
'This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).'   The goal of this project is the documentation of spontaneous connected speech, with a focus on conversation in natural settings, in two langua
Athabascan Spoken Language Corpora: Ahtna (aht) and Navajo (nav)
'This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).' What Tlingit conversations do birth speakers of Tlingit use to carry on their daily lives? What record of daily functional language will learner
Documenting Tlingit (TLI) conversations in Video and Time-Aligned Text
University of Alaska Southeast Juneau Campus
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). 0853817/0853396Hermanson/TryggvasonThis preliminary experimental and computational research program will study the physical mechanisms of disrupti
Collaborative Research: Fuel Droplet Disruption under Locally Supersonic Conditions
Public Safety, Disaster Services, General/Other
The goal of the PI is to make a significant contribution in cardiovascular tissue engineering though research, education, and the transformation of stem cell engineering. In this context, stem cell engineering includes the design of cell and dr
Dual growth factor delivery to achieve therapeutic neovascularization
Monitoring of effluents from point contamination sources and protection of drinking water supplies is a main environmental concern of any engineering solution aimed at minimizing contamination to surface waters should include a system capable o
Physiologically-Coupled Biosensing Approaches for real-time Monitoring of Environmental Contaminants
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).Accurate modeling of power, leakage, and timing while accounting for process variations, is crucial for the manufacturable design of nanoscale Comp
Infrastructure Acquisition for Statistical Power, Leakage, and Timing Modeling Towards Realization of Robust Complex Nanoelectronic Circuits
This is an integrated research and education project to study  adsorptive separations of chiral enantiomer pairs, or racemic mixtures. These separations are a critical problem of the pharmaceutical and fine chemicals.       A new approach is us
Experimental Probing and Molecular Modeling of Key Sorbent-Solute-Solvent Interactions in Chiral Separations
The NSF award by the Chemical and Biological Separations program supports work by Professors S. Ted Oyama and Luke E. Achenie at Virginia Polytechnic Institute and State University to develop advanced membranes for CO2/CH4 separation. The studi
Experimental and Theoretical Studies of Advanced Inorganic Membranes for CO2 Separation
ASSOCIATION OF UNIVERSITIES FOR RESEARCH IN ASTRONOMY INC
The National Solar Observatory (NSO) International Research Experience for Students (IRES) Program provides qualified and motivated US graduate students with the opportunity to perform scientific research at the Indian Institute of Astrophysics
US-India IRES Summer Program in Astrophysics
'The project investigates temperature controlled activation of micro nano structured nanocomposite hydrogel materials to produce temperature controlled self cleaning surfaces. Cyclical changes in temperature will activate these nanocomposite hy
Micropatterned Thermoresponsive Nanocomposite Hydrogel Surfaces with Self-Cleaning Behavior
Research and Development in Biotechnology
The main objective of the proposed research is to find a geometrically meaningful compactification of the moduli space of polarized K3 surfaces, obtained as an instance of Mumford's theory of toroidal compactifications.The theory requires a fan
Mathematical models taking both deterministic and stochastic factors into account are becoming increasingly important in science and technology. These models, as a rule, are rather complicated. Oftentimes, they include many parameters character
FRG:  COLLABORATIVE RESEARCH:  STOCHASTICS AND DYNAMICS:  ASYMPTOTIC PROBLEMS
Generalized geometries form a class of almost complex manifolds with reduced structure groups, which have become of central importance to the study of realistic string theory models. These are natural generalizations of Calabi-Yau manifolds and
FRG: Collaborative research: Generalized Geometries in String Theory
The objective of this project is to inspire students at Tuskegee University and Auburn University in mathematics, aerospace science engineering, and networking by inviting them to contribute to a grand project: fly safely and efficiently, in a
Collaborative Research: CRI-RUI: II-NEW: ATTRACT: Aerial and Terrestrial Testbed for Research in Aerospace, Computing, and maThematics
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).    Numerous interesting applications have been enabled by embedded sensing technologies and significant research progress on wireless sensor netwo
II-EN: A Heterogeneous Networking Test Bed to Support Middleware Services for Pervasive Sensing
One of the grand challenges in robotics is to achieve dexterity, especially dexterity in manipulation. The equipment funded by this project ? a robot torso, two arms, and a custom designed robot hand, supports investigation of manipulation task
II-EN:  Robotic Equipment for the Investigation of Dexterous Two-Handed Manipulation
This project involves precise measurements of the properties of the lead flouride molecule to hunt for a property of the electron known as its electric dipole moment or EDM.   This hunt continues a 58-year-old search initiated by Nobel prize wi
Measurement of the Electron's Electric Dipole Moment Using the PbF Molecule
The sequential game is a mathematical model of the interaction of multiple self-interested players in dynamic stochastic environments with limited information.  The long-term goal of this research project is to design and implement specialized
Computing Equilibria for Large Sequential Games
Music-making is universal and has been a conduit for human creativity for at least tens of thousands of years, and music plays an essential role in human social bonding, emotional communication, and entertainment. Because information technology
ARRA: MODELING MUSIC IMPROVISATION TO SUPPORT CREATIVITY IN EDUCATION AND PERFORMANCE
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).When a smooth complex surface degenerates to a singular surface with an ordinary double point there is a so called vanishing cycle: a two dimension
Exceptional vector bundles and degenerations of surfaces
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).    The plasmasphere boundary layer (PBL) is a critical region for dynamic processes in the mid-latitudes that couple the Earth's ionosphere and ma
Studies of Plasmasphere Boundary Layer with a Distributed Array of Radio Instruments
In experimental biomechanical studies, a common problem is the difficulty of conducting a large number of tests for the efficacy time course of engineering manipulation. An integrated experimental and computational molecular biomechanics model
Modeling of Endothelial Cell Adhesion Dynamics Modulated by Experimental Molecular Engineering
Collaborative Research: Analysis and Modeling of Traffic Instabilities in Congested Traffic
The City of Levelland along with the Levelland Economic Development Corporation are developing a 300 acre lot so that future tenants can have access to rail, utilities, and roads.  This will be a rail served industrial park which will provide t
Purchase furnace and wood stoves for elders
Head Start Quality Improvement to improve student/teacher ratios in classrooms, to provide teacher training and a 1/84% Cost Of Living Adjustment for staff.  Funds to be used for the benefit of children enrolled in the Head Start program in Lon
ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act.  This award was used for a one-time 1.84% COLA (cost of living allowance)  for all staff July 1, 2
ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Sections 640(a)(5) of the Head Start Act
ARRA COLA and Quality Improvement funding consistent with the provisions of Section 640 (a) (5) of the Head Start Act.? Number of children to be served ? 231 Children ?Program options offered ? Center-Based & Home-Based ?Cities or counties serv
CARBON COUNTY CHILD DEVELOPMENT PROGRAMS
Head Start 2009 ARRA COLA and QI funding.  This includes a cost-of-living increase of 1.84% for each current employee for a 12 month period after the staff returns in the fall of 2009.  Quality funding will be used for a percentage increase in
Carbon County Child Development Programs ARRA
Cost of living increase of 1.84% in the amount of $6302 and qualtiy improvement funds of $21,164 of which $10,582 will be used to replace playground equipment at the Buena Vista Site
Head Start COLA and Quality  Improvement
The Head Start ARRA Quality Improvement funding was provided in improve the Denver's Great Kids Head Start program in various ways.  A Cost of Living Allowance was provided for staff so that program salaries would remain competitive with other
Award was used to give 1.84% Cost Of Living Adjustment to all Early Head Start and Head Start Staff. Quality Improvement funds were used to ensure that compensation is adequate to attract and retain qualified staff for the programs and enhance
The Amount of ARRA funding Kids on the Move Early Head Start received allowed our program to increase its knowledge base and strengthen its resources in the area of Disability Services with the expected outcome of stronger community collaborati
FLOYD COUNTY COMMUNITY ACTION AGENCY INC
This award provides for ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistant with the provision of Section 640(a)(5) of the Head Start Act for the Head Start and/or Early Head Start Program.  Head Start promotes the
GRAND FORKS PUBLIC SCHOOL DISTRICT BUILDING AUTHORITY
This award provides for ARRA Head Start Expansion funded to serve 15 Head Start children all day.  The Expansion program provides services for low-income families, who are working or students.  Head Start promotes school readiness of low-income
This award provides for ARRA Head Start Expansion funded to serve 17 children. The Head Start program provides family centered services for low income families with young children (3-5) to promote healthy development of the children and familie
COMMUNITY PARTNERSHIP FOR CHILD DEVELOPMENT
This award provides for ARRA Head Start Expansion funded to serve 57 children. The Head Start program provides family-centered services for low-income families with preschool-aged children (3-5 years old) to promote the healthy development of t
NORTHERN CIRCLE INDIAN HOUSING AUTHORITY
This award is based on the formula allocation of the Indian Housing block Grant Program.  Northern Circle Indian Housing Authority is the recipient, as a TDHE, of an award totaling $1,562,844 which is being spent on the following housing improv
Northern Circle Indian Housing Authority ARRA Housing Improvement-Formulas-Based Award
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5)  0846505 Stein  Genetic information holds a key to rapid progress in the life sciences and medicine, yet it remains difficult to obtain because it
CAREER: Probing the Sequence and Dynamics of Single DNA Molecules Using Solid-State Nanopores, Optical Tweezers, and Binding Proteins
Historically, Langmuir circulation (LC) is characterized by pairs of parallel counter-rotating vortices oriented approximately in the downwind direction driven by the wave- and wind-driver turbulence within the upper ocean mixed layer. The high
CAREER: Parameterizations of Langmuir Turbulence in Shallow Water
'The research goal of this integrated research and educational endeavor is to advance the fundamental understanding of the behavior of interconnected systems by studying the influence of delays on their stability and performance. The proposed t
CAREER: Stability and Performance of Systems with Network-Induced Delays
The research objective of this Faculty Early Career Development (CAREER) project is to establish the relative contribution of three distinct mechanisms in improvement of damaged bone tissue mechanical properties. The three mechanisms evaluated
CAREER: Hierachies of Repair in Damaged Bone - A Role for Osteocytes
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  The primary science objective of this project is to gain a global understanding of the Kelvin-Helmholtz Instability (KHI) on Earth's magnetospher
CAREER: Effects of the Magnetosheath Properties on the Dynamics and Plasma Transport Produced by the Kelvin-Helmholtz Instability and on the Plasma Sheet Anisotropies
The central goal is to study the mesoscale self-assembly of hydrophilic materials with applications in a wide variety of fields ranging from materials science to biological studies. We aim to achieve this goal by developing simple and widely ap
CAREER: Mesoscale Self-Assembly of Hydrophilic Materials
In this CAREER project, supported by the Theoretical & Computational Chemistry Program of the Chemistry Division, Prof. Edward Valeev of the Virginia Polytechnic Institute and State University together with his students and postdoctoral workers
CAREER: Scalable explicitly correlated methods for molecular structure
The major objective of this 5-year CAREER Development project is to discover unifying principles that guide locomotor compensation and integrate these scientific principles into prosthetics and orthotics education. The research goal is anchored
ARRA: CAREER: DYNAMICAL CONTROL OF IMMEDIATE LOCOMOTOR COMPENSATIONS IN THE LEG
In this CAREER project supported by the Theoretical and Computational Chemistry Program of the Chemistry Division, Jose Gascon of the University of Connecticut will carry out research to develop accurate classical/quantum (QM/MM) computational
CAREER: Scalable Moving-Domain QM/MM Methods for the Computation of Protein Electrostatics
Language consists of an extremely complex signal, replete with information of several different types, including words (lexicon) and their smaller parts (morphology), syntactic structure (grammar), connections between input and previous input (
Career: The Role of Good-Enough Processing in Language Comprehension
The very early universe, in the first instance after its creation, was filled with a very hot and dense soup of matter, consisting of quarks, leptons and gluons. When the universe expanded and cooled, but still just milliseconds after the Big B
CAREER: NEW THEORETICAL DEVELOPMENTS IN HIGH ENERGY NUCLEAR COLLISIONS
Understanding how humans comprehend speech is an unsolved and challenging problem, in part because of the many-to-many mapping between the acoustical properties of the speech signal (i.e., frequency, timing, and amplitude) and the words perceiv
CAREER: The Role of Prosody in Word Segmentation and Lexical Access
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).The purpose of this project is threefold: development and analysis of fast, randomized, easily parallelizable algorithms, study of average behavior
CAREER:  Synergistic interactions between Numerical Linear Algebra and  Stochastic Eigenanalysis (Random Matrix Theory)
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). In this project supported by the Experimental Physical Chemistry Program, Professor Alexander N. Tarnovsky of Bowling Green State University will
CAREER: Monitoring ultrafast excited-state selective dynamics, bond rupture, and rearrangement of small polyatomic molecules in solution
Other Scientific and Technical Consulting Services
An award has been made to Washington State University for a collaborative effort with Western Washington University focused on moth biodiversity in the Pacific Northwest. This project will database the holdings of macro-moths in the James Entom
Collaborative Research: Collection Enhancement and Biodiversity Informatics for Pacific Northwest Macromoths
Professors James D. Batteas of Texas A&M and Charles M. Drain of Hunter College of CUNY are supported by the Analytical and Surface Chemistry Program in the Division of Chemistry to systematically design and synthesize a series of porphyrin and
COLLABORATIVE RESEARCH: CONDUCTION IN CONFINED MOLECULAR ASSEMBLIES
In this project the PI will study the physical principles of viral genome packaging using phi29 as a model system. The study will use previously developed technique based on optical tweezers for real time visualization of viral packaging proces
Dynamics and Energetics of Viral DNA Packaging and Ejection
COLLABORATIVE RESEARCH: INFLUENCE OF TEMPERATURE AND ACIDIFICATION ON THE DYNAMICS OF CORAL CO-INFECTION AND RESISTANCE
Allows us to improve the living conditions of elderly and handicapped persons.
This is one of 50 Physics REU (Research Experience for Undergraduates)programs in the country.  The money is aimed at supporting students coming from institutions around the country to be mentored by faculty in the Physics & Astronomy Departmen
REU SITE:  FRONTIER PHYSICS AND ASTRONOMY RESEARCH WITH TECHNICAL PRESENTATIONS
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).    Recent research has established that much and perhaps most of the interannual to interdecadal variation of tropical cyclone activity integrated
Collaborative Research Environmental control of Tropical Cyclone Activity
The Kuroshio brings warm waters northward in an intense current along the western boundary of the North Pacific. The current departs the Japanese coast to flow eastward as the Kuroshio Extension. This strong jet creates a front between warm sub
COLLABORATIVE RESEARCH: KUROSHIO EXTENSION SYSTEM STUDY (KESS) ANALYSIS-MEOSCALE PROCESSES
To recruit eight undergraduates to participate in hands-on physics research with various research groups on campus for ten weeks in the summers of 2009, 2010 and 2011.
Florida State University is awarded a collaborative grant to create a distributed information system that combines digital image repositories, biological collection management system and ontology management systems.  The interoperability of the
Collaborative Research: Data Integration for Repository Services in Biodiversity Informatics
Two groups of migrants, aging baby boomers and Latino immigrants, are converging on rural America. Together, these groups will significantly transform their destination communities in the coming decades. While these migration streams have each
RUI: Collaborative Research: Linked Migration and Changing Labor Markets in the Rural United States
Collaborative Research: A 3D seismic investigation of the transition to seismogenic behavior along the southern Costa Rica subduction zone
Self-control problems are at the core of many of the public policy challenges facing the United States. Examples include obesity, addiction, and low levels of savings. Not surprisingly, given its importance, the problem of self-control has bee
The Neuroeconomics of Self-Control in Dieting Populations
NATURAL RESOURCES, SOUTH CAROLINA DEPARTMENT OF
This REU Site at the South Carolina Department of Natural Resources Marine Resources Research Institute offers a ten week research program for undergraduate minority students in the marine and environmental science fields. Students will be prov
This project will establish an REU site in nanometerials at the University of Nebraska-Lincoln, sponsored by the Nebraska Center for Materials and Nanoscience. The primary objectives will be to (1) create an atmosphere within which students can
REU Site:  Undergraduate Research Opportunities in Nanomaterials and Nanoscience at the University of Nebraska-Lincoln
Undergraduate students and K-12 teachers in University of Texas Environmental Science Institute's combined REU/RET program will work in the research groups of faculty mentors working on scientific topics related to The Integrated Science of Glo
REU Site: The Integrated Science of Global Change and Its Impacts
This award to the University of Alaska Southeast (UAS) is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). UAS will conduct an REU Site research program for undergraduates during the summers of 2009, 2011 and
REU Site in Marine and Coastal Ecology in Alaska
The Experimental Physical Chemistry Program supports Professor Alexander Scheeline of the University of Illinois at Urbana-Champaign to develop a levitated drop reactor to study the nonlinear reaction dynamics of myeloperoxidase, an enzyme foun
SGER: Development of Levitated Drop Reactor for Chemical, Enzyme and Nonlinear Dynamics
* Objectives.  We hypothesize that acidic sulfates will have a significant impact on SOA formation in the atmosphere via heterogeneous reactions forming nonvolatile organics such as heterogeneous acid-catalyzed reaction products (HAC-P) and org
Characterization of Secondary Organic Aerosol Exposed to Acidic Sulfate Aerosols Using Aerosol Bulk-phase Analytical Techniques
The following five projects will be carried out during the proposed five-year support period. 1. Simultaneous measurements of close and distant electromagnetic signatures of lightning for (a) testing the validity of lightning return-stroke mode
Lightning:  Electromagnetic Environment and Source Parameters
Chalcogenide Phase Change (PC) materials are of interest due to their widespread application in high density PC optical recording and random access memory (PCRAM) devices. The operation of these devices involves a complex interaction of tempera
Thermal Characterization of Nanoengineered Chalcogenide Materials for Phase-Change Memory
The goal of this research is to provide a scientific basis for the development of a new class of materials for reversible and high capacity storage of hydrogen in nanostructured metal hydrides at moderate temperature and pressure.
Hydrogenation/Dehydrogenation in Novel Pd-Coated Mg Nanoblades
Award description. Project summary: Growing recognition of the importance of complex microbial communities and biofilms in engineered systems for environmental, industrial, medicinal, agricultural and municipal applications has created a demand
Collaborative Research: New medium for DNA separtation of microbial communities
Intellectual merit   Protein therapeutics (biopharmaceuticals) are increasingly being used for the treatment of a variety of diseases. Over 165 biopharmaceuticals are currently on the market and hundreds more are in development, representing mo
ARRA Engineering the Unfolded Protein Response for Improved Protein Production
'International Research Experience for Students: U.S.-Ukraine Collaboration on Discrete and Nondifferentiable Optimization  This US-Ukraine project provides US undergraduate and graduate students opportunities to conduct research at the Glushko
IRES: International Experience for Students: U.S.-Ukraine Collaboration on Discrete and Nondifferentiable Optimization
The PI proposes to apply a state of the art fluorescent index matching technique to measure the three dimensional positions of particles in the bulk to investigate the elastic and plastic response of a dense granular system undergoing cyclic sh
Structural Rearrangements and Transport Properties of Cyclically Sheard Granular Packings
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).    This NSF award by the Chemical and Biological Separations program supports work by Professor Jongyoon Han at the Massachusetts Institute of Tec
Science and Engineering of Ion Concentration Polariztion and Enhanced Electrokinetic Flow
'Most cells generate intracellular forces that are transmitted to, and countered by, forces in the extracellular matrix. This mechanical force balance is necessary for maintaining both mechanical and biochemical cell equilibrium, i.e. homeostas
Theoretical and Experimental Studies of Cell Reorganization on Deformable Materials
The design of clinically effective materials for the surgical repair of ruptured ligaments remains a challenging biomedical engineering problem. Currently, tissue grafts from the patient and cadaveric sources are the only clinically effective m
Intellectual Merit The present proposal is to explore new anode materials that will allow solid oxide fuel cells (SOFCs) to work directly with a range of practical fuels, including hydrocarbons, gasified biomass, or coal. SOFCs are of particula
Fundamentals and Implementation of Oxide Anodes for Solid Oxide Fuel Cells
The goal of this research is to study how lipophilic chemicals penetrate through the outermost layer of human skin, which is called the stratum corneum. The stratum corneum is a thin (20 to 40 um thick), composite membrane containing layers of
Using Pulsed-Field Gradient Spin-Echo NMR to Determine Permeation Mechanisms in Human Stratum Corneum
Gene therapy relies on the development of vectors that can carry therapeutic genes to target cells. Non-viral vectors can avoid the safety issue inherent to the viruses, but lack the capability of recognizing target cells and have low efficienc
Gene delivery vectors inspired from the structure and assembly process of target-recognizing phage
'This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).'  The real world inspires much of computer graphics and visualization research. In our work, we seek to acquire models directly from the real wor
II-NEW: THE UTAH ACQUISITION AND RAPID PROTOTYPING LABORATORY
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). It will provide funds to work on the Pierre Auger Observatory in Malargue, Argentina. The Observatory is the world's largest detector for 'ultra-h
ARRA Data Analysis and Atmospheric Monitoring for the Pierre Auger Observatory
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). This award extends the Stanford LIGO group's ongoing program on advanced gravitational wave detectors to address risk mitigation for Advanced LIGO
The Stanford Advanced Gravitational Wave Detector Research Program
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  The inert (or 'noble') gases are so named because they generally do not interact much with other materials. Like many other elements, however, ce
HYPERPOLARIZED 129XE: PHYSICS AND APPLICATIONS
The objective of this project is to investigate a new light pattern as a possible solution to the 'addressability problem' of neutral atom quantum computing. Quantum computers are theoretical devices that exploit the fundamental rules of quantu
RUI: Investigation of Atomic Dipole Traps Created by Diffraction of Laser Light for Use in Quantum Computing
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). This award supports the PI's group to (I) work on searches for unmodeled bursts of gravitational waves in the incoming LIGO science run and (II) s
RUI: Proposal to Conduct Selected Searches and for Gravitational Wave Bursts and Young's Modulus Measurements of LIGO Mirror's Coatings.
Few-body collisions are playing an increasingly important role in experiments on ultracold quantum gases. This work addresses some of the most important outstanding questions about such collisions: What happens when three bodies collide in the
A theoretical investigation of few-body systems
The object of the project is 1) to investigate orientation and vibration dependent multiphoton ionization (MPI) and high harmonic generation (HHG) for the potential application of monitoring molecular structure and dynamics with ultrafast and h
Theroetical investigation of molecule-intense laser interactions using quantum chemical approaches.
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).Funds are provided to deploy a single, strategically placed mooring in the core of the western Arctic boundary current east of Barrow Canyon, which
Collaborative Proposal: An Interdisciplinary Monitoring Mooring in the Western  Arctic Boundary Current: Climatic Forcing and Ecosystem Response
The Circumpolar Active Layer Monitoring Network--CALM III (2009-2014): Long-term Observations on the Climate-Active Layer-Permafrost System  Maintain long-term observations on climate/permafrost/active-layer system on the network of circumarcti
The Circumpolar Active Layer Monitoring Network--CALM III (2009-2014): Long-term Observations on the Climate-Active Layer-Permafrost System
This award supports the purchase of a new laser to replace the current laser in the lidar at Eureka, Nunavut, Canada. The installation of the new laser will improve instrument reliability and data quality of an observing system that has been op
ARRA A Replacement Laser for the Arctic High Spectral Resolution Lidar
The overarching goal of this renewal project is to maintain the existing ITEX AON and increase the applicability of the data collected to the greater scientific community. The International Tundra Experiment (ITEX) network has collected data on
Arctic Observing Networks: Collaborative Research: Sustaining and amplifying the ITEX AON through automation and increased interdisciplinarity of observation
Objectives This study will seek to demonstrate experimentally the existence of new types of magnetically tunable optical band gaps recently predicted by the PIs. The project will design, fabricate and characterize functional photonic crystal st
Degenerate Bandgaps in Magneto-Photonic Crystals and Magneto-Photonic Crystal Biochemical Sensors
This award will support the continued implementation of the Bering Sea Sub-Network (BSSN), a regional initiative of community-based organizations in Western Alaska and Northeast Russia. The 'Intellectual Merit' of BSSN lies in its operation as
Bering Sea Sub Network: A Distributed Human Sensor Array to Detect Arctic Environmental Change
Evaluation and Monitoring of Long Valley Caldera volcanic activity, including associated seismic and geologic hazards. Contract of $76,857 to two part-time CGS staff (combined contracts) to assist in project from July 1, 2009 to June 30, 2010.
Geophysical Surveying and Mapping Services
US-89; Townsend Rd to Fernwood Rd n/o FLAGSTAFF
SAN BERNARDINO NATIONAL FOREST ASSOCIATION
The purpose of the award is to provide opportunities for job training, personal development, conservation service, and natural resource appreciation while at the same time accomplishing work that contributes and benefits to public lands.
Funds will be used to support Teachers, Family Service Providers, Teaching Assistants, Health Coordinators and Educational Coordinators with ongoing professional development related to obtaining BA qualifications, ECE additional course work and
Cost of Living adjustment increase of 1.84% for Early Head Start and Head Start staff.  Quality improvement funds for a playground, staff training and classroom equipment and supplies.  Completion of project is expected to result in improved pr
This action awards a cost-of living increase of 1.84% in the amount of $43,585 for Head Start Employees.  Our program employs 70 employees and provides services to 392 children and their families in a geographic area that covers 15,000 square m
ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the providsions of Section 640(a)(5) of the Head Start Act
This award provides for ARRA Cost of Living Adjustment of 1.84%; and Quality Improvement Funding for computers; one new employee position; to extend hours of one position; nutrition, health, and safety measures for children, families, and staff
ARRA COLA: Funds will be used to award a cost of living adjustment of 1.84% effective July 1, 2009. This increase will be awarded to all staff and will be paid out over the next year on a quarterly basis. The DDI VANTAGE, Inc. Early Head Start
ARRA: Head Start Expansion Grant -  To Promote school readiness of Head Start Children and assist their families. To reduce the waiting list for needy Head Start families. - To Serve 32 additional Head Start children that began January 11, 2010
Native American Housing Block Grant, Formula - New Construction, Aquisition, Rehabilitation including energy efficiency and conservation, and infrastructure development
Nanwalek Rental Units, Port Graham Single Family Home, Seward Rental Renovations
Native American Housing Block Grants ( Formula) Recovery Act Funded
COLORADO RIVER RESIDENTIAL & MANAGEMENT CORP
Native American Housing Block Grant Formula-New construction, acquisition, rehabilitation including energy efficiency and conservation and infrastructure development.
Modernization of 1937 housing stock units on the Colorado River Indian Tribes Reservation.
QUECHAN TRIBAL DESIGNATED HOUSING ENTITY
Funds are to be used for housing rehabilitation activities.     Expected outcomes include the following: Improve quality of substandard units  Improve energy efficiency Expected Results:  Replace 13 A/C units with new high efficiency 2 speed 16
HOUSING AUTHORITY OF THE IOWA TRIBE OF KANSAS & NEBRASKA INC
PLEASANT POINT PASSAMAQUODDY RESERVATION HOUSING AUTHORITY
All funds to be used to reduce energy costs at rental units.  Forty-three units will have new energy efficient windows and doors installed.  Eight furnaces will be updated to lower energy costs.  Intended outcome is to decrease energy costs to
Native American Housing Block Grant Formula-American Recovery and Reinvestment Act of 2009
AQUINNAH WAMPANOAG TRIBAL HOUSING AUTHORITY
Native American Block Grant Formula - NAHASDA elibible activities including rehabilitation of affordable housing, administration and planning, and improvement to achieve greater efficiency  and mold remediation.
Replacing Existing Furnaces and Hot water heaters with new energy efficiency ones.
Native American Housing Block Grant Formula - Acquisition Purchase of modular homes
New Wave Homes purchased 4 new homeownership units to be utilied for tribal members a
American Recovery and Reinvestment Act of 2009 Indian Housing Block Grant Formula Allocated Amount
Rehabilitation Assistance to Existing Homeownership Units and Modernization of 1937 Act Housing
Down Payment Assistance - Buffalo Range Subdivision
This project's objective is to identify the source of oxidized iron minerals in the 3.26-billion-year-old Manzimnyama Jaspillite Member of South Africa, one of the oldest well-preserved examples of a class of rocks called banded iron formations
MECHANISMS OF IRON OXIDATION DURING BANDED IRON FORMATION DEPOSITION 3.26 BILLON YEARS AGO
This award will allow structural biologists at the University of Oklahoma-Norman campus to establish an automated Macromolecular Crystallization Core Facility that will enable researchers throughout the State and regionally to accelerate the pa
MRI: Acquisition of Robotics Instrumentation for Crystallization of Biomacromolecules
A current challenge for genetics and genomics research is discovering DNA sequences that alter the expression of genes operating during development and various physiological processes. This project will develop the statistical method of structu
A BAYESIAN FRAMEWORK FOR ANALYZING GENETIC AND GENE EXPRESSION ARCHITECTURE OF COMPLEX PHENOTYPES
The acquisition and use of this molecular imaging instrument will enable new research directions and educational opportunities and programs that will significantly contribute to the intellectual base of knowledge in these disparate but unified
MRI: Acquisition of a Molecular Imaging Instrument for Dynamic Material and Biological Systems
This research project is the US contribution to a nine-member, seven-nation research study titled, 'Colony, Empire, Environment: A Comparative International History of Twentieth Century Arctic Science” (CEE). One of seven research teams funde
Constituting the Artic Environment: How US Military Patronage After World War II Influenced the Environmental Sciences in the Far North
Technical Abstract  This MRI proposal by Brown University requests support for the acquisition of an FEI Tecnai S20 transmission electron microscope (TEM) to serve the nanoscale imaging and micro/nano-characterization needs of the local researc
MRI: Acquisition of a Tecnai TS 20 Field Emitter Transmission Electron Microscope
This MRI proposal requests to acquire a high resolution scanning electron microscope (HRSEM) for interdisciplinary research and education at the University of South Florida (USF). The HRSEM instrument with ultrahigh-resolution and optimized ana
MRI: Acquisition of an Ultrahigh Analytical Thermal Field Emission Scanning Electron Microscope for Research and Education
This award is for the acquisition of an imaging X-ray photoelectron spectroscopy (XPS) microprobe surface analysis system to support diverse multi-departmental program at University of Alabama at Birmingham (UAB) in nanostructured, compositiona
MRI ACQUISITION OF IMAGING X-RAY PHOTOELECTRON SPECTROSCOPY SYSTEM FOR INTERDISCIPLINARY RESEARCH AND EDUCATION IN MULTI-SCALE MATERIALS
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). The Marquette University computational grid (MUGrid) brings together a diverse team of investigators from mathematics, statistics, computer scienc
MRI: Acquisition of a Parallel Computing Cluster and Storage for the Marquette University Grid (MUGrid)
A grant has been awarded by NSF to the University of Southern Mississippi for the purchase of instrumentation to expand faculty resources for ecological research and to improve student education and training.  This instrumentation includes a CH
MRI:  Acquisition of instrumentation to strengthen ecological research and education at The Univers
Advanced optical techniques (such as PIV, LIF and LDV) represent the most well-resolved and accurate means of experimentally documenting the physics of flows, yet there exist a wealth of practical complex flows spanning many fields of science a
MRI: Development of a Large-Scale Refractive-Index Matched Flow Facility
With this award from the Major Research Instrumentation (MRI) program, Mark Young and colleagues Vicki Grassian, and Paul Kleiber from the University of Iowa will develop a single particle aerosol mass spectrometer. The proposed aerosol mass sp
MRI: Development of a Single Particle Mass Spectrometer for Field and Laboratory Studies of the Environmental Impact of Atmospheric Aerosols and Engineered Nanoparticles
Observing time on the world's largest telescopes is a very valuable commodity. Any scheme that can enhance their efficiency pays significant dividends in the number of scientific research programs that can be undertaken and in the associated co
The Michigan/Magellan Fiber System (M2FS): An MRI Development Proposal
This project, acquiring High Performance Computing (HPC) instrumentation, aims to support much larger and more complex problems in science and engineering (especially for data intensive applications), add greater physical fidelity to existing m
MRI/Acq.: ISTeC High Performance Computing Infrastructure for Science and Eng Research
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).Recent progress in ultrafast laser technology has enabled new spectroscopies for probing matter in fundamentally new optical regimes with regard to
Development of an Active and Passive Phase Stabilized Femtosecond Laser System for Spatio-Temporal Imaging and Frequency Metrology in the Infrared
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5)  This award will fund the acquisition of a PowerWall-Based Virtual Reality (VR) system to enable the research and teaching in virtual prototyping a
MRI:  Acquisition of a PowerWall Virtual Reality System for Enabling Research/Teaching in Virtual Prototyping
Proposal #: NSF MRI 09-23456  PI(s): Lei, Hansheng; Benacquista, Matthew J.; Figueroa, Andres; Iglesias, Juan R.; Mukherjee, Soma  Institution: University of Texas - Brownsville  Title: MRI/Acquisition: FUTURO: A Data Intensive and High Perform
MRI/Acquisition: FUTURO: A Data Intensive and High Performance Computing Cluster for Integrated Research & Education
This project, developing a dense wavelength division multiplexing (DWDM) multi-mode switching platform instrument, supports telesurgery, telemedicine, and heterogeneous applications by allowing different types of messages within an application
MRI: Development of Reconfigurable DWDM Multi-Mode Switching Platform for Supporting Telesurgery Telemedicine and Heterogeneous Applications
METHODIST HOSPITAL RESEARCH INSTITUTE, THE
Our overarching goal is to develop mobileWARP as a community platform for mobile wireless research and education in next-generation networks. We envision mobileWARP devices to achieve data rates of 100+ Mbps, support interactive real-time user
Collaborative Research: MRI: Development of mobileWARP - A Platform for Next-Generation Wireless Networks and Mobile Applications
New revolutionary technologies have been developed enabling scientists with the ability to rapidly determine the sequence of large amounts of DNA. This will allow scientists in nearly all biological disciplines to rapidly move forward on projec
MRI: Acquisition of Solexa Genome Analyzer To Enable Collaborative Molecular, Environmental, and Computational Research
This project, building a Scalable Energy Efficient Datacenter (SEED), develops an integrated solution that encompasses physical layer hardware, protocols, and topologies that can provide the expected size and performance scaling for future data
MRI: Development of a Scalable Energy Efficient Datacenter (SEED)
SBIR Phase II: Pneumatic Energy Storage with Staged Hydraulic Conversion for Low Specific Cost Renewables Support
This collaborative research project is being undertaken by Dr. Nathaniel J. Dominy, University of California Santa Cruz, and Dr. Salima Ikram, American University of Cairo, Egypt, to analyze isotope ratios of mummified baboons and to compare th
US Egypt Cooperative Research: Baboons, stable isotopes, and the mystery of Punt
The past decade has seen a profound shift in our understanding of the bacterial cell. It is now clear that the three-dimensional organization of the cell is an integral component of the function of cellular regulatory pathways. The bacterial ce
Molecular Mechanisms of Dynamic Protein Localization in the Bacterial Cell
With this award from the Chemistry Research Instrumentation and Facilities: Instrument Development (CRIF:ID) program, Marcos Dantus and his research group from Michigan State University will develop a phase and polarization modulated ultrafast
Development of a phase and polarization modulated ultrafast laser source for nonlinear optical imaging and molecular identification
Nationally visible cases of convicted criminals who lapsed back into criminal activity following their release into the community have prompted state and federal legislators and local communities to focus on the public safety risk posed by offe
Collaborative Research: Spatial Analytical Framework for Examining Community Risk Issues over Space and Time
With this award from the Chemistry Research Instrumentation and Facilities: Instrument Development (CRIF:ID) program, the research group at Oregon State University will develop a novel electromagnetostatic (EMS) electron capture dissociation (E
Radio Frequency Free Electromagnetostatic Dissociation Cell for Tandem Mass Spectrometry
Professors Jeffrey Schwartz and Steven L. Bernasek of Princeton University are supported by the Analytical and Surface Chemistry Program in the Division of Chemistry to conduct research in collaboration with Professor Marc Tornow of Braunschwei
International Collaboration in Chemistry: A New Molecular Architecture for Organic Electronics
SBIR Phase II: Water and Food Analysis by Non-Uniform Electroosmotic flow
Water and Food Analysis by Non-Uniform Electroosmotic flow
The Organic and Macromolecular Chemistry Program in the Chemistry Division at the National Science Foundation supports a proposal from Professor Fraser J. Stoddart of Northwestern University. This proposal, submitted in response to solicitation
International Collaboration in Chemistry: Structural Mechanostereochemistry of Mechanically Interlocked Polymers
SBIR Phase II: Ultrafast spintronic devices based on magnetic tunnel junctions using magnesium oxide (MgO) tunnel barriers
Development of ultrafast spintronic devices based on MTJs using MgO tunnel barrier
This Small Business Innovation Research (SBIR) Phase II project will extend the successful findings of Phase I of the project to investigate the technical feasibility of an innovative emergency notification system that delivers emergency alerts
SBIR Phase II:   An Emergency Notification System for Delivering Geo-Targeted Information-Rich Web Alerts.
This award is funded under the American Recovery and Reinvestment Act of 2009 (public Law 111-5). It supports a workshop at the University of Houston, built around the theme, Energy Capitals: Local Impact, Global Influence. The workshop brings
Energy Capitals: Local Impact, Global Influence
The proposed research activities focus on the mechanisms that impact memory for content in a non-dominant language, The experiments will examine memory performance of Spanish-English bilinguals in their dominant and non-dominant languages, as w
A Cognitive Study of Bilingual Proficieency and Memory on the U.S. Mexico Border
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).The objective of this research is the development of new generalized integrated imaging and communication technologies making use of recent studies
Integrated Space-time Strategies for Imaging and Communication in Complex Environments
'The project proposes to investigate a new type of amplifying coupled-resonator optical waveguide (CROW). The CROW is to be realized in a waveguide geometry with individual resonators formed by grating ''defects''. The waveguide will be fabric
Current-Pumped, Amplifying, Slow Light Waveguides in Hybrid Si/III-V Platforms
We develop an electrically pumped microcavity exciton-polariton laser as a novel coherent light source based on the exotic quantum nature, Bose-Einstein Condensation (BEC) of microcavity exciton-polaritons. In a monolithic semiconductor structu
Electrically Driven Microcavity Exciton-Polariton Lasers
We propose a new paradigm in antenna design and development that can lead to very low-loss radiating/receiving devices that are mechanically stretchable, flexible, and 'self-healing'. These properties offer a wide spectrum of possibilities in r
Stretchable, Tunable, Self-Healing Micro-Fluidic Antennas
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5)  Objective: The objective of this program is to develop a new framework for studying distributed inference with dependent observations. A broad ran
A Unifying Framework for Distributed Inference in Networked Systems
Our specific research objectives are therefore as follows: 1. Develop and optimize a theoretically justifiable framework for incremental learning of new data a. whose underlying distribution may experience a wide spectrum of drift scenarios, su
AIS: Incremental Learning from Unbalanced Data in Nonstationary Environments
Collaborative Research with Carnegie Mellon University, Jet Propulsion Laboratory, and the University of Pittsburgh.  The goal of the proposed Expedition is to develop the next generation of model-checking and abstract-interpreation technology
Collaborative Research: Next-Generation Model Checking and Abstract Interpretation with a Focus on Embedded Control and Systems Biology
Novel Experimental and Theoretical Approaches to Understand Biomechanics of Atherosclerotic Plaque Rupture Atherosclerotic plaque rupture is the leading cause of acute cardiovascular events such as heart attack and stroke. While studies of plaq
Novel Experimental and Theoretical Approaches to Understand Biomechanics of Atherosclerotic Plaque Rupture
The research objective of this BRIGE award is to develop new connection details utilizing the superior compression, bending, and torsion properties of hollow structural section (HSS) beam and column members for low to mid-rise steel frames in a
BRIGE: Innovative Connection Design for Enhanced Seismic Performance of Low to Mid-Rise Steel Frames
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). The award supports undergraduate students from Southeastern Louisiana University and other southeastern EPScoR state universities for seven weeks
IRES: Interdisciplinary Research on Characterization of Mechanical Properties of Materials
An emerging area of alternative fuels has great significance for the economy, transportation and power generation systems. In the global, just-in-time economy, American competitiveness and innovation require an affordable, diverse, stable, and
BRIDGE: Ignition, Burning Rate, Chemistry, and Transport Properties of Alternative Fuels
Oceanic core complexes (OCC) expose intrusive mafic rocks and lenses of mantle ultramafic rock, that are controlled by long-lived detachment faulting within the axial zone of a spreading center. The PI will analyze existing MCS OBS data at Atla
Lateral Variations in Seismic Structure of Atlantis Massif Oceanic Core Complex
This award funds a workshop focused on developing a research plan for work in the Soledad Basin, a high sedimentation rate anoxic basin with laminated sediments off Baja California. Topics covered will include 1) the 20th century warming of the
Hydrographic and sediment-trap monitoring of anoxic Soledad Basin off Baja California for enhanced climate reconstructions: An interdiscplinary planning workshop
The research objective of this award is to develop a methodology for reliability and safety factor assessment of suspension bridge cables over time using real-time measurements from sensors installed inside the cables. Today, small-scale sensor
Reliability and Safety of Suspension Bridge Cables Using Continuous Health Monitoring Data
The proposed research designs new biomaterials to guide the long-range directional migration of attached mammalian cells in three dimensions. Like one-way signs, the patterned microarrays and/or microchannels impose directionality on cell movem
Design of Biomaterials for Directed Cell Assembly
Collaborative Research: Serpentinization and cycling of B, Nd and Sr in submarine hydrothermal systems: An experimental study on the effects of pH and temperature Project Summary Intellectual Merit: The serpentinized ultramafic oceanic lithosph
Collaborative Research: Serpentinization and cycling of B, Nd and Sr in submarine hydrothermal systems: An experimental study on the effects of pH and temperature
There is a growing body of literature suggesting that cells use mechanical forces to transmit information and guide the assembly of  multi-cellular structures. For example, during development, wound healing, and the creation of engineered tissu
(ARRA) Biomechanical regulation of cellular signaling and organization
Arts and the American Recovery and Reinvestment Act of 2009
The inert nature of the noble gases makes them ideally suited to trace the volatile evolution on Earth. In particular, the Iodine-Xenon and Plutonium-Uranium-Xenon radioactive decay systems are the only ones that can provide constraints on the
Noble gas studies along ultraslow spreading Southwest Indian Ridge: Constraining magmatic degassing processes and the origin and lengthscale of mantle hetereogenities
to military uniforms and shelters to portable consumer electronics, the impact of a textile capable of generating electricity from the sun that could be incorporated into existing products and materials in a flexible, fabric platform could be
While the number of women receiving advanced degrees in the geosciences has been rising, the face of scientific leaders in academia remains dominantly male. Through the establishment of infrastructure to support the Earth Science Women's Networ
Partnerships for Adaptation, Implementation, and Dissemination (PAID): Collaborative Research - Career Advancement for Women through the Earth Science Women's Network (ESWN)
Scholars program. The PI will promote women and minorities in his program (of which he has been very successful in the past).
Acquisition of a Continuous Flow Isotope Ratio Mass Analyzer for Tropical Paleoclimatology
This award will provide support for a 400 electrode resistivity data collection system. It will be fitted with 2 control units (one field and one laboratory), electric addressing cards for the electrodes, field installation equipment and servic
Acquisition of an Electrical Resistivity System to Monitor Hydrologic Impacts of Climate and Land Use Changes and to Image Subsurface Transport and Density Driven Flow
This Small Business Technology Transfer Phase I project will develop a multifunctional graphene-platinum composite for hydrogen fuel cells. High performance fuel cells currently have inefficient catalyst utilization due to limited contact betwe
STTR Phase I: Graphene-Platinum Composite for Hydrogen Fuel Cells
This STTR Phase I project focuses on the synthesis and delivery of nanoparticles for determination of the progression of cancer and provides treatment options.
STTR Phase I: Intelligent Low-Toxicity Nanoparticles for Cancer Diagnosis and Treatment
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  The objective of this project is to identify major sources and physico-chemical processes that produce secondary organic aerosol (SOA) in a pollu
ARRA: COLLABORATIVE RESEARCH: INVESTIGATING SECONDRY ORGANIC AEROSOL (SOA) FORMATION IN CENTRAL LOS ANGELES FOR RESEARCH AT THE NEXUS OF AIR QUALITY AND CLIMATE CHANGE (CALNEX 2010)
The objective of this research is to develop truly intelligent, automated driving through a new paradigm that tightly integrates probabilistic perception and deterministic planning in a formal, verifiable framework. The interdisciplinary approa
CPS: MEDIUM: TIGHTLY INTEGRATED PERCEPTION AND PLANNING IN INTELLIGENT ROBOTICS
This proposal focuses on laboratory measurements aimed at elucidating the molecular orientation of catalytically relevant hydrocarbons at oxide surfaces. The PI will determine the molecular orientation and distributions of common saturated and
Olefins at the Surfaces of Transparent Oxides Studied with Coherent Vibrational Spectroscopy
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).    The objective of this research is the development of methods for the control of energy flow in buildings, as enabled by cyber infrastructure.
CPS:Medium:Cyber-Enabled Efficient Energy Management of Structures (CEEMS)
FORT WORTH SYMPHONY ORCHESTRA ASSOCIATION
Arts and the American Recovery & Reinvestment  Act of 2009
To support the preservation of jobs threatened by declines in philanthropic and other support during the current economic downturn.
Biomaterial-based arterial reconstruction is an effective approach for the treatment of atherosclerosis, the leading cause of human death. However, biomaterials induce thrombosis and intimal hyperplasia, vascular disorders contributing to the f
Engineering Enhancement of Endothelial Cell Retention on Arterial Substitutes
Driven molecular transport around active nanostructures, such as functionalized graphene nanopores, internally-excited polarizable nanotubes and novel molecular nanodevices is an important area to study. The research objectives of the PIs are t
Multiscale Modeling of Molecular Transport
To support the preservation of jobs that are threatened by declines in philanthropic and other support during the current economic downturn
To support the preservation of jobs that are threatened by declines in philanthropic and other support during the current economic downtown, as described in our application (A09-904907) and the approved project budget.
Arts and American Recovery & Reinvestment Act of 2009
Low-level jets are streams of fast-moving air in the lower troposphere. Both northerly (N-LLJs) and southerly (S-LLJs) low-level jets occur frequently in the central United States and have a significant impact on regional weather and climate, p
Collaborative Research: Toward an Improved Understanding of the Characteristics, Processes, and Impacts of Northerly and Southerly Low-Level Jets in the Central United States
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). The objective of this research award is to expand the sphere of application of impulsive control, and importantly, translate impulsive control fro
Impulsive Control of Under-Actuated Dynamical Systems
Fairness and the Provision of Public Goods Project Summary The proposed research tests a theory of fairness perceptions in social dilemma contexts. People face social dilemmas every day, such as weighing the temptation to cheat on taxes or to t
Fairness and the Provision of Public Goods
Rising demand for electrical energy and the limitations and pollution associated with fossil fuels are creating a need for better grid-connected solar photovoltaic (PV) systems.  Presently, variations among PV cells and differences in how much
Collaborative Research: Stacked Controlled-Cell Power Conversion Architecture for Grid-Connected Photovoltaic Systems
Over all Purpose: Conduct research activities to develop a novel hypergolic fuel detector using thermoelectric properties of graphene and other nanostructure carbon materials. This type of sensors can be used in aerospace and other applications
Collaborative Research: Single Walled Nanotubes and Graphene based multiplexed Sensors for Hypergolic fuel detection
This project will support the development of middleware that will enable numerical models to be run on commercial compute farms via cloud computing and exploited in ongoing and future classroom educational activities.    The intellectual merit
Cloud-computing infrastructure and technology for education (C.I.T.E)
Title: Upgrading of Shared Computing Equipment in Geophysics                    Granted funds will support upgrade of compute facilities at the Institute for Geophysics and Planetary Physics (IGPP) at the Scripps Institution of Oceanography. Up
Upgrading of Shared Computing Equipment in Geophysics
Intellectual Merit The PI?s long-term research goal is to develop a novel microbial consortium system for efficient and robust production of advanced biofuels from renewable lignincellulosic feedstocks. Her current focus is on the production of
BRIGE: Towards Efficient Production of Next-Generation Cellulosic Biofuels: A Synthetic Microbial Consortia Approach
Rising atmospheric carbon dioxide concentrations over the past two centuries have led to increasing carbon dioxide uptake by the oceans. This process, which is decreasing the pH of the upper ocean, is reducing oceanic carbonate ion concentratio
Development of Methods for Direct Determinations of Carbonate Ion Concentrations in Seawater
Over large scales encompassing heterogeneous conditions, biogeochemical mechanisms act to achieve a stoichiometric balance between nitrogen and phosphorus. Locally, however, imbalances can develop. The Laurentian Great Lakes are a vast freshwat
Collaborative Research: Sources and Sinks of Stoichiometrically Imbalanced Nitrate in the Laurentian Great Lakes
Through research in the past two decades, the science community has seen a revolution in the understanding of marine microbial diversity. Molecular sequencing has revealed several previously unknown major groups of Bacteria and Archaea, yet tot
Carbon Isotopic Heterogeneity in Modern Bacterioplankton: Model Systems for Understanding Paleoenvironmental Signatures
This is an International Research Experience for Students (IRES) award to U.S. P.I. Paul Benkeser, Georgia Institute of Technology. This award will enable 8 U.S. undergraduate students from the Biomedical Engineering Partnership Program to gain
ARRA: INTERNATIONAL: US-CHINA UNDERGRADUATE RESEARCH EXPERIENCE IN BIOMEDICAL ENGINEERING
of earthquake effects ranging from severe soil liquefaction to massive rock avalanches occurred. The work draws on the expertise of a multidisciplinary, multiple-institution team with collective expertise in geotechnical earthquake engineering
Collaborative Research: The M8.0 Pisco Peru Earthquake - A Benchmark Ground Failure Event for Remote Sensing and Data Archiving
Washington State University Sloan Hall 101
One emerging alternative to improving the state of inadequate, or decaying, infrastructure in urban environments, which does not involve a perpetuation of large scale, costly systems, is an approach known as low impact development (LID). LID in
Quantifying the Fundamental Behavior of Green Roofs in an Urban Environment
A large number of modern physical and biological structures and phenomena require tools to ?see? below the surfaces but non-destructively and with nanoscale resolution. This need is particularly critical in soft/frqgile cellular/sub-cellular pr
Implementation of Fluidic-Scanning Near Field Ultrasound Holography with Integrated Electronic Detection for Nano-Bio-Mechanics
The PI will spend the academic year 2009-2010 in the Climate Group in the Geophysical Sciences Department at the University of Chicago. Primary goals of the immersion year include (1) gaining a scientific overview of key physical components of
IGMS: Coupling and Feedback in the Climate System
With this award we will purchase a modern gas source isotope ratio mass spectrometer with a high temperature elemental analyzer. The mass spectrometer will replace the aging Delta S that is currently operating and aging in the Stable Isotope La
Acquisition of a gas source isotope ratio mass spectrometer and high temperature elemental analyzer
has unique and innovative potential applications in fields such as understanding glacial processes in Antarctica, evaluating interactions involving climate, climate change and mountain building, to providing valuable new information on the for
Acquisition of microscope and automated stage system for fission-track analysis
The development of sustainable energy solutions that will meet the needs of a growing world population, while reducing greenhouse gas emissions, will rely in large part on renewable energy sources. With a global radiation flux of 174,000 TW, so
Phase Segregated Inorganic Heterostructures for Low Cost, High Efficiency Photovoltaics
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  While the number of women receiving advanced degrees in the geosciences has been rising, the face of scientific leaders in academia remains domin
ARRA Collaborative Research: Facilitating career advancement for women in the Geosciences through the Earth Science Women's Network (ESWN)
This Small Business Technology Transfer Phase I Project addresses the efficiency limitations of proton exchange membrane (PEM) electrolysis in order to provide a potentially renewable, cost-competitive hydrogen source for fueling and backup pow
STTR Phase I:  Development of High Temperature Membranes for Increased PEM Electrolysis Efficiency
The design on networked control systems for chemical processes and demonstrate their application and effectiveness in the context of process systems of industrial importances.
CPS: SMALL: DESIGN OF NETWORKED CONTROL SYSTEMS FOR CHEMICAL PROCESSES
This NSF award by Biosensing/CBET program supports work by Professor Vladimir V. Tsukruk from Georgia Institute of Technology on fundamental Raman scattering properties of nanoporous 3D membranes decorated with aggregates of noble metal nanostr
ARRA: NANOPOROUS 3D SUBSTRATES FOR LABEL-FREE TRACE RAMAN DETECTION OF BIOMOLECULES
Achieving solar-to-electric energy conversion using inexpensive, abundant and nontoxic materials is an important goal. While silicon is a material that fits most of these criteria, highest efficiency solar cells are made from expensive single c
Copper Zinc Tin Sulfide Based Solar Cells
To support the preservation of jobs threatened by declines in philanthropic and other support during economic downturn, as described in application A09-904071.
Arts & The American Recovery and Investment Act
Arts and the American Recovery&Reinvestment Act of 2009
Arts and the American Recovery & Reinvestment Act
Arts & the American Recovery & Reinvestment Act of 2009
To support the preservation of jobs that are threatened by declies in philanthropic and other support during the current economic downturn.
BUFFALO PHILHARMONIC ORCHESTRA SOCIETY, INC.
To support the preservation of jobs that are threatend by declines in philanthropic and other support during the current economic downturn, as described in our application and the approved project budget.
'Many of the future applications of systems and control that will pertain to cyber-physical systems are those related to problems of (possibly) distributed estimation and control of multiple agents (both sensors and actuators) over networks. E
CPS: Small: Random Matrix Recursions and Estimation and Control over Lossy Networks
Recent advances in enzymatic synthetic methods using biocatalysts have lead to environmentally friendly production methods of beta-lactam antibiotics. These methods have been limited in their industrial use due to the difficult separation of th
(ARRA) Liquid membranes in nanopores with strip dispersion for antibiotic recovery
To support the preservation of jobs that are threatened by decline in philanthropic and other support during the current economic downturn, as described in our application (A09-903244) and the approved project budget.
To support the preservation of jobs that were threatened by declines in philanthropic and other support during the economic downturn.
To support the preservation of jobs that are threatened by declines in philanthropic and other support during the current economic downturn, as described in our application (A09-905586) and the approved project budget.
Art and the American Recovery & Reinvestment Act of 2009
Juneau: Glacier Highway,  Amalga Harbor to Eagle River Kayak Launch, Reconstruction and Widening
There are currently over two million people in the United States suffering from various degrees of paralysis with an additional eleven thousand new cases of spinal cord injury each year. A means to rehabilitate these individuals would thus have
Neuroimaging of Motor Imagery for Brain Computer Interface Applications
'When Chuck Yeager broke the sound barrier with the first supersonic flight in 1947, the crucial technologies of the day that enabled such an endeavor were associated with aerodynamic design and strength of materials. During the last few decade
Multiscalar Measurements in Supersonic Flames
0933778 Fang  This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  Over the past decades, the searches for solid hydride materials for hydrogen storage focused on intermetallic compounds that store
LIGHT METAL SOLID SOLUTION ALLOYS FOR HYDROGEN STORAGE
Arts and the American Recovery @ Reinvestment Act of 2009
To support the preservation of jobs that are threatened by declines in philanthropic and other support during the current economic down turn, as described in our application (A09-906009) and the approved budget.
The Partnership in Research and Education in Materials (PREM) at the City College of New York (CCNY) involves a collaboration with the Materials Research Science and Engineering Center (MRSEC) at the University of Chicago. The PREM has two broa
COLLABORATIVE RESEARCH PREM:  CITY COLLEGE-CHICAGO MRSEC PARTNERSHIP ON THE DYNAMICS OF HETEROGENEOUS AND PARTICULATE MATERIALS
This engineering education research award to Tufts University in collaboration with University of Colorado-Boulder and Michigan Technological University will study how service learning activities can best be used to enhance student learning abo
Collaborative Proposal: Synergistic Integration of Sustainable Engineering Education and Project-based Service into Engineering Curriculum
The Urban Teaching Fellowship program for STEM professionals is supporting two cohorts of 10 NSF Teaching Fellows per year to participate in the Philadelphia Teacher Residency (PTR) program. Each Fellow is being supported for a total of five ye
Urban Teaching Fellowships for STEM Professionals
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).   This is a collaborative project involving a consortium of six premier U.S universities and one national laboratory to train graduate students in
Collaborative Research: Graduate Student Training Through Research on Plasma-Based Accelerators
The overall purpose of the Learning To Teach for Equity in Science and Mathematics Classrooms:  The Florida State University Noyce Scholarship Program (a program funded by the Robert Noyce Teacher Scholarship Program-Phase I Awards) is to attra
Learning To Teach for Equity in Science and Mathematics Classrooms: The Florida State University Noyce Scholarship Program
The Drexel University Noyce Scholarship Phase II program will continue to address the national need and the local need for high quality teachers in high needs schools. In partnership with the School District of Philadelphia, the program has pl
Drexel University Robert Noyce Scholarship Program – Phase II
The UTeach model is transforming the STEM teacher education program at the University. Features of intellectual merit include developing compact four-year degree programs that include both a content degree in mathematics, physics, biology or ch
CSUTeach: Preparing a New Generation of Noyce Scholars
To support the preservation of artistic programming jobs that are threatened by declines in philanthropic and other support during the current economic downturn.
To support the preservation of jobs that are threatened by declines in philanthropic and other support during the economic downturn, as described in the application and the approved project budget.
The K-State Robert Noyce Scholarship Program is increasing the supply of highly qualified middle and high school teachers (Grades 6-12) in biology, chemistry, earth and space science, and physics. The program is providing opportunities for 20 f
Math for America Los Angeles (MfA LA), a non-profit organization formed by the University of Southern California (USC), Claremont Graduate University (CGU) and Harvey Mudd College (HMC), seeks to raise student achievement in the greater Los Ang
Math For America Los Angeles: Improving Student Achievement By Focusing On Teacher Quality, Preparation and Professional Development
US93 11.07 MS to 5.60 MN of Elko Street in Contact, NV
This project seeks to develop and use a suite of freely-available internet chat-based tutorials for integrating computer modeling and design skills within any mechanical engineering undergraduate program. These tutorials will not only allow stu
Collaborative Research:  Agent-Monitored Tutorials to Enable On-Line Collaborative Learning in Computer-Aided Design and Analysis
TITLE:   'Student Training Through Research on Plasma-Based Accelerators.'   This project seeks to provide a coordinated learning and research experience for Ph.D. students from seven universities that have developed different experimental and
COLLABORATIVE RESEARCH: GRADUATE STUDENT TRAINING THROUGH RESEARCH ON PLASMA-BASED ACCELERATORS
The Division of Chemistry supports Susan Odom of the University of Illinois at Urbana-Champaign (UIUC) as an American Competitiveness in Chemistry Fellow. Dr. Odom will investigate the feasibility of encapsulating chemical species into lithium
Microencapsulated Molecular Regenerators for Lithium Ion Batteries
'This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).'  Intellectual merit  This nano related collaborative research program develops a new device integrating a microfluidic chip with a controlled en
Collaborative Research: Direct Exploration of New Nanoscale Structures using a Microfluidic Chip Integrated with Cryo-TEM
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  This study addresses several issues in modeling of fluid flow phenomena in systems with deformable fluid interfaces and structured solid surfaces
Interaction of fluid interfaces with structured solid surfaces
The United States faces an urgent and increasing need to educate and produce scientists and engineers. Within the context of a global marketplace of ideas and products, the competitiveness of our economy and the supporting innovation and develo
IRES Poland - Experience in Civil Infrastructure Systems
This project will research the thermal and thermoelectric properties of Graphene.
Measuring the thermal conductivity of graphene
The project will develop a new framework for mathematical modeling of rechargeable batteries, taking into account statistical thermodynamics, concentrated-solution reaction rates, elasticity, crystal anisotropy, stochastic effects, and composit
Experiments at the Tevatron and the Large Hadron Collider are poised to shed light on the nature of electroweak symmetry breaking. New experimental and theoretical tools are being used to probe the structure of matter at high temperature and hi
The purpose of this contract is to create a set of services to the Spoken Dialogue research community. DialRC is committed to furnishing data, running studies, providing educational material and organizing a Challenge for researchers around the
CI-ADDO-NEW: Dialog Research Center (DialRC)
for molecular structure and high-speed sequencing.  The infrastructure will help in training a new generation of graduate students. Students participate in a dual-degree program in which they do a PhD in physical sciences or engineering and a
II-NEW: A Dedicated Computing Platform For Large Spatiotemporal- Scale Atomistic Simulations of DNA Translocation and Self- Assembly
'This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). The partially completed IceCube neutrino observatory, located near the geographic South Pole, is already collecting physics data in the largest i
Search for Tau Neutrinos in IceCube Data
This Award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).    TECHNICAL SUMMARY:    This project seeks to develop a new mathematical framework for the description of crystal orientations, as well as misori
Quantifying Material Microstructures with Quaternions
Field theories provide our best known description of the fundamental interactions of Nature. In many situations, one can make significant progress by considering the theory. Perturbatively, starting from a collection of waves propagating indepe
RUI: Oscillons and Casimir Forces in Classical and Quantum Field Theory
In the 1920's quantum mechanics replaced the classic 'solar-system' model of the atom where electrons follow simple circular and elliptical paths around the nucleus. Quantum mechanics is a more powerful model than its predecessors in that it mo
RUI: An Experimental Investigation of the Influence of Background Gas Collisions on the Classical Orbits of Rydberg Electrons
The research here will center on two major themes, pursued with theoretical calculations, both numerical and analytic: (i) The first part of the work examines the time-dependence of quantum entanglement, to clarify and extend recently identifie
FEW LEVEL MODELS IN ATOMIC RADIATION THEORY
Many proteins in nature, such as silk and elastin, have superior physical properties. Inspired by the superior properties of these proteins, the goal of this project is to investigate an Evaporation-Assisted Plasma Lithography process for assem
Evaporation Assisted Plasma Lithography for Biomimetic Proteins
This project has several goals. First, together with M. Batanin and D.Tamarkin, the P.I. is going to prove the Deligne conjecture for Hochschild chains. Second, together with D. Tamarkin and B. Tsygan, the P.I. is going to prove the formality o
Higher algebraic structures, Deligne's conjectures and formality theorems
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  The principal investigator is interested in the study of the geometry of moduli spaces, especially those that are birational to modular varieties
Birational Geometry of Moduli Spaces and Applications
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). The International Arctic Buoy Program (IABP) is one of the oldest continuously-operating environmental monitoring networks in the high Arctic. Thi
Coordination, Data Management and Enhancement of the International Arctic Buoy Programme
This research project focuses on a new mechanical design, analysis and simulation framework for protein molecules. The fact that proteins are nano devices developed through evolution by nature suggests that the development of biomimetic artific
A Mechanics Framework for the Analysis and Design of Protein Based Nano Machines
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). It will provide continued support to perform operations and to analyze data from the VERITAS Observatory. It will also support the group's role in
GAMMA RAY ASTRONOMY AND ASTROPHYSICS WITH THE VERITAS OBSERVATORY
There exists no global database that defines the thermal state of permafrost within a specific time interval. Internationally, reported or unpublished temperature measurements have been obtained at various depths and periods over the past five
AON: Thermal State of Permafrost (TSP) in North America and Northern Eurasia: The U.S. Contribution to the International Network of Permafrost Observatories (INPO)
of asphalt overlay 22' wide will offer the most economical, safest road to the new facility.
This is a modification to an existing construction contract No. 08CC603730, awarded 9/9/2009, full and open competition.  This modification provides American Recovery and Reinvestment Act of 2009 (ARRA) funding for needed changes in the work to
Adams County Head Start 2009 ARRA COLA and Quality Improvement Funding. Adams County Head Start serves primarily low income children ages 3 to 5 providing comprehensive services addressing the educational and health needs of children, and offer
UPPER ARKANSAS AREA COUNCIL OF GOVERNMENTS
Increase teacher education moving teachers closer to obtaining degrees as requred by the Head Start Act.    Improve facilities to assure safe and healthy environments for pre-school children.    Create .5 FTE to lower case load of family manage
Head Start 2009 Arra COLA Quality Improvement Funding
RIO GRANDE CHILD DEVELOPMENT FAMILY SERVICES
ARRA Cost of Living Adjustment (COLA)in the amount of $9598., and Quality Improvement Funding of $29,100. consistent with the provisions of Section 640(a)(5) of the Head Start Act
ARRA Funding for Personnel, Fringe Benefits, and Training.
Head Start 2009 ARRA COLA Quality Improvement Funding For Head Start serving 270 center based children in Burke, Mountrail, Renville and Ward Counties of ND providing educational services to 3-5 year olds which also serves 85 Early Head Start c
OGDEN-WEBER COMMUNITY ACTION PARTNERSHIP, INC.
Ogden-Weber Community Action Partnership Head Start 2009 ARRA COLA & Quality Improvement Funding Head Start services were provided to 703 low income children and their families through out Weber county in Northern Utah. OWCAP Head Start offers
Head Start 2009 ARRA COLA & Quality Improvement
Central Montana Head Start has received ARRA monies to help supplement funding so CMHS is able to maintain and yet enhance its services to children and families.  The total amount received was $61,151 of which 1.84% ($15,043) was designated COL
COLA FUNDS:  7,592.00 The program will use the FY09 COLA funds to temporarily increase the portion of staff salaries paid for by Head Start funds per the requirements of Head Start grant.  The additional funds will help offset shortfalls in sal
The funds will be utilized to maintain and provide training to staff, improve quality in our classrooms, provide health services to our community and allow us to offer training to our families.
BERING STRAITS REGIONAL HOUSING AUTHORITY
Native American Housing Block Grant, Construction of 11 Homes. 4 homes in Elim, 4 homes in Koyuk and 3 homes in Golovin
Dillingham Housing Development and Regional Housing Renovations
Rental Unit Construction – From the selection submitted by RIM First People architectural firm, a floor plan was selected.  Using information available from current Tribal surveys, the TDHE Board selected the most appropriate floor plan and s
Native American Housing Block Grant, Formula-new construction, acquisition, rehabilitation including energy efficiency
Indian Housing Block Grant Formula Allocation
Native American Housing Block Grant American Recovery and Reinvestment Act
American Recovery and Reinvestment Act (Recovery Act) of 2009 - Native American Housing Block Grant Indian Housing Amendment
1937 Act Current Housing Stock Site Improvements
2008 Torres Martinez ARRA - Formula (New Construction)
IHB funds received were to replace roof,gutter, downspouts on existing housing stock; concrete repairs to walkways, build storage building and purchase shingles for housing program roofs.
Construction of two single family dwellings.
NAHASDA  Construction of two single family dwellings.
Assistant Secretary for Community Planning and Development
this grant will be spent to construct a single family home on the lower sioux reservation.
Native American Block Grant Formula:  New Construction, acquisition, rehabilitation, including energy efficiency, conservation and infrastructure development
American Recovery and Reinvestment Act of 2009 Indian Housing Plan Amendment.  Modernization ,Rehabilitation, Planning, and Administration of rental housing with an outcome of improved quality of substandard units and improved energy efficiency
Modernization and Acquisition of rental units with ARRA
WINNEBAGO HOUSING & DEVELOPMENT COMMISSION
Native American Housing Block Grant Formula, new construction, acquisition, rehabilitation, including enery efficency,windows, furnaces, insulation, water heaters and kitchen appliances
YERINGTON PAIUTE TRIBAL HOUSING AUTHORITY
Native American Housing Block Grant Formula - New Construction, Acquistion, Rehabiliation including Energy Efficiency and Conservation, and Infrastructure Development.  The award will be used for maintenance, rehabilitation, and energy efficien
Energy Efficiency Rehabilitation of 30 Rental Units of Current Assisted Stock and Drainage Improvement Rehabilitation of 3 Rental Units
Native American Housing Block Grant, Formula, New Construction.  The Sunrise Acres Expansion Project’s overall purpose and expected results of this award is to improve living conditions for the elderly and near elderly population of our servi
Senior Citizens Housing & Retirement Communities
The overall purpose for funds received by the Recover Act is to provide ten (10) single family homes for low income native american families.
American Recovery Act of 2009 for Indian Housing Block Grant
Rolling Meadows/Road & Utilities Project
GRAND RONDE TRIBAL HOUSING AUTHORITY, THE
Infrastructure: Rerouting sewer disposal pipe for two housing projects including 74 rental units.  3 six-room Adult Foster Care Homes, one Elder Activity Center, to fully supply sufficient waste for efficient operation of two Tribal Sewer Treat
Infrasturcture Development, housing rehabilitation and new housing development
PORT GAMBLE S'KLALLAM HOUSING AUTHORITY INC
Construct three bedroom single family homeownership units on scattered sites on the Spokane Indian Reservation.
Spokane Tribe of Indians, Spokane Indian Housing Authority, American Recovery & Reinvestment Act of 2009, FY 2008 Indian Housing Plan, Grant No. 08SH5314900
Native American Housing Block Grant, Formula - New construction, acquisition, rahbilitaiton including energy efficiency and conservation, and infrastructure development.
2008 ARRA Tallawhalt Rental Housing Land & Infrastructure Project.
FY 2009 Recovery Act Allocation to be used for new construction; acquisition;rehabilitation, including energy efficiency and conservation; and infrastructure development.
Native American Housing Block Grant. Formula.New Construction,aquisition, rehabilitation, including energy effiency and conservation and infrastructure develeopment.
To assist with building one new log cabin, and to assist tribal members with building materials to build their own log homes.
elder rehab purchase furnace and wood stoves for low income elders.
All IHBG funds provided under the Recovery Act must be used for new construction, acquisition, rehabilitation, including energy efficiency and conservation, and infrastructure development.
Assist 8 families with Rehabilitation activities
ARRA IHP Amendment Rehabilitation of Rental Housing
Elk Valley Rancheria Rehabilitation of Rental Housing
Rehabilitate and rennovate eligible Band member housing units on the reservation to enhance and improve energy efficiency.
ARRA funds for housing repairs assistance:  funding for housing inspection and to assist in repair
The Indian Housing Block Grant - ARRA provides funding for the improvement and betterment of the Native American communities including low- and moderate-income housing.
The ARRA funds are being used for energy efficiency rehabilitation work on current homes.
assist tribal members and other Indian people obtain housing
The Delaware Nation intends to modernize one mututal help unit of 1937 Act Housing and to convert one residential structure that was formerly used as a storage unit back into a residential structure.
Tonkawa Tribal Housing Rehabilitation Program
Native American Housing Block Grant, Formula- New Construction, acquisition, rehabilitation including energy efficiency  and conservation, and infrastructure development.
2008 ARRA Rental and Owner-occupied Housing Rehabilitation  Project
Native American Housing Block Grant, Formula - rehabilitation including energy efficiency, conservation and infrastructure development
Modernization of 1937 Act Low-Income Rental Units
Rehabilitation to existing Homeowners. Funding was awarded for the following activities: 1.Demolition, Installation and Set-up of manufactured home.
This project integrates research and education to advance the state of knowledge of the mechanism of frost-induced damage in Portland cement concrete under freeze-thaw cycles. The primary objective of this research project is to combine experti
Collaborative Research:  Understanding Mechanism of Internal Frost-Induced Damage of Concrete from Microstructure Aspects
This project is a collaboration between Drexel University and Merck Inc & Co and addresses the processing and optimization of multilayered tablets.  Multilayer tablets are becoming a key drug delivery method for coexisting medical conditions an
GOALI:  Processing and Optimization of Multilayered Pharmaceutical Tablets
The objective of this research is to develop nanomanufacturing methods for fabrication of shape-specific ?smart? nanoparticles capable of delivering drugs or imaging agents to targeted tissues in response to disease-specific or physiological si
High Throughput Nanoimprint Manufacturing of Shape-Specific, Stimuli-Responsive Polymeric Nanocarriers for Drug and Imaging Agent Delivery
This project involves a program of research in the intersections of ergodic theory and additive combinatorics. Most of the problems are within ergodic theory and are related to the analysis of the long-term behavior of systems whose dynamics ar
Fefferman has been working to find efficient algorithms to interpolate multidimensional data by an interpolating function that is 'nearly as smooth as possible' (under various interpretations of the phrase in quotes); and investigating a possib
Fourier analysis and partial differential equations
The bispectral problem appeared first in the pioneering work of Duistermaat and Grunbaum. It asks to classify spectral problems possessing a hidden symmetry between the space and the spectral variables. The goals of this proposal is to establis
ARRA: FROM BISPECTRALITY TO INTEGRABLE SYSTEMS, ORTHOGANOL POLYNOMIALS, HEAT EQUATIONS AND W-ALGEBRAS
The objective of this research is to demonstrate a new table top photolithography scheme capable to print sub-50 nm features. The approach is based on projection holographic lithography, consisting of printing photoresist with the reconstructed
Table Top EUV Holography:  A New Approach for Versatile Nanolithography
Electrical and Computer Engineering Department
The ARRA funding allowed the DSS to serve a population who are ineligible under regular CSBG funding.  The funds allowed for start-up costs for some new programs and expansion of existing programs.  The DSS, though the community action agencies
This is an investigation of the response of northern boreal forests to changes in arctic seasonality using an existing circumpolar network of centennial to millennial-length tree-ring width and density records that will be integrated with targe
Collaborative Research: Shifting Seasonality of Northern Forest Response to Arctic Environmental Change
Tundra soils are key regulators of many aspects of the Arctic System. Arctic soils have large stores of carbon (C) and may act as a significant CO2 source with warming. However, the key to understanding tundra soil processes is nitrogen (N), as
Collaborative Research: The Changing Seasonality of Tundra Nutrient Cycling: Implications for Ecosystem and Arctic System Functioning
International Environment, Population & Sustainability (Draft Code - DO NOT USE)
International, Foreign Affairs & National Security
It is well established that viruses play an important role in regulating the structure and function of marine ecosystems. However, we lack a mechanistic understanding of how bacteria cell receptors constrain virus infection, which has implicati
Collaborative Research: Characterizing the Constraints on Virus Infection of Cyanobacteria
Invasive species are increasingly introduced by human activities to new regions of the world where those species have never existed previously. In the absence of natural enemies (predators, competitors, and diseases) from their homeland, invasi
Ecological Release and Resistance at Sea: Invasion of Atlantic Coral Reefs by Pacific Lionfish
Intellectual Merit Nanoparticles catalyze many chemical transformations in organic synthesis, pollutant removal, and energy production; intense efforts are thus made to characterize the structure and understand the catalytic properties of nanop
SINGLE MOLECULE INVESTIGATION OF NANOCATALYSIS
and the publication of the first Handbook of Experimental Political Science that will contain the papers from the conference. The conference and volume include contributions from more than twenty-five leading political scientists. The basic go
This grant establishes a Census Bureau Research Data Center (RDC) at the University of Minnesota. The goals of the Minnesota RDC are twofold. First, the RDC will help Minnesota researchers, working in collaboration with the Census Bureau and th
The award supports an REU/RET which will provide 12 undergraduate physics majors from across the country with a ten week long genuine research project emphasizing one-to-one mentoring with faculty from a wide range of disciplines within the Pur
REU Site: Multidisciplinary Physics at Purdue University
This engineering education research award to Kansas State University will employ researchers to integrate the concepts of alternative energy and sustainability into the electrical and computer engineering (ECE) curriculum. These concepts will b
REU Site: Ecology, Evolution, and Genomics of Grassland Organisms
Two groups of migrants - aging baby boomers and Latino immigrants - are  converging on rural America, and combined these groups will  significantly transform their destination communities in the coming  decades. While these migration streams ha
Collaborative Research: Linked Migration and Changing Labor Markets in the Rural United States
The newly discovered process of anaerobic ammonium oxidation (anammox) is an important process in marine environments. The contribution of anammox to global N budgets remains highly uncertain, however. To develop a predictive understanding of n
One of the greatest physicists Vladimir Gamow compared our universe with a giant reactor or cauldron, in which all elements are cooked up via nuclear reactions. The process itself is called 'nucleosynthesis.' We are all made of the products of
NEW THEORETICAL APPROACHES IN NUCLEAR REACTIONS AND APPLICATIONS FOR NUCLEAR ASTROPHYSICS
The main objective of this project is to develop stable, high-purity, SWNT-dispersions based on large-scale processes that minimize risks to the environment and human health
Rational Design of High-Purity Carbon Nanotube Dispersions Through Acute and Full Life-Cycle Toxicity Studies
The cost of downstream processing is a major component of production of protein biopharmaceuticals. Affinity chromatography, wherein an immobilized ligand is used to selectively separate the desired target protein from a complex mixture, can gr
Hyperthermophilic Affinity Ligands For Protein Purification
The Athapascan or, as speakers prefer, Dene languages constitute the largest and most geographically widespread language family of native North America. Five separate sub-groupings have been identified: Alaskan, Northern Interior (BC/Yukon), Ma
AN INTERACTIVE SPEECH ATLAS OF DENE SPEAKING COMMUNITIES IN THE MACKENZIE BASIN (693-3)
Professor Kurtis Paterson of Michigan Tech University will lead twelve engineering graduate students from Michigan Tech in an International Research Experiences for Students project, with twelve engineering students from the University of Dar e
IRES US-Tanzania: Developing Global Engineers and Scientists through Collaborative Technology Innovation for Public Health Improvements in Tanzania
Nature displays a prodigious diversity of propulsion mechanisms in fluid systems. We have discovered a remarkable new one that operates in density-stratified environments. The underlying mechanism is a little-studied phenomenon, diffusion-drive
This International Research Experiences for Students (IRES) project, funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5), invites students to participate in a research, education and conservation program that inco
US-Chile IRES: Integrating Ecological Sciences and Environmental Ethics for Biocultural Conservation in the Temperate Sub-Antarctic Region of Southwestern South America
Many concentrated materials consist of soft particles (e.g., emulsions, elastic particles, microgels, star polymers or polymer-coated particles) packed and deformed into an amorphous state. These pastes are important as rheological modifiers fo
Flow, Memory and Aging of Soft Particle Pastes
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).0854399/0854445Mankoff/LandayThis research will leverage mobile technologies and sensors to empower individuals with personal feedback about their
Collaborative Research:  Mobilizing Information Technology Systems to Motivate Reduced Energy Consuption and Carbon Dioxide Emissions
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).     Intellectual Merit: This project proposes to test the hypothesis that natural tracers measured at temporal resolution similar to water fluxes
Collaborative Research: High Resolution Sensor Networks for Quantifying and Predicting Surface-Groundwater Mixing and Nutrient Delivery in the Santa Fe River, Florida
The proposed research will explore expanded use of a commonly implemented remote sensing tool, hyperspectral imaging (HSI), within the realm of eutrophication and aquatic ecosystem metabolism. HSI has been successfully a remote sensing tool for
Waters Network: Observing and Predicitin Freshwater Eutrophication-Algal Bloom Dynamics Using Local Hyperspectral Imaging
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). The research objective of this award is to develop algorithms and experimental demonstrations for partially automated cooperative active safety sy
GOALI: Hybrid Dynamic Feedback for Partially Autonomous Cooperative Active Safety Systems
FRG: Collaborative Research: Generalized Geometries in String Theory
The award will fund the support of Prof. Yuri Gershtein research program on CMS Experiment at CERN and outreach efforts with QuarkNet. The ultimate goals of the CMS experiment is the discovery of Higgs boson and investigation of its properties,
Research in Experimental High Energy Physics (PHY Elementary Particle Accel User)
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  The proposed work is focused on gestural human computer interfaces, camera-based interfaces for individuals with severe physical disabilities, co
II-EN: Infrastructure for Gesture Interface Research Outside the Lab
In recent years, graphics processing units( GPUs)have emerged as a powerful alternative to CPU based computing, especially for scientific computing. However, GPUs follow the stream programming model. It is completely different from traditional
CRI II-New: Data-Parallel Platform for Large-Scale Simulation of Agent-Based Models in Systems Biology
The work constitutes a significant update of WordNet, a large electronic lexical database of English that is a cornerstone of research and applications in computational linguistics, Natural Language Processing, Knowledge Representation, Semanti
CI-ADDO-EN: A Second-Generation Architecture for WordNet
This project is focused on investigations of the fundamental constants, elementary interactions and basic symmetries of the Standard Model. The proposed research is based on precision experiments with low-energy muon beams and includes continui
Studies of fundamental constants, interactions and symmetries via low-energy, high-precision muon experiments
Collaborative Research: Decision-Dependent Stochastic Processes Inference and Optimization
The overall purpose and expected outcomes of the project are described as follows.  The project investigates a novel wireless signal network that can function as a versatile sensor to characterize properties of subsurface geo-media and to monit
Wireless Signal Networks for Subsurface Modeling and Geo-Event Characterization
This award is funded under the American Recovery and Reinvestment Act of 2009(Public Law 111-5).Recent measurements of the Bering Strait throughflow fluxes find strong seasonal and interannual variability, so far unpredictable ? the heat flux i
Funds are provided to deploy a single, strategically placed mooring in the core of the western Arctic boundary current east of Barrow Canyon, which will collect measurements permitting estimation of both the alongstream and cross-stream fluxes
Collaborative Research: An interdisciplinary monitoring mooring in the western Arctic boundary current: Climatic forcing and ecosystem response
Ozone plays a critical role in global and regional atmospheric chemistry and has a significant impact on global climate, making it vital to understand ozone source and sink processes. Although substantial progress has been made, there are many
Using Oxygen Isotopes to Constrain Ozone Sources and Sinks
The construction of any infrastructure on or within the ground will subject the surrounding soils to complex loading modes. In order to understand the short and long term behavior of an infrastructure element such as a building or a tunnel it i
Towards an Integrated Computational-Experimental Laboratory Testing Framework for Soil Behavior Characterization and Modeling
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  The objective of this project is to develop and apply a novel technology for the automatic detection and real-time mitigation of accidental or de
Detection and Mitigation of Hazardous Releases in Infrastructure Systems
This project aims to explore a new approach of civil structure health monitoring by making the concrete pavement itself as an installed detector. The electrical network of carbon nanotubes (CNTs) can be utilized to detect concrete cracking; the
The mission of the National Earthquake Information Center (NEIC) is to determine rapidly the location and size of all destructive earthquakes worldwide and to immediately disseminate this information to concerned national and international agen
Provide Hydrological Instrumentation: High Data Rate (HDR) GOES Data Collection Platforms (DCP) with loggers and radios; Submersible Pressure Sensors; Non-submersible Pressure Sensors; Combination Non-Submersible Pressure Sensors, Gas Systems,
Storm Shelters & Trailer House Lottery Draw
Head Start 2009 ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistant with the provisions of Section 640(a)(5) of the Head Start Act. This award provides for ARRA Cost of Living Adjustment (COLA) and Quality Improvem
DISTRICT IV HUMAN RESOURCE DEVELOPMENT COUNCIL (INC)
HEAD START 2009 ARRA COLA QUALITY IMPROVEMENT FUNDS:  To recruit and retain qualified educational staff, impromvements to learning environment in classrooms and playgrounds.  Repairing parking lot to improve the acesability and safety for clien
DISTRICT IV HUMAN RESOURCES DEVELOPMENT COUNCIL NORTHERN MONTANA HEAD START
reauthorizing the Head Start program. P.L. 110-134 changed requirements for education staff
Head Start 2009 ARRA/Quality Improvement Funding
The ARRA COLA will be used for salary increases and increased cost of fringe benefits.  The ARRA Quality will increase the current Family Services Workers (FSW) time worked from forty one (41) weeks to fifty two (52) weeks and adding one (1) ne
This award provides for ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistant with the provisions of Section 640(a)(5)of the Head Start Act for the Head Start program.  Head Start promotes the school readiness of low
Head Start 2009 ARRA COLA Quality improvemnent
Head Start staff COLA increases to compensation and benefits for grant period, Quality Improvement for staff's professional development, and Quality Improvement to H/S programs physical environments
Mayville State University requested ARRA funding in accordance with PI-HS-09-06 to provide salary and fringe benefit increases to all program staff. Recent wage comparability studies indicated teaching staff were on the lower end of the scale.
TECHNOLOGY FOR THE RURAL ENHANCEMENT OF COMMUNITIES
This award provides for the Head Start 2009 ARRA Cost of Living Adjustment (COLA) and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start and Early Head Start programs.  Head
The COLA and Quality project for First Steps Early Head Start provided funding for quality improvements, staff training and cost of living increases to a year-round home and center-based comprehensive early childhood development program, servin
Fremont County Family Center, 1401 Oak Creek Grade Road
Adams County Head Start has been awarded Expansion funding for an additional 75 children by the Head Start Region VII Office. Expansion funds are being used for: (1) Partnering with three different sites to provide Head Start quality education
This award provides ARRA Head Start Expansion funds to serve an additional thirty-two (32) children in two (2) center-based classrooms during the school year in Cascade County.
EASTERN SHAWNEE TRIBAL HOUSING AUTHORITY
Native American Housing Block Grant, Formula. New construction, acquisition, rehabilitation including energy efficiency and conservation, and infrastructure development.
All Recovery Act funds will be used for new construction, rehabilitation including energy efficiency conservation and infrastructure development. The funds will be expended to develop forty new public rental units at two site locations to house
Development and Modernization for new and existing NHA units
Native American Housing Block Grant, Formula - Rehabilitate and modernize 49 vacant and abandoned units under the current assisted 1937 housing stock throughout the Tohono O'odham Nation.  The 49 units will be modernized and rehabilitated to br
HOUSING AUTHORITY OF THE SAC AND FOX NATION OF MISSOURI
Modernzation of 40 homes. Roofing on 20 duplexes and window replacement on 20 homes.
The Houlton Band of Maliseet Tribal Housing Authority is planning on using funding to rehabilitate one roof on our current assisted stock, build a new 5,600 sq ft six unit apartment building inconjuction with a USDA 515 loan, develop a Low Inco
Housing Construction, Rehab of CAS, Planning and Admin
$114,386.00 was contributed to the construction of 2 duplexes that consisted of 2 bedrooms and one and a half baths each . One unit is completely handicap assessable, all 4 units have metal roofs, 95% efficient duel & off peek furnaces, energy
Modernization of 25 units, Energy Conservation equipment for 25 units, Electrical system upgrade on 35 units, site improvements, Planning and Administration for monitoring and completion of the project.
Santee Sioux Tribal Housing Authority IHBG ARRA Amendment 2009
Rehabilitation Assistance to Existing Homeowners
The PdCHA will modernize 10 1937 Act rental units in its current assisted stock to bring these units into compliance with decent safe and sanitary standards which will extend the useful life of the units, improve the quality of the units, impro
Modernization of ten 1937 Act rental units
American Recovery and Reinvestment Act (Recovery Act)of 2009
SANTO DOMINGO TRIBAL HOUSING AUTHORITIES
Water and Sewer Extention at Cedar Tree Subdivision Construct eight rental units
The Cheyenne-Arapaho Housing Authority was awarded under the recovery act $1,019,412.00 formula Indian Housing Block Grant.  The Housing Authority will purchase seven homes for low-income applicants with rehabilitation to them as needed.  The H
HOUSING AUTHORITY OF THE PEORIA TRIBE OF INDIANS OF OKLAHOMA
Native American Housing Block Grant - Formula PHA
Green Low Rent Development - infrastructure
UMATILLA RESERVATION HOUSING AUTHORITY LIMITED
Native American Indian Housing Block Grant, Formula-New Construction, acquisition, rehabilitation including energy efficiency and conservation, and infrastructure development. This grant is being utilized to Rehabilitate 21 of 50 homes that hav
Rehab/Construction renovations to existing stock (rental units) to include new heating and Air System, Re-Roofing, install energy sufficient doors and Staff 2 Temporary full time tribal members.
Native American Housing Block Grant, Formula-New Construction, acquisition, rehabilition including energy efficiency and conservation, and infrastructure development.
NEW CONSTRUCTION,ACQUISITION,REHABILITATION INCLUDING ENERGY EFFICIENCY AND CONSERVATION,AND INFRASTRUCTURE DEVELOPMENT.
Indian Housing Plan/Amendment/Indian Housing Block Grant 2008 Formula.
The Chippewa Housing Authority plans to replace the current furnaces in 155 of our 1937 Act units and replace them with 95% energy efficient furnaces.  We will also install approximatley 55 tank-less water heaters in the 1937 Act units.  We wil
Native American housing Block Grant formula funds for new housing Construction
Native American Housing Block Grant, Forumla - New Construction, acquisition, rehabilitation including energy efficiency and conservation, and infrastructure development.
Native American Block Grant, Rehabilitation
HUD Native American Housing Block Grant, Formula -  Infrastructure development.for a new 65-unit subdivision.
Modernization, Rehab, Planning & Administration
PENOBSCOT INDIAN NATION RECREATION COMMITTEE
1.  Provide rehabilitation to 14 homes; 2.  Construct 6 homes; and 3.  Design & construct Community Center.
NPHB Formula  New Construction Fema Units
1) Renovation of Day Care facilities to take it from a 2 star facility to at least a 4 star facility out of a possible 5 star system. 2)  Four homes will be renovated to facilitate elderly individuals and reduce their monthly operating expenses
1) Rehabilitation of a Day Care, 2) Rehabilitation of four Houses, 3)  Repair of Multi-Purpose building floor, 4) Rehabilitation of one office building, 5) Replace roofs on 13 apartment buildings.
Funding is provided to explore the variability in temperature and precipitation and their inter-relationship through Bayesian analysis of a combination of instrumental and proxy records. The premise of the research is that, climatologically, va
P2C2: A Bayesian approach to estimating temperature and precipitation and their inter-relationship over the last millennium
Collaborative Research: Reconstructing millennial-scale trends and variability in western Pacific convection and hydrology from large lakes on Sulawesi, central Indonesia
This grant produces paleoclimate datasets recording the timing, duration, frequency and magnitude of aridity cycles on a network of paired open and closed micritic basins along the western cordillera of North America from the Pacific NW to the
Collaborative Research; Spatial and Temporal Patters of Drought in Western North America during the Holocene
This award is a 2-year collaborative project between the University of New Mexico, Northern Arizona University and the University of Minnesota, Duluth to conduct detailed paleoclimatic analysis of an 82-m long lacustrine sediment core (VC-3) fr
Collaborative Research: A high-resolution middle Pleistocene paleoclimate record from the Valles Caldera, New Mexico
The objective of this research is to develop solutions that ensure reliable power delivery in high-performance multicore systems. Technology trends for multicore chips show increased on-chip noise sources, decreasing supply voltage levels, and
An Integrated Design and CAD Approach for Efficient Power Delivery in Multicore Processors
This project supported graduate student Yonggang Hu to get his Ph.D.  His work demonstrated that the polarization of electromagnetic ion cyclotron waves varies along magnetospheric magnetic field lines, that the relative amount of reflection or
Grad Student Support for Dipole Coordinate Hybrid Code Simulation
Climate sensitivity is generally studied using two different types of modules. Atmosphere-ocean general circulation models (AOGCMs, or coupled GCMs) include interactive ocean dynamics and detailed heat uptake, but they are computationally expen
Comparison of Climate Feedbacks in Atmospheric versus Coupled General Circulation Models
ARRA Collaborative Research: Program for Research on Oxidants: Photochemistry Emissions and Transport (PROPHET) 2009--Community Atmosphere-Biosphere INteractions EXperiment (CABINEX)
The PI's proposed research is concerned with the study of canonical Kahler metrics on algebraic varieties. There are deep conjectures relating the existence of extremal metrics to stability of the underlying algebraic variety and understanding
NORTHERN KENTUCKY UNIVERSITY RESEARCH FOUNDATION, INC.
The purpose of this award is to develop and assemble molecular building blocks for supramolecular structures that exhibit charge transfer when irradiated with light. The PI will design and synthesize linkers to assemble fullerenes, conjugated p
New Supra molecular Moieties for Organometallic for Supramolecular Photophysics
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). Force-feedback, or haptic, applications in medicine, engineering, and design are increasing in popularity and importance based on the advantages o
HCC: MEDIUM: COLLABORATIVE RESEARCH: HAND-MOUNTED TACTILE DISPLAYS FOR HAPTICALLY INDENTIFYING SHAPE & DEXTEROUS MANIPULATION
This research will address critical issues through a collective research effort to develop new algorithms and high-performance software development for data analysis. With the deployment of petascale computing systems, these problems can for th
ARRA: COLLABORATIVE RESEARCH: UNDERSTANDING WHOLE-GENOME EVOLUTION THROUGH PETASCALE SIMULATION
NSF/NCAR C-130 Modernization:To ensure that the NSF/NCAR C-130 remains a premier research platform, able to operate safely for the next 20 years, very important modernization efforts are planned:  1) Replace avionics to be compatible with the n
Probabilistic graphical models provide a powerful mechanism for representing and reasoning with uncertain information. These methods have been successfully applied in diverse domains such as bioinformatics, social networks, sensor networks, rob
III: Medium: Collaborative Research: Integration, Prediction, and Generation of Mixed Mode Information using Graphical Models, with Applications to Protein-Protein Interactions
This project determines the fundamental limits of network secrecy from a network coding perspective, and then applies this theory to improve security guarantees in peer-to-peer and wireless networks. As network coding gains prominence as an imp
'This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).'This proposal will address the provenance of computational processes and the data they manipulate. These are of fundamental importance in maintai
III:MEDIUM: PROVENANCE ANALYTICS: EXPLORING COMPUTATIONAL TASKS AND THEIR HISTORY
As both corporate and consumer-oriented applications introduce new functionality and increased levels of customization and delegation, they inevitably give rise to more complex security and privacy policies. Yet, studies have repeatedly shown t
TC: medium: User-Controllable Policy Learning
Wireless mesh networks promise a flexible and cost-effective solution for bringing high-bandwidth low-latency applications to the  home. Two orthogonal but immensely attractive approaches for designing high-performance mesh networks are network
(ARRA) NeTS-Medium: Collaborative research: Unifying network coding and cross-layer optimization for wireless mesh networks: From theory to distributed algorithms to implementation
Though perhaps unfortunate, as a practical matter software is often built with functionality as a primary goal, and security features are only added later, often after vulnerabilities have been identified. To reduce the cost and increase assura
TC: Medium: Collaborative Research: Techniques to Retrofit Legacy Code with Security
The theme of this project is to generalize the methods of global Riemannian geometry to better understand metric measure spaces, which occur naturally as singularity models for the Ricci flow. This proposal builds on joint work by the PI and Pe
GEOMETRY OF SMOOTH METRIC MEASURE SPACES AND RICCI FLOW
The host institution for this research is Harvard University under the sponsorship of Dr. Scott Edwards.  Variation in the arrangement of the building blocks of DNA define the structure of the genome, and this structure can have a profound inf
Postdoctoral Research Fellowships in Biology for FY 2009
The proposal is aimed at increasing understanding of the structure of the moduli spaces of stable holomorphic maps by combining ideas from several different fields of research. The core of the project seeks to use geometric and analytical metho
Moduli Spaces Relative Singular Divisors and Lagrangians
This project explores problems connected to large scale properties of random matrices and interacting particle systems. The beta-ensemble is a one parameter family of distributions of random points on a line; for specific parameter values it de
ARRA Random Matrices and Interacting Particle Systems
The general theme of this proposal is to find properties of the most symmetric spaces and dynamical systems that uniquely characterize these spaces. The PI proposes projects related to this goal with an emphasis on the following: a) understandi
EXTREMALITY OF SYMMETRY IN NONPOSITIVE CURVATURE, GEODESICS, AND THE DYNAMICS OF LARGE GROUP ACTIONS
The project supports the design and development of a sensitive, broadband antenna and receiver to observe the evolution with redshift of highly redshifted neutral hydrogen, throughout the epoch of reionization. The system, operating in the 45 -
EDGES: An Ultra-Clean Spectrometer for Fundamental Measurements of Cosmological Reionization and the Dark Ages
In recent years, the availability of high-throughput data from genomic, finance, environmental, marketing (among other) applications has created an urgent need for methodology and tools for analyzing high-dimensional data. The explosion of data
Exploring and detecting complex multivariate dependencies through sparse graphical models
'Vortices and Bubbles in Cryogenic Liquids' Superfluid helium at very low temperatures is known to flow without friction, but it is known that this superfluid state can be destroyed when the temperature of the liquid is raised above a critical
VORTICES AND BUBBLES IN CRYOGENIC LIQUIDS
The goal of this research program is to develop rational synthetic methods for the low temperature, solution phase synthesis of functional inorganic nanocrystals for energy applications. Lower temperature reactions are energy efficient and offe
New Low-Temperature Synthetic Routes to Functional Perovskite and semiconductor Nanocrystals
The investigator studies nonparametric methods for continuous-time jump processes that are contaminated by a background noise, or are affected by random clocks. In financial markets, for instance, the background noise is a byproduct of the way
Nonparametric Methods for Jump Processes Under Microstructure Noise
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).    NON-TECHNICAL DESCRIPTION:   The methods for production of most ceramic materials depend on a small amount of chemical additions that distribut
Collaborative Research: Development of an Additive Selection Criteria based on Interface Complexions
Nanoparticle self-assembly offers special opportunities for the design of next-generation materials. This project focuses on a new class of ultra-thin sheets, fabricated from single layers of metal nanoparticles. In this ultrathin limit, the sh
INVESTIGATION OF FREESTANDING NANOPARTICLE SHEETS
The two-dimensional electron gas confined to semiconductor interfaces has been one of the important model systems of contemporary condensed matter physics. When the level of disorder in the host semiconductor is low enough and the randomizing e
Termodynamic Measurements of Collective Phases of Two-Dimensionally Confined Charge Carriers
TECHNICAL SUMMARY:  This award supports theoretical research and education focused mainly on the light elements, including hydrogen under conditions of high pressure and high temperature. The PI aims to elucidate quantum orderings, both in hydr
SUPERCONDUCTIVITY AND OTHER QUANTUM ORDERINGS IN THE LIGHTER ELEMENTS
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS
This study provides statistical tools to explore three dimensional (3D) chromosome structures and directly addresses the important biological question that how the 3D structures facilitate the coordination in gene transcription.  Besides scient
Collaborative Research: Bayesian Hierarchical Methods for Modeling Chromosomal Spatial Correlation - ARRA Stimulus Funding
NON-TECHNICAL DESCRIPTION: Solid oxide fuel cells (SOFCs) offer an important new option for converting fuels to electricity with increased efficiency, reduced pollution, and reduced greenhouse gas emissions. The race to reap the commercial and
Collaborative Research: Three-dimensional Microstructural and Chemical Mapping of Solid Oxide Fuel Cell Electrodes: Processing, Structure, Stability, and Electrochemistry
The project is devoted to development and implementation of new algorithms for the modeling and computational investigation of deformation and breakup of interfaces that separate two immiscible liquids. The majority of the effort is focused on
Computational study of drop deformation in systems with two immiscible liquids
The PI and the team will use computer simulations to follow the formation of galaxies through the period 1-2 billion years after the Big Bang, when the cosmic gas was reionized by ultraviolet light from newly-formed stars and the active nuclei
This research project is an analytical and numerical study of the behavior of solutions to classes of partial differential equations that arise in optics, fluid dynamics, population dynamics, molecular dynamics, and thermodynamics. The problem
Selected Problems in Applied Mathematics
This award supports theoretical research and education with a focus to develop the principles that govern phenomena that emerge in networks with immediate application to biological systems and materials. The notion of a network is an abstract c
PI will continue his work to determine the masses of the different components of disk galaxies, in particular the stellar disk, the gaseous disk and the dark halo. He will assemble velocity-resolved maps in the H-alpha line of ionized gas and i
Primordial Dark Matter Halos and the Present Mass Distribution of Galaxies
The project is a three year survey of nearby stars to find faint companions of these stars and to analyze their spectra to study the chemistry and atmospheric structure.  Ultimately, we aim to image planets orbiting nearby stars.  Deliverables
Collarborative Research: Project 1640: Hyperspectral Imaging Survey of Nearby Stellar Environments
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).   Humans are increasingly living in urban ecosystems. Cities cover only one to two percent of Earth's surface, but they are important hotspots of
Collaborative Research: Coupling Human Choice and Biogeochemical Cycling in Urban Ecosystems
Spin coherence and spin transport are two of the core issues facing semiconductor spintronics and quantum information science today.  The central aim of this project is to examine in detail the electronic spin transport and spin coherence in a
Materials World Network: Investigation of Coherent Spin Transport in the Persistent Photoconductor AlGaAs Using All-Electronic Spin Injection and Detection
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  Dr. Townsend will undertake an exploration of the incidence, characteristics and evolutionary impact of wave transport by oscillation modes in ma
ARRA Wave Transport of Angular Momentum: A New Spin on Massive-Star Evolution
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). The goal of this proposal is to explore the microbiology of frost flowers -- delicate ice crystal structures with high brine content that form on
Frost flowers in Arctic winter: Sea-to-air transport of microbes and viruses
Damped and Sub-damped Lyman-alpha Absorbers: What Are They, and What Do They Tell Us About Galaxy Evolution? PROJECT SUMMARY The evolution of galaxies and the production of chemical elements in the universe are fun- damental issues in astrophys
Damped and Sub-damped Lyman-alpha Absorbers: What Are They, and What Do They Tell Us About Galaxy Evolution?
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  Dr. Madau and his team will combine observations of the gas from which the galaxies were formed with theoretical and numerical studies of the sta
The Imprint of Galaxy Formation on the Intergalactic Medium: from First Light to the Local Group
Dr. Robert L. Mutel of the University of Iowa and his students will undertake a research program to image the radio coronae of several active late-type binary stars at multiple epochs with unprecedented sensitivity, angular resolution, and posi
High Sensitivity Array Studies of Stellar Radio Coronae
Two major surveys of Galactic field halo stars will be carried out in order to illuminate and constrain models of early chemical evolution in the Milky Way Galaxy. In one, a detailed study of high resolution spectra of over 100 stars with known
The Chemical Compositions of Galactic Halo Field and Cluster Stars
Humans are increasingly living in urban ecosystems. Cities cover only 1 - 2% of Earth's surface, but they are important hotspots of biogeochemical cycling because they concentrate the consumption of food & energy that are produced beyond their
Dr. Moran will undertake a survey of the optical spectra of galaxies closer than about 250 million light years, making a census of their nuclear activity, which is powered by a central black hole. He will select galaxies from both the Sloan Dig
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).   Dr. Woosley will continue his extensive research on the origin of the elements and the end points of stellar evolution. This includes the evolut
Massive Stellar Evolution, Supernovae, and Nucleosynthesis
This project addresses the frontier problems of plasma dissipation and radiation in accretion flows onto black holes, when the density is so low that Coulomb coupling is inadequate to heat the electrons. Using magnetohydrodynamic turbulence gen
Dissipation and Radiation of MRI-Driven Accretion Flows around Low Luminosity Black Holes
Dr Wilson will study ten clusters of galaxies at redshift 0.87 < z < 1.34, which are seen as they were when the cosmos had expanded to only about half its present size. The clusters are chosen from a survey that combined 3.6-micron images from
The investigators will measure mercury (Hg) concentrations, mercury isotopes, and a suite of trace metals in previously-collected Arctic sediment cores in order to increase understanding of paleoceanographic conditions in the Arctic Ocean as we
Arctic Ocean redox history and Hg cycling using redox-sensitive trace metals and Hg isotopes: the influence of sea ice
This multidisciplinary proposal aims to improve understanding of ocean/glacier-ice interactions by linking oceanographic, glacier, and atmospheric measurements in a fjord/glacier system showing recent change to quantify processes occurring at t
Collaborative Research: Quantifying Glacier-Fjord-Ocean Interactions and Their Impact on Changing Ice Discharge: Kangia Nunata Sermia and Other Outlets, West Greenland
People across the globe are increasingly facing rapid changes in the resources on which they depend for food and survival. In the Arctic, climate warming is one of several interrelated forces of change that could threaten the livelihoods of ind
Modeling harvesting behavior to understand adaptation, mitigation, and transformation in northern subsistence systems
Understanding the role of environmental change of the long-term population dynamics of one surviving and two extinct arctic mammals.
COLLABORATIVE RESEARCH: UNDERSTANDING THE ROLE OF ENVIRONMENTAL CHANGE ON THE LONG-TERM POPULATION DYNAMICS OF ONE SURVIVING AND TWO EXTINCT ARCTIC MA
RUI: Synthesis and Evaluation of Group-1 Specific Neuraminidase Inhibitors
Prairie pothole lakes (PPL) are important hydrologic features in the glacial till of the Upper Midwest. A number of these lakes have developed unique water chemistries, including extremely high (10?s to 100?s of millimolar) levels of sulfate.
Collaborative Proposal: Redox Processes in the Sedimentary Porewaters of Prairie Pothole Lakes: Implications for the Attenuation of Pesticides
Moore's law promises consistent increasing transistor densities for the foreseeable future. However, device scaling no longer delivers the energy gains that drove the semiconductor growth of the past several decades. This has created a design p
CSR:Large:Collaborative Research:Reclaiming Moore's Law through Ultra Energy Efficient Computing
Moore?s law promises consistent increasing transistor densities for the foreseeable future. However, device scaling no longer delivers the energy gains that drove the semiconductor growth of the past several decades. This has created a design p
'This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).'  The ability to reason about the complexity of living organisms in diverse environments is one of the hallmarks of intelligence. In this project
HCC: Large: Intelligent Tracking Systems that Reason about Group Behavior
The Puna Plateau, northwestern Argentina, together with the Altiplano of Bolivia, is the second largest plateau on Earth. One popular model often invoked to explain the present day crustal structure and elevation of the Central Andean Plateau,
Collaborative Research: In Pursuit of Missing Andean Lithosphere: Constraining Late Cenozoic Crust-mantle Processes in the Puna Plateau, Central Andes
This research group will give one of the first detailed accounts of the sedimentary basin response to oceanic spreading-ridge subduction. Forearc basins, one of the most common along convergent margins, are large sediment repositories that have
Collaborative Research: Sedimentary Basin Response to Paleocene-Eocene Spreading Ridge Subduction in South-Central Alaska
The boundary between Earth's rocky mantle and metallic core is home to a patchwork collection of partially molten structures. These structures, characterized by sharp peaks and valleys, are relatively thin (10s of km in thickness), dense (up to
Collaborative Research: Structure and Dynamics of the Ultralow-Velocity Zone at the Core-Mantle Boundary
The proposed research is designed to fill critical gaps in our knowledge concerning the magmatic partitioning of selected elements among sulfides, Fe-(Cu)-S-O melts, and selected oxides and silicates. These elements fall into two important grou
This award in the Inorganic, Bioinorganic and Organometallic Chemistry program supports fundamental studies on multifunctional spin crossover materials.  Spin crossover compounds can exist in two magnetic states, transitions between which are a
Hybrid Fe(II) Spin Crossover Materials: Organic Conductors, Small Molecule Sensors, and Functionalized Nanoparticles
Intellectual Merit: Amorphous silicate spectral features have been observed in our solar system, young stellar objects, star formation regions, novae, diffuse and dense interstellar medium, and in extragalactic quasars and AGN. Dust contributes
EXTENDING THE LAU IMAGING EXPERIMENT TO STUDY THE DEEP TONGA SEISMIC ZONE
The Analytical and Surface Chemistry (ASC) program of the Division of Chemistry supports the research program of Professor Yves Chabal of the University of Texas at Dallas. Prof. Chabal and his students will examine the surface chemistry and ch
Surface Chemical Functionalization of Semiconductors and Nanostructures
This proposal seeks funding to study the evolution of the lithospheric mantle beneath the central Rio Grande Rift and Colorado Plateau margin. The project will provide insights into a variety of questions related to the tectonic and volcanic ev
GEOCHEMICAL INVESTIGATION OF XENOLITHS FROM THE CENTRAL RIO GRANDE RIFT AND COLORADO PLATEAU: CONSTRAINTS ON LITHOSPHERE EVOLUTION AND POSSIBLE DELAMINATION
This proposal details a series of experiments that seek to improve our understanding of ductile deformation in Earth's upper mantle.  It is evident from studies of naturally deformed peridotites that deformation microstructures such as lattice-
DEFORMATION AND MICROSTRUCTURAL EVOLUTION OF HARZBURGITE
With National Science Foundation support, Dr. Suzanne Eckert will investigate pottery and stone tool production during the Polynesian Plain Ware Period on Tutuila Island, American Samoa. Although ethnographic Polynesia is one of the model socie
MAKING POTS AND BREAKING ROCKS: UNDERSTANDING THE ORGANIZATION OF CRAFT PRODUCTION IN ANCESTRAL POLYNESIAN SOCIETY ON TUTUILA ISLAND, AMERICAN SAMOA
One of the basic tenets of plate tectonics is that quasi-rigid plates traverse the surface of the Earth, with significant deformations confined to regions near plate boundaries. While this idea works well in the oceans, it has had to be modifie
Strength of continental lithosphere in western China from seismic body wave studies
This Research award in the Inorganic, Bioinorganic and Organometallic Chemistry program supports work by Professor Claudia Turro at The Ohio State  University to carry out fundamental/basic studies on ligand-loss photochemistry of ruthenium com
(ARRA) Design, synthesis, and photochemistry of new Ru(II) complexes as potential photo-cisplatin analogs
On any given day, approximately 15-30 volcanoes worldwide are either in eruption of show strong signs of unrest (e.g., anomalously high rates of seismic activity, ground deformation, or gas emissions). Volcanic activity, including high-altitude
Collaborative Research: Toward an Understanding of Magmatic and Seismogenic Processes Beneath Quiescently Active Volcanoes
The Salton Trough/Imperial Valley in Southern California spans the transition from strike-slip faulting within the San Andreas Fault system to oceanic spreading within the Gulf of California.  The region exhibits a wide range of deformation beh
DEFORMATION WITHIN THE SALTON TROUGH AS IMAGED WITH INSAR TIME SERIES ANALYSIS
The Inorganic, Bioinorganic and Organometallic Chemistry Program supports the research of Professor Douglas Vander Griend of Calvin College for the in situ characterization of multi-component chemical solutions. Equilibrium Restricted Factor An
RUI: In situ spectroscopic and thermodynamic characterization of the molecular organiztion that leads to supramolecular structures, nanomachines, and thermochromic materials
The overall purpose of this project is to determine the surficial response to lithospheric removal in the Puna Plateau of NW Argenitna. Why is this important? Because we want to understand how the Earth's surface responds to deep (mantle) proce
Collaborative Research:  In Pursuit of Missing Andean Lithosphere:  Constraining Late Cenzoic Crust-mantle Processes in the Puna Plateau, Central Andes.
'This project is studying the early history of the geological boundary zone between the Pacific and North America plates in northwestern Mexico. The peninsula of Baja California lies on the Pacific plate, and the rest of Mexico belongs to the
Initiation of the Pacific-North America Plate Boundary in NW Mexico
Title: Aptamer-Based Colorimetric Test Kit for Biological Contamination Detection Abstract Based on a known DNA aptamer, in Phase I we intend to develop a colorimetric test strip sensor for B. thuringiensis spores (anthrax simulant), to demonst
Aptamer-Based Colorimetric Test Kit for Biological Contamination Detection
This Small Business Innovation Research (SBIR) Phase I project will investigate the ability of a device technology currently in development to prevent the intrusion of infection-causing microorganisms into surgery sites via the airborne vector.
Air Barrier System to reduce contamination of wounds during
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  This Small Business Innovation Research Phase I project will involve the development of a noninvasive intracranial pressure (ICP) monitor based o
SBIR Phase I: Non-invasive Intracranial Pressure Monitor
This Small Business Innovation Research Phase I project will research and develop selective chemical probes for use in froth flotation systems. Sulfide mineral froth flotation is a solid-solid separations process which dominates all other metho
SBIR Phase I: Selective Chemical Probes for Measurement of Flotation Collector Reagents in Sulfidic Ore Beneficiation
This Small Business Innovation Research Phase I research project develops a cost effective solution to the sewer overflow hazard within combined sewer systems and sanitary sewer systems. Specifically, the complexity and dynamic nature of the wa
SBIR Phase I: Dynamic Predictive Maintenance System for Mitigating CSO & SSO
This Small Business Innovation Research (SBIR) Phase I project aims to develop the next generation of vascular embolization coils using proprietary shape memory polymer (SMP) technology. Coils are used to occlude or isolate vessels for treatmen
SBIR Phase I: Development of novel SMP-based embolic coils
Study on Algorithms and Applications of Centroidal Voronoi Tessellations PROJECT SUMMARY  Centroidal Voronoi tessellations (CVTs) are special Voronoi tessellations having the property that the generators of the Voronoi tessellations are also th
Study on Algorithms and Applications of Centroidal Voronoi Tessellations
The Ohio State University, in partnership with Columbus State Community College, STEMColumbus, and the Ohio STEM Learning Network, will develop a Geoscience Awareness Program (GAP) targeted at underrepresented minority students at five academic
(ARRA) Geosciences awareness programs-bringing the pathway-track 1
CIF:Small:Collaborative Research: Signal Design for Low-Complexity Active Sensing
The adequate numerical treatment of free boundary problems exhibiting disparate scales is a formidable mathematical and computational challenge where the geometry plays a crucial role. Modern algorithms should be able to optimize and balance th
SPACE AND TIME ADAPTIVITY FOR MOVING AND FREE BOUNDARY PROBLEMS
Non-Newtonian fluids or complex fluids are abundant in our daily lives. Examples of such fluids include molten plastics, engine oils with polymeric additives, paints, egg white and blood. Breakthrough technology can come from experiments or thr
Novel Numerical Techniques for Complex Fluids Modeling
Native American Housing Block Grant Formula - Acquisition - New Housing
Cahuilla 2008 ARRA Formula - New Construction
Modernization of 1937 Act Housing [202 (1)]:  Mutual Help Project 90-12 & 90-13 Fifteen (15) Bathroom Renovation Project: Mitigate construction defects on up to thirteen (13) units to improve quality of substandard units.  Mutual Help Project 9
Modernization of 1937 Act Housing [202 (1)]
CIHA originally planned to purchase land with this funding. However, difficulties in acquiring suitable property have compelled us to reconsider the highest and best use of these funds.  CIHA has amended the 2008 ARRA Grant to uitize the fundin
Native American Housing Block Grant, Formula- New construction, acquisition, rehab. including energy effiency, conservation and infrastrucure development.
Native American Housing Block Grant, formula - New construction, acquisition, rehabilitation including energy efficiency and conservation, and infrastructure development.
2008 ARRA Infrastructure, Energy Efficiency & minor Home Repair Project
Construction materials and masonry for a single family home located in the Hannahville Indian Community.
LEECH LAKE BAND OF OJIBWE HOUSING AUTHORITY
Improve the quality of units by renovating 1937 Act units, addressing homelessness by completing a 3 bedroom homeless shelter and a 4 bedroom homeless shelter for veterans and developing a homeownership program to increase homeownership opportu
Leech Lake Housing Authority Renovation Program
NATIVE AMERICAN HOUSING BLOCK  GRANT(FORMULA) RECOVERY ACT FUNDS
Native American Housing Block Grant Formula - New energy efficient construction as a Low Income Housing Tax Credit project to be funded by investor as well.
Native American Housing Block Grant, Formula, Construction, Rehabilitation, including energy efficiency and administration
Grant Number: 08-SH-36-59420.  Stimulus monies are to be used for new construction of four (4) Single Family, Scattered Site Homebuyer Units for Low-Income, Native families.  The intent is to assist the community members in obtaining homeowners
Seneca Nation Housing Authority Formula Stimulus Homebuyer Program
HOUSING AUTHORITY OF THE PONCA TRIBE OF INDIANS OF OKLAHOMA
Native American Housing block Grant, Formula - New construction, acquisition, rehabilitation including energy efficiency and conservation, and infrastructure development
Rehabilitation of low income housing and IHA Office. Administration of project
Native American Housing Block grant, Formula-Rehabilitation
the Award was a grant under the Native American Housing Block Grant, Formula-New Construction acquisition, rehabilitation including energy efficiency and conservation, and infrastructure development.
2008 ARRA Elder Rental Housing Construction Project
This project is for the purposes of preserving affordable housing stock that is privately owned.  It will allow for YNHA to provide grants and zero percent loans to homeowners who have deferred maintenance issues on their homes and need to have
NATIVE VILLAGE OF BARROW INUPIAT TRADITIONAL GOVERNMENT
Indian Housing Block Grant- NAHASDA. 1 New Construction, 1 Renovation, 12 Emergency Repairs.
Native American Houisng Block Grant, Formula - New construction, acquisition, rehabilitation including energy efficiency and conservation, and infrastructure development
Native American Housing Assistance and Self Determination Act (NAHASDA) funding for housing imporvement for Indian People
BIG VALLEY RANCHERIA/BAND OF POMO INDIANS
CLOVERDALE RANCHERIA OF POMO INDIANS OF CALIFORNIA
Fiscal Year 2008 Indian Housing Plan (IHP) Amendment
Housing rehabilitation and home purchase assistance for income eligible tribal members
Rehabilitation and Down Payment Assistance
KASHIA BAND OF POMO INDIANS OF THE STEWARTS POINT RANCHERIA
Native American Housing Block Grants (Formula) Recovery
Housing Rehabilitation for Tribal Member home
Indian Housing Block Grant used to construct an energy efficient duples for the purpose of providing decent affordable housing to tribal members.
This is an expantion of a current Rehab and Weatherization program that the Tribe currently administers. This program will (1) Hire a Rehab & Weatherization Specialist. (2) Service a total of 23 members with Rehabilitation & Weatherization of t
MATCH-E-BE-NASH-SHE-WISH BAND OF POTTAWATOMI INDIANS
Rehabilitation of Member Owned Homes and Homubuyer Education Classes
SAGINAW CHIPPEWA INDIAN TRIBAL GOVERNMENT
Native American Housing Blcok Grant, Formula-New constriction, acquisition, rehabilitation including energy efficiency and conversation, and infrastructure development
Cayuga Nation - The American Recovery and Reinvestment Act (Recovery Act) of 2009 - Allocation of pro-rata share to the Indian Housing Block Grant (IHBG) formula allocation for FY 2008.  FY 2008 Grant $369,328 x Pro-rata Share 43% = FY 2009 Rec
NATIVE AMERICAN HOUSING ASSISTANCE & SELF-DETERMINATION GRANT WILL CONTINUE TO ASSIST THE HOUSING AUTHORITY WITH THE MAINTENANCE OF THE LOW INCOME RENTAL HOUSING UNITS.
NATIVE AMERICAN HOUSING BLOCK GRANTS (FORMULA) RECOVERY ACT FUNDED
COW CREEK BAND OF UMPQUA TRIBE OF INDIANS
Native American Housing Block Grant, Formula-New construction,acquisition, rehabilitation including energy efficiency and conservation, and infrastructure development.
Myrtle Creek Housing Development Project
We will leverage these funds with other funding such as Indian Community Development Block Grant, USDA Housing Preservation Grant, Washington State Dept. of Commerce Weatherization funds, BIA Housing Improvement Program funds, USDA 504 and trib
Housing Rehabilitation and Energy Efficiency for Existing Homeowners.
Collaborative Research: Tribologically Durable UHMWPE Nanocomposites for Total Joint Replacements: Nano-mechanics and Bio-tribological Modeling  This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).
Collaborative Research: Tribologically Durable UHMWPE Nanocomposites for Total Joint Replacements: Nano-mechanics and Bio-tribological Modeling
The 8000-ft deep Homestake Mine in Lead, SD is the proposed site for a Deep Underground Science and Engineering Laboratory (DUSEL). It is being operated today as the Sanford Underground Science and Engineering Laboratory (SUSEL) while it is bei
ARRA Collaborative Research: Fiber-Optic Strain Monitoring of Rock Masses in Large, Underground Facilities
There is a high degree of interest in using organic thin films for lightweight, rugged, and flexible solar cells. Conjugated polymers are being considered as a major enabler of such applications. Due to a small dielectric constant in these orga
Free-Standing All-Nanoparticle Thin Fibers:  A Novel Building Block for Organic Photovoltaic Applications
The major factor in the solar wind that controls magnetospheric activity is the direction and magnitude of the interplanetary magnetic field (IMF). When the IMF is relatively small, and the mach number of the solar wind flow is large, the magne
Solar Wind Energy Transfer to Geospace during Periods with Large Transverse Interplanetary Magnetic Field (IMF)
The objective of this research is to develop a spectrum management framework for cognitive radio ad hoc networks. The project investigates the challenges posed by the distributed multi-hop architecture, the dynamic network topology, and the fre
ARRA: SPECTRUM MANAGEMENT IN COGNITIVE RADIO AD HOC NETWORKS
Continuing his previous work on elliptic stable maps, the PI's near-term objective is to complete his joint work on the structures of the moduli spaces of genus-two stable maps; then strengthen the results that they already obtained in high-gen
This project conducts research in the area of dispersive partial differential equations. Its intent is twofold. On the one hand, it is concerned with specific questions about the behavior of solutions to certain dispersive equations. On the oth
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  The PI plans to investigate certain concrete problems in Operator Theory, mostly centered around Toeplitz operators and matrices as well as their
Topics in Operator Theory with Applications to Random Matrices
State-of-the-art chips use low-k materials to form the insulator between interconnect lines. The use of low-k materials reduces capacitance, which in turn reduces the propagation delay between the transistor gates in a chip. To reduce delay, ea
ARRA: PHYSICAL MODELING OF LOW-K DIELECTRIC BREAKDOWN AND THE ESTIMATION OF FULL CHIP LIFETIME
Significant seasonal changes in arctic sea ice have been observed in recent years, characterized by unprecedented summer melt-back because of the lengthening of the summer melt season with earlier melt and later freeze onsets. As summer sea ice
ARRA supplemental funding for Community Services Block Grant program will be used to enhance services for the agency's clients in the child welfare system. Services will include family stability, emergency support, education, employment, financ
American Recovery and Reinvestment Act of 2009 (ARRA) supplmental funding for the Community Services Block Grant (CSBG) was allocated and granted to a network of eligible entities to support locally designed strategies to alleviate the causes a
Purchase raw food and supplies for distribution of nutritional meals at agency and home deliveries for 100-125 senior citizens
2009 Community Services Block Grant American Recovery and Reinvestment Act Funding: The purpose of the Community Services Block Grant American Recovery and Reinvestment Act funding is to carry out activities under the Community Services Block G
Child Care Development Fund:  To promote the economic and social well being of children, youth, families and communities by providing child care assistance for low income families.
The Virgin Islands Child Care and Development Block Grant will be used for the purpose of enhancing the availability and access to quality early care and education for children ages 0-5.  The CCDF ARRA grant will also allow the Virgin Islands t
Office of Child Care and Regulatory Services ARRA Project
Knud Hansen Complex Bldg. A 1303 Hospital Ground
Changes in the magnitude and seasonality of Arctic summer vegetation production over the past several decades have been documented. These changes will likely accelerate and have consequences for the entire Arctic terrestrial system, in particul
Collaborative Research: Seasonality of circumpolar tundra - ocean and atmosphere controls and effects on energy and carbon budgets
This project is a request for funds to buy scientific equipment for the University of Minnesota's research vessel the Blue Heron.  We intend to purchase acoustic releases for scientific moorings deployed on the Great Lakes, floatation for the s
Oceanographic Instrumentation, R/V Blue Heron 2009
I-90/Snoqualmie Summit to Hyak WB - Dowel Bar Retrofit/Concrete Rehab
A significant missing component in paleo-reconstructions of GIS behavior has been the lack of an unambiguous ice sheet tracer. The development of such a tracer for the Greenland Ice Sheet (GIS) retreat and aerial extent is proposed using terrig
ARRA Collaborative Research: Development of paleo-proxy to test the sensitivity of the southern Greenland Ice Sheet to future warming
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  This grant supports research on late Pleistocene and Holocene convective and hydrologic variability in Indonesia through the recovery and analysi
This study will quantitatively reconstruct deep ocean carbonate chemistry changes across the Paleocene-Eocene thermal maximum to determine the degree of ocean acidification during a past period of high CO2 and extreme warming. The PIs will gene
Collaborative Research: Reconstructing deep sea acidification during the Paleocene-Eocene Thermal Maximum
The objective of this research is to develop an automated design environment for enabling the integration of emerging nanoscale silicon photonic optical interconnect device technologies in next-generation multicore computing architectures. The
Nanopotonic Interconnect CAD: Automated Design for Nanophotonic Enabled Interconnect in Multicore Architectures
Domain specific multi-core processors (DSMPs) are aimed at high performance embedded system applications (image/signal processing, networking, graphics, medical instrumentation, and so on). DSMPs incorporate several architectural innovations in
System-level Design of Streaming Applications on Domain Specific Multi-core Processors
The principal investigator proposes to work on three problems in the geometry of Banach spaces with a strong set theoretic and/or combinatorial flavor. Firstly, the principal investigator proposes to work on the classification problem of comple
ARRA SET THEORY AND THE GEOMETRY OF BANACH SPACES
A key distinction of this project is its transformative approach to simulation of complex multi-scale phenomena modeled with PDEs and particle-in-cell techniques. Our team combines expertise in discrete-event simulations, high-performance compu
VHPL: Virtual Hybrid Particle Laboratory for End-to-End Simulation of High-Beta Plasmas
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  TECHNICAL SUMMARY Atomic clusters containing a few to few hundred atoms exhibit dramatic size-dependent chemical and physical properties and form
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  This collaborative investigation into the forest atmosphere photochemistry will apply a unique set of collaborative approaches, focused on the ch
Collaborative Research: Program for Research on Oxidants: Photochemistry Emissions and Transport (PROPHET) 2009--Community Atmosphere-Biosphere INteractions EXperiment (CABINEX)
It is now well known that forests emit organic compounds (BVOCs) that impact the physical (e.g. aerosols) and chemical (e.g. ozone) composition of the overlying atmosphere, and that this in turn impacts forest productivity.  However, recent mea
PROPHET (Program for Research on Oxidants: PHotochemistry, Emissions and Transport) and the FASET (Forest Accelerated Succession ExperimenT) facilities, experience and human resources
Collaborative Research: Program for Research on Oxidants: Photochemistry Emissions and Transport (PROPHET) 2009- Community Atmosphere-Biosphere Interactions Experiment (CABINEX)
- gadgets developed by the P.I. using symplectic geometry associated with BLFs which conjecturally recapture the Seiberg-Witten invariants. The P.I. will use conceptual tools from symplectic topology to compute Floer-theoretic invariants for t
Lefschetz fibrations, Floer homology and the smooth topology of 4-manifolds
Collaborative Research: Petascale Computing, Visualization, and Science Discovery of Turbulent Sooting Flames  Energy efficiency, the environment, and human health can be affected by combustion-generated soot, so controlling soot is a major tec
Collaborative Research: Petascale Computing, Visualization, and Science Discovery of Turbulent Sooting Flames
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  This project is focused on implementing novel methods for uncertainty quantification in the context of modeling carbon sequestration. Significant
Collaborative Proposal:  Uncertainty quantification for petascale simulation of carbon sequestration through fast ultra-scaleable stochastic finite element methods
This award will enable the initiation of work on techniques for better climate simulation in conjunction with personnel at NCAR in Boulder Colorado.  In this work, the PI at UW and personnel from his research group will interact with NCAR resea
Collaborative Research:  A Multiscale Unified Simulation Environment for Geoscientific Applications.
This proposal addresses the most challenging problems of very-high-resolution Numerical Weather Prediction, obtaining the optimal state estimations for initializing ensembles of predictions by assimilating the highest volume of weather observat
Collaborative Research: Enabling Petascale Ensemble-Based Data Assimilation for the Numerical Analysis and Prediction of High-Impact Weather
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). This proposal seeks to address a wide range of research challenges involving OLAP (OnLine Analytical Processing). This collaborative project is co
III: Medium: Collaborative Research: Towards On-Line Analytical Mining of Heterogeneous Information Networks
Great progress has been made in recent years in detecting massive planets orbiting other stars. These exciting discoveries are an important step toward understanding the evolution of other solar systems and whether or not they may harbor life.
Collaborative Research: An Ultrastable Blue Astro Comb for Exoplanet and Cosmology Research
Although much progress has been made on the theoretical understanding of cryptographic protocols, security vulnerabilities are still found in protocol standards and implementations long after they have been accepted and fielded. As in the case
TC: Medium: Collaborative Research: Unification Laboratory: Increasing the Power of Cryptographic Protocal Analysis Tools
The fundamental question being examined is how to transfer information over wireless networks. Wireless networks differ from wireline networks due to the phenomenon of superposition. Signals transmitted by different transmitters are attenuated
NeTS Medium: Collaborative Research: MIMO-Pipe Modeling, Scheduling and Delay Analysis in Multi-hop MIMO Networks
NeTS: Medium:Collaborative Research: Cooperative beamforming for efficient and secure wireless communication
Arts and the American Recovery & Reinvestment Act of 2009.
Arts and the American Recovery & Reinvestment Act 0f 2009
MARSH A BREEDING GROUND FOR NEW PERFORMANCE, THE
PASADENA PLAYHOUSE STATE THEATRE OF CALIFORNIA, INC. THE
To support the preservation of jobs that are threatened by declines in philanthropic and other support during the current economic downturn, as described in your application (A09-906290) and the approved projected budget.
Desert dust aerosols impact the climate and biogeochemistry. This project seeks to improve our understanding of the spatial and temporal variability of desert dust and desert response to climate and human perturbation. It will address the follo
MINERAL AEROSOL VARIABILITY IN THE ANTHROPOCENE
Lithium ion batteries have been recognized as a critical technology to enable the advanced electric vehicles (EV) and hybrid electric vehicles (HEV). An obstacle of the traditional Li-ion batteries to the EV/HEV applications is their low peak p
Novel Electroanalytical Techniques for Phase Transformation Electrodes
Microfluidic 'Labs on a Chip' have transformed a wide variety of biochemical assays by shrinking the contents of an analytical chemistry laboratory down to a few square centimeters. Scaling down even further, ultimately to assays at the single-
ARRA: EQUIPMENT GRANT FOR INTERFACIAL VELOCIMETRY AND 3D LIQUID-PHASE THEMOMETRY IN MICROFLUIDIC DEVICES
The use of self-organizing liquid crystals is a method of enhancing performance of organic polymers through structural and chemical control on the nanometer scale. Functional nanostructured polymer materials based on lyotropic (i.e., amphiphili
Reaction Directed Polymer Nanostructures through Self-Assembly and Photopolymerization
This exploratory project involves the first field test of a new, Relaxed Eddy Accumulation instrument for measuring concentrations and fluxes of Volatile Organic Compounds (VOCs) in a long-term, unattended operational mode under limited infrast
EAGER:   MIXING RATIO AND FLUX MEASUREMENTS OF VOLATILE ORGANIC COMPOUNDS DURING BEARPEX 2009 USING A PROTABLE SELF-SUFFICIENT REA-GC-FID SYSTEM
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  Golden 0934721 University of Utah  Funds are provided to develop methods of electromagnetically monitoring the internal state of sea ice, the the
CMG COLLABORATIVE RESEARCH: MATHEMATICS & ELECTROMAGNETICS FOR MONITORING TRANSPORT PROCESSES IN SEA ICE
Towson University is one of Maryland's premier educators of new teachers. Responding to a nationwide concern about the future of Science, Technology, Engineering and Mathematics (STEM) education, Towson University and the whole University Syste
TU Robert Noyce Teacher Scholarship Program
NATIONAL FEDERATION OF COMMUNITY BROADCASTERS INC.
WASHINGTON, DC INTERNATIONAL FILM FESTIVAL, INC.
This engineering education research award to Michigan Technological University will develop problem based learning modules that integrate sustainability and sustainable design into three mechanical engineering courses spanning the sophomore thr
Weaving Threads of Sustainability into the Fabric of the Mechanical Engineering Curriculum: Impacting the Fundamental Manner in which Students Solve Problems
This engineering education research award to Clemson University in collaboration with Purdue University and Virginia Polytechnic Institute and State University will develop a comprehensive knowledge management system and visualization methods f
Collaborative Research: Interactive Knowledge Networks for Engineering Education Research (iKNEER)
This project will undertake basic research aimed at controlling how electrical charge moves through photovoltaic devices. The objective is to produce synthetic electrets - non-conductive materials that are the electrostatic equivalent of magnet
EAGER: Bioinspired Electrets for Solar-Energy-Conservation Applications
to support the preservation of jobs that are threatened by declines in philanthropic and other support during the current economic downturn.
Arts and the American  Recovery &  Reinvestment  Act of 2009
Public demand for safer Li-ion batteries (LIBs) with lower cost and higher energy density has driven extensive research efforts in the synthesis of new electrodes and electrolytes that are less hazardous (non-toxic, non-flammable), have longer
Chemically Tunable Graphene-Based Polymer Nanocomposites as Electrode Materials for Safe, High-Performance Lithium-Ion Batteries
The research objective of this award is to develop a novel synthesis process to produce graphene nanoribbons (GNRs) with width controlled at a resolution of 1 nm and crystallographic-orientation (CO) controlled at a resolution of 50 (with contr
EAGER: Graphene-Nanoribbons of Controlled Width and Crystallographic-Orientation
US-93; MP 104.1 to MP 106 (Ranch Road Section)
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). Scaling Up is a program of research and development that will enable virtual organizations in the Earth sciences to scale to massive interdiscipli
Collaborative Research: CDI-Type II: Scaling Up: Introducing Commoditized Governance into Community Earth Science Modeling
Birth Defects, Genetic Disorders & Developmental Disorders Research
To support the preservation of arts jobs that are threatened by the decline in philanthropic and other support during the current economic crises.
To support the  preservation of jobs  that are threatened  by declines in  philanthropic and  other support  during the current  economic  downturn.
This project examines the importance of intermediate physical organizations in the transformation of loose networks of researchers into sustainable cyber-based virtual organizations in emerging fields of interdisciplinary science and engineerin
VOSS: Transforming Loose Networks into Sustainable Interdisciplinary Virtual Organizations
A request is made to fund additional and back-up instrumentation for the R/V Blue Heron, an 86 foot Coastal vessel owned by the University of Minnesota and operated by the Large Lakes Observatory as part of the University-National Oceanographic
Oceanographic Instrumentation, R/V Blue Heron, 2009
To support the preservation of jobs that are threatened by decline in philanthropic and other support during the current economic downturn.
Arts and the American Recovery & Reinvestment Act - to support the preservation of jobs that are threatened by declines in philanthropic and other support during the economic downturn
MINNEAPOLIS SOCIETY OF FINE ARTS, THE (INC)
The Arts and American Recovery and Reinvestment Act of 2009
ARRA: NSF GRADUATE RESEARCH FELLOWSHIP PROGRAM
The National Science Foundation aims to ensure the vitality of the human resource base of science, technology, engineering, and mathematics in the United States and to reinforce its diversity by offering approximately 1,654 graduate fellowships
Polyploidy (whole genome duplication) is one of the most important genetic phenomena in plants. Immediately after its formation, a polyploid plant can be identified simply by counting its chromosomes, because it has twice as many as a diploid.
EAGER: ESTIMATING THE PREVALENCE OF POLYPLOIDY IN THE PHASEOLOID LEGUMES
The objective of this project is to organize a workshop that will provide an opportunity to present the state-of-the-art in the area of Dynamic Route Guidance and Coordinated Traffic Control. The workshop scope is to determine the most importan
NSF Workshop on Dynamic Route Guidance and Coordinated Traffic Control
To support the preservation of jobs that are threatened by declines in philanthropic and other support during the current economic downturn, as described in our application (A09-904308) and the approved project budget.
To support the preservation of jobs that are threatened by the declines in philanthropic and other support during the current economic downturn.
US 95 From 1.63 miles south Jackass Flat to 0.62 miles north SR 160.
is preferentially supported by more controlled processes that depend on a part of the brain called the dorsolateral prefrontal cortex. Recent research in cognitive genetics has identified variants of genes that influence neural activity in the
Collaborative Research: Genetics of Moral Cognition
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).    The Principal Investigator (PI) plans to develop a Geospace Science Center which will provide control, operation, and science integration of th
This engineering education research CAREER award to Virginia Polytechnic Institute and State University will advance fundamental knowledge of how professional engineering practices have changed due to globalization and how this has impacted eng
CAREER: INVESTIGATING GLOBAL ENGINEERING WORK PRACTICES TO PREPARE 21st CENTURY ENGINEERS
LINCOLN CENTER FOR THE PERFORMING ARTS, INC
SAUTEE NACOOCHEE COMMUNITY ASSOCIATION INC
To support the preservation of jobs that are threatened by declines in philanthropic support during the economic downturn.
To Support the preservation of jobs that are threatened by declines in philanthropic and other support during the current economic downturn.
To support the preservation of jobs which are threatened by declines in philanthropic and other support during the economic downturn.
CENTER FOR ARTS & SCIENCES OF WEST VIRGINIA, INC
To support the preservation of jobs that are threatened by declines in philanthrophic and other support during the current economic downturn.
The Clay Center for the Arts and Sciences
The Arts & the American Recovery and Reinvestment Act of 2009
The objective of this project is to create a framework for collection of life cycle inventory data for fiber reinforced polymer composite infrastructure materials. Currently, advancements are being made towards innovative, alternative materials
EAGER: Developing a Systematic Method for Collection of Life Cycle Inventory (LCI) Datafor Infrastructure Fiber Reinforced Polymer Composites
This  award is to study the potential of novel computational algorithms for impacting the potential of engineering simulations to take greater advantage of upcoming high performance computing architectures.  The award will provide funds for PI
Achieving Petaflops Level Parallelism for Simulation-Based Engineering Problems in Fluid Dynamics.
To support arts projects and activities which preserve jobs in the nonprofit arts sector threatened by declines in philanthropic and other support during the current economic downturn.
The objective of this research is to develop general-purpose algorithms for automatically identifying principles underlying observed phenomena, in fields ranging from physics to biology. For centuries, scientists have attempted to identify and
CDI TYPE I: DISTILLING FREEFORM NATURAL LAWS FROM EXPERIMENTAL DATA
SOUTH MOBILE COUNTY EDUCATIONAL CENTER, INC.
To support preservation of jobs that are threatened by declines in philanthropic and other support during the current economic downturn.
Arts & American Recovery & Reinvestment Act of 2009
To support the preservation of jobs that are threatened by declines in philanthropy and other support during the current economic downturn
The researchers will develop model(s) of the lifecycles of virtual multidisciplinary scientific teams using the facilities of the National High Magnetic Field Laboratory built from data collected through descriptive multiple-case studies, groun
VOSS: Virtual Scientific Teams: Life-Cycle Formation and Long-Term Scientific Collaboration
To support the preservation of jobs that are threatened by declines in philanthropic and other support during the current economic downturn.  FINAL REPORT.  All funds
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). This research applies argumentation theory to large-scale (hundreds to thousands of users), asynchronous, and geographically dispersed virtual org
VOSS: Empirical Analysis of Large-Scale Argumentation
This proposal requests funds to develop a series of twenty engaging, multi-media case studies of ocean scientists addressing the Broader Impacts activities of their research. This effort will involve representatives of all Centers for Ocean Sci
Enhanced Engagement by Scientists for Broader Societal Impacts
To support the preservation of jobs that are theatened by declines in philanthropic and other support during the current economic downturn.
Arts and the American Recovery & Reinventment Act of 2009
To support the preservation of jobs that are threatened by declines in philanthropic and other support during the current economic downturn, as described in application A09-904385 and the approved project budget.
Arts and the American Recovery Act of 2009
To support the preservation of jobs that are threatened by declines in philanthropic and other support during the current economic downturn, as described in application (A09-905988) and the approved budget.
The transformative accomplishment of this research will be the development of single molecule strategies to detect, quantify, and map multiple targets in a single nucleosome simultaneously at any locus within a living cell. These single molecul
Single Molecule Tools for Evaluating Histone Modifications in Single Living Cells
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  The investigator will utilize satellite altimetry data to identify the specific ocean source responsible for thermospheric Acoustic Gravity Wave
EAGER: Exploration of the Ocean Surface for the Source of Arecibo's Continuous Thermospheric Gravity Waves
National Science Foundation Graduate Research Fellowships in support of doctoral students at Cornell University.
Under the term of this award, the National Astronomy and Ionosphere Center (NAIC) will perform infrastructure improvements to facilities of the Arecibo Observatory in Arecibo, Puerto Rico, at which the cornerstone research instrument is the 100
National Astronomy and Ionosphere Center Proposal for Renewal and Reinvestment Funds
Dogs descended from Eurasian gray wolves, but where and how this process occurred is poorly understood. Much genetic research has focused on breed dogs, but the diverse populations of semi-feral 'village' dogs are likely an important key for un
EAGER: GENOME-WIDE DIVERSITY IN VILLAGE DOGS: UNCOVERING THE HISTORY OF DOG DOMESTICATION, THE GENETICS OF NATURAL DOG POPULATIONS, AND CONSEQUENCES OF ARTIFICIAL SELECTION IN BREED DOGS
This engineering education award to the Virginia Polytechnic Institute and State University will develop innovative new graduate degree programs in mechanical engineering that are customized to the needs and strengths of veterans. A particular
VETERANS@VT: A Program for Recruiting, Transitioning, and Supporting Veterans to Graduate Programs in Engineering and Beyond to Civilian Careers
The objective of this EAGER research is to demonstrate the feasibility of using synthetic fly ash glass as a model for systematic studies of fly ash reactivity instead of using real fly ash. It will demonstrate that synthetic fly ash specimens
EAGER Collaborative Research: Development of Synthetic Fly Ash Glass as a Model System for Investigating Fly Ash Reactivity
TENNESSEE WILLIAMS-NEW ORLEANS LITERARY FESTIVAL, INC, THE
To support the preservation of jobs that are threatened by declines in philanthropic and other support during the economic downturn
Arts & the American Recovery and Reinvestment Act of 2009
Arts and American Recovery and Reinvestment Act
ARTS AND THE AMERICAN RECOVERY & REINVESTMENT ACT OF 2009
ALLIANCE FOR CALIFORNIA TRADITIONAL ARTS
The objective of this workshop is to convene experts from government, non-profit, industry and academic organizations to explore various aspects of the potential afforded by ITS technologies as they relate to improvements in vehicular traffic,
ARRA:  NSF Workshop: The future of intelligent transportation systems and its implication with regard to mobility and sustainability
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).A request is made to fund additional and back-up instrumentation on the R/V Thomas Thompson, a 274? general purpose Global research vessel operated
CULTURAL RESOURCES, NORTH CAROLINA DEPARTMENT OF
METROPOLITAN ARTS COUNCIL OF GREATER KANSAS CITY
To support the preservation of jobs that are threatened by declines in philanthropic and other support during the current economic downtown.
Arts and the American Recovery and Reinvestment Act
HEALTH AND SOCIAL SERVICES, ALASKA DEPARTMENT OF
ARRA provided funding for Home Delivered Nutrition Services. Established in 1978 under the Older Americans Act, the program provides meals to seniors who are homebound.
ARRA provided funding for Home-Delivered Nutrition Services.  Established in 1978 under the Older Americans Act, the program provides meals to seniors who are homebound.
ARRA provided funding for Congregate Nutrition Services.  Established in 1972 under the Older Americans Act, the program provides meals to older Americans in congregate facilities such as senior centers, adult day centers, and faith-based setti
ARRA provided funding for Congregate Nutrition Services. Established in 1972 under the Older Americans Act, the program provides meals to Older Americans in congregate facilities such as senior centers, adult day centers, and faith based settin
Home Delivered Nutrition Services ARRA - This program provides funds for home-delivered nutritional services.
ARRA provided funding for Home-Delivered Services.  Established in 1978 under the Older Americans Act, the program provides meals to seniors who are homebound.
HUMAN SERVICES, NORTH DAKOTA DEPARTMENT OF
ARRA provided funding for home-delivered nutrition services.  Established in 1972 under the Older Americans Act, the program provides meals to older Americans who are homebound.
This Senior Nutrition Program is to provide congregate meals for the elderly. The program was built on the Congregate Meals program authorized by Title III-C-1 of the Older American's Act.  However, the Administration on Aging has limited the A
SOCIAL SERVICES, SOUTH DAKOTA DEPARTMENT OF
ARRA provided funding for Congregate Nutrition Services. Established in 1972 under the Older Americans Act, the program provides meals to older Americans in congregate facilities such as senior centers, adult day centers, and faith-based settin
Title III C1 Nutrition Services ARRA provide funding for Congregate Nutrition Services.  Established in 1972 under the Older Americans Act, the program provides meals to older Aamerican in congregate facilites such as senior centers, adult day
2009 T3C1_ARRA Congregated Nutrition Services
This award allows the USGS and related seismic networks to monitor the state of health of the Quanterra Q330 seismic instrument now being deployed. This will allow  earthquake monitoring networks to become more reliable.
The purpose of this task order is to acquire natural color imagery, thermal infrared (IR) imagery, and related products to be used for a leak detection study of controlled canal reaches that it operates in the Lower Colorado Region.  Approximat
Surveying and Mapping (except Geophysical) Services
Native American Housing Block Grant, Competitive ? NAHASDA eligible activities including acquisition, new construction, rehabilitation of affordable housing, site improvement, development and rehabilitation of utilities and infrastructure, util
NATIVE AMERICAN HOUSING BLOCK GRANT - COMPETITIVE (NEW CONSTRUCTION)
Cahuilla, LaJolla, Santa Rosa, Torres Martinez
New Construction of single and Multi-family dwelling units
To provide infrastructure for a subdvision being developed by Nambe Pueblo Housing Entity.  The specific infrastructure items to be constructed include a roadway, retaining wall and sidewalks for the Buffalo Range Subdivision.  The Buffalo Rang
Rehab 21 units in the Pueblo core area of Ohkay Owingeh.
Native American Housing Block Grant, Competitive- Construction of a new Housing office building.
Native American Housing Block grant, Competitive-New construction
Native American Housing Block Grant, Competitive - NAHASDA-eligible activities including acquisition, new construction, rehabilitation of affordable housing, site improvement, development and rehabilitation of utilities and infrastructure, util
NE Longhouses Rental Housing & Community Building Construction Project
TURTLE MOUNTAIN BAND OF CHIPPEWA INDIANS
HOUSING AUTHORITY OF THE CHOCTAW NATIONS OF OKLAHOMA
Native American Housing Block Grant Formula - New Construction of Rental Housing with intended outcomes of: create new affordable rental units, provide accessibility for disabled/elderly persons, and improve energy efficiency on these new units
Recovery Act - FORMULA construction of rental housing
Native American Housing Block Grant (Formula)Recovery Act Funded
Native American Housing Block Grant (Formula) Recovery Act Funded
Vosper Place Subdivision - Single Family Homeownership Program
2008 ARRA Tower Property Infrastructure Improvement Project.
Purchase a home to used for low income native American housing.
Native American Housing Block Grant, Formula - New construction, acquisition, rehabilition including energy efficiency and conservation, and infrastructure development.
NAHBG - Formula grant to build 12 two bedroom low rent units at Ben Gay Heights in Arapaho, Wyoming
To purchase or build home for low income tribal members
Rehabilitate an exisiting housing structure for temporary low-income housing unit for displaced residents or transitional housing
Chilkat Indian Village Rehabilitation Project
ARRA Native American Housing Block Grant, Formula - rehabilitation including energy efficiency
Native American Housing Block Grant,formula-New construction,acquistion,rehabilitation including energy efficiency and conversation, and infrasstructure development
Native American Housing Block Grant,formula-Rehabilitation
GRAND TRAVERSE BAND OF OTTAWA & CHIPPEWA INDIANS
Award will go towards modernizing 1937 Act homes in the purchase of energy efficent appliances
Native American Housing Block Recovery Grant
In an attempt to provide descent safe and sanitary conditions Osage Nation is providing moderate to substantial rehabilitation to approximately 20 homeowner based units. The outcome for the selected families is to improve the environmental heal
This program will allow the construction of three new NAHASDA homebuyer units.
Ysleta del Sur Pueblo Three New NAHASDA Homes
(1) Rehab of rental housing, (2) Rehab assistance to existing homeowners, and (3) Acquisition with rehabilitation for homebuyer units.
Native American Housing Block Grant, Formula - New construction, acquisition, rehabilitation including energy efficiency and conservation, and and infrastructure development.
2008 ARRA Rental Housing Rehabilitation Project
Install energy efficient LP furnaces and programmable thermostats in 194 houses; install energy efficient water heaters in 174 houses; purchase 190 LP tanks from vendot to facilitate the purchase of LP gas from the most cost effective sources r
DTV Program, also know as the Transition from Analogo-To-Digital. Contractor was awarded 5,000 Installations (Expert Installations) in FCC Region # 1, which includes the following states: Alaska, Oregon, Washington, California, Arizona, Utah, N
DTV Program, also know as the Transition from Analogo-To-Digital. Contractor was awarded 10 DTV Walk-In Centers to be located in Wisconsin, Illinois, and Kansas. DTV Walk-In Centers are fixed loctions; the purpose of which is to educate the pop
that were able to install their TV Converter for them at no charge.
Quantum dot (QD) active regions hold potential for realizing extremely high performance semiconductor diode lasers. Unfortunately, these unique features of ideal QD active layers have not been fully realized to date. The most successful approac
ARRA High Efficiency Diode Lasers based on Nano-patterned Qunatum Dot Active Regions
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). The objective of this research award is to model the preference information embedded in natural language engineering design texts in order to iden
Linguistics-based preference information modeling for design decision-making
Currently plasmon resonances are mostly studied numerically or experimentally by using a trial-anderror approach, i.e., by probing nanoparticles with radiation of various frequencies and polarizations. The goal of this project is to advance nov
Study of Plasmon Resonances in Nanoparticles
Drinking water distribution systems are a complex, integrated system of pipes and hydraulic devices that serve as the last step in delivering treated drinking to the consumer. Distribution system operations need to satisfy multiple objectives t
Real-Time Distribution System Network Modeling and Fault Diagnosis
The PI will undertake research in harmonic analysis, and partial differential equations (PDE). In PDE, the focus is on the dynamical properties of Schrodinger evolution (SE). One subject of on-going research is dispersive estimates for SE. He w
Research in Harmonic Analysis and Partial Differential Equations
are replaced by more flexible notions, allowing to implement ideas from the classical case to a more demanding setting. These problems lie at the intersection of several major branches of mathematics and one of the main goals of this project i
ISOPERIMETRIC INEQUALITIES AND THE LARGE-SCALE GEOMETRY OF GROUPS
The PI proposes to study the theory of singularities and complexity in CR geometry. In particular the PI proposes to study the connections between his previous work on Levi-flat hypersurfaces, properties of nowhere minimal submanifolds of compl
Singularities and Complexity in CR Geometry
Positronium, with the chemical symbol Ps, is a very light form of hydrogen atom consisting only of an electron bound to an anti-electron or positron. Being composed of equal amounts of matter and antimatter, the Ps atom lives for only a fractio
Spectroscopy of Positronium Molecules and Bose-Einstein Condensates
During the 20th century (and the beginning of the 21st), a number of deep and surprising connections have been found between modular forms, elliptic curves, quadratic forms, L-functions, Galois representations, and the representation theory of
The Distribution of the Fourier Coefficients of Modular Forms and Arithmetic Applications
Objective: Nanowires' unique geometry leads to a large surface area to volume ratio, which, along with the capability of rational control in doping and heterostructure formation, can be exploited in many devices and subsystem modules for variou
Semiconductor nanowire electro-optic and photonic devices for optical communications
The main thrust of this project is to further the understanding of the global/large data behavior of solutions to certain dispersive equations at critical regularity. More precisely, the principal investigator considers global well-posedness an
Low complexity dynamical systems include symbolic systems such as Sturmian sequences and the Morse sequence; horocycle flows and other unipotent flows on spaces of algebraic origin; rational polygonal billiards and related systems such as linea
Award ended in September 2010 and all work was completed at that time.
The Community Services Block Grant Program has allocated funds to a network of eligible entities to support employment related services, which create and sustain economic growth.  Ninety-nine percent of the funding was distributed to eligible e
ARRA Supplemental Funding for the Community Services Block Grant (CSBG) Program.  The North Dakota Department of Commerce awarded each of the 7 Community Action Agencies in the state their proportional share of the 99% pass-through of the CSBG
JOB & FAMILY SERVICES, OHIO DEPARTMENT OF
$59,245,395 of the ARRA Discretionary funds will be spent during State Fiscal Year 2010 to stabilize the subsidized child care budget thus permitting the continuation of service to existing families.   $5,620,429 of the ARRA Targeted Funds for
CHILDREN AND FAMILIES, WISCONSIN DEPARTMENT OF
Title:  ARRA Supplemental Funding for the Child Care and Development Fund (CCDF); Description:  The ARRA funds of $30,493,313 have been fully expended.  Major outcomes and accomplishments, consistent with the goals of the ARRA, included creatio
2009 Child Care Subsidy and Quality Improvement
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).   Abstract   Arctic soils have large stores of carbon (C) and may act as a significant CO2 source with warming. However, the key to understanding
Collaborative Research:The Changing Seasonality of Tundra Nutrient Cycling: Implications for Ecosystem and Arctic System Functioning
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).   The majority of proxy temperature records indicate that during the early Pliocene, roughly 3 to 5 million years ago, the tropical Pacific was ch
Collaborative Research: Reconstructing the Meridional SST Gradient and Climate Conditions of the Early Pliocene
This project examines a sedimentary sequence from Lake Chalco (Central Mexico) to develop a ~50 kyr record of terrestrial climate variability in the North American tropics. The project uses proxies that reflect hydrological and thermal variabil
Pilot Project: Reconstructing tropical North American climate with the sedimentary record of Lake Chalco, Mexico
Collaborative Research: Development of paleo-proxy to test the sensitivity of the Southern Greenland Ice Sheet to future warming
Funding is provided to investigate equator-to-pole temperature differences and high-latitude seasonality during the equable climate of the Eocene Period when both were much smaller than they are today. These circumstances are difficult to expl
Collaborative Research:P2C2-Understanding the Role of a High Latitude Convective Cloud Feedback in Equable and Future Climate Dynamics
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  The Qinghai-Tibetan Plateau occupies the highest elevation on the continental Earth and is renowned for its extraordinary monsoonal climate. It i
High-resolution, quantitative records of temperature and effective precipitation for the past 25kyr from Lake Qinghai
This award supports an investigation of the deglacial record in the Gulf of Mexico, specifically the timing of the initial melting of the Laurentide Ice Sheet (LIS). The PI will use a multi-proxy approach (d18O, Mg/Ca, and Ba/Ca) to detect sali
Initial deglaciation of the Laurentide Ice Sheet: A Gulf of Mexico perspective
EBL, Fm E of the SD73 N Jct E to E of the SD73 S Jct.Near Kadoka; WBL, Fm W of the SD73 N Jct E to E of the SD73 S Jct. Near Kadoka & EBL/WBL, Fm the Jackson County Line to W of Murdo & EBL & WBL, fm
This award comes from the NSF and is designed to investigate climate change in the Near East (principally Iran).  The award funds geologic and geochemical investigations of lake sediments as a means of reconstructing droughts and monsoon variat
Hydroclimate Evolution at the Last Interglacial/Glacial Transition in Western Iran
The push toward heterogeneous architectures to increase performance, while reducing energy consumption creates considerable challenges for software development. For example, programmers must make non-trivial decisions about when to use special
ARRA: QAMELEON HARDWARE/SOFTWARE CO-OPERATIVE AUTOMATED TUNING FOR HETEROGENEOUS ARCHITECTURES
'The objective of this research is to address the computational challenges in multi-core power distribution design by leveraging recent advances in single-instruction multiple-data (SIMD) graphics processing units (GPUs). The approach is to dev
Thermal-Aware GPU-Based Design Engine for On-Chip Power Delivery in Power-Efficient Multi-Core Chips
Modeling the Dynamics and the Gravitational-Wave Emission of Coalescing Compact Binary Systems. This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). The research spans several topics in gravitational
Modeling the Dynamics and the Gravitational-Wave Emission of Co-Alescing Compact Binary Systems
Investigation of nonlinear wave-particle interactions  The proposed project is aimed at studying the fundamental wave-particle interactions between energetic electrons and whistler-mode waves.  It consists of a theoretical/ modeling component,
This project will investigate the theory of kinetic Alfven waves along auroral field lines in the Earth's magnetosphere. Such waves play a major role in carrying energy from the outer magnetosphere to lower altitudes where it accelerates the pr
Theory of Kinetic Alfven Waves on Auroral Field Lines
Entanglement 'the bizarre' nonlocal connection that can exist between quantum systems is the critical resource in most quantum information processing (QIP) applications, and entangled photons are the central carriers of quantum information in m
Foundations and Applications of Hyperentanglement
Federal project 0904121, involving grading, draining, placing crushed base and bituminous pavement  surfacing and miscellaneous work on 6.99 miles of Interstate 90, beginning at reference marker  195.01, approximately 8 miles northeast of Sunda
Collaborative Proposal: Continuation of the XENON Dark Matter Project: Construction and Underground Operation of an Upgraded XENON100 Detector A continuation fund to support the operation of XENON100 dark matter detection project and to support
COLLABORATIVE PROPOSAL: CONTINUATION OF THE XENON DARK MATTER PROJECT: CONSTRUCTION AND UNDERGROUND OPERATION OF AN UPGRADED XENON100 DETECTOR
The project involves research on conditional moments of random fields, random matrices, noncommutative probability, and large deviations. The PI will explore connections between classical and free probability from several inter-related angles.
Research on Classical and Non-Commutative Probability
This project will develop an advanced 3-D hybrid simulation code (fluid electrons + kinetic ions) that included the coupling of the magnetosphere to the ionosphere. The hybrid magnetosphere model will be coupled an ionospheric model developed a
Collaborative Research: Enabling Breakthrough Kinetic Simulations of the Magnetosphere via Multi-zone Petascale Computing
Collaborative Research: Uncertainty quantification for petascale simulation of carbon sequestration through fast ultra-scalable stochastic finite element methods
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). The goals of this research project are to understand how variables within social computing environments improve older adult cognition, what proper
ARRA: HCC: MEDIUM: COLLABORATIVE RESEARCH: IMPROVING OLDER ADULT COGNITION: THE UNEXAMINED ROLE OF GAMES AND SOCIAL COMPUTING ENVIRONMENTS
Describing the action of the nervous system in quantitative terms is an important goal in neuroscience, but has been hampered by lack of appropriate techniques to describe the complex time-varying activity patterns of individual neurons. The ac
COLLABORATIVE RESEARCH:  A COMPREHENSIVE APPROACH TO BIRDSONG DYNAMICS:  EXPERIMENTS AND MODELING
'The investigators, with their students and postdocs, pursue an interdisciplinary project with three primary aims. The first aim is the development, optimization, and dissemination of novel computational methods based on arbitrary-order Hermit
Collaborative research: simulation and analysis of turbulent jet noise using arbitrary-order Hermite methods
BETH ISRAEL DEACONESS MEDICAL CENTER INC
Value Sensitive Design and Implantable Medical Devices Our group has continued to conduct extensive, semi-structured interviews to explore a value-sensitive analysis of technological advances in implantable medical devices.  The current series
TC: Medium: Collaborative Research: Mobile Personal Privacy and Security - A New Framework and Technology to Account for Human Values
ARRA: NETS: MEDIUM: COLLABORATIVE RESEARCH: TOWARDS VERSATILE AND PROGRAMMABLE MEASUREMENT ARCHITECTURE FOR FUTURE NETWORKS
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  Interoperability of heterogeneous data is a critical problem faced by every modern enterprise that is concerned with data analysis, data migratio
III: Medium: Data Interoperability via Schema Mappings
The investigator and his colleagues propose and study a model which can be used to characterize extremes (specifically threshold exceedances) on a regular spatial lattice. A spatial model for threshold exceedance data needs to handle situations
Models for Extremes on a Spatial Lattice
RI: MEDIUM: COLLABORATIVE RESEARCH: THE EFFECT OF SUBGLOTTAL RESONANCES ON MACHINE AND HUMAN SPEAKER NORMALIZATION
Parallel, distributed, and Internet-based computing, communication, and information systems are heterogeneous mixtures of machines and networks. They frequently experience degraded performance due to uncertainties, such as unexpected machine fa
CSR:Medium:Collaborative: Stochastically Robust Resource Allocation for Computing
'In this project the PIs will investigate human-robot interaction in situations where a human is highly dependent upon a robot that serves as the medium for the outside world, such as emergency response, hostage negotiation, and healthcare. In
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).'    There is a growing need for wireless networks that can sustain high data rates, are robust to interference, make efficient use of battery reso
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). The goal of this project is to develop computational models of the nonverbal behavior and interactive strategies observed during face-to-face teac
HCC: Medium: Collaborative Research: Computational Analysis of Nonverbal Behavior in Adaptive Tutoring
The principal investigator will probe the connection between Heegaard Floer homology and Khovanov homology, two theories, inspired by ideas in physics, that have transformed the landscape of low-dimensional topology during the past decade. The
Connections between Khovanov - and Heegaard Floer - type Homology Theories
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). The investigator will carry out several research projects studying various aspects of conformal geometry and asymptotically hyperbolic metrics. Th
Conformal Geometry and Asymptotically Hyperbolic Metrics
Visualization is one of the most important and commonly used methods of analyzing and interpreting digital assets. For many types of computational research, it is the only viable means of extracting information and developing understanding from
Enabling Transformational Science and Engineering Through Integrated Collaborative Visualization and Data Analysis for the National User Community
The research objectives of this project are first to prove the theoretical validity of the bootstrap method as a general inferential tool for the semiparametric models, and then invent a computationally attractive bootstrap inference procedure,
General Semiparametric Inference via Bootstrap Sampling
The goals of this research are to (1) develop new proton conducting materials for fuel cell applications and (2) understand fuel cell reaction pathways so as to ultimately eliminate precious metals from fuel cell designs. The significance of s
Next Generation Superprotonic Solid Acids
This research project aims to develop robust estimation methods for various non-and semiparametric frontier models using the efficient polynomial spline quantile smoothing method. More specifically, the objectives of the proposed research inclu
Robust Frontier and Boundary Estimation: Theory and Application
Native American Housing Block grant, Formula-new construction, rehabilitation including energy efficiency and conservation, and infrastructure development
Native American Housing Block Grant Formula - New construction, acquisition, rehabilitation including energy efficiency and conservation, and infrastructure development.
Indian Housing Block Block Grant. 1.Privately Owned Home Rehabilitation for Tribal Members. 2. Modernization of Low Income Apartment Housing Stock.
Native Averican Housing Block Grant, (Formula) Recovery Act Funded - Development/New Construction - ($108,783.00)  Develop two units by following necessary NAHASDA related requirements such as environmental, procurement, etc. (2 families  $108,
Native American Housing Block Grant,(Formula) Recovery Act Funded - Development/New Construction. Replace substandard units of existing homeowners with new units.
Native American Housing Block Grant Formula-New Construction , Acquisition, rehabilitation inlcuding energy effiiciency and conservation and infrastructure development.
Replacement of 2 homes for tribal members
Rehabilition of 17 existing Low Rent units and the Demolition and replacement of 3 existing modular Low Rent units.
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). The research objective of this award is to build tools for analysis and synthesis of nonlinear systems with particular emphasis on Atomic Force Mi
Less Conservative Criteria for Analysis and Synthesis of Nonlinear Systems
The earthquake induced ground motions are not the same at any two points on the earth’s surface. This occurs because the seismic waves travel from the earthquake source through different paths with different velocities, and reach the ground s
Spatial Variability Effects on the Seismic Response of RC Highway Bridges
This grant provides funds to explore new transportation security system paradigms that are proactive and meet the needs of our national transportation infrastructure. Methodologies from control theory and Markov decision process models and algo
New Approaches to Protecting Transportation Infrastructure
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).    This project aims to define and apply non-commutative analogues of the Heisenberg and Weil representations of the symplectic group acting on in
Heisenberg and Weil representations in noncommutative geometry
This project develops new methods for analysis and optimization of Markov Decision Processes with general state and action sets. In the case of continuous time Markov Decision Processes, this project also studies problems with unbounded transit
COLLABORATIVE RESEARCH: UNCOUNTABLE MARKOV DECISION PROCESSES AND THEIR APPLICATIONS TO OPTIMIZATION OF LARGE-SCALE STOCHASTIC SYSTEMS
This project is in the field of Commutative Algebra. The proposed research deals with the structure of graded free resolutions, their numerical invariants, and applications. The general research goal is to study graded free resolutions using a
Dr. Stella Offner is awarded an NSF Astronomy and Astrophysics Postdoctoral Fellowship to carry out a program of research and education at the Harvard-Smithsonian Center for Astrophysics. Dr. Offner will: (1) perform simulated observations of a
The Formation of Stars: From Clouds to Protostars- Institutional Allowance
The proposal addresses a variety of new problems that arise from a conjecture of S. B. Rao. Rao's conjecture itself concerns degree sequences of graphs, and remains open, although in joint work with Maria Chudnovsky, the PI has made substantial
Tournament Immersion and Rao's Conjecture
'The objective of this research is to develop a waveguide radio-frequency micro-electromechanical systems tunable filter as a unique three-dimensional microstructure in silicon. The approach is based on combining 1) bulk micromachining for mini
Miniaturized Waveguide RF MEMS Tunable Filters
The Principal Investigator plans to do research on the boundary between representation theory and number theory, exploring the implications of the local and global Langlands correspondence. He expects to extend his conjectures on restriction fr
Topics in representation theory and number theory
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  There are two parts to the research program in this proposal. Part one concerns multi-parameter Fourier analysis, the higher dimensional (or prod
Harmonic Analysis and the Theory of Elliptic Measure
The PI has studied how local properties affect the global parameters of various combinatorial structures. This is a very general framework of the so-called Turan number problems. The PI plans to continue his work on this topic and investigates
Extremal Hypergraphs, Codes, Designs and Combinatorial Geometry
The objective of this research is to acquire a better understanding of the charge transfer that takes place at the interfaces between organic semiconductors and metal, over a broad range of disorder in the organic material. This charge transfer
Exploring charge transfer at organic device interfaces
The proposed research aims to study several fundamental problems in extremal combinatorics, many of them motivated by problems in theoretical computer science. One area of investigations is the relation between local and global properties of gr
ARRA:  EXTERNAL PROBLEMS IN COMBINATORICS AND THEIR APPLICATIONS
Normal forms for intergrable PDE's and billards
The objective of this research is to demonstrate novel intrinsically switchable filters for frequency-agile communication systems and cognitive radios. The basis of the proposed effort is the investigation of field-tunable electrostriction effe
Novel RF/Microwave Switchable Filters Based on Electrostrictive Resonance in Ferroelectric Thin Films
The objective of this research is exploration of a growth and device processing technique to improve the energy efficiency and reduce the cost of light emitting diodes for solid state lighting. Key challenges to the widespread implementation of
Enhanced Vertical Transport III-Nitride Devices through Chemical Lift-Off Techniques
Objective The objective of this program is to provide new breakthroughs in the areas of stochastic control and global optimization through insights gained from particle filtering and from additional recent results in nonlinear filtering. With a
Particle Filtering for Stochastic Control and Global Optimization
'This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).'   Objective: The objective of the proposed research is to develop solid-state devices for achieving controlled and efficient coupling between si
This proposal requests partial support for research on Experimental Particle Physics at the CMS experiment at the LHC. The focus of the proposal is the upgrade of the Level 1 (L1) trigger of CMS by including information from the Pixel Detector.
Upgrade of CMS Level 1 trigger by addition of Pixel Detector data, and search for SM Higgs boson at CMS
FAMILY AND SOCIAL SERVICES ADMINISTRATION, INDIANA
Title: ARRA Supplemental Funding for the Child Care and Development Fund (CCDF); Description: Provide child care financial assistance to low-income working families and fund activities to improve the quality of child care.
HEALTH AND HUMAN SERVICES, NEW HAMPSHIRE DEPT OF
Community Services Block Grant Recovery funds will be used to carry out activities under sections 674 through 679 of the Community Services Block Grant Act.  NH Community Action Agencies will utilize funding for the following community and neig
Arctic soils have large stores of carbon (C) and may act as a significant CO2 source with warming. However, the key to understanding tundra soil processes is nitrogen (N), as both plant growth and decomposition are severely N limited. However,
Global warming is lengthening the growing season and increasing temperature in the arctic ecosystem. The lengthened growing season is featured by earlier snow melt and later fall freeze-up. Photosynthesis and respiration may respond differently
Effects of lengthening growing season and increasing temperature on soil carbon fluxes and stocks in Arctic tundra
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). It will provide funding for this group to continue their contributions to searching for the neutrinoless double beta decay. The observation of neu
Search for Neutrinoless Double Beta Decay with NEMO-3 and SuperNEMO Experiments
'GEM: Evolution of Plasmasphere, Plumes and Fine Structure.'   The cycle of erosion and recovery of Earth's plasmasphere evolves in distinct phases that depend on relative changes of the strength of magnetospheric convection as well as the elap
Does global warming increase the vigor of the hydrological cycle? This question forms the overall research theme of this study, which investigates the role of hydrological cycle feedbacks in climate change using a combination of proxy reconstru
Collaborative Research: Integrating Proxies and Earth System Models to Elucidate Water Cycle Dynamics: Did global warming cause an enhanced hyrdological cycle in the Eocene?
'GEM:  Why Does the Magnetosphere Enter a Steady Mode of Energy Transport Instead of an Oscillatory Mode?'  The goal of this project is to better understand the magnetospheric processes involved during steady magnetospheric convection (SMC).  T
Funding is provided to help characterize patterns of Holocene drought using new cave records from the Southwestern U.S. to better understand mechanisms of hydro-climatic variability in this arid region.  The research is centered on the followin
P2C2: Hydroclimatic Variability in the Southwest United States: New High-Resolution Speleothem Records of Past Drought
This project will combine data analysis and modeling to investigate: (1) phenomena that appear, or are significantly modified, only during the most extreme geospace disturbances, (2) the linkages between them, (3) the reasons they appear in som
This proposal requests funds to purchase equipment in support of seagoing research onboard Research Vessel WECOMA and other academic research vessels. This equipment joins a substantial existing inventory of shared-use equipment, and provides n
Quantum information storage and retrieval is becoming more significant and necessary in the current secure communications scenario due to its superior encryption techniques immunity to eavesdropping. There are many approaches to implement this
Maximum coherence in optical transitions in rare earth ion-activated solids
All animals rely on the integration of sensory, postural and environmental information to generate complex motor behaviors such as swimming, diving or flying. This collaborative project will study how the nervous system transforms information g
Collaborative Research: Integrated Analysis of In-Flight Collision Avoidance Systems
All animals rely on the integration of sensory, postural and environmental information to generate complex motor behaviors such as swimming, playing tennis or flying. This collaborative project will study how the nervous system transforms infor
The problem of providing seamless, integrated querying over multiple interrelated sources of information has been plaguing the database, information management, information retrieval, and artificial intelligence research communities for decades
III: Medium: Better Information Integration through Uncertainty
Proposal Title: RI: Medium Collaborative Research: Minimalist Mapping and Monitoring Institution: University of Illinois at Urbana-Champaign Abstract Date: 05/05/09 'This award is funded under the American Recovery and Reinvestment Act of 2009
RI: Medium: Collaborative Research: Minimalist Mapping and Monitoring
'A significant majority of current Internet traffic is due to distributing content, yet the Internet was designed to be largely agnostic to characteristics of the content flowing over it. This research investigates the design and operation of a
The purpose of this award is to support interdisciplinary research to develop high-performance computation codes and tools that enable multiscale computer simulations of cloud microphysics and cloud dynamics. The award supports collaborative re
COLLABORATIVE RESEARCH: PETAAPPS: ENABLING MULTISCALE MODELING OF TURBULENT CLOUDS ON PETASCALE COMPUTERS
Mean-field spin glass models and, in particular, the Sherrington-Kirkpatrick model were better understood in the past several years following the discovery of the replica symmetry breaking interpolation by Francesco Guerra and the proof of the
With the advent of new supercomputers that employ hundreds of thousands of processors and can compute at speeds approaching one quadrillion operations per second, many grand challenge science problems can be solved which were unsolvable even a
DEVELOPMENT OF EFFICIENT PETASCALE ALGORITHMS FOR INHOMOGENEOUSQUANTUM-MECHANICAL SYSTEMS
The objective of this research is to test Newton's inverse-square law of gravitation to 1% at a 100-micrometer range and to search for extra dimensions or other new physics down to a few tens of micrometers. This research will explore the very
Null Test of Newton's Law of Gravitation on a 100-Micrometer Scale
This project takes on two problems: (1) deciphering ancient texts using computers, and (2) training automated language translation systems without using parallel texts. Statistical language processing software has played little role to date in
RI: Medium: Deciphering Natural Language (DECIPHER)
Energy efficiency, the environment, and human health can be affected by combustion-generated soot, so controlling soot is a major technological and societal concern. This research is directed toward achieving soot prediction from turbulent comb
Collaborative Research: Petascale Computing, Visualization and Science Discovery of Turbulent Sooting Flames
The goal of this project is to take physics-based seismic hazard analysis (SHA) to a new level using petascale computational resources. Building on the scientific and technical successes under their current PetaApps award the PIs will incorpora
Outward on the Spiral: Petascale Inference in Earthquake System Science (SCEC PetaEye Project)
Collaborative Research: A Comprehensive Approach to Birdsong Dynamics: Experiments and Modeling
Title: HCC: Medium: Collaborative Research: Computer Vision and Online Communities: A Symbiosis. The project represents a new paradigm for research in computer vision related to content-based image management--one that exploits a symbiosis betw
HCC: Medium: Collaborative Research: Computer Vision and Online Communities: A Symbiosis
This award is funded under the American Recovery and Reinvestment Act of 2009(Public Law 111-5). This project will investigate people's social and moral relationships with personified robots. These robots, in various ways and to varying degrees
HCC: Medium: Social and Moral Relationships With Personified Robots
We plan to study the following three branches in the years to come. 1. Systematic study of stationary-harmonic multiple-valued functions; 2. Frequency and branch sets of multiple-valued functions; 3. Regularity of integral varifolds. These bran
Almgren's multiple-valued functions and geometric measure theory
A new era for particle physics is about to begin. The Tevatron and the LHC are soon going to start probing the scale where the mechanism of electroweak symmetry breaking has to show up. In the Standard Model this mechanism relies on the existen
New Electroweak Sectors in the Eve of the LHC
Successful completion of the effort of this proposal will make significant contributions to both theory and practice in multiagent systems, search, integer programming, planning under uncertainty, exchange design, electronic commerce, and trans
RI: Medium: Algorithms for Robust Barter Exchanges, with Application to Kidneys
It is widely recognized that current wireless spectrum policy has been an impediment to the continued growth of high-capacity wireless networks. This project is investigating the consequences of lifting current restrictions on spectrum allocati
NeTS: Medium: Design of Dynamic Spectrum Markets for Wireless Networks
III: Medium: Collaborative Research: Integration, Prediction, and Generation of Mixed Mode Information Using Graphical Models, with Applications to Protein-Protein Interactions
One of the main challenges in automatic speech recognition is variability in speaking style, including speaking rate changes and coarticulation. Models of the articulators (such as the lips and tongue) can succinctly represent much of this vari
(ARRA) Collaborative research:RI: Medium: Explicit articulatory models of spoken language, with application to automatic speech recognition
The proposed research seeks to formally and experimentally investigate defensive infrastructure addressing vulnerabilities in open cellular operating systems and telecommunications networks and other wireless networks.  This includes the develo
TC: Medium: Collaborative Research: Security Services in Open Telecommunications Networks
CSR:Medium:Collaborative Research: Stochastically Robust Resource Allocation for Computing
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  Traditional database systems are designed to provide the user with a clear picture of past states of the world as is represented in the database.
III: Medium: Longview: Querying the Future Now
Concurrency-related vulnerabilities are pervasive in modern computing systems. Concurrency exploits include time-of-check-to-time-of-use (TOCTTOU) race conditions in file systems, attacks on signal handlers, and evasive malware that uses concur
Intellectual merit.  The topics to be studied are in the interrelated areas of stahle and unstable homotopy theory, homotopical algebra, and higher category theory. Together, the work will expand our understanding of all of these areas. In stab
TOPICS IN ALGEBRAIC TOPOLOGY AND RELATED AREAS
This project supports the acquisition of a plasma-beam-forming instrument to study the first stages of the formation of organic molecules in gas-phase interactions. The instrument will simulate energy levels and densities in interstellar space,
Development of a Novel Instrument to Study the Cosmic Origins of Organic Chemistry and the Cosmo-Chemical Pathway towards Life
ID: MPS/DMR/BMAT(7623) 0906123 PI: Gopalan, Padma ORG: University of Wisconsin  Title: Surface Engineering Strategies for Studying Human Mesenchymal Stem Cells (hMSCs)  This award is funded under the American Recovery and Reinvestment Act of 20
ARRA Surface Engineering Strategies for Studying Human Mesenchymal Stem Cells (hMSCs).
This project will provide the necessary photo-excitation and emission data required to understand the important molecular physics and role in planetary atmospheres of molecular nitrogen (N2) by investigating the strong interactions among the Ry
EUV Photoexcitation and Emission of N2 at Low Temperatures
Recently derived connections between the intrinsic autoregressions and the de Wijs process open up the possibility to further explore and exploit connections between Gaussian Markov random fields and the continuum models in geostatistics to fac
CONNECTING MARKOV RANDOM FIELDS WITH GEOSTATISTICAL MODELS
This proposed research deals with methodological and inferential strategies in some non-standard problems that arise in certain non-parametric scenarios. The 'non-standard' problems include situations exhibiting non-standard asymptotics -- wher
Bootstrap and Threshold Models in Non-standard Problems
This award supports theoretical and computational research and education involving the magnetic properties of materials. Magnetism at the molecular scale is of fundamental importance in the development of future technologies. The goal of the pr
This research involves the design, synthesis, and study of network polymers containing highly selective, multiple hydrogen-bonding side-groups. The major research goal is to understand how reversible binding affects the materials rate-of-strain
POLYMER NETWORKS CONTAINING REVERSIBLY ASSOCIATING SIDE-GROUPS
'This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).'  Technical. This project addresses the epitaxial growth of high crystalline quality InGaN across the complete composition range. The aim is to g
Bridging the Miscibility Gap in InGaN Alloys
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). TECHNICAL SUMMARY: This award supports theoretical research and education focused on understanding fundamental aspects of quantum many-particle dy
Non-Equalibrium Dynamics in Closed Interacting Quantum Systems
In recent years, technological advances have dramatically increased the quality and quantity of data available to astronomers. Newly launched or soon-to-be launched space-based telescopes are tailored to data-collection challenges associated wi
Collaborative Research: New MCMC-enabled Bayesian Methods for Complex Data and Computer Models Applied in Astronomy
This project focuses on the physics of mesoscopic electronic devices. These devices are made of a large number of atoms, but are sufficiently small to exhibit quantum phenomena that are not found in macroscopic structures. Understanding how sma
Coherent Transport in the One-Dimensional limit
INTELLECTUAL MERIT: The overall aim of the proposal is to test the hypothesis that by mineralizing chitosan fibers, we can create a ceramic-based bone substitute material that combines the strength and stiffness of the ceramic phase with an inc
Mineralized Electrospun Chitosan Nanofibers as Bone Scaffolds MRI:  Development of Software Defined Communications Testbed for Radio and Optical Wireless Networking
This award supports theoretical and computational research that will develop new computational algorithms and tools for determining the relationship between the structure of a specific, possibly candidate, material and its properties. The PI w
The Generalized Cluster Expansion: A Tool for Representing Structure-Property Relationships
The objective of this project is to address and improve the poor constraints on gradients in chemical abundances across the galactic disk by carrying out a consistent, state-of-the-art analysis of a statistically-robust sample of several hundre
Metallicity Gradients in the Milky Way Disk
This work consists of three projects related to the computational analysis of dynamical systems with many degrees of freedom. The first concerns networks of coupled biological oscillators and excitable elements driven by fluctuating external st
Computational Analysis of Large Dynamical Systems
The investigator will utilize an integrated modeling approach to improve our understanding of Polar Mesosphere summer echoes (PMSE) from the cold summer Mesopause region, at altitudes between about 80-95 km at high polar latitudes.  The interes
EAGER: Exploration of the Source of Polar Mesospheric Summer Echoes at 33 cm Observed with the Poker Flat Incoherent Scatter Radar
Title: Research and Education in Physical Mathematics. This research focuses on the coupling of the analytical methods of applied mathematics to numerical computation, in the context of both research and education. It addresses a range of probl
Research and Education in Physical Mathematics
This ARRA award will fund research on multicore computing.  It is  primary output will be scientific publications, trained students, and  software to make application run better on multicore computers.    Multicore chips with hundreds of cores
CSR:Small: CoreTime:Dynamic Computation Migration for Multicore System Software
Research in communication networks has been driven by the need to reliably and efficiently reproduce information; not process it and make decisions. Information is transported without paying attention to its end use and decisions are arrived at
CIF:Small:Collaborative Research: Towards a Paradigm-shift in Distributed Information Processing: Harnessing Group-structure and Interaction
This project pursues a comprehensive research agenda in the design of topology control algorithms for reduced energy consumption, reduced interference and higher capacity in real wireless environments in the presence of multipath fading, link f
NeTS: Small: Collaborative Research: An Integrated  Environment-Independent Approach to Topology Control in Wireless Ad Hoc Networks
With a vision to fully realize the potential of next generation communication network infrastructure based on ubiquitous sensor nodes, this research introduces new architectures and strategies, for distributed in-network information processing,
CIF: Small: Collaborative Research: Towards a Paradigm-shift in Distributed Information Processing: Harnessing Group-structure and Interaction
The TEAMS project applies digital evolution to the design of robust communication services for cooperating groups of robots. Example applications include teams of robots for disaster relief operations, assisting humans in dangerous occupations,
CSR:Small: TEAMS -- Transplanting Artificial Life Behaviors to Mobile Robots
NeTS: Small: RUI:  Dynamic Indoor Location Computing and Benchmarking Project Summary The problems of indoor location computing are not yet fully solved. They still present many challenges and involve phenomena not yet fully understood, and the
NeTS: Small: RUI:  Dynamic Indoor Location Computing and Benchmarking
Computer processor industry has moved fully into the multi-core era to enable continual scaling of performance, but at the cost of increased energy consumption and increased cooling costs due to higher temperatures and thermal gradients. This p
SHF: Small: Reducing the Cost of Computation in CMPs
Securing cyberspace is one of the top priorities in protecting our national infrastructure. As wireless ad hoc networks (WANETs) have been built to access or been parts of the Internet, they become the weakest links which should be secured and
NeTS: Small:  How to Exploit Social Network Theory in Designing Secure Wireless Networks
Deployment is a fundamental issue in Wireless Sensor Networks (WSNs). In many missions today, sensors are deployed  deterministically in a planned manner. Instances include airport/harbor monitoring, intruder tracking on government property,  e
ARRA: NeTS: Small: Connected coverage of wireless sensor networks in theoretical and practical settings
This project architects high-performance wireless local area networks (WLANs) by understanding the impact of physical layer attributes on performance and incorporating them in the design and control of next generation WLANs. The research is com
NeTS:Small: Toward High-Performance WLANS: Bridging the Physical Layer Divide
Research is proposed to extend the scale and generality of separation logic and grainless semantics to become applicable to more complex and varied softward systems.  Specifically the following will be investigated:  Higer-Order Desgn Patterns,
SHF: Small: Specification, Verification, and Semantics of Higher-Order and Concurrent Software
Communication protocols on the Internet are typically designed first to work, then to interoperate and evolve, and eventually to be resilient to misbehavior and selfishness. Unfortunately, these extensions to protocols often sacrifice backward
Tremendous growth in hosted services and data sharing are motivating a new generation of storage virtualization technologies that encompass the entire data center or ensembles of data centers. Accurate dynamic resource provisioning is critical
CSR: Small: Workload Shaping for Capacity and Power Provisioning in Storage Data Centers
'This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).'  A Resource-Scalable Unifying Framework for Aural Signal Coding  The objective of this project is to achieve a comprehensive, unifying framework
CIF: Small: A Resource-Scalable Unifying Framework for Aural Signal Coding
Current stream engines are mostly stand-alone systems, whereas in many applications, stream processing will be one component of a larger information system. Coupling with other components, such as user interfaces, transactional data and archive
Towards More Flexible, Expressive and Robust Stream Systems
COLLABORATIVE RESEARCH: WHAT IS THE NENANA COMPLEX? NEW EXCAVATIONS AT THE LATE-PLEISTOCENE OWL RIDGE SITE, CENTRAL ALASKA
The Kalavasos and Maroni Built Environments Project is an interdisciplinary and collaborative effort by Cornell University and Ithaca College to investigate the relationships between architecture, social interaction and social change in Late Br
COLLABORATIVE RESEARCH: THE KALAVASOS AND MARONI BUILT ENVIRONMENTS PROJECT. INVESTIGATING SOCIAL TRANSFORMATION IN LATE BRONZE AGE CYPRUS
Senescence, the last developmental phase of annual plants including the world's most important food crops, is characterized by the massive remobilization of nutrients to the developing seeds. Knowledge gained from this project will be applicabl
Characterization of a regulatory pathway controlling cereal leaf senescence
Accurate predictions of community and ecosystem responses to climate change will require identifying not only the direct effects of altered climate on species, but also the indirect effects that occur through biotic interactions or as a result
COLLABORATIVE RESEARCH: Can microbial symbiosis mediate effects of climate change on the functioning of an ecosystem engineer?
The proposal requests numerous Shipboard Scientific Support (SSSE) items for the R/V MARCUS LANGSETH namely; a new magnetometer winch, new stern capstans, a new X-band RADAR, and installation costs for the Fleet Broadband satellite communicatio
Natural history museums are irreplaceable sources of species data and they are often the only source of historical data. Yet, many are poorly supported, putting their contents in jeopardy of decay or abandonment. This project uses mathematical
Using Museum Records and Distribution Models to Reconstruct the Historical Assemblage for Midewst Plecoptera
The Montana-Kentucky (MTKY) cyber consortium is a partnership of the primary research universities in the two states--University of Kentucky (UK), University of Louisville (UL), Eastern Kentucky University (EKU),University of Montana (UM), Mont
Collaborative Research:  Cyberinfrastructure for a Virtual Observatory and Ecological Informatics System (VOEIS)
This project investigates exceptionally species-rich but poorly known fossil plant deposits in Patagonia, Argentina, dating from 66-47 million years old. Approximately 80% of more than 500 species so far collected are new to science, and the ti
COLLABORATIVE RESEARCH: ANCIENT BIODIVERSITY HOTSPOT IN SOUTHERN SOUTH AMERICA: EVOLUTION OF SPECIOSE FLORAS IN PATAGONIA FROM LATEST CRETACEOUS TO MIDDLE EOCENE
Project Description   Two important aims of comparative biology are to identify characteristics that affect the rates at which new species form or become extinct, and those that evolve more frequently in one direction than another. This project
The History and Consequences of Self Incompatibility
The Arctic has been experiencing great warming and ecological changes in recent decades. The last pronounced warm period occurred about 11,000-9,000 years ago in Alaska. The warm and possibly dry climate resulted in unusual ecosystem types and
Collaborative Research: Impact of Climate Seasonality on Carbon Accumulation and methane Emissions of Alaskan Ecosystems during the Holocene Thermal Maximum
Flowering plants (angiosperms) are the most diverse group of plants on Earth (>280,000 species) and comprise almost all of our agricultural crops, yet little is known about the interplay of biological and environmental factors that have fostere
The hippocampal formation (hippocampus and entorhinal cortex) is essential for making episodic memories in the mammalian brain. The physical substrate of memory resides in the connections among groups of cells (ensembles) and their dynamic acti
Theta and Gamma Coherence: Entorhinal Cortical Influences on the Septotemporal Axis of  the Hippocampus
Moderate temperature variations have large effects on various plant processes including defense responses. Often, an elevated growth temperature above the norm renders an otherwise resistant plant susceptible to pathogens. This project aims at
MOLECULAR MECHANISMS UNDERLYING TEMPERATURE MODULATION OF DEFENSE RESPONSES
This award funded by the Recovery Act has allowed ASI Federal Credit Union, a CDFI serving over 80,000 members in the New Orleans Metro Area, to use proceeds to augment the institution's loan loss reserve.  Increasing reserves allows us to incr
Community Development Financial Institutions Fund 2009 Award - Loan Loss Reserve
Financial Assistance Component under the CDFI Program; Low Income Investment Fund's use of the ARRA Award from the CDFI Fund was to add equity and/or leverage Low Income Investment Fund's operating fund/capital, enabling Low Income Investment F
Financial Assistance Component, CDFI Program
Award will be used to provide loans necessary to create affordable housing for households making less than 60% area median income in the state of Kansas.
Recovery Act funds were deposited in MCDCs loan fund and used to lend to borrowers for business loans and microloans.  Recovery Act funds also are being used to leverage  philanthropy donations and other sources of funding.  Recovery Act fundin
The Recovery Act award was used to assist First Legacy Community Credit Union?s low to moderate income members in keeping their homes and maintaining their employment by having safe and reliable transportation through the credit union?s home an
Credit Union Foreclosure &  Auto Lending
The financial assistance award will be used to make loans and equity investments in qualified businesses in our four state service area.
Many animals communicate with members of their own species using specific sounds. These sounds are behaviorally relevant to the animals because they facilitate important behaviors such as maintaining a territory or finding offspring on return f
RUI:  Neural Encoding of Behaviorally Relevant Sounds
A major issue in understanding how evolution has shaped social communication is determining how the brains and behavior of communication signal sender and receiver are matched so that signals such as vocalizations convey meaningful social infor
Co-Evolution of auditory coding and vocal behavior
Understanding how animals adapt to environmental changes is an important question, and has implications for many fields. Little is known about early life stages, especially their ability to deal with different environments. Aquatic invertebrate
Collaborative Research: Phenotypic Plasticity in Feeding: Ontogenetic Solutions to Scaling Limitations
Microorganisms are the oldest living inhabitants of planet Earth, spanning some 3.5 billion years, and their importance in shaping the Earth?s soils, oceans, and atmosphere has long been accepted. The biosynthesis of magnetite (Fe3O4) by magnet
(ARRA) Collaborative research:  Using single-molecule force and fluorescence microscopy to elucidate the molecular mechanism of bioinspired magnetite synthesis in magnetotactic bacteria
Biologically active suspensions, of which a bath of swimming bacteria is a paradigmatic example, are fluid systems whose microstructure is alive and motile. As the system's 'active particles' propel themselves through the surrounding fluid, the
Collaborative Research: The Analysis and Simulation of Biologically Active Suspensions
There are relatively few records that reflect large-scale changes in atmospheric circulation during the last glacial-interglacial cycle, and very few with sufficient temporal resolution and/or continuity to resolve the timing and sequence of ch
High-resolution records of atmospheric circulation and past rainfall from soils based on U-series and stable isotope SIMS approaches
The chloridoid grasses are a large, economically and ecologically important group of approximately 1500 species in 150 genera that have been classified using the highly variable features of the inflorescence (how flowers are arranged). Despite
Collaborative research: Branching in chloridoid grasses: phylogeny and inflorescence diversification
The major goal of this research is to understand the molecular genetic basis of adaptation to seasonality in the model organism Drosophila melanogaster. Although this species is native to sub-Saharan Africa, a form of reproductive diapause (ana
COLLABORATIVE RESEARCH: Evolutionary dynamics of a molecular polymorphism for diapause and life histories in Drosophila melanogaster
The research will investigate the ways in which claims to sovereignty in the Arctic rely on territorial imaginaries; explicit and assumed of a place's elemental nature, its geophysical properties, and its geographic location.  How do they inter
Collaborative Research:  Territorial Imaginaries and Arctic Sovereignty Claims
Collaborative Research: Backdating the U.S. Supreme Court Judicial Database, 1793-1946
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). This project investigates the activities and experiences of African Americans in local civil courts from the Civil War through the Great Migration
Surveys represent a key source of data in a wide range of scientific disciplines, and are often an important input in public and corporate decision-making processes. While the primary use of survey data is to describe the population from which
Some Issues in Analytic Inference from Complex Surveys
'Most of the rivers in hilly and mountainous landscapes have small, steep channels, which are typically mantled by boulders that rarely move. In these channels, boulders moderate the rate of river incision, roughen the flow creating local patc
When do boulders move in steep mountain streams?
Nitrogen is an essential element for life on Earth, yet fixed nitrogen is relatively scarce in the oceans. Simultaneously, global nitrogen budgets are difficult to balance, suggesting unknown nitrification and denitrification reactions may acco
ARRA: THE ROLE OF ANAEROBIC MANGANESE RESPIRATION IN CYCLING OF NITROGEN IN SEDIMENTS
This project would contribute to the literature on identification and inference in incomplete econometric models. An econometric model may be incomplete when, for example, sample realizations are not fully observable, or when the model asserts
COLLABORATIVE RESEARCH: IDENTIFICATION IN INCOMPLETE ECONOMETRIC MODELS USING RANDOM SET THEORY
Many pay-as-you-go social security systems in the United States and Europe face impeding insolvency as the number of pensioners per worker rises. Among the possible reforms being considered is transiting to fully funded privatized accounts syst
Regulating the Selection of Products under Investment Accounts Pension System: A Study of the Chilean Experience
MRI-Consortium: Development of a Neutron Detector Array by Undergraduate Research Students for Studies of Exotic Nuclei.
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  Exposure to stress early in life can have profound effects on physiology and behavior later in life, which may alter the ability of individuals t
The neuroendocrine stress axis in amphibian development and physiology
As the ubiquity of wireless networking leads to an increasing reliance on high-speed data communications, there is clearly an impending need for new high-bandwidth, inexpensive, flexible, and upgradable wireless communications technologies to m
MRI:  Development of Software Defined Communications Testbed for Radio and Optical Wireless Networking
Award title: Analysis of the Cell Biological Mechanisms of Learning and Memory in the Zebrafish.  Award description: The purpose of the proposed project will be to develop the zebrafish (Danio rerio) into a useful model system for cellular and
NEUROBIOLOGY OF SIMPLE FORMS OF LEARNING IN THE ZEBRAFISH
With this award from the Major Research Instrumentation (MRI) program, the Chemistry Department at Northwestern University will acquire a gas chromatograph time-of-flight (GC-TOF) mass spectrometer for use in teaching and research. A variety of
MRI: Acquisition of a Time-of-Flight GC-Mass Spectrometer
This project from North Dakota State University aims for acquisition of a remotely operable analytical field-emission scanning electron microscope (FE-SEM) with energy-dispersive X-ray spectrometry, along with specimen preparation equipment. Th
MRI: Acquisition of an Analytical Field-Emission Scanning Electron Microscope (SEM) for Multipurpose Imaging, microanalysis, and education
Camp), the NSF STEP funded UCORE summer internship program for undergraduates from community colleges, and advanced instrumentation workshops for faculty, students, and industrial collaborators. Examples of programs that extend the impact of t
MRI: Acquisition of a Dual Beam Focused Ion Beam Instrument for Materials Characterization, Nanoarchitectures, and Physics of Nanodevices.
High-resolution geochronology is instrumental in providing evidence for a causal link between continental-scale, short-term volcanic events and environmental crises. We seek support for a three year collaborative research proposal aimed at unra
COLLABORATIVE RESEARCH: The end Guadalupian (ca 260 Ma) biotic crisis: Research into timing, potential causes, and environmental proxies
Intellectual merit. One of the many inhabitants in the leafy debris of the forest floors is social amoeba. These are ancient organisms that diverged and evolved independently from mammals quite early in evolution. Social amoeba are quite remark
Regulation of Talin Function in Amoeboid Cells
IRMS currently in the facility is a 20 year old Delta E which cannot be fitted for continuous flow operation. The proposal seeks a Thermo Delta V Plus IRMS configured for continuous flow with various introduction interfaces (EA, TCEA, GasBench
MRI:  ACQUISITION OF LIGHT STABLE ISOTOPE MASS SPECTROMETER FOR RESEARCH AND TEACHING IN GEOCHEMISTRY, PALEOBIOLOGY, AND COSMOCHEMISTRY
The overall objective of this project is to commercialize targeted in vivo delivery agent kits and reagents such that they are readily available to researchers to perform directed RNAi in vivo experiments. Currently, access to this technology i
Improved targeted in vivo delivery of siRNA
This Small Business Innovation Research (SBIR) Phase II project aims to commercialize and expand the application of piezopolymer nanocomposite technology. Piezoelectric materials are an alternative energy source, which interconvert mechanical a
SBIR Phase II:Disruptive Performance From Engineered Piezoelectric Organic Polymer Nanocomposites: Inventive Approach To New Electrical and Mechanical Energy Conversion Materials
Plastics Material and Resin Manufacturing
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  This Small Business Innovation Research (SBIR) Phase II project will combine lighter weight and quiet piezoelectric technology into an innovative
SBIR Phase II: A Multi-Grip Prosthetic Hand
This project will determine how dopamine (DA) modulates motor control in the European medicinal leech and how DA affects the decision whether the animal will crawl or swim. The contribution of the Kristan laboratory will be to identify neurons
Collaborative Research: The neurobiology of dopamine in the leech and the modulation of locomotor behaviors
Social scientists recently exposed the myth of universal water services coverage in the United States: migrant farm workers, the rural poor, and urban homeless communities face substantial deficiencies in water and sanitation infrastructure. Al
HOUSEHOLD WATER SECURITY IN LOW-INCOME RURAL AND PERI-URBAN COMMUNITIES IN SOUTH TEXAS
This award funds research to conduct laboratory experiments that will compare the outcomes of different auction mechansims. One of the most fruitful areas of theoretical auction research has been the comparison of static auction mechanisms with
Common-Value Auctions with Liquidity Needs
Routines are vital to how work gets done in organizations. Routines are repetitive, recognizable patterns of interdependent actions carried out by multiple actors. These patterns can be flexible or rigid; they can produce efficiency gains or pe
Formation and Dynamics of Organizational Routines
This project is an investigation of Polar Mesospheric Clouds (PMCs) that uses both satellite observations and model simulations to determine the cloud occurrence frequency, variation with latitude and longitude, and the possible response to the
CEDAR Postdoc: Polar Mesospheric Cloud Structures as Evidence of Coupling Between the Upper and Lower Atmosphere
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  This award funds the development of new software for conducting economic experiments at the LEEPS lab of the University of California at Santa Cr
The project focuses on the development of a new tool for solving pattern recognition problems.  This tool is based on the application of an original artificial neural network & multilayer nueral network with multi-valued neurons.  This network
RUI: Multilayer Neural Network with Multi-Valued Neurons, its Application to Image Recognition and Processing and Incorporation of the Research into the Educational Process
There is tremendous current interest in molecular machines: nanoscale systems that carry out specific tasks of mechanical work, microscopic assembly, or information processing. Alongside rapid progress revealing the details of biological molecu
Collaborative Research: Designing Non-Autonomous Molecular Machines
The objective of this research is to realize efficient infrared electroluminescence using a hybrid organic-inorganic light-emitting device based on emissive group IV semiconductor nanoparticles including Si, Ge and Si1-xGex.  Intellectual Merit
Hybrid Organic-Inorganic Infrared Light-Emitting Devices using Group IV Semiconductor Nanoparticles
An international collaboration project ?Future Oxides and Channel materials for Ultimate Scaling (FOCUS)? between US, Ireland and Northern Ireland investigators is established. The project will investigate the chemical, structural, and electric
US-Ireland collaborative research on Future Oxides and Channel materials for Ultimate Scaling (FOCUS)
Natural disturbances such as fires and pests are the primary factors influencing landscape patterns and processes over broad parts of the Earth. In the montane forests of the North American west, insect outbreaks and fire constitute the dominan
Collaborative Research:  A Pilot Study of the Spatiotemporal Scales of Diversification in the Pandora Moth/Ponderosa Pine System Using Dendrochronology and Evolutionary Biogeography
This project proposes to investigate and implement a variety of tools for enhancing the very widely used and popular Arxiv.org infrastructure, based on information filters for assisted service discovery and selection, text-mining, information g
TOOLS FOR OPEN ACCESS CYBERINFRASTRUCTURE
Modern networks (like InfiniBand and 10GigE) have capability to provide topology, routing and also network status information at run-time. This leads to the following broad challenge: Can the next generation petascale systems provide topology-a
ARRA: Topology-aware MPI collectives and scheduling for petascale systems with infiniband
The research objective of this award is to develop a science-based design methodology that can be extended to create materials undergoing stress-induced phase transformation with superior properties. The work proposes to advance knowledge in de
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). The objective of this project is to develop a theoretical framework for monolayer graphene based on nonlinear continuum mechanics and atomistic mo
Nonlinear Mechanics of Graphene-Based Materials
'This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).'  Although the various pathways of nitrogen exchange at the sediment-water interface are critical to our understanding of ecosystem functions, ex
Collaborative Research: Using Biogeochemical and Genetic Tools to Unravel the Environmental Controls of Nitrogen Fixation and Denitrification in Heterotrophic Marine Sediments
'The recently released Uniform California Earthquake Rupture Forecast by the Working Group on California Earthquake Probabilities concludes that there is a high probability that an earthquake of magnitude 6 or larger will occur on the southern
Quantifying the Risk Posed to Tall Steel Frame Buildings in Southern California from Earthquakes on the San Andreas Fault
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  Overfishing is emerging as one of the greatest threats to the integrity of marine ecosystems and the societal services they provide. Though the c
Is overfishing triggerng the die-off of New England salt marshes?
Natural Resources Conservation & Protection
Designing materials with cues to induce or enhance adult stem cell differentiation into cartilage cells would improve treatment options for patients suffering from osteoarthritis, a degenerative disease that affects articular cartilage. Healthy
Bridge: Peptide-based Cues for Mesenchymal Stem cell Differentiation in Cartilage Graft Applications
Permeable granular piles (ie., sand compaction piles, stone columns, and rammed aggregate piers) are commonly used to support structures and highway facilities constructed on soft or loose soils subjected to static and seismic loading. Although
RUI: Pervious Concrete Piles:  An Innovative Ground Improvement Alternative
This project is an effort to study the spatial/temporal variability of methyl bromide and other halocarbons in the upper ocean in response to the implementation of the Montreal Protocol and its amendments.  The long-term goals of this work are
Methyl Bromide and Selected Halocarbons: Response of the Ocean to the Montreal Protocol and Subsequent Amendments
GEOTRACES is a newly initiated international oceanographic program to identify processes and quantify fluxes that control the distributions of key trace elements and isotopes in the oceans and to establish an understanding of the sensitivity of
Manganese, vanadium, gallium and rare earth elements in the GEOTRACES North Atlantic zonal section
The role of iron as a limiting nutrient in many oceanic regions has been established, and atmospheric deposition has been recognized as a major source of iron in the global ocean. The fraction of iron that dissolves in seawater after its atmosp
U.S. GEOTRACES North Atlantic Sector: The Fractional Solubility of Aerosol Iron in Seawater
The research objective of this Grant Opportunity for Academic Liaison with Industry (GOALI) Collaborative Research award is to develop capabilities for engineering surfaces with specific micro-scale and ultrafine grained structures, and enhan
GOALI: Collaborative Research: Engineered Surface Microstructures by Machining
UNIVERSITY OF MARYLAND CENTER FOR ENVIRONMENTAL SCIENCE
Researchers at the University of Maryland will conduct a laboratory study of carbonate co-precipitation and phosphate complexation of yttrium and the rare earth elements (YREEs). These processes are anticipated to be sensitive to minor pH varia
Investigating YREE Co-Precipitation with Phosphate and Biogenic Aragonite as Possible Indicators of Ocean Acidification
The objectives of the GEOTRACES program are: 1) to determine the global distributions of selected trace elements and isotopes and evaluate the sources, sinks and internal cycling of these species to better understand the physical, chemical and
U.S. GEOTRACES North Atlantic Section: CFC and SF6 Measurements
Objectives and Methods to be Employed-Chemical processing frequently requires vaporizing liquid reagents, mixing, and heterogeneous reaction in the presence of a solid catalyst, followed by product separation. In traditional large scale chemica
ARRA: LIQUID FUEL REFORMATION IN DIRECT DROPLET IMPINGEMENT MICRO REACTORS
Focus on Mathematics (FoM) has, since 2003, been a project of NSF's Math and Science Partnership program that engaged Boston University, the Education Development Center, Inc., the University of Massachusetts at Lowell, and an array of Massachu
Focus on Mathematics, Phase II: Learning Cultures for High Student Achievement
This grant provides funding for developing experimental design theories and techniques for product and process reliability responses that will fill the gap that currently exists in design for reliability. Direct application of traditional desig
Collaborative Research: Efficient Experimentation for Product and Process Reliability Improvement
The research objective of this award is to develop a universal manufacturing method to fabricate composite functional structures/materials on three dimensional surfaces using laser dynamic forming. This research will enable an innovative and po
IDR/Collaborative Research: Manufacturing Functiolnal Laminated Composites Structures on Patterned Uneven Three-Dimensional Surface
To support the preservation of jobs that are threatened by declines in philantropic and other support during the current economic downturn.
HAWAII STATE FOUNDATION ON CULTURE AND THE ARTS
To support the preservation of jobs thta are threatened by declines in philanthropic and other support during the current economic downturn.
COMMISSION ON CULTURE AND TOURISM OF THE STATE OF CONNECTICU
Art and the American Recovery & Reinvestment Act
STATE PARKS AND CULTURAL RESOURCES, WYOMING DEPT OF
GUAM COUNCIL ON THE ARTS AND HUMANITIES AGENCY
To support the preservation of jobs that are threatened by declines in philanthropic and other support during the current economic crisis
Arts & American Recovery & Reinvestment Act
EDUCATION & EARLY DEVELOPMENT, ALASKA DEPARTMENT OF
CNMI DEPARTMENT OF COMMUNITY AND CULTURAL AFFAIRS (DCCA)
To support the preservation of jobs that are threathened by declines in philanthropic and other support during the current economic downturn.
Award is to support the preservation of arts sector jobs that are threatened by declines in philanthropic and other support during the current economic downturn.
Wax esters are a highly valued class of lipid utilized in cosmetics, pharmaceuticals, as fine lubricants, and as fuels. The study of the pathways utilized by different organisms to produce and accumulate energy storage compounds such as lipids
Bacterial Enzyme Systems for Wax Ester Production
HEALTH & FAMILY SERVICES, KENTUCKY CABINET FOR
ARRA provides funding for Home-Delivered Nutrition services. Established in 1978 under the Older Americans Act, the program provides meals to seniors who are homebound.
AGING & LONG-TERM SERVICES DEPARTMENT, NEW MEXICO
2009 T3C2_ARRA - ARRA provided funding for Home Delivered Nutrition Services.
ARRA funding of home delivered nutrition services will augment existing resources, replace revenue lost from local resources due to the economic downturn and support the continued delivery of meals to vulnerable older Americans.  Home delivered
ARRA provided funding for Home Delivered Nutrition Services.  Established in 1978 under the Older Americans Act, the program provides meals to the home bound.
AGING & DISABILITY, TENNESSEE COMMISSION ON
Dept Id. 3460020000 / Program code 43892
Native American Housing Block Grant, Competitive
Gathering Place Infrastructure & Rental Housing Unit Construction Project
The Pleasant Point Passamaquoddy Tribe is charged with providing safe, decent, sanitary and affordable hoursing for its tribal members.  The project will help alleviate the great demand for affordable housing by providing nine larger family-siz
Native American Housing Block Grant Competitive-American Recovery and Reinvestment Act of 2009
The award dollars will be used for modernization and rehabilitation of low income rental units which will bolster energy effiecency.  The end result will be a reduction in the high heating costs being experienced by low-income families.
Grand Portage Low Income Rental/Home Buyer Project
NAHBG, Competitive-NAHASDA-Eligible activities including, Acquisition, New construction, Rehabilitation of affordable housing, site improvement, development and rehabilitation of utilities and infrastructure, utilities services, conversion, dem
NORTHERN CHEYENNE TRIBAL HOUSING AUTHORITY
The Housing Authority shall provide modernization activities on up to 75 identified existing mutual help units.
Construction of twenty (20) Lava Block homes. Project completed.
With this grant we plan to develop some existing property we own by constructing 6 single family units which includes 1 handicap accessible unit. These homes will be used in our Low Rent program.  We were in need of more 3 bedroom homes as oppo
Native American Housing Block Grant Program Recovery Act
Natvie American Block Grant Recovery Act will be used for infrastructure for Econtuchka Estates and Rolling Meadows phase 2 (25 house pads at Rolling Meadows Ph 2)
Native American Housing Block Program - Recovery Act (Competitive): Low Income Housing Activities
Housing Rehabilitation and Multifamily New Construction
Native American Housing Block Grant, Competitive - construction 9 single family homewnership units for low income Indian families
Construct two (2) 'Green' multi-family units at the Murray Road Housing Development.  The two (2) units will accommodate nine (9) housholds.  The design and construction activities shall utilize Energy Star appliances and 'Green' development.
Native American Housing Block Grant (Competitive) Recovery Act Funded
The ARRA funds are being used to help us increase our housing by allowing us to build more rental homes.
Native American Housing Block Grant (Competitive) NAHASDA
Native American Housing Block Grant, Competitive - NAHASDA-eligible activities incluidng acquisition, new construction, rehabilitaiton of affordable housing, site improvement, development and rehabilitation of utilities and infrastucture, utili
Mold assessment and remediation plans for 145 units. Implement remediation plans to remove mold from 100 homes.  Install new steel roofs on 100 homes. Provide insulation during reroofing for 124 homes. Modified objective: add 24 homes for a tot
NATURAL RESOURCES & CONSERVATION, MONTANA DEPT OF
Project consists of four subprograms: Lake County Forest Stewardship ($426,500), Swan Valley Stewardship ($426,500), Lake County Hazardous Fuels ($84,000), & Flathead County Hazardous Fuels ($50,000).  All awarded grants will follow DNRC approv
Lake County Fuels Reduction & Ecosystem Restoration
This project will provide forest restoration and wildfire fuels hazard reduction treatments to forested state (DNRC, Montana Correctional Enterprises, Fish Wildlife and Parks, etc.) and non-industrial private lands (NIPF) primarily within the i
Montana Hazardous Fuels Reduction / Restoration Forestry Projects
The project will support multi-county/agency efforts of a coordinated invasive hawkweeds and rush skeletonweed programs.  It will also provide a fuels reduction/restoration program, supplement an existing integrated weed management program with
Managing Noxious Weeds & Invasive Species - Lincoln County, #WFM-0156-12HFE
The Northwest Montana Forest Pest Management grant funds ($296,000) will provide funding for forest health restoration activities in Flathead, Lincoln, Lake and Sanders Counties.  Project funds will be spread between state and non-industrial pr
Northwest Montana Forest Pest Management
Oregon Department of Forestry (ODF) will provide technical and financial support to landowners for active forest management to include: fire risk reduction, forest health and ecosystem improvement, use of woody waste materials for biomass energ
Incresed control of invasive species in MS.  Invasive species include, but not limited to cogon grass, Japanese privet, kudzu, Japanese climbing fern, etc.  There will be an Invasive Species Coordinator and he will have 2 assistants.  They will
Increased control of invasive species in MS
Co-firing  Forest Woody Biomass with Coal to Generate Electric Energy
Funding was awarded to assist Boulder County with enhancing a woody biomass utilization project that has two components. The first component includes enhancement of operations for currently existing as well as future proposed sort yards to util
This project utilizes ARRA funds to create the Ohio Woodlands Job Corps (OWJC), a program designed to provide temporary employment, job training and skill development that employees can use to further their careers in conservation management. T
This award will address two areas of Massachusetts in need of Native Species Ecological Restoration. The first is the detection, and identification of the Asian Longhorned beetle (ALB) in the area surrounding Worcester, MA where the beetles hav
USFS Native Species Ecological Restoration
Begin 4 lane E of Wadena to Staples (EB and WB) includes rumble strips from E of Staples to W of Motley
Concrete Pavement Rehab and Diamond Grind from Stearns CSAH 75 to 1.5 Mi W of Jct TH 23 and from Stearns/Wright Co Line to TH 25 in Monticello and Striping from Stearns CSAH 75 to Wright/Hennepin County Line
Bridge 9176 (local street flyover 90) in Austin
Overlay Parking Lot and Rehab Curb/Walk (ADA) at 2 Rest Areas, Clear Lake and Des Moines Rest Area
Replace Ex BR7251 with Triple Box Culvert, Bituminous Surfacing
On CSAH 6 from S Co Line to TH 14 3 Mi W and 6 Mi S of Tyler, CSAH 9 from CSAH 1 to CSAH 2, W of Verdi & CSAH 11 from CSAH 8 to E County Line
7th Avenue SE From 17th St SE to 33rd St SE Reconstruction
CSAH 29 to CSAH 32 in Beltrami County, Resurfacing
Replace Br 7130 over St. Francis River 0.25 Mi S of Sherburne CSAH 3 Jct and Approach Grading and Paving
Grading, Base, Bit, Curb and Gutter, Drainage, Signing and Stripping and Appurtenant Work from CR 120 to CR 134
Rebuild lighting system I 494 to Vernon Ave in Edina
EB and WB I494 Ramps to SB I 35E in the City of Eagan-Interchange Modification Separate Ramps
From 0.2 Mi N of TH 97 in New Scandia Twp. to 0.7 Mi S of Nelson St. in Stillwater Bituminous Mill and Overlay
From Jct I 494 in Maple Grove to Hennepin CSAH 152 (Brooklyn Blvd) in Brooklyn Park-Landscaping
NATURAL RESOURCES, WASHINGTON STATE DEPARTMENT OF
Accumulated fuel on millions of acres of forest land in the western United States heightens the risk of uncharacteristically severe wildfire. In recent years, the size and number of large wildfires has grown, threatening lives, property, nation
ARRA - Prioritize Fuel Treatments by Estimating Restoration Potential and Understanding Their Effects
The purpose of this agreement is to document the cooperation between the parties to develop and apply state and transition models for the four state area, and connect these models to methods that allow estimating the interactions of management
Prioritize Fuel Treatments by Estimating Restoration Potential and Understanding their Effects - Project Coordination Functions
Project Title: Carson-Iceberg and Hoover Wilderness Stewardship, Bridgeport and Carson Ranger Districts, Humboldt-Toiyabe National Forest  The Humboldt-Toiyabe National Forest, Bridgeport and Carson Ranger Districts, manage the Hoover and Carso
Carson-Iceberg and Hoover Wilderness Stewardship, Bridgeport and Carson Ranger Districts, Humboldt-Toiyabe National Forest
NYC programs use an outdoor lifestyle and challenging projects to teach problem solving and positive living skills, promote A strong and productive work ethic, encourage learning, and build self-esteem.   Youth in the program learn essential jo
Siuslaw National Fores t- Central Coast/ODNRA Ranger District - Snowy Plover Habitat Restoration
To accomplish non-native invasive plant control along the Cheoah River within the Cheoah Ranger District in Nantahala National Forest. Eight Species of non-native plants have been identified along the river between Santeetlah Dam and Lake Cheoa
WNC Alliance Cheoah River Non-Native Invasive Plant Control
Corporation for National and Community Service
AmeriCorps programs were awarded Recovery funds to expand the number of Members currently serving to address areas of need made more critical by a struggling economy.
AmeriCorps members focus on tutoring and literacy activities.
MISSISSIPPI COMMISSION FOR VOLUNTEER SERVICE
DIGITAL OPPORTUNITY TRUST (DOT):  ARRA funds enable 20 AmeriCorps members to be placed in classrooms to coach more than 350 teachers in effective techniques of integrating technology into all subject matters to engage 15,000 students in a learn
Award focuses on tutoring and literacy services for grades K-12; housing weatherization; financial literacy; health care insurance, access and benefits information distribution; and recruiting volunteers to address needs in their communities.
WI National and Community Service Board - Recov Competitive
GOVERNOR'S OFFICE ON NATIONAL AND COMMUNITY SERVICES
The AmeriCorps State Recovery awards were made available to exisiting AmeriCorps State grantees in Alabama for project expansion for up to one year. Three (3) sub-grantees expanded utilizing these funds. Expansion included increased support to
AmeriCorps members will provide employment training and skill counseling. Also, AmeriCorps members will provide tutoring and literary services to at risk students.  In addition,  AmeriCorps members will facilitate financial literacy planning se
Philanthropy, Charity & Voluntarism Promotion
AmeriCorps members will provide services to meet needs in Michigan communities in the areas of education, affordable housing, mentoring, youth and family services, and community renewal. This report represents completion of ARRA funded Michigan
Recovery Formula - Michigan Community Service Commission
Formula ARRA match replacement funds enable four subgrantees to continue providing services in their respective communities.  St. Rose AmeriCorps members have been trained in construction skills and in addition to recruiting and managing volunt
To be used on New Housing Construction of a combination of 14 units and Preservation (rehab) of our existing Formula Current Assisted Stock of 32 single-family units
Red Cliff Phase 2 & 3 Construction / Rehab
NAHBG - Competitive Grant for the construction of Ben Gay Heights, a 12 unit, single family low rent housing development in Arapaho, Wyomin
Renee Aldrich, the Seasonal Wilderness Monitor for the Mt Rose area accomplished the following during the whole term of her employment:   Campsites documented: 82 People encountered on the trail: 558  Invasive Weed Populations Documented: 19
This project is a challenged cost share agreement with the White Mountain National Forest, Androscoggin District to reconstruct the Valley Way trail. Work performed includes installing rock steps and drainage structures to correct and prevent e
Energy efficient rehabilitation/weatherization of existing Tribal residences & apartments.
New Multi-family housing units construction including infrastructure.
Native American Housing Block Grant, Competitive-NAHASDA-eligible activities including acquisition, new construction, rehanilitation of affordable housing, nsite improvement, development and rehabilitation of utilities and infrastructure, utili
Tonkawa Tribal Native American Housing Rehabilitation
NAHBG Recovery Act Grant for new construction
Siletz Tribal Housing Low Income Rentals
Site development and construction of five LEED certified single family rental homes. (1) 2 bedroom home, (2) 3 bedroom homes, (2) 4 bedroom homes one of which will be fully ADA accessible. HUD and Native American Housing Block Grant to provide
Honeysuckle Housing Development, HS-1, HS-2, HS-6, HS-7 and HS-12
The project objective is to implement the ARRA on private and state lands in Shoshone County, create and retain jobs, reduce hazardous fuels around communities, and improve forest health by thinning and pruning. Project work will provide opport
Shoshone County-Silver Valley: Idaho Silver Valley Hazardous Fuels Treatment, ARRA project #WFM-0156-04HFE.
LAND AND NATURAL RESOURCES, HAWAII DEPT OF
Monitoring and Control of Invasive Plants in Hawaii. Hawaii's extreme geographic isolation has led to evolution of Faura and Fauna that are very vulnerable to invasions by alien species. Over the past two centuries, thousands of non-native plan
Monitoring and Control of Invasive Plants in Hawaii
The award is providing transportation subsistance to purchase and transport logs from various timber sales to Sierra Forest Products.
SBA Sawmill Infrastructure Assistance Grants 2009
This project seeks to reduce, minimize or eliminate the potential for introduction, establishment and spread of invasive species, which displace and compete with native species.  Work will be performed on approximately 580 acres of industrial f
Industrial Landowner Noxious Seed Abatement
UPPER COLUMBIA RESOURCE CONSERVATION AND DEVELOPMENT COUNCIL
Kulzer BioEnergy Park.  A multiple phased biomass to energy demonstration project with combined heat and power facility for 5 MW power generation, bio-char, bio-oil, and syngas production, and other commercially marketable timber products. Site
Forest Nurseries and Gathering of Forest Products
AGRICULTURE AND CONSUMER SERVICES, FLORIDA DEPARTMENT OF
The Florida Department of Agriculture and Consumer Services, Division of Forestry will develop three hazard fuels burn teams to augment current hazard fuels management activities, contract for hazard fuel reduction through mechanical and prescr
Florida Community Fuels Management Program Phase 2
Increased control of invasive species in Mississippi.
Increased Control of Invasive Species in Mississippi
Federal Financial Assistance Award of Recovery Act Domestic Grant. USDA, Forest Service 2009 ARRA.
Grinding, Hauling & Processing Operation
All Other Miscellaneous Wood Product Manufacturing
This grant will reduce the threat of wildfire to communities and resources on state and private lands in southeast Massachusetts and restore the ecosystem through: 1) adding state fire management specialists, 2) increasing fire planning in high
USFS Southeastern Massachusetts Fuels Mitigation
NATURAL RESOURCES, MICHIGAN DEPARTMENT OF
The primary purpose is to retain, reinstate or stimulate the creation of jobs through conducting forest health management activities to control invasive species on non-federal lands.   Efforts to combat invasive species include increased awaren
Arena Road (W Lim of Albert Lea) to CSAH 6, Concrete Overlay (Tied to 2481-50 and 2481-51)  W Lim of Alden to TH 13, Heavy Bit Overlay on WB Lanes and Unbonded Concrete Overlay on EB Lanes, Tied to 24-646-12
Anderson Rd to Mesaba Ave in Duluth, Mill and Overlay, Drainage Repairs
Replace Br 9075 over Rum River at 3.7 Mi W of W Limits of Cambridge
TH 27 to N City Lim, Street Reconstruction, Grading, Paving, Curb and Gutter
S Dakota State Line (MN W State Line) to TH 75 8 Mi N of Wheaton
285th St to 1000' S of Featherstone Rd-Complete Reconstruction of Road Segment includes replacement of BR L0357 with BR 25J59
Replace BR No 89249 over Co Rd 3, Includes Approaches
Replace BR 42511 Over S Branch of the Yellow Medicine River 2.5 Mi S of TH 68, 2.9 Mi S of Minnesota, MN
TH 28 to Todd Co CSAH 11, Bituminous Overlay and Aggregate Shoulders
Metrowide Signal and Lighting Cabinet Replacement
At Hennepin CSAH 4 and Dell Road in Eden Prairie-Landscaping
SCC crews with technical guidance from the Forest Service will conduct backcountry cutting and clearing work.  Maintenance/reconstruction will consist of relocation of trails when necessary; intensive drainage and tread work, clearing trails of
Lincoln National Forest Three Rivers Trail System Maintenance
Project Title: Mt Rose Wilderness Trails Maintenance  The Humboldt-Toiyabe National Forest, Carson Ranger District manages 27,000 of the 30,000 acres of the very popular Mt. Rose Wilderness in Nevada. This project will focus on trail maintenanc
On the job training for trail work, refurbishment and heavy maintenance for up to 81 miles of trail for improved public access.  This consists of clearing logs, rocks, boulders and brush, digging drainages, building water bars for drainage, soi
The purpose of this agreement is to benefit participants of the CCC by providing opportunities for job training, personal development, conservation service, maintenance of roads, building and maintenance of trails, recreation facilities and mai
Shasta Trinity Job Partnership and Wildfire Protection
This is an agreement entered into between the Department of Ecology - Washington Conservation Corps (WCC) and the Department of Agriculture, US Forest Service.  The purpose of the agreement is to complete maintenance and restoration projects on
WCC/Olympic US Forest Service Restoration Project
NYC programs use an outdoor lifestyle and challenging projects to teach problem solving and positive living skills, promote a strong and productive work ethic, encourage learning, and build self-esteem.   Youth in the program learn essential j
Willamette National Forest - McKenzie River RD - Pacific Crest Trail Maintenance
Child Care and Development - ARRA funds currently help serve 56 eligible children in the EBCI Agelink Childcare Program.Agelink is a full time Daycare and Aftershool child Care proggram with a 3 star rating uner the north carolina rating system
TITLE: ARRA Supplemental Funding for the Child Care and Development Fund (CCDF); DESCRIPTION: Provide child care financial assistance to low-income working families and fund activities to improve the quality of child care.
CCDF-funding to enhance existing child care activities, expand on the quality and quantity of services to families and providers and create opportunities for improvement by training, replacing out dated equipment/materials, and resource materia
CCDF:  To provide child care financial assistance to low-income working families and fund activities to imporve the quality of child care. Helped families in summar courses.  Helped five families with summer classes which benefited from this pr
Provide childcare financial assistance to low income working families and fund activities to improve the quality of childcare.
The Navajo Division of Social Services, Health and Natural Resources proposes to utilize the CSBG/ARRA funds to assist children, families and communities, living in deplorable conditions, in meeting their basic living needs and enhance their op
Provide child care financial assistance to low-income working families, low-income families attending school or job training and fund activities to improve the quality of child care.
Increase payment rate for Child Care and Family Home Child Care Providers. Increase age group currently being served. Allow for employment verification. Provide training and assist providers in being in compliance with health and safety require
ARRA Supplemental Funding for the Child Care and Development Fund (CCDF); Description: Provide child care financial assistance to low -income working families and fund activities to improve the quality of child care.
EXECUTIVE OFFICE OF THE STATE OF MARYLAND
The AmeriCorps members funded The AmeriCorps members funded through the Recovery Act will engage in various activities in service activities to communities affected by the economic crisis. AmeriCorps members improve the literacy of youth, enhan
RECOVERY MD State Commission Programs Competitive
CHILDREN, YOUTH AND FAMILIES, NEW MEXICO DEPARTMENT OF
AmeriCorps State Competitive Members will:  Provide safe, secure after school programming to k-6 grade elementary students in remote rural communities in northern New Mexico.   Expand programming service into the Greater Santa Fe area and Nativ
CHILDREN & FAMILY SERVICES, NEW YORK OFFICE OF
The New York State Commission on National & Community Service's portfolio of 36 applications illustrates the commitment to expand AmeriCorps in New York State and the unprecedented need being felt by our programs and communities. The State Comm
Recovery funds are going to support the Central Dallas Ministries emergency support programs and also upscale the current neighborhood revitalization program. Emergency support programs include providing food to families, hot meals to homeless
WEST VIRGINA COMMISSION FOR NATIONAL & COMMUNITY SERVICE
The goal of the LifeBridge AmeriCorps recovery program will be to increase the number of unemployed individuals receiving the resources, services and supports they need to find suitable employment opportunities.
Phase II and completetion of In-Car Video Systems, by purchasing five (5) additional systems and two (2)servers to support video storage of same.
Town of Trumbull JAG Local Pass Through Project
Photographic Equipment and Supplies Merchant Wholesalers
Recovery AmeriCorps members address educational, environmental, and other human needs in the state of Arkansas.
EXECUTIVE OFFICE OF THE STATE OF ARIZONA
This award funds the approved ARRA AmeriCorps Formula programs that focus on activities related to volunteer generation; forest conservation and preservation; homebuilding; family literacy; community capacity and renewal; and, dropout preventio
Funded activity supported a staff position at a subgrantee site that would otherwise currently be unable to fund the position.  The subgrantee organization is focused on providing organized, professional in-school play activities that help addr
COMMUNITY AFFAIRS, GEORGIA DEPARTMENT OF
The Georgia Commission for Service and Volunteerism (GCSV) received funding from the Corporation for National and Community Service through the American Recovery and Reinvestment Act (Recovery Act) to fund AmeriCorps grants to meet community ne
AmeriCorps members focus on housing construction and weatherization, economic development, and community building activities
- using grant funds to meet matching resource requirements arising from economic downturns in the impacted communities.  Examples of services provided include:  adult literacy, English as a Second Language, education and support for families &
The award focuses on increasing the number of individuals that engage in services, the types of services, and number of volunteers serving to support local non-profit organizations; increasing the number of youth and hours of tutoring for youth
FINANCIAL MANAGEMENT, WASHINGTON STATE OFFICE OF
Recovery WA Commission Formula Prime Grant for ARRA AmeriCorps programs to carryout a national service program as authorized by the National and Community Service Act and the American Recovery and Reinvestment Act of 2009. These service activit
Since 2002, Citizen Schools' National Teaching Fellowship has been a recipient of AmeriCorps National Direct grant funds.  Citizen Schools uses AmeriCorps grant funds to recruit and deploy full-time AmeriCorps members to serve in intensive afte
Recovery - Citizen Schools National Direct
AmeriCorps members provide structured in-school student services (tutoring, enrichment activities, and classroom assistance) and after school programs for children and youth.
GREATER PITTSBURGH LITERACY COUNCIL, INC.
Recovery AmeriCorps members  primarily provide employment and skills training. Service activities include providing job readiness trainings such as résumé writing, interview and communication skills; assisting clients in employment searches;
Mackinac Trail roadway Reconstruction, includes milling exisitng surface, shoulder widening, and re-paving and all related work.
Replacing culverts, resurfacing 7.0 miles of T301 River Road. Rebuilding shoulders with DSA limestone, drainage improvements, erosion controls,road widening, tourism interpretive signing, safety signing and other saftey improvements, construct
T301 Clarion River Road Reconstruction and Tourism Infrastructure Development
Crushed and Broken Limestone Mining and Quarrying
Mining, Quarrying, and Oil and Gas Extraction
The RECOVERY ACT ROAD PROJECT grant is for the reconstruction of 5.3 miles of Dunham Siding Road to provide recreational, business, and administrative management access of Allegheny National Forest and Pennsylvania Game Commission State Game La
Reimburse the Alcona County Road Commission for labor expenses necessary to improve seven specified road-stream crossings within the Pine River watershed in Alcona County.
Pine River Van Etten Lake Watershed Road Stream Crossings
NATIONAL ASSOCIATION OF CHILD CARE RESOURCE AND REFERRAL AGENCIES
This award is a cooperative agreement between Rocky Mountain Elk Foundation and the Bitterroot National forest to enhance wildlife habitat, manage the timber resource and improve forest health.
The purpose of Los Angeles County Office of Education, Head Start-State Preschool Division’s (LACOE) cost of living (COLA) and quality improvement (QI) funds for 2009-2010 is to provide enhanced support to our agencies. The basic cost of livi
The ARRA COLA & Quality Improvement funds were used for a Cost of Living increase for staff, improving staff qualifications and assisting with the implementation of career development programs for staff that support ongoing improvement of their
ARRA ? COLA- To be used to pay for higher operating costs and to increases staff salaries and fringe benefits. The portion of the COLA under the ARRA will be available for only a 12 month period effective July 1, 2009 to June 30, 2010 to provid
Cost of Living Adjustment and Quality Improvement
This ARRA provides for ARRA Cost of Living Adjustment (COLA) and Quality Improvement Funding consistent with the provisions of Section 640(a)(5)of the Head Start and Early Head Start Program.  The Bureau's HS and EHS program  provides services
SHASTA COUNTY HEAD START CHILD DEVELOPMENT, INC.
This award provides for ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the privisions of Section 640(a)(5) of the Head Start Act for the Head Start and Early Head Start programs.  Head Start promotes the
COMMUNITY ACTION PARTNERSHIP OF SONOMA COUNTY
This award provides for ARRA Cost of Living Adjustment (COLA,) and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start and Early Head Start program.  Head Start promotes the s
Head Start and Early Head Start ARRA COLA/QI
This project addresses fundamental and challenging questions that are common to robotic systems that build their own maps and solve monitoring tasks. In particular, the work contributes to our general understanding of the interplay between sens
RI: Medium Collaborative Research: Minimalist Mapping and Monitoring
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  Recent years have witnessed a dramatic change in the goals and modus operandi of malicious hackers. In particular, hackers have realized the pote
TC: Medium: Collaborative Research: User-Controllable Policy Learning; Research being conducted with this award involves developing and evaluating a new family of user-oriented machine learning technologies to help users refine a wide range of
TC: Medium: Collaborative Research: User-Controllable Policy Learning
This project focuses on understanding the principles and methods for the design of green networks at the edge of the Internet. The total power consumption of edge networks is estimated to be quite significant, so even moderate improvements in e
NETSE: MEDIUM: COLLABORATIVE RESEARCH: GREEN EDGE NETWORKS
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).    Great progress has been made in recent years in detecting massive planets orbiting other stars. These exciting discoveries are an important ste
NetSE:Medium:Collaborativ e Research: Green Edge Networks
The fundamental differences between multi-hop networks and point-to-point settings indicate that leveraging MIMO gains in multi-hop networks requires a paradigm shift from high SNR regimes to interference-limited regimes. This project undertake
NeTS: Medium: Collaborative Research: MIMO-Pipe Modeling, Scheduling and Delay Analysis in Multi-hop MIMO Networks
The PI develops methods in function estimation and inference, using shape-restricted regression splines. The work includes three broad areas in estimation and inference. First, generalized multiple regression models is investigated, where the m
Probabilistic and decision-theoretic planning, which operates under conditions of uncertainty, has important applications in science and engineering, but such stochastic methods have been under-utilized because these planners do not scale to la
RI: Medium: Collaborative Research: Solving Stochastic Planning Problems Through Principled Determinization
A four-pixel prototype heterodyne focal plane array based on Monolithic Millimeter Integrated Circuit technology will be built. The purpose is to demonstrate the feasibility of a scalable focal plane array technology based largely on technology
Scalable MMIC Receiver Array Development for Millimeter-wave Spectroscopy, Polarimetry,and Interferometry
The principal investigator will pursue several lines of research motivated by three deep open questions in the theory of word-hyperbolic groups. (1) Is every hyperbolic group residuall finite? If so, then in fact word-hyperbolic groups satisfy
Separability and logic in geometric group theory
Liquid crystals are important both for device and biological application. Liquid crystals are in TV’s, clocks and many other applications. They are also the phases of the walls of every living creature cell. The interaction of nanoparticles w
Effect of the Nanoparticle Surface Termination on the Nanoparticle-Smectic Liquid Crystal Interaction: Order/Disorder Effect
Technical. The goal of this focused research group (FRG) proposal is to achieve an atomic-level understanding of the growth and novel properties of switchable oxide hetero-interfaces, with advanced properties and new functionalities. The idea i
ARRA Switchable two-dimensional materials at oxide hetero-interfaces
Quantile Regression for Multivariate Time Series Models with Functional Coefficients  Quantile regression receives increasing attention in econometrics and statistics for its advantages over mean regression.  For multivariate nonlinear time ser
Quantile Regression for Multivariate Time Series Models with Functional Coeffici
The intellectual merit of the proposed research is that, by using a unique combination of experiment and theory, this research will provide a useful understanding of the phase behavior and structures of this new class of mixed polyelectrolyte b
Novel Mixed Brushes with Tunable Internal Structures of Length Scales
The crystallographic textures generated by dry sliding wear in metallic elements and alloys are investigated in this project. These crystallographic textures develop in the severely plastically deformed (SPD) nanograin layers that are produced
Crystallographic Textures Induced by Dry Sliding Wear in Metals
, liquid crystal displays. As stated by the Nobel Prize winner in the field, P.G. de Gennes, ''...the study of liquid crystals is complicated because it involves...a certain sense of vision in three-dimensional space in order to visualize compl
Coherent Anti-Stokes Raman Scattering and Fluorescence Confocal Polarizing Microscopy of Three Dimensional Structures in Liquid Crystals
Collaborative Research: Three-Dimensional Microstructural and Chemical Mapping of Solid Oxide Fuel Cell Electrodes: Processing, Structure, Stability, and Electrochemistry
The PI's three-year research program will investigate fundamental aspects of random variables which can be understood within the framework of Wiener spaces. Specifically, in the context of the Wiener process W (standard Brownian motion), if a r
Density and Tail Estimates via Malliavin Calculus, and Applications
TECHNICAL SUMMARY A variety of useful functional materials can be produced by adsorption of polymeric molecules, nanoparticles, or a combination of these components to liquid/liquid or liquid/solid interfaces. Applications of these materials re
Structure and Mechanics of Self-Assembled Polymer Films at Liquid Interfaces
There has been an abundance of research in recent years on polymeric amphiphiles as drug carriers. These materials, formulated as micelles, vesicles and emulsion droplets, can exhibit greater stability and improved control over release compared
DEVELOPMENT OF MULTIFUNCTIONAL POLYPEPTIDE AMPHIPHILES AS DRUG DELIVERY VEHICLES
The goal of this proposal is to create and understand active cell culture substrates using surface shape memory and, in parallel, to study unique properties of shape memory polymers (SMPs) that promise broad application in biological and biomed
Active Cell Culture Using Surface Shape Memory
Interstellar and intergalactic gas is pervaded by relativistic charged particles known as cosmic rays, which account for a significant fraction of the energy density in the gas. A fluid theory of cosmic rays has been developed in which collisio
Studying young stellar systems, analogs to the early solar system, is vital to understanding our origins. One component of this growing area of research is to investigate how volatile molecules such as water, CO, and simple organic molecules ev
Volatiles in Disks Around Young Stars: Disentangling Our Origins
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).This study will test hypotheses about the responses of marine birds to spatial and temporal variability in ocean processes in the Bering Sea and Al
Bering Sea Retrospective: seabirds as indicators of spatial variability and temporal change
Dr Strauss and his team will develop a software pipeline to analyze images from large sky surveys in a systematic way to optimize their use for weak-lensing measurements: light from a distant galaxy is bent by the gravity of all the matter that
Analyzing Deep Imaging Data: State of the art algorithms for weak lensing and galaxy formation
Collaborative Research on Mathematical Constructs for Multiphase Complex Fluids Project Summary The projects in this proposal are to develop mathematical constructs for multiphase complex fluids(MCFs). Complex fluids are distinguished from visc
Collaborative Research on Mathematical Constructs for Multiphase Complex Fluids
'In this project, Dr. Ben Oppenheimer of the American Museum of Natural History (AMNH) and Dr. Lynne Hillenbrand of the California Institute of Technology will conduct a survey of nearby stars to detect planetary companions. They have previous
COLLABORATIVE RESEARCH - Project 1640: Hyperspectral Imaging Survey of Nearby Stellar Environments
'This project is to investigate the role of convection on dynamic stability of the three-dimensional incompressible Euler and Navier-Stokes equations. The main objective is to show that convection together with incompressibility plays an essen
Collaborative Proposal: The role of convection on dynamic stability of 3D incompressible Navier-Stokes equations
Under this award, Dr. P. Frank Winkler (Middlebury College) will carry out a program of research with the overarching theme of increasing our understanding of how supernovae explode, how their prodigious energy release affects their host galaxi
RUI: Supernova Ejecta, Shocks, and the Interstellar Medium
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  This is a joint project between the Massachusetts Institute of Technology (MIT- USA) and the University of Bayreuth (UB- Germany). Catalysts have
Materials World Network: In-situ Investigation of Model Multi-component Catalyst Systems
The objective of this research is to constrain star formation models with high dynamic range simulations. Current star formation simulations are based on unphysical initial conditions or artificial driving forces that mimic the energy injection
Star Formation in the Turbulent ISM with Realistic Large-Scale Forcing and Initial Conditions
Dr. Kumar's research program will address two fundamental issues regarding long duration Gamma Ray Bursters (GRBs). The first is the mechanism for production of the prompt gamma-ray emission and how the energy in an expanding jet is converted i
Gamma-ray Bursts, Progenitor stars & Relativistic Jets
'A Long Baseline Investigation of Clouds, Haze, and Methane Distributions on Titan.' The primary goals are to retrieve Titan's time-dependent distributions of methane and haze using ground-based, Hubble Space Telescope, and the Cassini Imaging
'Dr. Djorgovski and his team will use the data stream from the NASA-funded Catalina Sky Survey (CSS) to search for transient astronomical objects including flare stars, gamma-ray bursts, and strong microlensing events. That survey uses two wid
The Catalina Real-Time Transient Survey (CRTS)
This award will support an investigation of Holocene glacier fluctuations in the Scoresby Sund region of central East Greenland (~70-72°N, 22-28°W) along a transect from a coastal maritime setting to the continental conditions adjacent to the
Collaborative Research: Sensitivity of local glaciers in central East Greenland to Holocene climate change
Collaborative Research: Sensitivity of Local Glaciers in Central East Greenland to Holocene Climate Change
The uppermost 200 kilometers of geologically stable regions behaves nearly rigidly over geological times. The temperature in this region, called the lithosphere, gradually increases with depth. The rock near the base of the lithosphere deforms
Geodynamics of the Base of the Lithosphere and Ultraslow Ridge Axes
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).   The Arctic is undergoing structural and functional changes that appear to be the result of climate change, including shifts in vegetation distri
Collaborative Research: Environmental changes alter the carbon cycle of high Arctic ecosystems: Shifts in the ages and sources of CO2 and DOC
In this project funded by the Inorganic, Bioinorganic, and Organometallic Chemistry Program of the Chemistry Division, Roald Hoffmann of Cornell University will use theoretical methods to understand structure and bonding in solids under high pr
CHEMICAL BONDING ACROSS THE PERIODIC TABLE
The role of large strike-slip faults in the evolution of the Himalayan-Tibetan orogen is a topic of continued debate, with considerable focus on the Altyn Tagh and Karakorum fault systems. Two primary families of models have emerged regarding t
Collaborative Research: Continuation and Termination the Karakorum and Karakax Faults in Western Tibet: Implications for the Role of Regional Strike-
Professor Adam E. Cohen of Harvard University is supported by an award from the Experimental Physical Chemistry Program to develop a trap capable of suppressing the Brownian motion of single small molecules in solution, with molecular diameters
Trapping single small molecules in solution
The goal of the proposed work is to understand the dynamics of the Earth?s interior and the long-term evolution of our planet. The motion of tectonic plates and the attendant earthquakes are surface expressions of a large-scale flow in the inte
Collaborative Research: Thermochemical Models of Mantle Dynamics and Plate Motions
Deep earthquakes, some of which are among the largest and most damaging of all earthquakes, have been a paradox since their discovery in the 1920s. The combined increase of confining pressure and temperature with depth inhibits frictional slidi
Faulting under high confinement: Experimental investigation and model development
The Organic and Macromolecular Chemistry Program in the Chemistry Division at the National Science Foundation supports Professor Carl C. Wamser of Portland State University. His research proposes to develop the next generation of solar cells th
Nanofibrous Conductive Polymers from Aminophenylporphyrins: Mechanisms for Conductivity and Applications in Solar Cells
Nondestructive imaging methods such as X-Ray Computed Tomography (CT) yield high-resolution 3 D representations of pore space and fluid distribution within porous materials. Steadily increasing computational capabilities and easier access to in
Development of Efficient X-Ray CT Image Segmentation Techniques for Quantitative Analysis of Phase Distributions and Flow Processes in Porous Media
This project will focus on the development of methods for the formation of N-alkyl pyridone containing structures, including amino acid homologues. N-Alkyl pyridones are interesting motifs due to their prevalence in natural products as well as
RUI: Synthesis of N-Alkyl Pyridones: Mechanism, Methodology and Application to Organic Materials
Traditionally, faults were thought to accommodate slip in one of two ways: Stick-slip motion, in which long periods where the fault is essentially locked are punctuated by brief episodes of rapid slip (earthquakes), and steady creep at plate te
Theoretical earthquake nucleation, with applications to creep fronts, tremor, and slow slip
Intellectual Merit:  Heat transfer from crystallizing granitic plutons has fundamental consequences for crustal heat-flow, metamorphism, hydrothermal systems, wall-rock assimilation, duration of volcanic centers, and pluton growth. Current ther
COLL. RESEARCH: INCORPORATING TEMPERATURE-DEPENDENT PHYSICAL PROPERTIES INTO NUMERICAL MODELS
The project investigates the role of deformation in the distribution of titanium (Ti) and other trace elements in quartz over a wide range of temperature and deformation conditions in nature and experiments. The mobility of Ti in deforming quar
Collaborative Research: Titanium in Deforming Quartz and the Thermo-mechanics of Detachment and Thrust Systems
'This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).' This project, which is a collaboration between researchers at Western Washington University, the University of Alabama at Tuscaloosa, and Boston
The Inorganic, Bioinorganic, and Organometallic Chemistry Program supports the efforts of Professors Frederick M. MacDonnell and Norma S. Tacconi of the University of Texas at Arlington for the investigation of an integrated approach towards th
Solar Hydrogen Generation Using Supramolecular Photocatalysts
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5)  Recently, a new mode of coupled deformation and weak seismic radiation has been discovered in numerous subduction zones globally. Slow slip and we
Investigation of source spectral models and scaling for slow slip processes in subduction zones
The glaciers and icefields of coastal southeast Alaska and the adjacent areas of Canada are among the most dynamic on the planet, and they are shedding mass at a dramatic rate due to climate warming and the dynamics of tidewater glacier retreat
Investigating Hydrologic Loading in Southeast Alaska Using GRACE and GPS Data
The main thrust of the research program of the Louisiana Tech University TJNAF group involves parity violating electron scattering reactions, a program which will challenge our understanding of nucleon structure, probe the dynamics of QCD symme
Precision Electroweak Measurements at Jefferson Lab
This Small Business Innovation Research Phase I research project aims to develop a wearable computer system with an innovative multimodal input mechanism. The objective of this research is to assess the feasibility, efficiency, and quality of d
SBIR Phase I: Voice-based Wearable Computers for Emergency Medical Services
This SBIR Phase I research project will demonstrate an opto-fluidic chip-scale bio-sensor system for label-free, high-throughput, real-time monitoring and detection of dynamics of multitude of biochemical reactions in small volumes and at low c
SBIR Phase I: High sensitivity nanoplasmonic biosensors
SBIR Phase 1:  Nano-scale Engineering via Grid-scale Computing: Designing, Optimizing and Manufacturing Cancer Therapeutics
Nano-scale Engineering via Grid-scale Computing: Designing, Optimizing and Manufacturing Cancer Therapeutics
This Small Business Innovation Research Phase I project develops an inexpensive rugged sensor for explosives detection with ability for wireless data transmission.  The sensor can identify analyte by changes in the electronic properties of the
SBIR Phase I: Automated Identification and Rapid Detection of Explosives Using Piezoresistive Micro- and Nano-Cantilever Arrays.
Other Measuring and Controlling Device Manufacturing
This Small Business Innovation Research Phase I project will focus on developing a desktop-specific distributed architecture to provide enterprise grade, highly available and scalable virtual desktop systems that cost no more than a regular PC.
SBIR Phase 1: Next Generation Virtual Desktops
This Small Business Innovation Research Phase I research project addresses distributed structural integrity monitoring of infrastructure systems such as bridges and pipelines. The existing solutions for structural state sensing are expensive, l
SBIR Phase I: An RF Radiation Empowered Sensing Method for Low Cost Structural State Monitoring
Radio and Television Broadcasting and Wireless Communications Equipment Manufacturing
This Small Business Innovation Research Phase I research project is aimed at developing an innovative Radio Frequency Identification (RFID) based warehouse management system utilizing a new patent-pending component that will help to address fun
SBIR Phase I: An enhanced UHF RFID system for warehouse management
7037 NSF SBIR UNCD AntiCoagulation Device
This Small Business Innovation Research Phase I project will investigate UNCD(R), a nanocrystalline from of smooth, thin diamond, as an anti-thrombotic coating for implantable medical devices. One of the largest problem with implantable circula
SBIR Phase I: Development and Characterization of Bio-inert UNCD films for Implantable Devices to Eliminate Blood Clotting
All Other Basic Inorganic Chemical Manufacturing
This Small Business Innovation Research Phase I project aims to accelerate construction of humane, efficient and intuitive user interface (UI) - a system of small, wireless, gesture-sensitive displays that act in concert as one interface. Peopl
SBIR Phase I: Siftables - Distributed, Gestural Human Computer Interaction
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  The transmission cycle of many important infectious agents includes not only the hosts but also their environments. After infection of a host wit
ARRA Collaborative research: Transmissibility of infections caused by intermittendly shed pathogens capable of environmental persistance. Relating theory to experimental data
This proposal concerns the development of a means for efficient computerized search for combinatorial objectswith a specified isomorph-invariant property. One of themost powerful techniques developed by the computer science and operations resea
Computerized Search for Combinatorial Objects
Software bugs cost the U.S. economy over $60 billion each year. Promising bug-detection technology depends on high-performance logic solvers for Satisfiability Modulo Theories (SMT), which employ sophisticated algorithms to check large formulas
SHF: Small: Collaborative Research: Flexible, Efficient, and Trustworthy Proof Checking for Satisfiability Modulo Theories
Computational Mathematics has been central to the Program in Applied and Computational Mathematics(PACM) since its inception in the mid 1970s. This tradition is rooted in the traditional, in uential and powerful fields of computational fluid dy
A New Initiative in Computational Mathematics at Princeton
Presence of a well-structured market is necessary for efficient and flexible use of licensed spectrum bands, and for fair pricing of spectrum usage. The goal of this project is to design radio spectrum markets that allow trading of spectral res
NetS: SMALL: Collaborative Research: Financial Dynamics of Spectrum Trading
Numerical methods are the future of computation in algebraic geometry. The reason for this is that increases in computing power will be due to massive parallelization and symbolic algorithms do not appear to be parallelizable while numerical al
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).   Historical static spectrum assignment has led to a critical spectrum shortage. While new prominent wireless technologies starve for spectrum, la
NeTS: Small: A Practical and Efficient Trading Platform for Dynamic Spectrum Distribution
Non-Linear Processing and Coding for Compressive Sensing with Aplications in Imaging:     Recently, the new field of compressive sensing (CS) has emerged with the promise to revolutionize digital processing broadly. Surprisingly, Nyquist-rate
CIF:SMALL:Non-Linear Processing and Coding for Compressive Sensing with Applications in Imaging
Opportunistic communication leverages communication opportunities arising by chance to provide significant performance benefit or even enable communication where it would be impossible otherwise. This project develops algorithms, techniques, an
NeTS: Small: Predictable Optimization of Opportunistic Communication
Robotic Sensor Networks (RSNs) are finding increasing use in critical applications such as surveillance, environmental monitoring, emergency response and search-and-rescue. With recent advances in embedded technologies, devices that can be used
NetSE: Small: Game Theoretic Coverage and Connectivity Services
Wireless Mesh Networks have emerged as a solution for providing last-mile Internet access. By exploiting advanced communication technologies, they can achieve very high rates. However, effectively controlling these networks, especially in the c
NeTS: Small: Collaborative Research: Effective Control of Wireless Networks via Topology Adaptation and Randomization
Increasingly, the Internet is used to distribute content on massive scale. Massive content distribution causes shortage of network capacity, increases costs of service providers, and impairs quality of user experience. This project develops adv
NeTS:  Small; Fundamental Methods and Heuristics for Advanced, Network-Centric Content Distribution
'This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).'  In the 21st century, the dominant computing platform has shifted to multicore chips that implement cache-coherent shared memory and run multi-t
ARRA SHF:Small: Managing Non-Determinism in Multithreaded Software and Hardware
A fundamentally different approach for circuit design that has recently gaining popularity is sub-threshold circuits, where the power supply is set below the transistor threshold voltage to obtain energy savings when speed is not the primary co
ARRA: SHF: SMALL: 3D INTEGRATION OF SUB-THRESHOLD MULTI-CORE CO-PROCESSOR FOR ULTRA LOWER POWER COMPUTING
The performance of network users' best effort flows, e.g., file transfer delays and web browsing responsiveness, depends on the resources they are allocated over time. When varying traffic loads share these resources and/or wireless nodes' tran
NeTS: Dynamic Coupling and Flow-Level Performance in Data Networks: From Theory to Practice
This project provides challenging test data and benchmarks designed to advance stereo vision methods to a level of practical relevance. It aims to bridge the gap between the sophisticated but brittle methods that perform best on current benchma
RI:Small:RUI: Towards the Next Generation of Stereo Algorithms
Much of the Internet's growth occurs in domains beyond the reach of current measurement techniques and platforms, such as behind NAT boxes and firewalls or in regions of the Internet not exposed by public BGP feeds. This work is motivated by th
NeTS: Small: Parallax - Leveraging the Perspective of Ten Million Peers
Our central hypothesis is that the slow electrical bursting oscillations and episodic bursting that are often exhibited by pancreatic islets, and that have the same period as insulin oscillations observed in vivo, are driven by oscillations in
A Mathematical Study of the Biochemical and Electrical Dynamics of Pancreatic Islets
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  This project models decision-making and learning in complex environments. One would expect most decision makers to be aware of such complexity an
Collaborative Research: Symmetry, Ambiguity and Frequencies
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  The support of animals in ecosystems ultimately comes from two sources: primary production within an ecosystem (e.g. newly grown plant material)
ARRA Collaborative Research: Terrestrial support of lake food webs: A Multi-Isotope Approach
Animal cells divide themselves by assembling a contractile ring of actin myosin around the cell equator which constricts the cell surface between duplicated chromosome sets at the end of mitosis. Classical experiments suggest that cells 'know'
ARRA Collaborative Research: Cytokinetic Furrow Specification in Sea Urchin Embryos
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  Reforestation of tropical landscapes that were cleared of trees is a goal that has important implications for conservation biology, for developin
Spatial patterns of tropical forest restoration in an agricultural landscape
Vibrio parahaemolyticus as a model system to determine bacterial adaptation to changes in the marine coastal ecosystem
VIBRIO PARAHAEMOLYTICUS AS A MODEL SYSTEM TO DETERMINE BACTERIAL ADAPTATION TO CHANGES IN THE MARINE COASTAL ECOSYSTEM
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  Mammals, including humans, have extremely high genetic diversity among the genes involved in the immune system. The resulting differences among i
PATHOGEN ADAPTATION TO SPECIFIC HOST GENOTYPES: IMPLICATIONS FOR HOST-PATHOGEN COEVOLUTION
The project addresses fundamental research issues in a topical area of electronic/photonic materials science having technological relevance. Lowering the cost barrier associated with Ge substrates is a key element in making advanced III-V photo
COLLABORATIVE PROPOSAL: LOW-COST SUBSTRATES FOR III-V PHOTOVOLTAICS BY SELF-TEMPLATED SELECTIVE EPITAXIAL GROWTH OF GERMANIUM ON SILICON
Advanced computing and data acquisition technologies have made possible the gathering of large multivariate data sets in many fields. Efficient multivariate statistical analysis tools for such data sets are highly sought after. Among the existi
Data Depth for Nonparametric Multivariate Analysis: Goodness-of-FitTests Based on Spacings, Classification, and A Coherent Framework forData Depth
Reducing the size of a magnetic material down to sub-micrometer or nanometer dimensions changes the energetics of the system and leads to vastly different magnetic landscapes and dynamic excitations that are important for a wide range of presen
Dynamics in Patterned Magnetic Nanostructures: Spin-Wave Excitations and Propagation
TECHNICAL SUMMARY This award supports theoretical research that will study pattern formation in fibers and in self-assembled gels with charged units and with competing interactions. Nanopatterns in gels of charged chains with self-attracting in
Segregation in Multicomponent Macromolecular Systems
Dr. Cornelia Lang (University of Iowa) will carry out an observational program to study the impact of the young massive stellar population on the interstellar medium in the central regions of the Milky Way galaxy. The physical properties of thi
The Impact of Massive Stars and Clusters on the Interstellar Medium in the Galactic Center
The project is aimed at obtaining constructive proofs of existence of various particular solutions of the multi-dimensional compressible Euler and potential flow equations. Constructive proofs provide not only mathematical rigor, but also detai
Constructive Existence Proofs for PDE in Multi-Dimensional Compressible Inviscid Flow
Dr Zabludoff will study Lyman-alpha blobs, large clouds of glowing gas in the distant Universe that may represent the adolescence of today's brightest galaxies. She and her team will complete two complementary, blind surveys to search for Lyman
Uncovering the Nature of Lyman-alpha Nebulae in the Distant Universe
Interactions between the interstellar medium (ISM) of a disk galaxy and the intracluster medium (ICM) of a massive cluster of galaxies will strip gas from infalling galaxies and can lead to color and morphological changes. These interactions ca
Investigations of ram pressure stripping in realistic cluster environments with a multiphase ISM
the Navier-Stokes equations, which evolve on its “fluid” domain, coupled to the Lamé system of elasticity, which evolves on its ‘solid” domain. The coupling between the two disparate fluid and solid dynamics takes place between the bou
Analysis, Computation, and Control of Coupled Partial Differential Equation Systems
The Volcanism in the Arctic SysTem (VAST) project is investigating the effects of both tropical and Arctic volcanic eruptions on climate change in the Arctic. New paleoclimatic records are being developed and global climate models are being use
Regional Climate Modeling of Volcanic Eruptions and the Arctic Climate System
The Materials World Network for Structure-response Relations of Advanced Diagnostic Tools comprises a research and education partnership among the Macromolecules and Interfaces Institute at Virginia Tech, the School of Physics at the University
Materials World Network: Structure-Response Relations of Advanced Diagnostic Tools
'Exploring the Collisional and Dynamical Evolution of Asteroids and Comets.'  We propose to model the collisional and dynamical evolution of the asteroid belt, Hilda, and Trojan asteroid populations to probe how smal bodies have been shaped and
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5)  This Materials World Network Award by the Solid State Materials Chemistry program and the Office of Special Programs in the Division of Materials
Materials World Network: Approaches to the Coupling of Dilute Spins in Oxides
Funds are provided to collect baseline winter information on the overwintering physical and biological characteristics of three important Arctic Seas: The Bering Sea, the Chukchi Sea, and the Beaufort Sea. Understanding of seasonality, and part
Collaborative Research: A winter expedition to explore the biological and physical conditions of the Bering, Chukchi, and Southern Beaufort Seas
Dr. Romanowsky and his team will measure the motion of stars in the outer regions of elliptical galaxies. A European collaboration has already probed the central regions of such galaxies, finding an abundance of internal structures that are und
Probing the fundamental halo properties of early-type galaxies using a new technique for wide-field stellar kinematics
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).The PI's overarching goal is to investigate short-term Arctic climate predictability and to improve understanding of the mechanisms that give rise
Short-term Predictability of Arctic Climate
The goal of this project is to determine how plants, microbes and soil invertebrates interact to drive changes in soil organic matter and carbon sequestration with ambient and increased soil nutrient availability in the dominant upland arctic t
Collaborative Research: A Biotic Awakening: How Do Invertebrates, Microbes & Plants Determine Soil Organic?
The Arctic region is experiencing a period of rapid warming, unprecedented in history. Long-term data sets are rare, but key to understanding recent change in Arctic ecosystems. In 1971, NSF funded the International Biome Projects (IBP) - Tundr
: Re-sampling historic sites to track global change in Artic aquatic ecosystems
'This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).'  Professor Carol Korzeniewski of Texas Tech University is supported by the Analytical and Surface Chemistry Program in the Division of Chemistry
Elucidating Processes that Limit Energy Transfer in Electrocatalysis
This research focuses on combining foundational and lightweight formal  methods to verify the safety, security, and dependability of  large-scale software systems. Foundational approaches (to formal  methods) emphasize expressiveness and genera
TC: Large:Collaborative Research: Combining Foundational and Lightweight Formal Methods to Build Certifiably Dependable Software
Emily Carter of Princeton University is supported by an award from the Theoretical and Computational Chemistry Program to pursue the development of accurate and efficient ab initio methods for application to very large molecules. Her goal is to
Linear Scaling Electronic Structure Methods for Molecules and Materials
Obtaining physiological/behavioral data from human subjects in their natural environments is essential to conducting ecologically valid social and behavioral research. While several body area wireless sensor network (BAWSN) systems exist today
ARRA: NETSE: LARGE: COLLABORATIVE RESEARCH: FIELDSTREAM: NETWORK DATA SERVICES FOR EXPOSURE BIOLOGY STUDIES IN NATURAL ENVIRONMENTS
TC: Large: Collaborative Research: Combining Foundational and Light weight Formal Methods to Build Certifiably Dependable Software. This National Science Foundation award is a part of a collaborative research with Princeton University and Yale
TC: Large: Collaborative Research: Combining Foundational and Lightweight Formal Methods to Build Certifiably Dependable Software
'This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).'   One of the greatest challenges for modern science is trying to predict the future implications of global climate change. While significant pro
RUI: Using the Products of Volcano-Ice Interaction to Constrain Paleo-ice Conditions II:  Documenting Fluctuations in Continental Ice-sheets
Quantifying the Effects of Large-Scale Vegetation Change on Coupled Water, Carbon and Nutrient Cycles: Beetle Kill in Western Montane Forest We are quantifying how rapid, extensive changes in forest structure and composition associated with Mou
ETBC: Collaborative Research: Quantifying the Effects of Large-Scale Vegetation Change on Coupled Water, Carbon, and Nutrient Cycles: Beetle Kill in Western Montane Forests
The Longmen-Shan Fault (LSF) located at the east margin of the Tibetan Plateau in western China is featured by active tectonics. It was broken in total length of 300 km with the maximum slip larger than 9 m in the devastating M8 Wenchuan earthq
Study of Coseismic Damage and Post-mainshock Heal on the Longmen- Shan Fault Ruptured In The 2008 M8 Wenchuan Earthquake in China
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). This project, supported by the Experimental Physical Chemistry Program and conducted in the laboratory of Professor F. Fleming Crim at the Univers
Vibrationally Controlled Reactions of Complexes in Liquids and Gasses
This research award in the inorganic, Bioinorganic and Organometallic Chemistry program supports chemistry by Professor Bradley D. Fahlman at Central Michigan University to develop new materials for next-generation nonvolatile memory devices (e
RUI: Precursor Design and Atomic Layer Deposition of High-k Dielectric Thin Films
Intellectual merit - Fluid flow in subduction zones has broad affects the generation of arc magmas, the formation of continental crust, the geochemical evolution of the mantle, and the generation of Benioff zone seismicity. Yet many outstanding
Tracing Evidence of Fluid Flow in Eclogite, Blueschist and Amphibolite Blocks in Subduction Zone Melanges
The Iodine-Xenon and Plutonium-Uranium-Xenon radioactive decay systems are the only ones that can provide constraints on the timing and rates of degassing from the Earth's mantle during the first couple hundred million years of the Earth's hist
Xenon Isotopes in Mid Ocean Ridge and Ocean Island Basalts: implications for the volatile evolution of the Earth
Nuclear magnetic resonance (NMR) spectroscopy is the single most important experimental technique used by chemists to deduce the structure of new organic compounds. It capitalizes on the fact that certain types of atomic nuclei, most importantl
Structure Determination by Computation of 1H NMR Chemical Shifts
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5)  The 12 May 2008 Mw 7.9 Wenchuan, China earthquake is the largest intraplate earthquake recorded by modern geophysical observations. It ruptured un
Kinematic and dynamic rupture characterization of the 2008 Ms 8 Wenchuan earthquake sequence
The Phase I Small Business Innovation Research project investigated a news/blog analysis system to support the commercialization of a product for market research and trends analysis. By performing natural language / statistical analysis on roug
Identifying and Interpreting Trends through News/Blog Analysis
This Small Business Innovation Research Phase I project applies tomaterial & process development of products from scrap (recycled) thermoplastic composite materials with microballoon fillers.
SBIR:Innovative Recycled Microballoon Thermoplastic Sandwich Composites
method for ICAR ATRP will allow, in the near future, a significant decrease in the generation of waste for all companies which are going to use ATRP technology for producing new polymeric materials.
SBIR Phase I: Adapting ATRP to Industrial Scale Production
This Small Business Innovation Research (SBIR) Phase I project will develop innovative water disinfection unit based on solid state UV LED lamps for compact point-of-use and point-of-entry water purification reactors. Accomplishment of the prop
SBIR Phase I: UV LED Lamp Based Water Disinfection for POU Compact Purification Systems
This Small Business Innovation Research Phase I project aims to demonstrate the feasibility of fundamental improvements to OS update technology. These improvements would allow system administrators to apply OS patches faster than current practi
SBIR Phase I: Enabling Non-disruptive Updates in Order to Improve OS Security
This Small Business Innovation Research Phase I project aims to develop a new material and methodology to design comfortable, custom earpieces, based on shape-memory polymers. The work focuses on these adaptive self-adjusting materials that con
Injection-molded Thermoset Shape-memory Polymers with Enhanced Acoustic Properites
This Small Business Innovation Research Phase I project will develop a novel membrane based on functionalized multi-walled carbon nanotubes.  This membrane will radically outperform conventional membranes used for water separation from ultra-lo
Functionalized multi-walled carbon nanotubes for making highly efficient waer separation membranes for ultralow sulfur diesel fuels.
The production and purification of proteins remains a rate-limiting step for basic and applied research as well as for commercial production.  The general approach for the production of protein requires biomass production in multiple liters of
Fully Integrated Seamless Protein Production and Purification System
Biological Product (except Diagnostic) Manufacturing
This Small Business Innovation Research Phase I project addresses the need for more cost effective, carbon/carbon (C/C) composites with improved properties.  Microwave processing will be investigated to enhance densification of C/C composites t
Lower Cost Carbon-Carbon Composites Densified by Microwave Heating
Carbon and Graphite Product Manufacturing
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  This Small Business Innovation Research Phase I project will develop and commercialize an intelligent software power management solution for mult
SBIR Phase I: Intelligent Software Power Management on Multicore Systems
This Small Business Innovation Research Phase I project will develop and characterize lead-free adhesives with very high thermal and electrical conductivity for wide bandgap semiconductor packaging. The company will build on its IP portfolio of
Lead Free Sintering Adhesives for Electronics Thermal Management
This SBIR Phase I project will create a content and delivery platform to facilitate interactive learning for career education ? addressing the application in support of teaching and/or learning subtopic. The project will create a prototype of t
This Small Business Innovation Research Phase I project is to develop a tunable, low power miniaturized laser which can be applied to a wide variety of sensing applications.  The laser will use thermal tuning and is expected to provide a tuning
Photosynthetic organisms contain protective mechanisms that allow them to dissipate excess solar energy not needed for photosynthesis. This protective process is called nonphotochemical quenching (NPQ). Among its critical components are xanthop
The Role of Xanthophylls in the Mechanism of Nonradiative Energy Dissipation in Photosynthesis
The Opportunities for Enhancing Diversity in Geosciences (OEDG) initiative is a collaborative effort between the University of San Diego and Ocean Discovery Institute that builds on a five year pilot study.  The pilot project, facilitated by th
Collaborative Research: OCEAN LEADERS - Developing diverse leadership for the next generation of geoscientists. A proposal for Track 2 funding.
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).    The investigator and her colleagues consider a novel high order adaptive semi-Lagrangian approach for kinetic plasma simulations. The major cha
A High Order Adaptive Semi-Lagrangian WENO Method for the Vlasov Equation
This grant supports research in adapting and optimizing Markov Chain Monte Carlo methods to compute Bayesian models on large data sets resident on secondary storage, exploiting database systems techniques. The work will seek to optimize computa
III: Small-Collaborative: Efficient Bayesian Model Computation for Large and High Dimensional Data Sets
This proposal is awarded using funds made available by the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). The research objective is the development of new discretization methods for complex models driven by partial different
Special finite element methods based on componenet mode synthesis techniques:analysis and applications
This collaborative research project is being undertaken by Dr. David L. Bourell, University of Texas at Austin, and Dr. Khalid M. Elghany, Central Metallurgical R&D Institute, Egypt, to evaluate and optimize freeform fabrication processes for p
US Egypt Cooperative Research: Freeform Fabrication of Porous Metallic Structures
Traditionally, collisions in wireless networks have been treated as a challenge, and a lot of research has been devoted on mechanisms    that can avoid them. If however the information contained in the packets that collide can be obtained even
CNS: NETS: SMALL: Collaborative research: Collision: Friend or Foe?
This research develops the algorithmic and computational framework needed for a judicious assessment of the observation impact in air quality modeling. Novel algorithms in the framework of model-constrained optimization will allow to account fo
Collaborative Research: A Computational Framework for Assessing the Observation Impact in Air Quality Forecasting
The key objective of this research is to combine the strength of the immersed interface method (IIM), hierarchical grids, and the level set method for accurate and and efficient simulation of interface problems. In particular, the investigator
The immersed interface method (IIM) for interfaces immersed in fluids
Currently, one of the most important research problems encountered in molecular biology, bioinformatics, and systems biology consists in deciphering the mechanisms that lie at the basis of gene regulatory networks. The importance of gene regula
CIF: Small: Efficient Signal Processing Algorithms for Inference of Gene Regulatory Networks
SHF: Small: Co-Processors for High-Performance Genome Analysis This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  This research develops novel techniques for applying the heterogeneous execution m
SHF: Small: Co-Processors for High-Performance Genome Analysis
In programming languages research, there is a strong trend toward  extremely PRECISE TYPE SYSTEMS, which can encode and verify extremely detailed assertions about the behavior of programs and the structure of the    data they manipulate.  Howev
Goal: to develop computationally efficient and accurate methods for imaging physically significant parameters, using diffusely scattered light.      Optical sensing and imaging will continue to become more important for in vivo medicine. In mos
CIF:Small; Optical Diffusion Tomography, with Application to in Vivo Fluorescence Resonance Energy Transfer Imaging
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).     Wireless Mesh Networks have emerged as a solution for providing last-mile Internet access. By exploiting advanced communication technologies,
NeTS: Small Collaborative Research:  Effective Control of Wireless Networks Via Topology Adaptation and Randomization
Computer systems such as personal computers and embedded systems are increasingly pervasive. People's everyday lives depend on these systems. Therefore, they must be high-confidence. To boost system performance, hardware and software are often
Automata-Theorectic Approach to Hardware/Software Co-Verification
Energy-efficient wireless communication is critical for long-term sensor network applications, such as military surveillance, habitat monitoring and infrastructure protection. To reduce the energy costs of RF listening, a node has to reduce its
NeTS: Small: Addressing Research Challenges in Low-Duty-Cycle Wireless Sensor Networks
The scaling of integrated circuits (ICs) into the nanometer regime has thrown up new challenges for designers, foremost among which are variations in the characteristics of IC components. Variations threaten to diminish the fundamental benefits
CSR: Small: Collaborative Research: Adaptive Applications and Architectures for Variation-Tolerant Systems
Numerous species are expected to modify their geographical range in response to climate change. Predicting the extent and speed with which such range changes will occur is difficult because we currently have a poor understanding of the mechanis
Maternal effects as a bridge between parental environment and offspring phenotype during range expansion
The wolves and moose of Isle Royale National Park, Michigan, have been studied for 50 years and represent the longest predator-prey study in the world. The project's objectives address three of the most fundamental questions in all of ecology:
LTREB RENEWAL:  The Population Ecology of Wolves and Moose on Isle Royale
Grasshopper populations, their enemies (predators and parasites), their food plants and nutrient availability for plants have been studied since 1982 in a Montana Palouse prairie ecosystem. Grasshoppers are the dominant herbivore in this ecosys
LTREB Renewal: Ecosystem Structure and Function in Palouse Grasslands
Many of the mineral resources necessary for modern society are found in the continental crust, particularly in the form of ores. Ore formation requires trace metals from the crust to be scavenged, redistributed and then re-deposited, processes
Quantifying the Role of Chemical Weathering on the Composition of the Continental Crust Using Mg Isotopes and Other Tracers
Collaborative Research: Estimating speciation/reticulation boundaries in asexual Alternaria: a genomics approach
Growing attention has turned to the importance of bridging more effectively from biodiversity-ecosystem functioning research to studies of the ongoing and potential consequences of actual species losses. The effects of non-random plant species
Biodiversity and ecosystem multifunctionality:   Do species loss order and richness matter in a native-dominated serpentine ecosystem?
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).How living systems integrate information in complex and changing environments is a central unsolved puzzle of biology. Plant form is continuously m
Combinatorial Control of Photomorphogenesis by Auxin and Brassinosteroids
Amphipods are common herbivorous crustaceans found in both marine and freshwater habitats. As a rule, all herbivores consume a restricted subset of available plants, and our ability to predict herbivore impacts on natural systems depends on und
RUI: SBBI: Phylogenetic effect on host use within generalist herbivores: a case study using marine amphipods in the family Ampithoidae (Crustacea: Amphipoda)
The principal investigator studies vertebrate brains and how they have evolved to subserve different behaviors and adaptations. In this project he will study the brain of the African lungfish, with various techniques that will reveal its struct
Organization of the Telencephalon in Lungfishes
This award is funded under the American Recovery and Reinvestments Act of 2009 (Public Law 111-5).    This research focuses on understanding the evolutionary history of the plant genus Artocarpus (Moraceae, mulberry family) with the goal of pro
REVSYS:  Phylogeny and Revision of Artocarpus(Moraceae) with a Focus on Understanding the Origins and Diversity of Cultivated Members of the Genus
The project will assess evolutionary relationships among tiger moths and the evolutionary associations of moth feeding behavior with plant chemicals that serve to protect moths from predators. Relationships among tiger moths will be assessed us
Phylogenetic and comparative studies of tiger moths (lepidoptera: noctuoidae)
Evolution typically leads to organisms that are increasingly complex in the way they look, the sorts of chemicals they produce, or the way their cells function. However, complex and costly characters can also be lost. For example, many lineages
Reduction and Reversal in the Funariaceae: Phylogenetic Perspective on Sporophyte Complexity and Role of the Calyptra
Award Title: Molecular mechanisms of ABA biosynthesis under drought stress Award descrition: Drought resulting from soil water deficit is one of the most common environmental factors that lead to substantial losses in productivity of crops worl
Molecular Mechanisms of ABA Biosynthesis under Drought Stress
The scaling of body parts is the quintessential feature of animal body form. Within species, organs need to be correctly proportioned to the body for the organism to function; larger individuals require larger hearts, longer limbs, etc., wherea
Collaborative Research: Tipping the Scales - A selection approach to the developmental regulation of morphological scaling
The objective of this research is to develop and apply efficient simulation methods to quantitatively describe complex biomolecular phenomena that usually occur in longer timescale than what conventional methods can achieve. Molecular recogniti
Achieving Long Timescale Sampling in Biomolecular Simulations
The grant from the Community Development Financial Institutions Fund supports Bridgeway Capital's lending to growing small businesses that will create and retain family-wage jobs for low-income households in western Pennsylvania.  These 'Growth
The $2 million ARRA Award was used to make business loans. The Northland Foundation deployed the entire $2 million in ARRA funds in the form of business loans to for-profit businesses and non-profit community organizations. The final $481,000 w
Opportunity Fund is a nonprofit, certified Community Development Financial Institution established in 1993. Opportunity Fund's mission is to advance the economic well-being of working people by helping them earn, save, and invest for the future
Development of Small Businesses, Affordable Housing, and Loan Loss Reserves
The purpose of this award is primarily to provide lending capital for small consumer loans in CACU's Target Market as explained in the CDFI certification and application process.  Our Target Market is African American consumers in Detroit Michi
Low/Moderate income consumer lending including affordable micro unsecured loans and auto lending which significantly increases accessibility (loan approval) and decreases the cost (rates/fees) to the target population.
Southeast Community Capital Corporation (SCC) received $2 million in Financial Assistance (FA) to expand its lending activity to include a rural retail financing initiative throughout the entire state of Tennessee with an emphasis on communitie
Southeast Community Capital Rural Retail Lending Initiative
FY 2009 CDFI Program Financial Assistance award for $600,000 supports BOC Capital Corp's (BCC) community development activities in its target market, in the following areas: (1) microloans and small business loans; (2) loan loss reserves, (3) c
FA Component, FY 2009 CDFI Program - to support activities in Financial Products; Financial Services; Development Services; Loan Loss Reserve, Capital Reserve or other uses supporting Comprehensive Business Plan; Operations.
Increase the number and dollar amount of loans to businesses and creat more jobs on the Pine Ridge Reservation.  Fourth quarter NACA 09 loans consisted of three credit builder loans totaling just over $6120 and 21 'Borrowed Bucks' loans totalin
Remaking Lakota Funds: Building our Loan Infrastructure
Mazaska was awarded a total of $870,153 to originate mortgages, home repair loans, and land loans; engage in strategic planning for 2010-2012; maintain two full-time positions; update the market study as part of the strategic planning process;
Mazaska Owecaso Otipi Financial, FA Component, NACA Program
SALT RIVER FINANCIAL SERVICES INSTITUTION
Salt River Financial Services Institution (SRFSI) received $730,000 in Financial Assistance and $139,786 in Technical Assistance.  The Financial Assistance is scheduled to be used as capital for SRFSI's Lending programs and/or Loan Loss Reserve
The ability to quantitatively predict RNA structures and stabilities is essential for understanding and rational design of RNA functions. Recent breathtaking new discoveries on the functions of non-coding RNAs have opened a new door for many po
Quantitative integration of stratigraphic and paleontological data derived from sedimentary rocks can enhance informative value of both the geological and fossil records. This approach will be applied to the depositional system (sedimentary bas
Stratigraphic Paleobiology of Marine Quaternary Successions of Po Plain, Italy
During normal animal development cells communicate with each other using signaling molecules. This ensures the correct body pattern is  made and key features such as limbs are properly formed. In this project, the fruit fly will be used as a mo
(ARRA) Analysis of epidermal growth factor receptor signaling in Drosphila
The majority of biological processes such as differentiation, growth, development and transformation are under tight control of cellular signaling systems. But detailed mechanisms of how cells decide when and where to execute these processes re
Systems Analysis of the Sporulation Initiation Network in the Bacterium Bacillus subtilis
This grant provides partial salary support for a laboratory technician for the University of Arizona Center for Environmental Physics and Mineralogy (CEPM) over a three year period. The (CEPM) houses analytical equipment for research in environ
Early Career: Technician Support for the University of Arizona Center for Environmental Physics and Mineralogy
Acquisition of an inductively-coupled plasma mass spectrometer
The award was to purchase a new FTIR spectrometer for use in the research laboratories of Marc Hirschmann and David Kohlstedt.
ACQUISITION OF A NEW MICROFTIR SPECTROMETER TO AID EXPERIMENTAL AND ANALYTICAL STUDIES OF C-H-O VOLATILES IN THE MANTLE
STTR Phase I: Development of Materials for Optical Band Gaps in Magneto-Photonic Crystals for Switching and Biosensor Applications
This project will lead to the development of low cost ultrafast lasers that can address lucrative emerging opportunities in the bioinstrumentation market.  Ultrafast lasers are finding commercial applications in areas ranging from corrective ey
STTR Phase 1: The Development of Quantum Dot Materials for Ultrafast Laser Applications
This Small Business Technology Transfer (STTR) Phase I project seeks to develop polyaniline nanofibers into a biologically responsive multi-functional material for use as a tool for the rapid and inexpensive diagnosis of urinary tract infection
STTR Phase I: Polyaniline Nanofiber Urinary Tract Infection Biosensor-A Multi-Functional Bioresponsive Material
This project aims to establish a multi-year collaboration between researchers at Drexel University in Philadelphia, Pennsylvania and the Czech Technical University (CTU) in Prague, Czech Republic. The technical foci of the collaboration is the
IRES;  U.S.-Czech Network Centric Intelligent System:  Drexel and Czech Technical University
To support the preservation of jobs that are threatened by declines in philanthropic and other support during the current economic downturn, as described in application A09-904255
Arts and the American Recovery & Reimbursement Act of 2009
CEDAR RAPIDS SYMPHONY ORCHESTRA ASSOCIATION INC
To support the preservation of jobs that are threatened by declines in philnathropic and other support during the current downturn.
Arts and the American Reinvestment & Recovery Act of  2009
Arts and the American Reocvery & Reinvestment Act of 2009
SOCIETY OF THE THIRD STREET MUSIC SCHOOL SETTLEMENT INC
MONTEREY COUNTY SYMPHONY ASSOCIATION, INC
To support the preservation of jobs that are threatened by declines in philanthropic and other support during the current economic downturn, as described in oour application (A09-906408) and the approved project budget.
Complex fluids are a broad class of materials that are usually homogeneous at the macroscopic scale and disordered at the microscopic scale, but possess structure at an intermediate scale (e.g., colloids, blood, and polymers). The rheology and
The Effects of Viscoelasticity on Filament Thinning %26 Drop Breakup in Microfluidic Devices: Single Molecule Experiments
The interaction of thermal radiation with nanofluids, which are nanoscale colloidal suspensions, has not been extensively examined. This research deals with fundamental thermal transport phenomena that occur when sufficiently intense thermal ra
Photothermal Energy Conversion in Nanofluids
To support the preservation of jobs that are threatened by declines in phanthropic and other support during the current economic downturn.
To support the preservation of jobs threatened by philanthropic decline and other support.
Arts and the American Recovery &Reinvestment Act of 2009
To support the preservation of jobs that are threatened by declines in philanthropic and other support during the currrent economic downturn.
This proposal will fund a petrographic microscopy system and an SEM-EDX upgrade for rapid sediment core characterization at the Lacustrine Core Facility. The SEM with EDX/EDS elemental analysis will be user friendly and table top to facilitate
Acquisition of SEM-EDX and upgrade of petrographic microscopy to enhance rapid sediment characterization at LacCore, the National Lacustrine Core Facility
The overall goal of the proposed research is to functionalize Si nanoparticles to target common cancers, enhance the nuclear magnetic resonance (NMR) signal of these particles using dynamic nuclear polarization (DNP), and characterize the hyper
Optical and Dynamic Nuclear Polarization Approaches to Hyperpolarization of Nanoparticles for Molecular Imaging
The cost of solar cells must be reduced by a factor of two in order to achieve grid parity. There are a number of new technologies which can achieve this goal, including advanced silicon, thin film (CdTe or CIGS), organic solar cells, or, in th
Multi-Scale Particle-Based Simulation of Disordered/Ordered Interfaces for High Efficiency Solar Cells
To support the preservation of jobs that are threatened by declines in philanthropic and other support during economic downturn.
to support the preservation of jobs that are threatened by declines in philanthropic and other support during the current economic downturn
To support the preservation of jobs that are threatened b declines in philanthropic and other support during the current economic downturn.
Arts and the American Recovery and Reinvestment Act 2009
To support the preservation of jobs that are threatened by declines in philanthropic and other support during the economic downturn, as described in application A09-905598 and the approved project budget.
The University of Texas Pan American URM program will engage undergraduate students from a Hispanic Serving Institution in cohort research and mentoring to increase the participation of underrepresented minorities in science. The URM program wi
URM: Undergraduate Research and Mentoring at a Hispanic Serving Institution Investigating a Rare Ecosystem
The project is a collaborative effort that exists to increase the number and effectiveness of high school mathematics teachers in the Cincinnati/Northern Kentucky region's urban core.
PRIME: Preparing Regional Increases in Mathematics Educators - A Robert Noyce Teacher Scholarship Program
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  Saint Joseph's University (SJU) is increasing the number of highly qualified math and science secondary school teachers who work in high-need sch
Enhancing the 5 YR Math and Science Education Programs at SJU
Arts and the American Recovery & Reinvestment Act of 2008
Need for the Study: The number of doctoral degrees earned in engineering increased from 3,166 in 1995 to 6,404 in 2005. While this overall increase is positive, growth in degrees awarded to international students (163% increase) significantly o
Factors that Facilitate or Inhibit Enrollment of Domestic Engineering PhD Students:  A Mixed Method Study
This engineering education research award to the University of Florida in collaboration with Virginia Commonwealth University will employ researchers to develop interactive virtual reality modules with haptic feedback to improve learning and pr
Collaborative Proposal:  Use of Haptics in a Virtual Reality Environment for Learaning of Nanotechnology
This engineering education research award to Texas Engineering Experiment Station will employ researchers to develop a novel sketch recognition-based learning system which will allow students to use freehand sketching to enter their drawings of
This engineering education research award to Arizona State University will undertake an experiment to evaluate active learning techniques and how such knowledge can be utilized to develop more effective classroom teaching for materials engineer
Using a Cognitive Framework of Differentiated Overt Learning Activities (DOLA) for Designing Effective Classroom Instruction in Materials Science and Nanotechnology
This is a collaborative project involving a consortium of six premier U.S universities and one national laboratory to train graduate students in an area of anticipated manpower need: advanced acceleration techniques. In particular, students wil
Collaborative Research: Graduate Student training through research on plasma-based particle accelerators
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).This research examines the history of emergent complexity in Northwest Alaska over the past 2000 years through a focused study of archaeological po
Doctoral Dissertation Improvement Grant: Late Prehistoric Socio-Economic Organization in Northwest Alaska: a Study of Pottery Production and Distribution in the Arctic
The objective of this EAGER project is to investigate the possibility of improving the mechanical properties of asphalt materials with the use of nonmetals separated from E-waste (e.g., computers, monitors, keyboard, cameras, TVs, etc.) and was
EAGER: Using Nonmetals Separated from E-Waste and Waste Plastic Bags in Improving the Mechanical Properties of Asphalt Materials
The Division of Chemistry supports Alon Gorodetsky of Columbia University as an American Competitiveness in Chemistry Fellow. Dr. Gorodetsky will develop chemically modified carbon nanotubes (with attached DNA) to be used in field effect transi
Electrical Detection of Protein Binding at DNA Modified Carbon Nanotube Field Effect Transistors
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  The Division of Chemistry supports Debraj Ghosh of the University of California - Santa Cruz as an American Competitiveness in Chemistry Fellow.
Novel Semiconductor-Metal Hybrid Nanostructures for Oxygen Electroreduction
Microbial habitats in extreme environments and organic transformations at ridge-crest hydrothermal systems are receiving increased attention as the novel properties of microbes that live in these environments become increasingly important in te
RIDGE: Tipping Points in the Evolution of Submarine Hydrothermal Systems: Habitat Generation, Organic Transformation, and Rock Alteration
Intellectual Merit:  The utilization of lignin as a resource for the production of biofuels is presently hampered by its resistance to chemical and biological manipulation, and consequently, by a lack of selective and cost-efficient processes f
EFRI-HyBi: Lignin Deconstruction for the Production of Liquid Fuels
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). This project will investigate the influence of weather and sea ice noise on polar climates using a modeling technique that has been applied extens
High-resolution climate modeling: The influence of weather and sea ice
'Wildfires cause great destruction including the loss of life and damage to property, infrastructure and the environment. The complexity of wildfire management arises from the uncertain dynamic interactions and dependencies among multiple syste
Collaborative Research: CDI-Type II--Integrated Weather and Wildfire Simulation and Optimization for Wildfire Management
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  Babesiosis is a rapidly emerging disease in the U.S., Europe, and Asia that is caused by infection with a protozoan parasite. The parasite, Babes
RAPID: Investigating a rapidly emerging epidemic of babesiosis in upstate New York
Mass spectrometry technology has the potential to revolutionize the biological sciences by enabling quantitative and comprehensive assessment of proteins (proteomics) and metabolites (metabolomics). A major challenge, however, is converting raw
CDI-Type II: MS-Omics Hub for Cyber-enabled Acceleration of Mass Spectrometry-based Metabolomics and Proteomics
Wildfires cause great destruction including the loss of life and damage to property, infrastructure and the environment. The complexity of wildfire management arises from the uncertain dynamic interactions and dependencies among multiple system
A few years ago, no one would have believed that a global team of volunteers could write a major operating system kernel or a comprehensive encyclopedia. But today, Linux and Wikipedia serve as evidence that loosely organized teams can create a
CDI-Type II: Open Sourcing the Design of Civil Infrastructure (OSD-CI)
Simplified ice sheet models in current use are incapable of accounting for the dynamics of flow transitions that are key to how ice sheets respond to environmental change. It is these regions that are now rapidly changing. The concern is that c
CDI-Type II: Dynamics of Ice Sheets: Advanced Simulation Models, Large-Scale Data Inversion, and Quantification of Uncertainty in Sea Level Rise Projections
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  Recent advances in imaging have enabled multimodal/multiscale observations of complex natural systems. Annotating, harvesting, extracting, and co
CDI-Type-II: Computational Challenges in the Discovery and Understanding of Complex Boiological Structures through Multimodal Imaging
CENTER FOR EXPLORATORY & PERCEPTUAL ART INC
BERKSHIRE ARTS & TECHNOLOGY CHARTER PUBLIC SCHOOL
The research objective of this award is to consider how people manage their attention in multi-cultural collaborations between geographically distributed individuals. “Virtual organizations”-- aggregations of individuals, facilities and res
VOSS: SUPPORTING INTERPERSONAL AWARENESS IN MULTICULTURAL VIRTUAL ORGANIZATIONS
This project will investigate a novel method for producing large amounts of high-quality DNA sequence data for phylogenomic applications. The project will extend a strategy called 'microarray-based genome selection' (MGS), which is capable of e
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). Project-based design organizing is fundamental to the contemporary relentless pursuit of innovation. Design organizations inevitably have virtual
VOSS-Collaborative Research: Virtualization of Work Capabilities in Project-Based Design Organizations
NORTHERN CALIFORNIA CHILD DEVELOPMENT INC
This award provides for ARRA Cost of Living  Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start and/or Early Head Start program. The purpose of the awa
ARRA COLA/QI- Head Start and Early Head Start
The purpose and expected outcomes of this contract are to recruit and maintain qualified staff, provide support staff in classrooms to lower the teacher/child ratio to provide more individualization for children with special needs. In addition,
The purpose of the Head Start Program is to promote school readiness and provide a comprehensive array of health, nutritional and social services to eligible three(3), four (4) and five (5) year old preschoolers and their families. The purpose
Awards a cost of living adjustment (COLA) increase of 1.85% in the amount of $13,627 for Early Head Start.  Staff salaries over a 12 month period.  Also, this action awards quality improvement funds of $32,422 for Early Head Start.
ARRA - QUALITY IMPROVEMENTARRA - COST OF LIVING ADJUSTMENT
Contract #0321 ARRA COLA & Contract #0322 QI
The Grant funds are used to increase base wages of Early Head Start staff to be competitive to salary within the Head Start field. These funds will allow us to attract and retain BA holders into teaching positions as to meet HS educational and
This award provides for ARRA Cost of Living Adjustment (COLA) and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) if the Head Start Act for the Early Head Start (EHS) program.  EHS promotes the school readiness o
ARRA Cost of Living Adjustment (COLA) and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start and/or Early Head Start Program. The Early Head Start program provides family -ce
INSTITUTE FOR HUMAN & SOCIAL DEVELOPMENT, INC
The ARRA Head Start Expansion funds provide funding to serve an additional 20 children at the East Palo Alto site located in East Palo Alto, San Mateo County, California. The goal of this grant is to provide enhanced center based services which
ARRA Head Start Expansion. This funding will be used to expand Head Start Services to 118 new families.  Two of the classrooms will be inclusion classrooms where special education staff will work with Head Start teaching staff to co-teach in th
Data resulting from our prior and current research, support the suggestion that the elmiric acids (EMA), which are carboxy containing analogs of the endocannabinoid anandamide, are potential anti-inflammatory agents (Burstein et al., 2007). It
The Elmiric Acids: Biologically Active Anandamide Analogs.
The program objectives address USPHS priority for Healthy People 2010, Focus Area 23, Building the public health infrastructure.  The program recruits and trains students to serve in defined shortage areas of epidemiology, environmental health
Currently the entire island of Maui is a dental HPSA, with a score of 16.  Approximately 32,000 Maui residents have no or limited dental insurance.  As of February 2008 the number of private dentists decreased 92 to 74.   Only two serve Medicai
Community Clinic of Maui New Dental Construction
NATIVE AMERICAN COMMUNITY HEALTH CENTER, INC.
NATIVE HEALTH was awarded $250,000 to utilize for Capital Improvements associated with the functions of the Agency Community Health Center Program.  The agency asked for and received funding to enable establishment of the Electronic Health Reco
Office of Assistant Secretary for Administration and Management
COUNCIL OF ATHABASCAN TRIBAL GOVERNMENTS
ARRA/CIP to renovate Arctic and Venetie Village Clinic.
The CIP proposal is comprised of three project types: renovation of two buildings and a certified electronic health record related purchase and implementation.  The electronic health record project will provide a critical element of the patient
BOUNDARY REGIONAL COMMUNITY HEALTH CENTER, INC.
BRCHC (Kaniksu Health Services) will build a new facility in Bonners Ferry, Idaho.  BRCHC owns the land and has invested approximately $70,000 in architectural designs.  When completed the BRCHC Bonners Ferry site will offer 9,029 square feet,
GREATER NEW BEDFORD COMMUNITY HEALTH CENTER,INC.
PMS/Interface Enhancement: Funds ($262,435) will be used to develop an integrated reporting system, e.g. the EHR, PMS, Billing, Dental, General Ledger, Payroll, Accounts Payable and ECAREware software. The Board and Administration need timely a
COMMUNITY HEALTH PARTNERSHIP OF ILLINOIS
With ARRA Capital Improvement Program funding for health centers, Community Health Partnership of Illinois (CHP) proposed to 1) purchase and implement an electronic health record system at one of our migrant health clinic sites (Mendota), 2) pu
Grant Name: Capital Improvement Program Purpose: To renovate space for on-site dental clinic Goals: Promote whole person care by bringing services to one site Importance: To expand and improve dental services through increased efficiencies and
JEFFERSON COMMUNITY HEALTH CARE CENTERS, INC
Jefferson Community Health Care Centers, Inc. (JCHCC), during the July 1, 2009 - September 30, 2009 reporting period, determined to make changes to how the organization will spend the allocated CIP awarded funds.  Originally, JCHCC planned to u
Stony Creek Community Health Center (SCCHC) has operated from a single site since 1989.  Through the ARRA  CIP grant, SCCHCs goals are (1) to enhance patient handicap access, (2) improve clinical diagnostics and patient outcomes, and (3) increa
The CIP funds encompass two projects. The first, a HIT/IT project, involved the selection and implementation of a practice management system and upgrading of server hardware to accommodate an aging IT infrastructure coupled with preparations fo
Grant awarded for IT/Equipment purchases only for the HCHN Burton facility.
Constuction of a new health center  The present health center is 4000 square foot. The new site will be a 6000 square foot health center designed to help alleviate the overcrowding. There is no room for expansion at present site and the site is
The award was given to enable renovation of a facility to expand services, implementation of EHR and up date of HIT - a CIP grant
SHACKELFORD COUNTY COMMUNITY RESOURCE CENTER
Title of Project:ARRA:Capital Improvement Program Purpose:The purpose of this Grant/Project is to purchase and implement a certified Electronic Health Record (EHR) system within the context of health outcomes.  List of Goals: Prior to 31 Decemb
The Upper Cumberland Primary Care Project proposes to use CIP funds to assist in building one new health clinic to replace an outdated and inefficient clinic site (Jackson County).  The new design will enhance patient flow, therefore improving
Project 1, dental van and equipment purchase:The ARRA CIP award funding for this project allows for the purchase and updating of patient-related equipment which is necessary for appropriate care and comfort of Center patients.   The award will
Funding from this grant award will also allow Hunter Health Clinic to upgrade clinical and non-clinical equipment at each of its four primary care clinics and its one mental health satellite clinic in Sedgwick County, Kansas.
There are three projects included as part of the CIP grant: 1) Walnut Street Renovation; 2) Electronic Health Records; and 3) Telephone Upgrade. 1) HHC's primary dental location at 1650 Walnut Street is in need of two facility improvements. A n
BROADER IMPACTS: Successful implementation of the project will result in novel nanostructure design tools accessible to a wide range of material scientists and macromolecular engineers. Student training on this project is multidisciplinary, req
Protein-protein recognition motifs basd on solenoid display
Dimension reduction plays an essential role in reducing the complexity of data so that the most useful information in data can be successfully extracted. Most existing dimension reduction methods are developed under the assumption that the data
New Statistical Methods for massive spatial temporal and Spatial Temporal process
The Nurse Faculty Loan Program provides funds for loans to MSN, DNP, and PhD nursing students being prepared to serve as faculty in schools of nursing.  All 2009 ARRA funds were disbursed.
The purpose of the Nurse Faculty Loan Program (NFLP) is to increase the number of qualified nursing faculty by providing loans to (full and part-time) students enrolled in an advanced education nursing program to prepare the loan recipients to
Award Title:  Characterization of a protein translocase in the pathogen Trichomonas vaginalis. Purpose of the research:  To identify and characterize members of a protein translocase in the hydrogenosome of Trichomonas vaginalis.  These studies
SHIFLETT:  CHARACTERIZATION OF A PROTEIN TRANSLOCASE IN THE PATHOGEN TRICHOMONAS VAGINALIS
This project is designed to 'close the loop' between outcome reporting and QI through the use of actionable data and targeted technical assistance resulting in improved immunization rates for children two years and under. The project will utili
ARRA- Health Information Technology Implementation
This award is part of the Recovery Act Health Center Cluster Program for the establishment of a New Access Point community health center (CHC).  This grant is funded through the Health Resources and Services Administration of the Department of
This award was made under the Increased Demand for Services opportunity.  It is to support the recall of four laid-off employees in addition to the salaries for two nurse practitioners, two nurse educators and two medical assistants.  These new
Health Center Integrated Services Development
This Increased Demand for Services (IDS) project will allow the Daily Planet HCH to enhance services to the urban homeless and underserved populations of the Greater Richmond Metropolitan Area, which is comprised of the city of Richm
SOUTHEAST LANCASTER HEALTH SERVICES, INC.
SouthEast Lancaster Health Services (SELHS) is an FQHC providing primary medical and dental care to the under served residents of Lancaster City and Lancaster County, PA.  SELHS received this ARRA Increased Demand for Services grant in order to
have now moved into an active status. Funding is being used to support increased access at the following geographic locations within the CVHS service area: Buckingham County, Petersburg, Hopewell/Prince George County, Fredericksburg, Farmville
Office of the Secretary of Health and Human Services
ARRA-Increase Services to Health Centers
UNIVERSITY MUSLIM MEDICAL ASSOCIATION, INC.
For more than 10 years, UMMA has served as a quality provider of low- and no-cost health care to some of the most medically indigent areas of South Los Angeles.  Our community is designated as both a Medically Underserved Area and a Primary Car
ARRA - Increase Services to Health Centers
16TH STREET COMMUNITY HEALTH CENTER, INC.
CIP funds will be utilized to address a series of unmet repairs, renovations, and equipment upgrades to enhance our ability to serve our patients.
ARRA - Increase Services to Health Centers funds will be used to provide additional healthcare clinic hours to the homeless population.The identified communities are Powell and Estill Counties, in Kentucky.  The current status of these communit
ARRA - Increase in Services to Health Centers
Grant name: Increased Demand for Services(IDS). Project's purpose/goals: to expand badly needed psychiatrist time with homeless patients suffering from mental illness and substance addictions at Worthington Street Shelter in Springfield; to inc
Springfield Dept. Health & Human Services, Health Services for the Homeless (SDHHS-HSH)
The purpose of this award is to expand access to needed primary health care services specifically by means of the following: We retained two (2) part time  pediatricians, one(1) part time practical nurse, one (1) part time pharmacist technician
ARRA / Increase Services to Health Centers
ARRA - Increase Services to Health Centers.  Purpose of funds: retain Medical Nurse Practitioner, Dental Hygienist, and Mental Health professionals in order to expand access and services. Funds are leveraged through the ramp-up period to the po
NORTH CENTRAL TEXAS COMMUNITY HEALTH CARE CENTER
The purpose of this award is to expand access to needed primary health care services specifically by expanding services at Community Healthcare Center's main clinic which is located in the heart of the city's medically underserved area. The IDS
PROVIDENCE COMMUNITY HEALTH CENTERS, INC., THE
Additional hours of operation with new staff hired will allow PCHC to meet the needs of our patients in the Providence area.
ARRA - Increase Services to Health Centers funds were used to preserve and restore the current level of services and staffing by (a) restoring work hours to hourly paid staff previously reduced by 5%, (b) restoring a 5% salary reduction to all
On March 27, 2009, Big Sandy Health Care (BSHC) received a Notice of Grant Award for an ARRA Increased Demand for Services grant. This award was made in response to BSHC?s application to increase service capacity at its Physicians for Women Cen
Title of Project:ARRA: Increase Services to Health Centers Purpose: The purpose of this Grant/Project is to increase the number of new patients treated for mental health-related conditions over a two-year period through increasing the number of
This Increased Demand Service grant will support the expansion of primary care, dental, and chiropractic services to low-income residents of Citrus County Florida.  Funds will primarily be used to augment existing services.  The goal is to incr
ARRA - Increase Services to Health Centers - Citrus County
Community Health Connection will hire a Family Practice Physician Assistant/Nurse Practitioner and a Medical Assistant 5-2009 creating two new jobs.  The new provider will see patients throughout the lifespan providing a primary medical home to
Offices of All Other Miscellaneous Health Practitioners
ARRA - Increase Services to Health Centers MNHC provides primary care services to San Francisco's predominantly low-income Latino community.  Census data shows that 102,168 persons live in the census tracts enclosed in MNHC's service area of wh
The Increased Demand for Services (IDS) grant project has impacted the need for health services by increasing health center staffing in Butler, Reynolds, Ripley and Wayne Counties in southern Missouri. The employment of an additional receptioni
The purpose of the ARRA- Increased Demand for Services (IDS) grant was to employ 1-FTE physician for our Cleveland Family Health Care Center to assist in the delivery of preventive and primary care services to the uninsured and underserved resi
ARRA - Increased Services to Health  Centers
Wasatch Homeless Health Care, Inc.'s ARRA IDS grant has helped retain the services of a full-time (1.0 FTE) physician assistant (PA-C) and a part-time (0.5 FTE) medial assistant. These positions will ensure that homeless Utahns will continue to
Hire one FNP and one FP.  Added on OBGYN.
Descriptive Title: “Understanding the mechanisms to correct the development of the immune system using stem cell therapy in children with inherited immune deficiency.” The central hypothesis of the Program is that the age of the hematopoiet
STEM CELL THERAPIES FOR PRIMARY IMMUNE DEFICIENCY
In previous work we created congenic strains carrying the DBA/2IBG (D2) region for alcohol preference on chromosome 2, on an otherwise C57BL/6IBG (B6) background. Recently, we have done the construction and testing of interval specific congenic
Study Gene for Alcoholism using Mouse Models
Identification of Genetic Modifiers of Anthrax Lethal Toxin Induced Pathophysiology Virulence of Bacillus anthracis is associated with production of a bipartite protein exotoxin called lethal toxin (LT). While our understanding of the in vitro
GENETICS MODIFIERS OF ANTHRAX LETHAL TOXIN INDUCED PATHOPHYSIOLOGY
AmeriCorps members tutor students in language arts, reading and math; recruit volunteers; provide employment and skills training and counseling; jobs placement; housing rehabilitation, weatherization and efficient energy services; and increase
RECOVERY New Jersey Commission on National and Community Service FORMULA PRIME
Recovery funds are going to support  12  AmeriCorps programs operating across the state of Texas. Eight of the eleven programs received funds to replace match resources that had been lost as a result of the economic crisis. The match replacemen
This award funds the approved ARRA AmeriCorps program and will assist the grantee in carrying out national service programs.  Corps members will assist local classroom teachers as classroom aids and recruit volunteers to carry out community pro
SOUTHEASTERN NETWORK OF YOUTH & FAMILY SERVICES INC
There is an increased number of runaway, homeless and street youth in need of services as a result of the economic crisis.  This National Direct AmeriCorps Recovery Act project aims to recruit 100 volunteers and match 15 AmeriCorps service memb
A. T. STILL UNIVERSITY OF HEALTH SCIENCES
This award funds the approved ARRA AmeriCorps AHEC Professional Corps Program.  AmeriCorps members are licensed, certified, or registered healthcare professionals who provide healthcare services in underserved areas and to underserved populatio
A.T. Still University of Health Sciences
All Other Miscellaneous Ambulatory Health Care Services
AmeriCorps members assist with recruiting volunteers and increasing services to clients at community based organizations in Northern New England.
Work on Forest Service Roads Salt Creek/Bear Canyon Campground Road- Trees trimmed along road way. Some of the existing asphalt road was removed, ground up and replaced. This work was also done in the Ponderosa campground. Culverts were also re
Forest Service Roads Project #CIM-0419-1
Repairs/Maintenance work - Clean & shape ditches and repair culverts on town highway #28, Bingo Rd
VISTA Recovery Program FY 2009: 6 AmeriCorps*VISTA members are placed throughout Wisconsin to work with UW-Colleges and small business owners to address the local economic needs, one VISTA member exited the program early.  These 6 VISTA volunte
Provide orientation training and ongoing distance learning support to over 3,000 ARRA-funded VISTA volunteers, supervisors and VISTA leaders, engaged in providing capacity building support to organizations helping low income individuals and com
VISTA Recovery Training and Technical Assistance Project
METROPOLITAN AREA ADVISORY COMMITTEE ON ANTI-POVERTY OF SAN DIEGO COUNTY INC
MAAC Project Head Start/ Early Head Start serves over 2,095 children in Full Day, Part Day, Home Base and Combination Option services in the cities of Carlsbad, Escondido, Fallbrook, Oceanside, Pauma, San Marcos, Valley Center and Vista all loc
RESOURCE CONNECTION OF AMADOR AND CALAVERAS COUNTIES, INCORPORATED, THE
Head Start and Early head Start COLA and Quality Improvement funds serving 240 children in Calaveras County. Head Start promotes the school readiness of low-income children through the provision of comprehensive health, developmental and family
Quality Improvement American Recovery and Reinvestment Act  The Long Beach Unified School District (LBUSD) Head Start and Early Head Start Program serves 2,181 low-income children and their families in the greater Long Beach area at 21 preschoo
The American Recovery and Reinvestment Act (ARRA) Cost of Living Adjustment (COLA) funds were awarded to upgrade contract Head Start employees into the County's retirement system and to provide a one-time COLA to the delegate agency. The ARRA Q
Name of Project: Head Start Head Start promotes the school readiness of low-income children through the provision of comprehensive health, developmental and family services. The program serves 7,759 children between the ages of 3-5 years.   Nam
ARRA Cola/QI: MEO Head Start received ARRA funding for Quality Improvements and COLA.  The number of children served is 298.  Program options include full and half day services.  The area served is Maui County, including Maui, Molokai and Lanai
Head Start/ Early Head Start ARRA COLA/QI
This award provides for a COLA increase for Head Start/Early Head Start staff and Quality Improvement Funding consistent with the provisions of Section 640 (a) (5) of the Head Start Act for Head Start/Early Head Start programs.
This award provided for ARRA Cost of Living Adjustment (COLA), and Quality Improvement funding consistent with the provisions of Section 640 (a)(5) of the Head Start Act. Head Start promotes the school readiness of low-income children through t
The ARRA funds for Quality Improvement are intended to be used to support various activities to improve the quality of the UCLA Early Head Start Program.
Early Head Start COLA and Quality Improvement. Awards cost of living adjustment and program quality improvement funds
This award provides ARRA funds for the addition of Head Start part-day classroom services to two groups of children, with eighteen children in each classroom.  Services are provided in Tucson, AZ and Rio Rico, AZ. This award also provides servi
This project expands SETA's Head Start program by providing funding of $2,068,866 to serve an additional 150 students utilizing the grantee and 5 delegate agencies. The Head Start program provides family-centered educational services for low-in
CHILD DEVELOPMENT RESOURCES OF VENTURA COUNTY, INC.
The Expansion program is already serving 50 children in a center base option and 4 in a family child care option.  Twenty (20) of these children are being served through a full-day/full-year program and 30 of these children will be served throu
Head Start Expansion is awarded for the purpose of expanding the number of Head Start slots served by the grantee.  The City was awarded second year funds to serve 100 additional children in its Head Start program.
The ARRA funding created an additional 60 full-day, full year Head Start slots housed in both the northern and southern parts of the Acelero Learning Clark County?s current service area, with extended day services available for families that ar
Waterman Clinic Expansion Project  Covenant Community Care leases space from Southwest Counseling Solutions, a community mental health center in southwest Detroit. The clinic space CCC leases currently is accessed through the exterior (street l
ARRA - Capital Improvement Program The objectives of Marana Health Center, Inc. with this project is twofold: to replace and/or upgrade some of our current information technology network hardware and IT equipment in order to increase the speed
Renovation and expansion of Bluegrass Community Health Center's Versailles Road Clinic.  Provide funding for purchase of a new practice management system and electronic medical records.
ARRA-Capital Improvement Program (Integrated Electronic Health Record)  To upgrade our IEHR system.
Health Care Equipment & Supplies Provision
The Capital Improvement Grant(CIP) award was to complete the build out of RMMAB, in particular, an estimated 8,400 square feet located in the building's lower level to support the operations associated with our Patient Navigation Program (PNP),
EAST BOSTON NEIGHBORHOOD HEALTH CENTER CORPORATION
The East Boston Neighborhood Health Center (EBNHC) CIP project will ensure that the East Boston community has access to high quality medical care, particularly diagnostic services that are vital for disease prevention and the identification of
RICHLAND COMMUNITY HEALTH CARE ASSOCIATION
Program Name:  01-RCHCA-CIP IT / Equipment - In this program, Richland Community Health Care Association, Inc. will purchase IT software and hardware, medical equipment, and furiture needed by the medical facilities.
Capital Improvement in Health Center Facilities:  Project #1--Keystone proposes to construct a 2624 square feet addition to the 820 Fifth Avenue site and make some renovations.  This additional space will house four rooms for providers to see p
Capital Improvement Program - to build a new clinic in Fort Morgan to meet the health care needs of a rural community with a need for access to affordable, quality health care. Grant Name: ARRA- Capital Improvement Program. Purpose: Constructio
ARRA - Capital Improvement Program (CIP):  Funds made available by the Recovery Act will support this health center to expand its capacity to provide primary and preventive health care services to medically underserved populations of metro-Atla
CENTRO DE SALUD COMUNAL DR JOSE S BELAVAL, INC
HPM Foundation (Formely Junta del Centro Comunal de Salud Dr. Jose S. Belaval or Belaval Health Center) received in 6/25/09 an ARRA Capital Improvement Award of $ 645,325.00 to expand, update and centralize its existing practice management and
The purpose of the award is for a New Facility completion project to increase access to health care, to improve the community?s health status.  Still located on the Kodiak Island Borough Providence Medical Campus, this facility allowed KCHC to
The Capital Improvement Program grant award ($382,685) allows funding for our three projects which featured repairs and alterations to the Clay-Battelle Community Health Center (new roof, paving of our parking lot, replacement of old computer e
The purpose of this expansion is to respond to the increased need of community residents with limited access to health care for life-long health.
The CIP funds allow Edward M. Kennedy Community Health Center to renovate approximately 4,600 SF to provide additional medical and mental health rooms so that new providers hired under IDS can have space in which to see new patients.  The Healt
ARRA - Capital Improvement Program:  Wayne Memorial Community Health Centers (WMCHC)proposes to use the CIP funds allocated in three initiatives. One large and one small renovation project represent the first phase designed to promote the susta
This Capital Improvement Grant supports information technology enhancements and a security system  The goal is to increase clinic capability and efficiency and therefore increase the quality of health care provided and the number of patients th
ARRA - Capital Improvement Program - Gulf County
ARRA Capital Improvement Grant The CIP funds are for a new facility for our main site. The facility will increase our square footage by 7000 square feet. This will allow us to have space for dental, pharmacy, xray and mental health in house. Cu
Capital Improvement Project - Palm Beach County Health Services  This grant will support renovations to multiple primary health care clinics in Palm Beach County; support the installation of hurricane doors at three sites; and support the insta
ARRA - Capital Improvement Program - Palm Beach County
This Capital Improvement Grant is supporting information technology enhancements for the purpose of increasing the efficiency and capacity of health center operations.  The goal of these enhancements is to allow the health center to serve more
ARRA - Capital Improvement Program - Hernando County
The Capital Improvement Project funding is being utilized to provide needed renovations for the Tallulah site location of Outpatient Medical Center, Inc. This project funding will also be used to implement Electronic Health Records(EHR)througho
The purpose of the Capital Improvement Grant was two fold: first, to replace or purchase some much needed equipment and secondly to purchse  the equipment to ready us for EHRs. Goals: (1)to replace two air conditioning units on the roof of the
This award was to provide for Capital Improvement to our Health Center via the renovation of the existing building, and via the purchase of new computer equipment.  We hope with this infusion of capital, we can provide more healthcare to the co
Three projects were submitted under the Capital Improvement ARRA opportunity.  The first project - Mobile Medical Unit Replacement and Update/Purchase of Medical Equipment and Operational Infrastructure ($150,524) provides the balance of needed
HENDERSON COUNTY RURAL HEALTH CENTER, INC.
The purpose of this award is to carryout 3 health center capital improvement projects: 1) Dental Expansion; 2) Replace and upgrade outdated equipment and 3) Implement E-Prescribing.
GREATER PHILADELPHIA HEALTH ACTION, INCORPORATED
The CIP will provide GPHA with the ability to upgrade and renovate patient waiting and examination areas.  Also implementation of an electronic health record (EHR) will accommodate improved evaluation of patient outcomes, in real time, and will
HRSA has provided Syracuse Community Health Center with an approval to utilize CIP funds to purchase equipment and to perform minor renovations at approved sites of SCHC. A new CIP application has been submitted to HRSA and we received notifica
ARRA - CAPITAL IMPROVEMENT PROGRAM OF SYRACUSE COMMUNITY HEALTH CENTER, INC.
The CIP funds will be used to construct a new healthcare clinic in Powell County ('Foothills Health and Wellness Center') that will serve homeless people. The HCH program is currently operated from a 40' mobile health clinic traveling between P
ST JAMES SANTEE FAMILY HEALTH CENTER INC
The CIP will provide funds for the renovation of over 6,992 sq. ft. of space at one of our properties, a former elementary school building,into a medical facility. Once the renovated building is completed we will relocate the present satellite
GREATER LAWRENCE FAMILY HEALTH CENTER INC
North Site Expansion and Renovation Project
Nurse Faculty Loan Program-ARRA. Funds are to be used to provide loans to students enrolled in Master of Science in Nursing Program's Nursing Education track. The goal of the project is to enhance the number of MSN students preparing to teach n
ARRA - Nurse Faculty Loan Program.  The purpose of the grant was to provide funding for the establishment of a revolving nurse faculty loan fund that would enable eligible candidates with an interest in teaching nursing courses achieve the appr
Both healthy and pathological aging entail some degree of cognitive and neural decline. Executive functions appear to be particularly affected by aging (Hasher and Zacks, 1988). Executive function has traditionally been associated most strongly
Top-Down Modulation and interactions between perceptual and reflective processes
MicroRNAs (miRNAs) constitute a novel class of gene regulatory elements with important roles in the control of gene expression and development in plants and animals. miRNAs are endogenous, small non-coding RNAs which inhibit gene expression by
The award is a Ruth L. Kirschstein National Research Service Award Individual Postdoctoral Fellowship.  The title of the work is 'Genomic Variability of Cytomegalovirus in a Clinical Setting'.   The purpose of the fellowship is develop a better
Genomic Variability of Cytomegalovirus in a Clinical Setting
This award is for the Health Information Technology Implementation grant.  The goal of this project is to install an electronic medical record system in the eight health centers in Iowa and Nebraska. By achieving this goal, we will enable the c
ARRA - New Acess Point for Health Center Cluster Program
ELLIS COUNTY COALITION FOR HEALTH OPTIONS
The award/grand name was New Access Point (NAP).  The grant was ascertained to provide the fiscal assistance in the providing of comprehensive health care services in the targeted population of Ellis County and surrounding communities.  The pri
Recovery Act Health Center Cluster Program
Offices of Physicians, Mental Health Specialists
Increased Demand for Services - This award will fund additional staffing to expand our existing primary medical and dental care services. CommuniCare Health Centers will hire a full time family practice physician and a part-time physician assis
This award provides funds to conduct workshops aimed at improving the broader impacts efforts of scientists. Through professional development workshops, scientist-graduate student teams will produce interactive materials based on the ?Ocean Lit
Collaborative Research: Linking Researchers and Graduate Students through COSEE Tools & Services
Teachers are Key addresses a central aspect of the crisis in computer science (CS) education: the need for quality high school CS teachers and how to build effective supports and professional development system at a local and national level for
TEACHERS ARE KEY: PARTNERING WITH AND SUPPORTING QUALITY HIGH SCHOOL COMPUTER SCIENCE TEACHERS WITHIN THE SECOND LARGEST SCHOOL DISTRICT IN THE COUNTR
This proposal will be awarded using funds made available by the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). The proposal requests numerous Shipboard Scientific Support (SSSE) items for the vessels operated by the Universi
Shipboard Scientific Support Equipment Enhancements 2009
In the nematode C. elegans, experimentally introduced double-stranded RNA (dsRNA) mediates specific gene silencing that spreads between cells and tissues of the animal (and can even be transmitted to progeny). This remarkable spreading phenomen
EAGER:  Stress resistance pathways in C. elegans
To support the preservation of jobs that are threatened by declines in philanthropic and other support during the current economic downturn, as described in application A09-904547 and the approved project budget.
Arts  and the American Recovery & Reinvestment Act of 2009
To support the preservation of jobs that are threatened by declines in philanthropic and other support during the current economic downturn, as described in our application (A09-905021).
To support the preservation of jobs that are threatened by declines in philanthropic and other support during the current economic downturn, as described in the application (A09-905036) and the approved project budget.
The Arts and the American Recovery and Reinvestment Act of 2009, Public Law 111-5
This proposal is a request to support Graduate Research Fellowships
To support the preservation of jobs that are threatened by declines in philanthropic giving and other support during the current economic downturn.
Project Abstract: The Gleason Controlled Burn, to be conducted near Ely, Nevada, provides an opportunity to quantify the effects of fire on soil structure, and to test hypotheses on how fire-induced changes in soil structure can lead to coupled
Fire-Induced Changes of Soil Structure: Implications for Soil Hydraulic Properties and Coupled Erosion by Water and Wind
The objective of this research is to investigate novel architectures for the realization of ultra-low-power, integrated, pulse-based, ultra-wideband radar and imaging sensors. The approach is to exploit compressive sensing for high-speed baseba
Ultra-wideband mmWave Radar and Imaging Sensors based on Compressive Sensing
I - 95 Resurfacing from the Ct State Line to Exit 3, C-1
MASSACHUSETTS MUSEUM OF CONTEMPORARY ART FOUNDATION, INC.
Support for preservation of jobs threatened by declines in philanthropic and other support during the current economic downturn.
THE POINT Community Development Corporation
TRADITIONAL ARTS IN UPSTATE NEW YORK INC
NATIONAL NETWORK FOR FOLK ARTS AND EDUCATION, THE
ARTS AND THE AMERICAN RECOVERY AND REINVESTMENT ACT
To support arts projects which preserve jobs in the nonprofit arts sector threatened by declines in philanthropic and other support during the current economic downturn
Arts and the American Rcovery & Reinvestment Act of 2009
NEW ENGLAND FOUNDATION FOR THE ARTS, INCORPORATED
To support the preservation of jobs that are threatened by declines in philanthropic and other support during the current economic downturn as described in application (A09903885) and the approved project budget.
BALTIMORE OFFICE OF PROMOTION AND THE ARTS
FLUSHING COUNCIL ON CULTURE AND THE ARTS INC
Under the American Recovery and Reinvestment Act of 2009 to provide grants to States to support nutrition services including nutritious meals, nutrition education and other appropriate nutrition services for older Americans in order to maintain
ARRA OAA Home-Delivered Nutrition Services
Provides additional funding to Area Agencies on Aging for Elderly Nutrition Home Delivered Meals Programs to feed seniors in need and to restore nutrition services and local food service positions eliminated due to cost increses and funding los
Congregate Meals - ARRA this is for the Elderly population 60 years and over including the at-risk population.  These meals are provided at a congregate nutrition site throughout the State of Colorado.
Home-Delivered Meals - ARRA - this is for the Elderly population 60 years and over including the at-risk population.  These home delivered meals will be distributed throughout the State of Colorado.
SOCIAL SERVICES, CONNECTICUT DEPARTMENT OF
HEALTH AND SOCIAL SERVICES, DELAWARE DEPT OF
ARRA provided funding for Congregate Nutrition Services. Established in 1972 under the Older Americans Act, the program provides meals to older Americans in congregate facilities such as senior centers, adult day centers and faith-based setting
PUBLIC HEALTH AND HUMAN SERVICES, MONTANA DEPARTMENT OF
The Adminstration of Aging has made additional funding available for congregate meals. These funds support community programs that provide nutritious meals to individuals age 60 andolder at congregate settings (e.g., senior centers, churches).
ARRA Congregate Nutrition Services (2009 T3C1_ARRA)
American Recovery and Reinvestment Act of 2009 Grant for Congregate Nutrition Services.  The grant is being used to stablilize State and local government budgets, in order to minimize and avoid reductions in essential services and counterproduc
ARRA of 2009 Grant for Congregate Nutrition Services
AGING & DISABILITY SERVICES, TEXAS DEPARTMENT OF
Meals served in Senior Centers that provide 1/3 of a senior's daily nutritional requirements
HEALTH AND HUMAN RESOURCES, VIRGINIA SECRETARY OF
ARRA provided funding for Home-Delivered Nutrition Services.  Established in 1978 under the Older Americans Act, the program provides meals to seniors who are home-bound.
HEALTH SERVICES, WISCONSIN DEPARTMENT OF
Nutrition services for elderly -- home delivered meals:  Provided nutrition services to elderly, including home delivered meals.  Funding was distributed to local, county and tribal agencies by Area  Agencies on Aging .  The local offices contr
ARRA Forest Fuels Reduction, Jobs and Biomass Utilization.  This grant enables the Wallowa-Whitman National Forest to mechanically thin overstocked forest stands that fall with in the Wallowa County (OR) Community Wildfire Protection Plan.  Ben
Native American Housing Block Grant, Competitive - NAHASDA eligible activiites including new construction of 2 homes in Sand Point Alaska; and rehabilitation for accessibility site improvement to 15 homes in Unalaska Alaska.
Native American Housing Block Grant, competitive - NAHASDA-eligible activities including acquisition, new construction, rehabilitation of affordable housing site improvement, development and rehabilitation of utilities and infrastructure, utili
Rehabilitation, Replacement and New Construction
Nativem American Housing Block Grant(Competitive) Recovery Act Funded,Cunstruction of 13 new Single family homes for low income Native american Families.
Construction of 13 new homeownership Units
Soil, sediment and subsurface environments harbor a tremendous diversity of microbes, and a major research goal is to better understand how such complex systems evolve, function, and respond to environmental changes. The reductionist approaches
ARRA: MSB: INSIGHTS INTO MUTUALISTIC INTERACTIONS BETWEEN FREE-LIVING, PLEOMORPHIC SPIROCHETES(FLIPS) AND OBLIGATE DECHLORINATORS (DEHALOCOCCOIDES)
Bacterial species are poorly understood both in an evolutionary and taxonomic sense.  Recently, through developments in DNA sequencing, the genus Halorubrum has emerged as an excellent model for testing hypotheses regarding the nature of bacter
Toward Comprehending Prokaryotic Species Using Halorubrum sp. as a Model
Many organisms exhibit a remarkable capacity for tissue regeneration. Most dramatic is the ability of free-living flatworms known as planarians to regenerate an entire new body plan from small excised pieces of tissue. This regenerative ability
Molecular and Cellular Biology of Voltage-operated Ca2+ Entry in Planaria
FRESNO COMMUNITY DEVELOPMENT FINANCIAL INSTITUTION
The Fresno Community Development Financial Institution (Fresno CDFI) is utilizing the Financial Assistance (FA) grant from the CDFI Fund to administer and capitalize a revolving loan fund for financing micro- and small-businesses, which will re
CAPE & ISLANDS COMMUNITY DEVELOPMENT INCORPORATED
Community Development Financial Institution grant to expand the capacity of financial institutions to serve populations and communities lacking adequate access to financial products and financial services.
Community Development Financial Institution Financial Assistance Award to provide small business loans to underserved markets.
NEW MEXICO COMMUNITY CAPITAL MANAGEMENT, LLC
New Mexico Community Capital (NMCC) will use the requested grant award towards our second fund, including, the development of structure, strategy and approaches for that fund.  We would also like to be able to use the funding for initial capita
New Mexico Community Capital Funds I & II
CDFI Fund financial assistance award.  The award will be used to increase the Atlanta Micro Fund's capacity to provide small business loans and business management assistance to entrepreneurs starting or expanding businesses in metropolitan Atl
Small Business Loan and Technical Assistance Program
Mendo Lake Credit Union (MLCU) is a community chartered credit union and certified CDFI established in 1959 that serves the communities of Mendocino and Lake County in rural Northern California, specializing in low-cost auto and manufactured ho
Lending Capital to Support Affordable Housing and Auto lending products (FA Component, CDFI Program)
WESTERN MASSACHUSETTS ENTERPRISE FUND, INC., THE
This award is a capital grant under the U.S. Department of the Treasury Community Development Financial Institutions Fund Program.  It was used to make loans to further economic development in Western Massachusetts.
Providing financial and technical assistance to businesses in Western Massachusetts
The $1.9 million award has primarily created a loan pool for pre-development purposes for nonprofit organizations. Organizations will use these loans for reasons including (but are not limited to) environmental assessments; architectural, engin
Native American Community Development Financial Institution (CDFI) Assistance 2009 Grant- $730,000 - Financial Assistance: Financial Assistance will be used to provide credit to businesses that have difficulty obtaining loans from traditional b
Four Directions Development Corporation (FDDC), a Native Community Development Financial Institution (CDFI) established in 2001, provides housing and business loans to Maine's four Native American tribes - Penobscot, Passamaquoddy, Maliseet and
Native American CDFI Assistance (NACA)  Program 2009  -  FDDC Strategic Restructuring Initiative
Intellectual merit. In order for multicellular organisms to function properly, individual cells within the organism must be able to share information. One way this can happen in plants is through the directed transport of transcription factors
Identification of the mechanisms of protein transport during Arabidopsis root development
Scientists are just beginning to discover the extent to which fluorescence occurs in organisms in nature, and what roles fluorescence may play in influencing an organism's survival. Our knowledge has been limited in part because humans can see
Spider Fluorescence as a Potential Visual Signal
NSF Proposal DMS-0920850 'Novel mathematical methods for retrieving mechanical properties and microstructural information of cancellous bones'.
NSF Collaborative Rsch: Novel Mathematical methods for retrieving mechanical properties and microstructural information of cancellous bone.
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).   This project will develop mathematical models to study the influence of subcellular architecture on the dynamics of gene expression and regulati
Multiscale Modeling of Subcellular Structure and its Effects on Gene Expression and Regulation
Does the 'gendering' of constitutions promote women's equality? New democracies, and some older ones, increasingly include gender provisions in their constitutions. This research examines the incorporation of gender in national constitutions an
Collaborative Research: Gender and Constitutions: A Comparative Analysis of the Effect of Gender Provisions
The goal of this project is to explore the link between public demand for and elected officials? supply of efficient, responsive government. In particular, it examines three distinct mechanisms for mobilizing grassroots pressure for good govern
Doctoral Dissertation Research in Political Science: When Do Citizens Grasp the Purse Strings? Budget Transparency and Political Engagement in Indonesia
Protocols for conducting forensic interviews of children should be informed by research, but interviewers who obtain evidence from alleged victims of abuse frequently use unreaserched techniques. This project examines two popular procedures: cu
Collabortative Research:The Impact of Cuing and Comfort Drawing on the Eyewitness Testimony of Behaviorally Inhibited and Uninhibited Children
This proposal addresses a compelling contemporary question in human biology: How do development and energetics determine the pace and trajectory of reproductive maturation? This project takes advantage of a unique opportunity in The Gambia to d
Energetic, Development, and Ovarian Function in Adolescent Gambian Women
The purpose of this research is to test a set of interrelated hypotheses about the psychosocial benefits of racial/ethnic diversity in urban middle schools.  It is hypothesized that greater diversity can benefit students' mental health, intergr
PSYCHOSOCIAL BENEFITS OF ETHINIC DIVERSITY IN URBAN MIDDLE SCHOOLS
Our team of undergraduate coders has completed all of the coding. We have conducted two inter rater reliability analysis, and I have submitted the final report to the National Science Foundation. The grant was a success and we will be cleaning
Treaties, Institutions & Torture: Theoretical and Empirical Inquiry
Pepperdine University has acquired a Cell Lab Quanta SC Flow Cytometer system. The flow cytometer instrument will be utilized in our summer undergraduate research programs and Honor's research program in original, student generated research pro
MRI: Acquisition of a Flow Cytometer Instrument for Undergraduate Research
MRI: Acquisition of a 400 MHz NMR Spectrometer
A calibration of the paleosol carbonate CO2 barometer is proposed in order to improve estimates of the concentration of CO2 in Earth?s ancient atmosphere. The concentration of CO2 in the soil during soil carbonate formation, S(z), is required i
Collaborative Research: Calibrating the paleosol carbonate CO2 barometer for vertic paleosols by monitoring soil CO2 in modern Vertisols
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  Leslie E. Sieburth IOS 0922288 BYPASS1 root-to-shoot signaling: the mobile signal interacts with the auxin pathway    Plants develop in an integr
BYPASS1 ROOT-TO-SHOOT SIGNALING: THE MOBILE SIGNAL INTERACTS WITH THE AUXIN PATHWAY
It is widely acknowledged that making decisions often involves the consideration of both 'rational' and 'intuitive' inputs. This program of research will examine how people decide the amount of weight to assign rational considerations and intui
UNDERSTANDING DECISIONS TO CHOOSE INTUITIVELY OR RATIONALLY
Regulation of meristem function by AIL proteins Project Summary The aerial portion of a plant is derived from a small group of cells at the apex of the plant called the shoot apical meristem. The shoot apical meristem is responsible for continu
Regulation of meristem function by AIL proteins
This National Science Foundation award through the Major Research Instrumentation program will allow the purchase of a 400 MHz NMR spectrometer that will enhance Whitman College?s faculty and undergraduate research and research training program
MRI: Acquisition of a 400 MHz NMR spectrometer for undergraduate research and research training
During higher plant embryogenesis, the single celled zygote proliferates and differentiates to form the mature embryo within the seed. During this phase of the life cycle, not only must the plant body form (called morphogenesis) but also stora
Transcriptional Regulatory Networks Controlling Higher Plant Embryogenesis
With this award from the Major Research Instrumentation (MRI) program, Professor Arne Gericke and his colleague Edgar A. Kooijman will acquire a surface plasmon resonance (SPR) instrument. The research uses include projects aimed at studying: 1
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  Funds from this grant will support the acquisition of a variable pressure sample chamber scanning electron microscope (VP-SEM) equipped with cath
MRI: Acquisition of a Variable Pressure Scanning Electron Microscope for Materials Characterization in Multidisciplinary Research and Training
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). The primary scientific goal of the project is to upgrade the capabilities of the LHCb experiment at the CERN LHC. It will enable the experiment to
MRI: Development of Hybrid Pixel Modules for the LHCb Upgrade
The objective of this project is to acquire an electron-beam lithography system for the University of Michigan. This system will be used to facilitate research on a broad array of new technology, materials, structures, and devices, including n
MRI: Acquisition of an Ultrahigh Resolution Electron-Beam Lithography System for the University of Michigan Lurie Nanofabrication Facility
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  This major research instrumentation (MRI) award funds the purchase of a confocal system to support the research programs of 11 Biological Science
MRI: Acquisition of a Nikon A1R Confocal Microscope
Experiments with rare isotope beams are critical for advancing our understanding of the nuclear force and nuclear structure. Improved knowledge of nuclei will allow questions concerning the nature of neutron stars and dense nuclear matter, the
MRI: Development of an Active Target Time Projection Chamber to Study Reactions Induced by Exotic Beams
Researchers at the University of Texas at Austin are requesting the purchase of a cutting-edge time-of-flight secondary ion mass spectrometer (TOF-SIMS) for spectroscopy, imaging, and sputter depth profiling of a large variety of solid samples.
MRI: Acquisition of a Time-of-Flight Secondary Ion Mass Spectrometer
The Biology Department Microscopy Facility at Central Michigan University will acquire a Laser Scanning Confocal Microscope with this award from the Major Research instrumentation program. The new instrument will have increased sensitivity, res
MRI: Acquisition of a Confocal Microscope for Multi-disciplinary and Teaching in the Central Michigan University Multi-user Microscopy Facility
Funding is requested to develop a unique high-pulse-energy (~1 J/pulse) laser system that will enable quantitative ultra-high-frame-rate ( > 20 kHz) Particle Imaging Velocimetry (PIV), Planar Laser-Induced Fluorescence (PLIF) and Rayleigh and R
(ARRA) MRI: Development of a High Energy, High-Repetition-Rate Laser Diagnostic System for Time-Resolved Investigations of Turbulent Combustion Processes
This project, developing a world-class interactive large-field-of-view 95 megapixel immersive virtual-reality environment, aims at creating a novel, demonstrably useful, rich, and expressive interaction, visualization, and analysis that truly l
MRI: Development of a Next-Generation Interactive Virtual-Reality Display Environment for Science
We propose to development a novel NMR/optical instrument that combines the techniques of optically-pumped (OPNMR) and optically-detected NMR (ODNMR) spectroscopy.  Once completed, this instrument will allow us to study questions of a fundamenta
MRI:DEVELOPMENT OF COMBINED OPTICALLY-PUMPED & OPTICALLY-DETECTED NMR OF BULK & NANOSTRUCTURED SEMIC
Major Research Instrumentation MRI: Acquisition of Advanced Scientific GPS Receivers for Magnetospheric and Ionispheric Research
MRI: Acquisition of Advanced Scientific GPS Receivers for Magnetospheric and Ionospheric Research
This project will develop a real-time, sensitive sensor for measurement of atmospheric mercury (Hg) to resolve uncertainties in atmospheric Hg measurements imposed by low temporal resolution of current sensors. Based on a laboratory prototype H
MRI: Development of a Cavity Ring-Down Sensor for Real-Time Measurement of Atmospheric Mercury Concentrations and Fluxes
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). The goal of this project is to create an inductively coupled plasma mass spectrometry (ICP-MS) facility with capabilities to study trace elemental
MRI ACQUISITION:  AN ICP-MS FACILITY AT THE UNIVERSITY OF UTAH
This project will develop a novel chemical ionization aerosol time-of-flight mass spectrometer (CI-ATOFMS) that will couple the soft and selective ionization of CI, the ion trapping and transfer properties of an electrodynamic ion funnel (IF),
MRI: Development of a Chemical Ionization Time-of-Flight Mass Spectrometer for On-line Organic Aerosol Analysis
Animal behavior ultimately determines survival and reproduction of individuals. In social species, behavior occurs within groups where the choices made by an individual is influenced by and influences others. Animals in groups communicate sophi
The neural and hormonal substrates of communication in a social environment: Signalerand bystander effects
This Small Business Innovation Research (SBIR) Phase II project involves the examination of consumer consumption behavior across multiple on-line domains to predict those items to be most likely consumed in the next interchange and the terms un
SBIR Phase II: Predicting Behavior in Electronic Commerce Environments
Shifts in gene expression drive differentiation of tissues and the evolution of new morphologies in multicellular organisms. However, studies linking the evolution of gene expression and the evolution of development are difficult in complex org
Collaborative Research: The evolution of gene expression underlying fruiting body development in fungi
Large DNA viruses, bacterial viruses ('bacteriophages' or 'phages') and eukaryotic viruses such as herpes viruses, package the viral genome inside a protein shell (capsid). The bacteriophage T4, which infects E. coli, packages a 171-kb 56 micro
Mechanism of ATP-driven DNA Packaging in Bacteriophage T4
COLLABORATIVE RESEARCHPOPULATION RESPONSE TO QUATERNARY ENVIRONMENTAL CHANGE: GREAT BASIN LAGOMORPHS AS A CASE STUDYElizabeth A. Hadly, Department of Biology, Stanford UniversityDonald Grayson, Department of Anthropology, University of Washingt
COLLABORATIVE RESEARCH: POPULATION RESPONSE TO QUATERNARY ENVIRONMENTAL CHANGE: GREAT BASIN LAGOMORPHS AS A CASE STUDY
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  This Small Business Innovative Research (SBIR) Phase II project will address material innovations required to successfully take spin-transfer tor
SBIR Phase II: Dual Magnetic Tunnel Junction (DMTJ) Materials and Structures for STT-RAM
This Small Business Technology Transfer Phase II project will commercialize laser vapor deposition (LVD™), an innovative technology for depositing thin films and hetero-structures of functional polymers, functionalized nanoparticles and nanop
STTR Phase II:   Laser Vapor Deposition for thin film functional polymers and nanocomposites
This Small Business Innovation Research (SBIR) Phase II proposal is for the development of extremely high energy density capacitors based on the spin-on metal oxide dielectric and conductor technology developed in Phase I combined with very hig
Epitaxial Metal Oxide Thin Films using a novel Polymer Assisted Deposition (PAD) Technique.
This SBIR Phase II project will provide technology to perform remote nucleic acid testing (NAT) in any location. The combination of (a) our Probe-Target-Reporter (PTR) assay which allows the detection of unlabeled Target DNA, (b) our Parallume
Hybridization and SNP Detection Using Unlabeled Target DNA
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public law 111-5).   This Small Business Innovation Research (SBIR) Phase II project seeks to reduce the cost and risk of manufacturing nanoparticle/resin blends for
Low Cost-Reduced Risk Manufacturing Process for Nanocoatings
It is widely believed that decisions arrived at by groups of decision makers are superior to those made by individuals, hence the  common aphorism that 'two heads are better than one.' In prior research the Principal Investigators found that th
(ARRA) Collaborative Research: Experimental studies on group decision making in strategic environments
Development scholars and policy planners regard cooperative producer organizations as a core component of poverty reduction strategies, but little is known about the social dynamics that make some of these organizations more successful than oth
Social and Spatial Networks, Social Capital, and Leadership Accountability in Rural Development: A Study of Uganda's Agriculture Productivity Enhancement Project
The objective of this research is to develop a fabrication technique for producing complicated gradient-index electromagnetic components in the millimeter-wave and terahertz spectral bands. The approach is to modify existing rapid-prototyping h
Gradient-index mm-Wave/Terahertz Components via Polymer-jetting Rapid Prototyping
The objective of this research is to develop a novel nanomechanical sensor with single molecule detection sensitivity. The approach is to form a hybrid cantilever with a functional virus at its tip. The cantilever/virus hybrid structure will be
Hybrid Bionanomechanical Systems for Single Molecule Detection
The objective of this program is to devise and demonstrate architectures incorporating mode-evolution based, integrated polarization splitter and rotator devices in silicon photonics, in order to enable polarization sensing and manipulation fun
Innovative Silicon Photonics for Polarization Sensing and Control
INVESTIGATION OF NANOSCALE SPIN DYNAMICS AND INTERACTIONS WITH SCANNING PROBES This proposal will investigate the spin torque induced switching and ferromagnetic resonance dynamics of small patterned magnetic tunnel junction devices using scann
Investigation of Nanoscale Spin Dynamics with Scanning Probes
The objective of this research is to fill the technological 'gap' at the THz spectral region, by developing the first generation of THz graphene-based photodetectors with exceptional sensitivity, dynamic range, response rate and non-cryogenic o
Collaborative Research: Graphene-Based THz Photodetectors
Title: Collaborative Research: RoboBees: A Convergence of Body, Brain and Colony. With impacts ranging from industrial automation to household chores, robots are poised to become an integral part of modern life. Technological progress over the
Collaborative Research: RoboBees: A Convergence of Body, Brain and Colony
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).In this project, researchers at the University of Washington will address two of the overriding goals of the GEOTRACES program: advancing our under
US GEOTRACES N. Atlantic: Measuring the 13C-DIC distribution and quantifying the impact of organic matter export on 13C, nutrients and biologically active trace metals
This project will study the processes that remove nitrogen oxides in high latitudes during winter by measuring near-surface nocturnal nitrogen oxide levels, quantifying their lifetimes through a steady-state analysis, and correlating their loss
Role of Ice in High Latitude Nitrogen Atmospheric Chemistry
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  The most dramatic geologic events - such as earthquakes and volcanic eruptions - occur along the margins of the mosaic of plates that cover the s
ARRA Closing the global plate circuit: High resolution reconstructions of African plate motion from 0 to 20 Ma
Current Late Jurassic-Early Cretaceous time scale based on the M-sequence marine magnetic anomalies are not well constrained due to the lack of accurate radiometric ages and due to their reliance on the assumption of constant oceanic spreading
A M-sequence geomagnetic polarity time scale that minimizes global spreading rate variations and incorporates cyclostratigraphic information
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).    Microbial mats are conspicuous components of many benthic marine and aquatic settings. A subset of these microbial mats binds sediments to form
Collaborative Research: Were protists the beginning of the end for stromatolites?
In this project, investigators propose to develop a programming environment for easing the development of portable high-performance applications for GPUs and accelerators by automatic generation of OpenCL code from annotated C programs provided
(ARRA) Collaborative research: An environment for high-productivity high-performance computing using GPUs/accelerators
Collaborative Research: Topology-Aware MPI Communication and Scheduling for PetascaleSystems
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  The pH of the ocean is predicted to decrease by 0.2-0.5 pH units in the next 50 to100 years as a result of increasing atmospheric CO2. To date al
Will Ocean Acidification Diminish Particle Aggregation and Mineral Scavenging, Thus Weakening the Biological Pump?
The objective of this award is to develop a fundamentally new approach to construct families of geometric skeletons for 2- and 3-dimensional geometric shapes that can be either rigid or undergoing drastic topological deformations. Our approach
Geometric Skeletons for Topologically Evolving Domains
BOARD OF TRUSTEES OF COMMUNITY COLLEGE DISTRICT #508 (INC)
IRES US -Kenya:  Effects of Habitat changes on distribution, abundance, and resource exploitation by globally threatened and forest specialist birds in Arabbuko-Sokoke Forest, Kenya    - Developing Global Scientists and Engineers.
IRES  US - Kenya: Effects of Habitat changes on distribution, abundance, and resource exploitation by globally-threatened and forest specialist birds in Arabuko-Sokoke Forest, Kenya
The objective of this research is to (1) use a machine to enhance a manual welding process that is currently operated and controlled by a human welder and (2) establish the foundation for the resultant machine-human cooperative control of the w
Machine-Human Cooperative Control of Welding Process
The mechanical properties of polymers in confined domains are examined from a novel combination of nanoscale indentation experiments and theory. The work will be directly applied to thin polymer films and then extended to model polymer nanocomp
New Approach to Nanoindentation Experiments and Modeling: Toward Fundamental Understanding of Thin Polymer Films and Polymer Nano Composites
The objective of the proposed work is to provide fundamental understanding of the nonlinear dynamics of electrostatically actuated doubly-clamped carbon nanotubes,including the effect of slack, and explore in depth the consequences, advantages,
COLLABORATIVE RESEARCH: EXPLORATION OF THE NONLINEAR DYANMICS OF NEMS CARBON NANOTUBE RESONATORS
Metal-organic frameworks (MOFs) are potential candidates for H2 storage because they can reversibly absorb hydrogen at low temperatures. The critical issue is their low hydrogen capacity at room temperature or above, because the interaction bet
Catalytic Activation, Spillover, and Storage of Hydrogen on Transition-metal/MOFs
This project addresses a significant area of uncertainty in our understanding of biogenic sources of gases and aerosols to the atmosphere by updating a 3-dimensional global model (Community Atmospheric Model - Chemistry coupled with Community L
Impacts of the Biosphere on Global Tropospheric Chemistry and Climate
The Department of Geosciences at the University of Arizona will receive funds to build a new electron imaging facility to support the geochronological research of the Arizona LaserChron Center (ALC), and also to serve a broad range of research
Acquisition of a New Electron Imaging Facility in the Department of Geosciences at the University of Arizona
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). Granted funds will support acquisition of an electron backscattered diffraction (EBSD) camera and an energy dispersive spectrometer (EDS) for a re
Acquisition Of Integrated EBSD/EDS Attachments and Software for The Field Emission SEM At The University of Southern California
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5) and supports the design and construction of a new instrument capable of measuring with high sensitivity the torsional oscillations of the Earth's s
DEVELOPMENT OF NEW ROTATIONAL SEISMOMETERS OF HIGH SENSITIVITY
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). This grant partially funds a full-time laboratory technician for the Georgia Institute of Technology cosmogenic nuclide geochronology laboratory.
ARRA:  EARLY CAREER: TECHNICIAN SUPPORT - GEORGIA INSTITUTE OF TECHNOLOGY COSMOGENIC NUCLIDE GEOCHRONOLOGY LABORATORY
or directional nerve growth factors in these systems, a surprising outcome to scientists in a field that had long thought only classical (already identified) neurotrophins could play such a role. The use of microfluidic technologies as well as
Role of the cytokine macrophage migration inhibitory factor (MIF) as a neurotrophin in Zebrafish neurogenesis
and actively engaging with evidenced based medical care for suicide ideation and associated problems of depression, PTSD, substance abuse, these Native soldiers/veterans in rural communities are doubly at risk for suicide as they are isolated
Coming Home: The Reintegration of Native Yup'ik Soldiers/Veterans into their rural communities
Multifunctional Nanoparticle Assemblies for Optical Diagnosis and Treatment of Disease
Ultra high-throughput holographic on-chip cytometry using inertial micro-fluidics  Flow cytometry is a workhorse of modern cell biology and clinical diagnostics, but suffers from three significant downsides: (i) limited throughput; (ii) high co
IDR: ULTRA HIGH-THROUGHPUT HOLOGRAPHIC ON-CHIP CYTOMETRY USING INERTIAL MICRO-FLUIDICS
This award sponsors research and development towards the laboratory synthesis of  novel biomaterials with controllable properties and characteristics at the nano dimension. The expected outcome of the sponsored work is a novel test material wit
Bio-templated nanomaterials for environmental remediation applications
To support the preservation of jobs that are threatened by declines in philantrhopic and otehr support during the current economic downturn
Ruminants, like cows and sheep, use specialized stomachs containing fermenting bacteria to digest plant material. Some non-ruminant animals, such as kangaroos and langur monkeys, also have specialized stomachs containing fermenting bacteria. Ba
Characterization of Essential Fatty Acid Conservation Mechanisms in Ruminants
Collaborative Research: Development of a Technology for Real Time, Ex Ante Forecasting of Intra and International Conflict and Cooperation
Eyewitnesses are a crucial source of information for crime scene investigators. Accurate information facilitates crime solutions; inaccurate information leads to wasted investigator effort or, even worse, wrongful convictions. How investigators
RUI: The Dynamic Interaction Between Investigator and Eyewitness: Effects on Memory Reports and Interviewer Behavior
Self-control is an important key to success in life insofar as individuals who succeed at self-control enjoy more satisfying interpersonal relationships, better physical health, and greater subjective well-being than do people who fail at self-
DISTINGUISHING IMPULSE STRENGTH FROM SELF-CONTROL STRENGTH AS CAUSES OF SELF-CONTROL FAILURE
ntellectual merit Tetrapyrroles are essential biomolecules required for metabolism in all organisms. They form the basis of heme moieties, which act in energy-generating electron transfer reactions, and they also form the core of chlorophylls,
: Regulation of 5-Aminolevulinic Acid Biosynthesis in the Bacterium Rhodobacter sphaeroides
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  Statistical models in social and natural sciences typically include a parameter of interest as well as other parameters that need to be estimated
Collaborative Research: Small Bandwidth Asymptotic Theory for Kernel-Based Semiparametric Estimators
Are new international laws promoting the rights of children effective? Under what conditions? Since 1989, nearly every country in the world has ratified the Convention on the Rights of the Child, making it the most widely ratified treaty ever.
The Cost of Rights or the Right Cost? The Impact of Global Economic and Human Rights Policies on Child Well-Being
This project will test two hypotheses to explain striking landforms found in thick loess of the  Great Plains and other regions, including large, apparently wind-aligned linear scarps and troughs. The broader significance of these landforms lie
Collaborative Research:  Linking loess landforms and eolian processes
Understanding the causes of major extinction events is often hampered by a lack of rigorous environmental and biological data and limited geographic coverage, which can help determine how closely events in one region are mirrored in others. The
Geographic Variation in Environments and Extinction in the Caribbean
We propose a study of magnesium isotope variations produced by weathering processes and biogeochemical cycling in the surface environment of Hawaii. Recent work has demonstrated Mg isotopic variations among fresh rocks, soils, stream, spring an
INVESTIGATION OF MAGNESIUM ISOTOPE FRACTIONATION DURING BASALT WEATHERING
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). The most striking large-scale pattern in biological diversity is the dramatic increase in the number of species and higher taxa from the poles to
COLLABORATIVE RESEARCH:  THE DYNAMICS OF GEOGRAPHIC RANGES:  ORIGIN AND MAINTENANCE OF MARINE DIVERSITY GRADIENTS
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  In this project funded by the Major Research Instrumentation (MRI) Program, the PI's will develop a new, international (8-nation), broadband seis
MRI-Consortium: Development of a Greenland Ice Sheet Monitoring Network
The study of plant biology has advanced our understanding in areas not only related to agriculture and food quality, but also in the areas of human biology. Recent advances in technologies in the area of biochemistry, cell biology and genetics
MRI: Acquisition of Laser Capture Microdissection Instrumentation for Michigan State University
With this award from the Major Research Instrumentation (MRI) program, Facundo Fernandez and colleagues Thomas Orlando, Mark Sullards and Dongmei Wang from Georgia Institute of Technology will develop an atmospheric pressure ion mobility mass s
ARRA: MRI: DEVELOPMENT OF ATMOSPHERIC PRESSURE ION MOBILITY QUADRUPOLE TIME-OF-FLIGHT MASS SPECTROMETER FOR AMBIENT IMAGING
This proposal is for the acquisition of state-of-the-art thermal analysis and calorimetry instrumentation, namely a thermobalance and a heat flow calorimeter. The thermobalance is combined with evolved gas analysis (EGA) by coupled mass and Fou
MRI: Acquisition of Thermal Analysis and Calorimetry Equipment for Multiple Applications Emphasizing Research on Sustainable Fuels
This instrument development project creates a new type of 3D fluorescence and phosphorescence lifetime imaging microscope based on a novel decay time measurement technique that operates in real-time.  The decay time or lifetime is the time a mo
MRI: DEVELOPMENT OF A REAL-TIME FLUORESCENCE AND PHOSPHORESCENCE LIFETIME IMAGING 3D MICROSCOPE BASED ON A NOVEL ANALOG ACQUISITION METHOD
Temperature-dependent sex determination (TSD) was first reported 40 years ago in an African lizard. It has since been shown that temperature determines sex in some fish and amphibians, several lizards, numerous turtles, and all crocodilians. Ne
Genomic and Genetic Analysis of Temperature-Dependent Gender Determination
The Cyber-ShARE Center of Excellence proposes to establish a collaborative visualization theater, the Cyber-ShARE Collaborative Visualization Theater (CCVT), to present high-resolution displays of scientific datasets for exploratory, monitoring
MRI: Acquisition of the Cyber-ShARE Collaborative Visualization System
The PIs plan to acquire a research-grade gamma spectroscopy instrument for making ultra-low radiation measurements of the type needed over a wide range of emission energies (fractions of an MeV to several MeV). Presently, there are only a handf
MRI:  Acquisition of an Ultra-low Background Gamma Spectroscopy Platform for Measuring Ionizing Radiation
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  MRI: Acquisition of Vis-NIR Tunable Femtosecond Mode-Locked Laser System for Nanophotonic Devices and Materials Research Boise State University (
MRI: Acquisition of Vis-NIR Tunable Femtosecond Mode-Locked Laser System for Nanophotonic Devices and Materials Research
Nuclear Magnetic Resonance (NMR) spectroscopy is one of the most powerful tools available to chemists for the elucidation of the structure of molecules. It is used to identify unknown substances, to characterize specific arrangements of atoms w
MRI: Acquisition of High-sensitivity NMR Capabilities for the University of Oregon Magnetic Resonance Facility
This Small Business Innovation Research (SBIR)Phase II project seeks to overcome the principal impediments of the inconsistent quality of metal matrix composite (MMC) materials from fly ash and aluminum. This project utilizes highly processed a
SBIR Phase II: Improved Manufacturing Methodology for Aluminum Ash Metal Matrix Composite Materials
The goal of the project is to develop a smart sensor network integrated with Zero-Power Radio Frequency Identification-Sensing Tags (FRID-ST) that combines the technology of a digital MEMS sensor and a reconfigurable RF antenna for blood bag ap
Zero-Power Radio Frequency ID Sensing Tags
This Small Business Innovation Research (SBIR) Phase II project addresses the need for crops with increased yield. Yield is directly related to nitrogen (N) utilization and is dramatically affected by climate. Plant Sensory Systems has develop
SBIR Phase II: GABA-Mediated Nitrogen Efficiency
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  This Small Business Technology Transfer (STTR) Phase II project is creating create novel technologies for the realization of a cost-effective, op
STTR Phase II: Optical Fiber Distributed 60 GHz Wireless Personal Area Network
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  This Small Business Technology Transfer (STTR) Phase II project proposes to create an in-home gait training device that allows a post-stroke pati
STTR Phase II: In-Home Rehabilitation System for Post Stroke Patients
The objective of this research is to develop the fundamental scientific and engineering principles that will form and drive the development of k-space multifunctional acoustic wave devices as potential components in telecommunication technology
K-Space Multifunctional Acoustic Wave Devices
'Professor Michael R. Hoffmann of California Institute of Technology is supported by the Analytical and Surface Chemistry Program in the Division of Chemistry to conduct research in an international collaboration with Professor John T. Irvine
International Collaboration in Chemistry: Enhancing Direct Photoelectrochemical Conversion of Carbon Dioxide
Intellectual Merit: Under this award the Principal Investigator (PI) will continue investigating how microphysics and kinematics affect storm electrification and lightning production by using lightning mapping, electric field, radar, and other
Microphysical and Kinematic Storm Properties Affecting Electrification and Lightning Production
Z4 ENERGY SYSTEMS, A LIMITED LIABILITY COMPANY
An Advanced Aeroelastic Thermoplastic Composite Blade for Residential-Scale Wind Turbines  This Small Business Innovation Research Phase II project will capitalize upon Phase I and Phase IB success by prototyping/validating a novel, self-regula
An Advanced Aeroelastic Thermoplastic Composite Blade for Residential-Scale Wind Turbines
This Science, Technology, and Society project supports scholarship that will result in a book about ethics and ecology, in particular, the concept of harm to nature. The conceptual and normative analysis will focus on the recent history of atte
Harms to Nature: A Normative and Conceptual Analysis
The ultimate objective of this project is to determine the acceleration mechanism responsible for strong increases of radiation belt electron fluxes during geomagnetic storms. The project will calculate Ultra Low Frequency (ULF) wave power from
GEM Postdoc: Characteristics of Ultra Low Frequency (ULF) Waves Associated with Electron Acceleration to Relativistic Energies
SHINE Postdoc: Interplanetary Scintillation (IPS) and Solar Mass Ejection Imager (SMEI) 3D-Reconstructions and Imaging of the Solar, Heliospheric, and INterplanetary Environment  Remote-sensing observations of the inner heliosphere currently us
Shine Postdoc: Interplanetary Scintillation (IPS) and Solar Mass Ejection Imager (SMEI) 3D-Reconstructions and Imaging of the Solar, Heliosperic, and Interplanetary Environment
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  Like humans, ground-dwelling birds (ostriches, emus, chickens, guineafowl, etc.) move by alternate motion of their two legs. Avian bipedal locomo
Kinematics and kinetics of long-axis rotation in avian bipedal locomotion  Federal Award ID Number: 0925077
Development of a Low Cost Form of Maglev Transportation Using Electrodynamic Wheels  The objective of this research is to experimentally and numerically verify that a low cost, high efficiency, maglev vehicle can be built.  The approach is to e
Development of a Low Cost Form of Maglev Transportation Using Electrodynamic Whe
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  Block-molded expanded polystyrene (EPS) geofoam is a type of cellular geosynthetic with a long history of successful applications in geotechnical
CYCLIC STRESS-STRAIN CHARACTERISTICS OF EPS GEOFOAM
A Collaborative Proposal Involving CMU, CUNY, NYU, Stony Brook, UMD, Cornell, JPL   This Expedition, under the directorship of Lead PI Edmund M. Clarke, will develop new computational tools to help scientists and engineers analyze and underst
The research objective of this BRIGE award is to initiate the first phase of a research program to develop a civil infrastructure asset management system to predict and optimize public school management of facility components that impact enviro
BRIGE: Sustainable Healthy Schools: A Framework for Managing the Environmental Health of Public School Infrastructure
The research objective of the proposed research is to employ electrodeposition techniques in the design of a manufacturing route for creation of fully dense metal-nonmetallic selective laser sintered parts. The approach will be to adapt and mod
Electrochemical Infiltration of Selective Laser Sintered Preforms
This award is for a suite of comprehensive field observations to elucidate and quantify the mixing processes in the inner shelf and to directly examine the impact of these processes on inner shelf biological distributions. Predictive modeling o
Collaborative Research: Lateral Mixing and Dispersion on the Inner Shelf
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  With this award the PI will test four hypotheses about what drives changes in the Atlantic overturning circulation on orbital timescales over the
Climate forcing of Atlantic overturning over the last 3 Myr
This grant provides funding for the development of mathematical models integrating production, inventory and pricing decisions in a host of centralized/decentralized supply chain systems as well as the development of efficient algorithms to sol
Coordinated Pricing and Inventory Management
As novel applications for nanocrystalline materials continue to emerge, there is an increasing need for new approaches to manufacture these materials efficiently, at high yield, and with minimal damage to the environment. In this project, two g
Engineered Microfluidic Mixing for Green Nanocrystal Manufacturing
Collaborative Research: The dynamics of sediment-laden river plume and initial deposition off small mountainous rivers     The goal of the project is to improve our current capability in coastal ecosystem management and hazard prevention/mitiga
The dynamics of sediment-laden river plume and initial deposition off small mountainous rivers
The objective of this proposal is to design a multifunctional chemiresistor sensor array which integrates a variety of preselected functionalized gold nanoparticles and supersensitive electrometers. The availability of such a device will be ben
BRIGE: The Design and Characterization of a Multifunctional Chemiresistor Sensor Array
Highly Organized Two & Three Dimensional Single Wallrd Carbon Nano-tubes - polymer Hybrid Structures for Diverse Flexible Devices & Systems.
Highly Organized Two & Three Dimensional Single Wallrd Carbon Nanotubes - Polymer Hybrid Structures for Diverse Flexible Devices & Systems
The purpose of this project is to explore the potential of using natural bio-surfactants as a delivery system for anti-microbial agents or other therapeutic agents. This type of delivery system could be useful in human health applications and a
BRIGE: Proposal to Study Self-Assembling Siderophore Vesicles
Dept of Chemical and Biological Engineering
This project seeks to study the nonlinear, multi-modal, and stochastic dynamics of microcantilevers tapping on samples in liquids to significantly improve next generation dynamic Atomic Force Microscopy (dAFM) for biology and medicine. The prop
GOALO:Nonlinear, Multi-modal and Stochastic Dynamics of Low Stiffness Microcantilevers in Liquid Environment Atomic Force Microscopy
Iron limitation of heterotrophic bacteria has substantial biogeochemical implications, including lower assimilation efficiencies and reduced incorporation of CO2 into biomass. Marine bacterioplankton also have a large impact on iron speciation
ARRA: COLLABORATIVE RESEARCH: IRON LIMITATION, CARBON METABOLISM AND SIDEROPHORE PRODUCTION IN MARINE BACTERIA - A SYSTEMS BIOLOGY APPROACH
The objectives of this research are to i) gain an understanding of and ii) create a predictive methodology for crack initiation and overall crystal quality evolution for Aluminum Nitride (AlN) single crystals during processing.
GOALI/Collaborative Research: Understanding Cracking and Defect Formation During AIN Crystal Growth
The study will promote understanding of sediment dispersal in estuaries through an investigation of the Delaware River estuary. Coordinated studies of water-column sediment flux, deposition, and resuspension are planned and the PIs hope to esta
Collaborative Research: Sediment Sources, Transport Mechanisms, and Fluxes in a Coastal Plain Estuary
PRISM:  Attracting students to mathematics, physics, and biology through inter-disciplinary research and discovery
Liquefaction is an important cause of damage to civil infrastructures during earthquakes, and techniques that can minimize the liquefaction susceptibility of a site, with no ground disturbance can greatly impact geotechnical earthquake engineer
Engineering the Pore Fluid of Sands with Highly Plastic Nano-Particles for Liquefaction revention
Arts and the American Recovery & reinvestment Act of 2009
Lithium-ion secondary batteries are considered an attractive power source for portable devices, hybrid electric vehicles (HEVs), and large electric facilities. Lithium manganese spinel LiMn2O4 and olivine-type lithium iron phosphate (LiFePO4, L
FLAME ASSISTED SYNTHESIS OF LI ION BATTERY MATERIALS
from nanoparticles and attaching acidic side chains to the hairs. Mixing these functionalized nanoparticles in solvent with a structurally robust, crystallizable polymer and drawing off the solvent in a controlled manner induces a phase separa
Composite Polymer Membranes for Energy Conversion
Explanations for why CO2 varies on glacial timescales and why the ice core records are out of sync on millennial-centennial timescales most likely reside in the deep ocean. To learn how we must first know how this reservoir changes under diffe
Deep-sea coral records of past ventilation rate and temperature in the Southern Ocean and North Atlantic
This project will investigate the paleo-geological history of Ocean Anoxic Event II (OAEII, ~94 Ma) by iron isotopic analyses (d56Fe) of total iron in archived sediment cores from the proto North Atlantic and bordering Western Interior Seaway,
What are the Sources and Mechanisms of Iron Enrichments during Oceanic Anoxic Event 2?  Evidence from Iron Stable Isotopes
NSF support for equipment upgrades and components form an integral part of continuing the vital role of the Arizona AMS Laboratory and maintaining our equipment at modern standards. The facility's two machines are in need of vacuum equipment an
Upgrades to the NSF Arizona Accelerator Mass Spectrometry Laboratory
'GEOTRACES is a newly initiated international oceanographic program to identify processes and quantify fluxes that control the distributions of key trace elements and isotopes in the oceans and to establish an understanding of the sensitivity
US GEOTRACES North Atlantic Section: Sample collection for iron stable isotopes
The overall goal of the GEOTRACES program is to improve our understanding of the sources, distributions, and sinks of geochemically significant trace elements and their isotopes (TEIs) in the world’s oceans. After several years of coordinatio
GEOTRACES Atlantic Section: Aerosol and Rainfall Collection and Analysis
This award will provide funding to replace equipment for sedimentary geology and biogeochemistry. The main items which will be improved or replaced are a rock saw, shatterbox, centrifuge, ovens, a balance, coulometer and spectrophotometer. All
Upgrade of Sedimentary Geology Preparation and Marine Sedimentary Biogeochemistry Laboratories
STTR Phase I: Holistic Separation of High Purity Metallic and Semiconducting Single-Wall Carbon Nanotubes
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  This Small Business Technology Transfer Phase I project is responsive to topic Multi-Functional Materials (MM), Subtopic Materials for Sustainabi
STTR Phase I:  Advanced Poly(lactide) (PLA) Materials for Extruded Sheet Applications
FISCHOFF NATIONAL CHAMBER MUSIC ASSOCIATION, THE
SAINT PAUL CHAMBER ORCHESTRA SOCIETY, THE
The objective of this research project is to achieve fundamental advances in software technology that will enable building cyber-physical systems to allow citizens to see the environmental and health impacts of their daily activities through a
CPS:Medium: CitiSense - Adaptive Services for Community-Driven Behavioral and Environmental Monitoring to Induce Change
Large-eddy simulation (LES) is one of the most promising numerical techniques for modeling complex turbulent flows in a variety of applications ranging from engineering to geophysical flows. Today, one of the main obstacles to the widespread us
Collaborative Research: Explicit Filtering and Adaptive Mesh Refinement for Large-Eddy Simulations
IN THE HEART OF THE BEAST PUPPET AND MASK THEATRE
To support the preservation of jobs that are threatened by declines in philanthropic and other support during he current economic downturn, as described in application AO9-904911 and approved budget.
Native American Housing Block Grant, Competitive - NAHASDA-eligible activities include new construction, site improvement, utility services, administration and planning.
Native American Housing Block Grants (Competitive) Recovery Act Funded
NAHBG Competitive New Construction of  18 Rental Units
LAC COURTE OREILLES TRIBAL GOVERNING BOARD
John Fiske, the Seasonal Widldrness Monitor for Central Nevada accomplished the following during his term of employment:   Campsites documented: 55 People encountered and documented in the Wilderness areas he's focused on: 15  Invasive Weed Pop
Central Nevada Wilderness Seasonal Monitor
native American housing Block Grant Competitive funds for new housing construction
Native American Housing Block Grant, Competitive - New construction and rehabilitation of affordable housing
Constrution of Six New Housing Units and Rehabilitation of 25 Units of Affordable Housing
Construction of six new single family houses for low income Indian families
Native American Housing Block Grants (Competitive)
Development of 10 new Homes on the Manzanita Indian Reservation.
Native American Housing Block Grant, competitive-NAHASDA-eligible of affordable housing.
Stimulating Growth and Stability for Native Families
Objection is to reduce hazardous fuels (defensible space and fuel breaks) on private land and around communities in alignment with the National Fire Plan policies that protect homes in the wildland urban interface (WUI) and provide new or conti
2009 County CWPP Hazardous Fuels Treatment
Implement wildfire mitigation and forest restoration treatments in high-priority areas of Colorado.
This project is enhancing and protecting the Carson River system, reducing hazardous fuels and providing work opportunities for currently unemployed individuals by: Employing two teams of at least 10 individuals each to conduct the following ac
Carson River Streambank and Stabilization
The proposed project is focused on fuels reduction and improving ecosystem functions of riparian lands in Clark County. This includes removing non-native woody biomass and replanting cleared areas with native vegetation.  We will focus our effo
Perennial Pepperweed and Tamarisk Removal, Pepperweed Control and Fuels Reduction
The grant funding provided will result in multiple upgrades that will improve ongoing operations of the BioMass Plant located at Northern Nevada Correctional Center.
Northern Nevada Correctional Center Bio-Energy ARRA Project # WFM-0460-01B
The purpose of this award is to reduce the risk of catastrophic loss due to wildfire within and around communities at risk located in the California portion of the Lake Tahoe Basin.  The following outcomes are expected upon completion of this p
Hazardous fuels reduction on non-federal properties within the California portion of the Lake Tahoe Basin.
Reduce the risk of catastrophic wildfire in high risk communities through a coordinated effort of fuels reduction projects across private and state lands within the wildland urban interface.
Greenwater Community Wildfire Protection Plan Firesafe/Shaded Fuel Break.
Mississippi's Hazardous Fuels Reduction Program - This project is to reduce hazardous fuels around communities, homes and public infrastructure around the state.  The goal is to establish 300 miles of fuel breaks, treat approximately 6000 acres
Mississippi's Hazardous Fuels Reduction Program
Hemlock Woolly Adelgid (HWA), an exotic destructive pest of Eastern and Carolina Hemlock trees, was first detected in South Carolina in 2001.  Since that time, HWA have been detected in all South Carolina counties with hemlock trees (Oconee, Pi
Hemlock Woolly Adelgid Control to Protect Watersheds in South Carolina
Purchase and install doweling machine(s)that will utilize small diameter trees not suitiable for manufacture of lumber and tops from trees that would be normally be burned or left in the woods and
Rice CSAH 48 SB Entrance Ramp to 0.1Mi N TH 21 NB and SB lanes-Thick Bituminous Overlay
North Jct TH 59 to Grant County Line (EB & WB)-concrete rehabilitation. Rest Area Parking/Site Preservation (Iverson, Hansel)
Replace Utilities, Reconstruct Pavement and Signal Improvement in City of St. Peter;Concrete From Jefferson to Chatham;Bit from Chatham to Union St and S Jct TH 22 to Jefferson St; includes Streetscape/ped Accommodation (Design-Build)
Guardrail Replacement at Various Locations in District 8
Rest Area and Interchange Sign Replacement
Replace BR 7139 1954 Steel Beam Concrete Deck Structure with three 12' x 8' Box Culverts
Replace BR 7137 with a Continuous Concrete Slab Span (New BR 12551)
Replace BR 56507 over Otter Tail River on Concord St
1.37 Mi S of Kandiyohi CR 77 to TH 7, Grading, Aggregate Base and Surfacing
Replace BR 6839, 4th St Over Bear Creek, with BR 55588, Precast Concrete Beam Structure and Approach Grading
From Exit Ramp to MN 95 to S of CSAH 9 in North Branch and Harris
Pavemetn Preservation N Junction of 35E/35W to N of TH 8 Bituminous Mill and Overlay, includes CMPS Aux Lanes
N of CSAH 42 to N Jct TH 55 in Rosemount and Inver Grove Hts. Bituminous Mill and Overlay & Deck Repair on Bridges
At TH 41 , Carver CSAH 10 (Engler Blvd) and Carver CSAH 11 Interchanges in Chaska-Landscaping
East side of Metro District Guardrail Improvement / Replacement
The Forest Service is requesting an eight person SCC crew whose members possess skills needed for working, backpacking, and camping in remote locations for extended periods of time with minimal US Forest Service contact or supervision.  The SCC
Lincoln National Forest Trail Maintenance
THE STUDENT CONSERVATION ASSOCIATION INC
The award provided funding for a Student Conservation Association (SCA) program at Payette National Forest, with services to the Forest including heavy trail maintenance on approximately  25 miles of trail, improving public access and restoring
This award provided funding for an Student Conservation Association (SCA) program to provide maintenance, repair and reconstruction of trails including the Pacific Crest Trail, in wilderness areas to include Hoover Wilderness, Mt Rose Wildernes
FRIENDS OF THE MINNESOTA CONSERVATION CORPS INC
The Minnesota Conservation Corps, an environmental nonprofit that engages young people in outdoor natural resource work, received $557,000 in Recovery Act funds from the Superior National Forest for trail maintenance work in Northeast Minnesota
Superior National Forest Trail Maintenance
To provide safe public passage while also providing upstream passage to fish and other aquatic organisms and reduce the amount of sedement delivered downstream.
Pere Marquette Watershed Road Stream Crossings Improvement Project
Agreement between Conservation Resource Alliance and the USDA Forest Service, Huron-Manistee National Forests for implementation of a portion the Pere Marquette Watershed Road Stream Crossings Improvements Project including Pine Silver Creek Cu
Pere Marquette Watershed Road Stream Crossings Improvements Project
Create and save jobs for the refuse control services, build stregthen and sustain the foundation for long term economic growth of this service for the tribe. Streghten the ability for self sufficiency for this program, provide supportive servic
CENTRAL COUNCIL TLINGIT AND HAIDA INDIAN
Central Council of Tlingit & Haida Indian Tribes of Alaska will use the American Recovery Act funds to help low-income people  be ome more self-sufficient and create jobs through education and training.
Tribal Community Services Block Grant, American Recovery & Reinvestment Act of 2009 Plan
our goal is to provide services to apache families who are attempting to transition off state programs carried out under part A of title IV of the social security act and assist tribal members with pre-employmnet seminars that will demonstrate
The program is established to identify eligible CSBG ARRA recipients, and provide the opportunity for them to obtain or enhance the necessary skills to secure meaningful employment.  Targeted individuals will include those who have recently suf
EXECUTIVE OFFICE OF THE STATE OF COLORADO
The purpose of the award is to assist the grantee in carrying out a national service program as authorized by the National and Community Service Act of 1990, as ammended (42 U.S.C. Sect 12501 et seq.) and in the American Recovery and Reinvestme
Colorado Governor's Commission on Community Service
The award focuses on tutoring for youth in grades K-12 and increasing the number of individuals that engage in services provided by local non-profit organizations.
FINANCE AND ADMINISTRATION, TENNESSEE DEPARTMENT OF
Award focuses on home weatherization, tutoring and mentoring,  child abuse and neglect prevention, and senior health/independence.
EXECUTIVE OFFICE OF THE STATE OF CALIFORNIA
This grant award supports 144 AmeriCorps service positions dedicated to activities that address community challenges created as a result of the economic crisis.  AmeriCorps members focus on developing volunteer infrastructure to build capacity
To carryout out a national service program as authorized by the National and Community Service Act of 1990 and in the American Recovery and Reinvestment Act.  AmeriCorp members focus on mentoring and tutoring At-Risk Youths.
The purpose of this award is to assist the grantee in carrying out a national service program as authorizeed by the National and Community Services Act of 1990, as amended (42 U.S.C. 12501 et seq.) and in the American Recovery and reinvestment
Kentucky Commission - Recovery Formula Prime
The AmeriCorps members funded through the Recovery Act will engage in various activities in service activities to communities affected by the economic crisis. AmeriCorps Members will empower children, youth, and families in southwest Baltimore
Recovery Act funding through the AmeriCorps program will be awarded as grants to current Wyoming AmeriCorps sub-grantees with a proven track record and demonstrate the capacity to efficiently and effectively draw upon this new resource to assis
The purpose of the Interval House AmeriCorps Recovery program is to meet the increased demand for housing, financial, employment, and healthcare services for victims of domestic violence impacted by the declining economy.
AmeriCorps members assist low-income homeowners by providing weatherization and energy efficiency repairs.
AmeriCorps Legal Fellows (AmeriCorps members who are barred attorneys) provide legal assistance to people affected by the foreclosure crisis and others in dire economic need.
Equal Justice Works AmeriCorps Recovery Fellowships
AmeriCorps members recruit, train and support Power Lunch volunteers from the community to read one-on-one to low-income children
The purpose of the ARRA award for Notre Dame Mission Volunteer-AmeriCorps Program is to alleviate the effects of the current economic crisis while giving youth and families the tools to meet educational needs.  The primary purpose for Notre Dam
Recovery Notre Dame Mission Volunteer Program, Inc.
Recovery grant awarded by Corporation for National and Community Service in the amount of $104,800 to engage 8 full time AmeriCorps members (ages 18-25)in one year of community service implementing energy efficiency services in Minnesota metro
Recovery Access to Care Through Services (ACTS) The Philadelphia AIDS Consortium TPAC provides Education, Outreach, Prevention Counseling and testing, Food  and other medical and supportive services for people infected and affected by HIV/AIDS.
Recovery Access to Care Through Services (ACTS)
Full-time AmeriCorps Members will create, improve, and expand the services of local community and faith-based organizations, providing valuable services to community members in the areas of housing, education, youth development, public health,
crushed aggregate on 7.5 miles of forest roads
Recovery Act Road Project Agreement between Town of Chittenden, VT and the USDA Forest Service, Green Mountain & Finger Lakes National Forest work on Forest Rd. #99
FH6 (Town Highway No. 3) Kelley Stand Road. Road preparation and dust control place 6in gravel, grade, and compact on full width of road (approx. 2,816 CY)
Recovery Act Road Project Agreement 09-RO-11094419-065
Provide program management and supervision for VolunteerMaine Recovery Act VISTA Project. PROJECT OVERVIEW Since 2007, the Maine Commission for Community Service has sponsored the VolunteerMaine VISTA Project. The goal of the project is to deve
The Wisconsin Department of Public Instruction Recovery VISTA Project goal is to build capacity of community involvement and access to local resources in economically depressed communities by implementing a sustainable process for community par
Wisconsin Department of Public Instruction VISTA Project; Economic Recovery with WI Public Libraries
VISTA Project meets Recovery Areas of employment assistance; access to benefitsfor the unemployed; and access to health care for the unemployed undesr the Strategic Initiatives of Mobilizing more Volunteers; and ensuring a Brighter Future for A
This award provides for ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start Program in Kalihi, Oahu, Hawaii and Early Head Start Pro
ARRA Supplemental Grant allows our program to implement a cost-of-living increase of 1.84%. and improve staff qualifications and assist with the implementation of career development programs for staff that support ongoing improvement of their s
INYO MONO ADVOCATES FOR COMMUNITY ACTION INC
ARRA cost of living adjustment and Quality Improvement funding consistent with the provisions of the Head Start Act.  Head Start promotes the school readiness of low-income children through the provision of comprehensive health, development and
COMMUNITY ACTION COMMISSION OF SANTA BARBARA COUNTY
Early Care & Education for Children Ages 0-5 and pregrant women services, include health screening nutritional meals, parent education and activities, mental health services.   We serve 1098 head start and early head start children in 27 differ
This award is for the Head Start and Early Head Start program which provides services to over 3248 Head Start children ages 3-5 and over 186 Early Head Start children and pregnant women in Riverside County, California.  Services are offered for
YOUNG MEN'S CHRISTIAN ASSOCIATION OF BERKELEY
ARRA COST OF LIVING ADJUSTMENT (COLA) AND QUALITY IMPROVEMENT FUNDING CONSISTENT WITH THE PROVISIONS OF SECTION 640(A)
THEATRE ALLIANCE OF GREATER PHILADELPHIA
This project will be an experimental investigation focused on advancing our understanding of the dynamic behavior of complex fluids (i.e., fluids containing dispersed nanocolloids) in confinement. While the oscillatory equilibrium structure of
Dynamic Properties of Confined Complex Fluids
A better understanding of the behavior of powders is becoming increasingly important as industrial processes require smaller and smaller particle sizes. In addition, there is a growing realization that the existence of fines even in nominally l
FREELY-FALLING GRANULAR POWDER STREAMS AS SENSITIVE PROBES OF INTERPARTICLE FORCES
To support the preservation of jobs that are threatened by declines in philanthropic and other support during the current economic downturn, as described in your application (A09-904395) and the approved project budget.
Collaborative Renewal Proposal:  NSF Center for Friction Stir Processing I/UCRC PROJECT SUMMARY The Center for Friction Stir Processing (CFSP) is a multi-university Industry/University Cooperative Research Center (IUCRC ) established in 2004 wi
Collaborative Renewal Proposal:  NSF Center for Friction Stir Processing I/UCRC
Pollination is an essential ecosystem service that is currently threatened by anthropogenic forces. Through climate change and species invasions, historic plant-pollinator interactions are likely disrupted due to alterations in the abundance, d
RAPID: COMPARING HISTORIC AND CONTEMPORARY PLANT-POLLINATOR INTERACTION NETWORKS TO INVESTIGATE THE EFFECTS
This project is for the continued development of a Helium (He) 1083nm resonance bistatic lidar which will achieve the first lidar measurements of the upper thermosphere. A key element in the lidar design and construction has already been attain
EAGER: Thermospheric Helium (He) Resonance LIDAR Development
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  The Math for America Boston: Teacher Scholars Program represents a partnership among Boston University, seven high needs school districts in the
Math for America Boston: Teaching Scholars Program
L A THEATRE WORKS (A NON-PROFIT CORPORATION)
To Support the preservation of jobs that are theatened by declines in philanthropic and other support during the current economic downturn, as described in your applocation (A09-905679) and the approved project budget.
Art and the American Recovery & Reinvestment Act of 2009.
A plan to prepare in-service STEM Teachers for certification and leadership
This engineering education research award to Purdue University will employ researchers to investigate the role of socioeconomic status in student decision making, academic trajectory, and success using MIDFIELD, a longitudinal database of infor
Socioeconomic Factors in Engineering Pathways
This engineering education research award to Purdue University will employ researchers to develop a conceptual framework for assessing sustainability knowledge gained by undergraduate engineering students and to explore elements of a sustainabi
IEECI:Assessing Sustainability Knowledge (ASK): Development of a Framework to Assess Undergraduate Students' Knowledge of Sustainability Concepts
This engineering education research award to Virginia Polytechnic Institute and State University will employ researchers to combine two types of experiential learning, namely undergraduate research and internships with industry, in a format tha
Synergistic Learning & Inquiry through Characterizing the Environment for Sustainability (SLICES): Improving Understanding of Real World Systems via Direct Observation/Reflection
Collaborative Research: Interactive Knowledge Networks for Engineering Education Research
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5)  This engineering education research award to Northern Illinois University will employ reserchers to develop and assess the effectiveness of a 'min
Creating Minimal Video Games for Engineering Education Research
This award is an outcome of the NSF 09-524 program solicitation 'George E. Brown, Jr. Network for Earthquake Engineering Simulation (NEES) Research (NEESR)' competition and includes the University of Illinois at Urbana-Champaign (lead instituti
NEESR-CR: Hybrid Masonry Seismic Structural Systems
The Long Term Ecological Research (LTER) Network is a group of 26 of the most intensively-studied ecosystems in the world.  Since 1980, the National Science Foundation has sponsored research on long-term ecological processes that determine the
Support and Cyberinfrastructure Development for Integrated Network Science in LTER
This award is an outcome of the NSF 09-524 program solicitation 'George E. Brown, Jr. Network for Earthquake Engineering Simulation (NEES) Research (NEESR)' competition and includes Texas A&M University in College Station, Texas (lead instituti
NEESR-CR: Multi-Scale, Mechanistic Fracture Prediction and Optimal Panel Zone Participation in Steel Moment Frame Buildings
The goal of the Integrated Studies theme of the Ridge 2000 (R2K) Program is to understand the interdependence of component linkages of the mid-ocean ridge system, including the impact of hydrothermal fluid flux on the overlying biological syste
Collaborative Research: Integrating Geological, Chemical and Biological Processes: Implications for Ecological Succession on the East Pacific Rise
The proposed research is directed at developing a manufacturing process for making ultra-sharp bulk metallic glass surgical knife blades as a high-performance low-cost alternative to single-crystal diamond blades. The work will involve developi
EAGER: A Thermally-Assisted Magnetic Flow-Based Process for the Manufacture of Bulk Metallic Glass Surgical Cutting Blades
Intellectual Merit Two major barriers in conventional approaches for converting microalgae to liquid fuels on a large scale are the needs to cultivate algae with high oil content and to dry the algae and extract the oil components. The PIs prop
EFRI-HyBi: The Science and Engineering of Microalgae Hydrothermal Processing
This research investigates the ways that citizens and policy makers attend to stimulus funds under the Recovery Act of 2009. The research develops new methods to estimate the impact of stimulus funds on the perceptions of citizens and the choic
RAPID: Collaborative Research: Recovery Spending and Citizen Expectations
The Center for Ethnomusicology at Columbia University holds valuable recordings of traditional Iupiat (Native Alaskan) music recorded in Barrow, Alaska by collector Laura Boulton in 1946. Co-Pis Fox and Dr. Sakakibara are working with Iupiat co
Community-Partnered Repatriation of Inupiat Music
The plant innate immune system represents an important barrier that pathogens need to circumvent in order to cause disease. It relies on a receptor-based surveillance that detects the presence of conserved molecules of microorganisms outside th
EAGER: Plant Chromatin Remodeling in Response to the Bacteria Pathogen Pseudomonas Syringae
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  There is increasing evidence that iron is important in regulating bulk phytoplankton production in large regions of the world oceans and also inf
Collaborative Research: EAGER: Microfluidic assessment of chemotaxis towards different inorganic and organically complexed iron species by marine bacteria and phytoplankton
Long-term studies of mammals are precious resources for scientists and the public, but rarely are such data sets fully exploited. This is largely because, with volumes of data stored in many formats (e.g. spreadsheets, text, image files), biolo
Multi-Relational Networks In a Large-Brained Social Mammal Through Visual Graph Inquiry
Arts and the American Recovery & Reinvestment Act f 2009
NEW YORK FOUNDATION FOR THE ARTS INC, THE
To support the preservation of jobs threatened by declines in philanthropic and other support during the current economic downturn
The goal of the project ?STCI: Integrated Resource Provisioning Across the National Cyberinfrastructure in Support of Scientific Workloads? is to develop a resource provisioning system that will provide a common job interface to the two nationa
STCI: Integrated Resources Provisioning Across the National Cyberinfrastructure in Support of Scientific Workloads
The University of Arizona is awarded a grant to develop tools that enable biologists to better integrate web data and services. The project has three specific goals. First, it will develop ontologies as the 'currency' of semantic web services.
SSWAP: Simple Semantic Web Architecture and Protocol
Arts and The American Recovery & Reinvestment Act of 2009
MONTGOMERY MUSEUM OF FINE ARTS ASSOCIATION INC
his proposal will be awarded using funds made available by the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  This project will operate a small experimental GPU cluster configured for application physicists and applied math
EAGER: Experimental GPU Cluster for Fundamental Physics
The National Science Foundation provides graduate fellowship support under the Graduate Research Fellowship Program. Potential fellows apply to the National Science Foundation. Outstanding applicants are selected for graduate study leading to r
Office of Research and Project Administration
Graduate Research Fellowship Program that readies GRFP fellows for teaching and science research in the work force.
This award provides $40,500 per student per year in support to 8 graduate students to do research in various STEM (Science, Technology, Engineering and Mathematics) fields as defined in their individual applications to the Graduate Research Fel
Background: Contact networks shaped by social processes are key drivers of epidemic dynamics. Understanding the structure of network formation is thus crucial to our understanding of how human interactions affect the spread of infectious diseas
RAPID: Structure of Contact Networks and the Spread of Flu-like Infectious Diseases:Implications for Dynamics and Control
With this EArly-concept Grants for Exploratory Research (EAGER) proposal, the team aims to demonstrate that BOINC can be an efficient platform for a wide class of applications employing a probabilistic inference based on Gibbs sampling. Specifi
Citizens Science: Enabling Computational Probabilistic Methods for Organism's Transcriptional Regulatory Network Using Voluntary Computing Platforms
This engineering education award to the Syracuse University will develop an innovative model of attracting veterans to engineering study, predicting how many will be likely to study engineering and customizing the degree program to their needs.
From Battlefield to Classroom: Designing Pathways to Engineering for American GIs
Increasing levels of congestion in urban traffic networks have significant economic and environmental impact. Supported by dramatic increases in sensing and communication ability, there is a renewed emphasis on developing intelligent transporta
Early Concept Grant for Exploratory Research (EAGER) Dynamic Traffic Equilibrium Problems: Distributed Alogrithms and Error Analysis
Model-based simulation is a computational approach that enables manufacturing firms to perform virtual prototyping instead of relying exclusively on physical prototyping. Research by the Council on Competitiveness indicates that leveraging cybe
Software Application Discovery Initiative (SADI) Study
Kalaeloa Blvd (RTE 95), Widening and Reconstruction, Phase 1 - OR&L ROW to Lauwiliwili Street
Arts and the American & Reinvestment Act of 2009
Arts and the American Recovery Reinvestment Act of 2009
To support the preservation of jobs threatened by the declines in philanthropic and other support during the current economic downturn.
The objective of this research is to demonstrate the feasibility of reconfigurable wireless interconnection networks operating in the 60 GHz ISM (industrial, scientific and medical) band for data centers and server farms. The approach is to bui
EAGER: Reconfigurable Gigabit Wireless Networks for Data Center Interconnects
Arts and the American Recovery & Reinvestment Act 2009
To support the preservation of jobs that are threatened by declines in philanthropic & other support during the current economic downturn.
The support the preservation of jobs that are threatened by declines in philanthropic and other support during the current economic downturn
Award title: Head Start COLA/Quality Improvement.  COLA - Provides Head Start employees with a temporary 2.02% cost of living adjustment; helps offset a portion of ongoing operational costs not funded by regular Head Start grant.  Quality Impro
ARRA Cost of Living Adjustment (COLA) and a Quality Plan consistent with the provisions of Section 640(5) and 644(a) of the HS Act promoting school readiness.
The purpose of this award is to deploy an intergrated EHR to additional community health centers and Office of Rural Health and Community Care sites and to integrate their care models using that technology.
UNIVERSITY OF MEDICINE AND DENTISTRY OF NJ (INC)
This award supports traineeships for public health students in severe shortage areas of biostatistics, epidemiology and environmental health at the UMDNJ School of Public Health.  It is expected that funds will be expended over two academic yea
AARA-Public Health Traineeship Program funding will bolster by more than 200% the Public Health Traineeship Grant used to secure funding for qualified students demonstrating financial need who are enrolled in the shortage-defined areas of biost
ARRA - Public Health Traineeship Program
Capitol Improvement Project including Health Information Technology Equipment. This is a renovation project to make the facility more energy efficient and to add health information technology.  The project is completed with all upgrades to the
Grant name:  HRSA-ARRA Capital Improvement Program.   This grant provides funding to build a new community health center facility in conjunction with a USDA-Rural Development loan.  The facility will be 10,714 square feet located at 41865 Pomer
NATIVE AMERICAN REHABILITATION ASSOCIATION INC
Project Description: The purpose of developing the new site is to provide a community based center that provides medical care, mental health services and substance abuse treatment in a model that is specifically designed for patients living wit
alternatives and replacement of older sinks in disrepair. ?	Painting/Carpeting - Painting of building interior and carpet replacement to improve interior aesthetics. ?	Security System ? Installation of system for in-house pharmacy, dental buil
AJO COMMUNITY HEALTH CENTER EXPANSION AND RENOVATION PROJECT
HRSA awarded Community Helthlink (CHL) funding for a renovation project and to purchase equipment.  The renovation project improves life safety in the clinic as it provides funding to allow CHL to renovate its building fire escape.  CHL also pl
The CIP Proposal includes two projects, an internal redesign and renovation of our Keller clinic and a purchase and installation of electronic dental records and digital radiography for our dental service in both Inchelium and Keller. The Kelle
PrimeCare Community Health, Inc. proposes to establish a federally qualified community health center in the Chicago community area identified as Portage Park. According to the 2000 U.S. census, Portage Park has a total population of 65,340 of w
Capital Improvement Capital Improvement Program Grant: Construction/Renovation Project Electronic Health Records Project IT/Equipment Project
Project name: Thundermist Health Center Capital Improvement Program   Project goal: To increase access to healthcare by constructing a new, 15,500 sq foot state of the art health center facility in West Warwick, RI.  This project will allow Thu
PRIMARY HEALTH CARE CENTER OF DADE, INC.
ARRA-Capital Improvement Projects.  Primary Health Care Center needs to resolve 3 major problems:  1) the acquisition of electronic medical records and practice management for both Trenton and Rossville GA clinical sites.  Implementation of EHR
The ARRA Capital Improvement Program (CIP) award was given to the Kenosha Community Health Center (KCHC) to improve its physical infrastructure in order to increase access for low income patients. to create jos, and to stimulate the economy dur
ARRA - Capital Improvement Program.  No action taken with this grant during this reporting period.  Grant is in process of close out in order to transfer funds to a different grantee.
The CIP Grant is enabling our Community Health Center to add on an additional 4,000 square feet.  With this addition we will able to bring in specialists to rent the space.  We are looking at bringing on a Dermatologists, Cardiologists (signed
The Capital Improvement Program grant is awarded as part of ARRA in order to enable reinvestment and recovery from the economic recession through the creation or saving of jobs.  The strengthening of capital structure through capital improvemen
The purpose of the Capital Improvement Program is to provide financial support to section 330-funded grantees to implement projects that address immediate and pressing health center facility and equipment needs.
for Federally Qualified Health Centers. The Capital Improvement Program was designed to support construction, rennovation and equipment, and the aquisition of health information technology systems for federally qualified health centers.
COMMUNITY HEALTH & WELLNESS CENTER OF GREATER TORRINGTON, INC
Recognizing the severe inadequacy of dental services in northwestern Connecticut, the CHWC has designed a 3,200 sq. ft. dental suite which can accommodate six chairs, one dentist, two full-time hygienists, a part-time hygienist and a receptioni
Two of the most important abstractions in Computer Science are graphs and point clouds. A graph abstracts relations between things: two vertices in a graph are connected by an edge if the objects associated with the vertices are related. Direct
AF: small spectral graph theory, point clouds, and linear equation solvers
MGH INSTITUTE OF HEALTH PROFESSIONS, INC.THE
The ARRA-NFLP funding has provided funding to five doctoral students planning to become nurse faculty who are entering the nursing education workforce and thus further alleviating the nursing faculty shortage.  Funding enables these students to
Samford University utilizes the American Recovery Reinvestment Act (ARRA) funds available to the Nursing Faculty Loan Program (NFLP) to support students enrolled in the Ida V. Moffet School of Nursing's advanced education nursing programs: MSN
This New Access Point Grant will permit a major expansion of health care services including primary care, dental care, and mental health care in Citrus County Florida.  The goal is to significantly increase capacity to provide acute care for mi
Recovery Act Health Center Cluster Program - Citrus County
Like other underserved populations of color, Dale District residents face a daunting array of cultural and economic barriers to appropriate health care. Almost two in five, 37%, of all Dale District residents are uninsured, while 60% of low-inc
GREATER PRINCE WILLIAM COMMUNITY HEALTH CENTER, INC.
The Greater Prince William area has experienced record job losses, a 50% decline in housing values and a rate of home foreclosures far greater than the state average and the metropolitan Washington area. The federal estimates from 2005 indicate
CENTRO DE SALUD DE LA COMUNIDAD DE SAN YSIDRO, INC.
To establish a New Access Point(NAP)Clinic in support of a new site and service area originally submitted in response to HRSA-08-077.
Recovery Act Health Center Cluster Program- New Access Point(NAP)
BOWLING GREEN-WARREN COUNTY PRIMARY CARE CENTER, INC.
ARRA-Increase Demand for Services Health Center Cluster These funds allowed for the retention of staff that would have been laid off as well as hire new staff for the expressed purpose of seeing more uninsured and Medicaid patients. Hiring an a
ARRA-Increased Demand for Services to Health Center  The purpose of the proposed project is intended to increase provider capacity to address the unmet need that exists in the three of La Casa?s four county service areas.   The goals are as fol
ARRA - Increased Demand for Services (IDS) will allow GPHA to increase service capacity and expand access in the following areas: 1)Comprehensive primary care pediatrics, 2)Preventive and restorative dental services for pediatric patients from
NATIVE HEALTH was awarded two years of funding to address ?Increased Demand for Services? relative to the poor economy and job losses.  NATIVE HEALTH had been previously funded to initiate a New Access Point Community Health Center a few months
Increased Demand for Services (IDS) Project Grant The Osceola County Health Department (OCHD) will increase patient access to primary care services through extended hours clinics offered at two sites on Saturdays. This will allow patients to ac
ARRA - Increase Services to Health Centers - Osceola County
Purpose:  Hire additional support staff  to support an Increased Demand for Services at Monroe Health Center.   Goals:  Hire a billing clerk, intake/triage specialist, medical records clerk(s), CNA, and radiologic technologist.   Adding the a
Purpose of this grant is to promote child health to infants and young children by providing screening and assessing children in Maniilaq Service Area at clinics to perform periodic physicals and developmental screening and to refer children to
ARRA Increase Services to Health Centers
COMMUNITY HEALTH CENTERS OF THE RUTLAND REGION
CHCRR projects the increased acute care capacity at Castleton Family Health Center that will be created by this project will provide a minimum of 3,276 visits to 491 new CHCRR patients drawn from all the service areas of the 3 CHCRR medical cli
The Greater Prince William Community health Center provides comprehensive primary health care services. Survey data on the uninsrued, the primary target population GPWCHC serves, shows that approximately 47,000 persons in the Prince William Hea
PHMC received an Increased Demand for Services grant for its 3 Federally Qualified Health Centers.  PHMC's goals are to add evening and weekend hours in order to serve more patients; hire a nurse to see homeless patients at low demand shelters;
ARRA - Increased Services to Health Center
With IDS funds, HHC has expanded its hours of operation at its main medical site, effective June 1, 2009. The new hours of operation are by department as follows: ADULT MEDICINE: Mon 7:30AM to 6:30PM; Tues-Thurs 7:30AM to 8:00PM; and Fri 8:00AM
Increase Services to Health Centers - Duval County.  This grant supports expanded primary care clinical operations on Saturdays. The average number of patient visits at the Saturday clinic was 21 for the quarter ending this reporting period. Ro
ARRA - Increase Services to Health Centers - Duval County
Increase Services to Health Centers - Palm Beach County  The grant supports additional health care staff at a major primary care safety net clinic site in Palm Beach County.  Staff include physicians, nurses, and support staff. This supports th
ARRA - Increase Services to Health Centers - Palm Beach County
G.A. CARMICHAEL FAMILY HEALTH CENTER, INC.
ARRA funding was awarded to G.A. Carmichael Family Health Center in order to retain the services of two physicians with over fifty years of combined experience providing medical care in the communities served by the health center.  It has also
The stated purpose of this award was to provide support for increased demand for services caused by the downturn in the economy, the assumption being that bad economic times creates additional demand because there are more low income persons. I
ARRA-Health Center Integrated Services Development.THE PURPOSE OF THIS AWARD IS TO EXPAND ACCESS TO NEEDED PRIMARY HEALTH CARE SERVICES, MEDICAL AND DENTAL, SPECIFICALLY BY EXPANDING SERVICES AT EXISTING HEALTH CENTER SITES FOR THE UNDERSERVED
ARRA - Health Center Integrated Services. This grant funded the restoration of wage/hour cuts that all staff took during January 2009.  A portion has been used each month to fund restoration of those wages.  No raises have been given to any sta
The Yale Program in Cellular Neuroscience, Neurodegeneration and Repair (CNNR) was co-founded by the PI and Co-PI four years ago with the goal of linking basic research in neuronal cell biology with efforts to advance pathophysiological underst
Yale Cellular Neuroscinece neurodegeneration and repair (CNNR) Program
HEBREW REHABILITATION CENTER FOR AGED, INC.
This award supports the renewal of the Harvard Older Americans Independence Center (OAIC), which was previously funded from 1991-2006. Over this period the Center generated 928 research papers and trained over 50 new investigators in the field
Harvard Older Americans Independence Center Grant
Over the next several years, the number of older individuals in the U.S. population will increase dramatically.  Associated with this aging population, will be a large surge in the number of cases of age-associated illnesses.  Understanding the
Dissecting complex regulation by C. elegans DAF-16
Mental and physical functioning have major implications for the quality of life of older individuals. We plan to examine a largely unexplored social psychological factor that may benefit older individuals longterm functioning: the age stereotyp
Positive Age Sterotypes Across the Life Span
Rheumatoid arthritis is a chronic inflammatory disease of diarthrodial joints. This systemic disease is characterized by chronic synovitis, sustained by an antigen-driven immune process against one or more proteins found in cartilage. Although
Suppression of Collagen Induced Arthritis with Altered Peptide Ligands
Treatment of breast cancer with hormonal therapy and more recently trastuzumab (Herceptin) has led the field of cancer treatment in the use of companion diagnostics to select patients most likely to respond to targeted therapies. However, the c
Optimal Predictors of Response to Trastuzumab
Emotion Regulation and Depression in Breast Cancer Survivorship:  Both in individuals living with cancer and in the general population, the experience of clinical depression exacts a profound psychological, physical, and economic toll. Little r
EMOTION REGULATION AND DEPRESSION IN BREAST CANCER SURVIVORSHIP
The homeostatic balance between proliferation and apoptosis is essential for the intestinal epithelium to function as a physiological and structural barrier. Intestinal epithelial cells have a high rate of cell turnover accompanied by an equall
Regulation of Epithelial Cell Homeostasis by Actin Microfilaments
The proposed studies of redox sites in photosystem II address fundamental aspects of catalysis that are ubiquitous in metabolic mechanisms of metalloenzymes common to different classes of organisms from bacteria to humans (e.g., P-450s, peroxid
Studies of Redox-active sites in photosystem II
Title: - p63-Dependent Checkpoints in Oocytes.- This project is to define at the molecular level a mechanism that prevents birth defects. In brief, we have discovered a female-specific quality control process operating directly in oocytes that
Adolescent Health Literacy: Improving Use of Preventive Health Services in order to to enhance adolescent health literacy, increasing teens 'capacity to access and use their insurance and the current health care system, so they can become empow
ADOLESCENT HEALTH LITERACY: IMPROVING USE OF PREVENTIVE HEALTH SERVICES
JAMAICA CENTER FOR ARTS AND LEARNING, INC
To support the preservation of  jobs that are threatened by declines in philanthropic and other support during the current economic downturn
To support the preservation of jobs that are threatened by declines in philanthropic and other support during the current economic downturn, as described in application A09-905722 and the approved project budget.
Arts and the American Recovery & Renivestment Act of 2009
This project will digitize and provide internet access to over 2000 Alaska Native language interview tapesrecorded under the 1971 Alaska Native Claims Settlement Act and another 2000 plus recordings selected from the 5000 held by the Alaska Nat
Alaska Native Language and Oral History Digital Audio Resources
NATIONAL ASSEMBLY OF STATE ARTS AGENCIES
The purpose of this award is to support the preservation of jobs that are threatened by declines in philanthropic and other support during the current economic downturn.
CULTURAL RESOURCES, NEW HAMPSHIRE DEPARTMENT OF
To support the preservation of jobs that are threatened by declines in philanthropic and other support during the current economic downturn, as described in my application A09-904736 and the approved project budget.
To support the perservation of jobs that are threatened by declines in philanthropic and other support during the current economic downturn.
ARRA provided funding for Congregate Nutrition Services.  Established in 1972 under the Older American Act, the program provides meals to older Americans in congregate facilities such as center centers, adult day centers, and faith-based settin
ARRA provided funding for Home Delivered Nutrition Services. Established in 1978 under the Older Americans Act, the program provides meals to older Americans who are homebound.
ARRA Home-Delivered Nutrition Services- 2009 T3C2_ARRA
ARRA provided funding for congregate nutrition services.  Established in 1972 under the Older American Act, the program provides meals for older americans in congregrate facilities such as seniors centers, adult day care centers,and faith based
Well balanced meals provided to eligible homebound older persons five days a week, including designated holidays and emergencies when congregate meal sites are closed.  Participants enjoy a measure of socialization from their delivery person(s)
ARRA Home Delivered Nutrition Services for States - Provide grants to States to support nutrition services including nutritious meals, nutritious education and other appropriate nutrition services for Older Americans in order to maintain health
American Recovery and Reinvestment Act of 2009 Grant for Home-Delivered Nutrition Services.  Grant funding will be used to stabilize State and local government budgets, in order to minimize and avoid reductions in essential services and counter
OFICINA DEL GOBERNADOR PARA ASUNTOS DE LA VEJEZ
ARRA provided funding for Home-Delivered Nutrition Services. Established in 1978 under the Older Americans Act, the program provides meals to seniors who are homebound.
SOCIAL AND HEALTH SERVICES, WASHINGTON STATE DEPARTMENT OF
SENIOR SERVICES, WEST VIRGINIA BUREAU OF
ARRA provided funding for Congregate Nutrition Services. Established in 1972 under the Older Americans Act, the program provides meals to older Americans in congregate facilities such as senior centers, adult day centers, and faith based settin
ARRA provided funding for Home Delivered Meals.  This funding is used for the production and distribution of shelf stable emergency meals for older adults eligible under the same criteria as Title III-C2 of the Older Americans Act.
Chignik Lake and Port Heiden Housing Development
Installation of 17 energy efficient roofs and insulation will result in reduced energy consumption and cost savings to residents; installation of energy efficient heat pumps in 37 low income units and removal of existing systems will result in
Energy Efficient Housing Rehabilitation NAHBG
KEWEENAW BAY OJIBWA HOUSING AUTHORITY INC
Native American Housing Block Grant, Competitve - NAHASDA - eligible activities including new construction of affordable homes for purchase by low-income tribal members.
CHOCTAW HOUSING AUTHORITY LIMITED PARTNERSHIP 1
Development of 32 Rental Units at Frog Level Subdivision (Tiak Chitto)
Native American Housing Block Grant-Competitive- NAHASDA-Intrastructure and Administration
Wastewater Treatment, Water, Street and homesite Infrastructure Development
Sicangu Village Subdivision Expansion Infrastructure
CHA Green Rehablilitation. CHA will rehab approximately 191 low rent units.
The Southwest Conservation Corps (SCC) will employ Veterans to complete trail restoration projects across lands within the US Forest Service, Rio Grande National Forest, over the next 26 months.  The primary work activity will be restoration of
MARGRET AND HA REY CENTER & THE CURIOUS GEORGE COTTAGE
The purpose of this Challenge Cost Share Agreement is to support a collaborative working relationship between the Margret and H.A, Rey Center and the United States Forest Service through trail reconstruction work on Welch-Dickey and Sandwich Mo
Forest Service Recovery Act Agreement Number: 09-CS-11094419-007 between Margret and H.A. Rey Center and United States Forest Service, Region 9, White Mountain National Forest, Pemigewasset Ranger District.
Native American Housing Block Grant,Competitive-NAHASDA-eligible activities including acquisition, new construction, rehabilitation of affordable housing, site improvement, development and rehabilitation of utilities and infrastructure, utility
Development of Single Family Homes For Tribal Elders
Native American Housing Block Grant, Competitive--NAHASDA__eligible activities including acquistion, new construction, rehabilitation of affordable housing, site improvement, development and rehabilitation of utilities and infrastructure, utili
Construction of two (2) senior duplexes and construction of twelve (12) single family units
This project was awarded on August 24, 2009 and calls for energy audits and rehabilitation of 100 Oneida Housing Authority rental units. The project name is Oneida Rental Energy Efficiency Project (OREEP)
Native American Housing Block Grant, Competitive - NAHASDA-eligible activities including acquisition, new construction, rehabilitation of affordable housing, site improvement, development and rehabilitation of utilities and infratstructure, uti
There are two subprograms: Flathead Forest Stewardship ($897,500) & Energy Conservation Landscaping ($89,500). The Flathead Forest Stewardship Grant will provide forest restoration & wildfire fuels hazard reduction treatments to forested state
Flathead County Stewardship/Energy Conservation Landscaping
Community Wildfire Protection Plans bring neighboring landowners together to assess current wildfire risks associated with topography, the amount of dead and live fuels available to a fire, and probable ignition sources. The landowners (who may
FOOD & AGRICULTURE, CALIFORNIA DEPARTMENT OF
A partnership with the U.S. Forest Service to survey, map, document, treat and eradicate A and B Rated Invasive weed populations.  In partnership with the already established  weed management areas to maintain and protect affected areas near an
ARRA Distressed Weed Management Area Grants
These projects are intended to enhance the health, vigor, productivity and sustainability of State Forest lands in Oregon, and also prevent, contain and control invasive plants on those lands. This will be accomplished by pre-commercial thinnin
This project seeks to reduce or eliminate the potential for introduction, establishment and spread of invasive species, which displace and compete with native species.  This project will assist small forestland owners with identification and tr
Non-Industrial Landowner Noxious Seed Abatement
The desired outcome of these projects is to reduce the risk of catastrophic wildfire in high risk communities in Skamania County, through a coordinated effort of fuels reduction projects across private and state lands within the wildland urban
West Skamania County Community Wildfire Protection Plan Fuel Break
This project will restore approximately 15 acres of coastal prairie habitat to benefit the threatened Oregon silverspot butterfly (Speyeria zerene hippolyta) on private property at Big Creek adjacent to habitat on National Forest lands between
Big Creek Oregon Silverspot Ecosystem Restoration Project
The Florida Department of Agriculture and Consumer Services, Division of Forestry will contract for mechanical fuel reduction in areas of high wildfire risk throughout Florida, strategically placed to provide protection to thousands of resident
Florida Community Fuels Management Program Phase I
This project will continue efforts by landowners adjacent to the Okefenokee Wildlife Refuge to create a wildfire resilient buffer surrounding the Okefenokee Swamp. Efforts will include forest fuel reduction techniques and forest management prac
Enhanced Fuels Management/Community Wildfire Protection Plans
This project will expand the current cogongrass education, detection, and eradication efforts by working through the cogongrass task force. State-owned lands will be surveyed and treated for high-priority invasive plant species. Incentive payme
Cogongrass & Invasive Species Eradication
Woody biomass grant for pre-construction permitting & equipment in preparation of a biomass densification plant to be built in Cass County MN.  The plant will use excess biomass from loggers to manufacture renewable energy products such as wood
DB East Energy, LLC/Woody Biomass (Bellerud Forest to Energy)
Hazardous fuels reductions, forest health protection, rehabilitation and hazard mitigration activities on Federal lands, State and private forestry activities including hazardous fuels reductions, forest health and ecosystem improvement activit
Prescribed Fire Project for Puertorrican State and Private Forest land
The primary purpose of this initiative is to create and oversee the conversion of at least 15 public buildings to wood or dual fuel heating, and promote sustainable management of forest land. In addition to creating and maintaining jobs, this i
This project focuses resources on eliminating or dramatically reducing the impact of invasive plant species that have negative effects on forest health in Rhode Island. This project targets certain species that are still in the early detection
Invasive Vegetation Survey and Eradication
2.3 Mi E TH 74 to 0.5 Mi W TH 43 WB Lanes, Bituminous Overlay
Silver Cliff Tunnel and Lafayette Bluff Tunnels N of Two Harbors, Skid Treatment
3.7 Mi S of Jct TH 210 (Atkinson BR 09823 and 24), Living Snow Fence
Remove bridges 04003 & 04004 (over abandoned railroad track) 0.5 Mi W of Jct TH 89 (RP 107.3 to 108.1) Lowering grade to improve safety.
State Entry Sign Location Landscape Rehabilitation at Beaver Creek
Replace Existing B 29509 on CSAH 9 Over the Schoolcraft River with New BR 29529 and Approach Grading and Bituminous Surfacing
Replace BR 7083 and Approach Grading at N Branch of Two Rivers, 5 Mi N of Hallock
Replace BR 7103 Over Lac Qui Parle River, Approach grading and surfacing
Clearwater CSAH 4 to the Red Lake Reservation Line, Resurfacing
Our preliminary data indicate ischemic hearts from rats have a transient decrease in protein phosphatase 2a (PP2a) activity, and an increase in phosphorylation of phospholamban, ERK and AKT. The decrease in PP2a activity occurs concomitant with
Myocardial Ischemia-Reperfusion and Protein Phosphatase 2a
Obesity and obesity related medical conditions contribute to increased mortality among persons with schizophrenia and increased healthcare costs. There are no treatments that have been convincingly shown to be effective for weight reduction in
Lifestyle modification to reduce weight and related morbidity in mental illness
Anti-retroviral therapy (ART) for human immunodeficiency virus (HIV)-1 infection has prolonged and improved quality and longevity of life. Nonetheless, disease morbidities associated with HIV abound, including cognitive dysfunction (HIV associa
In Vivo Reconstitution Models for NeuroAIDS and Beta-Amyloidosis - Biomedical Research
Canonical Transient Receptor Potential Channels and Excitotoxicity Description: The neuronal cell death caused by over exposure to a neurotransmitter called glutamate is a shared event in several neurological diseases, such as epilepsy, stroke
Canonical Transient Receptor Potential Channels and Excitotoxicity
Vascular cognitive impairment is highly prevalent, yet its biological basis has not been well studied. The goal of this proposal is to elucidate the molecular and cellular pathological processes underlying retinal vasculopathy with cerebral leu
PATHOBIOLOGY OF RETINAL VASCULOPATHY WITH CEREBRAL LEUKODYSTROPHY
UNIVERSITY OF KANSAS CENTER FOR RESEARCH, INC.
Chlamydiae infections have an immense impact of public health causing sterility, blindness, pneumonia, and correlated with formation of atherosclerotic lesions and heart disease. These obligate intracellular bacteria are perpetuated through a d
Structural Analysis of a Virulence Gene Regulator in Chlamydia
This research investigates the role of young children's attitudes toward privilege in the development and maintenance of social group attitudes including social class and racial attitudes. There is now considerable evidence that experienced and
The Emergence and Development of Social Group Attitudes
The objective of our project is to study the effect of mild (30%) maternal nutrient restriction on fetal adipogenesis in different fat depots [omental (intra-abdominal), subcutaneous abdominal (subcutaneous upper-body) and femoral (subcutaneous
Poor nutrition and fetal development: preadipocyte adaptation in a primate model
An important component of treatment development for destructive behavior involves the identification of effective reinforcers. Functional analysis is one method of identifying the reinforcer that maintains destructive behavior. Identifying the
Efficacy of Various Positive Reinforcers in the Treatment of Destructive Behavior
Currently 5FU/LV/oxaliplatin (FOLFOX) is the most commonly used therapeutic agent for colorectal cancer (CRC) treatment (Rx). The anti-tumor activity of FOLFOX depends on its ability to induce apoptosis by damaging the DNA and by altering the e
PREDICTIVE MOLECULAR MARKERS OF COLORECTAL CANCER
Memory is probably one of the most widely studied neuronal phenomena since it is required for all living organisms to function efficiently in known and unknown environments. It has recently been proposed that impairment of memory formation in h
Synaptic plasticity, EtOH and backpropagating action potentials in NAcc
Alcohol intoxication is the greatest contributing factor to transportation fatalities in the United States. Alcohol's (EtOH) major pharmacological target is GABAA receptors (GABAAR). The goal of our research is to develop novel anti-alcohol dru
MECHANISMS UNDERLYING THE THERAPEUTIC EFFECTS OF HOVENIA-DIHYDROMYRICETIN ON ALCOHOL INTOXICATION
Generation of FAH-HCV constructs and synthesis of FAH-HCV libraries (Aims 1 and 2) We performed quality control of our mutagenized libraries based on the shuttle vectors pRS-FAH:Con1 and pRS-FAH:HCV-J6/JFH1 to confirm that our clones have on av
Directed Evolution of a Murine Model of Hepatitis C Virus Replication
Title: High throughput screens for modulations of inflammatory cytokine gene expression.  Abstract: Inflammation can be beneficial for a normal immune response to microbial pathogens.  However, prolonged inflammation can promote tissue damage d
HIGH THROUGHPUT SCREENS FOR MODULATORS OF INFLAMMATORY CYTAKINE GENE EXPRESSION
Cellular restriction of HIV infection in host cells reflects innate antiviral immunity. Monocytes are important immune sentinels and precursors of antigen presenting cells. Undifferentiated human monocytes are resistant to HIV infection despite
Exploring Postentry Restriction of HIV Infection in Human Monocytes
TRIM5alpha(Tripartite motif-containing protein 5)proteins bind retroviral capsids after cell entry and restrict retroviral infection by blocking reverse transcription and/or integration of the viral genetic material {Nisole, 2005 #305; Towers,
Structural Basis of Retroviral Restriction by TRIM5alpha
Age-related macular degeneration is the predominant cause of vision loss in adults over 65. Lack of effective treatment stems from both the complexity of the disease, and lack of good animal models in which to study it. This proposal offers the
Eye Diseases, Blindness & Vision Impairments Research
The neurotransmitter serotonin plays an important role in the development of depression. Serotonin is one of the brain's natural chemicals. Serotonin binds to serotonin receptors (binding sites) type 1B on brain cells to regulate emotion, anxie
Serotinin 1B receptor imaging in major depressive disorder
The goal of this proposal is to examine how impairments and alterations in trafficking and targeting of lipid droplets (LD) to specific organelles influences LD accumulation in steatosis and contributes to alcohol-induced fatty liver disease (A
Regulation of Alcohol-induced Fatty Liver Disease by Lipid Droplet Trafficking
We seek to build a molecular classifier based on genetic, genomic, and  imaging data from patients with neurodegenerative dementia. Genetic data will consist of SNP data collected across the genome; genomic data will consist of gene expression
GENETIC, GENOMIC, AND IMAGING BIOMARKERS IN DEGENERATIVE DEMENTIA
We will use state-of-the-art metagenomic approaches to study the microbiome of the widespread human disease, chronic periodontitis. There is almost no information about the microbial community of this disease at the metagenomic level. The Human
MOLECULAR SIGNATURES OF THE PERIODONTITIS METAGENOME
It is known that, in addition to genetic susceptibility in many diseases, environmental factors play a critical role in determining whether susceptible individuals develop the disease. However, it is not clear what these environmental factors a
Effect of Diet and Commensal bacteria on diabetes outcome in NOD mouse
Imaging Strategies to Measure Brown Fat and it's Activity - Obesity results from an imbalance between energy intake and energy expenditure. In obesity these excess calories are stored in white adipose tissue (WAT) depots that are distributed th
Imaging Strategies to Measure Brown Fat and it's Activity
Abdominal Colpopexy: Comparison of Endoscopic Surgical Strategies  Objectives:  The objective of this study is to compare costs and short-term outcomes of laparoscopic and robotic- assisted abdominal sacrocolpopexy (ASC) with respect to patient
COMPARATIVE EFFICACY OF ROBOTIC VS OPEN SACROCOLPOPEXY FOR VAGINAL VAULT PROLAPSE
For two years, four investigators will each hire a new full-time employee to identify and validate a novel therapeutic strategy for a group of rare inherited metabolic disorders, the Congenital Disorders of Glycosylation-Type I (CDG-I). These d
Testing Substrate-Flux Therapies for Glycosylation Disorders using Zebrafish
Performance Indices of Social Disability in Toddlers with Autism' - addresses Challenge Area '(04) Clinical Research' and Specific Challenge Topic 'Autism: Addressing the Challenge (04-MH-101*)'; and Challenge Area '(01) Behavior, Behavioral Ch
Performance indices of social disability in toddlers with autism
Dysfunction of GABAergic interneurons of the cerebral cortex has been implicated in a variety of major  neuropsychiatric illnesses, including schizophrenia, autism, anxiety, and epilepsy (where depression is a major source of suffering). Howeve
Derivation of cerebral cortical GABAergic interneurons from human iPS cells
Our award captures the challenge area (06) 'Enabling Technologies,' to address the specific challenge topic 06-AG-101 Neuroscience Blueprint: Development of non-invasive imaging approaches or technologies that directly assess neural activity. T
A STEM MICROSCOPE FOR HIGH-SPEED 2-PHOTON CALCIUM IMAGING
Asthma is characterized by chronic airway inflammation. It is well established that Th2 inflammation and the downstream responses that occur provide much of the underlying basis of asthma pathogenesis. The biologic function of Th2 inflammation
Understanding the Role of AMCase in Asthma
Purpose:  To aquire state-of-the art flow cytometer.  Abstract:  Our research at  Baylor College of Medicine requiring a four-laser LSRII flow cytometer will specifically study processes within cells allowing us to better understand stem cell t
ST. FRANCIS MEDICAL CENTER OF LYNWOOD DEVELOPMENT CORPORATION
The funding will support St. Francis Career College's Licensed Vocational Nurse program as we mitigate the educational and employment vulnerabilities facing residents of Southeast Los Angeles while concurrently addressing the shortage of health
ARRA- Scholarships for disadvantaged students.
UNIVERSITY OF THE SCIENCES IN PHILADELPHIA
Scholarships for Disadvantaged Students awarded under the American Recovery and Reinvestment Act of 2009 will assist additional students with their program of study in specific healthcare fields.  These funds will assist students in Pharmacy, S
ARRA - Scholarships for Disadvantaged Students
The sensor will be used in diagnostic laboratories and public health facilities.  It will mitigate the effect of a biological attack by providing early detection and verification of intoxication by botulinum and many othe biological agents.
rapid detection of botulinum toxins using a high sensitivity botulinum sensor
RAVALLI COUNTY ECONOMIC DEVELOPMENT AUTHORITY
Funds will be used to provide technical assistance to create a strategic marketing plan and for certifying two projected new hires and two exising employees through the North American Board of Certified Energy Practitioners (NABCEP).
Power and Communication Line and Related Structures Construction
Highway Infrastructure Investment Grant: Highway Surface Transportation and Technology Training
The purpose of this mod is to add additional funding for energy renovation work for Office Row Housing on Midway Atoll.
The work effort included design and preparation of construction documents for a new, appropriately sized chiller dedicated to egg incubation at the Kooskia Hatchery.  Additional work elements included the rehabilitation of other system componen
Provide planning, design and construction services in accordance with USFWS Region 1 & 8 General Engineering Requirements, as further defined and expanded upon in the solicitation and its amendments, to repair or replace, as needed, the main el
design build of new storage barn at Steigerwald National Wildlife Refuge.  Project also includes new gravel road and demo of old storage building. Award amount increased due to change order.
ENGINEERING SCIENCE & CONSTRUCTION L.L.C.
This award is for the design of refurbishing of Page Springs Dam at Malheur NWR.  The refurbishment includes design of new automatic control panels.
Engineering Project Manager - assist engineering staff in managing construction projects under the American Recovery and Reinvestment Act of 2009.
Bismarck - 9th Street from Bismarck Expressway to Boulevard Avenue
I 94 - From County Line TO E Dawson Interchange
TH 2 from the Jct of St Louis Co Rd 845 to Jct St Louis Co Rd 875, Mill & Overlay, Drainage Repairs
Reconstruct County Road D from Flandrau Street to White Bear Ave
Head Start 2009 ARRA COLA Quality Improvement Funding:  Funds were approved to provide a temporary 5% salary increase to program employees, as well as some temporary increases based on merit. Some funds were also set aside to help cover the cos
The award title is Head Start 2009 ARRA COLA (COLA)& Quality Improvement (QI)Funding. The purpose of the COLA portion awards funds to the existing Head Start program to pay for staff salaries over the 12-month period following the effective dat
Head Start 2009 ARRA COLA Quality Improvement Funding.  United Community Action Network Head Start program is a Federal and State Grant funded program partnering with families and communities to provide comprehensive developemental services to
ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act.  This Award provides a half-time Quality Improvement Teacher position.  Quality improvement funds
This award provides for ARRA cost of living Adjustment (COLA) and Quality Improvement Funding consistent with the provisions of Section640 (a)(5) of the Head Start Act for the Head Start program.  Head Start promotes the school readiness of low
This funding will provide a cost-of-living increase of 1.84% for Head Start and the Early Head Start program. Improvements in quality will include training wages, wages for an Infant Toddler Specialist and an Assistant Childcare Billing Special
This grant awards a cost-of-living adjustment (COLA) increase of 1.84% in the amount of $35,649 for Head Start and $6,517 for Early Head Start. These funds must be oblicated to pay for staff salaries over the 12-month period following the effec
CHELAN-DOUGLAS COUNTY CHILD SERVICES ASSOCIATION
ARRA Cost of living And quality improvement funding consistent with the provisions of section 640(a)(5) of the Head Start Act. Children Served:276 Program Options: Center Base and Home Base Area Served: Chelan and Douglas Counties
FY 09 ARRA COLA/Quality for ESD 113 Head Start served 691 preschool children in center based classrooms in Grays Harbor, Mason, and Thurston counties in Washington.  Purpose: provide staff 1.84% COLA, training in curriculum, payment of college
Head Start 2009 ARRA COLA Quality Improvements
This action awards a cost-of-living adjustment (COLA) increase of 1.84% in the amount of $80,607 for Head Start.  These funds must be obligated to pay for staff salaries over the 12-month period following the effective date of this grant ( 7/1/
The funding provided a Cost of Living Adjustment (COLA) increase of 1.84% for Head Start and Early Head Start which will be used to pay for an increase in staff salaries over the 12 month period following the grant award date.  Additional fundi
This award provides ARRA Cost of Living (COLA) and Quality Improvement funding consistent with the provisions of section 640(a) of the Head Start Act. Head Start promotes school readiness of high risk, low-income children through the provision
EWU Early Head Start reviewed its recently completed FY2009 Technical Assistance and Training Plan and looked for opportunities to enhance those activities in a way that would permanently increase the capacity of the organization to provide hig
ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act.  Mountain States Early Head Start (MSEHS) serves 113 pregnant women, infants and toddlers up to ag
This award provides for ARRA Head Start Expansion funding to serve 40 children in a center based (classroom) environment. The Head Start program provides child care and family services for low-income families with children ages of 3-5 years.  T
Grant for nursing home improvements and repairs
INCLINE VILLAGE GENERAL IMPROVEMENT DISTRICT
HDPE pipe for purpose of exporting treated wastewater effluent.  Segment 5 is located in the Carson Valley of Nevada and runs near the banks of the Carson River.
Rocky Hill;  Old Main Street Pavement Rehabilitation
South Windsor;  Buckland Road Pavement Rehabilitation
Fish Lake Interchange to Henn/Wright Co Line-Rebuild Cable Median Barrier
The primary purpose of this Cooperative Fire Protection Agreement is to maintain firefighting capacity in southern Oregon in the face of pending layoffs by Josephine County of their fire fighting personnel.  This capacity will be maintained by
Cooperative Protection Agreement between Josephine County Department of Forestry and USDA Forest Service, Rogue River-Siskiyou National Forest
The research conducted under this Joint Venture Agreement (JVA) with the USFS Pacific Northwest Research Station will be supported from the American Reinvestment and Recovery Act (ARRA) funds.  The goal of this JVA is to create or retain jobs i
Integration of Fuels, Fires and Vegetation Software Tools to Improve Assessments of Landscape Scale Fire Hazard
Biochar pellets will be produced to determine their efficacy as a soil amendment in forestry recovery operations. Biochar from forest slash pyrolysis will be obtain from a commercial supplier and sent to the Composite Materials and Engineering
Using Fast-pyrolysis Biochar to Develop Pellets for Application to Forest Soils
Composite Materials and Engineering Center
Reducing the threat of catastrophic wildfire to communities and the forest while improving forest health, repairing trails and trailheads.
BCCC Trails-Shasta Trinity NF - Jobs Partnership and Community Wildfire Protection Project
ARRA-Youth Employment Program/Fuels Reduction, as project under Reducing Threat of Wildfires in Central and Southwest Oregon. To provide youth and young adults, ages 16-24 with meaningful work experience designed to foster the growth of skills
ARRA-Summer Youth Employment Program/Fuels Reduction, a project under Reducing Threat of Wildfires in Central and Southwest Oregon.
The purpose of the program is to assist with building the dignity and self-worth of the ever growing numbers of tribal families in need of assistance.  By helping the families to maintain an essential standard of living and providing them with
CHILD CARE AND DEVELP0MENT FUND STIMULUS - FOR LOW INCOME FAMILIES
ARRA CSBG 2009 Tanana Chiefs Conference Tribal Development Community Planner & Economic Development Project.  Award Use: Training in TCC Six-Subregions in Interior Alaska for Tribal members.  Training will focus on Community Planning, Financial
TCC ARRA CSBG Community & Economic Development
the award represents an additional discretionary fund obligation to the tribe for fiscal year 2009
Child Care and Development Fund Stimulus funding will be used to: 1) collaborate with Laguna Early Head Start program to renovate a modular building to provide full-day, full year center-based early childhood services for 16 additional infants
AmeriCorps funding will deploy 40 members to serve as community health advocates.
Community volunteers will be recruited and managed to address conservation and land management needs in their communities. $239,319 will be used as match replacement funds.
The purpose of this award is to assist the grantee in carrying out a national service program as authorized by the National and Community Service Act of 1990, as amended (42 U.S.C. §12501 et seq.) and in the American Recovery and Rein vestment
City Year Chicago  AmeriCorps members will assist at risk students by providing tutoring and literary services.  The City Year Members will serve clients with their tutoring and literary services.  AmeriCorps members from Public Allies Chicago
Recovery IL Commission on Volunteerism &Community Svc
LABOR & INDUSTRY, PENNSYLVANIA DEPARTMENT OF
Award supports AmeriCorps members who focus on providing mentoring and academic support to youth and assisting a wide variety of local non-profit agencies to meet increased demand for services during economic downturn.
AmeriCorps members will be assisting in classrooms as literacy tutors and will be working with project sponsors on conservation projects across the state.
AmeriCorps members focus on financial literacy, health care access and developing professionals through service.
ECONOMIC DEVELOPMENT, MISSOURI DEPARTMENT OF
This award funds the approved ARRA AmeriCorps formula programs that focuses on activities related to housing and senior assistance, employment and skills training, and tutoring.
AmeriCorps State Formula Members will:  Recruit new volunteers and increase volunteer time at the youth center Warehouse and will recruit new long-term volunteers.   Provide job counseling and skills training (youth employment services) to at-r
AmeriCorps members assisted various school districts, city agencies, and a non-profit agency in providing tutoring, mentoring, after-school programs, volunteer recruitment, and housing rehabilitation in low-income communities.  Success was meas
Award focuses on tutoring and literacy services and improved academic success for grades K-12; capacity building services for health care related activities in nonprofit agencies; and recruiting volunteers to address needs in their communities.
WI National and Community Service Board - Recovery Formula
NCLR expanded its AmeriCorps program to address the impact of the economic downturn on the Latino community.  AmeriCorps Members will provide job training services to clients affected by the economic downturn.  This will include leading job tra
The National AIDS Fund (NAF) received $157,500 to replace a portion of our match funding to successfully implement the 09-10 National AIDS Fund AmeriCorps Program.  This total request of $157,500 has allowed the NAF to provide for member match
This award focuses on a multi-state AmeriCorps Program in which the WestCare Foundation, Inc. has been awarded ARRA funding to support six (6) full-time AmeriCorps Members serving in California, Florida and Kentucky. Members in these three (3)
Right Fork of Hobble Creek - refurbish approximately 7 miles of existing asphalt road surface that is in poor condition and asphalt roads in Balsam and Cherry Campgrounds; hauling and placing appoximately 7 miles of aggregate; and removing and
Forest Service Recovery Act Project Agreement for improvements on Santaquin Canyon, Hobble Creek Canyon and Payson Canyon (including Nebo Loop Road)
RV (Recreational Vehicle) Parks and Campgrounds
Reconstrauction and resurfacing of 1.7 miles of T358, Beaver Meadows Road, formerly called Abraxas Road.
Road Project Agreement-total project estimate $36,318.
increases to employees wages and lastly for cost of living type increases in expenses to rent, utilities, food, mileage reimbursements, repairs and other costs associated with child care centers.
The temporary ARRA COLA funds will offset employee's regular costs for health care. With this award, $600 of the ARRA COLA funds will be distributed to each employee to off-set their costs for health benefits. After distribution of temporary AR
This grant awards a cost-of-living adjustment (COLA) increase of 1.84% in the amount of $214,006 for Head Start and $28,815 for Early Head Start to pay for over 300 staff salaries over the 12-month period folowing the effective date or this gra
Head Start and Early Head Start COLA and Quality Improvement.  COLA of 1.84% through ARRA stimulus bill for salaries, benefits, and operating costs.  Quality Improvement will include hiring Floating Teacher 2's, Improving Community Advocate sal
This award provides support to the Early Head Start program at California Hospital Medical Center.  Namely, a Cost of Living adjustment for staff.  This award also supports quality improvement for Early Head Start program at California Hospital
This award provides for ARRA Head Start Expansion funded to serve 24 children.  The Head Start program promotes school readiness through center & home based preschool programs fro children ages 3-5 from low income families while also providing
The American Recovery and Reinvestment Act (ARRA) funding was made available to expand Head Start services in unserved and underserved areas of San Bernardino County. The overall goal of the program is to increase the school readiness of young
This grant awards funds made available to the Head Start program under the American Recovery and Reinvestment Act (ARRA) to expand Head Start services to 36 additional children.  This action awards $67,683 in start-up costs and $203,049 for pro
Town of Oro Valley -Pavement Preservation, LaCholla, First, Lamber, Moor,Tan
A full understanding of human evolution requires understanding modern human diversification and the origins of modern human populations. As modern humans expanded out of Africa, genetic drift and selection operated to change allele frequencies
ALFRED: Ongoing Growth of an Anthropological Resource
Grant Name:Capital Improvement. Purpose/Goals: Conduct alterations and renovations on the 2nd floor of a facility at 11 Wilbraham Road in Springfield and subsequently create an adolescent clinic providing quality primary healthcare, reproductiv
Dental and Administrative Expansion to expand capacity, improve care delivery and increase operational efficiencies.
JOSEPH M. SMITH COMMUNITY HEALTH CENTER, INC.
The CIP proposal will address community needs for affordable prescription medications and increased demand for medical services through allowing JMSCHC to increase clinical space and set up a 340B satellite pharmacy at our Waltham site and buil
Capital Improvement Project (CIP) Funds were received for two projects:  (1) renovation of Na Pu`uwai office located at Kulana `Oiwi to multi-use examination rooms and (2) electronic health record (EHR) readiness consultation and subsequent sel
Renovation and Electronic Health Record readiness
Several communities continue to struggle for basic health services following the destruction of Hurricane Katrina in 2005. Over this period, the EXCELth Primary Care Network has created primary care access in three  of these communities that wi
ARRA - Capital Improvement Project.  Project I.  Expansion of Harvest Family Health Center. CIP funds have been approved to off-set construction costs to expand Harvest Family Health Center; owned and operated by Carolina Family Health Centers,
Replace the existing outdated x-ray unit with a digital unit including upgrading electrical service to the rad-room at the Baker, WV site  Build out and equip three dental operatories in the new dental office in Petersburg, WV.  Needed expansio
Northeast Missouri Health Council, Inc. (NMHC) will utilize this CIP funding to construct a facility that will provide both the Administrative and Information Technology (IT) infrastructure space necessary to implement a complete electronic hea
The Capital Improvement Project (CIP) monies will be used as a one-time expense for general facilities improvements of Vida Y Salud Health Systems, Inc. This award money will be utilized for the remodeling/renovation and facility improvement of
ARRA-Capital Improvement Program.  This is the final ARRA-Capital Improvement Program report.  With the ARRA Capital Improvement Program funding, PCHS has been able achieve the goal of integrating Electronic Health Records (EHR) and Live Quest
La Clinica del Pueblo was awarded Capital Improvement Project funding to address infrastructural improvements to sustain the overall operations of the facility. With the acquisition of this funding, LCDP plans to address three areas of focus th
Site construction continues to proceed with the projection of substantial completion at the end of the first quarter of 2012, and occupancy and operations beginning in 2nd quarter. During the fourth quarter of 2011, the space was completely enc
A new Health Care Center was constructed in Bristol, Florida.  The Center is 4,000 square feet and will house all clinical services. Prior to this the provider was operating out of two small facilities which presented logistical problems for pa
ARRA - Capital Improvements Program - Liberty County
The American Recovery and Reinvestment Act Capital Improvement Program (CIP) grant supports the construction, repair and renovation of health centers as well as the purchase of new equipment and health information technology.  In particular, th
The Capital Improvement Project (CIP) will enable Covenant House New York's Medical Clinic to enhance their patient management applications with the installation of the EHR System and eClinical Works (ECW).The CIP facilitates the training neces
To fulfill the strategic goals of the Board we seek to migrate our current practice management and electronic health record systems to a certified, integrated system that will be able to manage both primary health and behavioral health practice
ARRA - Capital Improvement Program  The purpose of this award is to update dilapidated equipment and furniture for Open Door Health Services.  Additionally, some new equipment will be purchased to support expansion of services as ODHS moves to
JHCs CIP funding is divided into three projects ? 1) Dental project, 2) Health Center renovations, 3) Health Information Technology project. 1) The dental project is complete and the dental hygienist is utilizing the new operatory with new cons
The HRSA CIP Funding includes two projects: 1) E.H.R. implementation and 2) Equipment, Furnishings and Renovation.
The purpose of this award is to replace outdated equipment in our Center. X Ray machine that has been in use for 32 years will be replaced with a digital radiography. This eliminated the uses of chemical processing of film and reduce space requ
Grant name - ARRA - Capital Improvement Program. Purpose and Goals - The grant provides funding for the replacement of termite and water-damaged siding on the building in addition to new and replacement medical and computing equipment. Project
Grant Name - ARRA-Capital Improvement Project Purpose - To constuct a 7,000 sq ft building to house a medical and dental clinic in Bernie Missouri.  To purchase, install and implement the PACS system for the x-ray department at each medical sit
ARRA - Nursing Workforce Diversity Program is a three-year project with two main goals: 1) Increase number of RNs and BSNs from disadvantaged or underrepresented backgrounds, and 2) Ensure access to culturally appropriate health services for al
ARRA - Nursing Workforce Diversity Program
Indiana Wesleyan University Nurse Faculty Loan Program FY 2009-2010  The purpose of the grant is to address funding needs for students enrolled in the Master of Science in Nursing program in Nursing Education offered by the Department of Gradua
The PhD program in Nurse Science at VUSN prepares graduates to serve as active nurse scientists who can fulfill the academic role of nurse faculty. The VUSN PhD graduates have a rich history of pursing academic careers, with all but one current
The goal of this project is to understand how latent viral infection drives changes in the antiviral CD8 T cell repertoire over time, using murine gammaherpesvirus-68 (?HV68) as a model of latent herpesvirus infections.
CD* T cell responses to gamma-herpesviral infection
Grant Name:  Health Center Controlled Network EHR Implemenatation Grant.  Purpose:  The purpose of the EHR Implementation Grant is to support health center controlled networks such as ARCH to implement electronic health records in member health
ARCH Integrated Electronic Health Record Project
GEORGIA ASSOCIATION FOR PRIMARY HEALTH CARE, INC
Electronic Health Record Implementation for Health Center Controlled Networks ? HRSA -09-198 Georgia HCCN HIT Expansion ? Atlanta Urban FQHC EHR & HIE   H2LIT16823 Oakhurst Medical Centers, Inc., Southside Healthcare, Inc., and West End Medical
AltaMed Health Services Corporation (AltaMed) received $746,250 from HRSA to support EDR Implementation and Integration with our CCHIT-certified EMR across our dental clinic sites and portable dental exam and treatment units in poorly-served ur
ARRA-AltaMed Electronic Dental Record (EDR)
This award was for the creation of a new Health Center with the intent to expand health services to the people of Liberty County and in the cities of Midway and Hinesville.  This grant allowed for Diversity Health Center to keep the doors open
In our NAP grant, Peak Vista proposed a Mobile Family Care Clinic, offering a full continuum of medical and dental services with referrals for behavioral health services.  The Pikes Peak region contains nearly 600,000 residents, with 22.5% livi
Big Sandy Health Care (BSHC) operates Hope Family Medical Center in Magoffin County, Kentucky; Mud Creek Clinic and Physicians for Women Center in Floyd County, Kentucky; Shelby Valley Clinic in Pike County, Kentucky and recently opened the Mar
VERMONT ASSOCATION OF SNOW TRAVELERS INC
American Recovery and Reinvestment Act Award to provide jobs and improve and maintain transportation infrastructure within the Green Mountain National Forest.The funds are being used for maintenance on snowmobile trails which are also utilized
Green Mountain National Forest/VAST Snowmobile Trails Maintenance Program
'Streetscape Construction','Reconstruction and streetscape improvements of 6.5 lane miles of Pennsylvania Avenue'
Great Streets Pennsylvania Ave from 27th St. SE to Southern Avenue
To accomplish restoration of coastal prairie habitat and contribute to re-establishing a self-sustainng population of the federally threatened golden paintbrush plant (Castilleja levisecta).  The project will 1) augment the existing golden pain
Naas Preserve Prairie Habitat Restoration and Golden Paintbrush Recovery
Reintroduce Pink Sand Verbena, a plant species that was previously thought to be extirpated in Washington State.  Establish a second population of Pink Sand Verbena on tribal lands to assist with the recovery of this plant species.  Actions und
new water transmission pipeline to integrate the source into the system.
Blanding Well A Development & Integration Project
This contract funded by the Recovery Act is for the purpose of developing and implementing several site-specific cooperative partnership projects for the enhancement of wildlife habitat.  Projects focus on increasing the resilience of wildlife
Galisteo Watershed Wildlife Corridor and Habitat Restoration Project
Sullivan, Intersection of Route 1 and Ashville Road
Grant Name - Capital Improvement Program Purpose - to Implement Electronic Health Record System. Goals - to improve service delivery and increase patient health outcome through the implementation of electronic health record system. The importan
BIN 3305560, GRIST MILL RD (TR13) BRIDGE OVER STONY CREEK
US-191 @ Black Hills Rd (Back Country Byway) at MP 159.5
ERIE CANALWAY TRAIL IMPROVEMENT PROJECT, CITY OF SCHENECTADY
Bismarck - North 19th Street from 75' N of E Century Ave to Oregon Dr
Mandan - 3rd Ave NE from 5th St NE to 14th St NE
Mandan - 27th St NW from 12th Ave NW to 8th Ave NW
Mandan - Old Red Trail from Sunset Drive to Collins Avenue
MOUNT DESERT ISLAND BIOLOGICAL LABORATORY (INC)
The Mount Desert Island Biological Laboratory, a non-profit biomedical research institution with an expanding year-round research program, seeks support for construction of a 13,267 sq. ft. laboratory building to promote collaborative multidisc
Extramural Research Facilities Construction:  Construction of New Biomedical Research Laboratory Building
ARR Capital Improvement, Program Alteration Renovation, Repair and Equipment
The High Plains ARRA-Capital Improvement Program (CIP) grant awarded on 6/25/09 was for the purpose of constructing a 5,800 square foot adult health care center. The goal for this project is to create a site that is clinically, structurally, an
Funding to support implementation of a certified electronic health records system,  purchase of equipment which includes IT equipment, upgrading of practice management software, funding for enhancing security equipment  and purchase of a handic
The Georgia Department of Community Health, State Office of Rural Health's Georgia Farmworker Health Program focuses on providing primary and preventive health care to the farmworker population.  Services are provided through six clinical sites
NORFOLK COMMUNITY HEALTH CARE CLINIC, INC.
The Medical/Behavioral Health departments of NCHCC has had the opportunity to join with Health Information Technology Implementation for Health Center Controlled Networks which includes 4 health centers in Nebraska and 1 health center in Iowa.
The Capital Improvement Program (CIP) project expanded the capacity to provide primary and preventive health care services to a medically underserved population. Located in Southern Missouri, Reynolds County is a primary medical, mental health,
The San Juan Health Care for the Homeless Program delivers comprehensive and preventive primary health care services to homeless individuals at urban communities throughout the Municipality of San Juan, designated MUA and MUP since 1978. It is
THE HEALTH & HOSPITAL CORP OF MARION COUNTY
Grant-Capital Improvement Program  Purpose-The purpose of the CIP grant at Citizens was for renovation of the Pharmacy and Dental departments and purchase equipment.  Goals of the Project-renovate the Pharmacy, renovate the dental department to
TO SUPPORT HEALTH CENTER TO ADDRESS CAPITAL IMPROVEMENT NEEDS PRIMARILY CONSTRUCTION  COSTS FOR REMODELING, ALTERATIONS AND RENOVATING EXISTING BUILDING USED FOR THE PROGRAM.  EXPECTED OUTCOME IS TO REDUCE AND/OR ELIMINATE EMERGENCY MAINTENANCE
The grant titled ARRA - Capital Improvement Program provides Peoples Community Health Clinic with capital funding for one-time alteration/renovation and equipment purchase.  The renovation includes re-design of the scheduling  areas and adding
The purpose of Mattapan Community Health Center's (MCHC's) CIP proposal is to address our community's immediate needs by renovating our current, overcrowded health center facility, and upgrading IT equipment and clinical/dental equipment.  To r
Mattapan Community Health Center's Capital Improvement Project (MCHC-CIP)
The Capital Improvement Program grant was awarded to Black River Healthcare to construct a second facility at the Manning site. Once completed, adult and pediatric providers will have more exam rooms to accommodate new patients. Achieving the g
The Capital Improvement Program (CIP) Grant allows funding for projects that address construction, alteration/repair/renovation, heath information technology, and equipment needs.  The $1,203,715.00 award will allow the Community Health Associa
The changing demographics of developed nations underscores the need for regenerative medicine approaches to combat the clinical and financial burden of degenerative diseases. The basic understanding of how tissues are normally maintained by the
Analysis of Stem Cell Dynamics and Differentiation By Cellular Barcoding
The purpose of the Nurse Faculty Loan Porgram is to increase the number of qualified nursing faculty by providing loans to students.
$94,259.00 plus 9% cost share all to be given to doctoral students completing degrees.
The goal of this mechanistic-based study is to identify specific cellular macromolecules involved in methamphetamine (MA)/dopamine (DA) induced neurotoxicity which could potentially serve as targets for pharmacological intervention aimed at att
A MECHANISTIC STUDY OF METHAMPHETAMINE NEUROTOXICITY: INVOLVMENT OF HO-1 & MNSO
Dept. of Pharmacology, Physiology, & Toxicology
This fellowship will support the study of the metabolic control of hepatitis B virus (HBV) biosynthesis and more specifically bile acid regulation of HBV both in cell culture and in vivo. The long-term objectives are to understand the in vivo m
Metabolic Control of Hepatitis B Virus HBV Biosynthesis Role of Fxr and Shp
The goal for this project is to address the current lack of knowledge regarding the host innate immune response to C. Burnetii infection. Specifically, we plan to determine the contribution of various alveolar macrophage subsets to both the ini
Fellowship: Innate Immune Response to Coxiella burnetii Infection
Chronic hepatitis C virus (HCV) infection afflicts about 3 million people in the United States and is the leading indication for liver transplantation (CDC, NHANES III). Currently treatments are effective in only about 50% of patients. Improved
A NOVEL CULTUE SYSTEM FOR HEPATITIS C VIRUS
This project will qualitatively examine the experience, meaning and interpretation of BZD dependence in a sample of community dwelling women age 75 or older.  It will also determine whether culture has a role in the experience of BZD dependence
The Experience of benzodiazepine dependence among older women:  A cultural analysis.
UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC.
This grant provides postdoctoral level funding for studies on the mechanism innate immunity to African trypanosomes. Humans exhibit an innate immunity to the mammalian parasite Trypanosoma brucei brucei.  Immunity to T. b. brucei is provided by
Mechanism of membrane permeabilization by a cytolytic high density lipoprotein
Under normal conditions, most T lymphocytes are made in the thymus. However, the thymus degenerates with age, beginning around puberty.  Because output of new Tcells from the thymus is proportional to its mass, age-related thymic atrophy result
Identification of Stromal Responses During Castration Mediated Thymic Regrowth
Aging is associated with a decline in cognitive function that begins in midlife. Age-associated deficits in learning and memory are often accompanied by impaired synaptic and structural plasticity in the hippocampus, including diminished adult
REWARDING EXPERIENCE AND THE AGING BRAIN  Awardee Organization: PRINCETON UNIVERSITY
The 1918-19 influenza virus claimed the lives of more than 20 million people worldwide and the determinants of its extreme virulence are currently under investigation. Influenza A virus harbors a segmented, negative-sense RNA genome contained w
NOVEL ROLE OF 1918 INFLUENZA VIRUS NEURAMINIDASE IN HEMAGGLUTNIN ACTIVATION
Project Summary:  West Nile Virus (WNV) is an NAID Category B infectious agent and since its introduction into the United States in 1999, has become the leading cause of arboviral encephalitis in the United States.  In recent WNV outbreaks, hea
Defining the host antiviral response to West Nile Virus
Bacterial cell cycle progression and development rely on a backbone of transcription factors and phosphorelay systems to temporally coordinate gene expression with events in the cell. The phosphorelays have been relatively well characterized in
Master Regulators of Transcription in the C. Crescentus Cell Cycle
Title:  T cell Survival and Metabolic Fitness in Inflammation and Infection  Purpose:Postdoctoral Fellowship.  This funding mechanism is to (1) support the training of scientists at the postdoctoral level, and (2) to advance scientific knowledg
TAU CELL SURVIVAL AND METABOLIC FITNESS IN INFLAMMATION AND INFECTION
LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY
Genetic analysis of the NKT cell response to Streptococcus pneumoniae:  Invariant (I) natural killer (NK)T cells are a unique T lymphocyte subset that expresses an invariant T cell antigen receptor (TCR) alpha chain that is conserved between mi
Genetic analysis of the NKT cell response to Streptococcus pneumoniae
The induction of peripheral tolerance is critical for deterrence of autoimmunity.  Most self-reactive T cells are deleted during development in the thymus.  However, this additional process is not absolute and occasionally some self-reactive T
ENDOGENOUS T CELL TOLERANCE IN THE INTESTINAL MUCOSA
Provide Meharry Medical College researchers with a modern vertebrate animal facility for research on cancer, women's health, brain and behavior disorders, cardiovascular diseaes, HIV AIDS research and environmental diseases.
Developing and improving the institutional animal care facility
The objective of this project is to enhance current and future research productivity and to remain in compliance with Federal regulations for the care and use of research animals at the Center City campus of Drexel University College of Medicin
Animal Facility Renovations of New College Building
This award is for equipment only.  The University of Rochester Medical Center (URMC) is sponsoring the construction of a new enhanced Animal Biosafety Level 3 (eABSL3) facility in shell space of the URMC MRBX basement. The facility is being des
URMC EQUIPMENT PROCUREMENT FOR AN EABSL3 FACILITY FOR SMALL ANIMAL INVESTIGATIONS
Vital biomedical research and integrity of scientific data depend on excellent animal care. The University of Alabama at Birmingham (UAB) Animal Care and Use Program is committed to the long-term goals of providing and maintaining consistently
DEVELOPING AND IMPROVING INSTITUTIONAL ANIMAL RESOURCES
NEAR NORTH HEALTH SERVICE CORPORATION, THE
--Enhancing Quality Using Information Technology in Patient Care.  Purpose: This is a Health Center Controlled Network electronic health records implementation project.   Goal and Importance of Goal: To utilize the Alliance's integrated service
ARRA Health Information Technology Implementation
CORPORACION DE SERVICIOS DE SALUD Y MEDICINA AVANZADA
During this reporting period we continued promoting the services in the communities and in the clinic to increase new patients. The community interventions to promote COSSMA?s services as the best alternative to primary health care services in
Increase Demand for services for hiring a Physician, Physician Assistant and two medical assistants for the Chewelah Medical Clinic.
SJMCS's IDS project will consist of two specific components:  retained positions at a fixed clinic site, and expanded capacity at one fixed clinic and three mobile sites.  Mercy Clinic North - IDS funding will allow SJMCS to retain three critic
Saint Joseph's Mercy Care Services, Inc.
The ARRA Funding - Increased Services to Health Centers will allow the health center to utilize a multicultural team of outreach workers to increase utilization of medical and dental health services to a medically  underserved population. As we
ARRA - Increased Services to Health Centers
The NJ Department of Agriculture received funds through the American Recovery and Reinvestment Act of 2009 (ARRA) to assist in the purchase of equipment for School Food Authorities (SFAs) participating in the National School Lunch Program (NSLP
NJ Department of Agriculture NSLP Equipment Assistant Grants
It is the primary objective of this program to elucidate correlates of immune-mediated protection against HIV-1 infection using pre-clinical animal models. To this end, Project 1 will determine humoral and cell-mediated immune responses to an a
Correlates of protection against SIV/SHIV challenge
PACIFIC INSTITUTE FOR RESEARCH AND EVALUATION
The revised principal aim of this P20 is to form an Impaired-Driving Center (IDC), to build institutional capacity  to create a laboratory for the investigation of the individual and epidemiological risk and protective factors for impaired driv
This three-year funding proposal for a P20 Center provides a new paradigm for medication development for the treatment of alcoholism by bringing experienced alcohol researchers together with experts in chemistry, proteomics, gene delivery and D
Medication Development for Treatment of Alcoholism
This application, responding to RFA-OD-09-005 Recovery Act Limited Competition: Core Centers for Enhancing Research Capacity in U.S. Academic Institutions, proposes to recruit and support two new Assistant Professor Faculty to the Massachusetts
Faculty recruitment for programs in the biology of age-related cognitive change
Significance  We propose to recruit a bright and productive young clinical investigator from the University of Rochester to a tenure-track Assistant Professorship and mentor her development as a researcher in mind/body medical interventions. He
CAM Approaches to Management of Sleep and Disease Progression in Cancer
Acupuncture, a component of traditional Chinese medicine, has been used for thousands of years to treat a multitude of ailments. Recent scientific evaluation has suggested that this therapy may demonstrate clinical benefit for a number of condi
Core Center for Multimodal Evaluation of Acupuncture Mechanisms
The Center for Nanoscale Materials and Biointegration (CNMB) was formally approved by the University of Alabama Board of Trustees in February 2006 as an interdisciplinary research and student-training center focusing (i) on the synthesis and ch
ENHANCING FACULTY RECRUITMENT IN NANOSCALE SCIENCES FOR BIOMEDICAL RESEARCH
The Department of Pathology at the University of New Mexico proposes a NIGMS Biomedical Research Core Center (BRCC) in Immunology and Imaging that will recruit and mentor two outstanding PhD, MD or MD/PhD tenure track research faculty at the As
NIGMS Biomedical Research Core Center in Immunology and Imaging
The intracellular movement of molecules is a fundamental property of living cells, being reflected in a very large number of cellular processes, including cell division, transport within nerve axons and endocytosis of nutrients and signaling mo
CELL BIOLOGY HIRES IN TRAFFICKING AND OPTICAL IMAGING AT THE UNIV. OF MINNESOTA
The department of Molecular Genetics and Cell Biology is applying to the NIGMS for a Recovery Act grant (RFA-OD-09-005) to recruit a tenure track Assistant Professor in the area of Biochemistry of Chromatin Structure and Function. The departmen
BIOCHEMISTRY OF CHROMATIN STRUCTURE AND FUNCTION - ARRA
The innate immune system is an evolutionarily ancient and highly conserved first line of host defense against pathogens in plants, fungi, insects and mammals. Innate immunity is essential for early responses to infection and effective immune re
Recruitment of New Faculty in Innate Immunity Research
This NHLBI PSO application requests funding for two years salary plus appropriate start up funds for a newly independent investigator whose research will complement the research underway in the Brigham & Women's Hospital's (BWH) Division of Sle
The overall purpose of this P30 award was to recruit an outstanding new physician scientist faculty member and foster the development of this individual in the University of Minnesota Pulmonary, Allergy, Critical Care, and Sleep (PACCS) Divisio
Supporting New Faculty Recruitment Through BioMedical Research Core Center
UNIVERSITY OF PUERTO RICO-MEDICAL SCIENCES CAMPUS
New Recruitment to Expand Neuroscience Research at the UPR School of Medicine: The purpose of this application is to request funds to support the hiring of two new faculty at the Department of Anatomy & Neurobiology (A & N) of the University of
NEW RECRUITMENT TO EXPAND NEUROSCIENCE RESEARCH AT THE UPR SCHOOL OF MEDICINE
The Department of Physiology and Neurobiology (PNB) at the University of Connecticut has a long history of high research productivity. The objective of this proposal is to recruit a new tenure-track assistant professor to a position that was pr
Recruitment of Neurobiology Faculty at the University of Connecticut
Faculty Recruitment in Novel Therapeutic Strategies for Neurodegenerative Disease. This proposal seeks support for new faculty recruitment to enhance research capacity at Emory University in the area of novel therapeutic strategies for neurodeg
FACULTY RECRUITMENT IN NOVEL THERAPEUTIC STRATEGIES FOR
The Jungers Center for Neurosciences Research proposes to recruit a newly-independent neuroscientist to expand and enhance its research efforts around the theme of Axonal Degeneration and Regeneration. Founded in 2006, the Jungers Center is a n
Jungers Center New Faculty Recruitment in Genetic Models of Axonal Degeneration
DESCRIPTION: This proposal is directed to solving the problem of the slow rate of generation of high resolution structures of integral membrane proteins that can be useful as drug targets and in medicine. The group combines established expertis
Improving Rate/Quality Limitations in Membrane Protein Structure Determination
The present application takes advantage of the high quality data that already exist and proposes a study that can be completed within 2 years (at a cost of $737,367). It will combine data from the youngest PYS cohort from ages 7 through 25 with
Persistance and Desistence in Heavy Drinking and Violence
This application is focused on the design, synthesis and evaluation of potential biological probes and treatment agents for alcohol dependence based on their actions on the nociceptin (NOP) receptor. We seek to identify compounds thai act as pa
Discovery and Development of Nociceptin Receptor Ligands in Alcohol Dependence
The overall goal of this project is to evaluate the effects of binge-type alcohol exposure on oocyte quality. There are no studies known to us that have examined the effects of binge alcohol consumption on fertility in women or any animal model
Age-related cognitive decline (ARCD) exists in a continuum with more severe cognitive dysfunction that that often is a demeinta prodrome and can be operationally defined as Mild Cognitive Impairment (MCI), and ultimately with dementia.  ARCD is
White matter damage in age-related cognitive decline
Apathy in Alzheimer's dementia (AD) is a significant public health problem with serious adverse consequences for patients and caregivers. Apathy affects approximately 70% of AD patients, making it one of the most common neuropsychiatric symptom
Apathy in Alzheimer's Disease Methyphenidate Trial
Chemotaxis allows polymorphonuclear neutrophils (PMN) to rapidly reach infected sites and inflamed host tissues. Inflammation results in damage of host tissues by excessively activated PMN. Better knowledge of how PMN chemotaxis is controlled m
AUTOCRINE CONTROL OF NEUTROPHIL CHEMOTAXIS
Epstein-Barr virus (EBV) is an extremely successful pathogen, able to persist lifelong as a latent infection within B lymphocytes with little overt disease. However, a breakdown in immune surveillance, e.g., as a consequence of AIDS, remains a
MECHANISMS OF GENE REGULATION BY EBV EBNA-1 PROTEIN
S. enterica serovar Typhimurium is an important human pathogen causing acute gastroenteritis following ingestion of contaminated food. One of the major vehicles of infection for humans is contaminated poultry because the bacteria easily infect
Fimbrial Expression in Salmonella: Regulation and Coordination
Malaria is a major cause of global morbidity and mortality, with its greatest impact on African children who account for most of the 1 to 2.7 million annual deaths (WHO, 2000). P falciparum, the major causative agent of human malaria, has remai
Genome Surveillance for Drug Resistant Malaria
Mosquitoes utilize a variety of strategies to combat pathogens, including viruses. The long term_ goal of the PIs research is to elucidate, at the molecular level, the immune responses of the mosquito vector Aedes aegypti to infection with a ra
Malaria kills over one million people each year. Most malaria deaths occur in Africa and most of the victims are children under five. An effective, affordable vaccine would greatly reduce the morbidity, mortality, and economic burden imposed by
ORAL IMMUNIZATION AGAINST MALARIA WITH RECOMBINANT ADENOVIRUSES
Tuberculosis is endemic among patients with AIDS and follows an aggressive course with poor localization of mycobacteria into granuloma and widespread infection. Granulomas are monocyte rich collections of cells which derive from the circulatin
Evidence suggests that one mechanism of peripheral immunologic tolerance occurs through the process of T cell anergy. Anergic T cells have been characterized to have a defect in TCR/CD28-mediated Ras activation. Recent data have indicated that
Highly specialized professional antigen presenting cells are distributed throughout the skin and include epidermal Langerhans cells (LCs) and dermal dendritic cells (DCs). Our laboratory established some unique properties of cutaneous DCs. We
DISSECTING THE ORIGIN AND THE FUNCTION OF THE CUTANEOUS DENDRITIC CELL NETWORK
Infections with antibiotic resistant bacteria are increasing at an alarming rate. Antibiotic resistance is a particular problem in patients with blood stream infections or sepsis, due to the a mortality that rises exponentially as effective tre
Development of a Molecular Blood Culture
Induction of allograft tolerance would avoid the need for chronic immunosuppressive therapy with its attendant toxicities. We have recently performed a pilot trial of combined non-myeloabiative bone marrow and kidney transplantation (CKBMT) fro
Mechanisms of tolerance in recipients of combined kidney and bone marrow transplantation
Fibrocartilaginous tissues are found throughout the musculoskeletal system in regions experiencing substantial levels of both tension and compression during functional loading. These tissues have highly organized, heterogeneous structures that
MODULATION OF MSC DIFFERENTIATION FOR FIBROCARTILAGETISSUE ENGINEERING
ACL is the most commonly injured knee ligament in sports-related activities, especially in pivoting sports. ACL injury mechanisms, including factors contributing to the 2-9 times higher incident rate in female athletes than their male counterpa
ACL Injury Mechanisms and OffAxis Neuromuscular Diagnosis and Training
Musculoskeletal conditions are exceptionally common and costly to treat. In a 2002 survey of US adults 26% reported back pain and 14% reported neck pain in the previous three months. Expenditures to treat spine conditions alone accounted for at
CAM, MEDICAL SERVICE UTILIZATION AND QUALITY OF CARE
The prevalence of cancer in the United States is associated with costs greater than $100 billion annually, and the causes of this disease are not entirely understood. It remains possible that exposure to chemical carcinogens contributes signifi
MODULATION OF AHR-DEPENDENT SIGNALING BY PPARB/D
The lack of efficient gene delivery systems is the most important barrier to the use of gene therapy for cancer. There is an urgent need to develop vectors that are capable of selective, efficient, and safe delivery of genes to tumors. Until th
MULTI-SEROTYPE ADENOVIRUS VECTOR SYSTEM FOR TARGETED GENE DELIVERY TO TUMORS
weight trimming procedures for a general class of population statistics under a variety of sample designs; develop selection models that accommodate non-ignorable missingness mechanisms in the context of complex survey designs; and develop met
Hierarchical Bayesian Analysis of Complex Sample Survey Data
RNA aptamers have been generated against a variety of proteins including a few cell surface receptors. In general such aptamer act as potent inhibitors of their target proteins both in vitro and in vivo. Moreover, a few of these antagonistic ap
RNA APTAMERS AS CELL SURFACE RECEPTOR AGONISTS & siRNA DELIVERY AGENTS
It is the over 3,800 chemical components of tobacco smoke, which makes it the leading cause of death in America. Associated with cardiovascular disease, chronic obstructive pulmonary disease, and pancreatic disease, tobacco smoke is responsible
Biomarkers of toxic response to low nicotine cigarette smoke
Two hundred million people world wide are affected by thyroid proliferative diseases (TPD), which include goiter, cancer and adenoma. Women are three times more susceptible than men and overall the incidence of thyroid dysfunction occurring in
Intervention models for thyroid proliferative disease using a bioactive food compound
PTEN Deficiency and Tumor Development PTEN is one of the most frequently mutated genes in human cancer. We have previously demonstrated that PTEN plays an essential role in the maintenance of genomic stability and that PTEN controls genome inte
Summary description of the project that matches the Award: Our data indicate that the human prostate-derived Ets transcription factor (PDEF) plays an essential role in tumor suppression via downregulation of the expression of antiapoptotic prot
PDEF and survivin: Prostate cancer prognosis for personalized medicine
The purpose of this project is to develop enabling computational tools for IGART and to show the potential clinical impact of the new paradigm of IGART. The underlying hypothesis of this work is that IGART will greatly reduce the uncertainty in
Computational Tools for Adaptive Radiation Therapy
Purpose: Identify virus and host factors important in polyomavirus SV40 infections and cancer development.  Abstract: Human cancer viruses establish persistent infections in their hosts.  We hypothesize that the risk of viral induced cancer is
Hamster Model of SV40 Infection and Disease
Based on our recent findings, we hypothesize that chromatin coregulators such as ANCCA is a key mediator of specific AR function in the conversion of prostate cancer to the hormone-refractory state. To test our hypothesis, we propose to establi
University of California Davis Medical Center
The goal of this project is to define the mechanisms by which crosstalk between the insulin-like growth factor 1 receptor (IGF1R) and vascular endothelial growth factor (VEGF) receptor pushes oral squamous cell carcinoma (OSCC) cells to metasta
Receptor Crosstalk in HNSCC Metastatic Progression
The overarching goal of this project is to understand two important aspects of epigenetic control during medulloblastoma formation, namely the difference between cancer stem cells and bulk tumor, and the role of DNA methylation dependent gene s
Molecularly targeted agents against receptor tyrosine kinases (RTK), particularly the antiangiogenic agents (AAs), have caused a paradigm shift in cancer chemotherapy. These agents target tumor angiogenic mechanisms (sprouting of new blood vess
SINGLE AGENTS WITH DESIGNED COMBINATION CHEMOTHERAPY POTENTIAL
Aim 1. We will define the structural and biological basis for the shedding of mRANKL by MT1-MMP. - Aim 1.1. Investigate the structural basis of MT1-MMP shedding of mRANKL; - Aim 1.2. Identify MT1-MMP/mRANKL complexes at the surface of pc cells.
THE MT1-MMP/RANKL/RANK AXIS IN PROSTATE CANCER BONE METASTIA
Multiple myeloma (MM) is still incurable B-cell malignancy affecting more than 14,000 Americans annually. Myeloma tumor cells can survive even the most aggressive treatment available today, leading to disease relapses. The long-term goal of thi
TARGETING SURFACE B2M FOR MYELOMA AND BONE THERAPY
Our current treatment algorithms provide for treating all patients with advanced colorectal cancer (and in the future, possibly those with stages II and III) with combined chemotherapy and bevacizumab. While the therapeutic benefit has been mar
Interaction of anti-angiogenic and cytotoxic therapies in colorectal cancer
Transposase activity was thought to be extinct in humans because DNA movement can be deleterious in higher organisms, resulting in genomic instability and perhaps malignancy. However, we isolated a human transposase protein termed Metnase that
Immediate treatment of CIN 2,3 has been the standard of care, even though some such lesions likely would never progress to ICC and, in young women, some lesions spontaneously regress. However, because there is no way to predict the natural hist
Epigenetic changes predict disease course of HPV-related lesions in women 16-24
There is mounting evidence that lymphatic angiogenesis plays an important role in tumor metastasis. While we know a little bit about the VEGF family members that stimulate lymphangiogensis, there is still much we don't know. This application pr
Childhood aggressivity at age 7 is associated with a fourfold increased risk for illicit drug dependence at age 25. Despite high rates of aggressivity in children with histories of parental neglect, theory-driven and efficacious drug prevention
EARLY PREVENTION OF SUBSTANCE USE INITIATION IN FOSTER CARE
This R01 grant proposal describes a randomized, double-blind, placebo-controlled trial of nicotine nasal spray (NNS) as an aid for smoking cessation in 70 individuals with schizophrenia.  The objectives of this study are to determine the effica
Double-Blind, Placebo-Controlled Trial of nicotine Nasal Spray as an Aid for Smoking Cessation in Schizophrenia
According to national epidemiologic surveillance systems (i.e., Monitoring the Future, the National Survey on Drug Use and Health), adolescent nonmedical use of highly addictive prescription opioid analgesic drugs (e.g., Vicodin®, Oxycontin®)
Internet as Supplier: Preventing Adolescent Use of Non-Medical Addictive Rx
NATIONAL DEVELOPMENT AND RESEARCH INSTITUTES, INC.
Substance use among youth remains a major public health problem. About half of all 12th graders have tried an illicit drug and over 72% of this same age group have used alcohol. Rates of abuse of prescription opioids among youth are estimated t
Computer-Delivered Psychosocial Treatment for Adolescent Substance Use Disorders
Prescription opioid misuse and abuse are increasing problems in the United States. In the 2006 National Survey on Drug Use and Health, 5.2 million Americans had illicitly used a prescription opioid in the past month. National rates of illicit p
Neuropharmacology of Tramadol: Clinical Efficacy and Abuse Potential
The broad, long-term objective of the proposed randomized clinical trial is to evaluate the efficacy and mechanisms of change of two cognitive-behavioral aftercare treatments for alcohol and other drug (AOD) use disorders in preventing AOD rela
Mindfulness Based Relapse Prevention: Efficacy and Mechanisms
As reported in each ARRA update:  The Revised ARRA Aims include Aim 1 of the original application (to compare extinction of limbic activation by  seen vs. unseen cocaine cues), and the Exploratory Aim (to examine DA-modulating genetics).    Aim
EXTINCTION OF LIMBIC ACTIVATION TO %22UNSEEN%22 COCAINE CUES
In vivo profiling of glial and neuronal activities in psychostimulant abuse (PI: Christina H Liu, PhD) Drug addiction is a chronic brain disorder that severely hampers productivity of many members of our society. One of the most used drugs of a
In vivo Profiling of Glial and Neuronal Activities in Psychostimulant Abuse
Methamphetamine (METH) use is of major public health concern given its prevalence among individuals who are HIV infected and its association with HIV transmission risk behaviors, particularly high-risk sexual behavior.  METH use strongly alters
COMT GENOTYPE AND RISKY DECISION MAKING IN HIV AND METHAMPHETAMINE DEPENDENCE
This project will use fMRI to study the cognitive and brain mechanisms of risk avoidance. Impairments in these mechanisms are associated with substance use and abuse. Knowledge of such mechanisms can inform the prevention and treatment of subst
Neural Mechanisms of Risky Behavior Avoidance
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER OF SAN ANTONIO
This R01, submitted in response to RFA-DA-09-001 (Medications Development for Cannabis-Related Disorders), has been modified to accommodate a 2-year budget. The grant proposes using pre-clinical measures of cannabinoid withdrawal in non-human p
PHARMACOTHERAPY OF CANNABINOID WITHDRAWAL: PRE-CLINICAL STUDIES
Obesity and health complications related to obesity, including diabetes, impact a significant proportion of the population in the United States, and projections indicate that the number of obese and overweight individuals will continue to rise
'Three-Dimensional Imaging of Whole Cells By Using X-Ray Diffraction Microscopy' X-ray protein crystallography is currently the primary methodology used for determining the 3D structure of protein molecules at near-atomic or atomic resolution.
THREE-DIMENSIONAL IMAGING OF WHOLE CELLS BY USING X-RAY DIFFRACTION MICROSCOPY
The M2 protein of influenza A virus forms a pH-gated proton channel that is   important for viral infection and replication. The antiviral drug amantadine used to be effective in blocking this channel, until the recent emergence of a mutant, S3
Solid-State NMR of influenza M2 protein in lipid bilayers
RNA interference (RNAi) is a widespread gene-silencing phenomenon initiated by a double-stranded RNA that is converted into small interfering RNAs (siRNAs).  Although the detailed mechanism whereby siRNA silences its target gene expression is n
Familial episodic ataxia (EA) syndromes are rare and heterogeneous (EA1-EA7 to date) monogenic disorders, the study of which has illuminated previously unrecognized but important roles of ion channels and transporters in neuronal and cerebellar
The long-term goal of the proposed research is to reveal the physiological functions and in vivo mechanisms of G protein-coupled receptor (GPCR) endocytosis and postendocytic trafficking.  GPCRs are the largest family of membrane receptors that
Rhodopsin endocytic trafficking and Drosophila visual sensitivity
Many men with prostate cancer will be affected by side effects of hormonal therapy. The impact of hormonal therapy for prostate cancer on cognitive function, a major determinant of quality of life, remains unclear. This study proposes to use br
Imaging the effects of androgen deprivation therapy on cognitive functions in patients with non metastatic prostate cancer
Title: Significance of Pituitary Leptin to Gonadotropes    Pituitary leptin changes in a cyclic manner that indicates it may facilitate or permit the secretion of gonadotropins. There are parallel reductions in pituitary leptin and LH during fo
Significance of Pituitary Leptin to Gonadotropes
Cloning and Characterization of Zebrafish Endocrine Pancreas Genes Abstract:  The long-term goal of this application is to develop strategies for cell based replacement therapy to treat diabetes by understanding the molecular mechanisms regulat
CLONING AND CHARACTERIZATION OF ZEBRAFISH ENDOCRINE PANCREAS MUTANTS
Stress is a well known risk factor for relapse in alcohol-dependence. The goal of this project is to identify specific stress-related genes that may predict the risk for relapse in alcohol dependent subjects and allow individuals at higher-risk
Stress-Related Changes in Gene Expression as Biomarkers of Relapse Vulnerability
The goal of this research proposal is to identify virulence factors in Francisella tularensis Schu S4. In nature, F. tularensis causes the zoonotic disease tularemia. F. tularensis is a category A select agent because of its highly infectious n
Identification of Francisella tularensis extracellular proteins expressed in vivo
Many Gram-negative pathogenic bacteria employ a complex protein secretion apparatus termed type III secretion system (T3SS) to transport bacterial effector proteins into eukaryotic host cytoplasm. The effector proteins delivered by T3SS are cap
A recent report by Kohanski et al. demonstrated that multiple classes of bactericidal antibiotics stimulate the production of hydroxyl radicals thus accelerating bacterial cell death in Escherichia coli.  Although different classes of antibioti
Antibiotic pressure and selection of TCA cycle mutants in Staphylococcus epidermidis
Memory CD8 T cells are a critical component of adaptive immunity that protect us against infectious disease and even cancer, however the mechanisms for how these cells develop during infection or vaccination are not clear. The ultimate goal of
Determining How Adjuvants Alter Effector and Memory T Cells During Vaccination
The human ?-herpesviruses, Epstein-Barr virus (EBV) and Kaposi?s sarcoma-associated herpesvirus (KSHV), establish persistent infections that are maintained for the life of the host and are associated with the development of a variety of maligna
Can persistent gamma-herpesvirus be purged from the host?
Defining the neural pathways and circuits of the brain is critical for understanding neurological and psychiatric disease. The proposed experiments will characterize how brain reward circuits respond to changes in levels of a hormone that is pr
Development of Neuronal Tracers to Study Leptin Modulation of Dopanmine Circuits
Personnel are in place and research is progressing to develop nanoplatforms for selectively killing a bacterium that resides in a biofilm consortium. The long term goal is to test the hypothesis that selective elimination of periodontal pathoge
Targeted Combinatorial Therapy for Treatment of Periodontal Disease
The specific aims of this project are (1) To create a working partnership among interdisciplinary stakeholders (land developers, home builders, realtors, home buyers, policy makers, and public health professionals) aimed at deepening current un
Age-related macular degeneration (AMD) is characterized since its earliest stages by formation of deposits between the Bruch's membrane (BM) and the retinal pigment epithelium (RPE), termed drusen. In recent years, a role for inflammation in th
Auto-Antibodies as Serum Biomarkers for Age-Related Macular Degeneration
CARDIOVASCULAR AND THERAPEUTIC POTENTIAL OF REPROGRAMMED HUMAN FIBROBLASTS   Differentiation of the cells of the inner cell mass into the specialized cells required for forming the complex tissues that comprise living organisms has traditionall
CARDIOVASCULAR AND THERAPEUTIC POTENTIAL OF REPROGRAMMED HUMAN FIBROBLASTS
is for funding to determine whether structural and functional changes in the brain white matter pathways that connect frontal and temporal cortices are significantly different in people who are at genetic high risk for developing schizophrenia
Sleep is an essential biological function that has physiological, behavioral and temporal characteristics. It is regulated by homeostatic and circadian processes. The knowledge of the importance of sleep and the adverse effects of sleep depriva
Feasibility of measuring sleep in a critical care environment
Obstructive sleep apnea (OSA) afflicts 20 million adults in the United States, and is associated with increased morbidity and mortality. Major male-female differences in the incidence and co-morbidites of the disorder are poorly understood. Sin
GENDER DIFFERENCES IN NEURAL DEFICITS ASSOCIATED WITH OBSTRUCTIVE SLEEP APNEA
Pain caused by activation of pain-sensing peripheral neurons (nociceptors) is a major source of human suffering and economic loss. Pain sensation requires the coordinated participation of a variety of ion channels. Our long-term goal is the dev
Novel Analgestics from Australian Funnel-Web Spider Venom
The function of most genes in our genome remains a mystery. In order to determine their function, we must use model systems such as frogs specifically Xenopus. In this proposal, we will create new technologies to determine gene function in Xeno
Developing transposon methods for insertional mutagenesis in Xenopus
Collaborative R34 grant which is 1/3 CBT(Cognitive Behavioral Therapy) for Anxiety Disorders in Autism: Adapting Treatment for Adolescents. This project involves adapting a promising intervention for elementary school children with Autism Spect
1/3 CBT FOR ANXIETY DISORDERS IN AUTISM: ADAPTING TREATMENT FOR ADOLESCENTS
Opportunistic infections are the primary cause of suffering and death in individuals with AIDS. Many of these infections are produced by parasites that rarely affect individuals who are not immunocompromised. Unfortunately, successful combinati
Exploring Novel Targeting Strategies for AIDS Protozoal Pathogens
'Diet and Exercise (DE) Program for Alzheimer Prevention'   This project directly addresses three challenge areas: first broad Challenge Area (01) Behavior, Behavioral Change, and Prevention (specific topic 01-AG-102 Neural mechanisms), second
DIET AND EXERCISE (DE) PROGRAM FOR ALZHEIMER PREVENTION
This application addresses the broad Challenge Area (08) Genomics, Beyond GWAS 08-DK-102. The overall genetic architecture and pathogenic mechanisms of complex disorders such as Crohn's disease (CD) is incompletely defined at present. Genome-wi
Beyond single point GWAS: Genetics of Crohns disease in Ashkenazi Jews
Despite best intentions in practice and recent innovations, the sciences continue to experience high attrition rates, particularly in students’ first and second years of college and specifically among underrepresented racial minority students
INTRODUCTORY STEM COURSES: SORTING, HARVESTING, OR NURTURING STUDENT TALENT
A new non-invasive technology to diagnose preterm labor :  Premature delivery accounts for 12% of all births in the United States and is identified as the leading cause of perinatal morbidity and mortality. Despite advancements in medicine and
A new non-invasive technology to diagnose preterm labor
Neuroimmune Factors Mediate the Co-morbid Expression of Enhanced Fear, Alcohol Consumption and Depression in an Animal Model of Post-Traumatic Stress Disorder;  This award addresses broad Challenge Area 01-AA-102 Functional Roles of Neuroimmune
NEUROIMMUNE FACTORS AND CO-MORBID FEAR, DEPRESSION AND ALCOHOL CONSUMPTION
This application addresses broad Challenge Area (01) Behavior, Behavioral Change, and Prevention and specific Challenge Topic 01-OD (OBSSR)-101* Tools for studying cultural phenomena. Population dynamic models of culture conceptualize culture a
RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE
This application addresses broad Challenge Area (01) Behavior, Behavioral Change, and Prevention and specific Challenge Topic, 01-GM-104: Mechanisms of Behavior Change Research. Cognitive-behavioral therapy (CBT) is well-established as an effec
ARRA: Identifying Multiple Mechanisms of Change in Alcoholism Treatment
Of two vaccine candidates tested in rats at the Scripps-based Koob lab one was found to be superior and advanced to the rat self administration studies. This vaccine evoked anti-cocaine titers of about 106 and in a parallel study using locomoto
(RCI)-an existing public-private, multidisciplinary collaboration of health plans, provider groups, public health authorities, and other key stakeholders.  RCI was established to address poor performance in clinical outcomes of chronic conditi
COMPARATIVE EFFECTIVENESS AND OUTCOMES IMPROVEMENT (CEOI) CENTER
The goal of this project is to test risk and resiliency pathways linking social determinants of health and child characteristics to young children's health. We will examine the role of four social determinants of health (i.e., social position,
The Study of Multiple Social Determinants of Young Children's Health
The Scholarships for Disadvantaged Students program provides scholarships to full-time, financially needy students from disadvantaged backgrounds enrolled in health professions and nursing programs.
ARRA- Scholarship for disadvantaged students
This award is to fund Scholarships Disadvantaged Allopathic Medical and Nursing Students as per the 2009 Poverty guidelines
The purpose of Boston Unviersity's Scholarship for Disadvantaged Students (SDS) Program is to increase diversity in the health professions by awarding scholarships to financially needy students from disadvantaged backgrounds with financial need
Through education research and public service the University of Tennessee Health Science Center is committed to the highest standard of achievement in all programs regardless of a student's cultural background.  With this commitment in mind, th
To coordinate local, State, and Federal resources contributing to primary care service delivery and workforce issues in the State to meet the needs of medically-underserved populations through health centers and other community-based providers
Rural Development issued an amended Letter of Conditions on February  10, 2011 to reduce the loan and grant amounts. This reduction was warranted based on a decrease in project costs resulting from a reduction in construction costs. The amended
Town of Wausau  Water Line Upgrade and Extension
etension tubes, and five power supplies.
Mobile Data Terminals for Police Vehicles
ABCD, ASIAN BUSINESS COMMUNITY DEVELOPMENT
Highway improvements on Route 15 in Dover-Foxcroft
Planning & Design Services for Rehab Predator Exclusion Cover at Lower Raceways at Carson NFH
Electric Power Generation (EPG)-Part of Project R8CA install photovoltaic (PV) systems. AE design for PV systems.
This project is to repair the raceway headbox and walkway  Deck at the Quilcene National Fish Hatchery (NFH). The concrete headbox structure, which serves nine 8' x 80'raceways, is severely deteriorated.  Metal channels that provide support to
SR-101L @ Beardsley Rd/Union Hills Dr in GLENDALE
The purpose of the House of Wellness Renovation was to improve patient care and confidentiality.  The pharmacy has expanded and increased the number of prescriptions that it curently issues.  The pharmacy has outgrown its present location.  The
Renovation of Ho-Chunk Nation House of Wellness
East Valley Highway - S. 212th Street to SR 167
ARRA Cost of Living Adjustment (COLA)and Quality Improvement Funding consistent with the provisions of Section 640(a)
Implementation of American Recovery & Reinvestment Act
This awards provides for Head Start 2009 ARRA COLA Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start and Early Head Start program.  Head Start promotes the school readiness
Classical Pavlovian conditioning has a major role in the development and persistence of drug addiction. Consistent with this view, exposure of drug-abstained subjects to drug-associated cues precipitates relapse which is a major problem in the
RECONSOLIDATION AND EXTINCTION MECHANISMS FOR THE TREATMENTOF DRUG ADDICTION
RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA
One of NIDA's highest priorities for funding is the development of effective pharmacotherapies for substance related disorders.  In response to RFA-DA-09-005, soliciting pilot clinical/human studies of interventions that specifically target mec
Medications Development for the Treatment of Cannabis Related Disorders
The major goals of this project are to establish a method for optical analysis of neural circuits. Neuroplasticity is central to fundamental processes in the brain, including learning, recovery after brain injury, and neural circuit changes res
Optogenetic Tools for in vivo Analysis of Cortical Circuit Plasticity
The purpose of this award is to further our understanding of the genetic basis of Age Related Hearing Impairment (ARHI).  Our current understanding of the genes that underlie this form of hearing loss is limited to a handful of candidate genes
Genetic Analysis of Age Related Hearing Impairment
The broad, long-term objective of this study is to identify molecular targets regulating replacment tooth formation (RTF) in zebrafish that can be manipulated to treat tooth agenesis in humans.  Zebrafish are the only currently available, tract
ALK8 REGULATION OF REPLACEMENT TOOTH FORMATION
The reduction in dental caries over the past 30+ years has been remarkable and started largely with the introduction of fluoride to the water supply. Increased access to dental care, improved oral hygiene, fluoride incorporation into profession
Dentin Fluoride as a Biomarker for Childhood Fluoride Intake
The spread or metastasis of tumor cells to the lymph nodes of patients with oral cancer is the leading cause of treatment failure and death in this disease. An accurate and reliable clinical test to detect lymph metastasis in oral cancer patien
MOLECULAR ANALYSIS OF OSCC TUMOR INVASION
Tuberous sclerosis complex (TSC) is caused by germline inactivating mutations in the TSC1 or TSC2 genes, which encode hamartin (TSC1) and tuberin (TSC2), respectively. Both humans and mice with mutations in TSC1 or TSC2 can develop cystic kidne
Roles of Tuberin (TSC 2), Hamartin (TSC1), and Rheb in Renal Cyst Pathogenesis
The Hepatoprotective Role of the Orphan Nuclear Receptor LXR  The liver X receptors (LXRs) are transcriptional factors highly expressed in the liver. The goal of this study is to determine whether LXRs play a hepatoprotective role in preventing
The Hepatoprotective Role of the Orphan Nuclear Receptor LXR
The Ras-stimulated Raf-MEK-ERK kinase cascade is used over and over again to control many aspects of animal development, including tube formation. How this common signaling cascade elicits specific responses is still poorly understood. ERK is t
While considerable progress has been achieved in understanding basic mechanisms of glomerular and renal fibrosis, the absence of a true experimental model for human FSGS has made it difficult to clearly understand how these basic mechanisms ap
Non-alcoholic steatohepatitis (NASH) is one of the most common causes of liver disease in the United States, and accounts for the majority of cryptogenic cirrhosis. NASH is associated with the 'metabolic syndrome', which includes insulin-resist
Molecular and Genetic Analysis of Murine Steatohepatitis
Human chronic cholestatic liver diseases (i.e., cholangiopathies) trigger the proliferation and damage of cholangiocytes that are the epithelial cells that line the biliary apparatus. These cholangiopathies cause morbidity and mortality and are
Role of the Renin-Angiotensin System in the Regulation of Biliary Proliferation
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON
DESCRIPTION (provided by applicant): Over 400,000 Americans have end-stage renal disease (ESRD) requiring dialysis or kidney transplant for survival. ESRD in the US population doubled in the last decade and this increase is driven by diabetes a
To study the function of the nuclear receptor LRH-1. The orphan receptor LRH-1/NR5A2 is thought to be a key regulator of the complex process of bile acid biosynthesis and potentially other important metabolic pathways in the liver, but there is
Pancreatic involvement is common and the injury progresses to pancreatic insufficiency (PI) in the majority of patients with cystic fibrosis (CF). Currently, there are no treatments to halt the progression of pancreatic disease in CF and the ex
Characterization of Pancreatic Disease in a Novel Porcine Cystic Fibrosis Model
Collectively, these studies will validate the proposed novel concepts towards high strength biomimetic scaffolds. Optimization of the mechanical properties of the newly developed scaffolds will be part of a future application submission.
Multifunctional Block Copolymer Scaffolds for Bone Repair
This project will study whether certain pesticides interact with genetic factors in causing Parkinson's disease (PD). PD is a common disease of the nervous system that affects  people later in life, causing movement disorders including tremors
Pathological interactions of a-syn, mitochondria, and pesticides in PD models
Emerging technologies for manufacture and use of nanoparticles (NP) are numerous and the exponential increase in their use drives the need for understanding toxicology of these particles. Most non-carbon NP contain one or more toxicologically-a
Role of Physico-chemical Properties in the Reprotoxicity of Inhaled Cd NP.
Primary Open-Angle Glaucoma (POAG), the leading cause of blindness in the United States, is characterized by a progressive loss of retinal ganglion cells (RGCs). Elevated intraocular pressure (IOP) is a major risk factor for RGC loss in glaucom
Proteases in IOP-mediated glaucomatous damage
The expression of specific cytochrome P450s (CYPs) in vascular smooth muscle cells and endothelial cells (EC) and the critical contribution of their products to vascular function suggest important roles for these genes in vascular homeostasis.
ARRA CYP1B1 and Retinopathy of Prematurity
The long term objective of this proposal is to gain insights into the neuron generation potential of the mammalian retinal-ciliary margin as well as the molecular and cellular properties of cells within. This has important implications for the
NEUROGENESIS AT THE MAMMALIAN RETINAL-CILIARY MARGIN
LONG-TERM OBJECTIVE: To gain insight into the cellular and dynamic mechanisms and functional roles of neural feedback loops for visual processing. SPECIFIC AIMS: The aim is to provide an understanding of the dynamic and neural mechanisms of fee
NEURAL FEEDBACK MECHANISMS FOR VISUAL PROCESSING
Visual deprivation is one of the most extreme conditions leading brain regions to adopt new functions in response to environmental constraints, that is, to compensate for the loss of a sensory modality. Studies in visually deprived animals and
SENSORY CORTICAL ORGANIZATION AND CROSS-MODAL PLASTICITY IN BLIND SUBJECTS
The purpose of this grant is  to understand how Notch signaling suppresses the differentiaiton of lens fiber cells.  Our recent studies indicate that the Notch signaling pathway inhibits lens fiber cell differentiation.  We found that Herp2, a
When one chooses to look at something, one makes a saccadic eye movement to it. Because saccades are so brief, they cannot be guided by visual feedback, but must rely on feedback after each saccade to check the accuracy of that movement and, if
Is Saccade Adaptation Guided By Reinforcement?
The overall purpose of the project is to examine how kinesin motors interact with microtubules. This work will contribute to our understanding how healthy and cancer cells divide. The findings may suggest new approaches for developing novel che
UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL
ARRA - Mechanistic Studies of DNA Repair and Damage Response  The overall goal of this proposal is to elucidate the structural and dynamic properties of MutSa-DNA  complexes that signal initiation of DNA mismatch repair (MMR) versus initiation
ARRA - Mechanistic Studies of DNA Repair and Damage Response
Biological Properties of HIV-1 V3 Evolutionary Variants (ARRA) This ARRA funded grant is a supplement to the parent grant R37-AI44667 !Biological Properties of HIV-1 V3 Evolutionary Variants!.  This funding is accomplishing two important goals
Biological Properties of HIV-1 V3 Evolutionary Variants (ARRA)
The recycling endosome (RE) is a nexus for membrane transport in both polarized and nonpolarized cells. In polarized cells, endocytic traffic originating on both the apical and basolateral surfaces passes through the recycling endosome. Basolat
Functional Subdomain Organization of the Recycling Endosome
This proposal will delineate the structural features of a group o f Eph receptors (EphB2, EphA2, and EphA4) in their apo forms as well as in complex with their cognate ligands and peptides. These receptors are members of the largest receptor ty
Structural Determinants of Promiscuity and Selectivity in Ephrin-Eph Binding
Currently, there are no specific high-affinity inhibitors or activators of mitochondrial ATP-dependent proteases. The identification of such compounds will allow us to determine the role that these proteases play in mitochondrial dysfunction, w
High throughput screens for modulators of mitochondrial ATP-dependent proteolysis
Mastery of written and oral communication skills is essential for the survival of faculty everywhere. It can be a challenge for scientists from any background, but may be especially difficult for those who are educationally under-prepared or wh
IMPROVING RETENTION OF MINORITY TRAINEES: MENTORING IN SCIENTIFIC COMMUNICATIONS
Germ cells are specialized cells that undergo mitotic proliferation followed by meiosis and cellular differentiation to generate haploid gametes for sexual reproduction.    Errors in human germ cells are quite common and result in a high freque
Analysis of checkpoint function in the germ line
Human- and hominoid-specific genes are among the most interesting genes in the human genome. These genes are likely to have evolved by duplication of segments of DNA ( a process called segmental duplication) that occurred during primate expansi
TBC1D3: A HOMINOID-SPECIFIC GENE THAT REGULATES GROWTH FACTOR RECEPTOR SIGNALING
Inhibition of androgen synthesis is the current treatment of human diseases like prostate cancer and polycystic ovary syndrome. This approach is suboptimal. By defining how the enzyme responsible synthesizes these androgens, we hope to establis
Activation of Androgen Biosynthesis and Drug Metabolism by Cytochrome b5 - ARRA Stimulus 2 Yr Resub
Recent advances in the field of structural biology and quantitative proteomics mean that there is now sufficient information available to allow the construction of meaningful, working molecular models of physiological environments. Such environ
Molecular Simulations of Folding & Association in Physiological Environments
All living things need sulfur, and cysteine desulfurases are necessary to provide sulfur in the proper form.  These enzymes are found primarily in mitochondria in all human cells. Here we aim to characterize for the first time the active mitoch
We have shown that circulating levels of vascular endothelial growth factor (VEGF) and placental growth factor (PlGF) are elevated in mouse and human models of sepsis, that VEGF plays a pathogenic role in sepsis, and that the upregulation of Pl
ROLE OF VEGF AND PLGF SIGNALING IN SEPSIS
'The roles of the V-ATPase at the molecular and physiological level will be investigated. The V0 sector subunit “a” has been shown to play important roles in diverse membrane fusion or secretion functions independent of the V-ATPase proton-
Molecular Studies of the Roles and Regulations of the v-ATPase V0 Sector
Spermatogenesis is a complex process where the proliferation/differentiation of germ cells is intimately tied to their apoptosis. How these germ cell corpses are cleared and how this engulfment process links to normal spermatogenesis, are poorl
Sertoli Cell Mediated Engulfment of Apoptotic Germ Cells
The maturation of mathematical reasoning skills is a hallmark of human cognitive and academic development. Cognitive, developmental and educational psychologists have provided valuable insights into the complex and dynamic developmental changes
COGNITIVE NEUROSCIENCE OF MATHEMATICAL DEVELOPMENT
The goal of this supplement will be to support our studies on the intercellular bridge. Intercellular communication is essential for all multicellular organisms. A unique form of intercellular communication occurs between germ cells; 0.5-3 mm â
DEFINING THE MAMMALIAN INTERCELLULAR BRIDGE INTERACTOME
Neonatal jaundice occurs in 60?70% of all newborn infants. It is caused not only by an overproduction of bilirubin, but also by a transient failure to excrete this metabolite. Hyperbilirubinemia is exacerbated by hemolytic diseases, such as Rhe
Chromium Mesoporphyrin in the Prevention of Neonatal Jaundice
In the developing vertebrate central nervous system, radial glial cells play critical roles in supporting brain architecture and, more recently discovered, possess self-renewing capabilities as well as gliogenic and neurogenic potential. Radial
The Role of Eg5 in Radial Glial Development in the Zebrafish Spinal Cord
The broad, long-term objective of this application is to extend our current tool for identifying regions of imminent skin break-down in amputee prothesis users into a more clinically useful tool for prosthetic fitting and modification. In addit
MEASURING IN-SOCKET RESIDUAL LIMB VOLUME FLUCTUATION
This award, 'Sources of Change and Stability in Low Income Black Marriages,' is funding a longitudinal and observational study of black and white newlywed couples recruited from low-income communities.  Couples are interviewed in their home, re
SOURCES OF CHANGE AND STABILITY IN LOW-INCOME BLACK MARRIAGES
The prevalence of autism  spectrum disorders  (ASD)  is now estimated  to be 1  in 150, making  it a major burden  to society.  It has been clearly determined  that genes play a major  role  in  the  etiology  of  autism,  but  previous  geneti
A SYSTEMS BIOLOGY APPROACH TO UNRAVEL THEUNDERLYING FUNCTIONAL MODULES OF ASD
The overall goal of this project is to elucidate how anti- and pro-atherogenic factors modulate nuclear factor (NF)-:B activation to influence vascular inflammation and atherogenesis. A major hypothesis is that extracellular signal-regulated ki
Mitogen-activated Protein Kinases and NF-kB Activation in Vascular Smooth Muscle
The long-term goal of this research is to determine the physiological and pathological roles of the different MLCK isoforms, encoded by the mylk1 gene, in the vasculature. The mylk1 gene encodes a 220kDa myosin light chain kinase (MLCK), a 130k
Function of the 130kDa MLCK in vasculature physiology and pathophysiology
Pulmonary embolism (PE) affects many, with an estimated incidence of up to 69 cases per 100,000 persons annually. In the U.S., 101,000 patients were hospitalized with a primary diagnosis of PE in 2002, resulting in direct medical costs of $720
Outpatient Treatment of Low-Risk Patients with Pulmonary Embolism
Congenital cardiac malformation is the most frequent birth defect and it contributes to advanced heart failure in the pediatric and adult population. An enhanced understanding of the transcriptional networks that direct cardiac progenitors duri
Transcriptional Regulation of Cardiac Morphogenesis
The long term goal of this continuing work is to quantitatively characterize skeletal muscle structure and function noninvasively with nondestructive imaging modalities, and to implement robust methods for diagnosing disease and improving clini
MONITORING DISEASE AND THERAPY IN DYSTROPHIN-DEFICIENT MUSCLE USING ULTRASOUND
Five million patients suffer from heart failure in the United States. Clinical trials of stem cell therapy, initiated because of the severity of this problem, have yielded modest results. Understanding the epigenetic programs that induce differ
MECHANISMS FOR STEM CELL DIFFERENTIATION INTO CARDIAC MYOCYTES
Dahl salt-sensitive rats (SS) exhibit defects in the regulation of their renin-angiotensin system (RAS) that result in chronically low plasma renin activity (PRA) and low circulating ANG II levels, even when they are normotensive and fed a norm
Role of ANG II in Maintaining Vascular Relaxation in Dahl S Rats
Interventions that may stimulate or regulate healthy cardiac vessel growth are of considerable clinical relevance. Research conducted primarily on tumor growth and organ development has identified two major cellular mechanisms of angiogenesis:
Thyroid Hormone Regulation of Vasculature in Adult Myocardium
DESCRIPTION (provided by applicant): Soluble growth factors play a vital role in virtually all tissue development and regeneration processes, and inductive growth factors are critical components of many emerging tissue engineering strategies. H
ARRA Biomaterials for local regulation of growth factor signaling
Extracellular nucleotides (ATP, ADP and UTP) are known to activate type-2 purinergic (P2Y and P2X) receptors on platelets, endothelium and immune cells to induce vascular inflammation and thrombosis. Cellular ectonucleotidases hydrolyze P2-medi
For the past 20 years, we have studied the genetic underpinnings of hormonal factors leading to hypertension (HTN) in the HyperPATH cohort. From these studies, we have identified several associations between single nucleotide polymorphic (SNP)
Aldosterone, Histone Demethylase and Cardiovascular Disease
High serum levels of low density lipoprotein (LDL) are associated with atherosclerosis, the leading cause of death in the USA. The long term goal of this proposal is to develop new treatments that lower LDL levels and alleviate cardiovascular d
Global and regional epigenetic changes, including CpG dinucleotide methylation and de-methylation, in response to environmental cues, have been implicated in a growing number of human diseases including various cancers, rheumatic and autoimmune
Transcriptional and Epigenetic Regulation of P66shc: Relevance to Endothelial Fun
Atherosclerosis is a chronic disease characterized by lipid infiltration and inflammatory cell recruitment in the vessel wall that can lead to serious clinical consequences such as myocardial infarction and stroke. While of the role of monocyte
Diabetes is associated with serious cardiovascular complications that include heart failure. Data from studies conducted in animal models and human subjects suggest that alterations in fatty acid metabolism, independent of atherosclerosis, are
LIPID BIOMARKERS FOR DIABETIC COMPLICATIONS
Ion channels use the energy stored in ionic gradients to initiate rapid signaling events essential for the function of virtually every cell in the body. Although channel activation can occur in response to a variety of different stimuli, once o
Regulation of PMCA Pump-Channels by Oxidant Stress
Investigators in many biomedical research areas?from post-marketing surveillance of adverse drug events to biomarker studies of gene-expression data to outcomes analyses of healthcare interventions?have a common need to extract clinically or bi
Open-Source Toolkit for Knowledge-Based Querying of Time-Oriented Data
The long-term goal of our research is to develop resources and tools for knowledge retrieval management in the biomedical domain. As the pace of biomedical research accelerates, researchers become more and more dependent on computers to manage
ONTO-BIOTHESAURUS: ONTOLOGICAL REPRESENTATION OF GENE/PROTEIN NAMES FOR BIOMEDICA
The objective of this proposal, which is designed to address the ever increasing need for integrated knowledge discovery in biology and medicine, is to enable the discovery, verification, and validation of hypotheses concerning interrelationshi
(ARRA) OAMiner: Integrative knowledge anchored hypothesis discovery
As stated in the abstract, the overall goal of the proposed research is to determine if pregnant teenagers’ life stress and stress related changes in blood pressure (BP), as well as other biological indices of stress (cytokines, HPA–axis ac
Biobehavioral Assessment of Stress in Adolescent Pregnancy: Parinatal Outcomes
Schizophrenia is a major mental disorder that strikes in young adulthood and that has a heritability of 80-90%. Even with state-of-the-art treatment, schizophrenia often produces life-long disability, creating a pressing need to delineate the h
Genetic Determinants of Brain Structure and Disease Risk in Schizophrenia
Schizophrenia & Other Psychotic Disorders
The understanding of how nervous system activity gives rise to behavior and cognition is being revolutionized by experimentation with molecularly-tractable model species such as zebrafish. These efforts are greatly hampered by the lack of autom
AUTOMATED ANALYSIS OF LEARNING AND MEMORY FOR NEURO-DEVELOPMENTAL STUDIES
Neuroendocrine or immune events occurring within the perinatal environment often produce effects on brain and behavior that endure throughout an organism's life span. An estimated 1/3 of pregnancies suffer complications involving infection or t
EARLY LIFE INFECTION, NEUROINFLAMMATION, & MEMORY
Statement of Purpose (15 words): To identify which genes harbor individual or collections of rare DNA variants predisposing autism. Abstract: We propose a partnership between expert large-scale sequencing centers and a collaborative network of
Elucidating the Genetic Architecture of Autism by Deep Genomic Sequencing
DESCRIPTION (provided by applicant): To enhance participant recruitment efforts for genetics studies and other large- scale etiological research efforts, there is a need for an instrument that can be practically and efficiently employed in rese
1/2 DEVELOPMENT OF A SCREENING INTERVIEW FOR RESEARCH STUDIES OF ASD
Convention suggests that the blood brain barrier (BBB) prevents certain drugs and neurotoxins from gaining access to dopamine (DA) neurons in patients with Parkinson’s disease (PD) unless a specific transport mechanism exists.  However, we sh
Blood Brain Barrier Dysfunction in Parkinson's Disease
CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE/CWRU
The overall aim of this project is to clarify the relationship between neuronal activity in the internal segment of the globus pallidus (GPi) and the development, phenotypic distribution and severity of dystonic movements in patients with prima
Inflammation can augment dramatically the sensitivity of nociceptive sensory neurons. In some cases, the actions of inflammatory mediators are fairly well understood; however, there are signaling pathways for which we have very little knowledge
Sphingosine 1-Phosphate Receptors and Sensitization of Sensory Neurons
In the dopaminergic neurons, free dopamine in the cytosol is a unique source of endogenous toxins leading to neuron death; however, dopamine of physiological concentration is not sufficient to cause cell death. Dopamine may become toxic when ot
Mechanisms of Selective Neurodegeneration in Parkinson Diesease
Stroke continues to be the leading cause of long-term disability among adults and its prevalence will continue to rise as the population ages. Developing analytical strategies for improving quality of life and independence following stroke are
PERCEPTION AND RECOVERY OF MOTION FOR VISUALLY GUIDED BEHAVIOR IN HUMANS
Numerous studies have shown that the protein tyrosine phosphatase SHP-1 modulates the expression of proinflammatory genes in leukocytes and glia that have been shown to cause inflammatory demyelination in the CNS. Accordingly, genetic deficienc
ARRA: Deficiency of SHP-1 Expression and Function in Multiple Sclerosis
Molecular Genetics of Midline Glial Development Glia perform a variety of important roles in controlling and supporting neurotransmission in the nervous system. The Drosophila midline glia play a unique role in CNS development by controlling th
Molecular Genetics of Midline Glial Development
'High-speed, wide field fluorescent imaging of cortex in freely moving animals  This project will produce a miniature microscope/imaging system which can be head mounted and will allow the recording of optical signals of changes in membrane vol
High-speed, wide field fluorescent imaging of cortex in freely moving animals
This project will improve scientists' ability to use medical imaging to quantitatively assess the effects of healthy  development, aging and disease on the connectivity between different regions of the human brain. Scientific  interest in brain
Tract-Specific Analysis of Brain White Matter
Adrenoleukodystrophy (ALD) is a rare and oftentimes fatal progressive neurodegenerative disease. The most common form of the disease is X-linked (X-ALD); it occurs equally in all ethnic groups with an estimated incidence of 1:17,000. X-ALD is a
MODELING NEURODEGENERATION AND ADRENOLEUKODYSTROPHY IN DROSOPHILA
SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH
Neural stem cells (NSCs) can be propagated in vitro for extensive periods of time while retaining the ability todifferentiate into neurons, astrocytes and oligodendrocytes. However, NSCs are limited in their potential toyield specific neuron ty
DEFINING FATE POTENTIAL IN HUMAN ESC DERIVED NEURAL STEM CELLS
Hyperglycemia in diabetes leads to kidney damage that may ultimately culminate in end stage renal disease (ESRD), the most severe stage of chronic kidney disease. ESRD patients must rely on frequent hemodialysis treatments to extend life. Some
Endothelial Progenitor Cells in Diabetes and Renal Failure
This grant provides RO3 level funding to develop mitochondrial transfection of African trypanosomes. Humans exhibit an innate immunity to the mammalian parasite Trypanosoma brucei brucei. Trypanosoma brucei is the causative agent of African hum
Development of a Transfection System for Trypanosome Mitochondria
HENRY M JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY M
A major impediment to successful treatment of Staphylococcus aureus is its tendency to develop antibiotic resistance. Methicillin-resistant Staphylococcus aureus (MRSA) has become a household word in the U.S., with recent outbreaks occurring am
Structure and Cell-Wall Targeting of the Staphylolytic Enzyme Lysostaphin
Our ability to explain and control the adhesion of Listeria monocytogenes to surfaces is limited by the lack of molecular-scale studies on how the surface biopolymers of L. monocytogenes affect their attachment to surfaces. My long-term goal is
MOLECULAR MECHANISMS OF L. MONOCYTOGENES ADHESION THROUGH SURFACE BIOPOLYMERS
Giardia is an important cause of diarrheal disease in humans and other animals. Safer and more effective therapies are needed. We propose in this research to evaluate several candidate compounds (in addition to SP 1020 - our lead compound). To
Anti-Giradia Cyst Wall Synthase Drugs: In-vivo Testing
Our ultimate goal is to develop a general protocol that will define bacterial adhesion receptor:ligand interactions, in their native states as a function of fluid shear - for both pure and mixed culture biofilms. With NIH support, we will devel
EFFECTS OF SHEAR ON SPECIFIC ADHESION RECEPTOR EXPRESSION AND BINDING IN THE BACT
Invasive aspergillosis (IA) is an important cause of respiratory and disseminated infection in immunocompromised patients, and the most common cause of infectious pneumonic mortality in recipients of hematopoietic stem cell transplants. Mortali
MANIPULATION OF HOST ANGIOGENESIS AS A THERAPEUTIC STRATEGY AGAINST INVASIVE PULM
Deterioration of cartilage in adults due to trauma or disease is a major health issue in industrialized nations. Because cartilage lacks a regenerative ability, the therapeutic approach of creating cartilage implants in vitro has recently been
Transglutaminase 2 in cartilage formation
Degenerative disc disease and its associated chronic lower back pain is a major U.S. health problem with estimated costs of up to $50 billion yearly. Despite decades of research, a fundamental, multidisciplinary mechanistic understanding of dis
Stem Cells from the intervertebral disc: do they vary in degeneration?
Dermal fibrosis is a hallmark of systemic sclerosis. We have previously demonstrated that stimulation of adenosine A2A receptor promotes collagen production in vitro while blockade of the adenosine A2A receptor attenuates development of dermal
Purinergic Modulation of Dermal Fibrosis
H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC.
With the growing cohort of cancer survivors now numbering 11 million Americans, appropriate follow-up care is pivotal to their ongoing long-term health. Despite guidelines regarding surveillance for recurrence and monitoring of toxicities and l
Evaluating Survivorship Care Planning in Colorectal Cancer
Diet-induced obesity, insulin (INS) resistance, and type 2 diabetes have reached epidemic proportion among women in the United States, and each of these health problems significantly increase a woman's risk of developing breast cancer. Studies
ERR-GAMMA-DEPENDENT MAMMARY TUMORIGENESIS IN RESPONSE TO BPA AND A HIGH-FAT DIET
In recent years new psychoactive plants and their active secondary metabolites have been emerging on the streets. An example is the strong hallucinogenic mint Salvia divinorum and its active metabolite salvinorin A. This use of new hallucinogen
Chemistry and Pharmacology of Newly Emerging Psychoactive Plants
These studies are designed to explore the feasibility of designing new opioid analgesics that we predict will produce less analgesic tolerance and limited side effects such as constipation and respiratory suppression. The experiments will be ba
Agonist-Directed MOR Desensitization in Opioid Analgesic Tolerance
This application responds to RFA-DA-09-016, 'Behavioral Pharmacology and Genetics: Translating and Targeting Individual Differences,' and describes studies that will determine the genetic basis for individual differences in the effects of amphe
GENETICS OF INDIVIDUAL DIFFERENCES IN AMPHETAMINE EFFECTS ON STARTLE GATING
Cochlear implant technology has developed consistently and rapidly, since auditory prostheses first came into widespread use about twenty years ago. Nowadays, cochlear implant devices can guarantee that even profoundly deaf people can enjoy hea
BLIND PROCESSING FOR BETTER SPEECH RECOGNITION WITH COCHLEAR IMPLANT DEVICES
There is accumulating evidence for an increasing incidence of chronic diseases in the human population. These diseases are generally complex, with aspects of genetic control interacting with environmental stressors to trigger the symptoms of th
A Novel Murine Model of Chronic Inflammatory Periodontitus
Tissue engineering involves time- and sequence-dependent procedures where the final outcome is unknown until the restored tissue is formed and functioning. Monitoring changes in the biomechanical properties during tissue development, maturation
Regenerative Elastography: Monitoring Soft Tissue Reconstruction
Proton magnetic resonance spectroscopic imaging (MRSI) allows the in vivo determination regional distribution of various neurochemicals. The pathologic specificity and inherently quantitative information provided by MRSI should help understand
INTEGRATED AUTOMATED SOFTWARE TOOLS FOR FAST ANALYSIS OF MAGNETIC RESONANCE SPECT
DESCRIPTION (provided by applicant): Patient motion is a major issue in nuclear medicine imaging studies, which require substantial time to acquire enough counts to produce clinical-quality images. Motion correction algorithms exist but have li
PATIENT MOTION SENSING IN NUCLEAR MEDICINE SCANS
The pre-placodal ectoderm (PPE) gives rise to the sensory organs in the vertebrate head, which frequently are subject to congenital defects and damage. In animal models, it has been demonstrated that the expression of the transcription factor S
Novel Six1 co-factors and their role in placode development
Birth Defects, Genetic Disorders & Developmental Disorders
In accordance with this goal, and because of the limitations and risks associated with antibiotic prophylaxis for GBS infection, we have undertaken the development of a maternal GBS vaccine. We propose to encapsulate a GBS surface protein, C5a
Development of a Univalent Vaccine Against Group B Streptococci Infection
The health and nutrition of young children is of importance not only for the immediate improvement in their well-being but also because of the longer-term impacts on children's physical and cognitive development. It is believed that improvement
The Effects of Early Childhood Health Interventions on Human Capital Development
This project will explore how historic changes in young women?s access to oral contraception affected the health of women and their children. During the 1960s and 1970s, most states changed the age at which young unmarried women could obtain a
The Impact of Early Access to Oral Contraception on the Health of Women and Child
Adolescents who are maltreated are at elevated risk for developing internalizing problems and externalizing problems. However, not all maltreated adolescents are equally vulnerable to developing mental health problems. Understanding factors tha
ARRA Funded:  Developmental Patterns of Internalizing and Externalizing Problems in Young Adolescents
Intrauterine growth restricted newborns have an increased risk of adult obesity, hypertension and coronary heart disease. Obesity alone accounts for 65-78% of essential hypertension. Although the mechanisms underlying these associations are not
Adipocyte Renin-Angiotensin System and Progaramming of Hypertension
Upregulation of the renin-angiotensin system and increased vasoconstrictive response to angiotensin II (AngII) are observed during hypertension in pregnancy (HTN-Preg) and preeclampsia. Although the renin- angiotensin system is upregulated duri
Vascular Angiotensin Type-2 Receptor in Normal and Hypertensive Pregnancy
The objective of this study is to determine the relationship between the severity of emphysema in COPD patients and abnormality in the expression of key mediators of retinoid action in the lungs
Abnormality in gene expression of key mediators of vitamin A action in COPD
Chronic obstructive pulmonary disease (COPD) has been increasing for the past years. Today COPD is the most common cause of death in the US and is classified amongst the top five killers. Other lung diseases such as atopic asthma have been stea
ROLE OF INTERLEUKIN-17 AND INKT CELLS IN COPD
Idiopathic pulmonary fibrosis (IPF) is a chronic lung disorder resulting in progressive respiratory insufficiency and lung fibrosis with fatal outcome. The pathogenesis of IPF remains unclear. Focal-adhesion-kinase-related non-kinase (FRNK) is
FOCAL ADHESION KINASE AND FAK-RELATED NON-KINASE IN IDIOPATHIC PULMONARY FIBROSIS
Novel therapeutic targets for the treatment of chronic obstructive pulmonary disease (COPD) are urgently needed, as the incidence of COPD - a chronic inflammatory lung disease that imposes tremendous economic burden on the health care system -
Interleukin-17 mediated inflammation in COPD
Heart & Circulatory System Diseases & Disorders Research
This is a 2-year grant application in response to PA-06-391: Research on Autism and Autism Spectrum Disorders R03. Clinical, animal, and genetic evidence points to a role for the hormone oxytocin in autism and suggests that oxytocin related abn
AUTISTIC ENDOPHENOTYPES AND THEIR ASSOCIATIONS TO OXYTOCIN AND CHOLESTEROL
The treatment of infectious diseases caused by antibiotic resistant microorganisms requires a better understanding of how antibiotics kill susceptible cells and how resistance develops. The structural features of antimicrobial agents and their
Features of bacterial ribosomal subunit assembly intermediates
The overall goal of this proposal is to gain a better understanding of the developmental processes involved in muscle development, while providing a dynamic learning environment for undergraduate students. In this proposal, we plan to identify
UTILIZATION OF A MOTILITY MUTANT TO ELUCIDATE MYOTOME FORMATION IN ZEBRAFISH
Glucose uptake is mediated by a family of glucose transporters known as GLUT. Insights into how the activity of these transporters is regulated is important for a better understanding of metabolic disorders such as diabetes and metabolic syndro
The Mechanism for the Acute Activation of GLUT1
This Academic Research Enhancement Award (AREA) grant titled 'Role of the abg Locus of E. coli in Folate Catabolism' was funded July 17, 2009. The overall goal is to involve health professional students in research of the genes and proteins of
Role of the abg Locus of E coli in Folate Catabolism
DESCRIPTION (provided by applicant): The inferior olivary nucleus (ION) is one of the principle inputs into cerebellar Purkinje cells and is involved in regulating movement and gaze. Defects in ION formation have been documented in association
IDENTIFICATION OF FACTORS INFLUENCING CLIMBING FIBER NEURON FATE IN THE DORSAL HINDBRAIN
Channelopathies, genetic disorders in brain and muscle ion channels, are useful to investigate the structural determinants of channel neuronal and skeletal muscle sodium channels to determine the mechanisms for channel functions not well unders
Channelopathy Based Investigation of Domain-Specific Functions in Sodium Channels
During sexual differentiation, an animal's body and brain develop toward a male or female pattern. According to a model established in rodents, this process is hypothesized to occur because of differential exposure to gonadal secretions. For ex
Neurocalcin Regulation of Dimorphic Brain Development
Chlamydia trachomatis, the most common bacterial sexually transmitted disease (STD) agent worldwide, often establishes asymptomatic genital infections which result in serious reproductive complications. In culture, environmental stressors can i
Development of an in vivo model of chlamydial persistence
DESCRIPTION (provided by applicant): Many systemic autoimmune diseases are more common in females than in males. This is particularly evident in Sjvgren's Syndrome, systemic lupus erythromatosis (SLE) and thyroid autoimmunity, where the ratio o
THE RELATIVE ROLED OF SEX AND GENES DURING DEVELOPMENT OF SYSTEMIC AUTOIMMUNITY
Alcohol consumption is generally thought to enhance liver fibrosis. Alcohol-induced liver fibrosis promotes formation of cirrhosis, which increases a risk of liver cancer. Cancer cells have a consistent cytological feature of nucleolar hypertro
Mechanism of Alcohol-Induced RNA Pol Ill-Dependent Transcription
Fetal Alcohol Spectrum Disorder describes a wide range of behaviors and deficits that can occur as a consequence of prenatal alcohol exposure. These effects can range from relatively subtle learning deficits to significant mental retardation. V
In vitro and In vivo models for ethanol withdrawal and antepartum hypoxia
It has been shown that peripheral clearance of amyloid beta peptides reduces amyloid beta peptide levels in the brain through what has been termed a 'sink effect'. We have exploited this 'sink effect' by showing that the peptidase neprilysin, w
Neprilysin and Peripheral Clearance of Amyloid Peptides
Insomnia and sleep apnea (abnormal breathing patterns during sleep) are common in older adults and may each lead to increased risk of disease or death. Insomnia and sleep apnea may exist together in older adults in about 30% of cases and this c
INSOMNIA AND SLEEP DISORDERED BREATHING IN SENIORS: A LONGITUDINAL OUTCOME STUDY
The capacity of lipid molecules in cell membranes to separate into multiple liquid phases, forming so- called lipid rafts, has in the past decade been identified as an important physiological process. Lipid rafts are a control element in the ce
Biomimetic Lipid-hydrogel Systems for Studying Nanoscale Structure Formation in Cell Membranes
to accept the N7 and 2'-O methyl groups from the methyl donor, S-Adenosyl-Methionine (SAM), during the two sequential methylations. We will test the hypothesis by determining why and how the flavivirus MTases catalyze the sequential reactions.
The gut mucosa represents a major entry point for many pathogens and is the target of a variety of inflammatory conditions, including the idiopathic inflammatory bowel diseases (IBD) ulcerative colitis and Crohn’s disease. Emerging evidence s
Role of the Thymus Leukemia Antigen in Mucosal Immunity
Intravenous delivery of recombinant adenovirus (Ad) vectors for gene therapy is hampered by safety and efficacy problems. We have recently discovered a new pathway that is involved in unspecific sequestration and clearance of commonly used Ad5
This project is designed to further our knowledge of the use of molecular hydrogen by the enteric pathogen Salmonella typhimurium.  Molecular hydrogen is produced within the host animal, and some pathogens such as Salmonella capitalize on its a
Use of Molecular Hydrogen by Salmonella typhimurium
Francisella tularensis is a highly efficient zoonotic pathogen that is able to establish a virulent infection with 10 organisms or less. To accomplish this feat the bacterium must have devised efficient means of infecting its host, and effectiv
Virulence Factors of Francisella tularensis
DESCRIPTION (provided by applicant): In this collaborative program, we will develop an integrated Influenza Detection Microchip capable of performing identification of sequence-specific influenza subtypes. Our device accepts clinical specimens
MICROFLUIDIC PLATFORM FOR RAPID INFLUENZA SUBTYPING
Substantial interest in harnessing the immune system as a means of therapy for cancer has arisen from both animal and human subject studies. These studies have revealed the potential benefits of triggering specific immune components, including
NEUROENDOCRINE MODULATION OF T CELL IMMUNITY TO CANCER
This project will develop and apply methods to analyze functioning of a microbicide product vaginal epithelial coating layer - to inhibit transport of HIV virions from semen to tissue and enable microbicide molecules to disable virus. We will c
METHODS TO DETERMINE HIV TRANSPORT & INACTIVATION BY MICROBICIDE COATING LAYERS
The body's defense system can be divided into two components, the innate and adaptive immune systems. The innate immune system acts as the first line of defense against invading pathogens (e.g., bacteria) and is found in plants and all animals.
Beta-Defensins:  Mediators of Gastrointestinal Inflammation
TRANSLATIONAL GENOMICS RESEARCH INSTITITUE, THE
This project is designed to develop and validate novel direct detection real-time PCR assays for the caustive agenst of Valley Fever Coccidiodes posadassi and C.immitis.  Valley Fever, a fungal disease, is one of the most common respiratory inf
Genomic-based diagnostics for Coccidioides the causative agent of Valley fever
DESCRIPTION (provided by applicant): Abstract: Facultative intracellular Brucella species cause brucellosis in animals and humans and have been classified as NIAID category B priority pathogens. Brucella infects the body via the respiratory tra
Development and Evaluation of a Dual-Antigen Nasal Brucella Vaccine
FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH, THE
Septic shock and septic multiple organ dysfunction/injury (MOD/I) are serious clinical syndromes that claim thousands of lives each year in the U.S.  This research project is aimed at identifying new mechanisms and elucidating new molecular pat
Sp1 As a Novel Protective Mechanism Against Septic Inflammation and Organ Injury
Diseases of the Blood & Blood-Forming Organs Research
The long term objective of this proposal is to address the role of IFN??signaling in the regulation of CD4 T cell responses during Mtb infection. Using a well-established mouse model of tuberculosis we will test the hypothesis that IFN??acts di
REGULATION OF CD4 T CELL RESPONSES BY IFN GAMMA DURING TUBERCULOSIS INFECTION
Candida albicans is the most frequently isolated fungal pathogen of humans. This fungus can switch between three distinct morphological forms: yeast, hyphae, and pseudohyphae. The reversible transition between the unicellular (yeast) and filame
In Vivo Induction of Candida Albicans Morphogenesis
Vibrio species are predominantly aquatic bacteria. While many of them are nonpathogenic, some vibrios are associated with severe disease in humans. Vibrio cholerae, in particular, has a long history of causing epidemic and pandemic cholera. Cho
Interaction between Vibrio cholerae and Dictylostelium discoideum
The Alphaviruses are enveloped, plus strand RNA viruses within the Togaviridae family, and are important human and animal pathogens. These viruses invade the host cells through the receptor-mediated endocytosis pathway. The acidic environment i
Structural Studies of Alphavirus Membrane Fusion in Situ
Toxoplasma gondii is a pathogenic protozoan parasite infecting a wide range of vertebrate hosts including humans. In immunocompetent individuals, infection is largely asymptomatic and is controlled by the host's immune response. However, T. gon
A novel vacuolar compartment in Toxoplasma gondii
A. phagocytophilum and NF-kB signaling. This project will investigate how Anaplasma phagocytophilum influences proinflammatory cellular mechanisms by impacting NF-kB activation. The specific pre-nuclear mechanisms targeted in the generation of
Hepatitis C virus (HCV) chronically infects 2-3% of the global population, predisposing the patients to chronic liver diseases and liver cancer. The most effective treatment for HCV infection employs a combination of pegylated interferon-alpha
): For most infections, the immune system confers long-term and sometimes life-long protection against many microbial pathogens. One encounter with a microbial pathogen is sufficient to allow the immune system to remember this pathogen for deca
INNATE IMMUNE SENSING OF MICROBIAL VIABILITY
Mycobacterium tuberculosis latently persist in 2 billion people, representing a major reservoir of tuberculosis (TB) due to reactivation, yet the state of latent bacilli remains a mystery. In order to eradicate TB, we need to understand latency
NANOSTRUCTURED IN VITRO TB LATENCY MODEL
According to the CDC, healthcare-associated infections affect about two million patients in American hospitals each year. Infections like influenza and MRSA routinely spread to and among hospitalized patients, often via healthcare workers. To b
Contact Network Epidemiology of Influenza and Other Nosocomial Infections
Microfluidics for malaria pathogenesis in AfricaSignificance: Malaria parasites infect about a billion individuals and cause up to 2 million deaths per year.  A more complete understanding of the pathology caused by Plasmodium falciparum is nee
MICROFLUIDICS FOR MALARIA PATHOGENESIS IN AFRICA
In the Americas, bats represent a major reservoir for rabies virus (RV) and most of the human rabies cases that were reported during the last twenty years in the US were caused by RV variants that circulate in bat species. Unlike the classical
One major obstacle for HIV vaccine development is the enormous genetic variability in strains between and within individuals. Several studies have proposed a universal HIV-1 vaccine that exclusively targets the highly conserved regions of the v
ANALYSIS OF MUTATIONAL LETHALITY IN HIGHLY CONSERVED AMINO ACIDS OF THE HIV-1 GAG
The HIV-1 virion infectivity factor (Vif) is an essential regulatory protein required for HIV-1 replication in natural target cells such as CD4+ T-cells and macrophages. Recent studies from our group and others have demonstrated that Vif is a c
In the present investigation we will use competitive peptide inhibitiors in an attempt to disrupt the association between ITK and SLP 76 and inhibit the activation of ITK in live cells. This presumably should create a condition that would mimic
All Other Outpatient Care Centers - increase access to primary health care services.
ARRA - Increase Services to Health Centers - Liberty County
vs. retained or restored.  IDS funding will allow the healther center to offer, at full capacity, the following services to the disadvantaged of our community, including: sliding fee scale for medical and mental health services, Indigent Drug
AARA Increases Services to Health Center
Increase Services to Health Centers - Gulf County  The Gulf County Health Department is experiencing an increased demand in services in both new patients and existing patients who are underinsured and uninsured. The Increased Demand for Service
ARRA - Increase Services to Health Centers - Gulf County
In response to the increase in uninsured and need for primary care services that exist in Westside?s service area, the organization has deemed the best use of funding to be the expansion of its primary care services through the addition of  1.0
The Community Health and Wellness Center of Greater Torrington (CHWC) was established in 2002 by a coalition of concerned citizens and community-based organizations which saw the plight of families from the rural Northwest corner of Connecticut
The purpose of the IDS award is to impact the needs of the community by increasing accessibility to prenatal / postnatal care to expectant women and pediatric care to newborns and other small children.
ARRA - Increase Services to Health Centers The purpose of the IDS award is to impact the needs of the community by increasing accessibility to prenatal / postnatal care to expectant women and pediatric care to newborns and other small children.
C.W. WILLIAMS COMMUNITY HEALTH CENTER, THE INC.
). It is the practice of our Center to pair MOA's with providers. This position can increase the productivity of the provider. Provides support to providers and nurses by anticipating needs and providing assistance in the provision of care.  Pe
ARRA-Increased Demand for Services PrimeCare Community Health Inc. will expand primary and behavioral health care services to those who do not have a medical home. PrimeCare Community Health's target population of 235,986 consists of four disti
ARRA - Increase Services to Health Centers (IDS)  The purpose of this grant was to provide funds for the hiring of 5 new primary care medical providers, three new and two retained positions, along with the suppport staff that support those prov
IDS - Increase Services to Health Centers
StayWell Health Center has been awarded funds to support increased utilization by patients who are newly uninsured or under-insured.
These grant funds support increased demand for services (IDS).  The funds will be used to cover spikes in demand to serve the uninsured populations. The funds are also used to purchase an autoclave statim 5000 for $4,782.44.
The discovery of the Toll-Like Receptor Proteins (TLRs) and their importance in the regulation of host response to infection has led to a series of investigations related to the role of host proteins and cytokines in microbial pathogenesis. Rec
Innate Immunity and Herpes Simplex Infection
The Consortium for Health Education, Economic Empowerment and Research (CHEER) NCMHD Exploratory Center of Excellence has as its primary mission to: engage in community-based collaborations to accomplish research and incorporate the role of com
CHEER:  Transforming Health Disparities into Health Possibilities
Accumulating evidence has indicated that human immunodeficiency virus type 1 (HIV-1) replication is regulated by cell- or virus-derived miRNAs. Recently, we have found that several cellular miRNAs are involved in establishing and maintaining HI
Effect of Cellular MicroRNA's on HIV-1 replication
Tobacco use is mostly initiated during adolescence and we have few effective smoking cessation or prevention strategies for high school aged smokers. This project will develop and test an innovative high-school based intervention that will be d
Incentive-Based Intervention for Smoking Cessation and Prevention in High School
Red cell maturation depends on increased expression of proteins for iron uptake, transport, concentration, and heme synthesis to produce hemoglobin. Ferritin plays a key role in red cells and iron homeostasis: concentrating iron as a mineral an
Ferritin: Protein/mRNA/DNA in Fe/O Regulation/Metabolism
'Chemosensing in the Gastrointestinal Tract'.  Sensing of luminal contents by the gastrointestinal (GI) mucosa plays a critical role in the regulation of digestive functions and protection from harmful substances. The recent discovery that bitt
CHEMOSENSING IN THE GASTROINTESTINAL TRACT
Spatial mapping of human and animal brain function is crucial for the diagnosis of brain disorders, to follow the efficacy of therapy or intervention and to increase scientific knowledge. 17O NMR based mapping can become a fast and robust tool
Cerebral metabolic flux mapping Using Oxygen 17 NMR
Recent evidence implicates that the oxidative stress plays a role in the etiology of Age-Related Cataract, and suggests that aged lens cells are prone to this damage due to reduced expression of antioxidants. Because ocular lens is constantly e
Retinal degenerations are a group of genetically heterogeneous disorders that can often be classified according to the type of pathology observed in rod and cone photoreceptors. These diseases affect one in every 4000 individuals and it is clea
Genetic Modifiers of Photoreceptor Development and Maintenance
Individuals born small for gestational age face severe health problems as children and increased risks as adults of essential hypertension, cardiovascular disease, type 2 diabetes and pregnancy-related hypertension and diabetes. There are two t
Genomics and Epigenomics of Fetal Growth Regulation
Understanding the effects of VEGF augmentation in the developing lung as a method of lung maturation, and defining the contributions of the Nitric Oxide pathway in this process, can pave the way for appropriate therapeutic interventions in the
Role of Angiogenic Agents in Alveolar Maturation and Injury
The plasma level of high density lipoprotein (HDL) is a primary indicator of clinical risk for the onset of atherosclerosis. This property is ascribed to the HDL’s ability to facilitate reverse cholesterol transport (RCT), the major means of
Structure of apolipoprotein A-I on defined states of HDL
The proposed research program will focus on detecting genetic contributions to the two most common conotruncal heart defects, tetralogy of Fallot and d-transposition of the great arteries.  The recent development of array comparative genomic hy
Chromosomal Microdeletions Causing Heart Defects
NOVEL INTERACTIONS OF SLO1 CHANNEL AND THROMBOXANE A2 RECEPTOR IN BLOOD VESSELS . The overall objectives are: 1) To unravel the molecular mechanism(s) of Slo1 channel inhibition by agonist (U46619)-activated Thromboxane A2 receptor and 2) Defin
NOVEL INTERACTIONS OF SLO1 CHANNEL AND THROMBOXANE A2 RECEPTOR IN BLOOD VESSELS
The results of this project will provide crucial information that will improve the effectiveness of Lyme Disease prevention methods directed towards wildlife reservoirs, such as vaccinating wildlife. This project provides a method to identify t
Determining the Reservoir for Host-Targeted control measures to prevent lyme disease
An individual's sensitivity to aversive drug effects is likely to be important not only in the manifestations and course of drug dependence (e.g., in experienced users) but also in the predisposition and/or progression to addiction (e.g., in in
DBH, D2High and Cocaine Paranoia/Aversion: A (11C)PHNO PET Study
These studies will allow us to better understand the molecular basis for individual differences in the response to progesterone in cocaine dependent men and women. Better understanding of these differences will allow us to identify those indivi
Progesterone-Induced gene expression chages and risk of relpase to cocaine use
The goal of the proposed study is to adapt and test the evidence-based collaborative care model (CCM) for homeless women with alcohol use disorders (AUD), including the continuum of risky drinking, abuse and dependence, in a large Health Care f
A Model for Primary Care Management of Alcohol Use Disorders Among Homeless Women
'AMYLOID PLAQUE AND TANGLE IMAGING IN ALZHEIMER'S DISEASE AND DOWN SYNDROME'  Down syndrome is a model for the study of Alzheimer's disease because almost 100% of middle-aged individuals with this condition show a specific pathogenic process th
PLAQUE AND TANGLE IMAGING IN ALZHEIMER'S DISEASE AND DOWN SYNDROME
MOLECULAR ALGORITHMICS FOR PHARMACOLOGICAL INTERVENTIONS This proposal originates from discussions between scientists from different scientific fields: Drosophila aging physiology, information theory, statistics, bioengineering and systems biol
Molecular Algorithmics for Pharmacological Interventions
The study aims to serve as a proof of concept model of individualized medicine in Infectious diseases that will also advance our understanding of innate immunity and chlamydial pathogenesis. The individual differences in susceptibility to vario
System genetics of immune pathways indiced by Chlamydia
PLUNC is a recently discovered protein that is present in high concentrations in the secretions that bathe the respiratory tract. PLUNC is present in all mammals, yet its functions have not been fully elucidated. Our early studies show that PLU
Immune Regulation in the Respiratory Tract by the Epithelial Protein PLUNC
Drugs targeting the HIV virus transcriptase or protease are used in highly active antiretroviral therapy (HAART) cocktails that have prolonged the lives of AIDS patients. Unfortunately, these drugs are associated with severe toxicities, unable
Discovery and Optimization of Novel Integrase Inhibitors as Anti-HIV Agents
Morbidity and mortality associated with severe infections caused by Staphylococcus aureus present a staggering burden on the healthcare in the United States. The increasing antibiotic resistance of S. aureus limits effectiveness of available an
Type I Interferon-Induced Protection from Staphylococcal Pore-Forming Toxins
WESTERN INSTITUTE FOR BIOMEDICAL RESEARCH
Lithium is an effective drug for the treatment of bipolar disorders, which affect about 2-3% of general population and 4-6% of Veterans.  In addition to its long-standing use for the treatment of bipolar disorders, in recent years lithium has b
Potential Therapeutic Applications of Ecto-Nucleotidases in Lithium-induced NDI
In humans, telomeres are repeating strings of TTAGGG DNA sequences at both ends of a chromosome.  While their complete biological functions remain unclear, it is known that telomere lengths shorten gradually and contribute to senescence, apopto
TELOMERE AND ITS BIO-REGULATORS AS PREDICTORS FOR CLINICAL DIABETES IN WOMEN
Title: Cntnap2 in a Behavioral Model of Autism  Impairments in language, social interaction and behavioral flexibility that together occur in young children comprise the hallmarks of autism spectrum disorder (ASD; Geschwind & Levitt, 2007, Curr
Regulation of caspase-1 by Sod2 in the heart?   Apoptosis of cardiomyocytes is increased in human heart failure, and several studies have subsequently suggested that cardiomyocyte apoptosis is a central mechanism in heart failure. The explorato
Regulation of caspase-1 by Sod2 in the heart
The molecular mechanism of antipsychotic drug action is not well understood. Several studies have reported the brain region specific induction of DNA-binding proteins (transcription factors, TF) by these drugs. The functional activity of these
Role of transcription factors in the action of antipsychotic drugs
Therapeutic approach to Autism Spectrum Disorders using TrkB agonists and the molecular mechanisms of TrkB agonist action in human neurons. The overall goal of this proposal is to examine whether TrkB agonist(s) may have therapeutic values for
TRKB AGONIST(S), A POTENTIAL THERAPY FOR AUTISM SPECTRUM DISORDERS
The role of nicotinic receptors in nicotine withdrawal.  Nicotine addiction is one of the primary causes of preventable mortality in the world.  Withdrawal symptoms that occur after nicotine cessation account for the high incidence of relapse i
The Role of Nicotinic Receptors in Nicotine Withdrawal
Genetic architecture of alcohol misuse candidate endophenotypes -  Research Area This application addresses broad Challenge Area 03) Biomarker Discovery and Validation; specific Challenge Topic 03-AA-101,Identification of Intermediate Phenotypi
Genetic Architecture of alcohol misuse candidate endophenotypes
This application addresses broad Challenge Area: (01) 'Behavior, Behavior Change, and Prevention' and Specific Challenge Topic: 01-AR-101 'Integrating Behavioral and Biomedical Research Approaches in Arthritis and Musculoskeletal Diseases' Pati
Chronic Sleep Restriction Increases Immunity to Autoantigen: Role of the SNS
Our Broad Challenge is to develop enabling technologies for the prevention and treatment of diseases affecting the bladder. The Proof of Concept that we are testing is that intravesical instillation of small interference RNA (siRNA) packaged in
Targeted siRNA Nanotechnology for Intravesical Treatment of Urological Diseases
Our overall goal is to create a 3-dimensional tissue culture model amenable to high throughput screening (HTS), and perform a screen on large libraries of chemical agents. We initially carried out proof-of-concept screens with characterized and
High throughput screening in human 3D spheroids of epithelial,endothelial and stromal cells
Using forward genetics in zebrafish and pedigree/patient DNA sequence analysis in humans, we will identify complex genetic interactions that contribute to phenotypes associated with primary open angle glaucoma. The glaucomas are a group of visi
Forward Genetics to Identify Complex Gene Interactions Involved in Glaucoma
Project Title: Economic Consequences of Advanced Testing for Subclinical Cardiovascular Disease The current application is written as a response to requests for applications in the area of NIH Challenge Grants in Health and Science Research (RC
Economic Consequences of Subclinical Disease testi
Calcification of the medial layer of arteries is common in patients with chronic kidney disease (CKD) and correlates with cardiovascular events and death. Research in our laboratories has demonstrated that vascular calcification is normally inh
Leads and Target Validation for Vascular Calcification in Chronic Kidney Disease
) that tests a novel 10- session home-based intervention to treat depression in older community-dwelling African Americans. The intervention, referred to as Beat the Blues (BTB), involves trained social workers who meet with participants to ide
Cost Effectiveness of a Home Support Program for Depression in Black Elders
The ubiquitin system of protein modification permeates every field in biology and is intimately linked to the most prevalent human diseases, including cancer, neurodegeneration, inflammation, and viral infections. With ~30 E2s and an estimated
Comprehensive proteomic profiling of the ubiquitin pathway in cancer
This proposal describes a stable isotope analytical core to support world-wide research in human metabolic studies. The core offers routine and specialized sample analysis on a minimal fee-for-service basis. In addition, it will provide assista
RC2 GO GRANT - Stable Isotope Analytical Core for Studies in Human Metabolism
Full Human Genome Sequencing in ALS - The causes of most neurodegenerative disorders (ALS, Alzheimer and Parkinson disease) are poorly understood, despite remarkable advances in delineating the molecular pathology in the rare forms of these dis
The Scholarships for Disadvantaged Students program provides scholarships to full-time, financially needy students from disadvantaged backgrounds, enrolled in health professions and nursing programs. Participating schools are responsible for se
ARRA – Scholarships for Disadvantaged Students American Recovery and Reinvestment Act of 2009 (Recovery Act) promotes diversity among health professions students and practitioners by providing scholarships for students from disadvantaged back
ARRA Scholarships for Disadvantaged Students
Scholarships for disadvantaged undergraduate nursing students.
UNIVERISTY OF MISSISSIPPI MEDICAL CENTER
Scholarships for disadvantaged students - SDS Med Tech, SDS PT, SDS Medical, SDS Dental, SDS Nursing, SDS Grad Nursing, SDS Dental Hygiene, and SDS OT
This funding represents an increased distribution to the Scholarship for Disadvantaged Students (SDS) program.  This program provides scholarships to students in the health professions (i.e., HMS MD, DMD students) from disadvantaged backgrounds
IMPERIAL COMMUNITY COLLEGE DISTRICT (INC)
ARRA - State Primary Care Offices - This grant assists Primary Care Offices in coordinating activities with states as it relates to the delivery of primary care services and the recruitment and retention of critical healthcare providers.
Upgrade the Garage/Shop building to meet seismic requirements as discovered by Seismic Evaluation performed in 2003.  Design Build, design specific retrofits to correct identified deficiencies and then construct those retrofits.
Funds are to cover structural repairs to upper level replace windows, Paint exterior, install new exterior doors and other updates which will extend the life of building and to make our clinic more energy efficient.  We are also renovating exis
IHS clinic structural repairs/ IHS renovations for pharmacy and dental services
Resurfacing from North of Catoctin Hollow Road to MD 26 Bridge 100097
The overall purpose of this award is to determine how respiratory viruses cause inflammation.  By identifying host factors leading to inflammation upon virus infection, novel therapies to reduce the extent of viral disease may be developed.  Ad
Inflammasome activation by a respiratory virus
Tropical malaria, caused by the parasite Plasmodium falciparum, is responsible for up to three million deaths each year. Since the parasite develops resistance against most clinically available drugs, novel antimalarial drugs are urgently neede
IDENTIFICATION OF G6PD INHIBITORS FOR THE DEVELOPMENT OF NOVEL ANTIMALARIAL DRUGS
Immunological memory at the mucosa must be carefully balanced to ensure long-term protection from re-current infection without excessive immune activation which could lead to chronic inflammation and disease. The intestinal mucosa is a unique n
Regulation of mucosal memory CD8 T cells by Thymic Stromal Lymphopoietin
Coverdell Building for Biomedical Research
Infants are particularly susceptible to respiratory infections which have been attributed to an immature and naive immune system that is characterized by suboptimal antigen presentation and a T helper cell bias toward Th2-type cytokines. Howeve
Host defense against influenza virus in the lungs of neonatal mice
This proposal uses knowledge gained from extensive research into the activity of the influenza virus NS1 protein, to devise a strategy that will lead to the discovery of new influenza virus drug candidates. It is widely acknowledged that the co
INHIBITION OF INFLUENZA VIRUS NS1 FUNCTION BY SMALL MOLECULES
Trichomoniasis is the most common non-viral STD, estimated to cause ~174 million infections world-wide each year. The Trichomonas vaginalis parasite resides in the urogenital tract of both sexes and can cause vaginitis in women and urethritis a
Advancing research on the sexually transmitted female 'nuisance' pathogen Trichomonas vaginalis
and the risk of secondary bacterial pneumonia, which is the major cause of death secondary to influenza. It is our goal to have a nanoparticle mediated novel antiviral prophylactic and therapeutic strategy at the completion of the R33 phase av
ARRA:  Influenza Therapy by Au-nanorod 5'PPP-NS1-siRNA/cDNA Targeting of Bronchial Cells
Candida albicans is an important opportunistic fungal pathogen that causes both mucosal and invasive disease in immunocompromised patients. Nearly all HIV/AIDS patients will develop oropharyngeal (OPC) or esophageal candidiasis during their lif
SYNTHETIC GENETIC ANALYSIS OF THE RAM NETWORK IN C. ALBICANS
Placental regulatory T cells (Tregs) are centrally-important in the maintenance of pregnancy because their immunosuppressive function allows maternal immune tolerance to the semi-allogeneic fetus. HIV infection may result in increased rates of
Placental Treg Activation and Pregnancy Outcome in the FIV-infected Cat Model
The  central  goal of our work  is  to  use embryonic  stem  (ES)  cells  as  a  source  from which  to derive therapeutically relevant skeletal progenitor cells to treat conditions associated with bone and cartilage  damage.  The  field  of  c
EMBRYONIC STEM CELL MODELS TO STUDY THE AXIAL SKELETAL LINEAGE
The overall purpose of the award to study the effectiveness of combining two known stimulators of bone healing - Bone Morphogenetic Protein 2 and Low Intensity Pulsed Ultrasound - in a clinical relevant model of orthopedic trauma. While either
Combined Use of BMP-2 and Low Intensity Pulsed Ultrasound in Bone Regeneration
Musculoskeletal & Connective Tissue Diseases Research
This proposal builds upon work suggesting that the herbal extract Scutellaria baicalensis (SbE) and its major component baicalein may simulate many important components of cardiac preconditioning (PC), i.e. trigger transient mitochondrial oxida
HERB-INDUCED OXIDANT PRECONDITIONING IN CARDIOMYOCYTES
Real time quantitative multiplex analysis of cell-cell interactions, Award number: R21CA128718-01-A2, The objective of this award is the development of a platform for the parallel and time dependent analysis of cell-cell communication. The devi
REAL TIME QUANTITATIVE MULTIPLEX ANALYSIS OF CELL-CELL INTERACTIONS
Proteins play major roles as biological effectors and diagnostic markers. One level of its complexity is due to the post-translational modifications that cannot be detected at the genome level, which makes it desirable to measure proteins direc
NONPARAMETRIC ANALYSIS OF REVERSE-PHASE PROTEIN LYSATE ARRAY DATA
Historically, the aryl hydrocarbon receptor (AhR) has been studied for its transcriptional regulation of genes encoding cytochrome P450 enzymes, which metabolize environmental and endogenous substrates into toxic and mutagenic intermediates. Ac
Antagonism of the Ah Receptor in Controlling for Breast Cancer Growth and Invasion
Chronic Hepatitis B virus (HBV) infection is linked to hepatocellular carcinoma (HCC). The HBV X protein (pX) is implicated in HCC pathogenesis by an unknown mechanism. The long term goals of this study are to determine how pX initiates hepatoc
Role of Polo-like Kinase (Plk-1) in Hepatitis Car
The primary goal of this project is to evaluate the role of FDG PET and its ability to predict early treatment response and drug resistance in advanced epithelial ovarian cancer (AOC).  A vast majority of ovarian cancer patients present with ad
FDG PET AND BIOMARKERS IN TREATMENT RESPONSE IN ADVANCED OVARIAN CANCER
Epigenetic silencing plays a major role in cancer formation because it leads to aberrant inactivation of tumor suppressor genes. Therefore, a fundamental goal for cancer prevention is to inhibit aberrant silencing in somatic cells. Diet provide
A Mouse Model for Dietary Effects on Epigenetic Silencing
Head and neck cancers (HNC) are the sixth most common form of cancer worldwide, with over 500,000 new cases diagnosed annually. Although advances in surgery, and combined of radio and chemotherapies, have decreased morbidity, the survival rate
Anti-tumor properties of curcumin in oral cancers: role of thioredoxin reductase
The proposed research study responds to an unmet need for the successful implementation and dissemination of evidence-based tobacco cessation care for the uninsured. The overall intent of this research is to ultimately close the gap between res
IMPLEMENTATION AND DISSEMINATION OF TOBACCO CESSATION STRATEGIES IN FREE CLINICS
Attaining control over specific neural processes can enable people to influence associated perceptions, behaviors, and cognitions, with potential clinical application to a range of brain- based disorders, including substance abuse (SA). Using r
LEARNED CONTROL OF FRONTAL AND LIMBIC SYSTEMS VIA REALTIMEFMRI
This project will refine an intervention to reduce sexual and injection risk behaviors that lead to infection with HIV and other sexually transmitted infections (STIs) and the hepatitis C virus (HCV) for use in rural areas.  The intervention fe
A Tailored Cue-Card HIV/STI Intervention for High Risk Groups Pilot Study
Schizophrenia is associated with an unusually high rate of cigarette smoking. Smokers with schizophrenia have low quit rates, even when they are motivated to quit and enroll in highly-supportive treatments. The overall aim of this research prog
SMOKING ABSTINENCE AND LAPSE EFFECTS IN SMOKERS WITH SCHIZOPHRENIA AND CONTROLS
Imposing delay between a behavior and its reinforcer weakens the effectiveness of that reinforcer and decreases its subjective value, a phenomenon referred to as temporal discounting.  There is a well-established mathematical model, the hyperbo
Temporal Discounting of Punishment of Drug Choice
The mammalian circadian timing system contains both a light- and food-entrainable oscillator, located in the suprachiasmatic (SCN) and dorsomedial (DMH) hypothalamic nucleus, respectively. Additional studies have suggested the presence of a Met
NEURAL MECHANISMS OF THE METHAMPHETAMINE-SENSITIVE CIRCADIAN OSCILLATOR
Language acquisition, performance in school, and social interactions all require the ability to compensate for the enormous amount of variability in the speech signal introduced by differences across talkers in native language, dialect, age, ge
Children's perception of foreign-accented speech
Bisphosphonates are the most common treatment for osteoporosis. In the last few years, increasing reports of osteonecrosis of the jaw (ONJ) have raised considerable concerns regarding the long-term safety of these agents. The case reports have
Osteonecrosis of the Jaw in Non-Cancer Patients Using Bisphosphonates
This R21 2-year grant will test our hypothesis that the urine proteome of IgAN patients contains disease-specific biomarkers. We aim to develop a non-invasive procedure for screening and monitoring patients with IgA nephropathy by identifying u
URINARY POLYPEPTIDE BIOMARKERS OF IGA NEPHROPATHY
Chronic renal allograft survival is poorer in African Americans than Caucasians which may be due to medication non-adherence, racial differences in immunosuppressive pharmacokinetics, genomic factors, increased immunoreactivity, and racial vari
ARRA: Genomic and Cellular Markers and Chronic Renal Allograft Function
The proportion of individuals with advanced chronic kidney disease who undergo chronic peritoneal dialysis (CPD) treatment, currently <8% of the 400,000 dialysis patients in the USA, has been declining steadily in the past several years. Howeve
Understanding Sources of Bias and Outcomes in Peritoneal Dialysis Patient Research
Hypertension is a major cause of morbidity and mortality in the United States, especially in the African American population where the prevalence, consequences, and severity of hypertension are at their highest; making strategies for its contro
K-Mg-Citrate as Blood Pressure Lowering Agent in African Americans: Role of Natriuresuis - ARRA Stimulus Funding
This project is to evaluate the roles of beta cell antigens presented by dendritic cells in the immunotherapy for type 1 diabetes (T1D), T1D mouse model NOD mice are used in the whole project. The objective is to develop optimal approaches for
Integrating Beta Cell Antigenic Epitopes into DC-Based T1D Immunotheraphy
This study aims to compare the effectiveness of traditional behavioral therapy (based on Brownell's LEARN program for weight management, 2000) with acceptance-based therapy (based on the behavioral and nutritional components of LEARN) for weigh
Acceptance-based Behavior Treatment:  An Innovative Weight Control Intervention
GEORGIA HEALTH SCIENCES UNIVERSITY RESEARCH INSTITUTE, INC.
: The long-term aim of to limit disease in man. Toward this goal, we will take advantage of: the restricted nature of 13(IV) collagen (13(IV) and its available epitopes with the kidney; the availability of a unique panel of human monoclonal ant
MODIFIED HUMAN ANTI-A(3) IV ANTIBODIES FOR DRUG DELIVERY IN NEPHRITIS
BRENTWOOD BIOMEDICAL RESEARCH INSTITUTE, INC.
The purpose is to delevop and characterize an in vitro system for measurement of dudenal bicarbonate secretion.
An in vitro system to measure intestinal bicarbonate secretion
DESCRIPTION (provided by applicant): Exploring Specific Metabolic Rates of Major Cell Categories in Adiposity-Diverse Adults ABSTRACT Obesity is a significant health problem in the USA. Previous studies observed that obese adults have greater r
Exploring Specific Metabolic Rates of Major Cell Categories in Adiposity-Diverse Adults
The purpose of this protocol is to investigate the central nervous system dysfunction that is associated with chronic pelvic pain and also a possible novel treatment using a neuromodulatory tool - transcranial direct current stimulation (tDCS)
INVESTIGATION AND TREATMENT OF CENTRAL NERVOUS SYSTEM DYSFUNCTION IN CHRONIC PELV
DESCRIPTION (provided by applicant): While erythropoietin (Epo) is commonly used to treat anemia in patients with cancer and kidney disease, recent studies have raised major safety concerns. There is great interest in developing new strategies
ARRA Novel Erythroid Cell Membrane Protein
Childhood obesity is a formidable health threat, with 1 in 3 American children overweight or obese. Innovative approaches are needed to reverse this epidemic and prevent related complications such as type 2 diabetes and high blood pressure. Def
Epicardial Contribution to the Developing and Postnatal Heart
This is a pilot study to establish a profile of oxidative stress among participants in the Epidemiology of Diabetes Complications (EDC) study to assess whether the degree to which an individual is able to respond to oxidative stress modifies th
Oxidative Insults, Antioxidative Responses and Type 1 Diabetes Complications
RESEARCH INSTITUTE AT NATIONWIDE CHILDREN'S HOSPITAL
Good glycemic control clearly prevents diabetic complications and decreases the risk of heart disease in patients with type 1 diabetes. However, it is unclear how acute and short-term variations affect precursor to diabetic complications. For i
Endothelial Function Predictors in Adolescent Diabetes
PALO ALTO INSTITUTE FOR RESEARCH AND EDUCATION, INC.
Conventional dialysis provides limited clearance of organic solutes that accumulate when the kidneys fail.  Numerous studies are therefore examining the effects of increasing dialysis frequency and duration.  An alternate approach would be to r
The Production of Uremic Solutes by Colon Microbes
One-fifth of the genome codes for secretory proteins; a small subset of these proteins represent peptide hormone signaling molecules. This proposal addresses the identification of novel secretory molecules involved in the control of metabolic f
Identification of Novel Peptide Hormones
HUGO W. MOSER RESEARCH INSTITUTE AT KENNEDY KRIEGER, INC.
Relationship of MRI to ASIA Impairment Scale in Chronic Spinal Cord Injury.  The objective of this investigation is two-fold: 1) to add to the classification value of the American Spinal Injury Association (ASIA) Impairment Scale by establishin
Relationship of MRI to ASIA Impairment Scale in Chronic Spinal Cord Injury
Role of the Aryl hydrocarbon receptor (AhR) and RelB during the initiation of dendritic cell differentiation. The present study focuses on a new mechanism of cross talk between AhR and the NF-?B member RelB (alternative AhR/RelB pathway), which
Role of the Aryl hydrocarbon receptor (AhR) and RelB during the initiation of dendritic cell differentiation
Vascular toxicities of environmental tobacco particulates in children:  The objective of this study is to define the relationship between environmental tobacco smoke, obesity, and blood vessel function in children.  A result of theis study will
Vascular toxicities of environmental tobacco particulates in children
Bacterial keratitis is a major cause of ocular surface morbidity that often leads to permanently compromised visual function, somethings to an extent that necessitates corneal transplantation to resture adequate vision.  Often the bacterial str
Nanoscale Presentation of Antimicrobial Peptides found at the Ocular Surface
DESCRIPTION: This proposal focuses on the application of therapeutic ultrasound in improving ocular drug delivery. The proposed research will address an important clinical problem since it is often difficult to achieve therapeutic levels of dru
Smad3 plays a central role in the TGF?-mediated fibrosis with characteristic inflammation, proliferation and transformation of fibroblasts and epithelial-to- mesenchymal transition. Gene therapy and small chemicals targeting Smad3 signaling hav
Smad3 Inhibitors for Ophthalmic Applications
G8pos skeletal muscle stem/progenitor cells may provide the source of ?-smooth muscle actin positive myofibroblasts detected in lens fibrotic diseases. We hypothesize that disruption of the G8pos epiblast-skeletal muscle stem cell niche, such
The Stem Cell Niche and Lens Fibrotic Disease
Fertility and Oral Contraceptive Use Study (FOCUS)  Oral contraceptives (OCs) are the most popular reversible method of contraception in the US.  Although most women using OCs experience reliable protection against pregnancy, nearly half of the
Fertility and Oral Contraceptive Use Study (FOCUS)
Inflammatory Bowel Diseases (IBD) are chronic and unpredictable disorders of the gastrointestinal tract associated with significant morbidity, intrusive medical and surgical interventions, and disability. Incidence of IBD, especially among chil
DEVELOPMENT OF THE PEDIATRIC IBD BEHAVIORAL HEALTH REGISTRY
TEXAS A & M UNIVERSITY SYSTEM HEALTH SCIENCE CENTER RESEARCH
NTDs are a group of common, structural malformation that is associated with excess morbidity and mortality. A specific etiologic agent(s) cannot be identified in the majority of individuals with NTDs, and in this group of patients the condition
GENETIC SUSCEPTIBILITY OF NEURAL TUBE DEFECTS:  DIABETES/OBESITY-RELATED GENES
This study will provide current data designed to develop and test a targeted sexual health intervention among bisexual men, a high risk population for HIV infection and transmission. Scientific outcomes will add to the knowledge base that is la
Premature birth is a major public health problem that causes 70-80% of neonatal morbidity and mortality. To address this problem our research focuses on understanding the hormonal control of labor and in particular how the steroid hormone proge
Genomic Actions of Progesterone Receptors in Human Myometrial Cells
Preterm birth, small-for-gestational age (SGA) and pregnancy induced hypertension (PIH) are major pregnancy complications that impact the health of the mother and the child, often resulting in admission to the neonatal intensive care unit follo
MATERNAL GENETIC VARIATION AND RISK OF ADVERSE PREGNANCY OUTCOMES
Data on the effects of omega-3 fatty acids (n-3 FA) on cardiovascular risk are inconsistent. Some observational studies and randomized trials have suggested that n-3 FA may lower the risk of sudden cardiac death (SCD) and coronary events, possi
Red Blood Cell Omega-3 Fatty Acids and Coronary Artery Disease
Obesity is a burgeoning public health problem that is associated with an adverse metabolic profile and higher levels of morbidity and mortality from multiple causes. Current methods for assessing obesity focus on either nonspecific measures of
A PROSPECTIVE STUDY OF ADIPOSITY AND SUBCLINICAL CORONARY ARTERY DISEASE
An ideal therapy for genetic blood diseases would correct defective genes in the patient's own hematopoietic stem cells (HSC). Homologous recombination (HR) can, in principle, achieve this; however, its practicality is restricted by the scarcit
Targeted Gene Correction in Multipotent Hematopoietic Cells
Birth Defects & Genetic Diseases Research
This two-year proposal describes the development of functional lymphatic networks and their integration into artificial dermal constructs in vitro. While many methods have been developed to form microvascular networks suitable for perfusion of
ENGINEERING FUNCTIONAL LYMPHATIC NETWORKS IN VITRO
In August 2011, the second manuscript for this project was accepted for publication in the Journal of Autoimmunity.  The article entitled “Antigenic Challenge in the Etiology of Autoimmune Disease in Women” will be published in a special is
BLOOD TRANSFUSIONS: GENDER DIFFERENCES IN UTILIZATION, PREDICTORS, AND OUTCOMES
A variety of novel nanomaterials have recently been developed with primary in vivo distribution to macrophages and macrophage subtypes. These materials have been used for the diagnosis of diseases where macrophages play a critical role in patho
Multimodal nanoagents for the detection and treatment of atherosclerosis
Advances in medical monitoring have failed to improve outcomes and significantly impact medical decision making by bedside clinicians, particularly in the acute care setting.  Computerized decision support technologies based on quantitative, me
Quantitative, Model-Based Medical Decision Support by Bayesian Inference
The long-term objective of the application is to understand how emotional experiences alter memory acquisition and consolidation processes in the forebrain. The PI was instrumental in developing recent technological advances that allow powerful
EMOTIONAL LEARNING-INDUCED CHANGES OF NEURONAL REPRESENTATIONS IN THE HIPPOCAMPAL
Disturbances in maternal care have been associated with impairments in affective and cognitive development of the offspring. In humans, there is growing evidence that postpartum mood disorders have a negative impact on the mother-child relation
MATERNAL BEHAVIOR AND EFFECTS OF PATERNAL AFFILIATION IN 5-HT1A OVEREXPRESSING MI
To support the study to identify psychological and behavioral factors that help prevent gay fathers from HIV risk, substance abuse, and psychological distress as they navigate the myriad life-changing situations faced as parents.
Description of the ARRA-funded project: The overarching goal of this proposal is to evaluate a potentially unifying psychobiological mechanism underlying social deficits and restricted repetitive behaviors (RRBs) in autism.  The potential ultim
Emotion-Modulated Psychophysiology of Autism Spectrum Disorders (ARRA)
People/Families with of People with Developmental Disabilities
Dose of Early Therapeutic Mobility: Does Type and Frequency of Activity Matter? Abstract Early therapeutic mobility (ETM) activity has been recommended to facilitate recovery and improve outcomes, particularly for the one million survivors of c
Dose of Early Therapeutic Mobility: Does Type or Frequency of Activity
DESCRIPTION (provided by applicant): The vertebrate central nervous system (CNS) is patterned by environmental signals that regulate neuronal phenotype and function. Understanding the mechanism of cell differentiation in the nervous system is v
WNT TARGETS IN HYPOTHALAMIC NEUROGENESIS
In humans uric acid constitutes a strong antioxidant as well as the end product of purine metabolism. Lower blood uric acid is now emerging as a major molecular risk factor for idiopathic Parkinson's disease (PD). Moreover, our preliminary find
Uric acid: novel therapeutic target for Parkinson's disease
The ultimate goal of this project is to develop Positron Emission Tomography (PET) imaging agents to measure the level of vesicular acetylcholine transporter (VAChT) expression in the human brain. VAChT is a unique and novel marker for choliner
DEVELOPMENT OF VESICULAR ACETYLCHOLINE TRANSPORTER IMAGING AGENTS FOR PET
Neuroimaging techniques such as MRI, fMRI and PET provide a wealth of quantitative information related to anatomy, function, development, and disease etiology of the nervous system. Experimental studies utilizing neuroimaging techniques have ge
NeurolE:  a Tool for Mining the Neuroanatomic Volumetric Literature
This project is being supported with funds from the American Recovery and Reinvestment Act, which may involve a reduction in the research aims and scope. If necessary, a revised abstract will be posted soon and this notice removed.  DESCRIPTIO
ARRA A forward genetic approach to studying glioma formation and therapy resistance
Given our long-term goal to discover new therapeutic approaches that can improve patient outcomes, we will investigate a nove therapeutic strategy, intranasal drug delivery, aiming to inhibit the invasion of glioma cells. The proposed studies a
Intranasal Drug Delivery to Inhibit Glioma Angiogenesis and Invasion
Ample evidence suggests that a dramatic decrease in mitochondrial Ca2+ retention may contribute to cell death associated with stroke, excitotoxicity, ischemia and reperfusion, and neurodegenerative diseases. Mitochondria from all known tissues
Molecular mechanisms of Ca2+ retention in mitochondria
Myostatin (MSTN) is a secreted protein that normally acts to suppress muscle growth. Mice genetically engineered to lack MSTN activity have dramatic increases in muscle mass as a result of a combination of muscle fiber hypertrophy and increased
INHIBITORS OF BMP-1/TLD PROTEASES AS NOVEL THERAPEUTICS FOR MUSCULAR DYSTROPHY
as we have already worked-up the biochemical composition of the venom of these snails and immediate correlations between activity and structure can be drawn.  Our ultimate goal is to augment the current library of conotoxins with known activit
Efficacious Screening of Peptidic Natural Products using Drosophila
The juvenile onset form of Batten disease (Juvenile Neuronal Ceroid Lipofuscinosis, JNCL), a fatal neurodegenerative disorder, results from mutations in the CLN3 gene. No specific treatment is currently available that could halt or slow the pro
AMPA receptor attenuation as a new therapeutic approach for Batten disease
After injury, unlike the axons of the central nervous system where the regeneration process is poor or absent, axons of the peripheral nervous system are able to regenerate, though inefficiently. Uncovering the molecular mechanisms behind axon
Microfluidic-microtiter interface for rapid large-scale screenings of C. elegans
DESCRIPTION (provided by applicant): We propose to conduct a first-ever comprehensive quantitative investigation of motor function in autism using simultaneous brain and movement imaging. A novel system developed by Co- Investigator Makeig and
Pupillary light reflex (PLR) is a simple objective measure of neurological functions. Our preliminary study has revealed that individuals with autism show significantly longer constriction latencies and smaller constriction amplitudes. The prop
Validation study of atypical dynamic pupillary light reflex as a biomarker for autism
DESCRIPTION (provided by applicant): Nanopores have shown great promise for DNA sequencing, and more recently as instruments for probing interactions between DNA and DNA-binding enzymes. The broad aim of the proposed research is to develop a na
A NANOPORE-BASED INSTRUMENT FOR SINGLE MOLECULE ANALYSIS OF DNA-BINDING PROTEINS
The mouse is an invaluable tool for modeling human disease. The tremendous power of the mouse is due in part to our ability to manipulate its genome in a precise manner, and our toolbox to perform these tasks is rapidly expanding. As part of Th
ENHANCING THE UTILITY OF CRE DRIVER LINES
The Neuronal Ceroid Lipofuscinoses (NCL) is probably the most frequent group of progressive inherited neurodegenerative diseases with childhood onset. They can start at all ages and progression is characterized by one or more of the following s
ARE NCLS ATYPICAL IN LATIN AMERICA? PHENOTYPIC AND GENOTYPIC ANALYSES.
The Physical Activity Partnership for Girls seeks to build a strong community-academic partnership in order to investigate community priorities and needs for physical activity promotion among Latino adolescent girls (age 11-14 years) in Westsid
PARTNERSHIP TO ADDRESS PHYSICAL ACTIVITY AMONG LOW-INCOME LATINO ADOLESCENT GIRLS
Bipolar disorder is a severe debilitating mental illness affecting over three and half million Americans. This illness crosses all gender and ethnic boundaries to cause extensive morbidly and mortality. With this tremendous burden on the patien
As part of public health efforts to curtail drug use and associated behaviors, secondary students must understand that addiction is a brain disease that results from drug-induced changes in the cellular processes mediating learning in the brain
Changing Brains Through Inquiry, Not Drugs
The goal of these studies is to determine the mechanisms utilized by mouse and human neutrophils to control helminth infections. Previous studies have demonstrated that neutrophils are required for killing larval Strongyloides stercoralis in na
Neutrophil Dependent Immunity to Strongyloides Steracoralis
The importance of T cells in the pathogenesis of asthma and other allergic diseases is undisputed.  The extend of the T cell respose is tightly controlled by a variety of homeostatic mechanisms.  T regulatory cells (Tregs) represent a major hom
Mechanism of T Cell Resistance Against Treg-mediated Suppression in Asthma
facultative chromatin over the transcription initiation site. Our experimental approach will focus on silenced IL-1? and TNF?, and transcribed I??? and employ genetic and biochemical analysis.
Epigenetics of Severe Systemic Inflammation
M. tuberculosis (Mtb) has caused a global health emergency. Yet little new chemotherapy against Mtb has emerged in decades. This application aims to target a pathway in the pathogen that is not essential for the pathogen to survive in vitro but
The objective of this work is to determine how a Mycobacterial secretion apparatus called ESX-1 plays critical roles in important, but apparently disparate, molecular processes: conjugal DNA transfer and virulence. The proposed studies will elu
MOLECULAR DISSECTION OF CONJUGATION, VIRULENCE AND ESX SECRETION IN MYCOBACTERIA
In a region of the world like West-Central Africa where multiple HIV-1 groups and subtypes co-circulate, the rate of dual infection -the concomitant or sequential infection with two or more geneticallly distinct HIV-1 strains- is frequent and r
Viral Evolution and Humoral Immune Response to Dual HIV-1 Infection
This proposal outlines a comprehensive plan to genetically dissect the fatty acid metabolism of the human pathogen Toxoplasma gondii. T. gondii infection is widespread in the U.S. (22% of the population is chronically infected) and while usuall
Genetic dissection of parasite metabolism
A one-year NIH R56 (Bridge Award) grant to Dr. Henry Murray to support his continued laboratory research in the treatment of leishmaniasis, a parasitic infection. Expected outcome are:  (a) the generation of new scientific results in experiment
are a very large family of multidrug transporters in bacteria, fungi and plants. Despite their biological importance, and their clinical importance in humans, virtually nothing is known about the structure of these transporters, or of the infl
Molecular Organization of the Organic cation-Proton Exchanger, MATE1
The mTOR  (mammalian target of rapamycin) and GCN2 [eukaryotic initiation factor 2 alpha (eIF2?) kinase 4] pathways play critical roles in integrating the organism’s response to insulin, growth factors, energy status, and nutrient availabilit
CROSS-TALK BETWEEN GCN2 AND MTOR IN INTEGRATION OF NUTRIENT SIGNALING
Despite extensive evidence implicating excess circulating non-esterified fatty acids (NEFA) in the induction of systemic insulin resistance, the mechanisms underlying elevated plasma NEFA levels remain unclear. Adipose tissue is the largest NEF
The control of fatty acid release in adipocytes
This innovative translational research endeavor will employ an established cue reactivity/exposure methodology to assess the therapeutic potential of an untested and potentially promising adjunctive pharmacotherapy for one of the most prevalent
Treatment Implications of Trauma Memory Modulation for PTSD and Alcohol Dependence
Advancing Diffusion Tensor Imaging and Analyses for Basic Alcohol Research - ARR. The purpose of this project is to rapidly advance DTI technology and its application to discovery and documentation of alcohol’s deleterious effects on the pre-
Advancing Diffusion Tensor Imaging and Analyses for Basic Alcohol Research - ARR
There are no effective treatments for hepatic fibrosis. Thereâ??s an urgent need to develop therapeutic agents that delay/reverse hepatic fibrosis. We believe that PEG-TGF-B peptantagonist should be an ideal candidate for treating human liver
Development of a Novel TGF-beta Antagonist for Treating Hepatic Fibrosis
Interpersonal behavior affects individuals' emotions, arousal, stress, and facilitated or impairs social support, intimacy, and relational satisfaction. This project will deliver new methods and models that allow for more specific articulation
TOOLS FOR ARTICULATING WITHIN-PERSON DYNAMIC MODELS OF INTERPERSONAL INTERA
As the population of the United States ages, there is an increased risk of cognitive impairment and physical deconditioning. Physical exercise has been shown to have physical and health benefits in the elderly and there is increasing evidence t
EXERCISE VERSUS COGNITIVE INTERVENTIONS FOR ELDERS AT RISK FOR DEMENTIA.
Purpose: The principal objective of the proposed research is to define the cellular pathogenic mechanisms of fragile X-associated tremor/ataxia syndrome (FXTAS), one of the leading known single-gene forms of late-onset neurodegeneration. FXTAS
Human iPSC Neuronal Models for Early and Late Phases of FXTAS Neurodegeneration
Most strategies to increase marrow production of platelets have focused on use of positive cytokines such as thrombopoietin (TPO). We have recently described an important inhibitory loop that also regulates platelet counts. We found that at lea
MEGAKARYOCYTE CHEMOKINES & POST-IRRADIATION THROMBOCYTOPENIA
This project, entitled ?Epidemiology and Mechanisms of Accelerated Aging in HIV Infection,? addresses broad Challenge Area (05) Comparative Effectiveness Research and specific Challenge Topic, 05-AI-101: Accelerated Aging in Treated vs. Untreat
EPIDEMIOLOGY AND MECHANISMS OF ACCELERATED AGING IN HIV INFECTION
The development and maintenance of memory T cells is a hallmark of the host response to acute and persistent viral infections and a major objective of vaccination for infectious diseases and cancer.  Progress in defining the qualitative attribu
Analysis of a Novel Subset of Human CD8+ Memory Cells with Stem Cell Qualities
DESCRIPTION (provided by applicant): This application addresses broad Challenge Area (05) Comparative Effectiveness Research, and specific Challenge Topic 05-AI-102: Comparative-effectiveness of Anti Retroviral Therapy (ART). We propose to asse
Comparative effectiveness of ART for HIV in patients with comorbidities
Highly drug resistant forms of tuberculosis termed multidrug resistant (MDR) and extensively drug resistant (XDR) tuberculosis are on the rise worldwide raising the specter that this disease may once again become virtually incurable.
The focus of this grant is to establish Drosophila melanogaster as a model system to study sphingolipid signaling as it relates to muscle regeneration as well as to test a wunen/LPP3 based strategy that suggested itself from our studies in Dros
Generation of Wunen/LPP3-based therapy for muscular dystrophy
DESCRIPTION (provided by applicant): This application addresses broad Challenge Area (06) Enabling Technologies and specific Challenge Topic 06- AT-101*: Imaging correlates of brain states. Project Summary: Our goal is to determine the function
Resting State Functional MRI Investigation of Hypnotic Trance and Mindfulness Meditation
Genome wide association studies (GWAS) are typically carried out to uncoverpotential correlations between SNP genotypes and disease phenotypes. Often,cancer or neoplastic conditions have been the subject of these studies, and theyhave provided
Augmenting GWAS with Retrotransposon Polymorphisms
. Prostate cancer is a highly prevalent disease in older men of the Western world, whose initiation, unregulated growth, invasion and metastasis is characterized by multiple complex events. Gathering genomic, proteomic and metabolomic expressio
INTEGROMICS WITH APPLICATION TO PROSTATE CANCER PROGRESSION
We will perform deep sequencing of small regulatory RNAs expressed in the lymphoma biopsies from 250 patients with diffuse large Bcell lymphoma (DlBCl) and in lymph node biopsies from SO healthy donors, aiming to identify small regulatory RNAs
DEEP SEQUENCING OF SMALL REGULATORY RNAS IN DIFFUSE LARGE B CELL LYMPHOMA
Challenge Grant  1RC1DA028173 “Adolescent Brains, Nicotine and Endogenous Prototoxins” is a new, multidisciplinary project that involves 5 neuroscientists from UVM in the areas of animal behavior, human cognition, and molecular cell biology
Adolescent Brians, Nicotine and Endogenous Prototoxins
Mental Health, Substance Abuse Programs, General/other
The methylation status of DNA influences many biological processes during mammalian development, including retrotransposon silencing, X-inactivation and asymmetric expression of parentally imprinted genes.  In mammalian cells, DNA methylation o
Chemical modulators of Tet-family proteins
Understanding the neural mechanisms of tinnitus. The grant supports personnel and equipment needed to carry out an investigation into the neural activity in the brain that may underly tinnitus. Tinnitus is a phantom sound percept that occurs in
UNDERSTANDING THE NEURAL MECHANISMS RESPONSIBLE FOR TINNITUS
MASSACHUSETTS EYE AND EAR INFIRMARY & PHYSICIAN STAFF, INC.
'Networking of Brain activity in People with Tinnitus'   The proposed work will investigate a completely new brain mechanism for tinnitus directly in people.  This mechanism - abnormal coordination, or coupling, between brain centers - is manif
ARRA-Networking of Brain Activity in People with Tinnitus
Computer Assisted Guidance for Tobacco Dependence Interventions in Dental Offices  Electronic health records (EDR) represent a powerful tool for incorporating best practice guidelines into the dental treatment encounter through the use of clini
Computer Assisted Guidance for Tobacco Dependence Interventions in Dental Offices
This application addresses broad Challenge Area (08) Genomics Topic: 08-DE-103: Epigenomics and Epigenetics of Oral Health and Disease. The standard paradigm for characterization of genome wide epigenetic alteration in human cancers has been fo
INTEGRATIVE PATHWAY ANALYSIS OF EQIGENOMIC/TRANSCRIPTIONAL ALTERATION IN HNSCC
This application addresses broad challenge area (15): Translational Science, and specific Challenge Topic 15-DE-104: Functional Restoration of Salivary Glands. Hypofunction of salivary gland is a common pathological condition in patients with S
Modulating Wnt and Hedgehog Pathways for Functional Restoration of Salivary Gland
The sizable weight losses seen with bariatric surgery are often associated with improvements or resolution of several obesity-related comorbidities, including type 2 diabetes. The proposed project is designed to investigate the mechanism by whi
Lifestyle Modification versus Bariatric Surgery for Type 2 Diabetes
despite full access to integrated health care, and allow healthcare delivery systems to modify their programs to better serve their membership.
Failure to Utilize Diabetes Health Services Following a Referral
This proposal will address core items in Challenge Area 08 (Genomics), specifically targeting Challenge Topic 08-DK-107, Nuclear receptor mediated assembly of functional transcription units. In relation to this application, this Challenge Topic
Genome-Wide Analysis of RXR-alpha Binding in Mouse Liver Chromatin with ChIP-SEQ
This application addresses broad Challenge Area (07) Enhancing Clinical Trials and specific Challenge Topic, 07-DK-103: Support for Registries. Live donor kidney transplantation is the best treatment for kidney failure, doubling life expectancy
DEVELOPMENT OF A NATIONAL INCOMPATIBLE KIDNEY TRANSPLANT REGISTRY
The risk for developing end-stage renal disease (ESRD) in African Americans is more than 3-fold higher than European Americans. This disproportionate risk is apparent for virtually all forms of kidney disease, but only a minor portion can be ex
Genetic Determinants of Susceptibility to Kidney disease in African Americans
The Children's Hospital of Philadelphia (CHOP) contributes substantially to the local economy. In 2008, CHOP's operations created and supported over 16,882 jobs in the region, and CHOP's total economic impact was over $5.9 billion. Moreover, th
CALCINEURIN INHIBITOR MINIMIZATION AND FOXP3+ TREGS POST-TRANSPLANT
Common complications of portal hypertension include gastroesophageal varices, ascites, and portasystemic encephalopathy. Patients with cirrhosis have a 5-10% yearly incidence of variceal formation, and a 4-15% yearly incidence of bleeding. Each
Noninvasive and Accurate Measurement of Portal Hypertension
The use of multimodality PET/CT or SPECT/CT has increased substantially in recent years. The use of both an anatomical imaging modality and a functional one provides an extra image dataset for diagnosis, can improve the reconstruction of the fu
QUANTITATIVE ASSESSMENT OF THE BENEFITS AND RISKS OF CLINICAL PET/CT AND SPECT/CT..
The prevalence of abdominal aortic aneurysms (AAA), has increased significantly, affecting 5-7% of Americans over age 60. Endovascular aneurysm repair has been shown to be a safe and effective treatment for AAA disease. Currently, there are 5 F
Resistance to Aortic Endograft Migration: Comparative Effectiveness of FDA Approv
Environmental toxins, such as the herbicide paraquat, cause neuronal cell death through oxidative stress. Locomotor impairments are sensitive indicators of neurodegeneration. A long-standing challenge in environmental health science is to asses
Oxidative Stress and Neurogenetic Networks in Drosophila
Mounting evidence suggests that environmental exposures, particularly when occurring at a critical developmental window in early life, can profoundly affect the phenotypes associated with complex diseases such as allergic asthma. In particular,
Proteomic Signatures of an Early Life Asthma-Protective Exposure
This application addresses broad Challenge Area (08) Genomics and specific Challenge Topic, 08-ES-104: Identification of alterations in epigenetic marks related to environmental exposures. In the US, over one million people are occupationally e
DNA Methylation Alterations in Response to Pesticide Exposures
Air pollution, particularly O3, induces exacerbations of asthma that substantially worsen morbidity and mortality. In healthy individuals inhalation of O3 elicits mechanisms such as homeostatic increase in SP-D synthesis that protect the lung f
Effects of ozone exposure on expression and function of surfactant protein D
The application of PET to evaluate the health and safety of nanomaterials will offer a deep and broad understanding of nanoparticle behavior, revealing the pathways nanomaterials take in living systems and identifying some of the acute and long
Imaging nanoparticle interactions with living systems
This application addresses broad Challenge Area, (08) Genomics and Specific Challenge Topic, 08-ES-106: The role of environmental exposure in copy number variation (CNV): 'Microscopic deletions and replications of the genome have attracted incr
ENVIRONMENTAL RISK FACTORS FOR COPY NUMBER VARIATION IN HUMAN CHROMOSOMES
REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE
This application addresses broad challenge area (06), Enabling Technologies, and specific Challenge Topic 06-GM-109:  Green chemistry and engineering for drug discovery, development and production.
Enzyme-Mediated Synthesis of Functionalized Terpene Structures
This application addresses broad the Challenge Area (06) Enabling Technologies and Specific Challenge Topic 06-GM-106; subcellular imaging of metal ions. Methods to improve spatial resolution are complex and not always compatible with cell imag
Sub-Wavelength Imaging of Intracellular Metal Ions
Induced pluripotent stem cells (iPSCs) are the most expected cellular sources for regenerative medicine and hold tremendous therapeutic potential. Many groups have shown that adult fibroblasts and epithelial cells can be reprogrammed to a pluri
iPSC Generation using Peptide Injection and Site-Selective HDAC Inhibition
In the work to be supported by this award, we will: 1) Extend the best methodology for imputation to African Americans, producing public-domain software to execute these analyses, validating our methods, and providing a public-domain database o
Enabling Imputation and CNV Analysis in Genetic Studies of African Americans
Motions that contribute to biomolecular recognition occur on all timescales, but in contrast to relatively slow dynamics, which may be characterized by a variety of well developed techniques, there are no techniques thatmay be used to character
DEVELOPING 2D UV/VIS SPECTROSCOPY TOOLS TO STUDY BIOMOLECULAR RECOGNITION
RNA interference (RNAi) functions as an antiviral immunity in fungi, plants, insects and nematodes. In this immunity, dsRNA produced during replication of viral RNA genomes or convergent transcription of viral DNA genomes is processed into 21-
Virus Discovery by Deep Sequencing and Assembly of Virus-derived siRNAs
The challenge addressed in this proposal is to better understand the remarkable increase in the prevalence of atopic diseases (atopic dermatitis (AD), food allergy, asthma, and atopic rhinitis) over the last 4-5 decades and the extent to which
Antenatal Dietary Supplementation is a Risk Factor for Infant Atopy Through Epigenetics
The goal of this project is to generate evidence-based measures of the effectiveness of 65 federally-funded teacher professional development institutes for middle school life science teachers. Such institutes typically meet for a week or longer
ALSISE: Assessment of Life Science Intermediate School Educators
This application addresses Broad Challenge Area (12): Science, Technology, Engineering, and Mathematics (STEM) and Specific Challenge Topic, 01-OD-101: Efficacy of Educational Approaches Toward Promoting STEM. This project will test the efficac
IMPROVING PROBLEM-SOLVING PERFORMANCE OF STUDENTS WITH MATHEMATICS DIFFICULTIES
The proposal has 2 specific aims:   Specific Aim 1: To use versatile reporter gene constructs to understand the biology and physiology of cardiac stem cells in vivo.  Specific Aim 2: To track cell fate in pre-clinical large animal models using
Molecular Imaging of Resident Cardiac Stem Cells
DESCRIPTION (provided by applicant): This application addresses broad Challenge Area (06): Enabling Technologies and specific Challenge Topic, 06-HL-103: Develop new imaging methodologies to track cells and measure accurately the chemical activ
Despite major roles played by heparin and heparan sulfate in growth and morphology, coagulation, angiogenesis, immune response and viral infection, their interaction with nearly all proteins, except for antithrombin, remains poorly defined. The
A Robust Predictive Method for Heparin and Heparan Sulfate Binding to Proteins
Diseases of the Blood & Blood-Forming Organs
Faculty at Case Western Reserve University and its Comprehensive Cancer Center with key collaborators at the University of Kentucky, and University of Minnesota propose to develop a novel stem cell graft engineering approach that will address t
Stem Cell Priming to Enhance Engraftment
This application addresses two broad Challenge Areas and three associated specific Challenge Topics including: i) the broad Challenge Area (06) Enabling Technologies, specific Challenge Topic 06-HL- 105: Develop transgenic animal models that ar
Pathological Evaluation of a Cystic Fibrosis Ferret Model
The overall goal of this study is to develop and validate a novel cell-based  high throughput, high content, vascular health profile analysis that provides a signature for individuals  at high risk for cardiovascular events. A unique biocomputa
Validation of a Vascular Health Profile for Cardiovascular Disease
This application addresses broad Challenge Area #8, Genomics, and specific Challenge Topic 08-HL-101, which seeks to identify causal genetic variants associated with heart, lung, and blood diseases by application of targeted DNA capture and mas
IDENTIFICATION OF DISEASE-CAUSING MUTATIONS IN SCID USING EXOME-WIDE SEQUENCING
This application addresses broad Challenge Are on Clinical Research (04) with the specific challenge on Perform secondary analyses of existing data to answer important clinical and preventive medicine research questions: 04-HL-104.An estimate o
BUILDING DISEASE PREDICTION MODELS BY SYNTHESIS ANALYSIS
This application addresses broad Challenge Area (04) Clinical Research and specific Challenge Topic (04-HL- 103): Assess the role of leukocyte interactions with platelets, erythrocytes, and endothelium in the pathogenesis of heart, lung, and bl
ROLE OF NEUTROPHIL-PLATELET INTERACTIONS IN VASCULAR OCCLUSIVE DISORDERS
T cells develop in the thymus from blood cell progenitors. The identity of molecules that allow some blood cell progenitors to migrate to the thymus is unknown. We propose to identify molecules that support trafficking of progenitors to the thy
Engineering hematopoietic progenitors for efficient migration to the thymus
This application addresses broad Challenge Area (04) Clinical Research, and the specific Challenge Topic, 04-AI-101: Develop novel methods and address key questions in mucosal immunology. The long-term goal of this project is to understand how
The Epileptogenic Effect of Perinateal Hypoxia
DESCRIPTION (provided by applicant): This application addresses Challenge Area 10 and specific Challenge Topic 10-HL- 101*,'Information Technology for Processing Healthcare Data for Research,' specifically to the challenge topic 10-HL-101*, 'De
Improved Estimates of the Comparative Treatment Effects of CABG and PCI
To construct sewer district for Woodlands of Millsboro near Millsboro, DE
Woodlands of Millsboro Sanitary Sewer District
PY344 for Miscellaneous Produts - Comm/Pack Eggs US Grade A Large
CONSTRUCTION OF WASTEWATER TREATMENT FACILITY AND VARIOUS SEWER PROJECTS
Helicopter Services for Alaska Volcano Observatory studies.
Nonscheduled Chartered Passenger Air Transportation
Commissioning services for the Quarry Visitor Center at Dinosaur National Monument in Vernal, Utah.  The commissioning consists of systematically documenting that specified components and systems have been designed, installed and started up pro
This grant supports native fish conservation and restoration in New Mexico.  The Vermejo Park Ranch and other state and private partners have initiated a multi-year effort to restore, conserve, and manage native Rio Grande cutthroat trout in th
Interstate 295 Northbound, Brunswick to Gardiner
Dekalb, Andrew & Buchanan Counties, Route 169
Conduct modernization activities as various Public Housing Communities.  This funding can be expected to result in providing employment for architects and engineers, and construction workers. In addition this funding can be expected to substant
AARA Capital Fund Public Housing Modernization Program
1R - VAN VRANKEN AVE RESURFACING PROJECT
1R - CR28 (CORINTH RD) RESURFACING PROJECT, WARREN COUNTY
US 301 FROM MYRTLE STREET TO DESOTO ROAD
Mandan - Division St NE from Collins Ave to 8th Ave NE
The Public Health Traineeship provides a financial resource to help us attract and retain applicants from disadvantaged and underrepresented groups. PHT ARRA funds will support students with documented extreme financial need. These students pur
EAST TEXAS COMMUNITY HEALTH SERVICES, INC
COLUMBIA RIVER COMMUNITY HEALTH SERVICES
ARRA - Capital Improvement Program:  The overall purpose of the project is to purchase an electronic medical records system, purchase equipment we need but do not have, and replace out dated equipment that is necessary for continued care of our
Grant Name: ARRA - Capital Improvement Program (CIP) #C81CS13640  Award Amount: $891,760  Purpose of Grant: The purpose of the CIP grant is to renovate NCHC's 444 William Street, East Orange, NJ site in order to increase services to Essex Count
IBERIA COMPRHESIVE COM HEALTH CNTR, INC.
Asian Health Services is a nationally recognized community health center model for serving a multiethnic and multilingual population.  While the demand for linguistically and culturally competent services continues to grow, AHS is operating at
ARRA-Capital Improvement Program (CIP) grant for the construction of a new administrative office buidling.  The goal of this project is to alleviate overcrowding at our current administrative site as well as provide addidional space for adminis
The Award will address the immediate need for our community to have access to more effective, high-quality healthcare. This will be accompliahed through the acquisition of new technologically-advanced medical and dental equipment and electronic
Originally, this grant was awarded to expand our facility.  Soil Testing was completed for the building expansion project. Survey, retaining wall and site civil design and rezoning of the property was completed for the expansion.  We purchased
Diet-dependent neurosensory systems modulating health and aging
Tuberculosis (TB) continues to kill millions of people around the world.  New tools to prevent and treat this disease are urgently needed. Iron is an essential metal for all forms of life and most bacterial pathogens including Mycobacterium tub
Characterizing a Novel Hemophore from Pathogenic and Non-Pathogenic Mycobacteria
This Administrative Supplement if for salary support for a graduate research assistant who is a memeber of an under-represented minority in biomedical science.  The research is an extension of the current active project (AI24421) and will entai
Determinants of Borrelia Diversity and Population Structure
C. glabrata is an important opportunistic pathogen causing mucosal infection in healthy individuals and disseminated infection in immunocompromised, primarily hospitalized, patients, responsible for approximately 20% of all candidemias. The Cor
VIRULENCE MECHANISMS IN CANDIDA GLABRATA
Trypanosoma brucei is a group of hemoflagellated parasitic protozoa that causes a fatal disease in humans known as African sleeping sickness and a similar diseases in domestic animals called nagana. The disease is transmitted by an insect vecto
Mitochondrial Targeting and Import of Trypanosome Alternative Oxidase (TAO)
This proposed study will address this increasing health concern by characterizing the bioactive potential of a marine bacterium, Genus Pseudovibrio, isolated from a Caribbean coral that is shown to produce a number of antimicrobials in prelimin
Evaluating Antimicrobial Compounds from Coral-Associated Pseudovibrio Bacteria
The overarching goal of this fellowship application is to provide support for work which will focus on dissecting the structure-function relationships in ribonucleoprotein (RNP) complexes that mediate post-transcriptional gene regulation in vir
Mammalian Reovirus Post-Transcriptional Gene Regulation
One of the most striking effects reported by male and female users of methamphetamine, a highly addictive psychostimulant drug of abuse, is an increase in sexual libido and an insatiable need and urgency for sex. In addition, female methampheta
Methamphetamine enhances the motivation for female rat sexual hehavior
This research seeks to determine the role that extracellular matrix (ECM) plays in the aging of skeletal muscle. Skeletal muscle tissue is maintained via the regenerative capacity of the tissue's resident stem/progenitor cells known as satellit
The role of extracelluar matrix in the aging of skeletal muscle
Low dose oral tolerance is defined as the active suppression of a systemic immune response to a specific antigen by regulatory T cells (Tregs) generated in response to repeated ingestion of that antigen. Though ex- tensively studied, the specif
THE ROLE OF CD8+ CELLS IN THE DEVELOPMENT OF ORAL TOLERANCE
Viral infection significantly impacts all forms of life. Since every virus and bacteriophage requires correct organization of its capsid proteins (CPs), the mechanisms by which these CPs assemble must ultimately be determined in order to devise
Coxsackievirus B (CVB) infection is the most common infectious cause of heart inflammation and can lead to chronic disease and cardiac failure. I have found that CVB3 induces minimal T cell responses in a murine model of infection and this may
Evaluating Dendritic Cell Activation and Function During Coxsackievirus Infection
Widespread resistance to long-used drugs and to newer quinoline-based drugs has prompted the need to better understand malaria parasite biology and pathogenesis. Egress from the infected RBCs by the invasive stage of the malaria parasite is a f
MECHANISM OF MALARIA PARASITE EGRESS FROM ERYTHROCYTES
Methicillin-resistant Staphylococcus aureus (MRSA) infections pose a large threat to public health in the United States, causing nearly 19,000 deaths in 2005. Polymers attached to the surface of S. aureus (wall teichoic acids, WTAs) are require
Discovery of Small Molecules that Restore Methicillin Sensitivity to MRSA
The goal of this project is to understand the process by which the pathogenic bacterium Pseudomonas aeruginosa kills the nematode worm Caenorhabditis elegans. C. elegans has recently been developed as a host model for a number of pathogens. Wor
Mechanism of toxin-mediated bacterial pathogenesis in a worm host model
Investigating host genetic polymorphisms contributing to influenza virus disease  The goal of this project is to identify polymorphic host genes that regulate the susceptibility to influenza virus in the mouse, while assessing the role of Mx1 p
Investigating host genetic polymorphisms contributing to influenza virus disease
Organ transplantation is thus far the only cure for patients with a terminal organ failure. Understanding immunological mechanisms underlying graft tolerance vs. graft rejection is critical in clinical transplantation and improving quality of l
ROLE OF INTERLEUKIN 21 IN THE ALLOGRAFT RESPONSE
BENAROYA RESEARCH INSTITUTE AT VIRGINIA MASON
CD4 T helper cell differentiation is controlled by ‘master’ transcription factors that commit the cell to become a Th1, Th2 or Th17 cell or a Treg. It was previously believed that the expression of these transcription factors was mutually e
Epigenetic control of the T-bet Transcriptome by Foxp3 in Tregs expressing T-bet
Our long-term objectives are to understand the evolution of arboviruses in the context of their transmission cycles and how this impacts viral emergence, adaptation and persistence. WNV genetic diversity is greater in mosquitoes than birds in b
THE ROLE OF RNA INTERFERENCE IN WEST NILE VIRUS DIVERSIFICATION
DESCRIPTION (provided by applicant): Many pathogens utilize clonal variation to diversify their antigenic or virulence factors to promote infection, a process termed virulence modulation (VMO). The aims presented within this application will se
Regulation of phenotypic variation in Xenorhabdus nematophila
The purpose of this project is to explore the effects of antigen exposure on T cell quantity and quality in mucosal tissues. This award will result in furthering our knowledge in the above topic as well as foster the further education and suppo
Effect of Antigen Exposure on T Cell Quantity and Quality in Mucosal Tissue
for decontamination of materiel to be moved into the barrier animal facility portion of the Biotech Center.   3.To enhance the capacity to store supplies in the animal facility by the conversion of an under-utilized office area into a storage
Biotech Center Barrier Improvement Project
The ARRA State Loan Repayment Program is a Federal-State partnership that assists States in addressing health professional shortages that cause disparities in access to health care.  This program provides educational loan repayment to primary c
Increasing access to primary health care services and reducing health disparities are the overall purpose of the IDS grant.   With ARRA IDS funding, the Guam CHCs aims to provide medical and ancillary services to 1,590 new unduplicated patients
IDS project addresses the increased need for health services in the Greater Lafayette community and serve uninsured, low-income adults by increasing provider/clinical support and staffing, extending hours of operation, and expanding existing se
ARRA - BPHC - Increase Demand for Services (IDS) for Community Health Centers
ARRA - Increase Demand for Services (IDS)
Increase services to extend hours to Saturdays from 9am to 2pm in two medical and two dental clinics.  Increase jobs and increase access to uninsured people.
Increased Demand for Services; Creation of new jobs and increase access to medical and dental services for uninsured patients. The goals were to see 2,417 New Patients, 967 Uninsured patients and retain 5.35 FTE jobs.  LMFC provided services to
BROWARD COMMUNITY AND FAMILY HEALTH CENTERS, INC
The purpose of this award is to increase services at existing sites, preserved and create new jobs and help people mostly impacted by the recession such as the uninsured and underinsured populations.  The award will  increase access to primary
Provide additional healthcare/diagnostic/transportation services to patients. Provided these services to approx 464 uninsured new patients last quarter.
The number of unemployed Maui residents has much more than doubled within the past year.  With the current unemployment rate at 7.4 percent up from 2.9 percent in January 2008, more uninsured patients will be accessing services provided by the
The Northeast Missouri Health Council (NMHC) is responding to the need for expanded access to healthcare by utilizing Increased Demand for Services (IDS) Funding to recruit and hire two additional Providers.  NMHC received ARRA-Increased Servic
Increased Demand for Services  The Ho`ola Lahui Hawaii IDS Project consisted of these components:  1) Restore family practice services by hiring an additional 2.0FTE Family Practice Physicians, one of which will be funded through the IDS.    2)
Using funds received through the ARRA Increase Services to Health Centers grant, New Horizon Family Health Services plans to respond to increasing demand for services and increasing chronic disease rates by increasing health center staffing, ex
Homeless Dental Clinics. Increased Demand for Services (IDS) funds were used to provide over 200 evening and Saturday clinics for Homeless adults and children.  A survey of Homeless clients showed almost 70% identified increased dental services
Increased Demand for Services grant to hire an additional physician.
We plan a multi-pronged approach to educating the community about the services available at the CHC. First, we will retain three positions that have been slated for elimination due to budgetary constraints.  Second, we will respond to the incre
HEALTH CARE PARTNERS OF SOUTH CAROLINA, INC.
This grant is funding costs to retain and recruit provider and nursing staff to enable maintenance and expansion of services and hours.
Increased demand for services at health centers: Imperial Beach Community Clinic received an ARRA Increased Demand for Services grant to increase access to primary health care for low-income and uninsured individuals in the city of Imperial Bea
Sonoma Valley Community Health Center developed four IDS initiatives to address the growing number of uninsured in the Sonoma Valley during the economic downturn: 1) recruit and hire a family physician along with a medical assistant to increase
INDIAN HEALTH CENTER OF SANTA CLARA VALLEY
With IDS funding IHC will be able to hire a pediatrician to provide integrated medical care to the increaed number of infants and children that are being seen in the Medical Department. IHC has developed a strong immunization program and has on
Outpatient Medical Center, Inc. acquired IDS Funding in order to add a Case Management component into its list of services.
ARRA- Increase Services to Health Centers
Increased Demand for Services-Community Health Centers
Health Care for Portland's Homeless-Increased Demand for Services
This grant was the Increased Demand for Services (IDS). The designed intent in applying and using these federal funds was for the purpose of assisting with the recruitment, services, staffing, etc. associated with increasing the number of medic
ARRA-Increased Dervices to Health Centers
The American Recovery and Reinvestment Act Increased Demand for Services (IDS) grant supports health centers to meet spikes in uninsured populations through increased supplemental payments.
The IDS project has allowed HopeHealth to hire a full time family practice physician to increase our capacity for seeing new patients from 26 to 56 per week.  HopeHealth receives calls daily from people in need of health services, people who ar
Grant Name: HRSA-Increased Demand for Services (IDS)  Purpose: HRSA awarded Community Healthlink (CHL) this grant to respond to the increasing demand for health care services in our Health Care for the Homeless Program(HCH).  The increased dema
This is a grant to enable successful recruitment of new Jr. Faculty into the recently reorganized cores, Cell Biology and Genetics (CB&G and Communication and Auditory Neuroscience (CAN).
Jr. Faculty Recruitment into New Auditory Neuroscience Cores
This application is a response to RFA-OD-09-005 NIHGMS, Supporting New Faculty Recruitment to Enhance Research Resources through Biomedical Research Core Centers.' The request is for recruitment of a new assistant professor to the Biochemistry
RESPONSE TO RFA-OD-09-005 THROUGH NIHGMS FOR NEW BIOCHEMISTRY FACULTY
The Cardiovascular Center (CVC) at the Medical College of Wisconsin (MCW) is a Biomedical Core Center with ongoing research related to the prevention, detection, treatment and cure of the complex set of cardiovascular diseases related to heart,
New Faculty Recruitment in Stem Cell and Regenerative Cardiovascular Biology
TLR4 Signaling in alcoholic liver disease, Award Number R01AA017729 from the National Institute On Alcohol Abuse And Alcoholism (NIAAA), is aimed at investigating the role of Toll-like receptor 4-dependent signaling in experimental alcoholic li
TLR4 Signaling in alcoholic liver disease
Alzheimer's disease is characterized by the aggregation of 13-amyloid (A13) protein in the brain, widespread neurodegeration, and cognitive decline.  Our work focuses on amelioration of Alzheimer's pathology by reducing or simplifying the major
Chronic sialidase effects on amyloid aggregation and associated pathology
Salmonella enterica serovar Typhi (S. Typhi), the cause of typhoid fever in humans, continues to be a very significant health problem. It is estimated that there are 16,000,000 cases of typhoid fever every year, resulting in 600,000 deaths. Unl
Molecualr Mechanisms of Salmonella Typhi Pathogenicity
threats, such as influenza A, antibiotic-resistant bacteria, and toxin-producing bacteria, such as C. difficile.  Consequently, although this proposal is specifically directed towards B. anthracis, its implications encompass many other urgent
RETROCYCLINS: CYCLIC MINI-DEFENSINS THAT INACTIVATE ANTHRAX TOXINS
This award is to study the mechanism of necroptosis, a novel programmed necrotic cell death pathway, in cancers.
Molecular mechanism of a cellular necrotic cell death pathway
Compelling evidence suggests that alteration of normal prenatal development influences one's lifetime risks for obesity and cardiovascular disorders, which are components of the 'metabolic syndrome. Reflecting the public health importance of e
Adenosinergic mechanism of intrauterine growth retardation
Families with Latino backgrounds now represent the largest ethnic minority group in the United States, and adolescents wtihin the$8 families face substantial challenges to their psychological and behavioral adjustment. Emerging evidence indicat
FAMILY OBLIGATION AND ASSISTANCE AMONG ADOLESCENTS WITH MEXICAN BACKGROUNDS
Autism is a tremendously heterogeneous disorder with complex genetic and neural underpinnings. This grant aims to understand variability in the autism phenotype by examining links between known genetic risk factors for autism and brain structur
NEURAL AND PHENOTYPIC CORRELATES OF AUTISM RISK GENES
We will use fMRl to characterize the neural basis of development in social cogntion. Our understanding of the pathogenesis of psychiatric disorders that affect social cognition and social behavior (e.g., autism, anxiety disorders, anorexia, and
Neuroimaging of th Development of Neural Mechanisms social cognition
We propose to investigate the role of epileptic seizures in oxidative stress. There is a wealth of research that demonstrates epileptic seizures lead to the formation of reactive oxygen species (ROS), which cause oxidative damage to DNA, lipid
Microdialysis Studies of Seizure-Induced Oxidative Stress
The proposed experiments will directly impact public health by developing a novel paradigm to investigate nicotine-induced dopamine release in vivo. These studies will examine the effects of nicotine and the treatment drug rimonabant in the bra
Dopaminergic and Endocannabinoid Interactions in Nicotine Dependence
The proposed study can make more efficient use of cancer genomic data by properly accounting for the clustering structure of gene expressions and selecting predictive cancer biomarkers. It can provide more insights into the genomic mechanisms o
Effective Clustering Penalized Methords for Genomic Biomarker Selection
TITLE: 'MARRIAGE, PHYSIOLOGY, AND HEALTH DURING THE RETIREMENT TRANSITION.'  This longitudinal, observational research project will: 1) Determine whether poor marital functioning predicts greater physiological changes during marital discussions
MARRIAGE, PHYSIOLOGY, AND HEALTH DURING THE RETIREMENT TRANSITION
Ionotropic glutamate receptors (iGluRs) are ligand-gated ion channels that form transmembrane, cation-permeable channels which open upon agonist binding. iGluRs are the major mediators of excitatory synaptic transmission in the central nervous
Mechanism of Allosteric Modulator Action at the Ionotropic Glutamate Receptor
The goal of this project is to develop live attenuated influenza virus vaccine. Influenza is a global infectious viral disease of great public health concern affecting millions of people every year. We plan to create highly attenuated PR8 virus
DEVELOPMENT OF LIVE ATTENUATED INFLUENZA VIRUS VACCINE
Type 1 diabetes (T1D) develops as control of autoreactive CD4 cells is lost, which occurs in part because of escalating responses of cells that escape regulation and are highly pathogenic. While many cell types contribute to this disease, ameli
The tetraspan protein EMP2 is a novel biomarker for endometrial cancer prognosis and survival.  Specificially, EMP2 expression is upregulated in a significant subset of endometrial hyperplasia and cancer patients.  We therefore reasoned that EM
Tumor metastasis represents the major cause of morbidity and mortality in breast cancer.  The studies described here investigate the molecular mechanisms by which biobehavioral factors might facilitate breast cancer metastasis to distant target
SYMPATHETIC NERVOUS SYSTEM REGULATION OF BREAST CANCER METASTASIS
Taste has profound effects on smoking behavior. Most importantly, smokers of flavored cigarette have higher odds for relapse. Gustatory and other visceral sensory information are processed and integrated in the insular cortex. Damaging of insul
Insular cortex and reinstatement of nicotine seeking behavior
The ß-hemoglobinopathies sickle cell disease and ß-thalassemia are among the most common, and most devastating, genetic diseases worldwide. In countries with developed health care systems, care for affected individuals is extremely expensive;
A high-throughput screen for candidate agents that may reverse gamma-globin silen
As the numbers of patients continue to rise after high-dose chemotherapy and/ or irradiation for cancer and other diseases, more attention is focused on improving their quality-of-life, with fertility one of the top priorities for young people.
Experimental engineering of ovarian grafting to promote angiogenesis for fertility preservation
Center for Reproductive Medicine & Infertility
CHILDREN'S HOSPITAL & RESEARCH CENTER AT OAKLAND
Statins are widely used to reduce cardiovascular disease risk by lowering LDL cholesterol (C), but the magnitude of this effect varies widely among individuals. The overall objective of this proposal is to provide evidence in support of a novel
HMG-CoA reductase alternative splicing and LDL response to statin
Despite the growing number of evidence-based mental health treatments for youth being developed, few are effectively practiced routinely in community settings. One reason may be the lack of attention paid to how these treatments are implemented
IMPLEMENTATION STRATEGY FOR DELIVERING A SCHOOL-BASED MENTAL HEALTH PROGRAM
This R21 proposal will explore whether abnormal white matter anatomical connections may underlie the gray matter (functional) abnormalities previously seen in fMRI data from subjects with bipolar disorder. We will collect, in the same subject,
TRACTOGRAPHY, WHITE MATTER INTEGRITY AND FMRI IN BIPOLAR DISORDER
MEMORY, THIAMINE LEVELS AND BRAIN STRUCTURE IN HEART FAILURE Many heart failure (HF) patients have short-term memory deficits, which can adversely impact management of their disease and dramatically increase morbidity and mortality. Injury in b
MEMORY, THIAMINE LEVELS AND BRAIN STRUCTURE IN HEART FAILURE
Creation of 100-200 micron dimension probes with multiple electrode sites from silicon wafers for the monitoring of glutamate and dopamine simultaneously in the brains of live, laboratory rodents
A MICROMACHINED, MULTIELECTRODE MICROPROBE FOR MONITORING GLUTAMATE AND DOPAMINE
The study will explore the mechanisms within social networks, including social learning variables (including the presence of models of behavior, social support, self efficacy to control drinking, and others), acculturation, and ecological varia
ARRA: Understanding Networking and Alcohol Consumption Among Recent Immigrants
The purpose of this project is to develop and test brief communications of nutrition facts and alcohol contents that a)individuals can effectively use to monitor their consumption, b)can motivate them to drink moderately, and c)could be require
ARRA: Disclosing Contents of Drinks: Experimental Test on Natural Consumption Behavior
Mechanisms of Ethanol-Induced Neuroinflammation and Neurodegeneration;     The application addresses broad Challenge Area:  (01) Behavior, Behavioral Change, and Prevention and specific Challenge Topic:  01-AA-102: Functional Roles of Neuroimmu
Mechanisms of Ethanol-Induced Neuroinflammation and Neurodegeneration
A SonoKnife for Advanced Cancers.  Development of a new technology  for non-invasive thermal ablation of superficial head and neck tumors or positive lymph nodes, namely, a SonoKnife, a scanned, line-focused ultrasound thermal therapy system (t
The Assessment of Local Environmental Risk Training (ALERT) to Reduce Health Disparities responds to the need for building the capacity of community based organizations (CBOs) to actively participate as equal partners in research projects and t
ASSESSMENT OF LOCAL ENVIRONMENTAL RISK TRAINING (ALERT)
bilayers that are attached to a solid surface. They are inherently non-dynamic, as proteins they contain are generally immobile by nature, and an attached bilayer is not deformable. The proposed research is organized into a series of specific
Suspended Bilayers: new technology to study the Dynamics of Membrance structure and function
TITLE: 'USING PERCEPTUAL AND ADAPTIVE LEARNING TO ADVANCE CHEMISTRY EDUCATION.'  Recently developed innovations in perceptual and adaptive learning technologies will be applied to chemistry learning in community college settings and rigorously
USING PERCEPTUAL AND ADAPTIVE LEARNING TO ADVANCE CHEMISTRY EDUCATION
We described rickets in children in our inner city area (over 80% minorities) with either low or normal circulating 25-hydroxyvitamin D (25-OHD) levels, and have found that vitamin D deficiency (circulating 25-OHD less than 20 ng/ml) occurs in
Classical and Non-Classical Responses to Vitamin D in children: The Role of DBP Genotype
Title: Self-monitoring using GPS- and accelerometer-equipped smartphones  Description: We are evaluating the validity and reliability of self-monitoring diet, stress, and exercise (three key risk factors for cardiovascular disease) using a mobi
SELF-MONITORING USING GPS- AND ACCELEROMETER-EQUIPPED SMARTPHONES
Title:ANTIBODIES TO DEFINE MOLECULAR MECHANISMS OF HYPERTRIGLYCERIDEMIA  DESCRIPTION: This application addresses Challenge Area (06): Enabling Technologies and Specific Challenge Topic 06- HL-102, which is to develop high affinity/high specific
ANTIBODIES TO DEFINE MOLECULAR MECHANISMS OF HYPERTRIGLYCERIDEMIA
Schizophrenia is defined by a lack of a straightforward genetic cause for a very large majority of affected individuals. The prefrontal cortex (PFC), among other brain regions, is thought to be frequently in subjects in schizophrenia, as reflec
Epigenetic Markings in Developing and Diseased Prefrontal Neurons
This application addresses the broad Challenge Area (03) Biomarker Discovery and Validation and specific Challenge topic, 03-MH-101: Biomarkers in Mental Disorders and is entitled: Biomarkers of Suicide Risk in Adolescents and Young Adults: Fac
Biomarkers of suicide risk in adolescents and young adults: factors that contirbute to hight risk in biopolar disorder
This project is entitled Biomarkers for Outcomes in Late-Life Depression (BOLD).   This project examines a biomarker-guided treatment for late-life depression which could improve outcomes by rapidly identifying an effective medication for each
BIOMARKERS FOR OUTCOMES IN LATE-LIFE DEPRESSION (BOLD)
Bariatric surgery remains the most effective treatment for morbid obesity.  In addition, bariatric surgery such as Roux-en Y Gastric Bypass (RYGB) causes the immediate resolution of type-II diabetes in the majority of patients (84%).  This rema
Understanding the role of bile as a mechanism for improved glucose homeostatsis following bariatric surgery
The guiding question is whether early intervention can improve long term outcomes for psychotic disorders in the U.S. We hypothesize that a specialized multi-component intervention, delivered in a public mental health clinic will be more effect
Specialized teartment early in Psychosis (STEP): A community helath center based cost effectiveness study
Predicting Chemotherapy Induced Mucositis with Genetic and Clinical Factors. The broad long term objective is to use genotypic and clinical characteristics to improve individualized healthcare. Severe mucositis is a dose limiting toxicity of hi
Predicting Chemotherapy-Induced Mucositis with Genetic and Clinical Factors
The goal of this program is to provide scholarships to disadvantaged students which will allow them to attend Indiana University and specialize in a degree program.
ARRA - Scholarships to Disadvantaged Students
ARRA-Scholarships for Disadvantaged Students. It is the goal of Tennessee State Unviversity help eliminate the nursing shortage.
Scholarships for Disadvantaged Students (SDS) for Medical, Dental, Pharmacy and Baccalaureate Nursing students.
Increase Services to Health Centers to support the addition of clinical providers and support personnel in order to provide care to 3,000 new users.
Morris Heights Health Center - Expansion of Primary Care Access
Through this IDS project, Delaware Valley Community Heath (DVCH)  will first recruit a mid-level provider and pediatrician for Maria de los Santos Health Center (MDLS). This relocated center was opened in 2008 and has physical capacity for more
The long-term objective of this Program Project is to perform a systematic analysis of the cellular and molecular mechanisms regulating thymic epithelial cell (TEC) homeostasis and the role of TECs in the involution of the adult thymus. The thy
Mechanisms Controlling Thymic, Homeostasis, Involution, and Rebound
The fundamental roles of innate and adaptive host responses are to recognize and eradicate invading antigens, pathogens or altered self components with the purpose of restoring tissue integrity and homeostasis.  While resolution can occur when
The Mayo Clinic Center for the Individual Treatment of Alcohol Dependence (CITA) is a P20 exploratory/ developmental alcohol research center proposal with the over-arching theme of using translational research strategies to create a new researc
The Mayo Clinic Center for Individualized Treatment of Alcohol Dependence
Hopkins Center for Population Aging and Health: An emerging consensus calls for the development of new interdisciplinary research within public health that integrates divergent perspectives, frameworks and methods. The HCPAH will be an interdis
HOPKINS CENTER FOR POPULATION AGING AND HEALTH
The mission of the Northwest Roybal Center (NRC) is to improve the health, well being, quality of life and productivity of older adults with cognitive impairment, midlife and older adults at risk for cognitive impairment, and their caregivers t
NRC: Improving Healthcare for Cognitively Impaired Elders and Their Caregivers
Early Stage Investigator Recruitment in Cancer Research  This proposal was submitted to fund the recruitment of a basic scientist who would be incorporated into the translational science programs of the UNC-Lineberger Comprehensive Cancer Cente
Early Stage Investigator Recruitment in Cancer Research
DESCRIPTION (provided by applicant): This application is in response to RFA-OD-09-005, title 'Recovery act limited competition: Supporting new faculty recruitment to enhance research resources through biomedical research core centers (P30). The
Faculty Recruitment into Neurobiology of Addiction Research Center (NARC)
The aim of this ARRA proposal for NIDCD P30-supported new faculty recruitment at the University of Wisconsin (UW) - Madison is to foster the development of a leader in the field of voice and swallow neuroscience research. We will develop the ca
ARRA Voice and Swallow Neuroscience Research Core
Although cochlear implants (CI) can dramatically improve speech recognition for many patients in quiet surroundings, CI performance and outcome is variable across individuals; speech recognition in noise is often worse, and music perception is
Development of Translational Research to Improve Outcomes for Cochlear Implants
The Marine Biological Laboratory (MBL) in Woods Hole, Massachusetts, proposes to launch a high-impact, multidisciplinary and unique initiative in regenerative and stem cell biology drawing upon the special advantages of marine invertebrates. Re
The objective of this proposal is to recruit two tenure track Assistant Professor RNA biologists, one who specializes in bioinformatics and one who specializes in genomic approaches to the study of non-coding RNAs, to join and complement the fa
Enhancement of RNA Related Research at Case Western Reserve University
The mission of the Tulane Hypertension and Renal Center of Excellence (THRCE) is to stimulate research activities related to cardiovascular, kidney, and hypertension related diseases and is a multidisciplinary Center with members from clinical
NEW FACULTY RECRUITMENT TO ENHANCE RESOURCES IN HYPERTENSION RESEARCH
DESCRIPTION (provided by applicant): This is an application in response to RFA-Recovery Act Limited Competition: Supporting New Faculty Recruitment to Enhance Research Resources through Biomedical Research (P30) ~ to provide support for recruit
Stanford Mood Disorders Center: Enhancing Core Clinical Research Resources
This grant proposal is in response to RFA-OD-09-005, 'Recovery Act limited Competition: Supporting New Faculty Recruitment to Enhance Research Resources through Biomedical Research Core Centers' and is entitled 'Translational Neuroscientist and
TRANSLATIONAL NEUROSCIENTIST AND THE HOPE CENTER
Transcription factors are key regulators of several aspects of organogenesis, and in the heart, several important DNA-binding transcription factors are powerful regulators of cardiac cell fate and organogenesis. Less well studied are the roles
IROQUOIS HOMEOBOX TRANSCRIPTION FACTORS IN HEART DEVELOPMENT AND PHYSIOLOGY
Significant effort has been committed to developing efficacious alcohol interventions for college students, while little attention has been paid to the needs of the majority of high school seniors who transition to work rather than a four-year
BRIEF ALCOHOL INTERVENTION FOR SCHOOL-TO-WORK TRANSITIONS
The purpose of the study is to evaluate the effectiveness of the Oxford House model with Latino residents whose values, beliefs and behaviors differ depending on their level of acculturation. In the past, those Latino individuals who have used
Evaluating a Bilingual Vultnary Community Based Healthcare System
This project's long-term goal is to enhance the effectiveness of AUD relapse prevention interventions through advancing understanding of the relationships among interpersonal stress, affect regulation, alcohol lapse, and patterns of alcohol use
RELATIONSHIPS AMONG INTERPERSONAL STRESS, AFFECT REGULATION, AND ALCOHOL LAPSE
This project seeks to determine the mechanisms whereby ingestion of ethanol by dams increases the concentration of atRA (all-trans-retinoic acid) in vivo in embryo hippocampus during normal vitamin A (retinol) nutriture. We developed a LC/MS/MS
Long-temn alcohol consumption progressively leads to multiple immune defects. Chronic alcoholics display lesions in both innate and adaptive immunity, and experience increased rates of bacterial and viral infection. Of particular interest, exte
Chronic ethanol, B cell competence and lymphoid integrity
Diabetes mellitus (DM) is a prevalent, costly condition with high morbidity and mortality. Our goal is to determine prospectively mechanisms by which type 2 DM alters cerebral microcirculation and contributes to brain tissue damage and cognitiv
CEREBROMICROVASCULAR DISEASE IN ELDERLY WITH DIABETES
Alzheimer disease (AD) imposes a substantial societal burden. Clinical AD likely results through the interaction of 3 factors: reserve, AD- and vascular pathology. Brain MRI and cognitive tests can identify proxy measures of reserve and subclin
Neurotrophic Factors: Genetic Variation and Serum Levels in Brain Aging
The study is to determine whether African American with mild AD can be enrolled and retained in a six month aerobic exercise training in order to examine the effect of aerobic exercise training on neurocognitive functions and on celebral glucos
Effects of Standardized Aerobic Exercise Training on Neurocognitive and Neurodegeneration
Health or disability - General/Unspecified
This proposal’s primary objective is to (develop intervention and assessment) strategies that nursing homes (NHs) can use to improve how their staff members provide choice to residents about important activities of daily living. Providing cho
Providing Choice to Nursing Home Residents:  A Quality of Life Intervention
UNIVERSITY OF TEXAS MEDICAL BRANCH AT GALVESTON
Starting in the 1990's, some physicians began to devote all of their time to the care of hospitalized patients. They are referred to as hospitalists. Our preliminary data suggest a rapid growth in the number of hospitalized older patients cared
CARE OF THE ELDER HOSPITALIZED PATIENT:  THE ROLE OF HOSPITALISTS
Control of Lymphocyte Homeostasis by Foxo Transcription Factors: Hematopoietic cells constantly turn over. Their rates of division and death determine the steady-state number of cells and size of lymphoid organs. In particular, T lymphocytes ar
CONTROL OF LYMPHOCYTE HOMEOSTASIS BY FOXO TRANSCRIPTION FACTORS
The long-term goal of this project is to generate a detailed understanding of viral meningitis in realtime. Knowledge derived from these studies are expected to foster the development of novel interventions to treat this potentially fatal disor
Immune Cell Dynamics During Central Nervous System Viral Infection
Tuberculosis (TB) is a severe global health threat and the emergence of multiple drug resistant Mycobacterium tuberculosis (Mtb) strains elevates the threat to a truly alarming state.  One third of the world is latently infected with Mtb and th
MECHANISM OF MYCOBACTERIUM TUBERCULOSIS PERSISTENCE
ABSTRACTIron is essential for virtually all forms of life and plays a central role in cellular metabolism. Microbes have developed complex strategies for the acquisition, storage, trafficking, utilization and detoxification of iron.  One of the
IRON HOMEOSTASIS IN SALMONELLA-HOST INTERACTIONS
Candida is among the most common causes of nosocomial infections in the United States and worldwide. Even with antifungal therapy, disseminated candidiasis causes an unacceptable 40%-50% mortality. Furthermore, resistance to antifungal therapi
INNATE EFFECTORS OF RALS3P-N ANTI-CANDIDA VACCINE
BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE
C57BL/6 (B6) mice are genetically resistant to fatal HSV encephalitis (HSE) compared to 129S6 (129) and BALB/c that are susceptible. We have shown that fatal HSE in 129 mice results from hyper-inflammatory responses involving macrophages and ne
MECHANISMS OF IVIG PROTECTION IN VIRAL ENCEPHALITIS
. Aim 1 uses in vitro approaches to prove that P2Y12/CysLT3R is a true LTE4-reactive receptor. Aim 2 seeks to prove that P2Y12/CysLT3R accounts for the striking proinflammatory effects of LTE4 in the lung in vivo, and to identify the essential
Regulation of Pulmonary Prostaglandins by Leukotriene E4
HIV-1 Replication and Pathogenesis in vivo - ARRA The goals of this project are to define how HIV-1 interacts with pDC and to elucidate the role of pDC cells in HIV-1 replication and pathogenesis. As the major sensor of viral infections, altere
HIV-1 Replication and Pathogenesis in vivo - ARRA
Traditional viral vaccines are normally developed by either creating attenuated viral strains for inoculation, such as the Sabine strain of poliovirus, or by injecting the patients with purified viral proteins such as employed in the hepatitis
M. tuberculosis infection is an ongoing global health crisis that requires new drugs or vaccines for effective control. Although many individual genes have been shown to be important for M. tuberculosis pathogenesis in the mouse, we still under
MOLECULAR ANALYSIS OF THE RIP1 VIRULENCE PATHWAY OF M. TUBERCULOSIS
Effective control of systemic autoimmune diseases such as rheumatoid arthritis (RA) currently relies on the use of intense generalized immunosuppression, thus increasing the risk of infection and malignancy. A better theoretical approach to the
Epigenetic Control of T cell Autoimmunity
This project is to investigate the mechanism of activation of the interferon regulatory factor (particularly IRF-3) following virus infection.  The activation of IRFs, which is triggered by the phosphorylation of certain Ser/Thr residues, resu
THE MECHANISM OF INTERFERON REGULATORY FACTOR (IRF) ACTIVATION
Antibiotic resistance is a looming global problem threatening some of the most significant public health gains of the past century. This critical health challenge, together with the emerging threat of biowarfare agents calls for the identificat
TARGETING TYPE II SECRETION, A COMMON VIRULENCE PATHWAY
Our goal for this 2 year award is to define in detail the therapeutic potential of recently identified tolerogenic DC populations in graft versus host disease (GVHD). We have recently identified CCR9- expressing plasmacytoid DCs as an extremely
Tolerogenic DC as Therapeutic Agents in GVHD
The use of Bacillus anthracis as a bioweapon depends on dispersal of its spores in the environment, entrance into the body, spore uptake by the human host cells, germination of the spores in the host and the pathological consequences of the hos
IMMUNOBIOLOGY OF BACILLUS ANTHRACIS SPORE-HOST INTERACTIONS
Bacterial infections constitute one of the major health problems worldwide. A gradual increase in the resistance to antibiotics leads to a serious thread for successful treatment of bacterial infections. This feature has stimulated the interest
(ARRA) Development of a novel strategy to produce antibacterial glycoconjugate vaccines
Resistance to infection is determined by immune system activity and the overall physiological condition of the host. This project will determine how the seemingly disparate physiological processes of immunity, metabolism and reproduction are ge
GENETIC NETWORK LINKING IMMUNITY TO ENERGETIC STRESS, METABOLISM AND REPRODUCTION
This project will characterize and develop the ability to transcriptionally modulate HIV-l latency. We have recently discovered that antisense non-coding RNAs can regulate gene transcription and evidence suggests that HIV-l also utilizes this m
Non-Coding RNAS Involved in HIV-1 Latency
Major developments in molecular biology, coupled with strides in genomics and proteomics, have led to an explosive growth in biological data. To obtain usable, relevant information from these vast databases (e.g. through data mining) it is mand
ARRA: Integration of Clinical, Genomic and Proteomic Data using a Bioinformatic Approach
As a major reason of osteoporotic and age-related fractures, deterioration of bone quality is reflected mainly in the reduced toughness. Recent evidence has evinced that bone may experience two distinct stages in the post-yield deformation: beg
The robust regeneration potential of fetal tissue suggests that developmental biology may help guide strategies for tissue regeneration in adults. Decreases in regenerative capacity post-utero and with increasing age are likely due to multiple
ARRA: ENGINEERED DELIVERY OF ADULT VERSUS FETAL STEM CELLS FOR BONE REGENERATION
The U.S. Department of Health & Human Services and the National Recreation & Park Association both recommend Yoga as a form of total-solution exercise for older adults, capable of providing cardiovascular fitness, resistance training for muscle
Safe & Effective Yoga Prescription for Older Adults: Biomechanical Considerations
The increase in T cell numbers associated with Sezary Syndrome likely occurs as a result of hyperproliferation as well as decreased apoptosis. The mechanisms involved resulting in these effects however are not clearly understood. We have previo
Dual Role of IL-16 in Dysregulated Growth of CTCL Cells
Cyclooxygenase (COX) inhibitors lower the risk of colorectal cancer (CRC) and inhibit tumor growth in animal and cell culture models. However, their efficacy in treating existing CRC remains controversial. Previous research in our laboratory ha
TARGETING COX-2 EXPRESSING MYOFRIBROBLASTS IN COLORECTAL CANCER (CRC)
Melanoma differentiation associated gene-7/interleukin-24 (mda-7/IL-24) is a pleotrophic tumor suppressor molecule that exhibits the unique property of inducing apoptosis only in cancer cells. Dietary monoterpenes, such as perillyl alcohol (POH
Pancreatic Cancer Management by Novel Gene Therapy & Dietary Agents
Our long-term objectives are 1) to develop appropriate molecular probes for in vivo multimodality imaging of tumor angiogenesis, growth, and metastasis and 2) to use molecular imaging techniques to predict and monitor treatment efficacy. The in
While understanding the trade-off between tumor control probability and normal tissue complication probability lies at the heart of radiotherapy treatment planning, the reporting of the dependence of complications on dose distributions is curre
ATLASES TO REPORT AND CORRELATE RADIOTHERAPY DOSE DISTRIBUTIONS WITH OUTCOMES
The breast cancer susceptibility gene 1 (Brca1) plays a key role in both hereditary and sporadic mammary tumorigenesis. However, the extent to which BRCA1-activated molecular pathways contribute to its tumor suppressor activity also remains unc
ROLE OF BRCA1/AKT1 PATHWAY IN THE TUMORIGENESIS
Studies in this proposal will help to understand how stem cells are maintained in the adult mammalian organism and whether abnormalities with stem cells are responsible for cancer. Knowledge obtained during this study will help to develop new t
Cell Polarity in Self-renewal and Differentiation of Stem/Progenitor Cells
'Overall Purpose To determine whether the Tg11.5kb-GFP mouse is a suitable model for analyses of adult stem cell activity, and if so, how best can this mouse model be used to demonstrate specific properties, functions and potential utilizations
Normal and Cancer Stem Cells of the Mammary Gladn
The overall goal of this application is to discover and validate multiple novel plasma protein biomarkers of human ovarian cancer. We will initially discover a substantial number of candidate biomarkers through parallel analysis of two compleme
Identification of ovarian cancer plasma biomarkers
Genetic alterations and epigenetic modifications are hallmarks of cancers, including prostate cancer (PCa). Understanding factors associated with the progression of PCa will have a significant impact on management and treatment of the disease.
Global genetic and epigenetic approaches to progression of Pca
HDAC inhibitors (HDACI) are promising anti-tumor agents that have just entered the clinics. Despite their potent activity, the fundamental question of how HDAC inhibitors achieve their anti-tumor effects remains poorly understood. It is not kno
HDAC10, MITOCHONDRIA & AUTOPHAGY-A NOVEL NETWORK TARGETED BY HDAC
TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION
Previous studies revealed that certain integrins expressed on endothelial cells play a significant role in the progression of angiogenesis and are an attractive target for the development of angiostatic drugs that may have an application in the
Interaction of thrombospondin-1with alpha9beta1 integrin in glioma angiogenesis
Targeting tumor vessels has become a mainstream mode of treatment for a variety of malignancies. In addition to anti-angiogenic therapy, vascular disrupting agents (VDAs) are a new group of compounds that selectively kill tumor endothelial cell
Development of Vascular Disrupting Agents
In collaboration with the structural biologist Dr. Hao Wu, we solved the co-crystal structure of one of the compounds in complex with caspase-7. The crystal structure revealed the allosteric nature of the binding and also provides guidance for
IDENTIFICATION OF INHIBITORY COMPOUNDS FOR APAF-1 BY HIGH THROUGHPUT SCREENING
This proposal seeks to develop and apply a new strategy of cancer therapy through the use of aptamers against target proteins and cells. It focuses on the Basal-like Breast Carcinoma (BLBC), which is a particularly aggressive subtype of breast
ARRA Funded:  Target Validation and Drug Development with Aptamers for Basal-like Breast Cancer
Juvenile Polyposis (JP) is an autosomal dominant syndrome predisposing to the development of hamartomatous polyps of the colon, rectum, and stomach. Affected patients have an approximately 50% risk of developing gastrointestinal cancer. Work in
Regulation of SMAD4 and BMPR1A Expression in Juvenile Polyposis
Non-small cell lung cancer (NSCLC) is a leading cause of cancer-related death. Novel therapeutic strategies are urgently needed. With this proposal, we are planning to move toward this goal by gaining a better understanding of the molecular net
Characterization and Drug Targeting of PML Tumor Suppressor in Lung Cancer - ARRA Stimulus Funding
The long-term goal of this research is to help develop improved chemopreventive interventions for colorectal cancer based on molecular targeting of crucial events in colorectal tumorigenesis. Inflammation contributes to colon carcinogenesis. Pr
15-LOX-1 EFFECTS ON COLITIS AND COLON CANCER
Natural products show outstanding potential as starting point in drug discovery, especially in the quest for anticancer drugs.  The research proposed here will explore structure-activity relationships of largazole, a marine natural product that
The overall goal of this proposal is to develop a novel local drug delivery system for cancer radiotherapy by direct intratumoral administration of a thermally sensitive macromolecule conjugated to a therapeutic radionuclide of interest. Therma
LOCAL RADIONUCLIDE DELIVERY TO SOLID TUMORS BY INJECTIBLE BIOPOLYMER
DESCRIPTION (provided by applicant): For over half a century, androgen deprivation therapy (ADT) has been known to have beneficial effects on prostate cancer due to the testosterone dependence of prostate tumor cells, yet its optimal use still
Optimizing use of androgen deprivation therapy for prostate cancer
Mucus Penetrating Nanoparticles for Early Stage Cervical Cancer: Drugs administered systemically typically reach the cervicovaginal (CV) tract in very low concentrations. As a result, drug therapies for diseases that affect the CV tract typical
MUCUS PENETRATING NANOPARTICLES FOR EARLY STAGE CERVICAL CANCER
With approximately 9 million Americans passing through correctional institutions annually and an average daily population of over 2 million, there are multiple opportunities to address the smoking cessation needs of this high risk and underserv
Sustaining Tobacco Abstinence after Incarceration
Individuals diagnosed with Attention Deficit Hyperactivity Disorder (ADHD) smoke more than the general population, initiate use at a younger age, and in general report more difficulty trying to quit. Several converging lines of work suggest tha
SMOKING REINFORCEMENT IN ADULTS WITH & WITHOUT ADHD
The normal auditory system possesses exquisitely well-adapted processes for extracting behaviorally relevant acoustic signals from the environment, especially under challenging listening conditions such as in the presence of competing signals o
Stroke is the leading cause of serious long-term disability in the United States. Adults who have strokes in the  right side of the brain often 'miss the point' of what they hear, read, or see -- a life-altering problem that can have devastatin
Treatment for Language Processing Deficits in Adults with Right Brain Damage
'Development of a laser holography otoscope for diagnosis in the clinic'  Conductive hearing loss, usually associated with middle-ear disorders, is the most common reason for otologic surgery. The pathogenesis of conductive loss includes, among
ARRA-Development of a Laser Holography Otoscope for Diagnosis in the Clinic
The developing mouse tooth has long been used as a powerful model system for studying the molecular mechanisms regulating organ development and the pathogenic mechanisms of tooth developmental anomalies in humans. Tissue recombination studies a
MOLECULAR PATTERNING OF MAMMALIAN DENTITION
Bone marrow mesenchymal stem cells (BMMSCs) are multipotent stem cells capable of differentiating into different lineage cells including osteoblasts, chondrocytes, adipocytes, cardiomyocytes, myoblasts, and neural cells. A recent major breakthr
Interplays between the Jaw Mesenchymal Stem Cells and T Lymphocites
Amelogenesis imperfecta (AI) is a group of diverse inherited disorders most often considered as a single trait and not often associated with syndromes or metabolic disorders. However, there have been documented case reports in which AI has been
Molecular Mechanisms for Extracellular PH Control during Amelogenesis
The objective of the Health Professions Programs as supported through ARRA is to address health professions workforce shortages.  Programs funded promote training in nursing and public health, help educational institutions, and increase the div
HEALTH AND HOSPITALS, LOUISIANA DEPARTMENT OF
Highway improvements Route 9 Lisbon and Sabattus
Provide Preliminary Planning and Professional Engineering services for assisting the US Fish and Wildlife Service (USFWS) in awarding a Design Build Contract, for the relocation of the 25kV transmission line across the tidal marshlands within t
Replace Lowry Ave Over Mississippi River Including Approaches and Stormwater Quality Improvements
St Croix Valley RR Bridge over the Snake River in Pine City
This award provides for ARRA Cost of Living Adjustment (COLA) and Quality Improvement (QI) Funding for Head Start.  Head Start promotes the school readiness of low-income children through the provision of comprhensive health, developmental and
ARRA COLA and Quality Funds will be used to  a)  Provide Portland State University 18 credit ECE/Infant-Toddler Certificate program to EHS Home Visitors to improve staff qualifications;  b)  Provide Creative Curriculum Intensive training to EHS
AARA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act. Head Start promotes the school readiness of low-income children through the provision of comprehen
Highway Infrastructure Investment Grant: Urbanized Areas over 200K Population and Available for Use in Any Area (Flexible)
Bridge Replacement over Federal Spring Branch
This project between the U.S. Fish and Wildlife Service and The Nature Conservancy benefits the public by restoring habitat for many wildlife species dependant on mature forest stands for survival.  This endeavor is a continuation of an ongoing
Highway Infrastructure Investment - Bridge rehabilitation, no added capacity (no added travel lanes) - From funding for use in any Area (flexible) - This represents Nebraska's share (40%) of this two-state project; the State of Missouri's share
Highway US-136, Missouri River Bridge, Brownville Bridge
President Obama signed the ARRA stimulus act and the Lusk Housing Authority was awarded $42,381. We put bids out for new steel siding on some of our rental units and the work is already complete.
Lusk Housing Authority New siding project
The purpose of this contract is to obligate $179,423.50 for General Grant National Memorial, Complete Rehabilitation of General Grant's Tomb and Overlook Pavilion.                     Design and Contruction of New Electrical Service to the Over
Shenandoah Road Rehabilitation Phase 1 repair road at various parking areas.  Work consisted of asphalt repair and overlay.
This contract is to repair and rehabilitate comfort stations and picnic/camp areas for the Great Smoky Mountains National Park in Tennessee and North Carolina.
Work planned for this award will restore and enhance 178 acres of native grassland habitat on the landsite of the Chihuahuan Desert Nature Center.  The project will provide native grassland habitat for migratory and resident wildlife species fo
Private Lands Agreement:  Chihuahuan Desert Research Institute Grassland Restoration
COASTAL PRAIRIES COALITION, GRAZING LANDS CONSERVA
Prairie Enhancement for Prairie Chicken Habitat
To provide technical and financial assistance to identify, protect, conserve, manage, enhance or restore habitat or species on private lands.
Invasive Species Control in Desert Grasslands and Cienegas
US-160; US-89 to Van's Trading Post w/o TUBA CITY
Environmental improvements, stormwater drainage in Maine Mall area
BAY STREET REHABILITATION, PART 2, CITY OF GLENS FALLS
ZIM SMITH TRAIL PART 2, BIKE/PED TRAIL CONSTR, SARA COUNTY
TEP: DAY PECKINGPAUGH CANAL MOTORSHIP MUSEUM
1R - CR108 (DUNNING ST) RESURFACING PROJECT, SARA COUNTY
1R - CR28 (ELM AVE) RESURFACING PROJECT, GREENE COUNTY
FAS 1784, County Highway 5 (Shattuc Rd.)
East Lake Sammamish Parkway-NE Inglewood Hill Road to NE 28th Place
The Screen Machine Scalper 77C portable Screening Plant
Electronic health records are expected to impact health care disparities by allowing better tracking of individuals with chronic conditions in order to provide timely, effective and appropriate interventions. Clinic operations will also benefit
The awarding of the ARRA CIP grant allows the Southern Region Community Health Center (SRCHC) to expand an additional 19,638 sq. ft. by adding  8,674 sq. ft. on the first floor, 10,125 sq. ft. on the second floor, and an 839 sq. ft. building to
Grant Name: Captial Improvment Program, New Facility Project  Caring Health Center, Inc, (CHC) is an integral part of the community health care system in greater Springfield (Massachusetts) with a proven history of addressing issues that affect
CIP ? The Construction Improvement Project (CIP) grant for CAPWN Health Center is a Construction Project.  The Construction project will add 1,729 square feet of space to the existing CAPWN Health Center main clinic in Gering, Nebraska.  The ex
Tuberculosis (TB) is an infectious disease of global importance; in 2006, there were more than 9 million incident cases and 1.7 million deaths attributable to TB. The emergence of multidrug-resistant (MDR) and extensively drug-resistant (XDR) T
Prevalence, risk factors and consequences of complex M. Tuberculosis infections
The Retinoblastoma (RB) protein is a critical regulator of cell cycle progression, senescence, and differentiation. Our long-term goal is to better understand the cellular mechanisms controlling RB function in mammalian cells, focusing on the m
The Identification and characterization of the methylation of Retinablastoma
A molecular dynamics study of Amyloid beta peptide structure near lipid bilayers. Alzheimer?s disease is quickly becoming a major cause of death throughout the world, especially among the elderly population in developed nations.  Thus, it is im
A molecular dynamics study of Amyloid beta peptide structure near lipid bilayers
Estradiol has been shown to enhance basal forebrain cholinergic function and cognitive performance, but the mechanism by which estradiol exerts these effects is unknown. GPR30 is a novel estrogen receptor that is expressed in the brain and othe
Role of GPR30 in Mediating Estrogen Effects on Neurons and Cognitive Performance
As people get older, they confront a variety of negative life events, including physical and mental changes and the loss of social relationships. In spite of these changes, many older adults maintain relatively high subjective well-being, raisi
Self-compassion and Well-being in the Elderly
The primary objective of this project is to investigate the molecular mechanisms that underlie a genetically defined, natural transplantation reaction that occurs in the primitive chordate, Botryllus schlosseri. We have recently published the c
MOLECULAR AND CELLULAR BIOLOGY OF AN ANCIENTALLORECOGNITION SYSTEM
The 1918-20 influenza pandemic was the largest, most lethal epidemic in modern: history. It spread over the entire world in about six months and killed between 20 and 100 million people. Yet, despite such a devastating event, there is little de
The Effect of the 1918 Influenza Pandemic on Seasonal Influenza in the U.S.
MEDICAL COLLEGE OF GEORGIA RESEARCH INSTITUTE INC
The overall goal of this project involves the establishment and analysis of a new autoimmune(AI) mouse model where T cells that are self-reactive escape deletion due to a defect in the presentation of tissue specific antigens (TSAs) in the thym
DYNAMIC TRACKING OF AUTOREACTIVE AND FOXP3+ REGULATORY T CELLS IN AIRE-/- MICE.
Gastric carcinoma is the second most common cause of cancer related deaths worldwide. Helicobacter pylori (H. pylori) has been identified as a major causative agent in gastric cancer. H. pylori infection is common worldwide, acquired during chi
H. PYLORI INFECTION AND MANIPULATION OF THE HOST INFLAMMATORY RESPONSE
There is now growing evidence that livestock may be involved in spread of community-associated Methicillin Resistant Staphylococcus aureus (CA-MRSA) recent studies from Europe and Canada report a new strain (ST 398) that maybe associated with p
Prevalence of Community-Acquired MRSA in Live Pigs and their Handlers
DESCRIPTION (provided by applicant): Many signaling cascades have been implicated in hematopoietic development. Among these is the wnt pathway, which has been proposed to be involved in the self-renewal of hematopoietic stem cells (HSCs) and in
Influenza virus is a seasonal pathogen with the potential to cause pandemic infection; it results in respiratory disease ranging from subclinical symptoms to life-threatening primary viral pneumonia. Despite the availability of a yearly vaccine
MICRORNA BIOLOGY AND THE HOST RESPONSE TO INFLUENZA VIRUS INFECTION
Agent-based modeling of virus-host cell interaction in salivary gland disease:  A computational model utilizing agent-based modeling will model the replication and assembly of the BK virus (BKV) within a salivary gland cell. BKV has recently be
Agent-based modeling of virus-host cell interaction in salivary gland disease
Free-Living Protozoa Promote Survival of Vibrio Parahaemolyticus - ARRA Stimulus Funding
Between 2001-2003 there were 11.6 million annual ambulatory care visits for skin and soft tissue infections, with a 31% increase in emergency department visits compared to the previous decade, according to the National Hospital AmbulatoryMedica
BEDSIDE EMERGENCY ULTRASOUND FOR THE EVALUATION OF SOFT TISSUE INFECTIONS
Technical Summary  The broad, long-term objective of this proposal is to test the overall hypothesis that Neutrophil Extracellular traps (NETs) contain posttranslationally modified self-antigens, and that the resultant, normally cryptic epitope
PROFILING EPIGENETIC BIOMARKERS FOR THE STUDY ANDTREATMENT OF LUPUS
DESCRIPTION (provided by applicant): Many bacteria regulate virulence factor expression as a function of their population density. This phenomenon, known as 'quorum sensing' (QS), is driven by the detection of a variety of small molecules, coll
ARRA Eukaryotic Translation of Prokaryotic Quorum Signals
Malaria is an infectious disease caused by Plasmodium falciparum, a protozoan parasite. In 2002, an estimated 2.2 million people were exposed to the threat of malaria with an estimate of 515 million clinical attacks, resulting in over a million
A RAPIC SYNTHESIS OF ANTIMALARIAL ARTEMISININ
DESCRIPTION (provided by applicant): A series of coordinating events must occur for an intracellular bacteria to gain entry into and establish infection within its host cell. This application is directed at understanding the molecular signals r
DISSECTING THE ROLE OF ERK AND DUSP OF LEGIONELLA PHEUMOPHILA INFECTION
The lung represents a major interface between the external world and our bodies.  Thus, the lung must be able to effectively resist injurious agents while preventing an over-exuberant inflammatory response.  When this does not occur, unregulate
THE ROLE OF SYNDECAN-1 SHEDDING IN NEUTROPHIL ACTIVATION IN THE LUNG
Infection associated with allograft transplantation and prosthesis use can occur in any patient, and is particularly prevalent and challenging in immunocompromised individuals. When developed, infection can lead to prolonged disability with imm
A new allograft that promotes long-term, infection-free skeletal repair
AMP-activated protein kinase (AMPK) coordinates metabolism with energy availability in eukaryotes by responding to changes in intracellular ATP and AMP levels. The kinase activity of AMPK is stimulated by AMP and inhibited by excess ATP, and it
Structure and mechanism of the AMP-activated protein kinase
The long-term objective of our research is to characterize the molecular and genetic role of GCM2 in controlling parathyroid gland development during embryogenesis and parathyroid cell maintenance after birth. Studies in mice have shown that pa
GCMB- MASTER REGULATOR OF PARATHYROID FUNCTION
There is a very high degree of genetic and physical similarity between humans and the various species of non-human primates and this high degree of similarity can be exploited in medicine to better understand the mechanisms and find new treatme
BETA CELL ADAPTATION TO STRESS IN BABOON PANCREAS AFTER PARTIAL PANCREATECTOMY
This project applies proteomic methodology to analyze peripheral blood samples from patients with hemolytic anemia. Our focus is on evaluation of younger individuals, or those with a family history of anemia, in order to identify novel genetic
Hemolytic Anemia: Biochemical, Molecular and Proteomic Diagnostics
Chronic pancreatitis, a destructive disease of the pancreas, is difficult to diagnosis and can present with a variety of symptoms.  The incidence of chronic pancreatitis is not known; hospital admission and discharge summaries suggest at least
DEVELOPMENT OF CHRONIC PANCREATITIS BIOMARKERS
The gene in question codes for a protein called ?B1? which in its abnormal state will change the composition in the urine resulting in kidney stone formation. We will use human population and laboratory studies to answer three questions. 1. Exa
H+-atpase b-sunbunit dysfunction and calcium nephrolithiasis
Hyperoxaluria is considered to be a major risk factor in calcium oxalate stone disease which occurs in about 12% of the American population and, apart from reducing dietary sources of oxalate, there is currently no pharmacological treatment ava
Mechanisms of Oxalobacter-Induced Enteric Oxalate Excretion
In response to partial outlet obstruction, the urinary bladder is capable of undergoing hypertrophy via a complex remodeling process that allows it to adapt to its new workload. This remodeling is driven by a number of signaling cascades and th
NFAT and MEF-2 Choreograph Bladder Wall Remodeling Following Partial Outlet Obstr
It is estimated that 3.2 million African Americans aged 20 years or older have T2DM. This represents approximately 13 percent of the AA population and a significant proportion of the more than 20 million Americans believed to be living with dia
Genetic contributors to diabetes and dyslipidemia in African Americans
The scanning fiber endoscope is an ultrathin and flexible scope that provides high-resolution by scanning low-power laser light.  By integrating higher-power laser light, early cancers and neoplasia can be imaged and treated with oncologic lase
Pixel-accurate oncologic therapy using a scanning fiber endoscope
Epidemiologic studies have demonstrated that exposure to tobacco products is an important risk factor in the progression of chronic kidney disease (CKD). Among the numerous harmful substances found in tobacco, nicotine is one of the highly acti
The purpose of this proposal is to understand how ectopic signaling through the acetylcholine pathway results in changes that eventually influence adult learning and behavior.  This will involve looking at the influences of exciting acetylcholi
Subsequent effects of manipulating embryonic neuronal activity
To understand the function of organophosphates and interrelationship between environmental toxins and paraoxonase in oxidative stress and inflammation associated with Alzheimer's disease.  The long-term goal of this project is to understand the
Pesticides, Paraoxonase and Alzheimer's Disease
The overall goal of this project is to assess whether exposure to metabolites of endocrine disrupting compounds during pregnancy is associated with a) adverse development (cognitive function, height, weight, weight for height, and for females,
Prenatal Organochlorine Metabolites, Thyroid Function and Development
Massachusetts Department of Public Health (MDPH) received a two year award of $928,138 in direct costs from the National Institute of Environmental Health Sciences to support the Reducing Ethnic/Racial Asthma Disparities in Youth (READY) study.
Trans-NIH Recovery Act Research Support - ARRA
Uveitis, an ocular inflammatory disease of unknown etiology, is a major complication during autoimmune disorders and infections and is associated with severe visual impairment. Uveitis may result from direct involvement of the uveal tract or in
AMELIORATION OF UVEITIS BY ALDOSE REDUCTASE INHIBITION
Efficient visual recognition is critical for many aspects of our lives, and understanding how il is accomplished is essential for any complete theory of the brain. One primary reason for the efficiency of object recognition is its facilitation
Prefrontal: Top Down Contribution to Object Recognition
focusing on the general principles and molecular mechanism of transcription elongation and its regulation by various transcription factors. The primary goals are to obtain the high resolution crystal structures of the transcription complexes b
MOLECULAR MECHANISMS OF TRANSCRIPTION ELONGATION
Bacterial polysaccharides are traditionally viewed as molecules that do not form stable secondary structure and are unable to elicit a protective T lymphocyte-driven immune response. We have recently discovered that one class of polysaccharide
Antigenic Carbohydrate Structure, Function and Specificity
Coupled electron and proton transfer is recognized as the universal principle of primary energy conservation in respiration. Terminal respiratory oxidases are membrane-bound electron- transfer complexes that catalyze the reduction of oxygen to
MOLECULAR MECHANISM OF REDOX DRIVEN PROTON PUMPS
Identification of even a single gene that contributes to a complex trait provides insight into its molecular basis. However, multiple genes need to be identified if different genes affect a trait through different biological processes or pathwa
GENES AND GENETIC INTERACTIONS UNDERLYING PHARMACOLOGICAL VARIATION IN YEAST
This project will focus on the discovery of compounds that act as potent Inhibitors of each of the six ATPases In the proteasome. These proteins use the energy of ATP hydrolysis to unfold proteins destined for degradation by the proteasome and
Chemical Inhibitors of the Proteasomal ATPases
The regulatory nature and physical structure of chromatin are dynamically regulated by post- translational modifications of core histone proteins. The recent discovery of histone demethylases has initiated a rapid increase in our knowledge abou
BIOORGANIC MECHANISMS OF CHROMATIN MODIFYING ENZMES
The purpose of this proposal is to examine the role of internal Ca2+ stores in neurohypophyseal nerve terminals of magnocellular hypothalamic neurons found in the posterior pituitary.  These terminals secrete Oxytocin or Arginine Vasopressin, w
Regulation and Function of Internal Ca2+ Stores in Nerve Terminals
The broad goal of the proposed research is to extend our understanding of the functions of the cyclooxygenase enzymes (COXs, prostaglandin H synthases). These enzymes participate importantly in many physiologic functions and diseases, including
Lipid Modification of Proteins by the PGH Synthases
WEST VIRGINIA UNIVERSITY RESEARCH CORPORATION
This project is aimed at expanding our de novo synthesis methodology  towards the development of new methods for medicinal chemistry SAR-  studies.  These methods will be applied toward the studies of three   classes of anticancer natural produ
DNA mismatch repair (MMR) is a major contributor to genome stability. MMR corrects DNA biosynthetic errors, ensures the fidelity of genetic recombination and is required for the cellular response to certain classes of DNA damage, including lesi
STRUCTURAL BIOLOGY OF HUMAN DNA MISMATCH REPAIR MACHINERY
ROCKEFELLER UNIVERSITY FACULTY AND STUDENTS CLUB INC, THE
Our long-term aim is to understand how sensory organs form. Sensory structures allow organisms to assess their environment, and sensory organ defects in humans lead to perceptive and psychological deficits. Lumen formation plays key roles in se
Lumen formation during tubulogenesis in C. elegans
Newborn screening with tandem mass spectrometry (MS/MS) has been expanded to detect a number of inherited disorders of metabolism, including lysosomal storage disorders. MS/MS allows the pre-symptomatic detection and early treatment of infants
Mechanisms for immune tolerance in Pompe Disease
The effects of yoga on prenatally depressed women will be tested in this study. Yoga would be expected to reduce depression, enhance vagal activity, reduce cortisol and increase gestational age (reduce premature deliveries) in depressed women.
PRENATAL DEPRESSION AND A YOGA INTERVENTION
Overweight is a serious public health problem that begins as early as toddlerhood, and has negative health and developmental consequences throughout life. Although caregiver-child interaction patterns influence children's growth, most overweigh
The long-term goal of the proposed research is to understand the complex genetic control of determination of left/right (L/R) body axis in the mammalian embryo. Specification of the L/R axis sets up a developmental cascade that coordinates deve
T-box gene effects on left-right body axis determination
In addition to the increase in obesity in adult and children, there has been a significant increase in birth weights over the last 2 decades.  Based on our preliminary data, maternal pregravid obesity is the strongest risk factor for neonatal a
OMEGA-3 SUPPLMENTATION DECREASES INFLAMMATION AND FETAL OBESITY IN PREGNANCY
According to The World Health Organization, iron deficiency is the foremost nutritional disorder in the world. Iron is essential for normal neurological function and iron deficiency results in cognitive and motor impairments that can last throu
IRON ACQUISITION MECHANISMS IN OLIGODENDROCYTES
The project titled “A longitudinal MRI study of brain development in Fragile X syndrome” aims to study very early brain and behavior development at 6, 12 and 24 months in infants with fragile X syndrome (FXS).   Investigators use Magnetic R
A Longitudinal MRI Study of Brain Development in Fragile X Syndrome
This project will take advantage of the existing infrastructure of the PHACS Study which began protocol development in 2005 after successfully competing for funding by the NICHD. This is a multicenter, multidisciplinary and collaborative study.
DIETARY INTAKES AND PATTERNS, BIOMARKERS AND MATERNAL AND INFANT OUTCOMES IN HIV.
This proposal will explore the hypothesis that autism is caused by highly-penetrant, rare mutations using emerging technologies that screen regions for autism-specific CNV mutations and exonic point mutations.  Our targeted focus will be 17 gen
DESCRIPTION (provided by applicant): Poorly controlled hypertension (HTN) remains one of the most significant public health problems in the United States, in terms of morbidity, mortality, and economic burden. Despite compelling evidence suppor
Practice-based Trial of BP Control in African Americans
Hypertension remains a hugely costly problem in the United States in terms of morbidity and economic burden. Many patients cannot or will not take medications; the application proposes a non-pharmacological intervention that will help hypertens
PILOT TEST OF A NOVEL BEHAVIORAL INTERVENTION ON BP CONTROL IN HTN PATIENTS
Hypertension affects nearly one-third of adults over age 20 in the United States. While hypertension is found in <10% in adults 20 - 34 years of age, it develops over a period of years, and blood pressure levels in children and adolescents are
GENOTYPES, HAPLOTYPES, AND BLOOD PRESSURE CHANGE FROM CHILDHOOD TO ADULTHOOD
Approximately 7.9 million Americans suffer from heart failure every year. Among these, nearly 2.5 million develop Ischemic Mitral Regurgitation (IMR), a 33% increase since 1995. Even with such high prevalence, little is known of the cause and p
ARRA: ANNULAR AND SUB-VALVULAR REPAIR TECHNIQUES FOR ISCHEMIC MITRAL REGURGITATION
Specifically, the goals of this proposal are 1) to determine whether aging results in uncoupling of eNOS and reduction of bioavailable NO in skeletal muscle resistance arteries, and 2) to determine whether interventional strategies, including a
The long-term goal of this research project is to study the role of AIF in cardiac apoptosis. Although the caspases are thought to be central mediators of the apoptotic program, our preliminary studies have demonstrated that adult cardiomyocyte
APOPTOSIS INDUCING FACTOR IN CARDIAC APOPTOSIS
Continuation-A major contributor to morbidity and mortality in trauma patients following emergency resuscitation is intestinal dysfunction caused by interstitial edema formation in the bowel. The mesenteric lymphatic system plays a crucial rol
SHORT-TERM MESENTERIC LYMPHATIC ADAPTATION TO TRAUMA-RELATED INTESTINAL EDEMA
Dept Veterinary Physiology & Pharmacology
The majority of diseases potentially amenable to gene-based therapeutic approaches will likely require systemic vector administration, especially those with vascular involvement such as metastatic cancer, pulmonary arterial hypertension (PAH) a
DEVELOPMENT OF DOUBLE-TARGETED VECTORS FOR LONG-TERM VASCULAR EXPRESSION IN VIVO
This proposal, entitled ICD Therapy in Patients with Congestive Heart Failure, examines the current use of primary prevention implantable cardioverter defibrillator (ICD) in clinical practice. Although randomized clinical trials have establishe
DCRI #4595 ICD Therapy in Patients with Congestive Heart
The human cutaneous circulation is an accessible, representative vascular bed for in vivo examination of mechanisms that contribute to vascular dysfunction with essential hypertension (HT). This proposal is a logical extension of our previous w
ESSENTIAL HYPERTENSION AND HUMAN SKIN BLOOD FLOW
The primary aim of the proposed study is to explore how the familial and home environment of adolescents is related to adolescent weight-related outcomes. We will examine parental reports of the weight culture (e.g., dieting and weight norms) a
PROJECT F-EAT: FAMILIES AND EATING AND ACTIVITY IN TEENS
Irradiation Damage and Protection of Pulmonary Endothelium Oxidative Lipidomics Radiation exposure leads to the development of severe acute inflammatory response and late damage to the lung culminating in delayed fibrosis. Pulmonary endothelium
Irradiation Damage and Protection of Pulmonary Endothelium Oxidative Lipidomics
After biosynthesis within the fibroblast, a procollagen molecule is secreted into the extracellular space where it must undergo a series of very ordered, time sensitive, and location sensitive sequential post-synthetic processing steps in order
Post-Synthetic Procollagen Processing in Load-Induced Left Ventricular Remodeling
COAGULATION ACTIVATION IN SICKLE CELL DISEASE ARRA: This study seeks to further define the contribution of coagulation activation to the pathogenesis of sickle cell disease-associated pulmonary hypertension. Patients in the clinical study will
COAGULATION ACTIVATION IN SICKLE CELL DISEASE ARRA
During embryogenesis, the heart develops functional left-right (LR) asymmetries. Perturbation of cardiac LR asymmetry, or laterality, often leads to complex congenital heart defects. There is strong evidence that ciliated cells play a role in e
ARRA: Regulation of Ciliated Cells that Control Cardiac Laterality
Coronary artery disease (CAD) is the leading cause of the death in the US and, in concert with the epidemic of obesity and diabetes, is becoming the leading cause of death in many developing countries. The genetic predilection of CAD is well-es
METABOLOMIC QUANTITATIVE TRAIT LOCUS (mQTL) GENETIC MAPPING IN HUMAN CVD
Although the sequencing of the human genome promised to transform basic and translational research, the catalogue of human genes that it delivered remain far from the type of predictive models that would allow us to rapidly develop hypotheses a
Integrated approaches to deriving predictive networks from public data sources
Neuroinflammation in the central nervous system (CNS) is an important aspect of CNS injury, disease and neurodegeneratlon. The CNS production of proinflammatory cytokines and other neuroimmune molecules is thought to playa role in cognitive, be
IL-6 Regulation of Hippocampal Synaptic Function
This is an application for support from the Recovery Act Limited Competition for NIH Grants: Research to Address the Heterogeneity in Autism Spectrum Disorders (R01) RFA-MH-09-170. We propose to leverage ongoing collaboration among faculty at D
A MACAQUE MODEL OF SOCIAL BEHAVIOR HETEROGENEITY IN AUTISM SPECTRUM
This application proposes to study a large cohort of children with autism using a multidisciplinary analytic approach in order to identify biological signatures that define distinct phenotypes of autism. We propose that subtypes will be identif
Interdisciplinary Investigation of Biological Signature of Autism Subtypes
Prion diseases are fatal neurodegenerative disorders of humans and animals. They result from conversion of PrPC, a normal membrane glycoprotein into PrPSc, a conformationally altered isoform that is infectious in the absence of nucleic acid. Mo
The relevance to public health is that the project will enhance our understanding and provide new insights into mechanisms for chromosomal abnormalities that result from nonrecurrent rearrangements. Such genome rearrangements cause gene copy nu
Nonrecurrent rearrangements, genome architecture and neurodegenerative disease.
Stroke is a major cause of death throughout the world and its prevalence is increasing with increased longevity and obesity-associated vascular disease. There are, however, very few effective therapeutics. During the last few years we have iden
A novel family of neuroprotective compounds for stroke
Rapid eye movement (REM) sleep is a behavioral state characterized by activation of the cortical and hippocampal EEG, rapid eye movements and muscle atonia. While some progress has been made in recent years in the effort to delineate 1) the loc
PONTINE CIRCUITRY REGULATING REM SLEEP AND ATONIA
The objective of this study is to identify how the suppression of reflex function by antispastic agents affects volitional movement in people with incomplete spinal cord injury (SCI). Spastic reflexes are commonly treated using medications or o
REFLEX REGULATION OF MOTOR FUNCTION IN HUMAN SCI
Neurodegeneration associated with brain iron accu ulation (N BIA) comprises a heterogeneous group of disorders, such as infantile neuroaxoal dystroph (INAD), in which disruption of cellular mechanisms leads to accumulation of iron in the b sal
MECHANISMS OF NEURODEGENERATION AND BRAIN IRON ACCUMULATION
Injuries to the brachial plexus result in the reduction or loss of use of the upper extremities due to damage to the brachial nerves and/or spinal roots.  These injuries are usually the result of vehicle accidents or falls.  Peripheral nerve gr
REPAIR OF BRACHIAL SENSORY ROOT INJURIES IN THE SPINAL CORD
A-kinase anchoring proteins (AKAPs) organize numerous intracellular signaling pathways by bringing together their molecular components into discrete sub-cellular microdomains. One such AKAP, AKAP79/150 interacts with protein kinase A, protein k
MECHANISM AND FUNCTIONAL ROLE OF AKAP79/150 IN M CURRENT CONTROL AND EXCITABILITY
Incidences of heart diseases are increased with age and cardiac diastolic dysfunction and diastolic heart failure are more often found in the elderly. This study is to investigate whether chronic left vagus nerve stimulation (CLVNS) can improve
Vagus Stimulation Protects against Cardac Diastolic Dysfunction in Aging Mice.
Project is designed to evaluate the cell-mediated immune (CMI) response in non-human primates that have been immunized against SIV Gag, Pol, Nef. Specifically, we will perform ELISpot and cytometric flow separation studies to determine the leve
Evaluation of Ad5-gag & Innovative Ad5-E2b-gag Vaccines in Ad-immune Cynomolgus Macaques
The maturation of dendritic cells (DCs) in response to a pathogen is essential for effective immune-mediated control of the infection and protection from subsequent re-infections. Pathogenic viruses have developed strategies to evade immune rec
INITIAL STUDY OF THE DENDRITIC CELL RESPONSE TO SEV DI PARTICLES
Numerous infectious diseases are caused by minority strains within otherwise nonpathogenic species, but the ecological and population genetic mechanisms that drive their emergence remains unclear. Understanding these dynamics is especially impo
Ecological population structure and emergence of virulent Vibrio parahaemolyticus
More than 10 million cancer survivors are alive in the US today, and there is a need to promote the health and well being of these individuals. While several studies have shown that physical activity is associated with better quality of life in
Physical Activity and Survival in Cancer Patients
Layman's abstract: Women with a history of preeclampsia in pregnancy are at reduced risk of breast cancer, especially those who delivered a son, not a daughter, from the pregnancy. Why is this so? We compare hormones in the blood of a group of
PREECLAMPSIA AND SUBSEQUENT BREAST CANCER RISK: HORMONAL AND GROWTH FACTOR BIOMAR
Title: DNA Damage Response Markers in Barrett’s Esophagus  Abstract:  The incidence of esophageal adenocarcinoma (EAC) in the United States is increasing markedly. Five-year survival remains a disappointing 15%. Better methods are urgently ne
DNA DAMAGE RESPONSE MARKERS IN BARRETT'S ESOPHAGUS
Circadian disruption has been implicated as a significant contributor to the increasing incidence of many modern maladies such as breast cancer. Proposed here is a small, sophisticated study of the absolute and spectral sensitivities of two str
Light as a Controlling Stimulus for Behavior Cancer Research: Bridging Human Exposures to Animal Models for Parametric Investigations
) than smokers. During temporal discounting when both reward alternatives are delayed, we predict that nonsmokers will also exhibit higher levels of activation in the areas compared to smokers. The PI is already engaged in funded research exami
Imaging temporal discounting in smokers and nonsmokers
ROLE OF DARPP-32: INDIVIDUAL RESPONSIVENESS TO NICOTINE Tobacco use is the number one preventable cause of death in the world. Nicotine (NIC), the most abundant alkaloid in tobacco, is the primary reinforcing agent in tobacco smoking. Many fact
ROLE OF DARPP-32: INDIVIDUAL RESPONSIVENESS TO NICOTINE
The discovery of compounds capable of preventing cocaine?s harmful properties with minimal physiological effects is a promising area of research.  Cocaine abuse is intensively studied; however, there are no proven pharmacological treatments for
Cocaine-induced planarian behavior and its modulation by sesquiterpene lactones
Methamphetamine (METH) addiction is a global problem, and has now reached epidemic proportions in certain Western, Midwestern, and Southern states including North Carolina. Total abstinence from METH is very difficult to achieve in the clinic,
PKC ZETA-SPECIFIC INHIBITORS FOR TREATMENT OF METHAMPHETAMINE ADDICTION
). Using knock-in mice carrying point mutations in the ?1, ?2, or ?3 subunit rendering the respective GABAA receptors insensitive to modulation by diazepam and zolpidem, we will dissect the contribution of individual receptor subtypes to the re
GABAA subtype-specific pharmacological modulation of reward-related behavior
This A-START application proposes formative research aimed at understanding the role of illicit drugs in the transmission dynamics of sexually transmitted infections (STIs) and HIV among 18-30 year old African Americans (AA) living in high-risk
Formative Research to Understand High Risk Community Sex networks
Chronic obstructive pulmonary disease (COPD) includes both emphysema and small airway disease. COPD has typically been defined based on a reduction in the FEV1/FVC ratio, with the severity of COPD determined by the level of reduction in the FEV
Unclassified Spirometric Abnormalities: Radiology, Epidemiology, and Genetics
Micro RNA Regulation of Human Airway Epithelial Phenotype ? ARRA  Greater than (<) 22 million people in the USA currently have asthma and <15 million people have chronic obstructive pulmonary disease.   Along with less common obstructive lung d
Micro RNA Regulation of Human Airway Epithelial Phenotype - ARRA
This application addresses broad Challenge Area (15) Translational Research and specific Challenge Topic 15-OD(ORDR)-101: Pilot projects for prevention, early detection and treatment of rare diseases. This Challenge Grant application is focused
Determinants of Disease Expression in Arrhythmogenic Cardiomyopathy
This application, 'Epigenetic Biomarkers of Common Chronic Diseases,' addresses broad Challenge Area (03) Biomarker Discovery and Validation and specific Challenge Topic, 03-OD-101: Use of Epigenetic Signatures in Blood Cells to Predict Disease
EPIGENETIC BIOMARKERS OF COMMON CHRONIC DISEASES
This application addresses broad Challenge Area 04, Clinical Research, and Specific Challenge Topic 04-HL-114, Using existing datasets to plan effectiveness trials in pediatric cardiology.  This challenge topic specifically identifies a critica
Comparative effectiveness of ECG screening in children with Attention Deficit Hyperactivity Disorder
Overweight and obese adults are more likely to have hypertension and other risk factors for cardiovascular disease (CVD). Evidence-based medication and lifestyle strategies can be used to decrease CVD risk, but little is known about the compar
Collaborative Behavioral e-Care to Decrease Cardiovascular Risk (e-Compare)
The assessment of proper and effective ventilatory function in premature newborns suffering from respiratory distress secondary to surfactant deficiency is difficult, and only crude measures are currently available. In part this arises from the
This award is issued under the American Recovery and Reinvestment Act of 2009 and is subject to special HHS terms and conditions as referenced in Section III.
Sudden Cardiac Death in Heart Failure Trial 10 Year Follow-up (SCD-HeFT 10 Yr.)
Pilot Studies of Gene Therapy for Primary Ciliary Dyskinesia - ARRA  	The long-term goal of this research is to develop gene therapy as a treatment for the rare disease Primary Ciliary Dyskinesia (PCD). PCD is predominantly inherited as an auto
Pilot Studies of Gene Therapy for Primary Ciliary Dyskinesia - ARRA
This project addresses how to develop cell-based therapies for cardiovascular, lung and blood diseases. The specific aims are 1) Assess long term persistence characteristics of Pim-1 engineered stem cells in promotion of myocardial repair and r
ARRA: Engineering Cardiac Progenitor Cells to Enhance Myrocardial Regengeration
The proposed application under this challenge grant seek to answer the following questions: (1) What is the incremental cost-effectiveness of SPECT, PET, and CCTA as well as their respective accuracy for identification of obstructive CAD, and c
Comparative effectiveness of noninvasive cardiac imaging
This proposed study plans to enhance and evaluate IT infrastructure developed to provide timely genetic variant updates and patient search functionality to clinicians to assist in optimizing patient care. Partners HealthCare has deployed and is
Refining IT support for Genetics in medicine
This project addresses the Challenge Area 15: Translational Science. The Challenge Topic is 15-TW- 101: Models to predict health effects of climate change. The slow but steady increase in the global mean temperature as a result of climate chang
Improved Tracking for Emerging Diseases from Climate Change
Overall purpose: to determine whether cancer diagnosis is an influence on personal bankruptcy.  Deliverables:   a.  Linkage of Western Washington Bankruptcy Court records to cancer records in the National Cancer Institute?s Surveillance, Epidem
A Study of Cancer Diagnosis as a Risk Factor for Personal Bankruptcy
This application addresses broad Challenge Area (09) Health Disparities and specific Challenge Topic 09-MD- 102 Trans-disciplinary Research to Integrate the Biological and Non-biological Determinants of Health to Address Health Disparities. Des
Bio-behavioral chronic disease management by families of young minority children
Although the development of new therapeutic modalities against CVD has reduced overall CVD mortality by nearly 50%, the gap between certain minority groups and non-minority groups has not diminished. There is preliminary evidence, including our
IMPROVING ADHERENCE TO POST PCI ANTIPLATELET THERAPY IN MINORITY POPULATIONS.
This application responds to broad challenge grant area (04): Clinical Research & specific Challenge Topic, 04-MD-101: Enhancing Recruitment & Retention of Ethnic Minorities in Clinical Trials. Sickle cell disease (SCD) is a genetic disorder af
IDENTIFYING STRATEGIES TO INCREASE ENGAGEMENT IN CLINICAL TRIALS IN PEDIATRIC SCD
The Committee on Adolescent Health Care Services, the National Research Council, and the Institute of Medicine have identified adolescents with chronic disease as one of the ?most vulnerable? groups of adolescents.  Studies to date demonstrate
TAHLC:TEXTING TO PROMOTE ADOLESCENT HEALTH LIAISONS & CHRONIC DISEASE MANAGEMENT
This grant responds to NIH Challenge 08-MH-103: Understanding the Genomic Risk Architecture of Mental Disorders. This application builds on recent animal and human data on epigenetic mechanisms mediating 'glucocorticoid programming' to address
IDENTIFICATION OF AN EPIGENETIC RISK MARKER FOR PTSD
This application addresses broad Challenge Area (06) Enabling Technologies and specific Challenge Topic, 06-MH-102: Technologies to study neuronal signaling, plasticity, and neurodevelopment. The complex and diverse functions of the brain depen
OPTOGENETIC MICE FOR CELL TYPE-SPECIFIC MANIPULATION OF NEURONAL ACTIVITY
Youth with mental health needs during the transition to adulthood have tremendously compromised functioning in working, living independently, and staying out of trouble with the law. Office-based mental health treatment is accessed by 760,000 t
Treatment Retention Strategies in Transition Age Youth
This project develops tools to address two hypotheses: first that specific types of neurons in localized brain regions or subregions can be altered so that they are susceptible to reversible inactivation or activation in response to systemicall
NOVEL METHODS FOR VAST INCREASE IN THROUGHPUT AND ACCURACY OF CIS-REG ANALYSES
This application addresses Broad Challenge Area 01 Behavior, Behavioral Change, and Prevention. The specific topic is: Capturing Social Network Information for Groups at High Risk for Negative Health Behaviors; OD-09-003. Latinos in the United
Network Determinants of Risk Among Formerly Incarcerated Latino Men
COLD SPRING HARBOR LABORATORY ASSOCIATION, INC.
This application addresses broad Challenge Area (15): Translational Science and specific Challenge Topic,15- MH-103 Mapping the Neural Connectivity of a Mouse Model. Brain function is dictated by its circuitry, yet we know little about its wiri
THE FIRST COMPREHENSIVE NEURAL CONNECTIVITY MAP OF MOUSE
This application addresses broad Challenge Area (08) Genomics and specific Challenge Topic, 08- MH-103: Understanding the genomic risk architecture of mental disorders. Rett syndrome (RTT), caused by mutations in the X-linked gene encoding meth
Cell-Based Genomic Ananlysis in Mouse Models of Rett Syndrome
This application addresses the broad Challenge Area (05) Comparative Effectiveness Research (CER) and the specific Challenge Topic (05-MH-102) Cost Effectiveness of Mental Health Interventions.  This study will conduct comparative cost-effectiv
Cost-Effectiveness of HIV-Related Mental Health Interventions
The goal of this Challenge grant application is to identify novel biomarkers of clinical severity in patients with schizophrenia. The identification of such biomarkers will not only increase our knowledge of the pathophysiology of schizophrenia
Genetic Markers of White Matter Integrity in Schizophrenia: Relationship to Clinical Severity
The blurring of the distinction between treatment and research in the minds of participants in phase 3 clinical trials has been referred to as therapeutic misconception (TM). This has been widely recognized as a major problem for informed conse
The Blurring of Treatment and Research in Clinical Trials: two problems
Communication in Late-stage Cancer: Exploring Hospice Decisions This application addresses broad Challenge Area (04): Clinical Research and specific Challenge Topic, 04-NR-103*: Methods to Enhance Palliative Care and End-of-Life Research. Estim
ARRA: Communication in Late-Stage Cancer: Exploring Hospice Decision
for a new therapeutic approach in a neurological disease: 15-NS-103. Parkinson's disease (PD) is a chronic, progressive neurodegenerative disorder characterized by degeneration of dopaminergic neurons located within the substantia nigra, pars
DBS OF THE PEDUNCULOPONTINE NUCLEUS IN PARKINSONIAN PRIMATE
The long- term objective of this project is to use new technologies to sensitively measure, automatically analyze and efficiently manage clinical trial data for Parkinson's disease (PD) and other neurological disorders. This project will focus
Development of an Instrumented System to Measure Mobility in Parkinson's Disease
The blood brain barrier (BBB) is a significant barrier to delivery of drugs to the central nervous system (CNS) and in removal of potential toxins produced within the CNS (e.g. beta-amyloid).  In contrast to the endothelial cell barrier in othe
DRUG INTERACTIONS AT THE HUMAN BLOOD-BRAIN BARRIER
Glioblastoma is the most common primary brain tumor and is considered to be among the deadliest of human cancers. The metabolism of the cells is much higher than normal cells and, like many cancers, represents a possible target for new drugs in
Genotype and Metabolic Phenotype in Glioblastoma-ARRA Stimulus Challenge Grant
This work addresses broad Challenge Area (15) Translational Science, and specific Challenge Topic Applied Translational Technology Development. Mechanical ventilation is a life support procedure that is indicated for a wide variety of acute or
People expect their primary care physician to be their point of access to healthcare and to assure that the care they receive within the system is evidence-based, cost-effective, coordinated, and safe. Unfortunately, primary care providers do n
A MEDICAL HOME PILOT EVALUATION: A MODEL FOR COMPARATIVE EFFECTIVENESS RESEARCH
We are proposing to evaluate the efficacy of the sustained Vanderbilt University-Metropolitan Nashville Public Schools-Tennessee State University-Meharry Medical College-Fisk University GK12/Scientist in the Classroom Program (SCP) on the long-
Evaluation of the Impact of a Sustained Scientist-in-the-Classroom Program
The purpose of this project is to develop and implement fout culturally adaptive distance education courses that can enhance productivity and quality of active U.S.-international research and research training collaborations.  The courses are b
DISTANCE-BASED EDUCATION FOR INTERNATIONAL STUDY COORDINATORS
This is a GO application to address 'Mechanisms of Alcohol and Nicotine Co-Dependence' as the area of scientific priority. The GO mechanism is used because this application requires a multi-lab approach to accelerate current and future research
Ethanol and nicotine co-abuse: cross sensitization of their reinforcing actions
Alcoholic Liver Disease (ALD) remains a major cause of alcohol-related morbidity and mortality.  15-30% of heavy drinkers develop advanced ALD, over 25,000 deaths occur annually related to liver disease, and over 40% of those are attributed to
Hepatocellular carcinoma (HCC) develops synergistically in HCV-infected patients with alcoholism, and no treatments are available for this devastating complication. Our study reveals the role of TLR4-dependent Nanog+ cancer stem cells (CSCs) in
TLR4 and TGF-beta Interactions in HCC Induced by HCV and Alcohol
This proposal brings together a unique multidisciplinary team of leading experts in alcohol studies and real time dynamic fluorescence imaging of cells and subcellular structures in intact tissues, high resolution electron tomography, sophistic
ER mitochondrial signaling and alcoholic tissue injury
A Grand Opportunity for scientific advance has been created by the confluence of falling costs of genotyping, the development of statistical methods for genome-wide association studies (GWAS), and the creation of a substantial repository of gen
CREATING A NATIONAL RESOURCE FOR GENETIC RESEARCH IN BEHAVIORAL & HEALTH SCIENCES
We propose to study US trends in the prevalence of cognitive impairment and dementia by performing a new Aging, Demographics, and Memory Study (ADAMS 2010) that uses a similar methodology to that employed for the original NIA-funded study perfo
NATIONAL TRENDS IN BRAIN HEALTH: A FOLLOW-UP STUDY OF CIND AND DEMENTIA IN THE US
Age-related illnesses present major public health challenges due to their increasing prevalence, associated disability and current lack of effective therapies. The broad, long-term goal of this project is to understand the role of aging physiol
Neurodegeneration and Synaptic Transmission in Aging
The proposal brings together the complementary strengths of three labs to develop and test a new set of molecular tools that will globally report on the health of the proteome during aging. These groups form the Proteostasis Aging Sensor Consor
Sensing Protein Folding Capacity in the Cell During Aging
Genome-wide association scans (GWAS) in human SLE have identified DNA segments that likely harbor causal variants, however, the precise identities of these variants have remained elusive.  The primary objective of this 'Grand Opportunity' propo
Candidate Causal Variants in Systemic Lupus Erythematosus
In order to make these studies possible, the scientific community will require the repeated participation of a large numbers of normal subjects who carry polymorphisms of interest and are willing to be studied. This proposal will make such a po
Genes and Phenotype (GAP) studies of immunologic and inflammatory pathways
The broad potential for using nucleic acids to treat human disease has not been realized. Delivery of nucleic acids for the purpose of regulating gene expression in cultured cells has been routine in many laboratories for twenty years. Over 350
Delivery of biologically active nucleic acids to epidermal cells
Over the past several years, there has been a dramatic increase in the scientific scrutiny of omega-3 fatty acids and their impact on health. Results indicate that omega-3 fatty acids have potent anti-inflammatory actions. Inflammation is at th
MECHANISMS OF ACTION OF OMEGA-3 FATTY ACIDS IN BRAIN INJURY
Natural products represent an excellent source of novel chemical scaffolds that are inherently biologically active. It has been estimated that 78% of the 90 antibacterial agents and 62% of the 79 anticancer agents approved for use in the US ove
Creation of a Marine Natural Products Library to Enhance Life Science Research
The 20% rarest cancers account for approximately 35% of the deaths from cancer in the United States. As a result, a better understanding of the nature of these rare tumors is in the public health's best interest. We study sarcomas, rare cancers
TRANSLATIONAL RESEARCH STUDIES IN CLINICAL TRIALS OF NOVEL THERAPEUTICS FOR SARCO
CYCORE: CYBERINFRASTRUCTURE FOR COMPARATIVE EFFECTIVENESS RESEARCH
Nanotechnology for Multiplexed and Intraoperative Cancer Detection;  This grant application aims to develop new and innovative technologies for applications in cancer surgery. The main goals are to help the surgeon to delineate tumor margins, t
Nanotechnology for Multiplexed and Intraoperative
MicroRNAs contribute to the pathogenesis of human cancer by regulating the expression of oncogenes and tumor suppressor genes. In fact, loss of miR-15a and miR-16-1 leads to overexpression of BCL2 and MCL1 and the development of CLL, while over
(ARRA) Loss of miR-29s as a predictor of response to demethylating agents
Epstein-Barr virus (EBV) infects over 95% of the adult population worldwide, and has been estimated to be a contributing agent in ~1% of all human cancer.  Its carcinogenic potential is significantly elevated by immunosuppression, as is found i
A Therapeutic Vaccine for EBV-Associated Malignancies
Abstract this project aims to establish a Lung Cancer Mutation Consortium (LCMC) consisting of 13 institutions with a major interest in lung cancer and genomic testing of lung cancer as documented by having major NCI grants in lung cancer. The
In collaboration with scientists at the Unversity of Texas MD Anderson Cancer Center, we will test our immunotherapeutic approach to treating HPV related cancers in a non-human primate model. This study fulfills the premises of the Grand Opport
Immunotherapeutic HPV cancer vaccines that target Langerhans cells.
This application, for a Research and Research Infrastructure 'Grand Opportunities' (GO) grant (RFA- OD-09-004) will focus on 'Comparative Oncology Research' and requests funds for a unique state of the art PET insert for an MR animal scanner wh
MR-PET for a Small Animal Imaging Center
Recent studies of addiction have highlighted several regions of the brain that are thought to be involved in goal directed  and  drug  seeking  behaviors.  The  specific  neuronal  classes  involved  in  the regulation  of  these behaviors  are
Translational and epigenetic profiling of cell types associated with addiction
This application is submitted in response to an RFA-OD-09-004 entitled 'Recovery Act Limited Competition for NIH Grants: Research and Research Infrastructure 'Grand Opportunities' (RC2)' and addresses the NIDCR Area of Scientific Priority 'Geno
GENOME-WIDE ASSOCIATION STUDY OF PERIODONTITIS
The purpose of the study is to evaluate the efficiency of a risk assessment algorithm in identifying subjects with suspicious pre-cancerous or cancerous lesions in high risk population, as compared to broad screening in the general population.
Oral Cancer Detection Methods in a Community Setting
Head and Neck Squamous Cell Carcinoma (HNSCC) is a disease with significant morbidity and mortality, and without reliable indicators for prognosis, local recurrence, or presence of premalignant disease. This project is focused on validation of
VALIDATION OF EPIGENETIC BIOMARKERS OF HEAD AND NECK CANCER PROGRESSION--OLD
For this ARRA RFA-OD-09-004 GO application, we propose to perform an integrated genome-wide mutational analysis of oral cancers using high throughput sequence analysis of coding genes combined with analyses of copy number, gene expression, and
GENONE-WIDE DISCOVERY OF MOLECULAR ALTERATIONS IN HEAD AND NECK CANCER
Previous studies in rats have provided evidence that brief, early-life exposures to bisphenol A (BPA) at environmentally relevant doses results in developmental reprogramming of the prostate gland via epigenetic modifications that enhance carci
Developmental exposure to low dose bispherol A and Human prostrate cancer susceptible
Medicinal plants produce a wealth of pharmaceutical compounds such as taxol, vincristine, and morphine. Unfortunately, the specialized secondary metabolic pathways leading to such compounds remain poorly understood and progress in elucidating a
Advancing Drug Development from Medicinal Plants using Transcriptomics and Metabolomics
The overall goal of this initiative is to investigate the cellular uptake, trafficking, and sub-cellular localization of different classes and subtypes of nanoparticles (NPs) with well-defined physiochemical properties for the creation of a ref
Exploration with DNA chips of the genome’s activity holds great potential for human health. Using a combination of high-throughput genomics and computational biology, we will perform a broad exploration of gene expression in human blood cells
Gene Expression and Regulatory Networks in Human Leukocytes
Neonatal apnea, or apnea of prematurity, is the most common serious disorder of premature infants in the neonatal intensive care unit (NICU). There are significant gaps in knowledge in its definition, documentation and management. For example,
Neonatal apnea: Online risk score from new analyses of bedside monitor waveforms
Next-generation sequencing produces huge amounts of data that require significant investments in computation resources and data storage to convert sequencing instrument output into biomedical knowledge.  Such large data center investments can p
Development of a Software Pipeline for Sequence Data
DESCRIPTION (provided by applicant): This application responds to NHGRI's call for Medical Sequencing Discovery Projects that will use next-generation sequencing technology to tackle high-impact challenges in medical genetics. We propose to bui
GENETICS OF LIPID LEVELS: DRAFT SEQUENCING OF 1000 GENOMES
This proposal responds to the GO Program 'ARRA Medical Sequencing Discovery Projects' to establish next-generation technologies for medical resequencing in smaller academic laboratories compared to larger facilities like the Genomic Sequencing
NEXT-GENERATION MEDICAL RESEQUENCING OF GOUT DISEASE GENES IN THE ARIC COHORT
Chronic obstructive pulmonary disease (COPD) is a key health condition. Comparative effectiveness research (CER) is underdeveloped, particularly in COPD. The development of a high impact CER research agenda requires a collaborative infrastructu
The aim of this two-year 'Grand Opportunities' ('GO') proposal is to construct a detailed and comprehensive profile of the molecular biology of cardiac function in a hibernating mammal. In compliance with 'GO' program requirements the proposed
Genetic Control of Heart Function in a Hibernating Mammal
Patients with an acute coronary syndrome (ACS) and comorbid depression have a 2-fold higher risk for recurrent ACS and mortality, worse quality of life, and higher costs of care than nondepressed ACS patients. The strength of these findings pro
Comparison of Depression Interventions after Acute Coronary Syndrome (CODIACS)
Heparin is a sulfated polysaccharide mixture that is widely used as baseline therapy in a number of clinical situations, especially for preventing thrombosis. While heparin has been administered in the clinic for the past several decades, recen
Characterization of Anticoagulant Heparin and Related Polysaccharides
Recent research on Very Low Birth Weight (VLBW) infants suggests that genetic factors account for 50 ? 80% of the variance in their susceptibility to bronchopulmonary dysplasia (BPD).  Because California has for the past 3 decades stored Guthri
Genomic Influences on Bronchopulmonary Dysplasia-A Population-Based Study
This project has the following specific aims: 1) Determine methods for shipping Notch-mediated expanded cord blood progenitor cells to outside centers for infusion, including preclinical evaluation of in vivo repopulating ability in our establi
CTRIP:NOTCH-MEDIATED EXPANSION OF CORD BLOOD PROGENITORS FOR CORD BLOOD TRANSPLAN
DESCRIPTION (provided by applicant): Our goal is to create a Master Person Index (MPI) that unambiguously identifies each individual who receives health care in the State of Utah. This index will enable qualified clinical and translational rese
DEVELOPMENT OF A STATEWIDE MASTER PERSON INDEX
Specific aims: 1) Establish a diverse coalition of policy makers, community members, and representatives and stakeholders from multiple systems and sectors¿economic development, business, education, labor, housing, transportation, environment,
NORTHSHORE UNIVERSITY HEALTHSYSTEM RESEARCH INSTITUTE
This study aims to uncover informatin about differences in gene expression between individuals with schizophrenia versus controls, their relationship to previously studied genetic variation, and the joint analysis thereof.  Besides informing im
Joint Mapping of Genome-Wide Gene Expression and Association in a Schizophrenia Dataset
The function of the nervous system is dependent on complex interactions between networks of neurons composed of multiple neuron types. Understanding how these networks function both in health and disease is dependent on understanding the precis
Tools for Mapping Mammalian Nervous System Connections with Modified Rabies Virus
In 2005, Science magazine identified understanding organ regeneration as one of the top 25 unanswered questions in science. For over 400 years scientists have been studying the amazing regenerative capacity of the Axolotl or Mexican Salamander.
Validation of a Novel Genetic Model for Neural Regeneration
We have developed a plan for a NINDS research organization/consortium to develop, characterize and study iPS cell lines for Parkinson's disease (PD). The overall goal of this consortium of multiple- Pis (see leadership plan) is to organize the
This application, entitled 'The Role of Rare Variants in Multiple Sclerosis Risk', addresses Research and Research Infrastructure 'Grand Opportunities'. Many human autoimmune diseases, including multiple sclerosis (MS) are complex genetic disor
The Role of Rare Variants in multiple sclerosis risk
This application addresses broad Challenge Area (04): Clinical Research and specific Challenge Topic 04-AG-107: Mechanisms of specific benefits of different types of physical activity. MECHANISMS AND FUNCTIONAL OUTCOMES OF EXERCISE PROGRESSION
MECHANISMS AND FUNCTIONAL OUTCOMES OF EXCERCISE PROGRESSION MODELS IN THE EDERLY
The human malaria parasite, Plasmodium falciparum, possesses a broad repertoire of proteins that are proposed to be trafficked to the erythrocyte cytoplasm or surface, based upon the presence within these proteins of a signal peptide followed b
The Plasmodium 2TM and PHIST protein families
Ndy1/KDM2B is an enzyme that functions as a regulator gene expression by modifying histone molecules. By repressing genes involved in cell differentiation, Ndy1/KDM2B contributes to the cycling of stem cells, and when deregulated, it contribute
The role of Ndy1 in epigenetic gene silencing and stem cell biology
The long-term objective of this research program is to understand how mutations in the ABCC8 gene that encodes the regulatory subunit of the neuroendocrine type ATP-sensitive potassium (KATP) channel, SUR1, cause neonatal diabetes (ND). The two
A Computational Genotyping System for Improved Influenza Surveillance. The long-term goal of this research is to better understand how influenza A viruses evolv, spread, and cause disease, so that enhanced diagnoses and ultimately control strat
A Computational Genotyping System for Improved Influenza Surveillance.
The goal of the current proposal is to obtain funds for the purchase of a high-resolution ultrasound micro- imaging system designed specifically for non-invasive small animal research. The Visualsonics Vevo 770 offers spatial resolution down to
SHARED INSTRUMENTATION: VEVO 770 ULTRASOUND SYSTEM
The ability to identify protein post-translational modifications (PTMs) in complex biological samples is increasingly important in modern biomedical research. This proposal requests funds for the purchase of a ThermoFisher LTQ Orbitrap XL Mass
Acquisition of a High Resolution Orbitrap Mass Spectrometer for Analysis of Protein modification
Funding is requested for a high resolution 9.4T magnetic resonance (MR) scanner to serve and expedite in vivo animal research at the Dartmouth College and Dartmouth Hitchcock Medical Center (DHMC). The NIH funded research programs that will exp
9.4 Tesla Magnetic Resonance Imaging Scanner
BD BIOSCIENCES LSR II FACS FOR THE UNIVERSITY OF SOUTH CAROLINA This proposal requests $277,596 to purchase a BD Biosciences LSR II FACS system. The system will be housed in the Instrumentation Resource Facility (IRF) of the University of South
BD BIOSCIENCES LSR II FACS FOR THE UNIVERSITY OF SOUTH CAROLINA
Glycoconjugates play crucial roles in many fundamental biological processes, and changes in glycan structure correlate with certain diseases and disorders. The large number of biological activities attributed to glycans is due in part to their
SHARED INSTRUMENTATION GRANT: LTQ LINEAR ION TRAP MASS SPECTROMETER
Many physiological parameters affecting human health and disease, including the sleep/wake cycle, core body temperature, hormonal secretion, cardiovascular function, respiration, and metabolism exhibit daily rhythms that are generated by an int
Bioluminescence/Fluorescence Imaging System for Long-Term In Vivo Recording
The award is to purchase/upgrade two NMR spectrometers for use in the Chemistry Department at Boston College. To that end we have negotiated with Varian Instruments for a upgrade to an existing 400 MHz spectrometer (all but the magnet is new) a
Purchase of two 400 MHz NMR spectrometers
This application is for support to purchase a Leica AM TIRF (total internal reflection fluorescence) microscope system. The instrument will be housed within the - Facility of the Kimmel Cancer Center of Thomas Jefferson University. This Facilit
Total Internal Reflection Flourescence Microscopy System
Funds are requested to purchase a state of the art console and gradient amplifiers for a small animal magnetic resonance imaging (MRI) and spectroscopy scanner.  The new instrumentation will be interfaced to an existing vertical bore 9.4 T, 8.9
CONSOLE AND GRADIENT AMPLIFIERS FOR A 9.4 T VERTICAL BORE MRI%2FMRS SYSTEM
SCHOLARSHIP FOR DISADVANTAGED STUDENTS - COP/PARENT GRANT
The Center on Aging and the Life Course at Purdue University seeks support for an interdisciplinary, pre- doctoral research training program. The proposed institutional National Research Service Award (NRSA) is designed to build upon recent ins
Interdisciplinary Research on Aging and the Life Course
Scholarship awards will be disbursed to economically disadvantaged health professional students.
Howard University Scholarships for Disadvantaged Students.
Broad spectrum anti-viral agents are being developed for the treatment of hemorrhagic fevers caused by use of arenaviruses as biological weapons. The new anti-viral agents are human antibodies that eliminate virally-infected cells and viruses,
Broad Spectrum Treatment of Hemorrhagic Arenaviruses - ARRA Stimulus 2 Yr Resub
No research with a Highly Pathogenic Agent or Select Agent has been performed or is planned to be performed under this grant.  Surrogate strains with low pathogenicity will be used to evaluate such agents.  Bacillus anthracis, Francisella tular
Novel antiobiotic development for biodefense
Infection of children with Shiga toxin (Stx) producing Escherichia coli (STEC), primarily a food and waterborne aquired disease, is the leading cause of hemolytic-uremic syndrom (HUS) in the US. There is no specific treatment to prevent or amel
Development of Aptamer-based therapy against HUS
Tufts University Cummings School of Veterinary Medicine
Characterization of Therapeutic human monoclonal antibodies against SARS-CoV.    Aim-1. /To characterize the relative binding affinities and specificities of human monoclonal antibodies against SARS-CoV. /*/ /We will identify a subset of HmAbs
Characterization of Therapeutic Human Monoclonal Antibodies against SARS
THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK
Patient Reported Outcomes (PROs) are a necessary component of medical research and practice.  The NIH-sponsored Patient-Reported Outcome Measurement Information System (PROMIS) has developed item banks and scales for several domains of symptoms
ARRA: Ecological Validity of PROMIS Instruments
Centers for Disease Control and Prevention
Childrens Health Systems Inc., the foundation established by leadership of the American Academy of Pediatrics- California, has been awarded ARRA funding to develop vaccine safety communication materials and curriculum for medical residents. Tar
American Recovery and Reinvestment Act (ARRA) Partnerships to Address Immunization Training and Information Needs of Health Department Staff, Coalitions, Nurses and Medical Residents.
Although overall childhood immunization rates are high some parents defer or decline vaccinations for their children because of their concerns about vaccine safety.  Research has shown that physician recommendations greatly influence parents in
American Recovery and Reinvestment Act (ARRA) Partnerships to Address Immunization Training and Information Needs of Health Department Staff, Coalitions, Nurses, and Medical Residents
Patients with active ulcerative colitis (UC) despite of a therapy with 5-aminosalicylates and steroids represent a clinical challenge, since the alternatives in medical therapy are considerably fewer compared to those for patients with active C
Methotrexate response in treatment of UC ARRA
Three of the critical issues in modern cancer research and evolutionary theory include (a) an understanding of the progression of mutations over time, (b) an identification of the cell of origin of these tumors, (c) and the differential respons
EVOLUTIONARY DYNAMICS OF BRAIN, LUNG, AND HEMATOPOIETIC TUMORS
This grant will increase Maryland’s Primary Care Office ability to coordinate activities toward strengthening the primary care workforce through the following activities:     1. Implement a PCO newsletter 2. Draft, finalize and distribute a P
Our studies will elucidate molecular mechanisms that control cell division in osteoblasts, as a component of normal development and maintenance of bone tissue. Our studies focus on a transcription factor that is critical for bone formation in h
Bone Cell Growth Regulation by Runx2/Cbfa1
The long-term objective of the proposed research is to determine the effects of age on the susceptibility of the retinal pigment epithelium (RPE) to oxidative stress. Oxidative stress to the RPE is believed to decrease the support that the RPE
Enzymes of the ubiquitin proteasome system (UPS) and their substrates are increasingly implicated in fundamental cellular processes, including cell proliferation, differentiation, transcriptional regulation, and stress response, amongst many ot
Global Approches to Protein Ubiquitylation
?1-adrenergic receptors (?1ARs) generally do not couple to the adenylyl cyclase inhibitory heterotrimeric G protein, Gi, however, data in cultured cells indicate that phosphorylation of ?1ARs by GRK5 can allow for Gi-coupling due to GRK5 action
Transgenic Targeting of Vascular G Protein Signaling
Funds to purchase Pediatric Influenza Vaccine
Purchase of Adult Vaccines - Havrix, Engerix B, Twinrix & Boostrix
To supply vaccines for CDC's adult vaccine contract
Herpes and Zoster Study (part 2) Herpes Trends and Risk Factor Effectiveness.  Special Study ? not R&D. Study Designed to obtain data and trend herpes zoster incidence to monitor the impact of the zoster vaccine program.
The COPS Hiring Recovery Program (CHRP) provides funding directly to law enforcement agencies to hire and/or rehire career law enforcement officers in an effort to create and preserve jobs, increase their community policing capacity and crime p
Pavement & Rehabilitation, North VI, 2009
2009 Traffic Signal Improvements (9 Locations)
Interstate Bridge Maintenance, Christina (PE)
IH 10 Fr. FM 659 (ZARAGOZA RD.) To. 0.19 MILES WEST OF EASTLAKE BLVD; FLYOVERS FROM IH 10 TO LP 375 FOR ALL DIRECTIONAL TRAFFIC MOVEMENTS
The immune system is a relevant target for analyzing how cells interpret the myriad of signals they receive through their surface receptors to make decisions regarding their fate and/or functional responses. Alterations in these processes contr
Role of PTPRkappa in Lck Regulation During T cell Development
The goal of our proposal is to understand how alphavirus replicon particles (nVRPs) function as adjuvants. nVRPs stimulate a protective systemic and mucosal immune response when co-delivered with a target antigen even when delivered at a non-mu
ROLE OF INNATE IMMUNITY IN RESPONDING TO AN ALPHAVIRUS-BASED ADJUVANT
The specific aims of this proposal are: 1) To characterize the metal regulators AdcR and SczA. AdcR regulates the expression of a zinc uptake system in S. pneumoniae that is necessary for virulence and adhesion. I will elucidate using in vivo g
Evaluation of zinc homeostasis mechanisms in Streptococcus pneumoniae
As one of the first cells to contact HIV, dendritic cells (DCs) are believed to play a central role in establishing infection and subsequent viral dissemination. All currently defined interactions between HIV and DCs rely upon the HIV Env. Prev
Characterization of a Novel Dendritic Cell Receptor for HIV-1
The general objective of this project is to upgrade cage wash support service equipment for two satellite buildings housing laboratory animals in the Division of Laboratory Animal Resources at Stony Brook University (SBU). The University has bo
ARRA: Cagewash Service Support Equipment
facility to be enclosed to improve and maintain a high level of cage sanitation.
Building K2 Cagewash Facility Renovation
The long-term goal of this project is to provide high-quality animal care and housing that enhances the productivity of Oregon Health & Science University (OHSU)'s PHS-funded researchers. This proposal has two specific aims: 1) to expand the ca
MOUSE CAGING FOR THE OHSU BIOMEDICAL RESEARCH BUILDING (BRB
The purpose of this award is to expand access to needed primary health care services specifically by expanding services at existing health center sites in an underserved area or for an underserved population.     The project will have a signifi
Grant Name:Increase Demand for Services. Purpose: To increase access and availability of SMC's primary health care services. Goals: 1).To hire a physician and/or locum so that SMC has more physician time available to patients who are in need of
INCREASE TO PROVIDER STAFFING BY HIRING A FULL TIME FAMILY MEDICINE MID LEVEL PROVIDER TO PROVIDE OPEN ACCESS PATIENT CARE AT THE MAIN FACILITY IN ORDER TO PROVIDE ADDITIONAL PATIENT CARE ACCESS FOR BOTH ESTABLISHED AND NEW PATIENTS.
ARRA INCREASE SERVICES TO HEALTH CENTERS
Increased Service Demand in Health Centers
GMHC Increased Service to Health Centers
STEDMAN - WADE HEALTH SERVICES, INC., THE
Grant Name: Increase Demand for Services - HABCS12211  Purpose: To hire a third provider. Having two providers was not enough for the patient load at Wade Family Medical Center.  Stedman-Wade Health Services, Inc. is the only FQHC in the servic
HARLEM UNITED: COMMUNITY AIDS CENTER, INC.
Harlem United is proposing a project plan consisting of three inter-related components. Increased Hours of Operation - The first component is an expansion of dental clinic hours at Harlem United?s 123-125 West 124th Street site in Central Harle
ARRA Increase Services to Health Centers.
The longstanding commitment of UC Irvine's Family Health Centers (FHC) to its community derives from its mission as a community health center.  Since the beginning of its operation, FHC has always developed and maintained a core group of qualit
The proposed National Center on Minority Health and Health Disparities Center of Excellence (NCMHD COE)for the Study of Health Disparities in Rural and Ethnic Underserved Populations at the University of California, Merced (UC Merced)will devel
Center of Excellence on Health Disparities in the Ethnic and Rural Underserved
This proposal will support a novel partnership between a community-based organization (Arthur Ashe Institute of Urban Health), a government agency (Office of the Brooklyn Borough President) and an academic research institution (Downstate Medic
The Gladstone Institute of Neurological Disease (GIND) at he University of California, San Francisco (UCSF) uses an interdisciplinary teann approach to the investigation of neurodegenerative disorders. Alzheimer's disease (AD) is the main cause
NOVEL THERAPEUTIC APPROACHES TO ALZHEIMER'S DISEASE
The work to be conducted by this newly hired faculty member will directly address one of the most serious public health problems in the US, alcohol-related illness and injury. Behavioral therapies have been shown to be effective in controlled l
MOVING ALCOHOLISM TREATMENT BEHAVIORAL THERAPIES FROM THE LAB TO THE COMMUNITY
The overall aim of this P30 proposal to the National Institute of Aging is to enhance the capability of the University of Chicago to perform research on how the social context of older persons - whether personal socioeconomic and health factors
NEW FACULTY RECRUITMENT FOR INTERDISCIPLINARY RESEARCH ON AGING
Completing the Aims of this P30 Neurodegenerative Disease Core Center will build further the multidisciplinary community of neurodegenerative disease researchers at PENN by recruiting two new faculty members whose expertise complements existing
NIA Core Center to Build Neurodegenerative Disease Research Faculty At Penn
This proposal seeks to support a research program in the area of tissue engineering in the musculoskeletal sciences. It is aimed at enriching the infrastructure of a translational research partnership at the University of Rochester. The partner
TISSUE ENGINEERING AND THERAPEUTIC ADVANCES IN MUSCULOSKELETAL MEDICINE
This Faculty Development Research Core will recruit Dr. Julius Birnbaum and Dr. Ami Shah to the tenure track faculty as Assistant Professors in the Division of Rheumatology at Johns Hopkins University. The Division of Rheumatology at Johns Hopk
DEFINING MECHANISMS OF DISTINCT TISSUE DAMAGE IN DIFFERENT RHEUMATIC SYNDROMES
Understanding the basis of addiction requires insights at every level of neuroscience from defining the initial drug responses, the adaptive changes in cellular function resulting from drug exposure, the learning and memory plasticity changes a
New Faculty Search for Functional Proteomic Approaches to Drug Abuse
This application is from the School of Dentistry (SOD) at the University of Alabama at Birmingham (UAB) in response to the NIDCR RFA-OD-09-005 titled Recovery Act Limited Competition: Supporting New Faculty Recruitment to Enhance Research Resou
UAB SOD'S INSTITUTE OF ORAL HEALTH RESEARCH ENHANCEMENT VIA FACULTY RECRUITMENT
This is a P30 application to establish a Center in Craniofacial Bone Biology at New York University College of Dentistry (NYUCD). This will advance research into understanding important disease processes such as cleft palate and lead to strateg
We propose to hire a new Assistant Professor in the area of Stem Cell Research, with a specific interest in either Neurological Stem Cell Biology or Mesesenchymal Stem cell Biology as an Investigator in the San Antonio Institute for Cellular an
Advances in molecular medicine, genomics, proteomics and bioinformatics have enhanced our understanding of inter-individual variability in susceptibility to disease, in expression of disease, and in beneficial and adverse responses to therapies
During the past quarter, we have made excellent progress in establishing Dr. Anwarul Ferdous as an independent investigator in the Division of Cardiology here at UT Southwestern Medical Center.  He is swiftly establishing an independent program
Functional Genomics of Complex Vascular Disease - ARRA Stimulus New Faculty
This application is seeking support for a new Assistant Professor in the Center for Regenerative Medicine (CRM), at the Massachusetts General Hospital (MGH), Harvard Medical School. This individual will be located in recently completed laborato
Center for Regenerative Medicine (CRM) Support for New Faculty Member
T.his is a NIH P30 Biomedical Research Core Center Application (RFA-OD-09-005) on Fetal Programming in the Development of Obesity-induced Cardiovascular Diseases. The request is for support of salary and start-up costs for recruit of one new in
Biomedical Research Core Center (P30) on Fetal Programming
Protein disulfide isomerase in vascular diseases. The research interest of my laboratory is to understand the molecular mechanisms of vascular diseases such as thrombosis and inflammation. We are currently focusing on the role of protein disulf
Intravital Microscopy for Development and therapy of vascular diseases
DESCRIPTION (provided by applicant): Diabetes and obesity are major risk factors for cardiovascular disease, whose incidence is increasing in the United States at an alarming rate. There is an urgent need to increase our understanding of fundam
UNIVERSITY OF UTAH BIOMEDICAL RESEARCH CORE CENTER (P30) IN METABOLISM AND CVD
The overall purpose of the P30 award (RFA-OD-09-005) is to support the recruitment, laboratory startup, and career development of Viviana Ferreira, Ph.D., in the Department of Medical Microbiology and Immunology at the University of Toledo Coll
The role of complement proteins in cardiovascular disease
The overarching goal of this P30 application is to enhance research capacity in the understanding and treatment of cardiovascular, pulmonary, and blood diseases, and other biomedical and translational research areas through the development of s
Faculty Recruitment and Core Resource Development in Stem Cell Biology
The goal of this proposal is to expand and strengthen a Core center within the Cardiovascular and Metabolic Disease Signature Research Program (CVMD) at the University of New Mexico Health Sciences Center (UNMHSC). The Core is the Vascular Biol
Building Core Programs in Cardiovascular and Metabolic Disease
Molecular and Cellular Mechanisms Underlying Function and Dysfunction of Neural Circuits. The overall purpose of this award is to recruit two junior faculty members (principal investigators) to a new Program in Neural Circuits and Behavior. Fun
MOLECULAR AND CELLULAR MECHANISMS UNDERLYING FUNCTION AND DYSFUNCTION OF NEURAL C
This program addresses the synergistic interactions of combustion-generated organic pollutants and particles that increase their chemical and biological activity. Program goals include: 1) understand the relationships between the origin, mechan
Health Impacts of Toxic Combustion By-Products
An interdisciplinary program for systems genomics of complex behaviors-ARRA 1P50MH090338      For this award, we propose a highly ambitious yet realistically attainable goal: to align existing expertise at UNC-Chapel Hill into a CEGS called CIS
An interdisciplinary program for systems genomics of complex behaviors-ARRA
The theoretical framework of this study maintains that the main paradigm guiding the sociological study of the impact of psychosocial stressors on distress and drinking outcomes has primarily operationalized micro-level social stressors. By con
Macro level Stressors Terrorism and Drinking Outcomes
Award Description* DESCRIPTION (provided by applicant): Zinc is now believed to be an intracellular second messenger. It is hepatoprotective against various toxins and counteracts the oxidative stress elicited by compounds that have been linked
THE ROLE OF ZINC IN THE CONTROL OF HEPATIC OXIDATIVE STRESS
Protein secretion is among¿ the most important functions of hepatocytes. Defects in the secretory pathway can have serious consequences~ For instance, patients with congenital disorders of glycosylation in which secreted proteins are not prope
UNDERSTANDING FATTY LIVER DISEASE USING THE ZEBRAFISH MUTANT, FOIE GRAS
Chronic alcoholism increases the incidence and severity of respiratory diseases and infections. Indeed, alcoholics compared to non-alcoholic individuals have increased mortality and morbidity during bacterialpneumonias. While much is known abou
Specific Aim: Examine cellular energetics and maintenance of the mitochondrial membrane potential (MMP) in ATP61 mutants.    A. Examine energetics as a function of age in ATP61 mutants and controls. Young ATP61 mutants did NOT exhibit an energe
Mitochondrial Dysfunction and Progressive Encephalomyopathies
The goal of this project is to develop a passive immunization approach to prevent humans accidentally exposed to prions from developing a universally fatal disease. Prion diseases (prionoses) are transmissible, invariably fatal, neurodegenerati
Therapeutic Monoclonal Antibodies for Human Prion Diseases
The present proposal seeks to determine the individual and interactive effects of estrogen and serotonin on cognitive processing and brain activation through the addition of functional magnetic resonance imaging (fMRI) to the paradigm of trypto
Interaction of Estrogen and Serotonin in Modulating Brain Activation in Menopause
The project will develop a standardized Impairment Activity Staging System which specifies the medical impairment perceived by an individual or close proxy to be limiting his or her ability to perform daily activities,   and then stages patient
DESCRIPTION (provided by applicant): Alzheimer's disease (AD) has been linked to deposition of beta-amyloid (Ab) as amyloid plaques in the brain. Transgenic mice expressing the human Ab precursor protein (APP) produce high levels of Ab and deve
ARRA Transthyretin's Regulatory Role in Beta-Amyloid Aggregation and Toxicity
The objective of this study is to examine a model of health literacy coaching wherein Meals on Wheels (MOW) volunteers work with older adults to enhance patient communication skills.  While considerable progress marks the studying of written he
Meals on Wheels Volunteers as Health Literacy Coaches for Older Adults
High blood pressure is a strong, modifiable, independent risk factor for cardiovascular and renal disease, and was a primary or contributing cause of 11% of U.S. deaths in 2003 (American Heart Association, 2006).  The health burden of high bloo
The tick-borne infections, Lyme disease, Ehrlichiosis and Babesiosis, are significant public health problem in the U.S.  Once potential approach to the control of these diseases is to reduce carriage of the organisms in their wild-life reservoi
Development of a multivalent vaccine for mouse reservoirs of deer tick pathogens
Our data indicates that the Dectin-1 beta-glucan receptor is essential for defense against Aspergillus fumigatus, the etiological agent of invasive pulmonary aspergillosis (IPA). We will uncover innate anti-fungal mechanisms mediated by Dectin-
DECTIN 1 AND INVASIVE PULMONARY ASPERGILLOSIS
This proposal is in response to Notice Number NOT-OD-09-088 of the American Recovery and Reinvestment Act of 2009.  We request funding for the first two years of the revised grant application 1R01AI73718-01A2, with changes in scope approved by
MECHANISMS OF SIGNALING BY ACTIVATING RECEPTORS IN INNATE IMMUNE SYSTEMS CELLS
Aspergillus fumigatus and other species are increasingly the cause of morbidity and mortality among immunocompromised patients. Infections caused by these fungi are most prevalent in neutropenic patients with hematological malignancies. In the
Herpesviruses are major pathogens in human populations, causing disease in normal and immuno-compromised individuals. Double-stranded DNA (dsDNA) tailed bacterial viruses and herpesviruses share surprising similarities in capsid assembly and or
Structures of the portal vertex in dsDNA viruses and virus-infected cells
Bacterial flagellins are unusual microbial products that can be directly recognized by receptors of both the innate and adaptive immune system. Since flagellins initiate an innate immune response, they have the potential to function as molecula
Innate immune response to bacterial flagellins
Ebolaviruses and the closely related Marburgviruses continue to pose a lethal threat to human populations worldwide, especially given their potential use as bioweapons and the lack of effective vaccines or antiviral drugs to combat their pathog
ARRA Molecular Pathogenesis of Ebolavirus Infection
Influenza A virus causes annual epidemics and is potential threat for widespread pandemics. The genome of influenza A virus consists of eight segments of (-)RNA that are encapsidated in distinct double-helical structures called the ribonucleopr
THE INFLUENZA A VIRUS NUCLEOPROTEIN: STRUCTURE AND FUNCTION
Acute lung infection due to Pseudomonas aeruginosa is a common cause of death in hospitalized patients and the major cause of death in Cystic Fibrosis. A number of virulence factors have been proposed to lead to these poor outcomes. We wish to
Type II secretion system of P. aeruginosa in acute lung infection
Despite decades of work, the development of a successful HIV-1 vaccine has not yet been achieved. A better understanding of the requirements for HIV-1-specific lymphocyte activation, and the functions of activated lymphocytes, is therefore desi
HIV-ENVELOPE-SPECIFIC CD4+ T-CELL ACTIVATION AND FUNCTIONAL POTENTIALS
The long-term goal of this project is to understand the fundamental aspects of outer membrane vesicles produced by Gram-negative bacteria: How and why are they made? Outer membrane vesicles represent 0.1 to 1% of total outer membrane protein in
BIOGENESIS & FUNCTION OF BACTERIAL OUTER MEMBRANE VESICLES
CD4+ helper T cells specific for human immunodeficiency virus type 1 (HIV-1) are associated with control of viremia. Nevertheless, vaccines have not been effective thus far, at least partly because sequence variability and other structural feat
The purpose of this research is to define the structural basis for substrate and inhibitor specificities of lentivirus PRs through comparative studies of FIV and HIV PRs. ARRA funding has allowed the continuation of these studies to prepare and
Structural Basis for Drug Resistance in HIV and FIV PRs
Productive differentiation of thymic epithelium is critical for thymopoiesis and the establishment of self-tolerance. However, the differentiation program that forms the thymic environment is not well understood. Studies proposed here are inten
Differentiation programs of thymic epithelium
The overall goal of the proposed study is to determine how TonB-dependent and TonB-independent transport processes contribute to the ability of N. gonorrhoeae to grow in vitro and within clutured host cells. The specific aims of this proposal a
Iron acquisition mechanisms utilized by Neisseria gonorrhoeae
Various members of the Ras superfamily of small GTPases, which comprise over 200 proteins, are expressed selectively in all cells, where they perform a range of cellular functions. A well-studied subfamily is that of the Rho GTPases, with the t
Bone is a complex system whose critical function is to be sufficiently stiff and strong to support the physical forces associated with daily activities. Understanding how genetic and environmental variants compromise this function is critical t
FUNCTIONALITY AND FRACTURE SUSCEPTIBILITY OF CORTICOCANCELLOUS STRUCTURES
Loss of functional skeletal muscle due to congenital and acquired conditions, such as traumatic injury, tumor excision, etc., produces a physiological deficit for which there is still no effective clinical treatment. Tissue engineering of skele
Development of Bioengineered Skeletal Muscle for Functional Replacement in vivo
In 2008, over 66,000 people in the US will be diagnosed with Non-Hodgkin lymphoma (NHL), and over 19,000 will die of this cancer. Survival rates have only recently begun to improve, and the current 5-year survival rate is 66%. We have identifi
Molecular Epidemiology of non-Hodgkin Lymphoma Survival
Hypothesis is that a unique recombinant fusion protein derived from a cell-penetrating viral capsid shell can transport DNA intercalating drugs through a tiny nucleic acid carrier, and target such drugs to specific tumor cells causing tumor-spe
Protein-DNA Drug Carriers for Tumor Targeting
Solid tumors are complex tissues containing both neoplastic tumor cells and non-neoplastic cell types (e.g., vascular endothelial cells (EC), fibroblasts and macrophages) and the interactions between these cells can regulate tumor progression.
TWEAK-Fn14 Signaling in the Tumor Microenvironment
Goals: Our initial goal is to define the molecular pathways that regulate RKIP expression in prostate cancer. The long-term goal of this research is to better define the role of RKIP as a prostate cancer metastasis suppressor in vivo, and to id
RKIP regulation as a potential for tumor suppression
Genital infection with oncogenic types of human papillomavirus (HPV) is central to the development of invasive cervical cancer (ICC) and its immediate precursor, cervical intraepithelial neoplasia grades II-III (CIN2-3). However, infection with
INTRATYPIC VARIATION OF ONCOGENIC HPV TYPES AS A RISK FACTOR FOR CERVICAL NEOPLAS
DESCRIPTION (provided by applicant): The importance of the bone marrow in hematopoiesis has been well documented. However, the function of bone marrow in tumor T cell immunity is not well understood. Regulatory T cells (Tregs), dendritic cells
Regulatory T Cells and Tumor Bone Marrow Metastasis
Our research amis at using chemical synthesis to prepare four classes of anticancer natural products with great potential that have eluded study due to their scarcity in nature and the fact that no solution for their chemical synthesis exists.
Total Synthesis of Anti-Cancer Natural Products
Interaction of germline and somatic changes in PCa progression Abstract Recent successes in discovering germline variants associated with prostate cancer (PCa) risk is encouraging. However, whether these risk variants play role in PCa progressi
Interaction of germline and somatic changes in PCa progression
The goal of this project is to develop a software tool kit (based on the XIP application from Siemens corporation)  that will allow scientists to study prostate cancer by combining data from multiple imaging modalities (radiology and pathology)
SOFTWARE TO FACILITATE MULTIMODE, MULTISCALE FUSED DATA FOR PATHOLOGY AND RADIOLO
Meta!astatic melanoma is a deadly cancer, lacking an effective therapeutic strategy. It is widely acce:ted that dysfunctions of normal homeostatic regulation of melanoblasts result in neoplastic convirsion to melanomas, while the exact molecula
Role of Notch Signaling in Regulation of Autophagy in Melanoblast and Melanoma
The Northwest Regionalized Information System recognizes the need for local communities to combine services ehre taxpayer money can be saved.  As Erie County and Sandusky City are certified disparate both entities agree that Erie County will be
Northwest Regionalized Information System Phase II
FY 2009 Justice Assistance Grant Program - purchase in-car video and radar system; purchase of tactical vests and accessories; purchase of tactical equipment of Stop Sticks and Tasers.
FY 2009 Justice Assistance Grant Program
Office of the Comptroller of the Currency
edward Byrne memorial justice assistance grant program
The grant money recieved in this grant has helped the City of Dallas Police Department in improving equipment and techknowledgy
equipment and Technology improvement program
Sacred Spirits will open an Outreach Office in Moorhead, MN, strengthen sound financial management by hiring a Financial Specialist, capacity building and enhance it capability to secure and diversify funding by hiring an Organization Developme
Goal 1: Continue and expand statewide collaboration addressing policy and practice when responding to victims of domestic violence with children.  Objective 1: Coordinate cross disciplinary training to enhance and strengthen policy and practice
OVW Recovery Act Grant to State Sexual Assault and Domestic Violence Program
NEW MEXICO COALITION AGAINST DOMESTIC VIOLENCE
This award creates a legal position to strengthen New Mexico's statewide response to domestic violence.  The work included emphasizes improving the response of the legal system and creating more positions to serve victims of domestic violence.
Nevada's Recovery Act STOP supports communities in their efforts to hire and retain criminal justice and victim services personnel that respond to violent crimes against women as a way to develop and strengthen effective law enforcement, prosec
Nevada Recovery Act STOP Formula Program
Recovery Act STOP Violence Against Women Formula Grant Program. This award provides the opportunity to develop and strengthen effective responses to violence against women.
Recovery Act - OVW FY 09 STOP Violence Against Women Formula Grant
RHODE ISLAND DEPARTMENT OF PUBLIC SAFETY
Recovery Act Violence Against Women Formula Grants To retain and create jobs, in order to meet the needs of victims of domestic violence, sexual assault, dating violence and stalking.
This award provides the opportunity for recipients to develop and strengthen effective responses to violence against women. These funds will assist by preserving and creating jobs and promoting economic recovery.
The overarching purpose of all Violence Against Women (VAWA) Recovery Act funding is to hire and retain criminal justice and victim services personnel who respond to violent crimes against women, as well as support other strategies that create
Recovery Act STOP VAWA Formula Grant Program
STRONG HEARTED NATIVE WOMEN'S COALITION, INC
We are a nonprofit domestic violence and sexual assault coalition contracted on behalf of the Pauma Band of Mission Indians.   Increasing awareness of domestic violence and sexual assault against American Indian and Alaska Native Women Enhancin
Recovery Act-Grants to Indian Tribal Governments Program
The OVW Recovery Act - Grant to Indian Tribal Governments Program designed to fulfill the goals of Title IX including decreasing the number of violent crimes committed against Indian women, helping Indian tribes use their independent authority
Office on Violence Against Women, US Department of Justice Big Valley Rancheria Domestic Violence Program
1.Renovate the Maliseet Domestic Violence and Sexual Assault Program's Emergency Shelter to provide for better safety and security for the women and their children who temporarily reside there.  2.  Transitional Housing Assistance to provide su
Maliseet Domestic Violence and Sexual Assault Program
The Grant to Indian Tribal Governmnets Program was created in Title IX of the Violence Against Women Act of 2005. The Tribal Governments Program is designed to fulfill the three goals of Title IX: 1)to decrease the number of violent crimes comm
Office on Violence Against Women Recovery Act-Grants to Indian Tribal Governments Program
Obtaining and retaining homes for victims of domestic violence and sexual assult.
The home program:Obtaining and retaining homes for victims of domestic violence and sexual assult.
Hope House, Inc., a community domestic violence agency, has provided services for victims of domestic violence in eastern Jackson County, Missouri since 1983.  Hope House is a recipient of an OVW Recovery Act Transitional Housing Assistance Gra
Transitional Housing Program for Victims of Domestic/Dating Violence
DOMESTIC VIOLENCE INTERVENTION SERVICES, INC.
Sojourner's Inn Transitional Housing program is the name of our program.  The program is to provide victims of domestic violence, sexual assault, or stalking with transitional housing.  This program allows victims a place to live until they can
Sojourner's Inn Transitional Housing.  Provides transitional housing to victims of domestic violence, sexual assault, and stalking.
These OVWR/Recovery Act funds continue to support transitional housing services and related individualized support to help victims of domestic violence to transition into and retain permanent housing.  Specifically, grant funds continue to pay
The Womanspace, Inc. Transitional Housing Program provides assistance to victims of domestic violence, dating violence, sexual assault and stalking, to assist them in achieving safe, stable housing and the financial means to be self-sufficient.
The OVW Recovery Act Transitional Housing Assistance Grants Award for Victims of Domestic Violence, Dating Violence, Stalking, or Sexual Assault provides the opportunity to develop and strengthen effective responses to violence against women. T
A Safe Place: DVSC Bridge Housing Program for Victims of Domestic Violence and Their Dependent Children
FRIENDS OF WOMEN'S SUPPORTIVE SERVICES INC
The primary goal of this project is to increase housing opportunities and economic self-sufficiency for domestic and sexual violence survivors. Key objectives are to: 1) provide transitional housing assistance and follow up services to 50 survi
Georgia Mountain Women's Center will address the many obstacles victims of dometic violence encounter when moving towards self-sufficiency, both economically and in securing and maintaining affordable, permanent housing.  This project will prov
OVW Recovery Act Transitional Housing Assistance Grant for Victims of Domestic Violence, Dating Violence, Stalking, or Sexual Assault
WELLSPRING ALLIANCE FOR FAMILIES, INC, THE
Wellspring Recovery Act Transitional Housing Program to assist victims of domestic violence, sexual assault and/or stalking with housing assistance and other needs to move to independent living.
The Wellspring Recovery Act Transitional Housing Program
Women's Coalition Transitional Housing Program.  Over two years, the Women's Coalition of St. Croix (WCSC) will provide transitional housing services through the leasing of scattered site housing units to approximately twenty (20) women and the
Transitional Housing for Victims of Domestic Violence, Dating Violence, Stalking, or Sexual Assault
The project will provide up to twenty four months of transitional housing and voluntary supportive services with the goal of assisting homeless women and children, fleeing domestic violence, dating violence, stalking or sexual assault, to achie
Recovery Act STOP Violence Against Women Formula Grant Program
This project provides housing services, transitional housing, support and crisis intervention services and counseling for victims of sexual assault, domestic violence, dating violence and stalking.
Clackamas Women's Services Transitional Housing Program Beyond Shelter Housing Initiative
The Shelter House Bridgeway (SHBC) Transitional Housing Program will support victims of domestic violence, dating violence, stalking, and sexual assault by providing safe, secure housing with a wide range of flexible supportive services that wi
DOMESTIC AND SEXUAL VIOLENCE SERVICES OF CARBON COUNTY (DSVS)
Provide transitional housing and support services designed to help victims secure permanent housing and integrate into the community, including employment counseling, job training, economic advocacy, transportation, counseling and child care se
Enhancing Transitional Housing and Job Training/Economic Advocacy in Southeast Montana
OVW Recovery Act Transitional Housing Assistance Grants for Victims of Domestic Violence, Dating Violence, Stalking, or Sexual Assault
Young Women's Christian Association of Spokane Alternatives to Domestic Violence Programs
The Transitional Housing Assistance Program grant must be used to support programs that:  (a) provide transitional housing, including funding for the operating expenses of newly developed or existing transitional housing; (b) provide short-term
OVW Recovery Act Transitional Housing Assistance Grants for Victims of Domestic Violence, Dating Violence, Stalking or Sexual Assault
The purpose of the Transitional Housing Recovery Grant is to provide supportive services to victims of domestic violence, dating violence  Programs that provide support services designed to enable individuals who are fleeing domestic violence,
DellaGill/Joyce H. William Center Transitional Housing Program
The Prison Rape Elimination Act (PREA) was signed into law on September 4, 2003, to address the problem of prison rape throughout the nation.  PREA supports the elimination, reduction, and prevention of sexual assault within federal, state and
OVW Recovery Act - Grants to State Sexual Assault and Domestic Violence Coalition Programs
NEW YORK STATE COALITION AGAINST SEXUAL ASSAULT, INC.
The availability of OVW Recovery Act Grant funds will allow NYSCASA to preserve/retain one staff member.  This Membership Program Services staff member, the Member Program Specialist, is a professional level, degreed individual with knowledge o
To expand the coalition's support to rape crisis programs, underserved populations and increasing number of participants at trainings to end sexual assault and aid victims and survivors.
Provide opportunity to develop and strenghten effective responses to violence against women
NORTHERN MARIANAS COALITION AGAINST DOMESTIC AND SEXUAL VIOLENCE
The Northern Marianas Coalition Against Domestic & Sexual Violence (NMCADSV) submitted this proposal to build the CNMI?s capacity in serving victims of sexual assault by being a catalyst for collaboration and coordination between service provid
Northern Marianas Coalition Against Domestic & Sexual Violence - Recovery Act
ALASKA NETWORK ON DOMESTIC VIOLENCE & SEXUAL ASSULT INC
1.Expand the technological capacity of the coalition by providing a streamlined, efficient information technology network of communication that is confidential, cost-efficient and user friendly. 2. Provide a strategic planner to facilitate coal
Creating jobs and promoting economic recovery at ANDVSA
VIRGINIA SEXUAL AND DOMESTIC VIOLENCE ACTION ALLIANCE, THE
State coalition grant used to develop and strengthen effective responses to violence against women in Virginia.  It also supports the coalition's efforts in promoting economic recovery, and preserving and creating jobs that coordinate victim se
Virginia Sexual and Domestic Violence Action Alliance
This award allowed the West Warwick Police Department to purchase vital assets that would allow the agency to further public safety within our community. Four (4) Ford Victoria cruisers were purchased. The 2009-2010 budget would not have made t
West Warwick Police Department Fleet/Communications Upgrade
Child Care Development Fund Supplemental funding for CCDF to provide financial assistance for families utilizing childcare. This award was also used to improve quality with enhanced curriculum and supplies.
CALIFORNIA RURAL INDIAN HEALTH BOARD, INC.
ARRA Supplemental Fund for Child Care and Development Fund program.  The funds are to be used to supplement the need for child care subsidies.
ARRA Supplimental Funding for the Child Care and Development Fund (CCDF).  To provide child care financial assistance to low-income working families and fund activities to improve the quality of child care.
The Child Care Development Block Grant provides funds to expand services to additional children and families facing difficult economic circumstances and to support the health and well-being of children.
American Recovery and Reinvestment Act Port Security Grant Program (ARRA PSGP)
American Recovery and Reivestment Act Port Security Grant Program (PSGP)
Pipeline Transportation of Refined Petroleum Products
WILDLIFE AND FISHERIES, LOUISIANA DEPARTMENT OF
Hepatocellular carcinoma (HCC) is a leading cause of cancer-related deaths. Although many cases of HCC are induced by chronic alcohol abuse or environmental toxins, approximately 80% are caused by infection with either hepatitis B or hepatitis
ROLES FOR RCK/DDX6 IN HEPATITIS C VIRUS PATHOGENESIS ANDHEPATOCELLULAR CARCINOMA
The spread of HIV and sexually transmitted diseases (STD) remains one of the most serious threats to general adolescent health.  The severity of the STD/HIV threat increases significantly for adolescents when the intercorrelated use of illicit
Web-Based Substance Abuse STD/HIV Prevention
More than 850,000 Americans are currently living with AIDS and an estimated 40,000 continue to contract HIV each year (CDC, 2004). Minority individuals living in urban and poverty-stricken areas who engage in injection heroin use are particular
NOVEL INTERVENTION FOR DRUG USE AND HIV RISK AMONG ANXIETY SENSITIVE HEROIN USERS
The revised scope of work focuses on the SSDP longitudinal study, and NYS is not included. The revision permits the accomplishment of the first three aims of the originally proposed five year study. In addition, this support will place the stud
Gene-Environment Interplay in the Development of Drug Abuse and Comorbid Problems
Neural Mechanisms of Heroin-induced Conditioned Immunomodulation Our laboratory was the first to demonstrate that the detrimental health consequences of opiates can be conditioned to environmental stimuli predictive of drug administration. The
Neural Mechanisms of Heroin-induced Conditioned Immunomodulation
The primary purpose of this research is to develop and evaluate the short-term efficacy of an innovative multiple behavior screening, brief intervention and referral to treatment (MB-SBIRT) model using social and self-image to simultaneously li
Multiple Behavior SBIRT Model of Drug Abuse Among Emerging Adults in Primary Care
A scientific search for therapeutically useful compounds in combating psychostimulant abuse and addiction has been in progress for decades, with no clinically available agents to date. Rational, brain receptor protein-guided design of novel ant
DOPAMINE TRANSPORTER STRUCTURE AND FUNCTION
Marijuana is the most commonly used illicit substance among adolescents in the United States.  Marijuana has profound effects on cognition, memory, and psychomotor skills.  Optimal performance in these domains is critical for adolescents to ach
A Controlled Trial of N-Acetylcysteine (NAC) in Cannabis-Dependent Adolescents
Cannabis use disorder (CUD) occurs frequently in patients with schizophrenia (SCZ) and worsens the course of this severe psychiatric disorder. Treatments available for these 'dual diagnosis' patients are inadequate. Most of the antipsychotic dr
Cannabis and Schizophrenia: Self-Medication and Agonist Treatment?
An understanding of the morphogenesis and operation of hair cells requires identification of the genes expressed in these cells and of the functions of the cognate proteins. As an initial step towards this goal, we have used DNA-microarray tech
Elucidating the Molecular Mechanisms that Shape the Hair
This proposal is analyzing the interactions between azole antifungal drugs and fungal cells by studying both the growth parameters (biochemical and microbiological), and the gene expression patterns of susceptible and resistant isolates. The re
AIDS Related Candidiasis: Dynamic Expression of Drug Resistant Genes
The management of inflammatory pain represents a major scientific and health care challenge and many currently used analgesics provide inadequate pain relief. A mechanistic-based approach to pain management might contribute to the development o
INTERACTIONS OF TRPV1 AND TRPA1 AND INFLAMMATORY PAIN
An association between infection and suboptimal regenerative outcomes has often been described in the periodontal and oral surgical literature. It is also increasingly recognized that low-level bacterial contamination can play a role in 'asepti
Devices for Treating Inflammatory Bone Loss in an Oral Environment
The Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) is a multifunctional protein that transports chloride across the apical plasma membrane of epithelial cells. CFTR also regulates ion transport by other proteins, such as the Epithel
REGULATORY INTERACTIONS OF CFTR AND ENAC
DESCRIPTION: Current methods for measuring dietary intake in free-living people typically result in an average under- estimation of energy intake (EI) of 10-50%. Data are suggestive, but not conclusive, that EI underreporting is specific to foo
Biomarkers of Dietary Variables Commonly Misreported
Characterization of TGR5-D2-WSB1 pathway - testing the hypothesis that TGR5 and WSB1 regulation of D2 activity and thyroid hormone activation is a key pathway involved in the control of energy homeostasis. Generating genetically engineered mous
CHARACTERIZATION OF TGR5-D2-WSB1 SIGNALING IN METABOLIC HOMEOSTASIS IN VIVO
Mounting evidence indicates that alterations in chromatin structure and function induce specific and significant changes in gene expression. Histone deacetylases (HDACs) are an evolutionarily conserved class of enzymes which remove acetyl group
Histone Deacetylases & Kidney Development
While our knowledge on early liver development increased considerably in the past decade, much remains to be learned on how the distinct regulators of liver organogenesis operate at the molecular level. This information is necessary not only to
ROLE OF PROX1 IN LIVER DEVELOPMENT AND LIVER HOMEOSTASIS
With the increase in obesity and diabetes, other chronic diseases are also increasing. Nonalcoholic fatty liver disease (NAFLD) is one such disease that has potentially enormous public health consequences. NAFLD is a leading cause of chronic li
EPIDEMIOLOGY OF ULTRASOUND-DEFINED NAFLD IN THE GENERAL U.S. POPULATION
Given that only organs in pristine condition are transplantable, orthotopic transplantation will always remain a limited pool. A more elegant, long-term solution is using stem cells to develop tissue-engineered replacements. However, while many
DESCRIPTION: Chronic non-bacterial inflammation of the prostate is associated with multiple prostate diseases including chronic prostatitis-chronic pelvic pain syndrome (CP-CPPS), benign prostatic hyperplasia (BPH), and prostate cancer. CP-CPPS
Initiation and Regulation of Chronic Autoimmune Prostate Inflammation
We hypothesize that a profound deficiency of nutritional vitamin D (25-hydroxyvitamin D; 25D) in end-stage renal disease (ESRD) leads to an altered immune response, predisposing to early morbidity and mortality from infection, the second-leadin
Ergocalciferol in ESRD Efficacy Safety and Biology
DESCRIPTION (provided by applicant): Particulate air pollutants (particulate matter; PM) are ubiquitous in the environment. Increases in human respiratory and cardiovascular dysfunction, disease, and mortality have been linked to both short- an
There has been explosive growth in engineering disciplines based on nanomaterials. Their unique physical properties compared to larger microparticles both enable these novel engineering applications as well as raise questions related to their i
Comparative In Vivo Biodistribution of Characterized Manufactured Nanomaterials
DESCRIPTION (provided by applicant): The proposed research investigates a representation of spatial layout that serves to guide action in the absence of direct perceptual support. We call this representation a 'spatial image.' Humans can percei
Multimodally encoded spatial images in sighted and blind
New approaches to lower intraocular pressure, a significant risk factor for the progression of glaucoma, will be investigated.  Gene therapy approaches will be utilized to lower IOP by enhancing outflow via the uveoscleral pathway. One of the c
ARRA Aqueous humor dynamics studies in vivo and in vitro
This award addresses critically important unresolved issues concerning the antioxidant capacities of vertebrate photoreceptor cells and inner retinal neurons. A common factor in the loss of photoreceptor cells appears to be reactive oxygen spec
Photoreceptor Cell Vulnerability and Glutathione Status
Choroidal neovascularization (CNV) is a severe complication of age-related macular degeneration (AMD). Human genetic studies have recently revealed significant association of the very low-density lipoprotein receptor (VLDLR) and a wnt co-recept
The WNT signaling pathway in choroidal neovascularization
There are now almost 200 genes and chromosomal loci which have been identified as causing some form of inherited retinal degeneration. Irrespective of the primary mutation or cause, all of these diseases are thought to share a major common even
Prevention of Inherited Retinal Diseases by Therapeutic Rare Earth Nanoparticles
Despite the major public health impact, the etiologies of refractive errors generally and myopia in particular are poorly understood. We are conducting an innovative approach to evaluate altered gene expression in eyes of chicks developing refr
MOLECULAR CHARACTERIZATION OF CHICK RETINA DURING REFRACTIVE DEVELOPMENT
Note:  This project is being supported with funds from the American Recovery and Reinvestment Act, which resulted in a reduction in the research aims and scope.  A revised abstract has been provided. Age-related macular degeneration (AMD) is a
THE APOE TR MOUSE: A MODEL FOR ELUCIDATING PATHOGENIC MECHANISMS OF AMD
The broad objective of this project is to prevent degeneration of cone photoreceptors, which are essential for human color vision.  In a disease such as Leber Congenital Amaurosis (LCA), the levels of the native chromophore of visual pigments,
Cone Opsin-Ligand Interactions and Photoreceptor Health
Eye Diseases, Blindness & Vision Impairments
DiffeProper transgene expression is essential to achieve therapeutic effect and ensure safety in many gene therapy strategies. Current regulation systems for controlling transgene expression typically require use of a special promoter and co-de
Differential regulation of multiple transgenes for treatment of eye disease - AR
The project will study the DNA unwinding element binding protein DUE-B, with the goal of determining the mechanism by which the binding of DUE-B to replication origins is controlled, and by which DUE-B regulates the binding of other replication
The Role of the DNA Unwinding Element Binding Protein, DUE-B, in DNA Replication
Extreme thermoacidophily (growth ¡Ý 60¡ãC, pH ¡Ü 3) is a remarkable growth physiology exhibited by certain members of the Crenarchaeota and Euryarchaeota, the major archaeal phyla. Interesting features of microorganisms in this group incl
Metabolic Engineering Studies of Extreme Thermoacidophily
The Golgi is the organelle responsible for the posttranslational modification of proteins. Glycosylation, the most prominent posttranslational modification, results in the biosynthesis of glycoproteins and proteoglycans (PGs). Glycosylation is
An Artificial Golgi:  Controlled GAG Synthesis and Screening
Restoration of functional grasping would be of great benefit to people with hemiparesis post stroke. While task-specific training may be the best way to promote functional recovery, implementing such training for grasping is difficult because t
EFFECTS OF MOVEMENT CONTEXT ON HEMIPARETIC GRASPING EARLY AFTER STROKE
Novel Approaches to Screening for Inflicted Childhood Neurotrauma  Inflicted childhood neurotrauma (ICN) - traumatic brain injury due to child abuse - is the leading cause of death from traumatic brain injury (TBI) in children less than 2 yrs o
Novel Approaches to Screening for Inflicted Childhood Neurotrauma
ARRA - Socioeconomic Disparities in Young Adult Health  In the United States, large and persistent health disparities exist across the life course.  Reducing these disparities is a top priority for policymakers and the public.  Of particular im
ARRA - Socioeconomic Disparities in Young Adult Health
WOMEN & INFANTS HOSPITAL OF RHODE ISLAND
The purpose of this supplement is to provide funding support for students seeking careers in heath science related research with a particular interest in neurodevelopment and cellular and molecular biological mechanisms of perinatal Hypoxic-isc
Cytokines and the Blood Brain Barrier in the Ovine Fetus: Administrative supplement providing summer research experience for students
Women and Infants' Hospital, Kilguss Research Center
Developing germ cells must be in intimate contact with Sertoli cells for the successful completion of spermatogenesis. This cellular interaction is facilitated by specialized actin-based adherens junctional complexes known as ectoplasmic specia
CATENINS: A ROLE IN SPERTMATOGENESIS AND SPERM MATURATION
Polycystic ovary syndrome (PCOS) is the most common endocrine disorder of premenopausal women, affecting ~7% of this population. It has major reproductive and metabolic morbidities across the lifespan, including markedly increased prevalence ra
Genome-Wide Association Scan of Polycystic Ovary Syndrome Phenotypes
Follicular development and differentiation, key to female reproduction, are sequential events that are tightly regulated by balanced cell proliferation, survival and cell death. Previously we reported the prohibitins, PHB1 and REA, as important
Mechanism of Action of Prohibition in Ovarian Cell Function
For the hundreds of thousands whose lives have been saved by antiretroviral therapy (ART), scale-up has been a success. There is an urgent need, however, to better understand how access to ART shapes risk and protective behaviors. Moreover, gro
Life Projects and Antiretroviral Therapy: The Social Impacts of Scale-up
Maternal cortisol concentrations are normally increased by 2-3 fold in pregnancy. Maternal cortisol levels appear to affect fetal skeletal and visceral growth. Our previous data show reduced growth in fetuses of ewes with either increased or de
EFFECTS OF MATERNAL CORTISOL ON FETAL AND NEONATAL GROWTH AND METABOLISM
SWI/SNF & Yolk Sac Development The mammalian yolk sac and placenta provide an important nutritive role in the early postimplantation embryo. Development of these tissues is highly sensitive to the regulation of temporal and spatial expression o
Sexual reproduction provides ample opportunity for pairwise interactions between the genotypes of mating pairs. One consequence of processes that are rife with male x female interactions is that evolution may fail to optimize functions for eith
DROSOPHILA GENES CAUSING MALE X FEMALE INTERACTION IN REPRODUCTION
Cerebral hypoxia-ischemia during the perinatal period is the single most important cause of acute newborn mortality and chronic disability. Despite our increasing understanding of the mechanisms of neuronal injury, an effective clinical therapy
Novel Mechanisms of Neonatal hypoxic-Ischemic Brain Injury and Repair
The long-term aim of this research is to understand how human genetic variation influences drug toxicity.  In this ARRA request, we will continue our efforts to elucidate mechanisms underlying adverse drug reactions to oral anticoagulants, spec
Warfarin Pharmacogenetics in Pediatric Patients
Mucopolysaccharidosis I (MPS I) and MPS VII are lysosomal storage diseases in which glycosaminoglycans (GAG) accumulate due to deficient activity in alpha-L-iduronidase and beta-glucuronidase, respectively.  This results in multisystemic diseas
PATHOGENESIS OF DISEASE IN MUCOPOLYSACCHARIDOSIS I AND VII
The most significant determinant of educational and clinical impairment in school-age children with autism spectrum disorders (ASD) is the frequent co-occurrence of hyperactivity and inattention symptoms. In response, clinicians treating ASD ar
Neural Dissection of Hyperactivity/Inattention in Autism
The expected broad impact of the proposed activity are: (A) the theoretical models being developed would provide much needed guidance in the experimental efforts to develop a viable ultra rapid DNA sequencing technology based on the nanapore id
Mathematical Modeling of the Voltage Driven Translocation of Polyelectrolytes Through Nanopores
Human ether a go-go-related gene 1a (HERG1a, Kv11.1) K+ channels play a critical role in maintaining the fundamental cardiac rhythm. The significance of HERG1a channels is that they are the central component of the rapid delayed-rectifier K+ ch
Molecular Physiology of HERG (KCNH2) Potassium Channels
The leading causes of Type 2 diabetes and prediabetes are being overweight or obese and being sedentary. Diabetes and prediabetes have adverse effects on parameters of cardiac and peripheral vascular structure and function that precede clinical
NORTHERN CALIFORNIA INSTITUTE FOR RESEARCH AND EDUCATION, INC.
Heart failure has reached epidemic proportions in the United States and is responsible for nearly 500,000 deaths each year. The majority of heart failure cases is now the result of infarction-induced left ventricular (LV) remodeling. The lack o
Epidemiology of Depression and Heart Failure in Aging
In this proposal, we describe a new pathway signaling PMN influx and damage to the airways that may play a role as an initiator or cofactor for chronic obstructive pulmonary disease (COPD).  Specifically, chemical or enzymatic breakdown of coll
THERAPEUTICS FOR CHRONIC LUNG DISEASE ANTAGONISTS OF PGP CHEMOKINES AND CXCR
Racial disparities exist in cardiovascular disease (CVD), with blacks having more prevalent and severe CVD compared to whites, independent of race-related differences in CVD risk factors. Despite having higher rates of CVD, blacks are less like
Racial Differences in Atherosclerosis, Plaque Vulnerability, and CVD
The lung is constantly under a pre-existing tensile stress or prestress generated by transpulmonary pressure which changes cyclically with breathing. This prestress is transmitted through the alveolar walls to the extracellular matrix (ECM) in
EFFECTS OF MECHANICAL FORCES ON LUNG INJURY AND REPAIR
Sepsis, a maladaptive response to infection, is a common and lethal syndrome. Many studies have examined the activities of leukocytes and endothelial cells in sepsis or in surrogate models, but the role of platelets in the disease process has r
NOVEL THROMBOTIC AND INFLAMMATORY ACTIVITIES IN PLATELETS IN SEPSIS
Diabetes mellitus (DM) is of major epidemiological importance, accounting for a high incidence of heart failure in these patients. Hyperglycemia, as an independent risk factor, directly causes cardiac damage and leads to diabetic cardiomyopathy
ROLE OF RETINOID MEDIATED SIGNALING IN DIABETES AND CARDIAC REMODELING
Telomeres, the DNA TTAGGG repeat sequences at the ends of eukaryotic chromosomes, are stabilized by telomerase to serve as protective capping and to prevent degradation. Stem cells constitutively overexpress the catalytic core telomerase revers
Telomerase in Inflammation and Atherosclerosis
Short sleep duration (less than 6 hours/night) is associated with a higher prevalence and incidence of hypertension, diabetes, and overweight/obesity, all of which can contribute to coronary heart disease. Pathophysiologic mechanisms that could
Autonomic, Endothelial, and Inflammatory Correlates of Sleep Duration
Primary lymphedema is the clinical expression of defects in lymphatic development and function. Three genes have been shown to cause primary lymphedema, VEGFR3, FOXC2 and SOX18. Mutations in these genes account for only a fraction (~1/3) of all
HGF and MET Mutations in Primary Lymphadema
According to the World Health Organization, 15 million people worldwide suffer a stroke every year. Of these, 5 million die and another 5 million are left permanently disabled, placing a heavy burden on families, communities, and governments. W
A GENOME-WIDE ASSOCIATION STUDY OF ISCHEMIC BRAIN VASCULAR INJURY
Hypertension and the associated renal and cardiovascular complications are a serious health problem in the Unites States. Approximately 65% of hypertensive patients do not have their blood pressure controlled and women are more likely than men
ROLE OF THE RENIN-ANGIOTENSIN SYSTEM IN SEXUAL DIMORPHISMS IN THE DEVELOPMENT OF
The overall goal of this project is to increase understanding of the transcriptional regulation of vascular endothelial gene expression, especially during development of the embryonic vascular system. Ets family transcription factors have been
Regulation of Vascular Endothelial Gene Expression
Cyclic AMP is a highly versatile second messenger in the heart, transducing an array of different receptor stimuli into coordinated regulation of cardiac functions including excitation-contraction (EC) coupling and gene transcription. But how c
Quantitative analysis of cAMP compartmentation in heart
Carcinoembryonic antigen related cell adhesion molecule 1 (CEACAM-1) is atransmembrane protein found on leukocytes, endothelium, and epithelium. Its activation canattenuate colitis in murine models. Microarray analysis revealed that CEACAM-1 is
CEACAM-1A REGULATES GRAFT-VERSUS-HOST-DISEASE AFTER ALLOGENEIC HSCT
DESCRIPTION (provided by applicant): The Role of Zinc Finger Genes in Leukemogenesis: The objective of the proposed study is to understand normal hematopoiesis and the malignant transformation of hematopoietic cells by identifying the biologica
ARRA The Role of Zinc Finger Genes in Leukemogenesis
Obesity is one of the most pressing public health problems in the United States. Through its negative influence on cardiovascular disease, diabetes, and cancer, obesity is a significant contributor to premature morbidity and mortality, as well
Influence of Calorie Labeling on Food Choice
Poor diet and obesity have been linked to increased risks for a number of chronic diseases including cancer and cardiovascular diseases. The proposed research will investigate the relationship between food (candy, baked goods, and chips), bever
Economic Contextual influences on Population Diet and Obesity
Airway hypersensitivity, characterized by exaggerated sensory and reflexogenic responses to inhaled irritants, is a prominent pathophysiological feature of various airway inflammatory diseases (e.g., asthma, bronchitis, etc). Increasing and com
Role of TRPV1 in Airway Hypersensitivity Induced by Inflammation
Global multiple sequence alignment is the most basic step in the comparative study of molecular sequences. It is also the foundation of numerous subsequent biological analyses, such as phylogenetic reconstruction, gene annotation, and three-dim
Error Correction in Multiple Sequence Alignments
Our hypothesis is that we can drastically accelerate scientific discovery by collecting and making visible, comparable, and computable hypotheses, hunches, and theory-specific evidence beyond the dominant paradigm(s) of the field. Accordingly,
LARGE-SCALE DISCOVERY OF SCIENTIFIC HYPOTHESES; COMPUTATION OVER EXPERT OPINIONS
Ultimately, we want to know what factors are important to provide superior prevention, diagnosis, and treatment of human disease.  Unfortunately, interpretation of statistical models in a meaningful way for biomedical research has been lacking
Analysis Tool for Heritable and Environmental Network Associations
Maternal depressive symptoms are associated with reduced maternal quality of life, decreased ability to function, increased infant hospitalizations, reduced breastfeeding, less involvement of mothers with important developmental behaviors such
PREPARATION AND PATIENT EDUCATION TO REDUCE POSTPARTUM DEPRESSIVE SYMPTOMS
While many effective depression treatments (medications and psychotherapies) are available, individuals vary widely in response to specific treatments. Unfortunately, our ability to match any individual to the most effective treatment is hardly
Can Longitudinal Population- Based Data Help to Personalize Depression Treatment?
This proposal aims to test if the size of the MT- and/or MRCA-MRI parameter changes at an early stage of stroke can be used to establish a threshold of BBB damage that portends subsequent HT and if changes of this magnitude or larger can be use
MRI of Acute Vascular Injury and Hemorrhagic Transformation in Ischemic Stroke
The dual outbreaks of HIV infection and early (primary and secondary) syphilis among 15-30 year old African-American men who have sex with men (MSM) in North Carolina (NC) may be driven by men who are co-infected. Biologically, HIV and syphilis
The nexus of drugs, sex networks, HIV and syphilis in young African American MSM
Project Plan: This project will explore novel strategies to accelerate the progress of searching for novel analgesic and anti-inflammatory agents. It is known that research on analgesic and anti-inflammatory agents has been among the most activ
Searching for Novel Analgesic and Anti-inflammatory Agents
Chronic exposure to opioids can lead to dependence, a phenomenon that is manifest by withdrawal-induced somatic, autonomic, and aversive symptoms that critically involve the central nucleus of the amygdala (CeA).  Avoiding physical withdrawal s
Amygdala AMPA GluR2 Deletion and Opioid Dependence
This application is in response to RFA DA-09-016, 'Behavioral Pharmacology and Genetics, Translating and Targeting Individual Differences.' The proposed project will examine the genetic basis of individual differences in inhibitory control (IC)
Genetic basis of smoking abstinence, smoking reinforcement, and inhibitory contro
Ecstasy (primarily containing MDMA) use continues to be major public health problem, especially among young adults. Animal studies suggest that ecstasy is a selective serotonin neurotoxin. However, the effects of ecstasy use on the human brain
Effects of SLC6A4, BDNF and Ecstasy Use on Brain Structure in Young Adults
Infant incubators are widely used in neonatal intensive care units (NICU) for the care of pre-term babies, as they cannot cope with the environment without external help. However, excessive high levels of noise inside an infant incubator have b
An Innovative Hearing Loss Prevention Approach in Infant Incubator
Intrauterine growth restriction (IUGR) alters lung development, increasing the risk of respiratory compromise throughout postnatal life. Vertical integration of the cell-molecular mechanism(s) underlying this respiratory compromise offers a pow
A MOLECULAR APPROACH TO PREVENT PULMONARY DYSFUNCTION IN THE INTRAUTERINE GROWTH
The purpose of this project is to investigate the relative contribution of familiarity and recollection to the development of visual recognition memory in infants.  Recollection involves the retrieval of information about the context in which a
Development of Recollection and Familiarity
The pituitary gland is an endocrine organ that secretes hormones to control various vital processes throughout the body, including growth during childhood, the stress response, sexuality, reproduction, metabolic homeostasis, and lactation. It d
FUNCTIONS OF STEM CELLS IN PITUITARY PLASTICITY
The overall goal of this application is to explore the involvement of non-classical MHC class Ib (class Ib) molecules in thymocyte differentiation during early development by a comparative approach in the Xenopus. Increasing evidence suggests t
INVOLVEMENT OF NONCLASSICAL MHC IN EARLY T CELL ONTOGENY IN XENOPUS
The goal of this R03 proposal is to identify molecular mechanisms underlying the regulation of inhibitory synaptic transmission by the cell adhesion molecule (CAM) neuroligin 2 (NL2). Although it has been established that neuroligins mediate sy
NEUROLIGIN REGULATION OF CENTRAL GABAergic SYNAPSES
RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK (INC)
ARRA - TRANS-NIH RECOVERY ACT RESEARCH SUPPORT.  Behavioral Feedback and Neuronal Lifespan.   To identify behavioral factors that impact neuron cell death in populations of neurons that are normally replaced throughout adulthood.
Behavioral Feedback and Neuronal Lifespan
), family members and caregivers, and HD professionals will be included to identify the important issues/themes related to quality of life in HD. Transcripts from the focus groups will be reviewed by two independent investigators in order to id
Health-Related Quality of Life in Huntington's Disease Research and Practice:  Development of the HDQOL
Award Title – Molecular mechanisms of oxidative stress resistance in an animal model of aging.  The effects of reactive species (ROS) and oxidative stress on protein organization, cellular homeostasis, and apoptosis are recognized as key fact
Molecular mechanisms of oxidative stress resistance in an animal model of aging without senescence
This project will use preclinical mouse models to test two novel applications of the farnesyl transferase inhibitor class of anti-cancer drugs. The ability of farnesyl transferase inhibitors to improve on existing therapies in Burkitt lymphoma
Farnesyl Transferase Inhibitors: Cancer and Immunity
In addition to their roles in transcription, growth and proliferation, and retroviral integration, emerging evidence implicates the High Mobility Group A1 (HMGA1) proteins as important mediators in oncogenic transformation. Enforced expression
Structure Function Studies of the HMGA1 Functional Domains Involved in Malignant Transofrmations
DESCRIPTION (provided by applicant): Many oncogenic viruses interact with cellular oncoproteins to induce cancers in humans. It is of paramount importance to understand the mechanisms by which transforming viruses cooperate with host factors to
MODULATION OF C-MYC FUNCTIONS IN AN HTLV-1 MODEL FOR CARCINOGENESIS
Sjogren's syndrome (SS) is a complex autoimmune disorder causing dysfunction of the salivary and lacrimal glands, leading to dry mouth and dry eyes. SS is also associated with rheumatic disorders such as rheumatoid arthritis. The cause of SS is
EGCG INTERVENTION IN A SJOGREN?S SYNDROME MODEL PRIOR TO DISEASE ONSET
The biomolecule delivery system established from this project can be a useful research tool for basic biological studies which lead to understanding of the nature of human diseases. This system can be further developed to carry functional diagn
Using Quantum Dots and Protein Transduction Domains to analyze cargo dissociation, uptake, and localization in live cells
Creosote is an especially toxic distillate of coal tar containing primarily polycyclic aromatic hydrocarbons (PAHs). Creosote has been used almost exclusively as a means to preserve wood, therefore large scale production has taken place with se
Mechanisms of Immunological Adaptation to a Harsh Chemical Environment
Histone acetylation affects chromatin structure an regulates diverse cellular functions, such as gene expression, DNA repair, and cell proliferation. Many histone deacetylase inhibitors reactivate the transcription of multiple genes that are si
Role of Phospholipase C in Transcriptional Regulation
Continual addition of posterior tail segments beyond the embryonic period is a little known and little understood phenomenon. The immediate goal of this research is to investigate tail elongation and regeneration across life stages (embryo, lar
Continual Addition of Posterior Tail Segments, Regeneration & Hox Gene Expression in a Non-model Salamander
The purpose of this research is to identify the genetic basis underlying directional growth of cells in the embryonic limb (i.e., the limb mesenchyme).  We have previously demonstrated that a structure found at the distal tip of the limb known
The role of Fgf and Wnt5a signaling in directed outgrowth of the limb mesenchyme
Cell survival, division, and differentiation are dependent on a delicate balance between the rates of protein synthesis and degradation. The Ubiquitin-Proteasome System (UPS) is one of the primary pathways for regulating protein turnover in the
F/DHHS/NIH/ARRA/Investigations into the Structure, Function, & Activity of E2-25K
TDP-43 is a major pathological protein in amyotrophic lateral sclerosis (ALS) and some forms of frontotemporal dementia (FTD) and is also present in ubiquitinated inclusions seen in other neurodegenerative diseases. How TDP-43 contributes to ag
MOLECULAR AND GENETIC DISSECTION OF TDP-43 FUNCTION IN NEURODEGENERATION
The National Institute of Alcohol Abuse and Alcoholism has identified hazardous drinking in college students as a significant concern and a research priority due to its significant prevalence on many college campuses and its association with ma
MOTIVATIONAL INTERVENTIONS FOR EXERCISE IN HAZARDOUS DRINKING COLLEGE STUDENTS
The research proposed here will use archival data and multi-level/hierarchal spatial modeling to examine the geography of alcohol outlets and violence, over time, in the city of Boston. We will determine whether and how place matters in regard
THE GEOGRAPHY OF VIOLENCE AND ALCOHOL IN BOSTON
Scientific Rationale: The transition from adolescence to adulthood involves important developmental challenges. Events during this key developmental phase can profoundly shape and influence academic and occupational achievement as well as affec
CENTER FOR HEALTH AND BEHAVIOR 430 HUNTINGTON HALL
We have recently developed potassium channel-mutant mice that are very sensitive to low concentrations of alcohol. Hence, these mice will serve as well-defined rodent models to study the electrophysiological changes, i.e., altered neuronal firi
Role of Kv3-type Potassium Channels in Alcohol Sensitivity - ARRA Stimulus Funding
Premature cell senescence induced by oncogenes and oxidative stress in vitro recapitulates many facets of replicative senescence and in vivo cellular aging. With the recent findings of a tumor suppressor role for senescent cells in vivo, the es
Role of Matrix Metalloproteinase-1 in Endothelial Cell Senescence
Title: Ancillary Studies to the AD Neuroimaging Initiative (R21). This award is for ancillary studies to the Alzheimer ?s Disease Neuroimaging Initiative (ADNI), a multi-site, longitudinal, prospective, naturalistic study of normal cognitive ag
LONGITUDINAL AND CROSS-SECTIONAL WHITE MATTER ANALYSIS OF ALZHEIMER'S DISEASE
Our goal is to generate a mouse model that closely resembles Alzheimer's Disease. In our first attempt we have developed two mouse models of AD that progress from A¿ production and amyloid deposition to hyperphosphorylated native mouse tau at
Progress toward the development of genetically modified mosquito (GMM) strains to be used in a genetic control program for mosquito vectors of malaria has reached a point where most of the scientific community involved in this research are begi
Ecology and Genetics of An. gambiae on Islands
All living cells establish transmembrane electrochemical gradients with the help of primary ion pumps. Primary Na pumps have been discovered in many microorganisms and a transmembrane circulation of Na ions may play a significant role in the ph
Antigen processing is an integral part of cell-mediated immune surveillance and responses that involve MHC- restriction and T cell recognition. Processed antigenic peptides, when presented on cell surface by MHC molecules to T cells, serve as i
Towards Structural Studies of Aminopeptidases in Antigen Processing
Hepatitis E virus (HEV) causes endemic and large epidemics of acute human hepatitis and sporadic cases by a fecal-oral transmission in many parts of the world.  HEV generally infects young adults and the disease has a high mortality rate, up to
Morpholino Antisense Drugs against Hepatitis E Virus
We propose this R21 feasibility study to assess factors related to recruiting rural and minority parents to a study that would involve themselves and their children in an assessment of their behavioral, home environmental and genetic characteri
Recruiting Rural Parents/Infants to Health Research Projects:  Atopic Dermatitis
Bacillus anthracis and other bacterial pathogens are among the more pronounced threats in the arena of bio- terrorism and biological warfare, while the occurrence of resistant strains of other gram positive pathogens (including Staphylococcus a
(ARRA) Novel therapeutic approaches to pathogen inactivation
The purpose of this two year R21 exploratory award is to characterize and confirm the role of inflammatory cells in wound healing and determine whether the subset of innate lymphocytes regulates the wound healing process via modulation of the l
Natural Killer T Cell Modulation of Cutaneous Wound Healing
'Infections associated with indwelling medical devices, particularly catheters account for about half of nosocomial infections in the United States. These infections prolong hospital stay and result in substantial morbidity and mortality. Bacte
Antibiofilm/Antimicrobial Combination for Infections Associated with Vascular Catheters
Candida albicans (CA) is the most commonly isolated fungus associated with biofilms [extracellular matrix (ECM)-encased microbial communities formed on indwelling medical devices which are resistant against commonly used antifungals. The carboh
Role of Extracellular Matrix Proteins in Candida Biofilm Formation
The awarded project aims to comprehensively identify and characterize genes involved in resistance to human endogenous antimicrobial peptides such as cationic defensin and anionic dermcidin, in Gram-negative bacteria E. coli and Salmonella ente
Genetic determinants of antimicrobial peptide resistance in Gram negative bacteria
DESCRIPTION (provided by applicant): After budding from the cell, retroviruses (such as HIV) undergo a complex spontaneous process called maturation that is required for their infectivity. During maturation retroviruses undergo dramatic interna
The bacterium Bacillus anthracis causes anthrax in humans; as a bioterrorism agent the bacteria are a threat to public health. Our laboratory has recently reported a cell wall polysaccharide of a B. anthracis (termed HF-PS) with a structure spe
Biosynthesis & Function of a Bacillus anthracis-specific cell wall polysaccharide
Type I (IFN-?/?) and type III (IFN-?s) IFNs are important components of the host antiviral response.  Although type III IFNs possess intrinsic antiviral activity similar to that of type I IFNs, they signal through specific unique receptor compl
Evasion of antiviral protection by poxvirus-endoded interferon antagonists
These studies are focused on the molecular structures of protein complexes that form between the HIV virulence factor Nef and host cell signaling proteins (Src-family kinases) in HIV-infected cells.  Formation of these complexes is important to
Structural Biology of HIV Nef-Scr Family Kinase Complexes
Overview: Aspergillus fumigatus is an inhaled fungus that can infect human patients with immune suppression. At this time, most individuals that become infected by this organism do not survive, despite aggressive medical management. The long-te
Non-Oxidative Resistance to A. fumigatus by Alveolar Macrophages
Asthma is a disease of chronic inflammation marked by periodic bouts of acute exacerbations of airway obstruction, and early sub-clinical eosinophilic pulmonary inflammation precedes the development of asthma in children.  Why certain individua
ST6Gal-1 Sialytransferase in Allergic Airway Inflammation
Congenital infection with human cytomegalovirus (HCMV) occurs in approximately 40,000 infants a year in the United States annually and is the leading viral cause of birth defects. These problems together with the severe disease that HCMV causes
DEVELOPMENT OF A NOVEL VACCINE AGAINST CONGENITAL CYTOMEGALOVIRUS INFECTION
Tuberculosis, caused by Mycobacterium tuberculosis, continues to be a public health problem in many countries including the United States because of its prevalence in HIV-infected patients and also due to the emergence of multi-drug resistant (
EFFECT ULTRAVIOLET RADIATION ON LATENT M TUBERCULOSIS INFECTION IN GUINEA PIGS
The emergence of bacterial resistance to antibiotics continues to be a significant public health challenge. Factors contributing to the rise in antibiotic resistance include widespread and inappropriate prescription of broad spectrum antibiotic
NOVEL METHODOLOGY FOR RAPID ANTIBIOTIC SUSCEPTIBIILITY TESTING IN S. AUREUS
Protein deubiquitination in lymphocyte signaling:  The long-term goal of this laboratory is to understand the process of ubiquitin conjugation in the regulation of immune responses. Protein ubiquitination is carried out by a cascade of enzymati
Protein deubiquitination in lymphocyte signaling
Despite attractive, ionizing radiations cannot be directly applied in the treatment of bacterial infections since bacteria are extremely insensitive to radiations. The lethal radiation dose for bacteria is at least 1,000 times higher than the w
Intracellular Radiation as a Novel Approach for Infection Treatment
Clearance of many viral infections is critically dependent on the function of CD8 T cells in the immune system.  Recent results have shown that CD8 T cells become functionally defective when CD4 T cell help is absent. This loss of functionality
MOLECULAR BASIS OF DEFECTIVE CD8 T CELLS DURING CHRONIC VIRAL INFECTION
Studies of virus specific immune responses in HIV exposed and infected individuals as well as SIV vaccine studies in macaques suggest that it is unlikely that vaccine approaches that stimulate a single arm of the immune system will provide effe
IMPORTANCE OF ANTIGEN SPECIFIC IMMUNOGLOBULIN RESPONSES IN CONTROLLING SIV/SHIV I
Neisseria gonorrhoeae is the causative agent of gonorrhea, one of the most prevalent infectious diseases in this country. In addition to local infection, manifested as urethritis or cervicitis, the gonococcus can cause serious complications, in
This research proposal details our plan to establish the 'proof of concept' that will support a subsequent R01 application to perfect and extend our methodology to expedite the functional and therapeutic analysis of hypothetical proteins identi
Revealing Functions for Newly Discovered Proteins by FAST-NMR
This is a two year award to analyze the methylcitrate cycle in Candida glabrata, an important human pathogen. This cycle is a fungal specific cycle important in detoxification of propionyl-CoA by C. glabrata. Propionyl-CoA is a byproduct of fat
AIDS OPPORTUNISTIC PATHOGENS: TARGETING THE METHYL CITRATE CYCLE
HIV causes AIDS in humans. Integration of HIV DNA by integrase into chromosomes is necessary for virus replication which cause AIDS. We investigate the mechanisms associated with integration and prevention of integration by clinical inhibitors.
HIV integrase/DNA complexes and concerted intergration
ARRA Creation of a tissue culture model for Toxoplasm,a gondii sexual development
A major risk associated with implanted medical devices is their high rate of infection. Bacteria that colonize medical devices form matrix-encased biofilms that resist antimicrobial therapy and are often difficult or impossible to eradicate. Th
Anti-staphylococcal activities of A. actinomycetemcomitans dispersin B
The overall purpose of the award is to understand hepatitis C virus (HCV) life cycle and the HCV-associated steatosis with implications for the development of novel antiviral therapeutics.  HCV infection can cause many liver diseases including
To analyze how immune responses generated against respiratory viral infection impact immunological and pathological responses to a subsequent pulmonary bacterial infection. Our goal is to identify the molecules and pathways involved in increase
Innate and adaptive immune responses at the respiratory mucosa
The long-term goal of this project is to understand how natural killer T (NKT) cells recognize and respond to microorganisms in the respiratory mucosa. We have previously shown that NKT cells in the lungs play a critical role in the development
NKT cells recognize and respond to microbes at mucosal surfaces
This award will investigate the mechanisms regulating the maintenance of hyporesponsiveness in mucosal T cells and the environmental signals that enable this normally quiescent mucosal T cell to respond when needed. Signal transduction emanatin
The mucosal surfaces of the body are the portal of entry for many pathogenic micro- organisms yet most licensed vaccines are delivered parenterally and are ineffective at inducing mucosal immune responses. In addition, exposure of mucous membra
Mucosal Adjuvants Targeting Dendritic Cells
Peripheral induction of antigen-specific Foxp3+CD4 T cells, or regulatory T cells (Tregs), is a potential pathway to treat autoimmune diseases. It is also represents an undesirable outcome of the immune response, which limits recovery from chro
Translational control of regulatory T cell induction
Legionella pneumophila (Legionella) is the causative agent of a severe pneumonia called Legionnaires' disease. Legionnaires' disease affects mainly the elderly and immune-compromised individuals. Each year, 8,000-18,000 people with legionellosi
(ARRA) How can caspases control intracellular pulmonary pathogens
neutrophils such that a secondary insult, which would otherwise be tempered in an unprimed cell, now results in an exaggerated inflammatory response. The excessive and unregulated release of cytokines and toxic oxygen radicals causes damage to
TOWARDS A MOLECULAR SIGNATURE OF NEUTROPHIL PRIMING
Mucin glycoproteins (mucins) protect the lung against pathogens and environmental toxins. Mucins are overproduced in the airways of patients with chronic lung diseases, which contributes markedly to patient morbidity and mortality. Inflammatory
IL8-induced Post transcriptional Regulation of the MUC5AC mucin gene
Protein kinases are important regulators of cell proliferation, migration, and differentiation. Cancer cells of many types over-express protein kinases. Drugs that inhibit specific protein kinases are now used to treat some human cancers. Anti-
Protein tyrosine Kinases of A. Trypansome
Biosciences Bldg. Cellular Biology Dept. Room 709
d-Limonene, a monocyclic monoterpene, is a major component in the essential oils of citrus fruits. Oral feeding of d-limonene has been shown to prevent carcinogen-induced rat mammary carcinoma during the initiation and promotion stages as well
Clinical Study of Disposition and Biological Activity of d-Limonene
The assessment of volumetric change of enhancing tissue is regarded as an important parameter used by clinicians when seeking to monitor the response of brain neoplasms to therapy. Unfortunately, direct computation of enhancing volume requires
COMPUTER ASSISTED IDENTIFICATION AND VOLUMETRIC ANALYSIS OF ENHANCING COMPONENTS
Quality of life (QOL) changes by the week, the day, and the hour; how these moments affect us becomes our QOL.  In medical research, we use standardized questionnaires that usually try to summarize these changing states and feelings over a long
The Time Distribution Method for Measuring Clinically Valid Quality of Life State
PALO ALTO MEDICAL FOUNDATION FOR HEALTH CARE, RESEARCH AND EDUCATION (INC)
Prostate cancer is the second most frequent cause of cancer mortality for men.  Definitive, comparative treatment outcome data for localized prostate cancer are lacking.  Men must choose among treatment options that may offer similar mortality
Prostate Cancer Nurse-Navigator Treatment Decision Support
Prostate cancer is a leading cause of cancer related morbidity and mortality in US males. Despite initial treatments with curative intent for localized stage (surgery or radiation) approximately one third patients will progress to advanced sta
A proteomics Approach for Identifying Predictive Factors to Androgen Deprivation.
The present award is being utilized to develop an all optical platform to form lipid bilayers from water-in-oil emulsions using an inverted fluorescence microscope Optical radiation will be used to mobilize water droplets coated with a lipid mo
BCR/ABL fusion tyrosine kinase results from t(9;22) reciprocal chromosomal translocation and is leukemogenic only when expressed in a hematopoietic stem cells (HSCs) with self-renewal capacity thereby inducing leukemia stem cell (LSC). LSCs are
GENOME INSTABILITY IN LEUKEMIA STEM CELL
The specific aims are to assess tumor marker specific nanoprobes as potential therapeutics and diagnostics. Specific Aim 1 was to assess tumor marker specific magnetite nanoprobes in their ability to detect markers associated with tumor maligna
Therapeutic Evaluation of Magnetic nanoprobes Specific for Malignant Tumor Marker
Aberrant norepinephrine [NE] neurotransmission in the human brain is linked to mood disorders, depression, drug addiction and neurodegenerative diseases. ? -synuclein [? -Syn], a member of the synuclein family of proteins, is expressed in monoa
GAMMA-SYNUCLEIN-MEDIATED REGULATION OF NOREPINEPHRINE TRANSPORTER
This project concerns the physiological mechanisms of brain oscillations in the neocortex, a structure vital for perception, thought and memory. Brain oscillations are believed to be important for sensory processing, cognitive states such as at
HIGH-FREQUENCY RHYTHMS OF THE NEOCORTEX: MECHANISMS AND INTERACTIONS
Health Relatedness: Over 400,000 Americans are afflicted with multiple sclerosis (MS), with severe disability ultimately affecting ~85% of the total MS population. Disability in MS is primarily due to demyelination and axonal injury. Axonal inj
Functional Link Between Innate Immunity, Oligodendrocyte Development, and Myelina
Huntington's disease (HD) is a chronic neurodegenerative disease resulting from an autosomal dominant mutation in the gene for the huntingtin protein (htt). It is unknown, however, how mutant huntingtin causes a stereotyped pattern of neuronal
Dysregulation of MicroRNAs in Huntington's Disease
Generate Shank3 conditional knock-out mice line. This proposal is responsive to RFA-MH-09-170, the Recovery Act Limited Competition: Research to Address the Heterogeneity in Autism Spectrum Disorders (R01). As noted in the RFA, Autism spectrum
Elucidating the Roles of SHANK3 and FXR in the Autism Interactome
Methamphetamine (METH) is an addictive psychostimulant with extremely high relapse rates. Effective pharmacotherapies to treat METH addiction, and in particular to counter relapse have not yet been developed. Research in animal models implicate
CRF System and Methamphetamine Extinction
DESCRIPTION (provided by applicant): Recent years have seen prominent calls for quality improvement within the health-care sector. Nevertheless, the social value of quality turns on its benefits and costs. The purpose of this two-year research
QUALITY AND COSTS IN HOSPITALS: WHAT CAN WE LEARN FROM MEDICARE PATIENTS?
Our primary aim is to assess the association of mtDNA polymorphisms and heteroplasmy with active energy expenditure and resting metabolic rate in the elderly. We will carry out our primary aim in a test of healthy samples from the Health, Aging
Mitochondrial DNA Variation in Human Energy Expenditure and Metabolic Rate
A decrement in spatial learning ability in normal aging has consistently been correlated with blunted receptor signaling mediated through the muscarinic and metabotropic glutamate receptor-G1q/11 signaling transduction system. The role of G1q/1
Knockdown of Galphaq to model age-related cognitive impairment
DESCRIPTION (provided by applicant): Leishmania parasites cause a spectrum of devastating diseases known as leishmaniasis. A critical step in Leishmania infection is the differentiation from replicative, non-virulent procyclics to non-replicati
Roles of Sphingolipid Metabolites in Leishmania Differentiation
Kingella kingae is a fastidious gram-negative coccobacillus of the Neisseriaceae family and is a normal inhabitant of the human oropharyngeal flora. This bacterium belongs to HACEK group and can cause infective endocarditis. Recently, as the re
Characterizaton of a Kingella Kingae leukotoxin
Upon bacterial infection, host cells release chemicals that damage the bacterial DNA. Such damage, if left unrepaired, leads to bacterial death. Recombination-based DNA repair proteins, specifically the RecBCD and AddAB helicase-nucleases, are
Novel Antibacterial Drugs Targeting DNA Repair Enzymes
DESCRIPTION (provided by applicant): Project Summary Muscle wasting syndrome and cachexia are associated with many degenerative diseases, like cancer, AIDS, and other systemic diseases. Muscular atrophy is primarily a result of increased protei
A COMPARATIVE APPROACH TO EVALUATE MUSCLE GROWTH IN AN INDETERMINATE GROWTH MODEL
Elucidation of the molecular mechanisms whereby PARP-1 regulates IL-10 gene expression will enable us identify key steps in the regulatory pathway that may be explored as potential targets of therapeutic intervention in juvenile arthritis. More
PARP-1 in Juvenile Idiopathic Arthritis-associated IL-10 Promoter Polymorphisms
During embryonic development, a single-layered ectodermal cell layer transforms into a multi- layered epidermis. The multi-layered or stratified architecture of the epidermis is essential for its barrier function - allowing it to prevent both d
MECHANISMS DRIVING ASYMMETRIC CELL DIVISION IN THE EPIDERMIS
Gene therapy has emerged as a promising strategy for bone repair and regeneration. The key to its success is to deliver the genes of interest to the target bone fracture site that can be expressed at suitable levels. Both ex vivo and in vivo ge
BONE-SEEKING AND CELL-TARGETING NON-VIRAL VECTORS FOR BMP-2 GENE DELIVERY
This project is focused on elucidating molecular mechanisns of skeletal abnormalities in tricho-rhino-phalangeal syndrome.Mutations of the human TRPS1 gene cause a dominantly inherited skeletal dysplasia tricho-rhino-phalangeal syndrome (TRPS).
The role of Trps1 transcription factor in endochondral bone formation
Primary liver cancers are highly malignant tumors in human and their incidences are rising in the United States.  The overall survival of patients with liver cancer is grim and currently no efficient chemoprevention is available. The current pr
Inhibition of EP1 in Conjunction with Sorafenib for Liver Cancer Chemoprevention
Tobacco smoke is the single most preventable risk of cancer and is responsible for lung cancer being the highest in incidence worldwide. Research on the association between tobacco and cancer relied on questionnaire data for tobacco exposure as
HAIR AND TOENAIL NICOTINE AS BIOMARKERS OF ACTUAL POPULATION EXPOSURE TO TOBACCO
DEVELOPMENT AND EVALUATION OF SPATIAL SURVIVAL MODELS General Aims The general aim of this project is to develop new and flexible statistical methods to estimate survival probabilities within spatial cancer survival data. We are interested in d
DEVELOPMENT AND EVALUATION OF SPATIAL SURVIVAL MODELS
Non-Hodgkin lymphoma (NHL) is the fifth most common cause of cancer death in the United States with a five-year survival rate of 64% overall (1996-03). Despite the promise of prognostic immune signatures, measurement of gene expression using mi
Impact of Lifestyle with Tumor Pathways and Microenvironment on Lymphoma
Adjuvant chemotherapy and tamoxifen have been shown to reduce the risk of contralateral breast cancer (CBC) among women with a previous history of breast cancer. It is well recognized that not all individuals metabolize drugs with the same effi
Pharmacogenetics of Tamoxifen and Chemotherapies and Risk of Contralateral Breast Cancer
Telomere length measured in peripheral blood leucocytes (PBLs) has emerged as a principal biomarker of aging and cancer risk. Telomeres are TTAGGG repeat complexes at the end of chromosomes that protect against degradation, fusion, and aberrant
Association of Telomere Length with Colorectal Cancer and Adenoma
The transition from adolescence to young adulthood is marked by declines in healthful behaviors such as diet, physical activity, and increases in obesity, thereby establishing early patterns of unhealthful behaviors in mid-adulthood that can le
Feasibility of a Healthy Eating and Physical Activity program Among a Diverse Sample
During the past 20 years, obesity has risen at an epidemic rate in the United States. It is anticipated that with increased obesity colon cancer cases will increase; therefore, research regarding how obesity increases the risk of colon cancer i
Biomarkers of obesity inflammation and colon cancer risk
While some individuals are able to casually use a drug without it interfering with their day-to-day activities, others become addicted, unable to shift their thoughts and actions away from drugs and drug-associated stimuli. The factors underlyi
Individual Differences in Incentive Salience Attribution: Relevance to Addiction
Molecular & Behavioral Neuroscience Institute
This project seeks to understand the neural basis involved in implicit associative processes through the imaging (fMRI) of drug-relevant memory associations. Complex associative learning and memory processes influenced by reinforcing drug use r
Functional Imaging of Implicit marijuana Associations during IAT Performance
Characterizing the 3-year course of cannabis involvement in NESARC Cannabis is the most commonly used illegal psychoactive substance in the United States and in developed nations. For instance, in the U.S., over 40 percent of 12th graders repor
CHARACTERIZING THE 3-YEAR COURSE OF CANNABIS INVOLVEMENT IN NESARC
This proposal concerns the study of Men's Assessment of Social Support and Risk Networks. Unfortunately, relatively little is known about the particular social consequences of the aging of the HIV/AIDS population, either for the challenges face
MEN'S ASSESSMENT OF SOCIAL SUPPORT AND RISK NETWORKS
Research into the role of neurotransmitter systems in the reinforcing effects of cocaine has traditionally focused on monoamines; however recent studies in rodents indicate a strong involvement of glutamatergic mechanisms, particularly during a
Effect of Cocaine Self-Administration on Metabotropic Glutamate Systems
Human genetic studies have linked polymorphisms in the gene encoding the GABAA receptor ?2 subunit, GABRA2, to substance abuse, but neuronal mechanism and brain regions involved are still unknown. Recent experimental evidence suggests that a gl
Psychostimulant actions: essential role of a2-GABA-A receptors in the NAc
DESCRIPTION (provided by applicant): Despite decades of committed research, no agents are clinically available to combat psychostimulant abuse and addiction. This prodigious void can be linked to sparse information on the 3-D structure and func
NON-TROPANE IRREVERSIBLE DOPAMINE TRANSPORTER LIGANDS
Anandamide (AEA) is a naturally occurring ligand that binds to cannabinoid receptors and is widely distributed in the body, particularly the nervous system. Although AEA was described in 1992, the pathway for its synthesis has not been definiti
IMAGING VARENICLINE EFFECTS ON NICOTINE & DOPAMINE: GENE MODULATION Nicotine dependence (ND) is a complex behavior governed by genetic and environmental determinants. In fact specific variations in the genes that influence nicotinic receptors h
IMAGING VARENICLINE EFFECTS ON NICOTINE & DOPAMINE:  GENE MODULATION
Tobacco smoking is addictive and data from epidemiological studies have suggested that genetic factors play an important role in smoking and nicotine addiction. Multiple recent studies indicate that variants in the CHRNA5/CHRNA3/ CHRNB4 locus o
Variants in Nicotine Receptors and Pharmacogenetics
Bone degenerative diseases such as osteoporosis, periodontitis, and rheumatoid arthritis are major health care concerns for the elderly population that is rapidly increasing in the US. An osteoporotic fracture can cause significant morbidity an
Our long-term goal is to elucidate the causes and pathophysiology of osteonecrosis of the jaw (ONJ) in order to create the basis for new effective strategies for prevention and treatment.  The objectives of this proposal are to develop an anima
Pathophysiology of Biphosphonate-Induced ONJ in a Novel Animal Model
Activating mutations in FGFR2 cause craniosynostosis syndromes such as Apert and Crouzon syndromes. Recent genetic evidence has also indicated that the ERK MAPK pathway and immediate early genes play critical roles in the regulation of bone for
SRF in MAPK-Dependent Cranial Suture Development
DNA microarrays are in principle particularly well suited for real-time identification of known or related species.  Microarrays are inherently parallel, as hundreds to thousands of nucleic acid signatures can be probed for in a single hybridiz
DEVELOPMENT OF A COMPUTATIONAL MODEL FOR IMPROVED DIAGNOSTIC ACCURACY OF DNA MICR
DESCRIPTION (provided by applicant): The goal of the proposed research is to examine how workers in the United States encounter multiple negative experiences at work, and how the accumulation of these experiences over the career is associated w
Negative Working Conditions and Health Across the Career
Over 17% of U.S. adolescents are considered overweight. The proposed study will advance our understanding of the dynamic relationship of overweight status and psychosocial adjustment problems during the period of pubertal transition, which will
Obesity and Psychosocial Adjustment During Adolescence
The interactive acute health effects of environmental tobacco smoke (ETS) and ambient fine particulate matter (PM2.5) exposure on health of children with asthma will be analyzed. The results will allow for a better understanding about how child
Ambient PM2.5 and ETS exposure: interactive health effects for asthmatic children
DESCRIPTION (provided by applicant): Despite the fact that contraceptives have the potential to nearly eliminate pregnancy and sexually transmitted diseases (STDs), data from the 2002 National Survey of Family Growth show that almost half the p
SUBJECTIVE EXPECTATIONS AND BIRTH CONTROL CHOICE
The investigators' work to date has identified two dynamic mesodermal domains in the developing vertebrate embryo. The primaxial domain is populated exclusively by cells from the somites. The abaxial domain is made up of myoblasts from the somi
Amphibian Models for Bodywall Patterning
To provide support for initiatives funded under The American Recovery and Reinvestment Act of 2009 (ARRA). These projects will provide economic stimulus to the nation while furthering the NIH mission to uncover new knowledge that will lead to b
Relationship Experiences among Puerto Rican Heterosexual HIV Serodiscordant Couples
Pressure ulcers significantly affect quality of life and overall healthcare costs of wheelchair users with spinal cord injury (SCI). Current clinical practice includes using wheelchair power seat function (PSF) to attain specific seating angles
Effect of Power Seat Function Usage on Tissue Viability in Wheelchair Users with SCI
Idiopathic Pulmonary Fibrosis (IPF) is a deadly disease without a clearly-defined etiology. Because the incidence increases with age, it is plausible that environmental effects may be important. Recent data indicate re-expression of development
EPIGENETIC ALTERATIONS IN IPF FIBROBLASTIC FOCI
Microarray analysis is widely expected to further our understanding of disease phenotypes and yield robust gene expression signature based predictors of clinical outcome. However, as it has been frequently demonstrated in the literature, insuff
Increasing the realiability of clinical microarray data analysis by systematic bia
Ataxia Telangiectasia (AT) is a genetic disorder that surprisingly manifests itself only in certain tissues. This tissue preference is especially relevant to the AT-affected CNS, in which degeneration of the cerebellar cortex and subsequently m
ATAXIA TELANGIECTASIA IN THE CNS - CAUSE AND EFFECT
The cerebellum is critical for motor coordination and cognitive function. Granule neurons are a key component of cerebellar circuitry and are thought to represent the cell of origin for the pediatric brain tumor medulloblastoma. While the devel
Identification of a Mitogen for Neuronal Progenitors in the Embryonic Cerebellum
Agency for Healthcare Research and Quality
This R13 Large Conference Grant from the Agency for Healthcare Research and Quality (AHRQ) supports the United States Cochrane Center (USCC) in collaboration with the consumer advocacy coalition, Consumers United for Evidence-based Healthcare (
Consumers United for Evidenced-Based Hea
F1Fo-ATP synthase is the smallest known biological motor, found from bacteria to man. It is the fundamental means of cell energy production in animals, plants, and almost all microorganisms in the form of adenosine triphosphate (ATP) from adeno
Molecular Modulation of Catalytic Sites of Escherichia coli F1F0 ATP Synthase
This Academic Research Enhancement Award (AREA) grant was provided from the National Institutes of Health (National Institute of Arthritis and Musculoskeletal and Skin Diseases) to fund a grant application titled 'Manzamine A as an anti-inflamm
Manzamine A as an Anti-inflammatory Treatment for Rheumatoid Arthritis
This proposal will investigate the role of exercise (mechanical loading) during growth on lifelong skeletal health. Exercise is a commonly advocated intervention for osteoporosis as the skeleton is mechanosensitive and can adapt to loading. How
Long-term skeletal effects of exercise during growth
ATP produced within the mitochondrial matrix through a process termed oxidative phosphorylation (OXPHOS) is transported out of the mitochondria to the rest of the cell via a metabolite carrier proteins termed the ADP/ATP carrier (AAC) family lo
MOLECULAR ANALYSIS OF THE MITOCHONDRIAL ADP/ATP CARRIER PROTEIN COMPLEXES
MONTCLAIR STATE UNIVERSITY STUDENT GOVERNMENT ASSOCIATION SCHOLAR, THE
The goal of this research is to understand the processes of forming a temproal interpretation of sentences, and how these processes are related to the processing of basic content. The knowledge that is gained will provide a foundation for impro
Eye-Tracking Analysis of Temporal Processing in Sentence Comprehension
This grant is funding primary research in developmental neurobiology that involves undergraduate students in the research process.
Understanding Trio and Abl in Drosophila Axon Guidance Through Genetic Modifiers.
CHARLES DREW UNIVERSITY OF MEDICINE AND SCIENCE
Investigation of the effects of increased neurosteroid exposure on the maturing cerebral cortex highlights the importance of the downstream effects of stress on cortical development. In particular, nonspecific stress is the most consistent fact
DEVELOPMENTAL EFFECTS OF NEUROSTEROID EXPOSURE AND THE ETIOLOGY OF SCHIZOPHRENIA
Charles Drew University of Medicine and Science
Endocrine, Metabolic & Nutritional Diseases
Endocytosis and cell signaling are important for viability of eukaryotes. In Trypanosoma brucei, little is known about cell signaling because the major receptors studied in model eukaryotes are unrecognizable in the parasite genome. T. brucei h
Signaling GPI-phosphilipase C of a Trypanosome
Consistent, albeit moderate alcohol consumption in human adults results in permanent alterations in the cerebellum that discretely disrupt motor functions and become more pronounced with age. This is a major health concern as the aging populati
ARRA: Imbalances in Calcium Homeostasis: Mechanism Behind Ethanol-Related Dendritic Degeneration
of the central nerhvous system during pregnancy stages.  This will provide information in finding therapeutic ways for the treatment of fetal alcohol exposure.
Molecular mechanism of ADNF and ADNP peptides in prevention of mitochondrial dysfunction against prenatal alcohol exposure
Chronic alcohol abuse has a variety of pathological consequences including damage to liver, brain and other organs. Some of these pathological effects can be attributed to ethanol metabolism. Ethanol is metabolized to acetaldehyde by the alcoho
Role of Mitochondrial Aldehyde Dehydrogenases in Ethanol Metabolism and Toxicity
This proposal explores consequences of chronic alcohol (ethanol; EtOH) exposure and withdrawal on sex- specific astrocyte activation, expression and function. Chronic EtOH abuse is associated with neurotoxicity and reactive astrogliosis, but th
Sex dependent astrocyte activation and alcohol-induced neurotoxicity
ARRA Use of Social Networking Web sites For Problem Drinking Screening in Adolescents
Werner syndrome (WS) is an 'adult-onset' genetic disorder characterized by multiple features consistent with accelerated aging (i.e., a 'segmental progeroid syndrome'). An aged appearance and common age-related disorders such as type 2 diabetes
NONSENSE-MEDIATED DECAY ARRAY ANALYSIS OF ATYPICAL WERNER SYNDROME
Fibromyalgia (FM) is a clinical state of widespread musculoskeletal pain with multiple tender points that is most common in postmenopausal women. Fatigue, particularly post-exertional, is an additional hallmark of the syndrome. FM likely has no
Contribution of altered muscle hemodynamics to fatigability in older persons with
An underlying viral infection can modulate secondary pathogen encounters in different ways. For instance, virus infections such as HIV or Measles are associated with immunosuppression and enhanced susceptibility to opportunistic infections, res
VIRUS INTERFERENCE WITH TOLL LIKE RECEPTOR RESPONSE ON DENDRITIC CELLS
The type III secretion system (TTSS) is essential for the pathogenesis of a number of gram-negative human pathogens, including three Yersinia species; Y. pseudotuberculosis and Y. enterocolitica, that cause infection of intestinal lymphoid tiss
ARRA:  Regulation of Pore Formation by Type III Secretion System
The Gram positive bacterium Arcanobacterium haemolyticum, is an under-recognized cause of pharyngitis and disseminated disease, including meningitis, osteomyelitis and endocarditis. To date, no molecular characterization of A. haemolyticum viru
Role of PLD in the pathogenesis of Arcanobacterium haemolyticum infections
Epidemic typhus, also known as Gaol fever, Jail fever, or Famine fever, is caused by the Gram-negative bacterium Rickettsia prowazekii. This louse-borne disease has been responsible for devastating widespread epidemics throughout history, espec
The objective of this study is to identify mosquito genes critical for arbovirus replication. In particular, antiviral genes that antagonize viral replication in mosquitoes are of interest since these genes can be targeted for control of virus
Genomics of Antiviral Responses of Anopheles Gambiae Against O'nyong-nyong Virus
Role of ICOS-B7h Regulatory Costimulatory Pathway in Fetomaternal Tolerance The fetus has paternal antigens which can evoke strong allogeneic T cell responses. However, in general the semi-allogeneic fetus is not usually rejected indicating the
Role of ICOS-B7h Regulatory Costimulatory Pathway in Fetomaternal Tolerance
Activation of NKT cells by cytomegalovirus: The innate immune response to pathogens is critical for the control of infection prior to the development of adaptive immunity. NKT cells with an invariant T cell antigen receptor (TCR) ? chain (iNKT
Activation of NKT cells by cytomegalovirus
To evaluate the potential for developing an antiviral chemotherapeutic strategy based on the intrinsic defense mechanism of human cells: mutagenesis of single-stranded DNA by cytidine deaminase APOBEC3G (A3G). Human immunodeficiency virus 1 (HI
Rescuing the anti-HIV activity of APOBEC3G with small-molecule chaperons
Vaccination for protection against sexually transmitted diseases such as acquired immunodeficiency syndrome (AIDS) caused by human immunodeficiency virus (HIV) infection should concentrate on inducing strong antigen-specific humoral and cellula
ALPHA-GALACTOSYCLERAMIDE AS A MUCOSAL ADJUVANT FOR HIV ANTIGENS
Helicobacter pylori is a bacterium that commonly infects the stomach, where it causes inflammation (gastritis) in all individuals and peptic ulcer disease or gastric cancer in some. The most intensively studied bacterial factor associated with
Helicobactor pylori and the gastric microbial community in rhesus macaques
Group A Streptococcus (GAS) employs multiple defense strategies to resist killing by reactive oxygen species (ROS) formed either by reduction of atmospheric oxygen or by phagocytes upon activation of the host inflammatory response. These defens
Group A Streptococcus responses to oxidative stress
The purpose of the proposed study is to explore the benefits of 'Exercising Together' - a partnered strength training program for married couples coping with prostate cancer - on the physical and emotional health of prostate cancer survivors (P
EXERCISING TOGETHER: AN INTERVENTION FOR PROSTATE CANCER SURVIVORS AND SPOUSES
Malignant gliomas are the most common and lethal adult primary brain tumors. Despite aggressive therapeutic interventions, these tumors are difficult to eradicate due to their diffusely infiltrative growth pattern and frequent resistance to che
MRI-PET GUIDED STEREOTACTIC BIOPSY OF HIGH GRADE GLIOMAS
An individual's relevant health information is stored in multiple, independent sources (Institute of Medicine 2001). Therefore not all the clinical information useful to providers is available during a patient encounter, meaning decisions frequ
FACTORS MOTIVATING & AFFECTING INFORMATION-SEEKING IN A HEALTH INFORMATION EXCHANGE
Epidemiological data demonstrates strong gender bias in hepatocellular carcinomas. This phenomenon cannot not be attributed to gender differences in life style factors. Moreover, there is no evidence implicating direct effect of sex hormones in
Developmental Aspects of Sexual Dimorphism of Hepatic Tumors: Zebrafish Model
mice on a high-fat Western stye diet, and is the extract more effective than inorganic Ca2+ alone? Second, is the extracellular calcium-sensing receptor (CaSR) the critical target for the chemopreventive effects of the algae extract? To addres
DIETARY MARINE ALGAE EXTRACT AND COLON CANCER CHEMOPREVENTION
Cancers of the large intestine cause more deaths in the United States than those arising in any other organ but the lung. Despite tremendous progress, the factors that initiate and promote the progression of neoplasia in the colon are incomplet
Escherichia coli and Colorectal Carcinogenesis
Treatment regimens and clinical intervention are driven by information obtained by ongoing patient monitoring. Current methods for protein biomarker detection are based on well established techniques, including gel electrophoresis and antibody-
Quantitative Mass Spectrometry Assays to Detect Multiple Myeloma and Assess Relap
Men and women respond differently to cocaine. Although epidemiological data show that more men than women abuse cocaine, there is preclinical and clinical evidence indicating that females are more vulnerable to its psychostimulant effects. Evid
A Role for the Medial Preoptic Area in Regulating Gender-Sensitive Differences in Response to Cocaine
Drug abuse is a major public health concern and preventing the onset of problematic drug use has become a public health priority. Individuals classified as high sensation seekers are vulnerable to drug abuse and other risky behaviors that may r
Exploring the neurobiological response to anti-drug media messages with fMRI
Although there is mounting evidence that strategically designed and targeted public service announcement (PSA) campaigns can reduce drug abuse by adolescents, a recent report by the Government Accountability Office concluded that the $1.4 billi
BRAIN IMAGING THE EFFECTS OF HIGH SENSATION VALUE ANTI-DRUG PSAs
This revised R21 research grant application represents a partnership between the YMCA of Greater New York (YNY) and Columbia University. Over 2 years, the planned study will adapt a parent-involvement program for combined use with a previously
Drug Abuse, Adolescent Girls, and Prevention: YMCA Community
BIOMEDICAL RESEARCH INSTITUTE OF NEW MEXICO
VA Progress Report, Fourth Quarter 2011 ? Dr. Cynthia Geppert, MD, PhD, MPH ?A Survey Study of Informed Consent Processes in Addiction Treatment?  The fourth quarter of the study?s third year has continued to focus on analyzing data and submitt
A SURVEY OF INFORMED CONSENT PROCESSES IN ADDICTION TREATMENT
The aim of the study is to examine racial differences in sexual partner characteristics and determine whether neighborhood drug markets influence sex partner characteristics and sexually transmitted infections (STI) status of non-illicit drug u
RACE AND HIV-RISK: CONTEXTUAL AND NEUROCOGNITIVE INFLUENCES ON SEX PARTNERSHIPS
The title of the Award is 'Estimating the Price Elasticities of Demand for Illicit Drugs'.  The purpose is understand how illicit drug users change their purchasing behavior when the price(s) of drugs changes.
Estimating the Price Elasticities of Demand for Illicit Drugs
We are developing an innovative Staying Safe Intervention based on the strategies and practices of long term IDUs who have managed to remain uninfected not only with HIV but also with Hepatitis C (HCV). This study will test the efficacy of such
Staying Safe: Training IDUs in Strategies to Avoid HIV and HCV Infection
This project will develop the chemical tools that will enable researchers to study certain proteins in the body to better understand their reactions to various chemicals and interactions with each other. By understanding these protein interacti
BIVALENT LIGANDS AS MOLECULAR PROBES FOR CB1/OX1 RECEPTOR HETERODIMERS
The global aim of this project, proposed under the R21 exploratory/developmental mechanism, is to examine the interplay between genetic factors for substance dependence and the age at onset of drinking or smoking, while advancing our understand
EARLY SUBSTANCE USE AND ADDICTION: GENES, ENVIRONMENT, AND EPIDEMIOLOGY
The development of tolerance to opioids limits their effectiveness for the treatment of pain. A wide variety of opioids that are commonly used in the clinic for the treatment of pain and drug addiction have dramatically different pharmacologica
AGONIST SELECTIVE ACTIVATION OF MU-OPIOID RECEPTORS
Injection drug use (IDU) is a major public health problem that is associated with a host of medical complications, including blood-borne viral disease (e.g., HIV, Hepatitis C) and bacterial infections (e.g., skin abscesses, endocarditis) that o
Reduction of Medical Complications associate with Injection Drug Use
This award is supporting a single project concerning drug abuse, risky decision-making and HIV/AIDS. In addition to the sharing of intravenous injection equipment, another major contribution of drug dependence to HIV risk involves the associati
SEXUAL HIV RISK BEHAVIOR AND IMPULSIVE DECISION MAKING IN COCAINE DEPENDENCE
The support cells of the olfactory epithelium have received little direct attention, yet several lines of evidence indicate that they are critical for maintaining or regulating the olfactory sensory nerve cells, the ongoing replacement of olfac
Young children with cleft lip and/or palate are at risk for speech and language delays associated with structural deficits despite early surgical repair. This study proposes to evaluate the effectiveness of an early intervention to facilitate s
An Exploratory Model of Early Speech Intervention for Children with Cleft Palate
This revised application is focused on the neural correlates of encoding and retrieving words in memory, with special focus on single-neuron responses to linguistic forms. While directly recording neural firing in human subjects as they perform
Representation of memory for spoken words and voice detail by single neurons
Brain function depends on precisely organized neural networks. A central problem in contemporary neuroscience has been to determine how the specific organization of synaptic inputs is established in the brain during development. Uncovering the
PROTEOMICS OF AUDITORY BRAINSTEM CIRCUITRY DURING DEVELOPMENT AND IN DEAFNESS
Title: Lysyl Oxidase Control of TGF-b in Bone Description, Purpose and expected outcome: Lysyl oxidase (LOX) is a copper-dependent amine oxidase that oxidizes primary amine of peptidyl lysine/hydroxylysine of collagen and elastin to initiate a
Renal Processing of Albumin (ARRA) 2.  Grant Title                     Renal Processing of Albumin (ARRA)    Description of project.    In 2003, I published a gel permeation/diffusion hypothesis (Smithies, 2003) postulating that the glomerular
DESCRIPTION (provided by applicant): Nephrotic Syndrome, characterized by massive proteinuria, hypoalbuminemia and edema, is one of the most frequently seen kidney diseases in children. Despite extensive research, the pathogenesis of this disea
Glucocorticoid Receptor Function in Steroid Resistant Childhood Nephrotic Syndrom
This project utilizes dietary data that was collected as part of the Boston Area Community Health (BACH) study to help fill knowledge gaps in the nutritional epidemiology of urogynecologic symptoms in a diverse, random community-based sample. L
Nutritional Epidemiology of Lower Urinary Tract Symptoms
We developed an analytical protocol to purify and enrich biotinylated histones from human cells for subsequent analysis by mass spectrometry. Our protocol is based on acid xtraction of bulk histones from Jurkat cells, followed by fractionation
Novel Histone Biotinylation Sites and Relationships to other Epigenetic Marks
Eukaryotic DNA is compacted through the formation of a nucleoprotein complex known as chromatin. The primary protein components of this complex are the core histones H2A, H2B, H3 and H4. The core histones form an octameric complex around which
(ARRA) Identification of histone modification interaction networks
Prescription drug sales have increased nearly 90% between 2000 and 2006, with further increases likely given the January 1, 2006 implementation of prescription drug benefits for seniors. Urologic symptoms are also on the increase; the projected
The metabolically obese normal weight (MONW) phenotype is a clustering of obesity-related metabolic disorders in persons with normal body mass index (BMI). Type 2 diabetes (T2DM) in normal weight persons is an intriguing representation of the M
Epidemiologic Studies of Type 2 Diabetes in Normal Weight Adults
Our laboratory recently observed that during early growth and development (6 weeks to 6 months), mice develop increasing susceptibility to diverse forms of acute renal damage.  Thus, whereas 1 month old mice are almost completely resistant to a
Characterizing the effects of Mouse Maturation on the Expression of Acute Renal F
DESCRIPTION (provided by applicant): Epithelial Na channels (ENaC) are expressed in the distal nephron where they serve as the final sites of Na reabsorption, thereby playing a key role in the regulation of extracellular fluid volume and blood
PHYSIOLOGIC ROLE OF THE GAMMA EPITHELIAL SODIUM CHANNEL SUBUNIT IN THE KIDNEY
DNA nanoparticles self assemble from plasmid DNA and CK30 covalently linked to polyethylene glycol, and effectively transfect airway epithelium, retina, and neurons, but how they access cells has been obscure. Recently the surface receptor for
Nucleolin-mediated cell entry of DNA nanoparticles
Phospholipase A2 (PLA2) are esterases that cleave glycerophospholipids, such as phosphatidylcholine, at the sn-2 ester bond, resulting in the release of a fatty acid and a lysophospholipid. Recent studies demonstrate that PLA2 expression and ac
Spla2 Selective Degradation of Nanoparticles
College of Pharmacy, PS336 RC Wilson Building
College of Pharmacy, 220 RC Wilson Building
Miniaturization is a growing trend for bioanalytical instruments. Integration of sensing, detection, and manipulation functionalities in a small space promises a new generation of inexpensive, portable and highly sensitive equipment that can be
INTEGRATED OPTICAL PARTICLE TRAP FOR BIOMOLECULE ANALYSIS AND MANIPULATION
identification of excitatory and multiple types of inhibitory neurons, will enable simultaneous calcium imaging from multiple identified cell types with no need in additional promoter- specific genetic labeling. This approach will significantl
TWO-PHOTON CALCIUM IMAGING OF SPECIFIC NEURONAL PHENOTYPES
The long-term objective of this work is to develop predictable and reproducible therapies for soft tissue regeneration using adipose stem cells (ASCs) formulated as 3-dimensional (3-D) multicellular aggregates. Currently available treatments ar
A Modular Niche-Based Approach to Soft Tissue Regeneration
This project is being supported with funds from the American Recovery and Reinvestment Act, which may involve a reduction in the research aims and scope. If necessary, a revised abstract will be posted soon and this notice removed.  DESCRIPTION
ARRA Functional Magnetic Resonance Angiography (fMRA) of the Brain
Apoptosis, 'programmed cell death,' is a cellular process exhibiting distinct biochemical and morphological changes, and is a key element of both normal and disease processes at the cellular level. As such, apoptosis is the subject of thousands
INSTRUMENTATION FOR OPTICAL MONITORING OF APOPTOSIS IN UNLABELED CELL CULTURES
The rising resistance of bacteria to antibiotics has been referred to by the Centers for Disease Control and Prevention (CDC) as “one of the world's most pressing health problems.” The need for rapid antibiotic susceptibility tests is becom
ULTRA RAPID MONITORING OF BACTERIAL NANO-GROWTH AND ANTIBIOTIC SUSCEPTIBILITY
Modulation of conjunctival goblet cell differentiation by immunoregulatory cells: This project will investigate the role of local immunoregulatory pathways on conjunctival epithelial homeostasis and the response of the conjunctival epithelium t
Modulation of conjunctival goblet cell differentiation by immunoregulatory cells
Antisocial Behavior, Genetics, & the Life Course (1R21-HD050261-01A2) The purpose of this research is to integrate genetic & life course models of criminal & otherwise antisocial behaviors from adolescence to young adulthood. Data come from fou
Antisocial Behavior, Genetics, and the Life Course
'We are developing a casual game played on a cell phone to teach effective food parenting practices using simulated parent-child interaction sequences with feedback and goal setting.
Training Effective Vegetable Parenting Skills
American children from ethnic minority and low socioeconomic families have higher rates of poor health and higher mortality rates. Recent data suggest persistence or widening of these ethnic and socioeconomic differentials in health outcomes of
Trends in Ethnic and Socioeconomic Differentials in Diet Quality in American Children
EDUCATION, TRAINING, AND RESEARCH ASSOCIATES
The purpose of the study is to tackle the disparities among African American youth disproportionately affected by HIV/AIDS and other sexually transmitted infections by developing and testing a new intervention approach that addresses sexual ris
New HIV Intervention Approaches for African American Youth
To address whether small molecules can be identified that inhibit differentiation of hESCs in the absence of growth factors/cytokines for long-term self-renewal of hESCs (in a way conceptually similar to the function/mechanism of pluripotin in
SMALL MOLECULES THAT MAINTAIN SELF-RENEWAL OF HESCS WITHOUT GROWTH FACTORS
In the last decade, significant advances have been made toward achieving chemical control of key developmental signal transduction pathways that are frequently corrupted in cancer. Given the promise of these therapeutic strategies and the peril
Chemical Disruption of Hh and Wnt Pathways in Vertebrate Development (MPI) - ARRA Stimulus 2 Yr Resub
The goal of the proposed research is to examine the relationship between socioeconomic status (SES), socioeconomic instability and overweight among young children of immigrants and children of natives. This topic is significant because over one
Demographic Analysis of SES Stability & Well-Being Amoung Chilldren of Immigrants
DESCRIPTION (provided by applicant): Cleft palate is a highly prevalent craniofacial malformation that affects approximately one in 700 newborns in the U.S. Studies on small numbers of children have raised the concern that repair of the cleft p
Sleep and Neurobehavioral Performance After Cleft Palate Repair
Atrial fibrillation (AF) is the commonest rhythm disturbance of the heart, and is a major cause of serious morbidity such as congestive heart failure and cerebrovascular embolism (`stroke'). More recently, AF has been found to be associated wit
Disruption of Autonomic Pathway in the Left Atrium by Inhibition of G-Proteins
As a systemic disease of the vessel wall, atherosclerosis occurs in carotid, coronary and peripheral arteries, and has contributes to significant morbidity and mortality in the adult population. Recent advances in basic sciences have establishe
Cardiovascular Inflammation Function Imaging By Photoacoustics Using Gold
Large epidemiological studies have indicated that genetic factors contribute significantly to the development of coronary atherosclerosis, a major cause of morbidity and mortality in Western countries. Through genome-wide association studies (G
In Vivo Analysis of a Noncoding Susceptibility Region for Coronary Artery Disease
To support research and other projects that will support fundamental biomedical discovery and translation of that knowledge into effective prevention strategies and new treatments while also providing economic stimulus to the nation.
A new informatic paradigm for reconstructing signaling pathways in human disease
Mouse models of human psychiatric disorders show that chronic stress can lead to depression. Mice lacking 5HT2CR show signs of stress response, hyperactivity, increased appetite and obesity. 5HT2CR mRNA is edited by two enzymes ADAR1 and ADAR2
RNA Editing in a Transgenic Mouse Model of Behavioral Despair and Anxiety
HIPPOCAMPAL PLASTICITY IN CO-MORBID DIABETES AND DEPRESSION There is a growing appreciation that the complications of diabetes extend to the central nervous system (CNS), including structural and functional deficits in the hippocampus. Deficits
HIPPOCAMPAL PLASTICITY IN CO-MORBID DIABETES AND DEPRESSION
NAME:  Timely End-of-Life Communication to Parents of Children with Brain Tumors. DESCRIPTION:  Having a child diagnosed with a cancer that has a poor prognosis is a highly stressful situation and one in which parents need to make very difficul
Timely End-of-Life Communication to Parents of Children with Brain Tumors
Increasing numbers of hospice patients are admitted with heart failure as a primary diagnosis. Hospice provides comprehensive palliative care for both patients and their family members, but family caregivers often have unmet needs, even when re
PILOT OF AN INTERVENTION FOR CAREGIVERS OF HOSPICE HF PATIENTS
DESCRIPTION (provided by applicant): We propose an innovative project that will identify and examine the compensatory strategies and resources used by low literate and low health-literate Latino diabetes patients when faced with literacy-demand
LITERACY- COMPENSATORY STRATEGIES AND RESOURCES OF OLDER LATINOS WITH DIABETES
Amyotrophic lateral sclerosis (ALS) is an enigmatic, horrific illness with a rapid course of progression for which there is little in the way of effective therapy. Finding objective markers for the progression of the disease is crucial for asse
Functional and Chemical Markers for ALS Progression
Title: Reconstruction and Mapping of Human Brain Vasculature Description: This project aims at building digital reconstructions of the brain arterial network from magnetic resonance image data, characterizing the arterial morphometry, and const
Reconstruction and Mapping of Human Brain Vasculature
Parkinson's disease (PD) is a devastating neurodegenerative movement disorder characterized by a loss of dopamine-containing neurons of substantia nigra, which currently affects about 1.5 million people in the United States. While the causes of
Activators of Nrf2/ARE pathway as a therapeutic target for Parkinson's disease
Lafora disease (LD) is an autosomal recessive and incurable disease with characters of progressive myoclonus epilepsy (PME), severe neurological deterioration, and the accumulation of starch-like glycogen inclusion bodies (LB) mainly in the bra
MOLECULAR PATHOLOGICAL MECHANISM & POTENTIAL THERAPEUTICS OF LAFORA DISEASE
This  proposal  plans  to  develop  a  technique  that  will  permit  the  selective  activation  of individual subtypes of neurons by expressing in specific types of neurons genes of proteins that are capable of depolarizing only those neurons
Heterologous expression of an invertebrate sodium channel for neuronal activation
Central nervous system (CNS) diseases and disorders represent the largest and fastest growing area of unmet medical need. Over 1.5 billion people worldwide, including over 100 million people in the US, suffer from CNS diseases or disorders. Thi
Brain-targeted nanomedicine via buccal administration
Amyotrophic lateral sclerosis (ALS) is characterized by the progressive and selective loss of motor neurons (MNs) in the motor cortex, brainstem, and spinal cord, resulting in death of patients 2-5 years after diagnosis. Glutamate-mediated exci
Targeting AMPA Receptor Splicing as a Therapeutic Approach for ALS
A wide array of inherited human diseases are caused by mutations in our mitochondrial DNA (mtDNA) genome and in mitochondrial genes encoded in the nuclear genome, but there are currently no effective therapies for these clinically devastating d
Towards gene therapy of mitochondrial disease
'Apoptosis is an orderly process of cellular elimination, which ensures complete disassembly and disappearance of damaged cells. Recently the concept of apoptotic cell elimination was expanded and programmed cell death is no longer viewed as an
The multi-gene family of proteins called connexins form intercellular gap junctions that directly mediate signaling between adjacent cells. These cell-cell channels consist of two hemichannels or so-called connexons from adjacent cells. In addi
ARRA: Pharmacology of Connexin Channels Structure-Activity Studies
MAYO CLINIC JACKSONVILLE (A NONPROFIT CORPORATIO
Parkinson's disease (PD) is a prevalent, heterogeneous disorder with a complex, multifactorial etiology. The syndrome affects multiple systems with motor and non-motor features. In the past decade, many genes and specific mutations contributing
Genotype/Phenotype Studies of Parkinson's Disease in Tunisia
Amyotrophic lateral sclerosis is an adult onset motoneuron degenerative disease with a lifetime risk of ~1/1000 that affects an estimated 30, 000 adults in the US at any one time with ~5000 new cases/year. Approximately 80% of the cases are fat
(ARRA) Development of a zebrafish assay for the identification of ALS drug targets
The award title is “Role of NCKX2 in the activation of toxic Zn2+ influx in ischemic neurons.” Our ultimate goal is to improve the safety of cardiac surgeries that involve cardiopulmonary bypass. Over 700,000 such surgeries are performed in
Role of NCKX2 in the Activation of Toxic Zn2 Influx in Ischemic Neurons
unique to each LSD. Here, we propose to: 1) test the hypothesis that exosomes from human disease cells have unique protein and/or lipid identifiers that will distinguish them from those of normal cells and reveal alterations of specific metabo
METABOLOMICS OF THE ENDOSOMAL/LYSOSOMAL SYSTEM
Translational grant to develop and test a fusion protein as a potential therapeutic for Myotonic dystrophy. Generation of the protein fusion will be followed by testing its activity in cell lines from human patients, ultimately testing its effi
Intravenous Protein Therapy for Myotonic Dystrophy Type 1
Parkinson disease (PD) is caused by a progressive loss of the dopamine (DA) neurons in the substantia nigra pars compacta (SNc). Although the etiology of PD is still unknown, there is increasing evidence that it is a complex disorder influenced
miRNAs as regulators of gene expression in Parkinson Disease
The ubiquitin E3 ligase Ube3a has been implicated in two severe neurological disorders, Angelman's syndrome (AS) and autism spectrum disorder caused by maternal 15q 11-13 duplication (15qASD). Cells from 15qASD and AS patients have excess and d
NEUROBIOLOGICAL MECHANISM OF 15Q11-13 DUPLICATION AUTISM SPECTRUM DISORDER
This proposal, combining established biomedical engineering and clinical expertise from two institutions, seeks to develop and validate a portable, spatially-modulated imaging system with the long term goal of intra-operatively assessing surgic
A spatially-modulated scatter imaging system to detect tumor-associated stroma
UNIVERSITY ENTERPRISES CORPORATION AT CSUSB
The overall goal of the proposed California State University, San Bernardino (CSUSB) Minority Drug Abuse Research Program (MIDARP) is to increase the quality and quantity of research on the CSUSB campus focused on drug abuse and addiction, part
CSUSB Minority Drug Abuse Research program
Chronic disease is a major contributor to health disparities, and complex chronic disease (multiple chronic conditions requiring multiple providers) is increasingly common. Literature suggests that individuals with chronic disease receive less
ARRA: Cancer Prevention among Urban Poor with Complex Chronic Conditions
American Recovery and Reinvestment Act Port Secuirty Grant Program (ARRA PSGP)
Bainbridge Island Police Department Marine Unit NetCentric Project
American Recovery and Reinvestment Act Port Security Grant Program
American Recovery and Reinvestment Act Port Security Grant Program (ARRAPSGP)
BRIDGEPORT & PORT JEFFERSON STEAMBOAT COMPANY INC
Coastal and Great Lakes Passenger Transportation
Scenic and Sightseeing Transportation, Water
AMERICAN RECOVERY and REINVESTMENT ACT PORT SECURITY GRANT PROGRAM (ARRA PSGP)
Port Security Grant Program - Perimeter Security Fencing / Personal Protective Equipment
American Recovery and Reinvestment Act Port Security Grant Program (ARRA PSGP).
FISH & WILDLIFE CONSERVATION COMMISSION, FLORIDA
American Recovery and Reinvestment Act, Port Security Grant Program (ARRA_PSGP) 0398
NATURAL RESOURCES, INDIANA DEPARTMENT OF
American Recoveryand Reinvestment Act Port Security Grant Program (ARRA PSGP)
The COPS Hiring Recovery Program (CHRP) provides funding directl to law enforcement agencies to hire and/or rehire career law enforcement officers in an effort to create and preserve jobs, and increase their community policing capacity and crim
The COPS Hiring Recovery Program (CHRP) provides funding directly to law enforcement agencies to hire and/or rehire career law enforcement officers in an effort to create and preserve jobs, and to increase their community policing capacity and
The COPS Hiring Recovery Program (CHRP) provides funding directly to law enforcement agencies to hire and/or rehire career law enforcement officers in an effort to create and preserve jobs and to increase their community policing capacity and c
The funding under this project is for the payment of approved full-time entry level sworn officer salaries and fringe benefits over 3 years (for a total of 36 months of funding) for new or rehired additional, career law enforcement officer posi
COPS - Community Oriented Policing Services
The COPS Hiring Recovery program (CHRP) provides funding directly to law enforcement agencies to hire and/or rehire career law enforcement officers in an effort to create and preserve jobs, and to increase their community policing capacity and
City of Omaha COPS Hiring Recovery Program (CHRP)
The COPS Hiring Recovery Program (CHRP)provides funding directly to law enforcement agencies to hire and or rehire career law enforcement officers in an effort to create and preserve jobs, and to increase their community policing capacity and c
The COPS  Hiring Recovery Program (CHRP) provides funding directly to law enforcement agencies to hire and/or rehire career law enforcement officers in an effort to create and preserve jobs, and to increase their community policing capacity and
The COPS Hiring Recovery Program (CHRP) provides funding directly to law enforcement officers in an effort to create and preserve jobs, and to increase their community policing capacity and crime prevention efforts.
The COPS Hiring Recovery Program (CHRP) provides funding directly to law enforcement agencies to hire and/or rehire career law enforcement officers in an effort to create and preserve jobs and increase their community policing capacity and crim
The COPS Hiring Recovery Program (CHRP) provides funding directly to law enforcement agencies to hire and/or rehire career law enforcement.
The cops hiring recovery program (CHRP) provides funding directly to law enforcement agencies to hire and/or rehire career law enforcement officers in an effort to create and preserve jobs and to increase their community policing efforts.
The COPS Hiring Recovery Program (CHRP) provides funding directly to law enforcement agencies to hire and/or rehire career law enforcement officers in an effort to create and preserve jobs, and to increase their communtity policing capacity and
The COPS Hiring Recovery Program (CHRP) provides funding dir3ectly to law enforcement aganecies to hire and/or rehire career law enforcement officers in an effort to create and preserve jobs, and to increase their community policing capacity an
The CHRP provides funding directly to law enforcement agencies to hire new and or/rehire career law enforcement personnel.
The COPS Hiring Recovery Program (CHRP) provides funding directly to law enforcement agencies to hire and/or rehire career law enforcement officers in an effort to create and preserve job, and to increase their community policing capacity and c
The COPS Hiring Recovery Program (CHRP) provides funding directly to law enforcement agencies to hire and/or rehire career law enforcement officers.
The COPS Hiring Recovery Program (CHRP) provides funding directly to law enforcement agencies to hire and/or rehire career law enforcement officer in an effort to create and preserve jobs, and to increase their community policing capacity and c
The Cops Hiring Recovery Program (CHRP)provides funding directly to law enforcement agencies to hire and/or rehire career law enforcement officers in an effort to create and preserve jobs, and increase their community policing capacity and crim
Funding is to be used to hire 14 new officers for community policing.
Macon Police Department Cops Hiring Program
CHRP provided funding for the hiring of two law enforcement officers in an effort to create jobs and to increase our capacity for community policing.
The COPS Hiring Recovery Program (CHRP) provides funding directly to law enforcment agencies to hire and/or rehire career law enforcement officers in an effort to create and preserve jobs, and to increase their community policing capacity and c
CHRP Award for Hiring two additional Police Officers  at the Markham Police Department in Markham, Illinois.
'The COPS Hiring Recovery Program'(CHRP)provides funding direcly to law enforcement agencies to hire and/or rehire career law enforsement officers in an effort to create and preserve jobs, and to increase their community policing capacity and c
The COPS Hiring and Recovery Program (CHRP) provides funding directly to law enforcement agencies to hire and/or rehire career law enforceement officers in an effort to create and preserve jobs, and to increase thier community policing capacity
Hopkinsville Police Department Hiring Recovery Program
THE COPS HIRING RECOVERY PROGRAM (CHRP) PROVIDES FUNDING DIRECTLY TO LAW ENFORCEMENT AGENCIES TO HIRE AND/OR REHIRE CAREER LAW ENFORCEMENT OFFICERS IN AN EFFORT TO CREATE AND PRESERVE JOBS, AND TO INCREASE THEIR COMMUNITY POLICING CAPACITY AND
The COPS Hiring Program (CHRP) provides funding directly to law enforcement officers in an effort create and preserve jobs, and to increase their community prevention efforts
The COPS Hiring Recovery Program provides funding directly to law enforcement agencies to hire and/or rehire full-time career law enforcement officers
LAC VIEUX DESERT BAND OF LAKE SUPERIOR CHIPPEWA INDIANS
The COPS Hiring Recovery Program provides funding directly to law enforcement agencies to hire and/or rehire career law enforcement officers in an effort to create and preserve jobs, and to increase their community policing capacity and crime p
COPS Hiring Recovery Program (CHRP) provides funding directly to law enforcement agencies to hire and/or rehire career law enforcement officers in an effort to create and preserve jobs, and to increase their community policing capacity and crim
The COPS Hiring Recovery Grant Program (CHRP) provides funding directly to law enforcement agencies to hire and/or rehire career law enforcement officers in an effort to create and preserve jobs, and to increase their community policing capacit
DESCRIPTION (provided by applicant): Basophils are now recognized as critical effectors and immune modulators during Th2 mediated immune responses, such as allergic inflammations and parasite infections. Evidence suggests that basophils produce
MECHANISM OF BASOPHIL MEDIATED IMMUNE MODULATION
Hantaviruses infect endothelial cells (ECs) and cause 2 vascular permeability-based diseases: Hemorrhagic Fever with Renal Syndrome (HFRS) and Hantavirus Pulmonary Syndrome (HPS). Pathogenic hantaviruses bind to a 53 residue PSI domain present
ARRA:  Determinants of Pathogenic Hantavirus Attachment
Human noroviruses (HuNoVs) are the leading cause of gastroenteritis worldwide causing 23 million cases of gastroenteritis annually and substantial economic impacts in the US alone. The lack of an animal disease model (until recently) and routin
(ARRA) Breakthroughs to advance the in vitro propagation of human noroviruses
This proposal will use the interferon-gamma binding protein from ectromelia virus (IFN-gBPECTV) to design new cytokine antagonists and improved research reagents with broad applications to many disciplines.  Preliminary structural studies on IF
STRUCTURE AND DESIGN OF CYTOKINE AND CHEMOKINE BINDING PROTEINS
Schistosomiasis is an important tropical parasitic human disease. Although an effective anti-schistosome drug is in use, it is estimated that 200 million people are infected, 20 million individuals suffer severe disease symptoms, and 280,000 pe
Is Phytochelatin Synthase an Essential Enzyme and Drug Target for Schistosomiasis
Sjögren's syndrome (SjS) is a systemic autoimmune disease characterized primarily by salivary and lacrimal gland dysfunction.  As with many autoimmune connective tissue diseases, there exists a sexual dimorphism in SjS with women affected 10-
Gene Therapy Targeting the Th17 / IL-27 System in Autoimmune Exocrinopathy
Herpes simplex virus-1 (HSV-1) is human alphaherpesvirus that establishes a lifelong latent infection in peripheral nerve ganglia following primary infection. HSV-1 infections are generally benign, although its capacity for neurovirulence and n
Investigation of herpes simplex virus -1 neurotropism in SCID DRG xenografts
Bacillus anthracis is the bacterium that causes the disease anthrax. Concern over its use as a bioweapon has renewed interest in elucidating mechanisms of how it causes disease. B. anthracis promotes its growth in the host through the productio
In vivo effects of anthrax toxins:imaging host response & bacterial proliferation
Information gleaned from recent studies with single-stranded, positive-sense RNA viruses pathogenic to humans and animals (polio and alphaviruses) and insects (flock house virus; FHV) revealed that the mechanism of genome packaging in these vir
Interconnectivity Between Genome Packaging and Other Viral Functions
Immunoreceptor-mediated activation of transcription factor NF-kB and MAP kinases (MAPKs) is essential for proper regulation of multiple genes involved in the innate and adaptive immune response to microbial pathogens. Prior experiments with tra
In Vivo Function of Traf6 as a Target of K63-Linked Polyubiquitination
Schistosomiasis is a major tropical disease caused by parasitic flatworms called schistosomes. Although there is an effective drug against schistosomiasis, the mechanism by which it works is unclear. By understanding that mechanism, it may be p
Transformation of C. elegans with a novel schistosome calcium channel subunit
The filoviruses, Ebola (EBOV) and Marburg (MARV), cause periodic hemorrhagic fever outbreaks in sub-Saharan Africa.  Because of the high rates of mortality associated with these infections and high transmissibility of these viruses in the huma
Selection of RNA Aptamers Against Ebola Virus GP2
Tuberculosis is a leading health problem worldwide. Mycobacterium tuberculosis virulence is based on its capability to reside inside macrophages.  At the center of its pathogenic strategy is the handling of involved heavy metals (Cu+, Zn2+, Fe2
Mycobacterium Tuberculosis Metal Transport P-Type AT Pases
AKT, a phosphatidylinositol 3-kinase (PI3K)-dependent serine-threonine kinase, promotes glucose metabolism and survival of activated T cells and limits differentiation of regulatory T cells (Tregs). While AKT is critical for thymocyte developme
Peripheral T Cell tolerance by targeting AKT
patients have more favorable outcomes, with lower incidence of cirrhosis and hepatocellular carcinoma (HCC). The association of HBeAg seroconversion with better outcome may be due to its association with reduction in HBV viral load as HBV DNA
AIDS Clinical Trials Group Longitudinal Linked Randomized Trials (ALLRT) Protocol receiving mono or dual HBV therapy
T helper cells in lymphoid tissues adopt multiple cell fates that regulate inflammation. At the G-I mucosa, their dominant phenotype is of Treg cells. Mucosal adjuvants, by overriding the tolerant impact of mucosal Treg cells, are unique tools
MUCOSAL ADJUVANTS REGULATE INFLAMMATION AND IMMUNITY
Human coronaviruses (HCoVs) are positive-stranded RNA viruses that are estimated to account for approximately 30% of cases of the common cold. The emergence of a novel HCoV as the etiologic agent of severe acute respiratory syndrome (SARS) demo
This study will define mucosal virulence and mechanism of innate immune host defense against aerosolized Rift Valley fever virus, a Category A biodefense pathogen. Rift Valley Fever virus (RVFV) is designated a priority pathogen based upon its
Mucosal Innate Immune defense to Rift Valley Fever Virus
Giardia lamblia is a common cause of intestinal infections. We propose to screen large collections of small molecules to identify new leads for future development of drugs against this parasite.
High Throughput Screening for new inhibitors of Giardia Lamblia
Trypanosomatids are protozoan hemoflagellates responsible for a variety of human diseases, including Chagas' disease, leishmaniasis, and African sleeping sickness, which account for nearly one million deaths per year. The unique genetic phenome
Functions of Nuclear Non-Canonical Poly(A) Polymerases in Trypanosomes
In light of the extreme mortality rates associated with human infection with avian influenza strains, the emergence of a pandemic influenza outbreak is of immense concern.  Pandemic strains are thought to occur through the introduction of genet
Predicting Protein Evolution with Phage Escape
In humans, IL4 and TH2 cells critically impact a wide array of diseases, a prime example of which is bronchial asthma where genetic association studies have repeatedly identified both the gene locus encoding IL4 and IL13 (5q25-31) and several m
The specific hypothesis behind the proposed research is that the prion agent can be shed from olfactory neurons into nasal secretions and the amount of prion infectivity released into nasal secretions will be enhanced under conditions that prom
Role of Viral Infection in Prion Shedding
Clinical data support the concept that both normal stem cells and leukemia stem cells exhibit multiple drug resistance. However, it is unclear how mechanisms for drug resistance might interrelate with stem cell physiology. Our preliminary studi
EXPLORING THE PHYSIOLOGY OF LEUKEMIC STEM CELLS BY MECHANISMS OF DRUG RESISTANCE
The purpose of this study is to develop and test the feasibility of using individually tailored theoretically-based intervention strategies to promote mammpgraphy screening among non-adherent Chinese-American women.
An Individually-Tailored Mammography Screening Intervention for Chinese Americans
Median survival from a hepatocellular cancer (HCC) diagnosis is only 8 months; therefore, effective prevention strategies are a high priority. Due to the epidemic of hepatitis C in the 1960’s-70’s, incidence has increased; approximately 3.2
Retinoid and Carotenoid Depletion in Patients at High Risk for Liver Cancer
Prostate cancer is the most commonly diagnosed noncutaneous cancer in United States men and the second leading cause of cancer death. It is estimated that 186,320 men will be diagnosed with prostate cancer in 2008 and 28,660 men will die of it.
Prostate cancer health literacy in rural versus urban African-American men
With completion of the genome sequence and the estimated 20-25,000 genes comprising its entirety, it has become clear to investigators that the complexity of humans cannot be fully explained by so few genes. Alternative splicing of mRNA provide
DIFFERENTIATING TUMOR CLASSES BY ANALYSIS OF ALTERNATIVE SPLICE VARIANT PATTERNS
Children with unfavorable histology Wilms tumor (WT) and metastatic disease continue to experience high mortality rates. These patients urgently require new therapies. We have recently reported Phase I data indicating excellent tolerance of the
Combined Ultrasound/Molecular Analysis of Tumor Response to VEGF Blockade
Today’s medical imaging methods have insufficient specificity for reliable differentiation between benign and malignant breast lesions in patients. Pathologic evaluation is currently the only way to obtain a definitive diagnosis. This researc
Many types of cancer exist in the body in environments that are highly acidic (low pH) compared with normal healthy tissue.  This increase is acidity is believed to contribute to cancer progression and its resistance to therapy.  For these reas
Recently, there has been an increased interest in 'individualized medicine' and thus pharmacogenetics and pharmacogenomics in cancer research have moved to the forefront as well. Pharmacogenetics is the study of the role of inheritance in indiv
Integrative genomic models for analysis of pharmacogenomic studies.
The chance of developing invasive breast cancer during a woman's lifetime is approximately 1 in 8 and more that 40,000 women die of metastatic disease each year. Inherent or acquired tumor drug resistance and dose-limiting toxicity limit many a
MITOCHONDRIAL CATALASE AS A TREATMENT FOR METASTATIC BREAST CANCER
Protein kinases are widely implicated in human disease, especially in cancer, and play a fundamental role in human biology. In order to understand the so-called 'phospho-proteome' one needs new tools to address which particular kinase(s) are ac
Kinase selective small molecule conjugates as antibody surrogates
Prostate cancer, a leading cause of cancer related deaths among men in the United States, is usually diagnosed in the sixth or seventh decades of life, which allows a large window of opportunity for intervention to prevent or slow progression o
Prostate Cancer Prevention by Commiphora Mukul Extract
SCHEPENS EYE RESEARCH INSTITUTE, INC., THE
The overall goal of the research is to test the hypothesis that fibroblast growth factor 15 (FGF15) is a key signal regulating the transition from neurogenesis to gliogenesis in the developing cortex and that drugs of abuse may alter FGF15 sign
Glial Modulation of Cortical Development and Drug of Abuse-induced Brain Damage
The main goals of our parent grant (R01AA10788) are to test in alcohol dependent individuals (i) if chronic smoking influences brain injury, (ii) if chronic smoking effects ares functionally significant, and (iii) to what extent chronic smoking
Polysubstance Use and Chronic Smoking: Neuroimaging and Cognition
Addiction is a potent risk factor for suicide and suicidal behavior. Although suicide is 5 to more than 100 times more frequent among people with addiction disorders, and even higher among people in addiction treatment, no suicide prevention ef
A recent imaging study suggested that damage to the insular cortex (IC) results in cessation of smoking in chronic cigarette users. However, the regions of interest designated as the IC in this imaging study included not only the IC but also t
The Role of Claustrium in Stubstance Abuse and Cognition
All neurotransmitters require an efficient mechanism to terminate their action. Water-soluble neurotransmitters diffuse unassisted in the cytosol to their respective catabolic enzyme for breakdown, after being transported into cells. The endoca
Synapses are specialized sites of cell-cell contact that mediate communication between neurons in the nervous system. Much remains to be discovered about the molecular mechanisms that underlie formation of these critical structures in the mamma
Identification of the Protein Kinases which Regulate Mammalian Synapse Formation
Smoking tobacco remains the top preventable cause of disease and death in our society. Nicotine withdrawal is a major contributor to the persistent nature of tobacco use, as well as the frequent occurrence of relapse following attempts at smoki
Genetic Moderation of Attentional Deficits Resulting from Nicotine Withdrawal
DESCRIPTION (provided by applicant): Cocaine addiction is a serious problem afflicting the United States, and treatment remains imperfect. Although the study of cocaine self-administration and reinstatement in rats has provided much knowledge o
Infralimbic Cortex Regulation of Memory Consolidation of Extinction of Cocaine Self-Administration
Quantitative, acoustic models of segmental timing in spoken English, such as have been developed for text-to-speech synthesis (TTS), acknowledge that segment durations in connected speech reflect the combined influence of systematic factors as
QUANTITATIVE MODELING OF SEGMENTAL TIMING IN DYSARTHRIA
We have identified a novel peptide that acts as an effective therapeutic agent in mouse and hamster models of radiation-induced oral mucositis by targeting tight junctions (TJs) that connect adjacent epithelial cells, thereby protecting the muc
TARGETING TIGHT JUNCTIONS TO TREAT MUCOSITIS
The morphology of a dental crown is controlled by a strictly regulated spatio-temporal expression of ameloblast specific genes encoding for enamel matrix proteins. Once ameloblasts enter the differentiation stage along the dentino-enamel juncti
DEVELOPMENTAL DYNAMICS OF ENAMEL FORMATION
Removal of regional metastasis in head and neck squamous cell carcinoma (HNSCC) requires an extensive procedure with significant morbidity. Current imaging techniques cannot provide real-time information to clinicians or surgeons during diagnos
FLUORESCENTLY LABELED ANTI-EGFR TO GUIDE REMOVAL OF LYMPH NODE METASTASIS
Most dialysis patients in the US are >65 years and are at increased cardiovascular risk. The prevalence of atrial fibrillation (AF) is higher in dialysis patients, but estimates vary widely (7%-27%). Further, controversy persists in defining it
Warfarin Use in ESRD Patients with Atrial Fibrillation:  Risks, Benefits, Behavior
. Studies are needed to determine the prevalence of ASB and the host characteristics, bacterial virulence factors and consequences associated with ABU in the renal transplant patient.
ASYMPTOMATIC BACTERIURIA & RISK OF URINARY TRACT INFECTION IN RELA TRANSPLANTS
Despite extensive research, the etiology of Crohn's inflammatory bowel disease remains unknown with possible suggestions attributed to genetic susceptibility, infectious agents, immune dysfunction, and various environmental agents. A number of
S-NITROSOGLUTATHIONE REGULATION OF INTESTINAL BARRIER FUNCTION IN CROHN'S DISEASE.
DESCRIPTION (provided by applicant): Linking home environments and primary care: Obesity prevention for 2-4 year olds. Obesity prevention for at-risk preschool children is a public health priority. The pediatric primary care setting is a relati
Linking home environments and primary care:  Obesity prevention for 2-5 year olds
Obesity and type 2 diabetes share several metabolic abnormalities, including an impaired ability of cells to sense increased nutrients flux. Since the brain plays a crucial role in regulating the homeostasis of fuel metabolism and body weight,
Regulated Expression of Hypothalamic CPT1 using Gutless Adenovirus
Over 7 million people in the U.S. suffer from chronic kidney disease and about half a million will await kidney replacement therapy.  It is believed that the oxygen availability within the kidney may be an important determinant of the progressi
The Intra-renal Oxygenation in CKD as evaluated by BOLD MRI
The long term goal of our research is to investigate the role of smooth muscle myosin heavy chain (SMHC) isoforms in urinary bladder smooth muscle (SM) physiology and pathology. We have shown previously that alternative splicing of a single SMH
(ARRA) Myosin isoforms in urinary bladder function
Good glycemic control, lipid control, or blood pressure (BP) control can be achieved by adherence to recommended care, including medication, preventive care, and lifestyle modifications. Good physiologic control, in turn, attenuates risk of pro
Psychosocial Effects on Patient Adherence, Allostatic Load, and Chronic Disease
The sterol response element binding protein (SREBP) transcription factors have been identified as key regulators of genes involved in both cholesterol and lipid homeostasis. Because of the prominence of aberrant cholesterol and lipid homeostasi
Role of MicroRNA mi R-33 in Controlling Cholesterol/Lipid Homeostasis
bioanalytical applications, including biological imaging.  Ultimately, these nanoparticles will constitute a versatile luminescence platform whose optical properties will complement existing fluorophores, their signal being easily discriminate
Numerous studies have shown associations of ambient particulate matter (PM) air pollution with cardiovascular hospital admissions and mortality. The causal pollutant components and physiologic mechanisms for these associations are not fully und
Air Pollution and Peripheral Blood Gene Expression in Subjects with Coronary Artery Disease
This application is a new investigator-initiated (NIEHS PA-06-181) exploratory/developmental research grant (R21) that addresses the need for understanding the impact of long-term ambient air pollution exposure on a therogenesis. Ambient air po
Air Pollution, Systemic Inflammation, and Sub-Clinical Atherosclerosis in High-Altitude Children
Preliminary evidence suggests that exposure to air pollution may be related to cognitive decline, particularly among older women, and our project evaluates this relation in a large population of older women.  Since exposure to air pollution is
Air Pollution and Cognitive Aging Among Older Women
Lung adenocarcinoma is among the deadliest cancer types world-wide. Solid tumors such as these almost universally acquire adaptive changes to survive hypoxic energy stress. This confers an increase in aggressiveness and resistance to chemothera
ADSS1 INACTIVATION AS A PROMOTER OF TUMOR METABOLISM  AND LUNG CARCINOGENESIS
Recent research suggests that obesity and diet induce inflammation in adipose tissue, which may enhance the development of type 2 diabetes mellitus (T2DM) and insulin resistance (IR). Epidemiological studies have demonstrated that exposure to a
(ARRA) Obesity development: role of air pollution and high fat diet
DESCRIPTION: Osteoporosis is a serious health concern of the elderly that is expected to become more prevalent as the US population ages. Like many complex physiological systems, bone biology is dependent on both genetic factors and environment
Diet by Gene Interactions Affecting Calcium and Bone Metabolism
Phototransduction in retinal rods relies on signaling mediated by the heterotrimeric G-protein transducin. We investigate the involvement of the transducin beta-gamma complex in visual signal propagation and amplification, as well as in the mor
G-proteins and mechanisms of signal transduction in vision
Cited2 (CBP/p300-interacting transactivators with glutamic acid (E) and aspartic acid (D)-rich tail 2) is a founding member of a new family of transcriptional modulators. My laboratory cloned Cited2 and showed that Cited2 is induced by many bio
Role of Cited 2 in Lens Development and Hyaloid Vascular Regression
Corneal endothelial cell dysfunction causes decreased vision and can only be treated by corneal transplantation to replace human corneal endothelial cells (HCECs), which do not proliferate in vivo. Over 15,000 corneal transplants are performed
DESCRIPTION (provided by applicant): The hyaloid vascular system (HVS) is a transient vascular network that nourishes the immature lens and retina before formation of the retinal vasculature. Defects in HVS development can lead to serious conge
RETINA-DERIVED SIGNALS REGULATING DEVELOPMENT OF THE VITREOUS HYALOID VASCULATURE
Cone photoreceptors function under daylight conditions and are essential for color perception and vision with high temporal and spatial resolution. A remarkable feature of cones is their ability to remain functional in bright light which requir
CALCIUM AND ADAPTATION IN MAMMALIAN CONE PHOTORECEPTORS
Causal Estimates of Neighborhood Poverty on Health & Mortality Project Summary Abstract The disparities in the distribution of goods and services, and hazards and opportunities across space are increasing, underscoring the growing connection be
Causal Estimates of Neighborhood Poverty on Health & Mortality
In most species, including humans, plasma levels of 17ß-estradiol and progesterone increase during pregnancy. The elevation of female hormones that accompanies the late stages of pregnancy has been linked to electrical remodeling of myometrial
Functional and Molecular Identification of TREK-1 Channel in Myometrium in Relation to Pregnancy and Delivery.
Mammalian ovaries consist of follicles as basic functional units. The total number of ovarian follicles is determined early in life, and the depletion of this pool leads to reproductive aging. During initial recruitment of follicles, unknown in
The Role of Ghrelin in Cisplatin-Induced Infertility
Preterm delivery, an increasingly frequent occurrence in the United States, is associated with significant family burden and an estimated societal cost of at least $26 billion per year. In the U.S., the preterm birth rate is 12-13% as compared
(ARRA) Physiological reactivity to acute stress during pregnancy
Human embryonic stem (ES) cells have great therapeutic potential for various diseases, and generation of these cells has raised many ethical concerns. Therefore, generation of patient-specific (or isogenic) pluripotent stem cells by somatic cel
Generation of Human iPS Cells via Non-integrating Vectors
5R21HD065269-02 (MPI)     Gene Expression and Immune Cell Function in Mothers of Children with Autism. Whole genome expression will be assessed in blood of mothers and compared to autoantibodies in the blood of the mothers. Both of these will b
Gene Expression and Immune Cell Function in mothers of Children with Autism
Bronchopulmonary dysplasia (BPD) is a chronic lung disease that develops in preterm neonates treated with oxygen and mechanical ventilation. BPD causes arrested lung development. The pathogenesis of BPD is still not completely understood. A nov
Role of Microma in Bronchopulmonary Dysplasia
This project will develop a new generation of paramagnetic, functionally oriented probes for the needs of electron paramagnetic resonance (EPR) spectroscopy and imaging, particularly for in vivo applications. EPR- based techniques are far from
(ARRA) NanoSPINS for in vivo EPR-based spectroscopy and imaging
Chronic obstructive Pulmonary Diseases (COPD) are characterized by chronic lung infection and inflammation.  The long term objective of this proposal is to identify means to control inflammation and progression in obstructing airways disease.
Epithelial Cell Bactercidal/Permeability Increasing Protein in Lung Injury
To support the preservation of jobs that are threatened by declines in philanthropic and other support during the current economic downturn, as described in application (A09-904388) and the approved budget.
To support the preservation of jobs that are threatened by declines in philanthropic and other support during the current economic dowturn.
GREATER BALTIMORE YOUTH ORCHESTRA ASSOCIATION, INC.
To support the preservation of jobs that are threatened by declines in philanthropic and other support suring the current economic downturn.
Perelman Theater, Kimmel Center for the Performing Arts
NEW HAVEN SYMPHONY ORCHESTRA, INCORPORATED, THE
LOS ANGELES CHAMBER ORCHESTRA SOCIETY, INC., THE
To support the preservation of jobs that are threatened by declines in philanthropic and other support during the current exonomic downturn.
The objective of this research is to develop methods to monitor and ensure the robustness of a class of cyber-physical systems termed 'physical networks,' such as electric, water, sewage, and gas networks.  The approach is to analyze such netwo
CPS: MEDIUM: A Computing Framework for Distributed Decision Making to Ensure Robustness of Complex Man-Made Network Systems
US 93 from 15.82 miles north of the I15/Garnet interchange to the CL/LN county line.
The interaction of liquid water with plasma ( a higher energy and temperature gaseous environment where some molecules are ionized) occur in a wide range of technological applications and natural phenomena including liquid phase electrical disc
Water Spray in Atmospheric Pressure Electrical Discharge Plasma
The aim of this proposal is to implement a highly focused program at The University of Texas at Dallas that enables seniors enrolled in senior design projects in the Department of Electrical Engineering (EE) to partner with clinical collaborato
Student Design Projects to Aid Hearing Impaired at The University of Texas at Dallas
This NSF award by the Biosensing /CBET program supports work by PI at University of Maryland College Park to develop a label-free biosensor that uses optical waveguides and resonant cavities comprised of nanoporous silicon. Nanoporous silicon i
Nanoporous Silicon Optical Waveguide Cavities for Real-Time Biological Sensing
To support the preservation of jobs that are threatened by declines in the philanthropic and other support during the current economic downturn.
To support the preservation of jobs that are threatened by declines in philanthropic and other support during the current economic downturn, as described in our application (A09-905194) and the approved project budget.
to support the preservation of jobs that are threatened by declines in philanthropic and other support during the current economic downturn, as described in the application (A09-905482)and the approved project budget.
Arts and the American Recoverty & Reinvestment Act of 2009
Through a combination of Gower's expertise in biomimetic engineering and Norton's expertise in electronic materials, a new interdisciplinary research program is proposed that will explore the feasibility of a new biopanning approach for electro
Electroactivated Peptides for Dynamic Functionalization
The goals of this proposal are: 1) demonstrate the ability to sustainably produce H2 from lactose via aqueous-phase reforming (APR), 2) to further develop a synthesis technique for producing bimetallic catalysts with controlled microstructure (
Bimetallic Overlayer Catalysts for Sustainable Fuel Production From Lactose
Photodynamic Therapy causing apoptosis (programmed cell death) rather than necrosis, is a very promising approach for the treatment of numerous cancers. Many PDT-agents can be delivered to cancer cells with high selectivity due to the overexpre
Renilla Transfected Stem Cells as Light Source for In-Situ Photodynamic Therapy of Cancer
Cornell University will establish am Undergraduate Research and Mentoring (URM) program to engage under-represented minority students in intensive mentoring and research experience and prepare them for graduate studies in the biological science
URM : BIOLOGY RESEARCH FELLOWSHIPS FOR UNDERGRADUATES AT CORNELL UNIVERSITY
Efficient infrastructure systems such as highways, bridges, buildings, pipelines, flood control systems and utilities are all necessary for a healthy economy and comfortable standard of living. Concrete and steel are the backbones of physical i
Collaborative Research Thru NSF I/UCRC Full Grant: Center For the Integration of Composites Into Infrastructure (CICI)
Funds are provided to develop methods of electromagnetically monitoring the internal state of sea ice, the thermal evolution of its microstructure, and the transport processes it controls. The PIs will conduct fundamental mathematical studies,
CMG COLLABORATIVE RESEARCH: Mathematics and Electromagnetics for Monitoring Transport Processes in Sea Ice
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  The University of California, Santa Barbara's (UCSB) Division of Mathematical, Life, and Physical Sciences, UCSB's Gevirtz Graduate School of Edu
The Teachers for Tomorrow Noyce Scholarship program provides, over 5 years, a total of forty-nine $15,000 stipends to post-baccalaureate candidates with science and math degrees who commit to teaching in high-need school districts. Recipients a
The goal of the project is to double the number of secondary science teachers graduating from our undergraduate teacher education program. The proposed project will support the recruitment, development and retention of secondary science teacher
Top Notch Teachers with Dual Degrees at the University of Missouri T2D2@MU
Creating STEM Teachers for Arkansas' Future is an educational opportunity attracting Science, Technology, Engineering, and Mathematics (STEM) majors into the teaching profession.
Creating STEM Teachers for Arkansas' Future
The Mathematics Studio Fellowship Program involves a close collaboration between Oregon State University (OSU) and Teachers Development Group (TDG), a non-profit organization for K-12 professional development in mathematics. It builds on a pilo
Mathematics Studio Fellowship Program - A Model for Mentoring New and Master Teachers
Creating Industry-Ready PhD Graduates Creating Industry-Ready PhD Graduates The broad objective of this research is to investigate how engineering doctoral programs can better prepare graduates for careers in industry. Currently, engineering do
This engineering education research award to the University of Illinois at Urbana-Champaign will employ researchers to investigate the learning mechanisms and benefits to engineering education of popular and rapidly expanding international serv
A Participatory Investigation of Learning in International Service Projects
This engineering education research award to Virginia Polytechnic Institute and State University will employ researchers to develop, assess, and disseminate a process model for teaching students how to collaborate in learning environments with
Building New Engineering EducationTheory and Practice for Interdisciplinary Pervasive Computing Design
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5)  This engineering education research award to San Jose State University will integrate fundamental concepts of sustainability into two core lower d
Integrating Sustainability into Lower Division Core Engineering Courses
This engineering education research award to the University of Texas at Arlington will employ researchers to infuse sustainability concepts into the undergraduate curriculum of three major departments, civil, electrical, and industrial engineer
This engineering education research award to the University of Houston in collaboration with Texas Southern University will employ researchers to develop a general framework for remote laboratory experiments with the goal of making access and u
Collaborative Research: Develop Next Generation Unified Framework for Remote Laboratory Experiments
This is a collaborative project involving a consortium of six premier U.S universities and one national laboratory to train graduate students in an area of anticipated manpower need: advanced acceleration techniques. Students will be trained in
This Faculty Development Award supports the effective integration of research, teaching and outreach. The research goals are to characterize the surface corrosion products formed on bronze sculptures using scanning electron microscopy and x-ray
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  The University of Wisconsin-Madison Department of Bacteriology and College of Agricultural and Life Sciences will direct an NSF-funded Internatio
ARRA International Research Experience in Microbiology
The Division of Chemistry supports Eric Spitler of Cornell University as an American Competitiveness in Chemistry Fellow. Dr. Spitler will investigate the potential for covalent organic frameworks (COFs) to efficiently generate and separate ele
PHOTOINDUCED CHARGE SEPARATION IN RETICULAR MATERIALS
The Division of Chemistry supports Sean T. Roberts of the University of Southern California (USC) as an American Competitiveness in Chemistry Fellow. Dr. Roberts will study the dynamics of energy migration in organic photovoltaic materials usin
Exciton Transport and Charge Separation in Organic Solar Cells Visualized with Interface Specific Femtosecond Spectroscopy
The project focuses on the fundamental engineering necessary to develop the direct production of fuel hydrocarbons from cellulose-based waste feedstock. Gliocladium roseum is a recently isolated endophytic fungus, which produces hydrocarbons. T
EFRI-HyBi: Fungal Processes for Bioconversion of Cellulose to Hydrocarbons
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). This project will initiate work on the development of methods for two unprecedented reactions: (1) in situ Grignard formation and use in cross-cou
EAGER: Chemistry of Water-Intolerant Intermediates...in Water
This research is a one-year preliminary investigation into the feasibility and science of low-temperature plasma ignition in free gas bubbles passing through a column of water. Products of such a discharge include ozone, radicals, electrons, hy
EAGER: An investigation of plasma discharge ignition in harmonically driven bubbles in water with applications for the treatment of contaminated water
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).     There is increasing evidence that iron is important in regulating bulk phytoplankton production in large regions of the world oceans and also
Collabroative Research: Microfluidc Assessment of Chemotaxis Towards Different Inorganic and Organically-Complexed Iron species by marine Bacteria & Phytoplankton
Manufacturing industries will emerge from economic crises with a need for workers who can handle the stresses of continuous improvement in Total Quality Management (TQM) and last-second delivery of parts in Just-in-Time Inventory (JIT) systems.
The focus of this project is to perform the basic theoretical and experimental research for a novel method of water desalination using solar energy. A key element of the proposed process is to use seawater as the working fluid and to maintain i
EAGER: Development and Study of Compact Thermal Desalination Systems Driven by Solar Energy
Signal transduction pathways play a key role in many cellular functions as well as intercellular communication. However, elucidating the exact mechanisms involved in signal transduction pathways is non-trivial: crosstalk exists between differen
CDI-Type II: Extracting Population and Stochastic Effects on Signaling Activitity from Transciption Factor Profiles
To support  the preservation of jobs that are threatened by declines in philanthropic and other support during the current economic downturn.
AMERICAN ARCHITECTURAL FOUNDATION INCORPORATED, THE
NEIGHBORHOOD HOUSING SERVICES OF CHICAGO
Arts and the American Rocovery & Reinvestment Act of 2009
To support the preservation of jobs that are threatened by declines in philanthropic and other support during the current economic downturn, as described in application A09-906144 and the approved project budget.
Atrs and the American Recovery & Investment Act of 2009
This research examines practices of software development, co-creation and sharing in collaborative scientific research based on a sample of multiple virtual organizations using the Open Science Grid. Almost every workflow that generates scienti
Socio-Technical Ecosystems for Scientific Software Development
A Comparative Study of Virtual R&D Organizations:  A Sociotechnical Systems Analysis  This study investigates the characteristics of effective virtual organizations across different stages of research and development using a comparative case st
(Voss) A Comparative Study of Virtual R&D Organizations: A Socio-technical Systems Analysis
The University of Illinois at Chicago (UIC) Electronic Visualization Laboratory (EVL) was recently awarded a three-year, $1.9-Million grant from the National Science Foundation (NSF) for “OptIPlanet Cyber-Mashup,” to create persistent visua
STCI OptIPlanet Cyber-Mashup Persistent Visualization and Collaboration Services for Global Cyber Infraestructure
SAN JOSE STATE UNIVERSITY FOUNDATION INC
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). A request is made to fund additional and back-up instrumentation on the R/V Point Sur, a 135 foot, general purpose Regional research vessel. The v
This project is an exploratory research project proposing to evaluate the possibility of a new parallel scripting programming model that can be applied to enable a large, new, and useful class of scientific applications on extreme-scale computi
DESIGN AND EVALUATION OF A PROGRAMMING MODEL FOR PETASCALE PARALLEL SCRIPTING
NORMAN ROCKWELL MUSEUM AT STOCKBRIDGE, INC., THE
Arts and the American Recovery & Reinvestmnet Act of 2009
INTERNATIONAL CENTER OF PHOTOGRAPHY (INC)
The NSF Graduate Research Fellowship Program (GRFP) provides opportunities for graduate education that prepare students for a broad range of careers through its strategic investment in intellectual capital.  So that the nation can build upon th
The NSF Graduate Research Fellowship Program supports graduate student fellowships in NSF disciplines.  Awardees receive three years of full funding (stipend, tuition waiver, health benefits) to be used within a five year period.Students apply
2009-2010 NSF Graduate Research Fellowship
This grant provides fellowship support to individual students who have applied to the NSF Graduate Research Fellowship Program. The funding is awarded directly to students for general support in the Biological, Physical and Social Sciences. Thi
The Super Dual Auroral Radar Network (SuperDARN) is a network of HF radars that provide global-scale and continuous measurements of the high latitude ionosphere and upper atmosphere in both the northern (14 radars) and southern (7 radars) hemis
Collaborative Research: The SuperDARN Upper Atmosphere Facility - Operations, Community Support, and Science from the Polar Cap to Mid-latitudes
The National Science Foundation aims to ensure the vitality of the human resource base of science, technology, engineering, and mathematics in the United States and to reinforce its diversity by offering approximately 1,000 graduate fellowships
this EArlyConcept Grants for Exploratory Research (EAGER) award seeks to use nanoscale electronics technology to develop brain-like computing structures that possess the density and plasticity that allow arrays of synapses to perform sensing, p
Eager: High-Density Electronic Synapse Arrays Using Nanoscale Devices
Atherosclerosis is a systemic disease; however, its manifestations tend to be focal and eccentric. Hemodynamics, specifically, fluid shear stress, is intimately involved in vascular oxidative stress. Oxidative stress induces molecular signaling
Shear Stress and Mechanically Unstable Plaque
Low health literacy is a factor contributing to poorer health status and higher mortality and morbidity among Hispanics. Studies have systematically found low levels of health literacy in this population group. The literature has discussed exte
Health Literacy and ESL: Integrating Community Based Models for the U.S. Mexico region
Cardiovascular disease (CVD) and depression are chronic diseases with complex genetic etiologies. Epidemiological studies have documented the co-occurrence of depression and CVD. However, the potential mechanisms linking depression to CVD remai
GENETIC VARIATIONS IN THE HPA AXIS AND COMORBIDITY OF DEPRESSION AND CARDIOVASCUL
1R21HL092370-01A2 MUSCULARIZATION OF PULMONARY ARTERIES INDUCED BY AN ADAPTIVE IMMUNE RESPONSE. Muscularization of pulmonary arteries induced by an adaptive immune response Abstract Pulmonary arterial hypertension (PAH) is a devastating conditi
Muscularization of pulmonary arteries induced by an adaptive immune response
According to the National Center for Environmental Health one in four Americans suffers from asthma or allergies with the direct costs of treating asthma totaling more than $10 billion every year.  In addition, Asthma rates in children under th
EPIGENETIC CONTROL OF ASTHMATIC INFLAMMATION BY ATF3
The purpose of this funded project is to optimally design synthetic hydrogel scaffolds of poly(ethylene glycol) diacrylate (PEGDA) that promote rapid vascularization (angiogenesis) which is essential for the clinical success of implantable tiss
PEG Hydrogel Enabling Technologies for Guiding Endothelial Cell Function
Cardiovascular disease is the leading cause of death, and one of the primary causes of disability worldwide. Atherosclerosis is the primary contributor to cardiovascular disease. About one-half of the deaths that can be attributed to cardiovasc
(ARRA) PTENuating restenosis: An innovative PTEN promoter for cardioprotection
Significant gender differences in the prevalence of cardiovascular disease have been demonstrated. The risk of developing cardiovascular disease is considerably lower in pre-menopausal females than in age-matched males, whereas after menopause,
Gender Differences in Caloric Restriction Cardioprotection
The major barrier to use of autologous EPCs in regenerative vascular medicine is the low number and limited trans-differentiation potential. It is necessary to develop an efficient method to increase the number and/or potency of autologous EPCs
Epigenetic modification of endothelial progenitor cells into multipotent cells
There is considerable public and professional concern that the two most widely prescribed stimulants for youth with attention-deficit/hyperactivity disorder (ADHD), mixed salts of amphetamine (MAS) and methylphenidate (MPH), may increase the ri
DESCRIPTION (provided by applicant): Mood disorders represent a class of devastating illnesses that have profound impact upon individuals, families, communities, employers, and health care systems. While many medications and therapies exist for
microRNA Expression Patterns in Human Psychiatric CNS Samples
Bipolar disorder (BPD) is among the 10 leading causes of disability in the developed world. The etiology of the disease is unknown and treatment options are based on either serendipitous discoveries of mood stabilizing effects of certain substa
A Model System for Abnormalities in Electron Transport Genes in Bipolar Disorder
Depression is a leading cause of disability worldwide. Yet, despite the discovery of clinically-effective antidepressants over fifty years ago, the biological mechanisms of the illness remain mostly uncharacterized. As a result, very few new dr
Modeling Core Behavioral, Neuroendocrine and Molecular Features of Depression
This proposal aims to develop an 18F-labeled agonist PET probe for in vivo quantification of the G-protein coupled high affinity serotonin 1A (5-HT1A) receptors in baboon. We have two major motivations for developing an 18F labeled 5-HT1A recep
Development of 18F-Labeled Agonist PET Probes for Quantifying 5-HT1A Receptors
GABA modulation and negative affect in psychosis Schizophrenia frequently presents with clinically significant negative affect. In addition to co-morbid depression and anxiety disorders (up to 60 O/O), patients show high levels of trait negativ
GABA MODULATION AND NEGATIVE AFFECT IN PSYCHOSIS
Profound impairment in social interaction is a hallmark of autism spectrum disorders (ASD). Although improvement in social functioning is widely considered to be a crucial target for intervention, social skills treatments for school-age childre
NEURAL AND BEHAVIORAL OUTCOMES OF SOCIAL SKILLS GROUPS IN CHILDREN WITH ASD
Autism is a lifetime disorder, but surprisingly little is known about the effects it has on the individual's abilities, needs, and experiences as he or she reaches and continues through adulthood. The first descriptions of autism spectrum disor
AUTISM IN THE SECOND HALF OF THE LIFESPAN: BEHAVIOR, DAILY LIVING, SERVICE NEEDS
The risks and potential harms associated with participation in survey research are virtually unknown.  Previous work has documented emotional distress in subjects with existing emotional vulnerabilities, although the severity and duration of th
Predicting occurrence and minimizing negative impacts of survey research
DESCRIPTION (provided by applicant): It is now accepted that Multiple Sclerosis (MS) is not just an inflammatory demyelinating but also a degenerative disease of the central nervous system (CNS) with early axonal transection, followed by neuron
BDNF-engineered stem cell mediated neuroprotection in EAE
Iron accumulates in brain regions that undergo degeneration in several neurodegenerative diseases such as Alzheimer disease (AD) and Parkinson disease (PD) (1-3). However, the precise role of iron in the neurodegenerative process is unclear. Th
Malignant glioma is characterized by early local invasion, microsatellite infiltration of healthy CNS tissue and dispersion of tumor cells in distant parenchyma. These characteristics significantly hamper the success of surgical or radiation tr
Enterovirus Vectors with Respiratory Tropism for Cancer Immunotherapy
An Interactive Web-Based Game for Collaborative Labeling of Medical Images. The proposed research investigates extension of established practices for volumetric labeling and web-based collaboration to create an innovative infrastructure for lab
AN INTERACTIVE WEB-BASED GAME FOR COLLABORATIVE LABELING OF MEDICAL IMAGES
The project is aimed at developing new image analysis techniques to characterize brain atrophy in the R6/2 mouse line, a mouse model of Huntington&apos;s disease (HD). Atrophy of specific brain structures is known to be an important marker of H
CHARACTERIZATION OF BRAIN ATROPHY IN HUNTINGTON?S DISEASE MOUSE MODEL
The work is complete and the remaining balance of the award will be returned to NIH.    Dendrites and axons extend long distances from the neuronal cell body and so can be damaged independently from it. It is known that axons possess their own
NEURONAL EVENTS AND MOLECULAR PATHWAYS IN ACTIVE DENDRITE DEGENERATION
Malignant glioma is the most aggressive and deadly brain tumor in adults. Despite the improvement of imaging technology and surgical removal of the tumors significantly reduces the mortality of malignant glioma, how to enhance the sensitivity t
ROLE OF TRIP6 IN MALIGNANT GLIOMA PROGRESSION
Live-cell imaging has become a valuable analytical tool in most biomedical laboratories, as well as a routine methodology used in wide ranging fields of neurobiology, developmental biology, pharmacology, etc. The phase contrast microscope has b
Fourier phase contrast microscopy techinque for biomedical research
OFFICE OF RESEARCH AND SPONSORED PROGRAMS
Title: Analysis of Ubiquitinated Proteome  Like phosphorylation, protein ubiquitination is a reversible process to regulate essentially all cellular events. Misregulation of ubiquitination plays an important role in the pathogenesis of a variet
The goal of this project is to develop a sonar system that can be used as a mobility aid by the visually impaired. The system will consist of an ultrasonic acoustic source using a waveform that is designed to optimize target discrimination and
An Acoustic Mobility Aid for the Visually Impaired
item of SFQP. GOAL 3: Demonstrate safety of proposed program for clinic and home use. Measurable Outcome - No falls or significant safety issues.
Computer-based Video Game Therapy for Gait and Balance in Cerebral Palsy
Project Title:  Calcium Phosphate Bone Cement Nanocomposites Project Description: Calcium phosphate cements (CPCs) are used in orthopedic surgery as bone filler and have been proved with very good biocompatibility. However, the inadequate mecha
Calcium Phosphate Bone Cement Nanocomposites
Surgical and Medical Instrument Manufacturing
NeoStem will conduct research on stem cells and explore their enormous promise to produce breakthrough therapies and cures.  The study will investigate the effect of a marrow population of mesenchymal cells (MSCs)that are very small and have em
Repair of Boney Defects by Human Stem Cells
Since early development of polymethyl methacrylate bone cement (PMMA-BC), there have been many efforts to develop alternative compositions to circumvent some of its clinical shortcomings, which include (1) monomer cytotoxicity; (3) inability t
platform, based on Encoded Sortable Particle (ESP) technology to make it cost and performance compatible with high multiplex assays. ESPs are optically-encoded microfabricated particles that can be manipulated using magnetic force. We will ada
High Multiplexing Liquid Array Assay Platform
This is a phase I SBIR proposal that aims to demonstrate a near-patient platform for screening neonates with very high levels of bilirubin (hyperbilirubinemia). The proposed devise would be greatly useful in rapid identification and enable earl
This research project investigates the mechanisms used by the opportunistic fungal pathogen, Candida albicans to produce disease. The long term goal of this research is to understand how C. albicans cells cause infection. Environmental sensing
CONTACT SENSING AND C. ALBICANS-HOST INTERACTION
Hepatitis C virus (HCV) infection persists for years in most patients and leads to chronic liver disease despite robust immune responses. Although there are no clearly established in vitro correlates of protective immunity, multiple lines of ev
Multiple Sclerosis is an autoimmune disease resulting from complex interactions between genetic background of the individual and his/her environment. Our combined data suggests that genetic deficiency in a pathway that controls the addition of
Multiple Sclerosis and Genetic Defects in N-Glycosylation
The pituitary transcription factor, Pit-1, is responsible for both normal development of the anterior pituitary gland and cell specific expression of three of the pituitary peptide hormones. A clear understanding of the regulation of transcript
Signaling Mechanisms Regulating Pituitary Gene Expression
ClipR-59 is a member of Clip-170 protein family, characterized by presence of three ankyrin repeats and two cytoskeleton-associated protein-Glycine rich (CAP-Gly) domains (also referred as microtubule binding domain (MTB). However unlike other
ClipR-59: a novel regulator of Akt Signaling
Sickle cell disease (SCD) is a genetic disease that causes severe, lifelong pain, debilitating organ toxicity and early death. Many of the complications can be ameliorated by blood transfusions, which in turn cause significant iron overload.  A
Iron-Mediated Vascular Disease in Sickle Cell Disease
This application is submitted in response to the NIH Announcement (RFA-OD-09-003) and the proposal addresses the broad Challenge Area (08): Genomics, and the specific Challenge Topic, 08-AA-104: Regional Central Nervous System (CNS) Gene Expres
Gene Expression Profiling in a Mouse Model of Ethanol Dependence and Drinking
Although some degree of gradual cognitive decline is nearly universal and a normal part of the aging process, previous research by our group has shown that age-related cognitive decline is amenable to intervention. Building on speed of processi
RCT of Two Speed of Processing Modes to Prevent Cognitive Decline in Older Adults
This application addresses broad Challenge Area (08) Genomics and specific Challenge Topic, 08- AG-101: Genetic factors affecting rates of change in disease risk factors with age. Alzheimer's disease (AD) is the most critical unmet need in neur
GENETIC FACTORS THAT IMPACT THE RISK OF ALZHEIMER'S DISEASE
The investigators will leverage their significant experience with CMS claims and their active participation in three nationwide research networks to compile a very large permanent (yet continually updatable) national data resource for the purpo
Data Infrastructure for Post-Marketing Comparative Effectiveness Studies
We propose a response to Challenge 06-AG-104 that incorporates development of three novel tools and technologies that can alter or interrogate human mitochondrial function in vivo.  We will then apply these tools to the study of aging heart and
Interrogating and manipulating mitochondrial ROS, energetics and proteomics
Amyloid is the dangerous brain plaque and tau protein tangles with in the brain cells tend to prevent neurons from communicating each other leading to loss of memory. Positron emission tomography (PET scan) can create image of the harmful beta
Novel PET Imaging Agents for Early Diagnosis of Plaque Deposition in Alzheimer's Disease - ARRA Stimulus Challenge Grant
The proposed research takes advantage of the strengths of one of the oldest and most widely used neurological assessments in clinical practice, the Rey Auditory Verbal Learning Test (RAVLT).  We will apply cutting-edge mathematical modeling too
LOW-BURDEN TOOLS FOR IMPROVING PREDICTION AND DIAGNOSIS OF COGNITIVE IMPAIRMENT
This application addresses broad Challenge Area (03) Biomarker Discovery and Validation and specific Challenge Topic, 03-AI-101: Identification, characterization and evaluation of novel pathogen or host targets that may lead to the development
Develop Antibiotics that Inhibit Bacterial Virulence proteins
This application addresses broad Challenge Area (04) Clinical Research and specific Challenge Topic 04-AI- 102: The human immune response to infection and immunization - Profiling via modern immunological methods and systems biology. The abilit
IMMUNE PROFILING OF MULTI-PARAMETER FLOW CYTOMETRY USING COMPUTATIONAL STATISTICS
This application addresses broad Challenge Area (04) Clinical Research and specific Challenge Topic, 04-AR-101: Autoimmunity For Diseases Of The Skin, Joints, Muscle And Other Tissues-Develop reagents and analytic methods to identify, character
Analytical microtools for discovering autoreactive lymphocytes
This research project seeks to improve understanding of the connection of bone marrow fat (BMF) with bone density, geometry and turnover by recruiting 150 men who are currently participating in the Osteoporotic Fractures in Men (MrOS) study at
Epidemiologic Study of Bone Marrow Fat and Osteoporosis
This proposal will provide information essential to informing treatment decisions for patients with psoriasis and future, longitudinal comparative effectiveness studies. Ultimately, this line of research will lead to more rationale treatment de
Comparative Effectiveness of Biologics for Psoriasis
Our goal is to determine the effect of diet on skeletal acquisition, specifically whether perinatal diet initiates developmental programming of the skeleton that alters postnatal acquisition of bone mass, microarchitecture and strength. We have
Effect of Perinatal Diet on Developmental Programming of the Skeleton
This application addresses broad Challenge Area (15) 'Translational Science' and specific Challenge Topic '15-AR-104 Bone and the Nervous System'. Bone adaptation requires osteocytes to detect mechanical signals in situ and integrate the signal
Implicit Learning in Osteocyte Network under Mechanical Loading
This application addresses broad Challenge Area (06) Enabling Technologies and specific Challenge Topic 06-AT-101: In this project, we propose two project areas based on the use of Magnetic Resonance Imaging modalities at both the cerebral (bra
IMAGING CEREBRAL AND SUB-CEREBRAL CORRELATES OF MEDITATIVE STATES
This application addresses Broad Challenge Area (5), Comparative Effectiveness Research, and specifically Comparative Effectiveness Research on Cancer Screening, 05-CA-102. Significance: With our health care system in financial crisis, and colo
Comparative Effectiveness of FIT vs. Colonoscopy for Colon Cancer Screening
The ability of malignant glioma cells to invade normal brain severely limits all current therapies for this devastating disease. Blocking this process could therefore convert gliomas from an invasive, whole brain disease to a local disease—on
MICROSYSTEMS AND MODELING APPROACH TO GLIOMA MIGRATION AND METASTASIS
This Challenge Grant entitled “Oncogenic Human Papillomavirus Network” will enable technologies that provide new tools and insights for basic research to create new avenues of research into the specific mechanisms that can lead to a better
Oncogenic Human Papillomavirus Protein Network
This research proposes a non-invasive blood test for prostate cancer which avoids the pitfalls that have plagued the Prostate Specific Antigen test (high false negatives and positives), a consequence of comparing a patient's test results to an
Detection of Prostate Cancer Genomic Signatures in Blood
Tumor angiogenesis represents a critical event of cancer that involves the recruitment of bone marrow derived endothelial progenitor cells; however, the exact mechanisms and effects by which microenvironmental conditions regulate these processe
MICROFLUIDIC TUMOR MODELS TO ANALYZE THE ROLE OF PHYSICOCHEMICAL CUES IN THE ANGIOGENIC SWITCH
Specific targeting of oncogenic signaling pathways with kinase inhibitors has vastly improved clinical outcomes for patients with a variety of cancer diagnoses, most notably patients with chronic myeloid leukemia. To expand this targeted-therap
Accelerating target identification and validation in leukemia: Integrating siRNA-
This application for an NIH RC1 Challenge Grant in Health and Science Research addresses the following Challenge Areas: (04) Clinical Research and (15) Translation Science. The specific Challenge Topics it addresses are 04-DK-104, Improve the d
Hepatitus B Virus PreS2 Mutant as Risk Factor for Hepatocellular
Malignant tumors evade the immune attack by exploiting the natural regulatory mechanisms of immune tolerance. CD4+CD25+ Tregs that play a critical role in immune tolerance accumulate in the draining lymph nodes and tumor mass of patients with m
ROLE OF TIEG1 IN FOXP3+TREG DEVELOPMENT AND TUMOR PROGRESSION
Vincristine is active against a wide variety of malignancies and has been shown to substantially improve outcomes. Although vincristine is among the most commonly used anticancer agents, little is known about optimal therapeutic dosing and it i
Developing A Prediction Model for Vincristine-induced Peripheral Neuropathy
The purpose of this research is to design and synthesize novel Beta-lactam containing compounds to use as chemical probes to better understand the biology of glutamate transporter subtype 1(GLT-1) upon activation by the Beta -lactam antibiotic
Beta-lactum chemical probes for GLT-1 transporter-related pathologies
The overall goal of the proposed study is to identify neurophysiological and behavioral markers of sensitivity to smoking cessation treatment. Although smoking widely recognized as the major preventable cause of death and substantial proportion
NEUROCOGNITIVE PREDICTORS OF SMOKING CESSATION
Among US adults, 12.8% report nicotine dependence, and nicotine dependence is highly associated with a variety of DSM-IV Axis I and II disorders.  Pathological gambling (PG), a serious public health problem with detrimental effects on individua
N-Acetyl Cysteine for Nicotine Dependent Pathological Ga
This research proposal, entitled 'A Novel Epigenetic Gene Silencing Technology', addresses the broad Challenge Area: (06) Enabling Technologies, and specific Challenge Topic, 01-OD-107: Functional Modulation of Epigenomic Modifications. The abi
A NOVEL EPIGENETIC GENE SILENCING TECHNOLOGY
Genetic/Epigenetic Markers, Social Contexts, Lifecourse & Risky Health Behaviors    This project addresses broad challenge area (01) Behavior, Behavioral Change, and Prevention and two highly related specific Challenge Topics: (A) 01-OD(OBSSR)-
Genetic/Epigenetic Markers, Social Contexts, Lifecourse & Risky Health Behaviors
In response to Challenge Area 04: Clinical Research and specific Challenge Topic 04-DC-101: Prevention of Otitis Media, we propose a clinical trial of a preparation of viscous xylitol with a mucosal adherence agent for the prevention of acute o
Xylitol syrup for the prevention of acute otitis media in otitis-prone children
Although small-scale studies have evaluated oral disease in the developmentally disabled, the oral health status, treatment needs and helpful interventions for adults with developmental disabilities (DD) are largely unknown. The inability of ma
ORAL HEALTH STATUS AND ITS CORRELATES IN ADULTS WITH DEVELOPMENTAL DISABILITIES
Tufts Dental Facilities, Fernald Development Ctr
OLD DOMINION UNIVERSITY RESEARCH FOUNDATION
The project seeks to tailor existing Screening, Brief Intervention, Referral and Treatment (SBIRT) protocols for alcohol abuse to be used in dental practice settings.  SBIRT protocols have demonstrated effectiveness in reducing alcohol use and
Adoption Fidelity and Effectiveness of Alcohol SBIRT in Dental Practice
This application addresses broad Challenge Area (15) Translational Science and specific Challenge Topic, 15-DE-101 Molecular Profiling and Developing Mouse Models for Salivary Gland Tumor Research. The proposed work will expand an ongoing succe
Molecular characterization of a human salivary gland tumor xenograft bank
This application addresses broad Challenge Area (13) Smart Biomaterials - Theranostics and specific Challenge Topic, 13-DE-101* Novel Self-Healing Smart Dental and Bio-Restorative Materials. Effective repair and replacement of skeletal tissue b
Self-Healing Composites via Novel Biomolecular Design and Processing
The Use of Erythropoietin to Reprogram Oral and Craniofacial Stem Cells. This project directly addresses Challenge Area (14)-Stem Cells, specifically 14-DE-101* Reprogramming of Cells from Oral and Craniofacial Tissues in which we developed a n
THE USE OF ERYTHROPOIETIN TO REPROGRAM ORAL AND CRANIOFACIAL STEM CELLS
foods will improve the general understanding of how simple lifestyle changes can yield profound benefit for managing and preventing insulin sensitivity, thereby increasing the likelihood that members of the general population will commit to th
Dietary Nitrate Activation of PPARgamma Improves Insulin Sensitivity
with hepatocytes derived from patients with metabolic disease. In addition, iPSC technology will be utilized to reprogram the liver cells from metabolic disease patients and following hepatic differentiation, additional mice will be humanized
Mice Humanized with Hepatocytes and iPS Cells from Patients with Metabolic Diseases
This application addresses Broad Challenge Area (04) Clinical Research and specific Challenge Topic, 04-DK-106: Preservation/Recovery of endogenous insulin secretion. Diabetes is a serious and common metabolic disorder that afflicts 18 million
A PROOF-OF-CONCEPT CLINICAL TRIAL OF XENIN-25 IN THE TREATMENT OF TYPE 2 DIABETES
The hypothalamic-pituitary-adrenal (HPA) axis and its byproduct, cortisol, have been hypothesized to be the mediators that links chronic stress to adverse health outcomes, including increased obesity risk. This mediation is hypothesized to occu
CORTISOL AND EATING BEHAVIOR IN LOW-INCOME PRESCHOOL-AGED CHILDREN
US 95 approximately 1.5 miles north of the Laughlin Highway(SR 163)
This grant will build a geolinguistic infrastructure for more work on language mapping, language relationships and language change in the Arctic, illuminating language shift, language death, and language contact.  The project will enhance exis
ICE - Integrating Cartographic Elements: Creating Resources Emphasizing Arctic Materials
COUNCIL OF LITERARY MAGAZINES AND PRESSES
Arts and American Recovery and Reinvestment Act of 2009
To support the preservation of jobs that are threatened by declines in philanthropic and other support during the current economic downturn, as described in our application (A09-904894) and the approved project budget.
PARKS AND RECREATION, WASHINGTON STATE COMMISSION OF
NATIONAL COUNCIL FOR THE TRADITIONAL ARTS, INC.
The National Center for Atmospheric Research (NCAR) has for several decades been the principal provider of high-performance computing (HPC), data storage resources, software engineering and visualization tools for the atmospheric and related sc
NCAR-Wyoming Supercomputing Center (NWSC) Project Office (NPO)
Fluid flows over rough surfaces constitute an important and challenging class of problems in fluid dynamics with both industrial applications and natural examples. Many materials and products have a surface texture by design or one that evolves
Thin-film flows over topographically patterned surfaces: Free-surface characteristics, atomization, and cleaning
HISTORY, ARTS & LIBRARIES, MICHIGAN DEPARTMENT OF
To support arts projects and activities that preserve jobs in the nonprofit arts sector threatened by declines in philanthropic and other support during the current economic downturn.
STATE TREASURER, MASSACHUSETTS DEPARTMENT OF
Arts and The American Recovery and Reinvestment Act of 2009
To support the preservation of jobs that are threatened by declines in philanthropic and othersupport during the current economic downturn.
ECONOMIC & COMMUNITY DEVELOPMENT, OREGON DEPT OF
To preserve jobs in the nonprofit arts sector that are in jeopardy due to declines in philanthropic and other financial support during the current economic downturn.
WEST VIRGINIA DIVISION OF CULTURE & HISTORY
CULTURAL COUNCIL OF GREATER JACKSONVILLE
ARRA Congregate Nutrition Services- 2009 T3C1_ARRA
ARRA provided funding for home delivered meal services.  Established in 1972 under the Older American Act, the program provides meals for older americans in their homes.
ARRA provided funding for congregate nutrition services.  Established in 1972 under the Older Americans Act, the program provides meals to older Americans in congregate facilities such as senior centers, senior housing units, etc.
The Congregate Nutrition Services program provides funding to local providers to deliver healthy meals to seniors in settings such as senior centers, adult day centers, and faith-based settings, helping seniors maintain their health and avoid h
Provided nutrition services for frail elderly in congregate meal settings.  Funding was distributed through the Area Agencies on Aging to local and county/tribal aging offices.   These offices contracted for a variety of services including meal
This project will implement wood placement in streams by a helicopter in three stream systems, Knowles, Upper Buck, and Prindle.  This project was developed in cooperation with numerous partners to implement placing wood in high priority stream
Siuslaw Watershed Council In-Stream Helicopter Wood Placement
Water Resources, Wetlands Conservation & Management
The Houlton Band of Maliseet Tribal Housing Authority is building a new 10,000 sq ft eight unit apartment building.  The project is a new free standing apartment building located in Houlton, Maine off the Foxcroft Road on the Houlton Band of Ma
To build a 15 new construction units and a 4,000 sf community center.
New housing construction utilizing the Force Account method of construction
Native American Housing Block Grant Program.  Grant No. 09CH3506730
The Cheyenne-Arapaho Housing Authority was awarded under the recovery act $3,000,000.00 competitive Indian Housing Block Grant.  The activities will be to purchase 4-6 homes for low-income elders, and rehabilitation of 71 mutual help homes.  Ca
Native American Housing Block Grant- COMPETITIVE - new construction of rental housing with intended outcomes of: create new affordable rental units, provide accessibility for disables/elderly persons, and improve energy effency on these new uni
Recovery Act - Competitive, Construction of rental housing
The purpose of the 72-unit Kwina Village Apartments project is two-fold:  first, to provide decent and affordable rental housing for Low-Income tribal families, and second, to create jobs for tribal members and others in the construction trades
Native American Housing Block Grants (Competitive)Recovery Act Funded
REHAB 18: 1937 LOW RENT UNITS. A REHAB OF UNITS WILL BE COMPLETED BOTH INSIDE/OUTSIDE INCLUDING ADDING A GARAGE.
ARRA Cost-of-Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act. In efforts to: 1.) Improve compensation of staff in order to attract and retain qualified staff to
This agreement will help maintain the real-time MM5 and WRF model weather forecasts over the Northwest and will provide the Forest Service with real-time access to the model grids. It will also include providing access to archived model grids.
The Jacob's Brook Bridge project award goes to pay to have a student-designed foot-bridge built over Jacob's Brook on the Appalachian National Scenic trail in the saddle between Smarts Mountain and Mount Cube in Orford, NH at the top of Quintto
The purpose of this Challenge Cost Share Agreement is to establish a framework for working together on the White Mountain National Forest trail maintenance needs and to complete reconstruction objectives on the Wonalancet Out Door Club trails a
Construction of six single family houses for low income Indian families.
Hire staff, construct two new homes, rehabilitate twelve homes, and construct two roads.
To construct 2 green and sustainable housing units at Pinoleville Heights sub-division. The infrastructure is all in place and units will be constructed as soon as plans are finalized.
To construct 2 green and sustainable housing units.
The overall purpose of the project is to construct a 10 unit assisted living facility on the Fond du Lac Reservation.  The funds will be used to build a 10 unit facility to provide both short and long term care for people in need of medical att
Fond du Lac Reservation Assisted Living Project
Construction of Slocum Ridge III - Multifamily Housing Project will best fit the Tribes' urgent need for housing for those on the waiting list for two bedroom units, and assist others that are currently being impacted by the recession by provid
Slocum Ridge III -Multifamily Housing Project
Native American Housing Block Grant - New Housing Construction
Project consists of two subprograms:  Lincoln County Fuels Mitigation ($520,000) and Lincoln County Urban Forest Enhancement ($288,000).  The Lincoln County Fuels Mitigation funding ($520,000) will provide wildfire fuels hazard reduction treatm
Lincoln County Fuels & Ecosystem Restoration
also to protect the pueblo village and its watersheds, the wilderness areas and its wildlife habitats and the adjacent outlying communities from wildfire. The project conforms to all of these objectives.  Additionally, reduction of over-stocke
Forest Preventative Fuels Treatment on Taos Pueblo Lands
OREGON DEPARTMENT OF COMMUNITY COLLEGE & WORKFORCE DEVELOPMENT
The Oregon Youth Employment Initiative (OYEI) award has an overall purpose to: preserve and create jobs that promote economic recovery, assist those most impacted by the recession and to invest in environmental protection.  The funds will provi
The purpose of the projects being funded are to address forest health issues related to overstocking by pre-commercial thinning and fuels mitigation. The main objectives are to reduce stem density on 11,070 acres of commercial forest stands to
These projects will provide hazardous fuels reduction treatments on a total of 3,093 acres in Jackson, Josephine, Crook, Deschutes, Jefferson, Linn and Lane counties.  A portion of this award will provide private landowners with financial incen
The Florida Department of Agriculture and Consumer Services, Division of Forestry will improve the condition of longleaf pine forests on state and privately owned forest lands.  Activities may include longleaf pine establishment on lands not cu
Florida Regional Longleaf Pine Restoration Initiative and Fuel Reduction
Hazardous fuels mitigation projects within the Fairbanks North Star Borough & rural Alaska.  Projects within the the Fairbanks North Star Borough include Washingtion Creek, South Fork Chena & Salcha.  The projects will provide fuel breaks betwe
Hazardous Fuels Mitigation in Interior Alaska
Dept of Natural Resources Financial Services
Promote regeneration and repair in the digestive system, liver, pancreas, kidneys, Hematologic, and urological system. The stress of major surgical procedures, irradiation, chemotherapy, nutritional deprivation, and systemic inflammation all le
Targeting Myofibroblast for Intestinal Epithelial Regeneration
Extracorporeal Support for Emergent (Uncontrolled) Donation Following Cardiac Death Introduction: The limited availability of donor organs for transplantation has led to an increased interest in the use of donation following cardiac death (DCD)
EXTRACORPOREAL SUPPORT FOR EMERGENT (UNCONTROLLED) DONATION FOLLOWING CARDIAC DEA
Dysregulation of the immune system, which induces an aberrant activation of leukocytes, plays a critical role in the pathogenesis of a wide range of autoimmune and immunological disorders including such inflammatory bowel diseases (IBD) as ulce
Targeted siRNA delivery to aberrantly activated leukocytes for treating colitis
In the last several years, there has been a remarkable transformation in the field of cancer therapeutics, with a shift from traditional 'cytotoxic' agents to targeted therapies. There has also been a rapid increase in the number of potential c
ARRA Volumetric Perfusion MRI of Liver Tumors to Detect Early Response to Chemotherapy
Multiplexed diagnostic assays that are rapid, easy to use, and very low cost are needed for use at the point of care (POC), especially in low-resource settings. Microfluidic systems can bring laboratory-quality multiplexed assays to POC applica
A SENSITIVE MULTIPLEXED DIAGNOSTIC PLATFORM USING DISPOSABLE 2D PAPER NETWORKS
This study examines 1800 patients treated at more than 20 centers with expertise in robotic and standard prostate surgery; the patients have been evaluated for quality of life before and after surgery, and for complications, costs, and cancer c
EFFECTIVENESS OF ROBOTIC COMPARED TO STANDARD PROSTATECTOMY FOR PROSTATE CANCER
This application addresses broad Challenge Area (15) Translational Science and specific Challenge Topic, 15- ES-101*: Effects of Environmental Exposures on Phenotypic Outcomes Using Non-Human Models. Farmers as a group have the highest occupati
Effects of Pesticides on Prostate Cancer Progression in PTEN Mutant Mice
This application addresses broad Challenge Area (15): Translational Science and specific Challenge Topic, 15- ES-101*: Effects of Environmental Exposures on Phenotypic Outcomes Using Non-human Models. The overall goal of this research proposal
Transgenerational epigenetic effects of PCBs on neuroendocrine systems
This application addresses broad Challenge Area (08) Genomics and specific Challenge Topic 08-ES-104, Identification of Alterations in Epigenetic Marks Related to Environmental Exposures. Environmental exposure to foreign chemicals with estroge
EPIGENETIC MARKS OF XENOESTROGEN EXPOSURE
Aims of the proposal:  1) Contribute to the development and competency of pre-service STEM teachers through integration of Environmental Health-based Biotechnology lessons into an existing methods course. 2) Intergrate Environmental health scie
INTERGRATING ENVIRONMENTAL HEALTH-BASED BIOTECHNOLOGY INTO STEM TEACHING FOR HIGH SCHOOL TEACHERS
This application addresses broad Challenge Area (03) Biomarker Discovery and Validation and specific challenge topic, 03-ES-101 Validation of new exposure assessment methodologies Suboptimal dietary macronutrient choices are arguably the major
Validated Biomarkers for Primary Macronutrient Balance
This  application  addresses  the NIH broad  Challenge  Area  (11)  Smart  Biomaterials,  and  the specific Challenge Topic, 11-EB-103, Modular Platforms for Regeneration and Development.     Working under this award we will create for the firs
RETINAL SCAFFOLDS: SYNAPTIC AND STEM CELL INTEGRATION
This proposal outlines a set of experiments under broad challenge area (05) Comparative Effectiveness Research which will address the highest-priority challenge 05-EY-102 Treatment of Pediatric Eye Diseases and Disorders. Specifically, it will
Downregulation of Rod Metabolism in Retinopathy of Prematurity
This application addresses broad Challenge Area (15) Translational Science and specific Challenge Topic, 15-EY-101: Protein misfolding in degenerative diseases of the eye. Identifying therapeutic pharmacological agents/drugs that prevent the mi
Development of Small Heat Shock Proteins as Therapeutic Agents in the Eye
Challenge Area: 06 Enabling Technologies. Specific Challenge Topic: 06-GM-101 Structural Analysis of Macromolecular Complexes. A major challenge in chromatin biology and molecular cytology is how to study the macromolecular structures of specif
Reading the histone code:nanoscale morphology of Epigneomic Histone Modifications
This application addresses broad Challenge Area (14) Stem Cells and specific Challenge Topic, 14-AG-105 Exploratory studies of induced pluripotent stem (iPS) cells from healthy individuals and patients with mental/nervous system disorders. Chro
Nuclear Organization in Stem and Differentiated Ce
This application addresses the broad Challenge Area: 08: Genomics, and the specific Challenge Grant Topic: 08-AG-105**: Approaches to study the interactions among individual behaviors, social and physical environments, and genetic/epigenetic pr
Exploring Persistent Epigenetic Changes after Prenatal Famine Exposure in Humans
This grant proposes to significantly advance the current technology for generation of mouse models of human genetic disease. This addresses broad Challenge Area (15) Translational Science, and Specific Challenge Topic 15-OD(ORDR)-101: Pilot pro
RAPID AND INEXPENSIVE SCREENING OF DISEASE CANDIDAT GENES IN MICE
The purpose of the proposed studies is to evaluate a novel combination treatment in experimental traumatic brain injury (TBI). Traditional treatment strategies for TBI aim to prevent delayed neuronal cell death by inhibiting one proposed cell d
Combination drug treatment to inhibit multiple cell death pathways after TBI
A two year project is proposed to expand, to exploit, to extend, and to apply on a demonstration basis a completely novel approach to high throughput cis-regulatory analysis. We have very recently developed the initial component of this new te
This project brings together top experts on nanomedicine, biomedical engineering, law, policy, and bioethics to produce the first systematic and comprehensive recommendations on how to protect human participants in research on nanodiagnostics a
NANODIAGNOSTICS AND NANOTHERAPEUTICS: BUILDING RESEARCH ETHICS AND OVERSIGHT
One of the greatest challenges in biochemistry is to study dozens to hundreds of molecules simultaneously using single cells or in single cell types obtained from complex, living tissue. Here, we propose a new technology, termed ?microlysis tec
Microlysis Technology: Enabling Cell Type-Specific Proteomics in Living Tissue
This challenge grant will help to stimulate the economy as it proposes to hire two new full-time research assistants. These individuals will work on a project aimed at assesing the social, behavioral, and ethical implications of direct availabi
Assessing Attitudes and Experiences of Early Adopters of Personalized Genomics
This application addresses broad Challenge Areas (15): Translational Science and Specific Challenge Topic 15-HL-102: Develop therapeutic strategies for heart, lung, and blood diseases based on microRNA technology. One type of RNA editing involv
Control of Cardiogenesis by microRNA Editing
We request funding to support one additional cycle of observational follow-up of Women's Health Study (WHS) participants, to ascertain and validate cardiovascular disease (CVD) and cancer endpoints among cohort subjects, in order to retain jobs
The Women's Health Study: Addition of New Data to Maximize its Research Impact
The main objective of this project is to develop a protein based therapy to enhance the endothelial barrier properties. Although acute lung injury (ALI) is a major cause of morbidity and mortality, no curative therapies are available. The main
This application addresses broad Challenge Area (15) Translational Science and specific Challenge Topic, 15- HL-101: Develop improved biocompatible surfaces for implantable blood-contacting medical devices. More than five million Americans, and
Autologous EPC lining to improve biocompatibility of circulatory assist devices
The overarching goal of this proposal is to characterize the mechanisms through which SDB may lead to alterations in glucose metabolism and determine the putative role of ET-1. To accomplish our goals, we will employ a combination of unique obs
MECHANISMS LINKING SLEEP-DISORDERED BREATHING AND CARDIOVASCULAR DISEASE
With this award our goal is to use biomarkers of platelet factor 4 (PF4), platelet activation and immune response, along with clinical factors to identify patients at risk of heparin/PF4 antibody formation.  Patients who undergo surgery requiri
Novel Biomarkers Predictive of Heparin-Inducted Thrombocytopenia
This grant application is a response to Topic 15-OD (ORDR)-101. Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) is an inherited cardiac disease characterized by severe ventricular arrhythmias, as well as progressive replacement of health
STEM CELLS AND THE FIBROBLAST/ADIPOCYTE LINEAGE IN ARRHYTHMOGENIC CARDIOMYOPATHY
DESCRIPTION (provided by applicant): This application addresses broad Challenge Area (04): Clinical Research and specific Challenge Topic 04-HD-102*: Development of Pediatric Medical Devices. Radiation dose in pediatric cardiac interventions is
A LOW-DOSE FLUOROSCOPE FOR PEDIATRIC INTERVENTIONAL CARDIOLOGY
Over the past quarter, we have published one paper titled 'Preclinical derivation and imaging of autologously transplanted canine induced pluripotent stem cells' (Lee AS et la, J Biological Chemistry 2011).  We have also successfully generated
Derivation of Porcine iPS Cells and iPS Cell-Derived Cardiomyocytes
The goals of this project are: 1) Form a Cardiovascular Risk Reduction Learning Community; 2) Electronically collect and analyze data on trajectories of hypertension and LDL-cholesterol control, antihypertensive and hypolipidemic drug prescript
A Cardiovascular Risk Reduction Learning Community in DARTNet
This application addresses broad Challenge Area (05): Comparative Effectiveness Research; Challenge Topic 05-HL-104 Reducing cardiovascular risk in moderate-risk and asymptomatic patients. More than half of the 500,000 coronary artery deaths ea
Predicting Cardiovascular Risk in Vulnerable Plaque Rupture
This application addresses broad Challenge Area 15: Translational Science and specific Challenge Topic 15-RR-101: Applied Translational Technology Development. It is evident that prior to dialysis access failure (thrombosis), access flow decrea
VF DOPPLER SMART SENSOR FOR DIALYSIS AND VASCULAR APPLICATIONS
This application addresses broad Challenge Area (10) Information Technology for Processing Health Care Data and specific Challenge Topic 10-LM-101: Informatics for post-marketing surveillance. The overall goal of this study is to develop a gene
Natural Language Processing to study epidemiology of statin side effects
Preventing Depression in People with Epilepsy:  An Extension of Project UPLIFT Funded by the Centers for Disease Control and Prevention (CDC) as a home-based treatment for depression in people with epilepsy, Project UPLIFT was developed to prov
Preventing Depression in People with Epilepsy: An
This application addresses Challenge Area 15 (Translational Science). Specific Challenge Topic 15-MH-109 Prefrontal cortex regulation of higher brain functions and complex behavior. There is growing emphasis on understanding what might produce
Behavioral Control, the Medial Prefrontal Cortex, and Resilience in the Face of Chronic Stress
NIH Broad Challenge Area 15 - Translational Science NIMH Specific Challenge Topic 15-MH-109 - Prefrontal cortex regulation of higher brain function and complex behaviors. Abstraction is the ability to detect and store the commonalities across e
The Functional Circuitry of Category Learning
Treatment for schizophrenia involves both behavioral and rehabilitation interventions and pharmacotherapy. A number of studies have documented the effectiveness of various interventions and treatments for schizophrenia, but these studies fail t
ECONOMIC PRODUCTION FUNCTIONS OF SCHIZOPHRENIA TREATMENT
As the numbers of older adults with cognitive problems requiring care in this country increase, so does the need for well trained staff.  Assisted living residences are currently estimated to provide care for over two million older adults, with
Uptake of STAR: Increasing Qualified Staff to improve care of older adults in Assisted Living
The objective of this grant is to implement a high throughput screen for small molecules that potentiate the activity of FosB, a transcription factor that promotes resilience and antidepressant-like responses in several animal models and is def
The goal of this project is to validate phosphodiesterase-2 (PDE2) as a pharmacological target for the treatment of mood disorders and to discover novel, selective inhibitors.  Inhibition of PDE2 enhances cGMP signaling by blocking it hydrolysi
Phosphodiesterase-2 and Mood Disorders:  Target Validation and Drug Discovery (RC1)
Children with Autism Spectrum Disorders (ASD) are impaired in their ability to produce and perceive dynamic facial expressions (Adolphs, Sears, and Piven, 2001). Advanced computer vision technologies can now be leveraged in the investigation of
SENSORIMOTOR LEARNING OF FACIAL EXPRESSIONS: A NOVEL INTERVENTION FOR AUTISM
This application addresses Broad Challenge Area (03) Biomarker, Discovery and Validation, with specific Challenge Topic, 03-MH-101, Biomarkers in Mental Disorders. We propose to leverage an ongoing collaboration among faculty from several disci
From Phenotype to Mechanism: Mapping the Pathways underlying Risky Choice
Challenge Area: 14 --Stem Cells Challenge Topic: 14-MH-101*, 'Developing iPS cells for mental disorders' The recent description of somatic cell reprogramming to an embryonic stem (ES) cell-like phenotype, termed induced pluripotent stem (iPS) c
iPS Cell-Derived Neurons Carrying an allelic series of CNTNAP2 structural mutations
Defining of Neurodevelopmental Pathways Regulated by Neuregulin- DISC1 Interactions   Determining if neuregulin 1 (NRG1) signaling modulated DISC1 expression in the developing brain is a goal of this project. Towards this goal, we found that NR
Defining of Neurodevelopmental Pathways Regulated by Neuregulin- DISC1 Interacti
This application addresses broad Challenge Area 03: Biomarker Discovery and Validation, and the specific Challenge Topic 03-MH-101: Biomarkers in Mental Disorders. Attention-deficit/hyperactivity disorder (ADHD) is the most prevalent behavioral
Neuroimaging and Behavioral Biomarkers for ADHD in Children
This application addresses broad Challenge Area (04) Clinical Research and specific Challenge Topic, 04-MH-101, Autism: Addressing the challenge. Although the focus on early identification efforts in recent years has been effective in sharply i
We will identify means to effectively disseminate, adopt and use an established, evidence-based worksite health promotion/injury reduction program for firefighters in 12 departments (~1200 total firefighters) in the Pacific NW. The program is r
IGNITE Investigation to Guide New Insights for Translational Effectiveness
The goal of this proposal is to identify auto-antigens in new autoimmune encephalopathies in human patients, and to determine the effects of patient auto-antibodies on neurons and synapses.  The proposal thus has clinical and basic neuroscience
Synaptic autoimmunity in disorders of memory, behavior, cognition and psychosis
This application addresses broad Challenge Area (15):  Translational Science and specific Challenge Topic, 15-NS-104:  Early-stage Therapy Development.  Amyotrophic lateral sclerosis (ALS, Lou Gehrigs disease) is a devastating neurodegenerative
Transgenic Mouse Models of FUS/TLS-Mediated Amyotrophic Lateral Sclerosis
When stroke patients leave the acute hospital, they travel care paths through various post-acute care sites such as inpatient rehabilitation hospital, skilled nursing facility or home health. However, their families and providers do not have a
Kaiser Permanente Functional Outcomes System
This application is directed to Challenge Area 14, Stem cells, and Specific Challenge Topic 14- NS-101, Reverse engineering human neurological disease: generation of stem cells from control and patient populations. The recent development of ind
STEM CELL DERIVED NEURONS AND INHERITED EPILEPSY
This application addresses broad Challenge Area (15) Translational Science, and the specific Challenge Topic, 15-NS-106: Identifying mechanisms that underlie nervous system development and function. This Challenge solicits mechanistic studies t
MECHANISMS OF A NOVEL CAUSE OF SPINA BIFIDA
LUDWIG INSTITUTE FOR CANCER RESEARCH LTD
This application addresses two Broad Challenge areas (15) Translational Science, including specific Challenge Topics 15-NS-104 (Early-stage therapy development) and 15-NS-103 (Demonstration of 'proof-of-concept') and Broad Challenge area (08) G
ALS Therapies and Genomics for Mutant TDP-43 and TLS/FUS
DESCRIPTION (provided by applicant): This application addresses broad Challenge Area: (06) Enabling Technologies and specific Challenge Topic: 06-MH-103 New technologies for neuroscience research. Develop technologies for neuroscience research
A COMPUTATIONAL FRAMEWORK FOR MAPPING LONG RANGE GENETIC CIRCUITS
DEVELOPING A NORTH AMERICAN MITOCHONDRIAL DISEASE CONSORTIUM This application addresses one broad Challenge Area, (07) Enhancing Clinical Trials (07-OD(ORDR)-102: Rare Disease Genetic Patient Registry. By most epidemiological studies, primary m
Developing a North American Mitochondrial Disease Consortium (NAMDC)
DESCRIPTION (provided by applicant): This application addresses broad Challenge Area (12) Science, Technology, Engineering and Mathematics Education (STEM) and specific Challenge Topic 12-OD-104: Innovative Approaches to STEM Education.    One
Integrating and Evaluating the Modeling Applied to Problem Solving Pedagogy
This application addresses broad Challenge Area of 'Information Technology for Processing Health Care Data' (Area # 10) and two specific Challenge topics (10-RR-101): Information Technology Demonstration Projects Facilitating Secondary Use of H
STATISTICAL INFRASTRUCTURE FOR COMBINING INFORMATION FROM MULTIPLE DATA SOURCES
Science Learning and Scientific Reasoning This application addresses broad Challenge Area (12) Science, Technology, Engineering and Mathematics Education (STEM) and specific Challenge Topic, 12-OD-101: Efficacy of educational approaches toward
(ARRA) Science learning and scientific reasoning
The goal of this 'Grand Opportunities' project is to create a unique and comprehensive population-based resource for research into the genetic and environmental basis of common age-related diseases and their treatment, and factors influencing h
A Resource for Genetic Epidemiology Research in Adult Health and Aging
Staff & infrastructure in place. 107 patients donated blood, oral & fecal specimens; 2,977 aliquots  stored (127 Oral DNA, 183 Fecal DNA); 166 oral & 198 fecal aliquots at MSKCC for analysis; proof-of-concept study has begun; pharmacy dispensin
Role of oral and intestinal microbiota in Rheumatoid Arthritis
Parkinson?s Disease (PD) as well as other neurodegenerative diseases are associated with oxidative damage. In PD, there is an early reduction in reduced glutathione in the substantia nigra, as well as increases in markers of lipid, protein and
Biomarker's of Oxidative Stress in Parkinson's Disease
In this application, we articulate the vision for a center that will integrate recent computational and experimental advances in cancer systems biology toward the genome-wide prioritization of therapeutic targets using high-throughput screening
Systems Biology of Tumor Progression and Drug-Resistance
The CER grant proposal 'Developing Information Infrastructure Focused on Cancer Comparative Effectiveness Research' will aid public health in several ways. First, the development of CER infrastructure will give biomedical researchers a resource
Developing Information Infrastructure Focused on Cancer Comparative Effectiveness
Kaposi’s sarcoma (KS) is a devastating malignancy prevalent among immunosuppressed individuals, including AIDS patients and patients who have undergone organ transplants. The global seroprevalence of KSHV is uneven. It is endemic in sub-Sahar
Immunofocusing for Kaposi’s Sarcoma-Associated Herpesvirus Neutralizing Epitopes
This proposal seeks to apply an innovative, streamlined approach to facilitate the discovery of previously unidentified viral signatures in the several major human cancers from skin, kidney, brain, colon, and the pancreas.  This pilot effort wi
Identifying Novel Viruses in Human Malignancy
Kaposi's sarcoma-associated herpesvirus (KSHV) has been consistently identified in Kaposi's sarcoma (KS) tumors, primary effusion lymphoma (PEL), and Multicentric Castleman's disease. Although classical KS has a low prevalence rate worldwide, t
Live-Attenuated KSHV as Vaccine Candidate
WHO estimates that there are currently more than 30 million people living with HIV/AIDS and there is a great need to develop a safe and effective therapy that requires short-term intervention and long-term control of viral replication. The over
PD-1 BLOCKADE COMBINED WITH VACCINATION AS A THERAPY FOR
We hypothesize that addictive drugs alter cellular lipid pathways in brain and peripheral tissues, and that such alterations influence the transition to compulsive drug use. A corollary of this idea is that peripheral lipid alterations might be
The majority of individuals in criminal justice settings across the U.S. have a critical need for sciencebased, psychosocial treatment that targets substance use and HIV risk behavior. The investigative team has developed and demonstrated the e
Computerized Psychosocial Treatment for Offenders with Substance Use Disorders
Oral cancer, largely oral squamous cell carcinoma (OSCC), is a global health problem afflicting close to 300,000 people each year. Despite significant advances in surgical procedures and treatment, the long-term prognosis for patients with OSCC
MONITORING OF ORAL CANCER PATIENTS USING NOVEL LAB-ON-A-CHIP ENSEMBLES
By coupling a disruptive technology, Digital Micro-Printing (DMP) with advances in miniature, low-cost electronics, the project team will improve access to Point-of-Care ultrasound for Maternal Health thereby reducing healthcare disparities, an
Point-of-Care Ultrasound for Maternal Health
The objective of this project is to develop reliable and reproducible exposure assessment methodologies and protein expression-based methods aimed at the development of biological/ toxicological response endpoints that can serve potential bioma
Characterization Methodologies & Proteomics to Assess Carbon Nanotube Exposure
Plants are the source of many important medicinal compounds and the diversity of plant species and biochemistry suggests that many more are potentially available. The current understanding of the formation of plant-derived medicinal compounds a
TRANSCRIPTOME CHARACTERIZATION OF MEDICINAL PLANTS RELEVANT TO HUMAN HEALTH
.Abstract “Metabolomics Network for Drug Response Phenotype” Response to Recovery Act Limited Competition for NIH Grants: Research and Research Infrastructure “Grand Opportunities” (RC2), RFAOD- 09-004-Linking Metabolomics to Pharmacoge
METABOLOMICS NETWORK FOR DRUG RESPONSE PHENOTYPE
This project seeks to generate new large-scale nationally representative public-use data for the United States that are crucial for conducting scientific and policy-relevant research on (1) immigrant health and mortality and (2) how immigration
GENERATING LINKED NCHS AND OIS DATA FOR IMMIGRANT HEALTH AND MORTALITY RESEARCH
The potential use of nanopores for DNA sequencing has gained significant momentum. This is partly due to innovative solid state techniques, but more so due to breakthroughs using biological pores. One promise of nanopore sequencing has been ver
CONTROLLING LARGE DNA FRAGMENTS DURING NANOPORE SEQUENCING
This application addresses NHGRI RFA-OD-09-004 for Medical Sequencing Discovery Projects. The ultimate goal of this proposal is to scale a new approach to identify the candidate genes and mutations that underlie rare Mendelian diseases in human
Sickle cell anemia is a devastating disease affecting primarily African Americans. Our goals are to capture the genetic diversity that is likely to underlie the notoriously heterogeneous clinical course of this disease, and with this informatio
Red blood cell transfusions are extremely common medical interventions with more than 11 million red blood cell units transfused in the United States and 75 million worldwide. Yet, it remains unclear when patients should receive red blood cell
TRANSFUSION TRIGGER TRIAL IN CORONARY ARTERY DISEASE: A PILOT STUDY
Woody biomass utilization grant: ARRA funds will be used to purchase biomass processing equipment. This equipment will be made available to tribal loggers to work on Reservation and National Forest System lands to process, remove, and supply bi
Order number changed from 09-DO-270-0000173254 due to vendor name change. New order 10-DO-270-0000199044. Contract Support for the Office of Contracting and Personal Property Management
Ortonville to Graceville- bituminous surfacing
2.5 Mi E CSAH 1 to 0.9 Mi E TH 63 - EB Lanes Mill and Overlay
0.4 Mi E of Isanti CSAH 2 to Isanti/Chisago CO Mill and Overlay, incl Shoulder Paving. Line includes replacement of BR 92099 over stream
Fond Du Lac to Gary, Mill and Overlay, Drainage, Lighting
8.6 Mi N of N Jct TH 194 to 2.2 Mi N of Jct TH 33 (NB) and 0.33 Mi N of CSAH 8 to Jct TH 33 (SB), Bridge Repairs to BR 69062 (NB)
Replace Br 6673 over Run River in Milaca
Coordinate Signalized Corridors in District
Replace Timber Bridge No 7445 with 2 Lines of Concrete Box Culvert
Replace Timber Bridge No 7479 with 2 Lines of Concrete Box Culvert
Replace BR 7191 1963 Steel Beam Concrete Deck Structure with three 12'x 8' Box Culverts.
TH 60 to CSAH 18, Widen shoulders and overlay to 10 ton
Replace Timber BR 92467 and Approach Grading over High Island Creek, 4.3 Mi S of Stewart
Jct CSAH 32 (Arrowhead) to Jct CSAH 9 (Martin), Bit Pavement Reclamation
TH 95 interchange, North Branch Reconstruct interchange Apporaches, Frontage Roads, ETC
The Southwest Conservation Corps (SCC) will employ Veterans to complete fire/fuels projects across US Forest Service, San Juan National Forest lands over the next 18-24 months.  The primary work activity will be thinning of hazardous vegetative
Project Title: Humboldt-Toiyabe National Forest Trail Maintenance; Nye and Lander Counties Routine Trail Maintenance will be completed through this agreement on identified trails in the Austin, Tonopah and Ely Ranger Districts, Humboldt - Toiya
Humboldt-Toiyabe National Forest Trail Maintenance; Nye and Lander Counties
Project Title: Spring Mountains National Recreation Area Deferred Trails Maintenance - The overall purpose of this award is to complete trail maintenance and reconstruction on identified trails in the SMNRA. Maintenance activities will include
Spring Mountains National Recreation Area Deferred Trails Maintenance
The award funds services to the Sierra National Forest from the Student Conservation Association's conservation crew program, which recruits, trains and maintains young people to perform environmental and conservation service projects. Within S
The purpose of this award is to implement watershed restoration projects for the Perazzo Meadows Watershed Restoration project.  The Perazzo Meadows system was intensely used and modified during the gold rush and immigration of the late 1800s a
Perazzo Meadows Watershed Restoration Project
TRINITY COUNTY RESOURCE CONSERVATION DISTRICT
Project will treat 181.49 miles of Forest Service roads on Lower Trinity Ranger District of Six Rivers National Forest.
Roadside Vegetation Removal-Six Rivers Brushing Project
Title: ARRA Supplemental Funding for Child Care and Development Fund (CCDF). Description: The CCDF ARRA funds are used to provide child care financial assistance to low-income families on the Tohono O'odham Nation and surrounding communities. F
2009 Child Care and Development Fund Stimulus
OGLALA SIOUX TRIBE OF PINE RIDGE INDIAN RESERVATION
Provide for child care assistance for low-income families.
Money to buy food,we added more salads, fresh fruit and vegetables.
The purpose of this award is to assist the grantee in carrying out a national service program as authorized by the National and Community Service Act of 1990, as amended (42 U.S.C. §12501 et seq.) and in the American Recovery and Reinvestment
The focus of this project is urban environmental education and action.  AmeriCorps members supported with Recovery Act funds provide environmental clubs for elementary students during the summer and into the current school year.  Additionally m
The SCA NH Conservation Corps Award focuses on providing conservation service to the state of New Hampshire through environmental education, public programs, volunteer engagement, and conservation projects on public lands and structures.  The C
RECOVERY NH Commission Competitive Programs
RHODE ISLAND COMMISSION FOR NATIONAL AND COMMUNITY SERVICE
Using AmeriCorps Members and ARRA funds to help restart the Rhode Island economy adversely effected by the 08/09 economic downturn and financial/housing crises.
RECOVERYRECOVERY Rhode Island State Competitive
This grant award represents the annual allocation for FY 2009 to the Tribe for the CSBG Stimulus; ARRA of 2009; made available under Public Law 111-5.
AMERICAN SAMOA SPECIAL SERVICES COMMISSION
AmeriCorps members assist disadvantaged students by tutoring in reading, math, computer skills and mentoring prisoners' families.  AmeriCorps members also eradicate invasive trees.
EXECUTIVE OFFICE OF THE STATE OF INDIANA
AmeriCorps members focus on weatherizing homes, recruiting community volunteers, tutoring children, and assisting non-profits build capacity.
KY Commission Prime for Recovery Act Funding
VOLUNTEERISM & COMMUNITY SERVICES, NC COMMISSION OF
Assisting unemployed and under-employed immigrant and refugee families in accessing social services and employment opportunities in  Guilford County.  Rehabilitating and weatherizing homes to increase energy efficiency, decrease energy costs an
AmeriCorps members assist low income, disadvantaged adults obtain a GED.  Members also assist underachieving elementary school students increase reading proficiency.
Award focuses on, energy-efficient home construction, child abuse and neglect prevention, health education, and direct support for clients.
AmeriCorps members serve as Family Support Workers, providing child abuse prevention services, parent education, and resource and referral support through intensive, weekly home visits with families of young children.
Recovery Child Abuse Prevention Alliance
ARAB COMMUNITY CENTER FOR ECONOMIC AND SOCIAL SERVICES (ACCESS)
The project addresses a variety of human and economic needs resulting from the economic downturn. Project sites have experienced a severe increase in the number of clients seeking services as a result of the economic downturn. Recovery members
AmeriCorps members play a vital role in enabling our partner organizations to meet the growing demand for services at the grassroots level. Members will serve as housing counselors to assist low-income residents avoid foreclosure/ predatory len
This funding provides volunteer support in the NYC K-12 public school system, specifically in low-income communities of Harlem, Washington Heights, and other areas of northern Manhattan. The three primary activities funded by this award include
Recovery Service Fellowship Teacher's College
Recovery Act project agreement #09-RO-11094419-086, to address critical deferred maintenance to 3 1/2 Rd. to improve access the the Pine River Experimental forest.
Recovery Act Road Project Agreement #09-RO-11094419-086
Sucker Brook Hill Drainage Improvement Project. FR 32 (TH 2). Install new culverts, stone line ditches, add guardrail, and resurface road.
Sucker Brook Hill Drainage Improvement Project
Udell Hills Fire Tower Road maintenance and drainage reapir and construction.
cooperative reconstruction project with the Alger County Road Commission and the National Forest Service to resurface buck bay road to the camp ground on autrain Lake.
AmeriCorps members focus on teaching, aiding, monitoring, after-school activities, and bus driving.
OPTIONS - A CHILD CARE AND HUMAN SERVICES AGENCY
ARRA COLA AND QUALITY IMPROVEMENT GRANT. THIS GRANT AWARDS A COST-OF-LIVING ADJUSTMENT OF 1.84% FOR STAFF SALARIES FOR THE PERIOD FROM 7/01/2009 THRU 06/30/2011. FUNDS ALLOW STAFF TO WORK TOWARD OBTAINING A DEGREE
ARRA Cost of Living (COLA) and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act.  Total of 639 children served - 511 children and families in HS and 128 children and families in EHS.  Head St
This award is $399,909 in Cost of Living Adjustment (COLA) and $1,130,004 in Quality Improvement (QI) projects.  The COLA funds affected 467 current employees.  The QI projects had an impact on 30 children directly and another 2,960 indirectly
Head Start Cost of Living Adjustment / Quality Improvement
The award is for Cost of Living Adjustment (COLA) of 1.84% in the amount of $211,610 and Quality Improvement (QI) in the amount of $623,580 for Head Start.
ARRA COLA Quality Grant: The agency serves 433 Head Start and 127 Early Head Start Children in Placer And Nevada Counties in both center based and home based programs.  Funds have been granted for a variety of purposes for our staff and classro
PINAL/GILA COMMUNITY CHILD SERVICES, INC.
ARRA 1.84% COLA and Quality Improvement.  PHS Quality Improvement is for the following: 1) Center Based Teachers to obtain credit hours toward their Bachelors degree 2) Home Based teachers are to obtain their Home Base CDA Credential.  3) Hire
We are in the process of implementing the following: This action awards a cost-of-living adjustment increase of 1.84% in the amount of $17,047 for Early Head Start. These funds will be obligated to pay for staff salaries over the 12 month perio
This award provides for ARRA Cost of Living Adjustment (COLA) and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Early Head Start program.  The Early Head Start program provides hom
The Chicanos por la Causa (CPLC)Early Childhood Development award includes: 1) A cost-of-living adjustment (COLA) increase of 1.84% totalling $11,986 for Early Head Start staff salaries over the 12-month period following the effective date and
This award provides for ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start and/or Early Head Start program. The Children's Institut
This award provides for ARRA Head Start Expansion funds to serve 120 eligible children and families in Stanislaus County.  The Head Start program provides family centered services for low income children (three - five years of age) to promote t
Glenn Highway MP 34.4-40.2, Parks Interchange to Palmer - Rut repair
The purpose of the Public Health Traineeship program is to provide financial support for degree seeking students within the Master of Public Health and doctoral (PhD and DrPH) programs.  Traineeship funding will allow students to concentrate ex
Our proposal for this grant is a new medical facility in Cassville, Missouri.  We have an existing medical facility in Cassville and will be moving it to our new facility.  The current facility is a 1,300 square foot land-locked leased facility
Northwest corner of Fasco Raod and Clover Street
RYAN, WILLIAM F COMMUNITY HEALTH CENTER INC
The CIP funds will be used to improve the Center's infrastructure by renovating the main site and upgrading the facility to improve heating, ventilation, air conditioning, lighting, signage, flooring and several safety features, including the f
VIRGINIA GARCIA MEMORIAL HEALTH CLINIC INC
This award is given to support the implementation of Electronic Health Records throughtout the Virginia Garcia Memorial Health Center (VGMHC)Sites.
To repair/update four existing health Center facilities/equipment to insure patient safety as well as provider efficieny.
ARRA -Capital Improvement Program.  The purpose of this grant was to construct a new medical/dental facility for Stoddard County, Missouri.  The importance of achieving the purpose was to better serve medical and dental patients.
PHMC received a Capital Improvement Project award for its 4 health centers, consisting of 3 projects.  The first project is the renovation of our Mary Howard Health Center.  We will increase the health center from 3,000 square feet to 6,000 squ
A construction project will re-locate the Brooklyn satellite office to a larger more centrally located facility that is now an empty furniture store, in the middle of the Brooklyn community and on a bus line.  The proposed site is more accessib
The purpose of the CIP funds awarded is two-fold: to implement an integrated Patient Management System and Electronic health Record and to help finance a new VolP Phone System which will enable MVHC to effectively communicate within the six-sit
ARRA - Capital Improvement Program funds allowed UCHC to complete the building project for our new health care facility.  ARRA CIP funds were utilized to purchase much needed new equipment for our facility including medical and dental equipment
The name of the grant is Capital Improvement Program. It was used for the Sequoia Circle Facility Renovation Project. The goal was to renovated the aging exterior of the facility. These renovations removed the dry rot on the exterior, replaced
Capital Improvement Program: Sequoia Renovation Project
NORTHEAST WASHINGTON COUNTY COMMUNITY HEALTH INC
ARRA-Capital Improvement Program/Dental and General Facility Renovation. The primary purpose of this dental and facility renovation project was to expand our dental capacity through the renovation of undeveloped space in the lower level of our
Our capital improvement projects include renovation of two buildings. Our 754 Walnut Street building has been renovated to accomodate a new Pediatrician and a Mental Health Professional with 4 treatment rooms and a laboratory.  In our 770 Walnu
CHATTANOOGA HAMILTON COUNTY HOSPITAL AUTHORITY
ARRA Capital Improvement Program (CIP) grant funding- Project Name: Renovate Dodson Avenue Community Health Center. Purpose: to renovate and upgrade the physical plant and services offered. Project Goals: expand clinical area by 4 exam rooms an
ARRA CIP Renovations to Dodson Avenue CHC
Sarasota County Health Department/Northport Federally Qualified Health Center Capital Improvement Project  The purpose of this grant is to supplement the cost to renovate the existing facility and expand the building by approximately 5,000 squa
ARRA - Capital Improvement Program - Sarasota County
Grant Name is Capital Improvement Program.  Purpose of this grant is to support the renovation of approximately 2,500 square feet of clinic space, creating 500 sq. ft. of entry and waiting room space to enable the Health Center to appropriately
Award Description: The Capital Improvement Award is to implement an Electronic Health Record and Practice Management System, and to upgrade out dated medical, dental and communication equipment. The award will be used to purchase and installing
Severe asthma, a heterogeneous disease consisting of related clinical phenotypes, generates high levels of morbidity, mortality and health care costs. The complexity and heterogeneity of the disorder have limited clinical advances. However, the
Linking Genetics, Genomics and Phenomics to Better Understand Asthma Severity
We have developed a safe and effective transplant approach for both matched sibling and haploidentical related transplants which addresses the problem of donor availability in patients with leukemia, lymphoma, and related disorders. This approa
Matched and Haploidentical transplantation for Adults with Sickle Cell Anemia
The goal of the proposed work is the development of novel approaches to the stimulation of fetal hemoglobin (HbF) production in red blood cells of adults. HbF is a known modifier of the severity of the major hemoglobin disorders, sickle cell an
Extending GWAS at the BCL11A locus to novel therapeutics for HbF induction
This project addresses the NHLBI RC2 GO application entitled 'Characterizing Differentiated Heart, Lung, and Blood Cells Derived by Reprogramming Human Embryonic and Induced Pluripotent Stem Cells.' Emerging technologies to generate induced plu
HEMATOPOIESIS FROM NORMAL AND PATIENT-DERIVED INDUCED PLURIPOTENT STEM CELLS
This application from the Institute for Health Metrics and Evaluation addresses NHLBI Participation in NIH Research and Research Infrastructure 'Grand Opportunities' (RC2) (RFA-OD-09-004); NHLBI RC2 topic area 'Novel Methods of Measuring Health
Novel Methods of Measuring Health Disparities
Heart failure affects more than 5 million Americans, and strikes over 500,000 new patients each year. Due in the majority of instances to dilated or ischemic cardiomyopathies, heart failure is a classic 'complex disease', i.e. it is multi-facto
CTRIP: GENETIC TESTING TO INDIVIDUALIZE MANAGEMENT OF COMMON HEART DISEASES
This application addresses the National Center on Minority Health and Health Disparities' (NCMHD's) Social Determinants of Health Initiative high priority area for funding under the NIH Research and Research Infrastructure Grand Opportunity. Th
We propose to collect and analyze the first ever whole exome sequence data from  patients with schizophrenia (SCZ, n > 118), bipolar disorder (BPD, n > 118) and  controls (n >116). By providing the first comprehensive evaluation of coding  vari
Whole genome sequencing of bipolar disorder and schizophrenia
The primary goal of this proposal is to develop and implement an innovative consumer research network (CRN) that can advance the research in the science of improving health by creating a consumer based health information technology (HIT) infras
DEVELOPMENT OF A CONSUMER RESEARCH NETWORK FOR STUDYING OBESITY
1.0This application Abdominal Symptom Phenotype: Pathways to New Biomarkers (ASPPNB)is in response to RFA-OD-09-004, American Recovery and Reinvestment Act for research and infrastructure. This application is responsive to NINR priorities relat
Abdominal Symptom Phenotypes: Pathways to New Biomarkers.
This application addresses broad Challenge Area (03) Biomarker Discovery/Validation and specific Topic 03-MH-101: Biomarkers in Mental Disorders. The proposed research takes a construct-oriented approach to the identification of biomarkers for
Trait Fear and Disinhibition in Impulse Control Disorders
Title: Prostacyclin-secreting Cells as Therapy for Pulmonary Artery Hypertension  Description: Pulmonary arterial hypertension is a rare but fatal disease, and current therapies are not curative and are associated with significant drawbacks. As
Prostacyclin-secreting Cells as Therapy for Pulmonary Artery Hypertension
The specific Aim of this 2 year project is to characterize the UPR induced by CS in several lung cells involved in the pathogenesis of COPD, i.e., airway epithelial cells and alveolar pneumocytes.  We will test the hypotheses that: 1) the UPR r
The Unfolded Protein Response in Human Airway and Alveolar Epithelial Cells
DESCRIPTION (provided by applicant): The instrument described in this application is a matrix-assisted laser desorption ionization (MALDI) tandem time-of-flight (TOF/TOF) mass spectrometer. The proposed instrument will be a part of the shared m
Tandem Time-of-Flight Mass Spectrometer for Proteomics
The instrumentation will facilitate biomedical research in three research centers at The University of Montnan with focuses in neurobiology, environmental health, and biomolecular structure and dynamics, respectively.  NIH-funded investigators
Olympus FV1000 Scanning Confocal-TIRF Imaging Workstation
The long-term goal of this proposal is to advance our knowledge by employing imaging techniques using small animal MicroCT (Inveon MicroCT). This instrument has high resolution (27 microns) and will be most suitable for small animal investigato
A shared FTMS instrument upgrade to further biomolecular research at UIC.  The instrument is used at the Proteomics and Infomatics Facility at the Research Resources Center.
A shared FTMS Instrument Upgrade to further Biomolecular Research
Acquisition of a Bruker X8 Prospector Protein X-ray Crystallography System
Acquisition of a Bruker X8 Prospector Protein X-Ray Crystallography System
MOUNT SINAI SCHOOL OF MEDICINE OF NEW YORK UNIVERSITY
Currently, the functional neuroimaging research conducted and supported by the Laboratory of Neuroimaging at the Mount Sinai School of Medicine utilizes fMRI as a primary measure. fMRI is the hallmark of spatial resolution amongst functional ne
A 500 MHz solid-state NMR spectrometer is requested in order to replace an aging 360 MHz NMR instrument that was purchased in 1989. This NMR instrument currently supports four areas of NIH-funded biomedical research at Stony Brook University th
ARRA: 500 MHz Solid-State NMR Spectrometer
The aim of this proposal is for the Case Western Reserve University (Case Comprehensive Cancer Center) to acquire an imaging cytometer, the Amnis ImageStream to expand the flow cytometry capabilities at the Case Comprehensive Cancer Center, Cas
Amnis Imagestream for Case Comprehensive Cancer Center
This award supports acquisition of an animal neuroimaging package which will allow us to adapt a brand new state-of-the-art human 3 Tesla MRI scanner for small animal neuroimaging.   We will obtain customized rat and mouse coils fully compatibl
ASmall animal module for translational MR Neuroimaging at3 Tesla
For applications in biodefense, it is desirable for small molecule inhibitors to target multiple category A-C agents because it is difficult and expensive to develop even one small molecule inhibitor. We propose to develop inhibitors of Hollida
BROAD SPECTRUM THERAPEUTICS TARGETING RESOLVASE ENZYMES
Small animal models of infectious disease play a central role in research programs aimed at identifying leads and approaches that could be exploited to devise improved diagnostics, pre-treatments and therapies against bioterrorism agents. Howev
NON-INVASIVE OPTICAL IMAGING OF SELECT AGENT BACTERIA IN NON-HUMAN PRIMATES
In this project, we will engineer Morburgvirus glycoprotein GP for high-leve,. homogeneous expression, and crystallizability. Any crystals obtained will be tested for X-ray diffraction, with the ultimate goal of provision of a crystal structure
Immunotherapeutics Against Marburg: Development, Structural and Functional Analysis
The Bureau of Primary Care, housed within the DC Department of Health's Community Health Administration, has, as the designated state Primary Care Office, been awarded ARRA funding to support its functions related to ?Workforce Development for
Federal support assists the Kansas Primary Care Office in its work with the National Health Service Corps and Underserved Areas Designation through supplementing existing federal support for the activities of the Primary Care Office under its c
One of the major unsolved problems in drug delivery is how to transport poorly permeable molecules across membrane barriers. The way that Nature solves this problem is through membrane trafficking; cell impermeable ligands such as the iron-carr
Synthetic Cell Surface Receptors for Anticancer Drug Delivery
Considerable advances have been made in the study of opioid receptor structure and function, and in recent years evidence has accumulated that opioid receptors can interact with one another. Early studies demonstrated that antagonism of delta o
The proposed studies are focused upon identifying and inhibiting the pathogenic process by which a high-fat or western-style, diet evokes Type 2 diabetes, using the mouse model of this common mammalian syndrome. Preliminary work completed suppo
Glycosyltransferase Function in Development and Disease
Inflammatory bowel disease (IBD) is a chronic inflammation of the GI tract that includes Crohn's disease and ulcerative colitis. The major enzymes involved in mediating the inflammatory response in IBD are cyclooxygenase (COX), lipoxygenase (LO
In Vivo Investigations Using Microdialysis Sampling
The This task order request is composed of four (4) individual tasks.  This task order request will have four (4) individual descriptions for this section of the RFTOP.  Task 1: The purpose of this task order is to obtain technical assistance a
Community Health. FluMist to be provided under the VFC program.
The overall purpose of the ARRA funds received by Merck is to provide the CDC Project grantees vaccines for their respective Immunization Programs.  In some instances, the ARRA funds will provide vaccines that would cover a budget shortfall in
SPRING VALLEY/COIT ROAD PEDESTRIAN AMENITIES
FM 732 Fr. AT FM 732 0.10 MI N LONG LN NEW LOC To. 0.12 MI S OF US 77/83 EXPWY;  CONSTRUCT 2 LANE RURAL W/ SHOULDERS (RELOCATE FM 732)
Pavement & Rehabilitation, South II-II, 2009
Pavement & Rehabilitation, North XI, 2009
Peak Vista received a Capital Improvement Program (CIP) grant in the amount of $1,880,475 focused on three Alteration/Renovation and Equipment projects for our clinics. Project 1 was an Alteration/Renovation project. This project allowed us to
ARRA Capital Improvement Program grant funds have enabled LSCHC to reach its? goals of information technology (IT) infrastructure upgrades and expanded Electronic Health Record (EHR) capacity.  The IT, EHR and equipment acquisitions and upgrade
Capital Improvement Program.  The purpose and goals are: To consolidate two small clinics into one larger state-of-the-art health center and to purchase a mobile medical unit for a healthier community.
Grant Name is ARRA - Capital Improvement Program.  The purpose of the funds are to construct a new facility for the medical clinic at our service site in Cleveland, Texas so that more patients can be seen.  The current facility has only 3 exam
The purpose of this award is to made capital improvements to the existing building of Centro de Salud Familiar Dr. Julio Palmieri Ferri Inc. The center will undergo renovation of the onsite pharmacy, main patient waiting room and patient regist
The Capital Improvement Program (CIP) was awarded to Central Virginia Health Services by the Health Resources and Services Administration of the Department of Health and Human Services.  A total of 10 projects were devised by CVHS to expend the
COMMUNITY HEALTH CENTER OF BUFFALO, INC.
ARRA - Capital Improvement Program: The program scope has been revised and CIP funds will be used to underwrite part of the cost of renovating a 49,000 sq. ft. building to allow the Community Health Center of Buffalo, Inc. (CHCB) to increase ac
ARRA - Nurse Faculty Loan Program (NFLP) - Wayne State University will issue loans to eligible students for the cost of tuition, fees, books, lab expenses, and other reasonable education expenses.
ARRA funds with NFLP to enable 5 more students to pursue their goal of becoming nurse educators
Ruth L. Kirschstein National Research Service Award (NRSA) for Individual Postdoctoral Fellows (F32) award. This NRSA mechanism provides a stipend, tuition and fees, and an institutional allowance.The purpose of this award is to provide support
Electron microscopy studies of novel poliovirus genome-releasing intermediates
How do amoebae detect and kill bacteria?  Free-living amoebae prey upon diverse species of microbes in nature, including some that infect humans.  The antagonistic dynamics of this process—microbial resistance and amoeba counter-resistance—
Evolution and Genetics of Bacterial Recognition by Amoebae
Coxiella burnetii is a Gram-negative, obligate intracellular bacterium that is the causative agent of Q-fever in humans and is further classified as a Class B select agent. After uptake by a host cell, C. burnetii subverts specific host cell pr
A systems Biology Approach for Investigating Coxiella Burnetii Infection
The Community Health Access Network (CHAN) is the only Health Center Controlled Network (HCCN) in New Hampshire.  Established in 1995, CHAN has developed an integrated clinical and administrative system infrastructure for its five Federally Qua
EHR implementation and workflow optimization for Health Choice Network of Utah's 8 delivery sites.
This program is designed to provide $25,000 per year loan repayment funding to physicians who practice full time primary care or psychiatry in rural and underserved Georgia counties that are also Health Professional Shortage Areas as defined by
EXECUTIVE OFFICE OF THE GOVERNOR OF DELAWARE
The purpose of the ARRA 2009 State Loan Repayment Program (SLRP) funding opportunity is to support Delaware's well established program to achieve an appropriate number and geographic distribution of health professionals in Delaware, with a part
The original NAP grant was submitted in December 2007 when the Daily Planet managed an existing site, Craig Health Center (CHC), which did not receive Federal funding.  Unfortunately because of financial reasons Craig Health Center cl
ARRA Increase Services to Health Centers CAMcare Health Corporation received $457,223 in ARRA funds to increase and expand existing comprehensive primary medical and dental healthcare services in South Jersey to improve the health status of the
Increase services to Health Center clients
ARRA-Increase Services to Health Centers. Increase staff in the areas of Mental/Behavioral Health, Information Technology, and Support Staff (Billing and Reception).
Our focus is to improve OB/GYN services for the female population in our area. We did this through recruitment of additional staff to provide these needed services.
COMPREHENSIVE COMMUNITY HEALTH CENTERS, INC
NEED: The Federal government as well as the State of California and the City and County of Los Angeles have large budget deficits which are being closed by reduction of services and layoffs.  Unemployment remains high projections now show Calif
Expansion of patient care services and employment
ARRA - Increase Services to Health Centers (IDS)
ARRA - Increase Services to Health Centers - The 3 care coordinators who were hired 7/2009, with the help of IDS funds, have now generated a total of 1679 face-to-face enabling encounters, and made an additional 5191  telephone contacts with pa
ARRA - Increase Services To Health Centers
SOUTHEAST MISSISSIPPI RURAL HEALTH INITIATIVE INC
ARRA Increased Demand for Services funding was awarded to Southeast Mississippi Rural Health Initiative, Inc. to create jobs and improve access to care for underserved patients.  Many patients in the area have lost jobs and health insurance cov
In response to a very poor economy nationwide, the Health Resources and Services Administration awarded funds to Community Health Centers for the purpose of meeting increased demand for services with increased capacity to deliver primary health
ARRA-Increase Services to Health Centers or Increased Demand for Services (IDS) Grant was originally submitted and approved to retain or hire 5.25 FTE Employees and help increase the staff, Extend the hours of operation and Expand existing serv
Increase Services to Health Center of Southeast Texas
TRI COUNTY COMMUNITY HEALTH COUNCIL, INC
TCCHC will utilize IDS funding to address staffing difficulties that has arisen from the continuing economic crisis of 2008. As a result of reduction in revenue by delayed payments from State funding sources and third party insurances, decreas
DAVID RAINES COMMUNITY HEALTH CENTER, INC.
The project would provide resources to increase health center staff by funding the currently unfilled provider positions of physician and licensed clinical social worker. It is anticipated that the physician would provide services to the rural
The goal of ARRA IDS fund usage is to expand access for our target population through a number of actions, including 1) expansion of clinic hours at existing sites where space is available (medical and dental), 2) expansion of pharmacy services
ARRA - Increase Service to Health Centers
Conflict between the sexes over control of fertilization is expected to be widespread among organisms, but its evolutionary consequences are still poorly understood particularly in vertebrate animals. Waterfowl have complex breeding systems tha
The majority of proxy temperature records indicate that during the early Pliocene, roughly 3 to 5 million years ago, the tropical Pacific was characterized by a permanently warm El Nino-like mean state. Specifically, the sea surface temperature
HISTORIES OF SOCIAL ENGAGEMENT & COGNITIVE FUNCTIONING   Research has suggested that greater social engagement – a term used to refer broadly to both quantitative and qualitative aspects of social interaction – is associated with significan
HISTORIES OF SOCIAL ENGAGEMENT & COGNITIVE FUNCTIONING
Because Gram-positive (G+) infections are common and can be life-threatening, it is critical to have a thorough understanding of how these pathogenic bacteria and the various molecules that they release interact with the host immune system. One
Activation of Macrophages by Lipoteichoic Acid
In 2008 more than 200,000 American women will be diagnosed with breast cancer and many will be treated with antiestrogens. Unfortunately, many breast tumors initially respond to antiestrogens will become unresponsive over time, leading to metas
Molecular mechanism of ID1 function in advanced breast cancer
Aim 1. Determine the mechanisms governing DACH1/Eya inhibition of breast tumor cellular proliferation. We will determine the DACH1 binding proteins governing breast tumor growth we will characterize these components in human breast cancer and i
DACH1/Eya cell-fate Determination Factor and Mammary Tumoregenesis
To trim the previous 5-year project (lR01EY018380-1A2) for the 2-year funding by the ARRA, here, we propose to test our hypothesis by conduct the following studies. First, we will use molecular and biochemical methods to identify the binding si
Regulation of Apoptotic Signaling Pathways by Alpha-Crystallins in the Ocular Lens
Proper functioning of the cell cycle and its regulation in response to both internal and external stimuli is essential for the normal growth, division, and differentiation of cells and tissues. One of the regulators of cell cycle progression is
Pseudosubstrate inhibition of the anaphase promoting complex
This is an efficacy study of an intensive home visitation intervention, ''''Minding the Baby'''' (MTB). This reflective parenting program (aimed at enhancing maternal reflective capacities), is focused on first-time young mothers and their infa
Minding the Baby: home visiting program evaluation
Title:  Community-Based Lifestyle Promotion with Latino Women  The purpose of this study is to evaluate the feasibility and outcomes of a community-based healthy lifestyle behavior intervention (LSBI), delivered by promotoras, to middle-aged La
COMMUNITY-BASED LIFESTYLE PROMOTION WITH LATINO WOMEN
METABOLIC OSCILLATIONS IN HEART  Efficient coupling of energy production to energy needs is critical for the beating heart, and factors disrupting this relationship are likely to promote injury.  Glycolytic oscillations have been characterized
EUREKA Award: Preventing the Incidentalome. The project's scope is to determine whether mutations commonly thought to be pathogenic are in fact not so in the general population.
The collection of newly discovered clinically valuable genetic tests is far outpacing our ability to use clinical trials to determine their clinical efficacy and determine which of the collection of tests and associated algorithms are best suit
Method for Prediction of Efficacy of Genetic-based Prediction Models of Personalized Medicine with Clinical Avatars
BCL-xL is the major anti-cell death BCL-2 family member expressed in brain, and understanding its function is key to designing strategies for neuroprotection. In this application, we will attempt to prove that inhibition of BCL-xL or down regul
Role of BCL-xL in Synaptic Plasiticity in the hippocampus
This is a multi-PI RO1 grant designed to use multiple mouse genetic models of neural tube defects (NTDs, spina bifida and anencephaly) to investigate genetic factors confering NTD risk. Investigations will study how those gene mutations interac
Genetic Predisposition & Prevention of Neural Tube Defects
J & S I Weill Medical College of Cornell Univ
Cardiovascular disease (CVD) is the leading cause of death in the western world. However, why some individuals with identical risk factor profiles will go on to develop CVD, whereas others will not, is simply not understood. One explanation is
MITOCHONDRIAL ASSOCIATED CVD SUSCEPTIBILITY IN HUMANS AND MICE
Exposure to ultraviolet radiation (UVR) is one of the primary modifiable risk factors for development of melanoma with exposures occurring early in life believed to be most critical. The relationship between UVR exposure and family history has
SUN PROTECTION AMONG CHILDREN WITH A FAMILY HISTORY OF MELANOMA
The overarching goal of this study is to test the role of pain, illicit drug use, and symptoms of depression and anxiety in the misuse of opioids and psychoactive medications within an existing cohort of men who have sex with men (MSM) particip
PAIN, PSYCHOLOGICAL SYMPTOMS, AND PRESCRIPTIONILLICIT DRUG USE IN THE MACS
MicroRNAs are a new class of non-coding small RNAs that negatively regulate gene expression by either degrading mRNA or suppressing protein translation. A miRNA cluster, miR-15/16, has been implicated in a variety of human diseases, such as can
Transgenic rat overexpressing miR-15/16 cluster:functional implications in develo
Before sperm are able to successfully fuse with and fertilize the egg they must successfully migrate through the female reproductive tract and reach the ovulated oocytes. During this migration the sperm undergo Capacitation - defined as the abi
CALIFORNIA STATE UNIVERSITY AUXILIARY SERVICES, INC
The rapid and accurate diagnosis of bacterial pathogens causing diseases and infections has been a goal of clinicians and microbiologists since the discovery of microbes as disease-causing agents. Conventional methods of diagnosis rely upon phy
Label-Free and Simultaneous Detection of Multiple Bacterial Pathogens and Virulen
The purpose of this grant application was to screen chemical and small interfering RNAs (siRNA) libraries to identify chemical probes and siRNAs that modify three distinct arms of IERSR. The probes generated through this effort will be critical
Molecular and Chemical Biology of Integrated ER Stre
Trypanosomes and related protozoa cause a variety of debilitating diseases in the tropics including Human African Sleeping Sickness, Chagas Disease and various forms of Leishmaniasis.  The goal of our work is to study pathways present in the pa
TRANSLATIONAL PARTITIONING OF THE SL RNA
Trypanosomes and related protozoa cause a variety of debilitating diseases in the tropics including Human African Sleeping Sickness, Chagas Disease and various forms of Leishmaniasis.  In the mammalian hosts, regulated gene expression is determ
GLOBAL SUMOYLATION ANALYSIS IN TRYPANOSOMA BRUCEI
Polymorphonuclear Phagocytes in Malaria Sepsis, Award Number R21AI080907 from the - Institute of Allergy and Infectious Disease, is aimed at investigating that the Myeloid Differentiation Factor 88 (MyD88), an adaptor-signaling molecule for the
Role of Polymorphonuclear Phagocytes in Malaria Sepsis
This project is aimed at developing a novel approach that quantifies autoantibodies against multiple prostate cancer associated antigens in conjunction with a classic biomarker, PSA.  This novel approach may find broad applications in prostate
AUTO-ANTIBODY PLUS PSA ASSAY FOR PATIENTS WITH PROSTATE CANCER
Approximately 90% of all deaths from breast cancer arise from metastatic spread of a primary tumor. The failure of current cancer treatment may be explained by a small subset of therapy-resistant and highly metastatic cancer stem cells (CSCs).
In vivo molecular laser detection of circulating cancer stem cells
Chronic pain disorders may persist in children and adolescents for several years and have significant impact on their physical, social, and academic functioning, with potential long-term reduction in quality of life.  A significant obstacle to
PEER MENTORSHIP: AN INTERVENTION TO PROMOTE EFFECTIVE PAIN SELF-MANAGEMENT IN ADOLESCENTS
Allergic diseases such as contact sensitivity and delayed type hypersensitivity can be very debilitating and are a rapidly increasing and costly burden on public health systems in the United States. This proposal will develop new technology to
This research is a feasibility study that is organ specific and is aimed at determining the ability of a dedicated breast computed tomography system (herein, referred to as breast CT system) to visualize lesions.  Specifically, this research is
The UCLA Racial and Ethnic Minority (REM) HIV/AIDS Translational Training (HATT) Program.   Our R25 training grant has developed a research mentorship program for REM postdoctoral fellows and early career investigators interested in studying HI
HIV/AIDS:TRANSLATIONAL APPROACHES AND HEALTH DISPARITIES
DETECTING ANTIDEPRESSANT RESPONSE TRAJECTORY SHAPES IN THE STAR*D COHORT
Title: Evaluating an emergency department observation syncope protocol for older adults   This application addresses the broad Challenge Area (05): Comparative Effectiveness Research, and specific Challenge Topic: “05-AG-104. Planning grants
EVALUATING AN EMERGENCY DEPARTMENT OBSERVATION SYNCOPE PROTOCOL FOR OLDER ADULTS
Identification of Enhancers of Therapeutic Exon Skipping for Duchenne Muscular Dystrophy Duchenne Muscular Dystrophy (DMD) is the most common lethal genetic disease of childhood, occurring in 1 in every 3500 live male births. It is caused by th
IDENTIFICATION OF ENHANCERS OF THERAPEUTIC EXON SKIPPING FOR DMD
The awarded grant monies will be used to purchase in car camera systems for both the police and sheriff's office.
Supplemental Digital Mobile Recording Enhancement Project
The grant is to be used for the purchase of a number of in-car video systems for marked patrol units.
Obtaining Evidence and Enhancing Professionalism
The Town of Windsor will use it's Fiscal Year 2009 Recovery Act JAG award to improve traffic.  Specifically the JAG funds will be used to purchase three hand held radar guns, one solar powered speed trailer, and funding for one traffice officer
BJA FY 09 Recovery Act Edward Byrne Menorial Justice Assistance Grant Program Local Solicitation
The Edward Byrne Memorial Justice Assistance Grant (JAG) provides funding to support all components of the criminal justice system. The JAG program allows local governments to support a broad range of activities to prevent and control crime bas
Edward Byrne Memorial Justice Assistance Grant (JAG) Program FY 2009 Local Solicitation
ALASKA NATIVE WOMEN'S COALITION AGAINST DOMESTIC VIOLENCE SEXUAL
Tribal Coalition to work with Alaska Tribes on domestic violence and sexual assault issues.
First Nations Women's Alliance will utilize American Recovery and Reivestment Act Funding to enhance the response to violence against Native American Women by training law enforcement and the Tribal Judicial Systems on North Dakota Tribal Lands
First Nations Women's Alliance Tribal Domestic Violence and Sexual Assault Coalition Program
The Maine Coalition to End Domestic Violence (MCEDV) Recovery Act Project encompasses two interlocking initiatives that support and expand the capacity, responsiveness, and accountability of MCEDV, our member programs and other organizations wh
Maine Coalition to End Domestic Violence Recovery Act Project
COLORADO COALITION AGAINST DOMESTIC VIOLENCE
Goal 1:  Improve the capacity of local domestic violence member programs to provide safe and effective services to victims and survivors. Objective 1:  Increase the CCADV Membership Services Coordinator position from its current 0.5 FTE to 1.0
State Domestic Violence Coalition Economic Stimulus Project
MILITARY AFFAIRS AND PUBLIC SAFETY, WEST VIRGINIA DEPARTMENT OF
STOP Violence Against Women Recovery Act Grant funds are used to support communities in their efforts to hire and retain criminal justice and victim service personnel which respond to violent crimes against women (Stalking, Sexual Assault, Dome
Stop Violence Against Women Recovery Act
PUBLIC SAFETY, MISSISSIPPI DEPARTMENT OF
This award provides the opportunity for recipients to develop and strengthen effective responses to violence against women.
The S.T.O.P. Violence Against Women Recovery Act Program encourages the development and/or enhancement of effective strategies and services to improve the criminal justice system's response to violence against women.
LAW ENFORCEMENT & CRIMINAL JUSTICE COMMISSION NEBRASKA
The 2009 ARRA VAWA project will be utilized according to the approved VAWA Implementation plan and required percentage set asides for courts, victim services, law enforcement, prosecution and discretionary.  Nebraska's priorities include fundin
OVW Recovery Act STOP Violence Against Women Formula Grant Program
The Transitional Housing Assistance Program grant funds will be used to support programs that: a) provide transitional housing, including funding for the operating expenses of newly developed or existing transitional housing; b) provide short-t
OVW Recovery Act Transitional Housing Assistance Grants for Victims of Domestic Violence, Dating Violence Stalking, or Sexual Assault
ARRA Fund  for transitional housing will provide assistance and related support services to minors, adults, and their dependents that are in need of transitional housing or other housing assistance, as a result of fleeing a situation of domesti
LOS COYOTES BAND OF CAHUILLA AND CUPENO INDIANS
Award from Office of Violence against Woman for Tribal Governments to create the Cahuilla Tribal Consortium encompassing three tribes: The Los Coyotes Band of Cahuilla and Cupeno Indians, Cahuilla Band of Indians and the Santa Rosa Band of Indi
Develop resources to assist victims of domestic violence, dating violence, sexual assault, and stalking to overcome barriers that prohibit them from obtaining and/or maintaining employment or academic success. Provide victims with the opportuni
Nami Migizi Nangwiihgan Domestic Violence Services
To provide safe, viable options, services and support to persons exposed to domestic violence, sexual assault and stalking. Services include, 24 hour shelter, housing assistance, transportation and assistance with the filing of protection order
Hearts of Hope Domestic VIolence/Sexual Assault Program
The Grand Traverse Band of Ottawa and Chippewa Indians (GTB) Sexual Assault Response Team (SART) Project provides the opportunity to develop & strengthen effective responses to violence against women. The part-time domestic violence police offi
Grand Traverse Band of Ottawa and Chippewa Indians (GTB) Sexual Assault Response Team (SART) Project
Program Support for Transitional Housing in Dona Ana County, NM
This award supports CORA's Expanded Transitional Housing Program. This program will povide transitional housing services, short-term housing assistance and related support services to victims of domestic violence. Major deliverables include cre
CORA's Expanded Transitional Housing Program
Grant funds will continue to serve surviving  victims of Domestic Violence. The funds awarded have been used to increase the availability of transitional housing for victims of domestic violence, dating violence, stalking, and sexual assault. A
The Safe Path Project will provide 11 units for Portage County adult victims of domestic violence and their children; thus allowing options for affordable, safe transitional housing with supportive services.  The project will both create and re
Project HAP: Housing Assistance Program and Supportive Services for Victims of Domestic Violence in Crittenden County and St. Francis County, Arkansas.
Project HAP: Housing Assistance Program and Supportive Services for Victims of Domestic Violence.
This award provides the opportunity for recipients to develop and strengthen effective responses to violence against women. This grant will support the reciepient's efforts in promoting economic recovery by employing victim advocates and other
Recovery Act Transitional Housing Assistance Grant
The 2009 Recovery Act Grant will allow the Indigenous Women's Life Net program of the Minneapolis American Indian Center to provide transitional housing resources and services for women who are fleeing from domestic violence, or/are victims of
My Sisters House Transitional Living Program proposes to serve pregnant of parenting young women age 16-21 who are homeless and who are the victims of domestice violence, dating violence, stalking or sexual assault.  Residential transitional li
My Sister's House Transitional Living Program
UTAH COALITION AGAINST SEXUAL ASSAULT, THE
The OVW Recovery Act statewide sexual Assault Coalitions provide direct support to member rape crisis centers through training and technical assistance, public awareness activities, and public policy advocacy.
OVW Recovery Act Grants to State Sexual Assault And Domestic Violence Coalitions
MISSISSIPPI COALITION AGAINST SEXUAL ASSAULT, INC
The OVW Recovery Act statewide sexual assault coalitions provide direct support to member rape crisis centers through funding, training and technical assistance, public awareness activities, and public policy advocacy (e.g., state coalitions mi
OVW Recovery Act-Grants to State Sexual Assault and Domestic Violence Coalitions Program
Collaborate and coordinate with Federal and Territorial entities engaged in prevention of violence against women activities under the American Recovery and Restoration Act.
Recovery Act  STOP Violence Against Women
IDAHO COALITION AGAINST SEXUAL AND DOMESTIC VIOLENCE INC
OVW Recovery Act Grants to State Sexual Assault and Domestic Violence Coalitions Program.  Idaho Coalition Against Sexual & Domestic Violence Recovery Initiative will create/retain jobs and stimulate the economy through enhancement of education
Idaho Coalition Against Sexual & Domestic Violence Recovery Initiative
SOUTH DAKOTA COALITION AGAINST DOMESTIC VIOLENCE AND SEXUAL ASSAULT
OVW Recovery Grants to State Sexual Assault and Domestic Violence Coalitions. To preserve and create jobs and promote economic recovery; to assist those most impacted by the recession; to provide investments needed to increase economic efficien
South Dakota Coalition Against Domestic Violence and Sexual Assault
OKLAHOMA COALITION AGAINST DOMESTIC VIOLENCE AND SEXUAL ASSAULT, INC
The project funded 1.5 fte employees including data management specialist and part time librarian. The grant provided full payment for life, medical, dental insurance premiums.  The Librarian is now a .75 fte employee and funded under 2 other g
TENNESSEE COALITION AGAINST DOMESTIC AND SEXUAL VIOLENCE
Funding under this Program was used to retain two jobs that would be lost without additional funding, a Program Specialist and a Meetings and Trainings Coordinator. The Program Specialist provided training, technical assistance and information
Tennessee Domestic and Sexual Violence Coalition Economic Recovery Project
Tribal Community Services Block Grant Stimulus
ARRA Supplemental Funding for the Child Care and Development Fund (CCDF); Provide child care financial assistance to low-income working families and fund activities to improve the quality of child care.
ARRA Supplemental Funding for the Child Care and Development Fund (CCDF)
Assit low income families to pay for child care services and to improve the quality of child care services offered.
ARRA Supplemental Funding for the Child Care and Development Fund (CCDF):  Provide child care financial assistance to low-income working families and fund activities to improve the quality of child care.
The Maryland State Department of Education received funds through the American Recovery and Reinvestment Act of 2009 (ARRA) to assist in the purchase of equipment for School Food Authorities (SFAs) participating in the National School Lunch Pro
This application addresses Broad Challenge Area (09): Health Disparities and Prevention and Specific Challenge Topic, 09-CA-101: The Basis for Differences in Cancer Incidence. There is an established disparity in stage-specific outcomes in Afri
Occult lymph node metastases and racial disparities in colon cancer outcomes
Using agent-based modeling to develop a robust and well-characterized model of individual-level nutrition and physical activity behaviors, as influenced by social and physical environmental factors.
STIMULUS: AGENT-BASED MODEL OF INDIVIDUAL-LEVEL FOOD CHOICE AND PHYSICAL ACTIVITY BEHAVIOR
This project directly addressed the broad Challenge Area (06) Enabling Technologies and specific Challenge Topic: Chemist/Biologist collaborations facilitating tool development.  The goal of this project is to target the N linked glycans on ion
Chemical Tools for Profiling Functioning Ion channel complexes
This project, Prevention Trial of Family Focused Treatment in Youth at Risk for Psychosis, is a multi-site study (UCLA, Yale, Emory, University of North Carolina) testing the efficacy of a family-focused psychosocial intervention in the prevent
PREVENTION TRIAL OF FAMILY FOCUSED TREATMENT IN YOUTH AT RISK FOR PSYCHOSIS
Selective serotonin reuptake inhibitors (SSRIs) have become the mainstream therapy in psychiatric diseases. Based on their therapeutic effect in adults, they are increasingly prescribed in children and adolescents. However, there is a concern a
Molecular mechanisms of SSRI action in childhood and adolescence
) collaboratively with teens, parents, high school teachers, our Information Technology (IT) team, and our research team. The outcome of this modification process will be two interactive web-based high school educational programs. One program w
Reducing Obesity and Diabetes in High Risk Youth
To study the effects of the curcumin derivative drug CNB-001  on  counteracting  the brain  dysfunction after traumatic brain injury (TBI) CNB-001, a potent synthetic derivative of curcumin, has both neuroprotective and neuronal function enhan
Cigarette smoking is a pre-eminent public health problem, recognized as early as 1965. The rapid acquisition and addiction to cigarettes during adolescence is at the root of this continuing epidemic. A cardinal feature of smoking is the high le
Neuron-Specific Candidate Gene Expression and Adolescent Vulnerability to Smoking
The study will provide a significant complement to the parent HCHS/SOL study, to help achieve the goal of examining varied risk and protective factors in Hispanic health and will provide much needed information on the role of SES, sociocultural
ARRA: Ancillary to HCHS/SOL: Sociocultural Factors and CVD Risk/Prevalence in Hispanics
We will apply whole exome sequencing to discover mutations causing structural brain disease in a large cohort of patients from consanguineous union. Comprehensive discovery of mutations that cause brain malformations holds great promise for adv
Gene Discorvery in recessive strutural brain disorders thruogh whole Exome sequencing
ARRA- Scholarships For Disadvantaged Students
American Recovery and Reinvestment Act (ARRA) Supplemental Funding for Reaching More Children and Adults - These ARRA funds will be used to enhance provider enrollment in VacTrAK, Alaska's immunization information system. Funding will support c
American Recovery and Reinvestment Act (ARRA) Supplemental Funding for Reaching More Children and Adults
Administration of Public Health Programs
HEALTH AND HUMAN SERVICES, NEBRASKA DEPARTMENT OF
Develop and implement planned activities as submitted in the grant application to address workforce development for the National Health Service Corps and the Safety Net/Health Center Network.  The activites for the ARRA grant were adjusted begi
Funding to support the State Primary Care Office's:  increased outreach and technical assistance to help clinic sites, health professionals and students apply for student loan repayment and scholarship assistance from the National Health Servic
Town of Wausau Water System Improvement and Extension
195,250 grant, 41,000 loan to purchase fire truck, loan was not required and has been dropped from project.
U.S. Fish and Wildlife Service - Quilcene National Fish Hatchery - Hatchery Seismic & Safety Upgrade
Abernathy Earthen Basin Repair - AE Planning & Design Services
Comprehensive Energy & Water Evaluation Study - U.S. Fish and Wildlife Service, Region Eight.  This study includes evaluations for multiple complexes within the states of California, and Nevada.
Repair water control structures at the Kern County National Wildlife Refuge.
The Turnbull NWR located in northeastern Washington State has several exiting buildings that due to rising energy costs, limited operating budgets, and a variety of Federal energy reduction mandates necessitate that the service renovate the e
LEECH LAKE RESERVATION BUSINESS COMMITTEE INC
The Tribe will construct Life Safety, Handicap Accessibility, and Facility Repairs at three (3) Health Facilities located on the Leech Lake Indian Reservation, with priority to projects in respective order.
MANCHESTER; INSTALLATION OF A TRAFFIC CONTROL SIGNAL @ INTERSECTION OF SLATER STREET AT CIRCUIT CITY/BEST BUY DRIVEWAYS. (CN)
Electrocardiograph with spirometer and cart quantity two (2)
Medical, Dental, and Hospital Equipment and Supplies Merchant Wholesalers
Campus Dr/26th Ave Mill and Overlay from CR 61 to Teakwood Lane, Reconstruction from Teakwood Lane to Sycamore Lane Replace Culvert
ENTERPRISE FOR PROGRESS IN THE COMMUNITY
This award provides for Head Start ARRA Cost of Living Adjustment (COLA) Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start and Early Head Start program.  Head Start promotes
COMMUNITY & TECHNICAL COLLEGES, WASHINGTION STATE BOARD FOR
ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act. Funds will be used to: Hire one full-time (FT) professional development specialist; hire one child
Head Start/Early Head Start 2009 ARRA COLA Quality Improvement Funding
PUGET SOUND EDUCATIONAL SERVICE DISTRICT
Puget Sound ESD received this grant to enhance staff salaries and program support at its 35 sites in King and Pierce Counties for Head Start and Early Head Start comprehensive child development services.  The federal Head Start program promotes
This award funds ARRA Early Head Start Expansion to serve 72 children in Washington State Migrant Council centers located at Othello, Pasco, Wapato, Quincy, College Place and Royal City.  The Early Head Start program provides family-centered se
COMMUNITY CHILD CARE CENTER HANSEN HOUSE
OKANOGAN COUNTY CHILD DEVELOPMENT ASSOCIATION
ARRA COLA & Quality Improvement funds used to provide wage and fringe increase for employees. Utilized part of the funding to increase the professional development of staff and the purchase of a bus
This award provides provides for ARRA Head Start Expansion funded to serve 34 children in two new classroom settings. The Head Start program promotes the school readiness of low-income children throuth the provision of comprehensive health, dev
HEAD START ARRA EXPANSION. This action provides ARRA Head Start expansion funding to support 17 children; of which all 17 are center based in Twin Falls County, Idaho.  This award has allowed College of Southern Idaho Head Start to expand our E
Comm/Pack chicken, Fozen Whole Bagged 36-43 lb ctn; delivery of 39,600# between 6/16 - 6/30.
Mokio Coastal Strand Restoration on Molokai
CMC 1249 - From 9 & 18 Miles South of Noonan, N
National Park Service  Colonial National Historical Park Reconstruct Glasshouse Parking Lot, NOL Trail
Weir Farm National Historic Site - Rehabilitation of Caretaker's Garage into Artist-in-residence Studio Phase II
RENVILLE COUNTY HOUSING AND REDEVELOPMENT AUTHORITY AND ECONOMIC DEVELOPMENT AUTHORITY
This project is a Rural Business Enterprise Grant Revolving Loan Fund to provide financing to eligible businesses in Renville county.  The county is providing financing to small and emerging businesses in the Renville County area that will save
This project is Rural Business Enterprise Grant, Revolving Loan Fund to assist financing for local businesses in Renville County area that will save and/or create jobs.
IMPROVEMENT OF THE QUALITY OF WATER AT THE DIVERSION OF THE EMERY CANAL BY DESIGNING AND CONSTRUCTING A SERIES OF SEDIMENT BASINS WHICH WILL LEAVE THE SEDIMENT IN THE NATURAL STREAM AND CLEAN THE WATER FLOWING TO THE COMMUNITY OF EMERY AND THE
American Recovery and Reinvesment Act Port Security Grant Program (ARRA PAGA)
American Recovery and Reinvestment Act Port Security Grant Program (PGSP)
Security Systems Services (except Locksmiths)
Through the American Recovery and Reinvestment Act Port Security Grant Program (ARRA PSGP), the Marine Division of the New York City Fire Department will enhance its fleet by procuring three boats with shallow draft capabilities for effective e
Port Security Grant Program - Fireboat Purchase and Technology Upgrade
American Recovery and Reinvestment Act, Port Security Grant Program (ARRA_PSGP) 0396
Construct a Maritime domain awareness control center and install perimeter intrusion detection and a TWIC compliant access control system
American Recovery and Reimvestment Act Port Security Grant Program
WOODS HOLE, MARTHA'S VINEYARD AND NANTUCKET STEAMSHIP AUTHORITY
American Recovery and Investment Act Port Security Grant Program (ARRA PSGP)
American Recovery and Reinvestment Act Rail and Transit Security Grant Program-Law Enforcement.
American Recovery and Reinvestment Act Rail and Transit Security Grant Program-Law Enforcement
American Recovery and Reinvestment Act Transit Security Grant Program-Law Enforcement
American Recovery and Reinvestment Act Transit Security Grant Program Capital Projects (ARRA TSGP-CP)
COPS Hiring Recovery Program (CHRP) provides funding directly to law enforcement agencies to hire and/or rehire career law enforcment officers in an effort to create and preserve jobs, and to increase their community policing capacity and crime
The COPS Hiring Program (CHRP) provides funding directly to law enforcement agencies to hire and/ or rehire career law enforcement officers in an effort to create and preserve jobs, and to increase their community policing capacity and crime pr
COPS Hiring Recovery Program (CHRP)for local law enforcement to hire and/or rehire officers to increase communtiy policing capacity.
The COPs Hiring Recovery Program (CHRP provides funding directly to law enforcement agencies to hire and/or rehire career law enforcement officers in an effort to create and preserve jobs, and to increase their community policing capacity and c
The COPS Hiring Recovery Program (CHRP) provided the City of Cincinnati funds to rehire fifty (50) career law enforcement officers in an effort to create and preserve jobs, and to increase community policing capacity and crime prevention effort
COPS Hiring Recovery Program (CHRP) - Public Safety Partnership & Community Policing Grants
THE COPS HIRING RECOVERY PROGRAM (CHRP) PROVIDES FUNDING DIRECTLY TO LAW ENFORCEMENT AGENCIES TO  HIRE AND/OR REHIRE CAREER LAW ENFORCEMENT OFFICERS IN AN EFFORT TO CREATE AND PRESERVE JOBS, AND TO INCREASE THEIR COMMUNITY POLICING CAPACITY AND
The COPS Hiring Recovery Program (CHRP) provides funding directly to law enforcement agency's to hire and/or rehire career law enforcement officers in an effort to create and preserve jobs, and to increase their community policing capacityi and
SALT RIVER PIMA-MARICOPA INDIAN COMMUNITY SOCIAL SERVICE, TH
The COPS Hiring and Recovery Programt (CHRP) provides funding directly to law enforcement agencies to hire and/or rehire career law enforcement officers in an effort to create and preserve jobs, and to increase their community policing capacity
The COPS Hiring Recovery Program (CHRP) provides funding directly to law enforcement agencies to hire and/or rehire career law enorcement officers in an effort to create and preserve jobs, and to increase their community policing capacity and c
HOPLAND BAND OF POMO INDIANS COPS HIRING RECOVERY PROGRAM
The COPS Hiring Recovery Program (CHRP) provides funding directly to law enforcement agencies to hire and/or rehire career law enforcement officers in an effort to crreate and preserve jobs, and to increase their community police capacity and c
The COPS Hiring Recovery Program (CHRP) provides funding directly to law enforcement agencys to hire and/or rehire career law enforcement officers in an effort to create and preserve jobs, and to increase their community policing capacity and c
The COPS Hiring Recovery Program (CHRP) provides funding directly to law enforcementagencies to hire and/or rehire career law enforcement officers in an effort to create and preserve jobs, an to increase their community poplicing capacity and c
The COPS Hiring Recovery Program provides funding directly to law enforcement agencies to hire and/or rehire career law enforcement officers in an effort to create and preserve jobs and to increase their community policing capacity and crime pr
The COPS Recovery Program (CHRP) providing funding directly to enforcement agencies and /or rehire career
The COPS Hiring Recovery Program (CHRP) provides funding directly to law enforcement agencies to hire and/or rehire creer law enformcement officers in an effort to create and proserve jobs, and to increase their commnity policing capacity and c
The COPS Hiring Recovery Program (CHRP) provides funding directly to law enforcement agencies to hire and/ or rehire career law enforcement officers in an effort to create and preserve jobs, and to increase their community policing capacity and
Office of Special Education and Rehabilitative Services
SOUTHWEST CENTER FOR INDEPENDENT LIVING INC
MAXWELL ROAD RELOCATION, TOWN OF COLONIE, ALBANY COUNTY
BIN 3302770, CR83 (HASELTON RD) OVER W BRANCH AUSABLE RIVER
BIN 2200390, BRIDGE AVE BRIDGE OVER MOHAWK RIVER, BR REPLACE
19TH ST, CITY LINE TO CONGRESS ST BRIDGE, RECONSTRUCTION
1R - CR34 (GLENWOOD AVE) RESURFACING PROJECT, WARREN COUNTY
Under Secretary for Health / Veterans Health Administration
Award for construction of state extended care facilities.
Roof Replacement at the Indiana Veterans' Home
SR 951 AT BRIDGE NO. 030148 MARCO ISLAND BRIDGE
Bismarck - South Washington Street from Bismarck Expressway to 175' south of Billings Drive
Mandan - 14th St NE from Collins Ave to 3rd Avenue NE
Consistent with the federal legislative intent, the University of Puerto Rico Graduate School of Public Health (UPR?GSPH) proposes to increase the recruitment and enrollment of the best qualified students in the shortage areas of epidemiology,
ARRA - PUBLIC HEALTH TRAINEESHIP PROGRAM
The proposed project will provide the necessary office and training space to support the expansion of The Jackson Laboratory?s Bioinformatics Biology programs and increase the group?s ability to carry out the collaborations and informal interac
Majority of CIP funds are dedicated to purchase/implementation of a new practice management and EMR system; remaining funds will be used for new paint and flooring for the health center sites.
The Capital Improvement Grant allows ECFH to upgrade old technology as well as remodel a wing in one of our clinics to house behavioral health services.   The technology upgrade is critical as we move to implementing electronic medical records.
CENTRAL CITY COMMUNITY HEALTH CENTER, INC.
Capital Improvement Program through HRSA for alteration and renovation of our existing clinics.  This renovation includes adding additional exam rooms and the necessary equipment to our clinics in order to increase our capacity to improve and i
To construct new facilities to move the current operations of the Yabucoa clinic delivery site. The additional space and design layout will improve COSSMA's effectiveness in maintaining and improving the excellent quality of care provided at th
In an e-mail dated June 25, 2009, we received a Notice of Grant Award for an ARRA Capital Improvement Program grant application for $784,100. The budget for that application is comprised of the following projects and items: ?	$320,00 was budget
MIGRANT HEALTH CENTER, WESTERN REGION, INC
ARRA-Capital Improvement Program:  The purpose of these funds is to construct and remodel our clinic sites at the municipality of San Sebastian, Lajas and Isabela.  With these projects, we expect to increase patients and encounters.  Also, prov
COMMUNITY HEALTH CENTER OF FRANKLIN COUNTY
Project Title: ARRA Capital Improvement Program, Award 01-Renovation and equipping of a new site in Greenfield MA 01301. Approval from DPH for the architect plans was received on July 5, 2011. Construction commenced during July and by the end o
Renovate and equipping of a new site in Greenfield MA 01301
The Delaware Dept. of Education received funds through the American Recovery and Reinvestment Act of 2009 ARRA to assist in the purchase of equipment for School Food Authorities (SFAs) participating in the National School Lunch Program (NSLP) t
Tuberculosis (TB) is a global health problem and it is one of the leading causes of death due to an infectious disease. Increases in drug-resistant TB could reverse the declining trend of TB disease and death. We want to developnew approaches a
Transmission and Virulence of Mycobacterium Tuberculosis
Disease-causing pathogens are among the most intriguing forces shaping human evolution, as they have a tremendous impact on our genome and themselves evolve over time.  A genome-wide survey of human variation indentified two genes biologically
Host and Pathogen Evolution in Lassa Fever
Alzheimer's Disease (AD) is the leading cause of late-onset dementia and is characterized by progressive cognitive decline and memory loss, ultimately leading to death. Over 5 million Americans are currently suffering from AD, and the total cos
EFFECT OF PHYSIOLOGICAL CHANGES IN NEURONAL ACTIVITY AB LEVELS IN VIVO
Indiviudual Fellowship Award to study the following:  In most cases, proteins adopt a single three-dimensional fold that specifies their functions in vivo. There are several protein quality control pathways that help to ensure that proteins ado
INVESTIGATING THE MECHANISM OF SUP35 PRION CURING BY EXCESS HSP104
While strides have been made to reduce the lethality of septic shock, it is still a highly fatal condition that is on the rise. Immunomodulation may prove to be a viable treatment option for sepsis. Immunomodulation consists of the induction of
MECHANISMS OF MONOPHOSPORYL LIPID A IMMUNO-MODULATION IN SEPTIC SHOCK
The goal of the project is to train the applicant in neuroAIDS research as a predoctoral student by studying the role that HIV plays in Causing HIV-associated neurocognitive problems. Dr. Shiramizu will be the mentor for Melissa Agsalda.
HIV DNA in CNS Compartments in Relation to HIV-Associated Neurocognitive Disorders
Caveolin-1, an integral membrane protein highly localized to lipid rafts, has been shown to cause marked decrease in HIV-1 protein expression. Caveolae, the plasmalemmal invaginations formed by caveolin oligomerization, are involved in regulati
Caveolin-1 and negative modulation of HIV-1 replication
DESCRIPTION (provided by applicant):  Addiction to drugs of abuse is an incredible burden to society - costing billions of dollars annually. While it has been long recognized that addiction is a brain disease, the etiology of addiction remains
Prefrontal cortex Homer2, glutamate, and cocaine reward
Declines in episodic memory that accompany normal aging are a growing concern for public health as the average lifespan continues to increase. The hippocampus is a critical structure for long-term episodic and semantic memories and receives maj
AGE EFFECTS ON GRID CELL AND SCENE RECOGNITION SYSTEMS OF ENTORHINAL CORTEX
The parasitic protozoan, Trypanosoma brucei, is the causative agent of sleeping sickness in humans and nagana in domestic livestock. Sleeping sickness is invariably fatal if left untreated. Current drugs are ineffective and toxic, and drug resi
ARRA: Fellowship for John Fisk: Role of the guide RNA binding protein RBP16 in the bloodstream form of T. brucei
Infection by pandemic strains of influenza A virus, as well as the currently circulating H5N1 avian strains, results in a high rate of lethality, primarily due to the excessive accumulation of proinflammatory cytokines/chemokines that precedes
ROLE OF DENDRITIC CELLS IN LETHAL H5N1 INFLUENZA INFECTION
FELLOW:WEST, JOHN-KSHV Modulation of the Host Innate Immune System  The goal of this project is to determine how the immune system detects KSHV and the signaling pathways that are induced by the Toll-like receptors in response to KSHV infection
FELLOW:WEST, JOHN-KSHV Modulation of the Host Innate Immune System
Giardiasis is an important cause of waterborne illness resulting from a one-celled microscopic parasite, Giardia intestinalis (also known as Giardia lamblia). The pathogenic cyst form is protected by an outer shell and can survive outside the b
Investigation of Giardiasis Using Click Chemistry Techniques
Vitamin D3, Autoimmunity and N-Glycosylation: Under the proposed intensive training plan, I will acquire the invaluable scientific skills and knowledge required to achieve a productive, independent scientific career.  The Kirschstein-NRSA Indiv
Vitamin D3, Autoimmunity and N-Glycosylation
Eosinophils have long been thought to function exclusively as 'end stage effector' cells in asthma and other eosinophilic lung disorders, acting through the release of cytotoxic substances. However, mounting evidence has demonstrated that eosin
TETRASPANINS IN ASTHMA AND EOSINOPHILIC LUNG DISEASE
TRUSTEES OF THE UNVERSITY OF PENNSYLVANIA
All viruses tightly regulate cellular processes to create an environment supportive for replication. An understanding of the mechanisms viruses use to do this is vital for our knowledge of viral pathogenesis as well as the normal cellular contr
GENERATION AND CONTROL OF OXIDATIVE STRESS DURING HUMAN CYTOMEGALOVIRUS INFECTION
Shigella is a family of gram-negative bacteria that cause severe infections of the colonic epithelium, leading to an estimated 1.1 million deaths annually. After bacterial entry into host cells, the assembly of host actin into an actin tail at
Conserved Effectors Required for Protein Localization and Shigella Virulence
Cholera, which is caused by ingestion of the Gram-negative pathogen Vibrio cholerae, persists worldwide and affects many thousands of people each year, most of whom do not have access to clean water and sanitary conditions. This disease, charac
Discovery of Vibrio cholerae factors contributing to virulence in Drosophila
Mycobacterium tuberculosis (Mtb) is the leading cause of pathogenic infectious disease mortality worldwide. Roughly one-third of the world’s population is infected with Mtb and nearly two million people die from this disease per year. Thus, t
Investigation of tuberculosis adenylating enzymes using activity probes
DESCRIPTION (provided by applicant): Intracellular pathogens exploit a variety of host factors enabling them to proliferate and cause an array of infections. Listeria monocytogenes is an intracellular pathogen that is able to escape the bacteri
Chloride transport facilitates Listeria monocytogenes vacuole escape
Ebola virus (EBOV) infection of humans often results in severe hemorrhagic fever which is lethal in up to 90% of infected cases. Therefore, understanding the molecular mechanisms of Ebola virus pathogenesis is essential for development of succe
EBOLA VIRUS VP24 ALTERS HNRNP C NUCLEAR IMPORT: IMPLICATIONS FOR REPLICATION
Laboratory Animal Resource Improvements- Utah State University The Laboratory Animal Research Center (LARC) is the only facility on the Utah State University (USU) campus available for the housing and care of laboratory animals. The objective o
LABORATORY ANIMAL RESOURCE IMPROVEMENTS- USU
The Center for Comparative Medicine (CCM) supports the research, teaching and testing activities of Northwestern University (NU) faculty using animals. CCM provides the care for and oversees the humane use of animals, houses research animals, m
Containment Equipment Improvements for Northwestern University
The goal of this project is to maximize investigator utilization of a newly created Comprehensive Facility for Animal Imaging Research (CFAIR) of the Research Imaging Center (RIC) at the University of Texas Health Science Center at San Antonio
MCDERMOTT VIVARIUM RENOVATION TO PROVIDE ADVANCED ANIMAL IMAGING
To remove our existing non-functional bottle washer and old poorly functioning Basil Rack washer; upgrade cage wash supplying electrical, steam and exhaust systems so as to accommodate a new Large Walk-in sterilizer and Tunnel Washer.  After up
NJ Medical School Request for Autoclave and Tunnel Washer
facilities used in highly interactive PHS funded experiments. Our specific aims are to 1) expand mouse housing capacity at the centrally located MTF facility, 2) improve the health of mice by improving the primary housing environment and minim
UCSD MOUSE RESEARCH FACILITIES IMPROVEMENT PROGRAM-MEDICAL TEACHING FACILITY
COMMUNITY HEALTH CARE ASSOCIATION OF NEW YORK STATE, INC.
The Community Health Care Association of New York State (CHCANYS), New York’s 38-year old Primary Care Association and home to the New York Health Choice Network (NYHCN), our statewide Health Center Controlled Network (HCCN), requests continu
EL RIO SANTA CRUZ NEIGHBORHOOD HEALTH CENTER, INC.
ARRA HEalth Information Technology Quality Improvement Grant.  The I2I software being used to track patients and create lists of patients to actively manage the care of the entire CHC entreprise.  This is our FINAL report.  We have satisfied al
Grant Name:  Alabama ARRA State Loan Repayment Program  Purpose:  The purpose of the Alabama ARRA State Loan Repayment Program is to improve access to underserved communities and address primary health care professional shortages that cause dis
because they were uninsured.  The population served has significant health problems, including high rates of cancer, asthma, and hypertension. There are no FQHCs serving the NCNC counties, few physicians in the area and still fewer who accept
North Central Nursing Centers: Caring for Rural Underserved Populations
Of the $1,300,000 for a two-year project period beginning March 1, 2009, based on the budgets included for Year 1 and Year 2.  Of this total, $650,000 is for Year 1, and includes $150,000 for one-time activities and $500,000 is to support ope
With enthusiastic support and by invitation from the Wichita Falls Housing Authority, CHC operates a clinic in the heart of the public housing community offering primary care and preventive service support .  In partnership with the Housing Aut
Recovery Act Health Center Cluster program
ARRA - Increased services to Health Centers is being used by the Holyoke Health Center to increase access to primary care by hiring additional medical and support staff to provide appropriate primary care and women's health services.
Northwest Health Services has set a goal to hire a bi-lingual provider in order to meet the needs of the recent influx of Spanish speaking workers from the Triumph Foods pork plant, as well as reach out to the chronically uninsured population a
ARRA - INCREASE SERVICES TO HEALTH CENTERS
ARRA - Increase Services to Health Center in response to an Increased Demand For Services (IDS).  This award enables the applicant to maintain services while enhancing capacity, retain primary care provider staff and ensure quality care standar
LEWIS COUNTY COMMUNITY HEALTH SERVICES INC
The American Recovery and Reinvestment Act provided funding to Increase Services to Health Centers. This allowed Valley View Health Center to retain positions; which would otherwise be lost due to budget constraints, to create new positions, an
The FHCB IDS project will be responsive to the health care needs of patients, culturally competent and Joint Commission compliant.  The project will be implemented at the large practices - downtown and Cherry Hill.  Missed appointments will be
The award description is Increased Demand for Services (IDS). One full time equivalent internal medicine physician was retained. The goal was to see 160 new patients during the period of the award of which 117 would be uninsured.For the two yea
The purpose of this award is to expand primary care services for homeless persons with the addition of a 1.0 FTE Advanced Registered Nurse Practitioner (ARNP) and a 1.0 FTE Medical Assistant (MA). The expansion will alleviate increasing delays
IDS  funds support STEEMCC's activities to enhance case management services and assure increased access to primary, preventive care for the target population with a special focus on the pediatric and adult high risk population.
VETERANS MEDICAL RESEARCH FOUNDATION OF SAN DIEGO
The impact of antiretroviral therapy represents a major demonstration of the capability and success of modern drug discovery, development, and implementation. Nevertheless, in infected individuals this success lasts only as long as adherence to
Targeting regulators of cellular gene transcription to impact HIV latency
The key to understanding the results of the STEP/Phambili trials is first to model the results of the trial in controlled experiments using mucosal SIV inoculation of rhesus macaques.  Thus, we will determine the effectiveness and potential of
Mechanims of Protection From, and Enhanced Susceptibility to, HIV Infection Afte
The University of Rochester hosts a vibrant, interdisciplinary team of scientists working on projects at the intersection of metabolic regulation and aging. We have identified several areas of competence that would strategically strengthen this
FACULTY RECRUITMENT IN AGING AND METABOLISM RESEARCH
This grant mechanism is designed to support the hiring of a newly-recruited faculty member and to develop research projects within the context of Biomedical Core Centers.  The award is designed to enhance innovative programs of excellence by pr
MUSCLE TRIGLYCERIDE METABOLISM CORE CENTER
This award provides for the recruitment of a scientist dedicated to the basic and translational research of angiogenesis and  tumor microenvironment proposed in this application supports three of the scientific priorities of the  entities: 1) t
The P30 award will provide critical support for strengthening two of the Cancer Center's seven multidisciplinary research programs. Two candidates are proposed for recruitment-one into the Viral Oncology Program and the other into the Bio-behav
ENHANCEMENT OF TWO KEY RESEARCH PROGRAMS WITHIN THE SYLVESTER CANCER CENTER
Contingency management (CM) interventions are efficacious in improving outcomes of substance abusing patients. With the increasing evidence basis of CM, providers are expressing interest in learning about CM implementation. Currently, no centra
RECOVERY ENHANCEMENT WITH AWARDS ENHANCEMENT WITH AWARDS RESEARCH DISSEMINATION
THE COPS HIRING RECOVERY PROGRAM (CHRP) PROVIDES FUDNING DIRECTLY TO LAW ENFORCEMENT AGENCIES TO HIRE AND/OR REHIRE CAREER LAW ENFORCEMENT OFFICERS IN AN EFFORT TO CREATE AND PRESERVE JOBS, AND TO INCREASE THEIR COMMUNITY POLICING CAPACTIY AND
CHRP provides funding directly to law enforcement agencies to hire and/or rehire career law enforcement officers in an effort to create and preserve jobs,and to increase their community policing capacity and crime prevention efforts,
The COPS Hiring Recovery Program (CHRP) provides funding directly to the law enforcement agencies to hire and/or rehire law enforcement officers in an effort to create and preserve jobs, and to increase their community policing capacity and cri
The COPS Hiring Recovery Program (CHRP) provides funding directly to law enforcement agencies to hir and / or rehire career law enforcement officers.
The COPS Hiring Recovery Program (CHRP) provides funding directly to law enforcement agencies to hire and/or rehire career law enforcement officers in an effort to create and preserve jobs, and to increase their community policing capability an
The COPS Hiring Recovery Prgram (CHRP) provides funding directly to law enforcement agencies to hire and/or rehire career law enforcement officers in an effort to create and preserve jobs.
The COPS Hiring Recovery Program(CHRP) provided funding directly to law enforcement agencies to hire and/or rehire career law enforcment officers in an effort to create and preserve jobs, and to increase their community policing capacity and cr
The COPS hiring recovery program provides funding directly to law enforcement agencies to hire and or rehire career law enforcement officers in an effort to create and preserve jobs and to increase their community policing capacity and crime pr
'The COPS Hiring Recovery Program(CHRP) provides the funding directly to law enforcement officers in an effort to create and preserve jobs, and to increase their community policing capacity and crime prevention efforts'
COPS Hiring Recovery Program for Fort Belknap Fish & Wildlife. To provide funding directly to our Fish and Wildlife Department to hire an officer to create jobs and increase our community policing capacity and crime prevention efforts.
THE COPS HIRING RECOVERY PROGRAM PROVIDES FUNDING DIRECTLY TO LAW ENFORCEMENT AGENCIES TO HIRE AND/OR REHIRE CAREER LAW ENFORCEMENT OFFICERS IN AN EFFORT TO CREATE AND PRESERVE JOBS,AND TO INCREASE THEIR COMMUNITY POLICING CAPACITY AND CRIME PR
The COPS Hiring Recovery (CHRP) provides funding directly to law enforcement agencies to hire and/or rehire career law enforcement officers in an effort to create and preserve jobs, and to increase their community policing capacity and crime pr
THE COPS HIRING RECOVERY PROGRAM PROVIDES FUNDING DIRECTLY TO LAW ENFORCEMENT AGENCIES TO HIRE OR REHIRE OFFICERS IN AN EFFORT TO CREATE OR PRESERVE JOBS AND TO INCREASE THEIR COMMUNITY POLICING CAPACITIES AND CRIME PREVENTION EFFORTS.
The COPS Hiring Recovery Program (CHRP)provides funding directly to law enforcement agency's to hire and/or rehire career law enforcement officers in an effort to create and preserve jobs, and to increase their community policing capacity and c
The COPS Hiring Recovery Program (CHRP) provides funding directly to law enforcement agencies to hire and/or rehire career law enforcement officers in an effort to create and preserve jobs,  and to increase their community policing capacity and
The COPS Hiring Recovery Program (CHRP) provides funding directly to law enforcement agencies to hire and/or rehire law enforcement officers in an effort to create and preserve jobs, and to increase their community policing capacity and crime p
The Cops Hiring Recovery Program CHRP provides funding directly to law enforcement agencies to hire and/or rehire career law enforcement officers in an effort to create and preserve jobs, and to increase their community policing capacity and cr
The COPS Hiring Recovery Program (CHRP) provides funding directly to law enforcement agencies to hire and or rehire career law enforcement officers in an effort to create and preserve jobs and to increase their community policing capacity and c
'The COPS Hiring Recovery Program provides funding directly to law enforcement agencies to hire and/ or rehire career law enforcement officers in an effort to create and preserve jobs, and to increase their community policing capacity and crime
The Cops Hiring Recovery Program (CHRP) provides funding directly to law enforcement agencies to hire and/or rehire career law enforcement officers in an effort to create and preserve jobs, and to increase their community policing capacity and
The Cops Hiring Recovery Program (CHRP) provides funding directly to law enforcement agencies to hire and/or rehire career law enforcement officers in an effort to create and preserve jobs and to increase their community policing capacity and c
The Cops Hiring Recovery Program(CHRP) provides funding directly to law enforcemnt agencies to hire and/or rehire career law enforcement officersw in an effort to create and preserve jobs, and to increase their community policing capacity and c
The COPS Hiring Recovery Program (CHRP) provides finding directly to law enforcement agencies to hire and / or rehire career law enforcement officer in an effort to create and preserve jobs, and to increase their community policing capacity and
'The COPS Hiring Recovery Program (CHRP) provides funding directly to law enforcement officers in an effort to create and preserve jobs, and to increase their community policing capacity and crime prevention efforts.'
'The COPS Hiring Recovery Program (CHRP) provides funding directly to law enforcement agencies to hire and/or rehire career law enforcement officers in an effort to create and preserve jobs, and to increase their community policing capability a
COPS Hiring Recovery Program provides funding directly to law enforcement agencies to hire and/or rehire career law enforcement officers in an effort to create and preserve jobs, and to increase their community policing capacity and crime preve
The COPS Hiring Recovery Program (CHRP) provides funding directly to law enforcement agencies to hire and/or rehire career law enforcement officers in an affort to create and preserve jobs, and to increase their community policing capacity and
The COPS Hiring and Recovery Program (CHRP) provides funding directly to law enforcement agencies to hire and/or rehire career law enforcement officers in an effort to create and preserve jobs, and to increase their community policing capacity
COPS grant to fund law enforcement officers to create and preserve jobs and increase community policing capacity and crime prevention efforts.
The COPS Hiring Recovery Program 'CHRP' provides funding directly to law enforcement agencies to hire and/or rehire career law enforcement officers in an effort to create and preserve jobs, and to increase their community policing capacity and
The COPS Hiring Recovery Program (CHRP) provides funding to law enforcement agencies to hire and/or rehire career law enforcement officers.  The Hopewell Police Department was awarded 3 CHRP positions in July 2009.
THE COPS HIRING RECOVERY PROGRAM (CHRP) PROVIDES FUNDING DIRECTLY TO LAW ENFORCEMENT AGENCIES TO HIRE AND/ OR REHIRE CAREER LAW ENFORCEMENT OFFICERS IN AN EFFORT TO CREARE AND PRESERVE JOBS, AND TO INCREASE THEIR COMMUNITY POLICING CAPACITY AND
The COPS Hiring Recovery Program (CHRP)provides funding directly to law enforcement agencies to hire and/or rehire career law enforcement officers in an effort to create and preserve jobs, and to increase their community policing capacity and c
The COPS hiring Recovery Program (CHRP) provides funding directly to law enforcement agencies to hire or re-hire law enforcement officers in an effort to create and preserve jobs and to increase our community policing and crime prevention capac
The COPS Hiring Recovery Program (CHRP) provides funding directly to law enforcement agencies to hire and/or rehaire career law enforcement officers in an effort to create and preserve jobs, and to increase their community policing capacity and
The COPS Hiring Recovery Program (CHRP) prOvides funding directly to law enforcement agencies to hire and/or rehire career law enforcement officers in an effort to create and preserve jobs and to increase their community policing capacity and c
The COP Hiring Recovery Program (CHRP) provides funding directly to Law Enforcement agencies to hire and/or rehire career law enforcement officers in an effort to create and preserve jobs, and to increase their community policing capicity and c
COPS Hiring Recovery Program (CHRP)that provides funding directly to law enforcement agencies having primary law enforcement authority to create and preserve jobs and to increase their community policing capacity and crime-prevention efforts.
The COPS Hiring Recover Program (CHRP) provides funding directly to law enforcement agencies to hire and/or rehire career law enforcement officers in an effort to create and preserve jobs, and to increase their community policing capacity and c
Narrative as requested by OJP:  Franklin County was selected by the disparate jurisdictions to serve as the fiscal agent, and the group agreed to the following Recovery Act JAG allocations:  Franklin County $2,439,588, Columbus $1,770,000; Bexl
Recovery Act Justice Assistance Grant Program
The primary goal of this project was to maximize job retention at the Revere Police Department and retain three officer positions. The Bureau of Justice Assistance, Edward Byrne Memorial Recovery Justice Assistance Grant was to fund the three o
To prepare high school students for careers in the Criminal Justice System by continuing to promote the Criminal Justice Program to said students.  Assist crime victims in their contact with the criminal justice system by continuing to be respo
Criminal Justice, Law Enforcement and Circuit Court Programs
Initiative to Enhance Services to Child Victims and Delinquent or Unruly Children
JAG funds support all components of the criminal justice system, from multijurisdictional drug and gang task forces to crime prevention and domestic violence programs, courts, corrections, treatment, and justice information sharing initiatives.
Multi-jurisdictional Communications Interoperability and Equipment Replacement Program
Law Enforcement Vehicle and Technology Project
To purchase seven mobile data terminals,and purchase eight computers and upgrade their records management system.
Ocean City Police Department & Worcester County Sheriff Department FY2009 Recovery Act JAG Award
Grant funds for the purchase of law enforcement equipment, including an unmarked police vehicle, graffiti enforcement equipment, narcotics detection canine, hostage/crisis negotiation equipment.  Each of these items will be placed into full-tim
Logan Police Recovery Justice Assistance Grant
The Jackson Police Department's goal of this project is to fund the positions of two police officers from July 1, 2009, through June 30, 2010.  The retention of the two positions will aid the department in maintaining its level of service to th
BJA FY 2009 Recovery Act Edward Byrne Memorial Justice Assistance Grant Program Local Solicitation
Purchase of Safety and Investigative Equipment, Investigative Training and retaining a Lieutenant's position
The Farmington Police Department, Wilton Police Department and Franklin County Sheriff's Department Investigative Personnel and Investigative and Safety Equipment Acquisition
BANKS COUNTY SHERIFF'S OFFICE COMMUNICATION UPGRADE AND IMPLEMENTATION.
Support Treatment After Release (STAR) Program
Funding OT for officers particpating in Emergency Tactical Unit training and Police Activities League.
'The COPS Hiring recovery Program (CHRP) provides funding directly to law enforcement agencies to hire and/or rehire career law enforcement officers in an effort to create and preserve jobs, and to increase thier community policing capacity and
The COPS Hiring Recovery Program (CHRP) provides funding directly to law enforcement agencies to hire and/or rehire career law e0nforcement officers in an effort to create and preserve jobs, and to increase their community policing capacity and
The COPS Hiring Recovery Program (CHRP)provides funding directly to law enforcement agency's to hire and/or rehire career law enforcement officers in effort to crate and preserve jobs, and to increase their community policing capacity and crime
The COPS Hiring Recovery Program (CHRP) provides funding directly to law enforcement agencies to hire or rehire career law enforcement officers in an effort to create and preserve jobs and to increase their community policing capacity and crime
The COPS Hiring Recovery Program (CHRP) provides funding directly to law enforcement agencies to hire and/or rehire career law enforcement offficers in an effort to create and preserve jobs, and to increase their community policing capacity and
The COPS Hiring and Recovery act(CHRP) provides funding directly to law enforcement agencies to hire and rehire career Law enforcement officers in an effort to create preserve jobs.
The COPS Hiring Recovery Program (CHRP) is funded through the American Recovery and Reinvestment Act (Recovery Act) and provides funding directly to law enforcement agencies to hire and/or rehire career law enforcement officers in an effort to
The COPS Hiring Recovery Program (CHRP) provides funding directly to law enforcement agency's to hire and/or rehire career law enforcement officers in an effort to create and preserve jobs, and to increase their community policing capacity and
'The COPS Hiring Recovery Program (CHRP) provides funding directly to law enforcement agencies to hire an/or rehire career law enforcement officers in an effort to create and preserve jobs, and to increase their community policing capacity and
The COPS Hiring Recovery Program (CHRP) provides funding directly to law enforcement agencies to hire and/or retain career law enforcement officers in an effort to create and preserve jobs, and to increase their community policing capacity and
The City of Springfield Police Division seeks to hire/retain 7 officers. 6 will be used as School Resource Officers (SRO).  These officers are assigned to the Springfield City High School and the 5 middle schools to assist both administration a
CUYAHOGA METROPLITAN HOUSING AUTHORITY POLICE DEPT
The COPS Hiring Recovery Program (CHRP) provide funding directly to law enforcement officers in an effort to create or preserve jobs, and to increase their community policing capacity and crime prevention efforts.
Three full time law enforcement officers are functioning in the capacity of community/problem solving officers.
COPS Hiring Recovery Program  (CHRP)provides funding directly to law enforcement agencies to hire and/ or rehire career law enforcement officers.
The COPS Hiring Recovery Programs (CHRP) provides funding directly to law enforcement agencies to hire and/or rehire career law enforcement officers in an effort to create and preserve jobs, and to increase thier community policing capacity and
The COPS Hiring Recovery Program (CHRP) For one officer to increase our departments community policing capacity, and crime prevention efforts.
The COPS Hiring Recovery Program (CHRP) provides funding directly to law enforcement agencies to hire and or rehire career law enforcement officers in an effort to create and preserve jobs, and to increase their community policing capacity and
The COPS Hiring Recovery Program(CHRP) provides funding directly to law enforcement agencies to hire and/or rehire career law enforcement officers in an effort to create and preserve jobs, and to increase their community policing capacity and c
The COPS Hiring Recovery Program (CHRP)provides funding directly to law enforcment agencies to hire and/or rehire career law enforcement officers in an effort to create and preserve jobs, and to increase their community policing capacity and cr
Funds to hire police for Nisqually law Enforcement
The COPS Hiring Recovery Program (CHRP) provides funding directly to law enforcement agencies to hire and/or rehire career law enforcement officers in an
Funding for the Hiring of a Full Time Police Officer
The Cops Hiring Recovery Program (CHRP) provides funding directly to law enforcement officers in an effort to create and preserve jobs, and to increase their community policing capacity and crime prevention efforts.
The COPS Hiring Recover Program provides funding directly to law enforcement agencies to hire and/or rehire career law enforcement officers in an effort to create and preserve jobs, and to increase their community policing capacity and crime pr
Anne Arundel Recovery Act JAG - Public Safety Equipment
Hall County, through the Hall County Sheriff?s Office will use Recovery JAG funds in the amount of $128,245 to enhance communication capabilities by purchasing mobile data systems and supporting equipment for patrol vehicles. This project will
Hall County Sheriff Recovery Act: Edward Byrne Memorial Justice Assistance Grant (JAG) Formula Program: Local Solicitation
upgrading equipment for sheriff's deputies, dectives, detention and administration
Lake County Sheriff's Office Equipment and Supply Upgrade
Recovery Act Justice Grant Program.  Grant number 2009-SB-B9-0088 is funding two projects.    1. City of Pendleton Police Department purchased infrastructure and components to create a meshed wireless network, which serves as the platform for m
The purpose of our proposed Recovery Act Funds is to provide the Hamden Police Department with a new Emergency Services Unit that will be utilized to replace the existing vehicle which is approximately 25 years old and in desparate need of repl
Purchase Emergency Services vehicle, & firearms.
Purchase of two Police cars and related equipment.
The Nortwest Regionalized Information System recognizes the need for local communities to combine services where taxpayer money can be saved.  As Erie County and Sandusky City are certified disparate both entities agree that Erie County will be
Reinstate Law Enforcement Officer Positions No Longer Funded In Our Agency's Budget
Law Enforcement Essential Services Recovery program
Laramie City will use this grant for a Mobile data terminal, Albany County For less lethal equipment and in-car video camera
Police Cruiser Replacement Program--grant funds allowed purchase of five (5) new police cars to replace high-mileage cars.
Downtown Resource Officer Grant to partially fund a law enforcement officer assigned to the downtown sector of the city.
Continuation or completion of several ongoing projects:  mobile data terminals in patrol units, lidar (laser radar units), web site development, and tasers.  Also, riot helmets, stop sticks, and radio chargers.
2009 recovery act justice assistance program
FY 09 Recovery Act Edward Byrne Memorial Justice Assistance Grant Program Local Solicitation
Digital In-Car Camera Program/City Holding Facility Video System
To be used for the purchase of two patrol vehicles and equipment.
Over 7,100 citations are issued each year by officers in the Tigard Police Department.  The majority of those citations are issued by the motorcycle officers assigned to the Traffic Safety Unit.  Currently, the officers use a paper-issued syste
Tigard E-Ticketing Initiative and MDC Upgrade
Courtroom and Courthouse Security System
Butler County Sheriff to use its funding of $300,234.00 for salaries as approved in a GAN on 6/28/2010. Budget cut of 1.7 million dollars.  This resulted in 24 layoffs effective July 19, 2010.  Scope of this grant to cover salaries for Deputies
2009 JAG ARRA funds are being used to pay for equipment, personnel, and supplies to enable the Lima Police Department and the Allen County Sheriff's Office to conduct routine policing of Lima, including street violence, drug offenses, vandalism
2009 Recovery Act Edward Byrne Memorial Justice Assistance Grant
Mobile Data System technology upgrade, IT technology infrastructure upgrade.
FY 09 Recovery Act Edward Byrne Memorial Justice Assistance Grant Program - Funding for 2.18 years for a Forensic Computer Examiner
BJA FY 09 Recovery Act Edward Byrne Memorial Justice Assistance Grant Program Local Solicitation
The Marion Police Department has two projects they funded with the grant money. One project will be completed and the second project will be nearly completed with plans to complete the project in the next 1 to 2 years. Project # 1 – Laptop Co
Marion and Grant County Technology and Equipment Acquistion
The Edward Byrne Memorial Justice Assistance Grant (JAG) Program is the primary provider of federal criminal justice funding to state and local jursidictions.  JAG funds support all components of the criminal justice system, from multijurisdict
Providence Police Department's Return to Neighborhoods Initiative
To support the needs of the Bastrop County Sheriff's office by purchasing eleven digital in-car surveillance cameras.
BJA FY09 Recovery Act Edward Byrne Memorial Justice Assistance Grant Program
The City of Canton Police Department intends to use this funding for the purchase of equipment.  This equipment will be used to improve the safety of our officers, our citizenry, and the motorists that travel within our jurisdictional limits.
Canton City FY2009 Recovery Act Justice Assistance Grant Program
FY 09 Recovery Act Edward Byrne Memorial Justice Assistance Grant Program Local Soliciation in the amount of $29,807.00.  Purchase a vehicle to replace another one that has high mileage and high maintenance cost.
Recovery Act Edward Byrne Memorial Justice Assistance Grant Program Local Solicitation
St. Charles County will use the Recovery Act JAG funds to hire a cyber crime records clerk in the County Sheriff's Department.
BJA FY 09 Recovery Act - Edward Byrne Memorial Justice Assistance Grant Program Local Solicitation for Task Force and Communications Center Upgrade
The disparate jurisdictions consisting of Scott County and cities of Bettendorf and Davenport will share the Recovery Act JAG funds. Scott County, serving as the fiscal agent, will provide $300,000 to the city of Davenport to allow them to equi
Macomb County, serving as the fiscal agent for this award, will share the Recovery Act   JAG funds with the cities of Warren, Center Line, Eastpointe, Fraser, Mount Clemens, Richmond, Roseville, St. Clair Shores, Sterling Heights, and the chart
Macomb County Michigan?s Crime Prevention and Control Initiative
The Baldwin County Commission was awarded 69070 to preserve one position (the Victim Service Officer / Trial Coordinator) for Domestic Violence and Juvenile Courts which would have been lost due to state funding cuts. Funds will cover salary, b
Assistance for training and budgetary restraints
Assistance for Taining and Budgeatry Contstraints
TFT TITLE: 16.804 Recovery Act: Edward Byrne Monorial Justice Assistance Grant (JAF) Program/Grant
Police equipment upgrades including vehicles, computers, cameras etc.
FY09 Recovery Act-Edward Bryne Memorial Justice Assistance Grant (JAG)
Equipment upgrade and replacement Program.
Equipment upgrade and replacement Program
FY 2009 Recovery Act Justice Assistance Grant Program.  The Binghamton Police Department intends to supplement the purchase of 102 Soft Body armor vests for police officers, the purchase of 2 police vehicles and to spend $32,697 in overtime to
Orange County and the Cities of Middletown, Newburgh, Port Jervis, The Towns of Newburgh, New Windsor, Wallkill, and the Village of Monroe will use Recovery Act funds in the amount of $406,267 to support initiatives that will enable each jurisd
FY 2009 Recovery Act Justice Assistance Grant Program
Town of Barnstable (Prime Recipient): Community Policing Initiatives targeted toward directed patrols to address key community policing area that affect the quality of life in the Town of Barnstable: drug interdiction.  Also, the purchase of au
The disparate jurisdictions,consisting of Greene County and the cities of Springfield,Republic and Willard will use their Recovery Act JAG award in the amount of $666,180 to acquire and replace law enforcement equipment,support personnel and in
Bureau of Justice Assistance Justice Assistance Recovery Grant funding to be used to purchase 800 MHz radios for implementation of an interoperable radio system.
The Edward Byrne Memorial Justice Assistance Grant (JAG) Program is the primary provider of federal criminal justice funding to state and local jurisdictions. JAG funds support all components of the criminal justice system, from multijurisdicti
The New York City Mayor's Office of the Criminal Justice Coordinator (CJC) serves as the applicant and administrator for the FY09 American Reinvestment and Recovery Act (ARRA) Justice Assistance Grant (JAG) program for the City of New York. In
JAG Recovery program funding will be used to supplement police programs in an effort to decrease overall crime.
FY 2009 Recovery Justice Assistance Grant Program
BJA FY 09 Recovery Act Edward Byrne Memorial Justice Assistance Program Grant - Solicitation - Police Mobile Radios
Mission Police Department Mobile Radio Project
Mt. Pleasant, Texas JAG Assistance Program
FY 09 Recovery Act Justice Assistance Grant Program
Purchase and acquisition of law enforcement equipment and technology.
Purchase and installation of seven police patrol car mounted audio/video camera systems.
FY09 Recovery Act Edward Byrne Memorial Justice Assistance Grant Program
This grant is being used to upgrade our communication system.  We are purchasing equipment to digitally dispatch patrol units to calls for service.  Additionally, we are purchasing a GPS system to track patrol units and send the closest unit to
law enforcement equipment,fy 09 Recovery act
Burleson Texas city recovery act  byrne grant
The City of Parsons and Labette County will use the JAG Recovery Grant to increase public safety and add more detailed security. Parsons will use $32,430 to purchase 6-forward looking infrared, one flash sight, two Pentax D200 cameras, one unde
Advancing Evidence Collection Systems & Addressing Officer Safety Project
Recovery Act: Edward Byrne Memorial Justice Assistance Grant Formula Program: Local Solicitation
The Hinesville Police Department and the Liberty County Sheriff's Department submitted a joint application for varying equipment.
Hinesville/Liberty County Law Enforcement Enhancement
ARRA - Byrne Non-Competitive funding which will be used for implementation of an online tip reporting system, for software upgrades, equipment, a vehicle, and other crime fighting efforts.
ARRA JAG Formula - The City of Portland will fund three specific program areas including gang outreach and intervention, records management replacement technical support and prostitution outreach and intervention services, all which will create
FY09 Justice Assistance Grant Program - ARRA Formula
The disparate jurisdictions consisting of the city of Bainbridge and the county of Decatur will share the Fiscal year 2009 Recovery Act JAG to purchase equipment and technolgy upgrade.
In 2005 the U.S. Congress, at the recommendation of the Department of Defense, decided to close several military installations through the Base Realignment and Closure (BRAC) process. One of the selected sites was Ft. Gillem Army Base located i
FY 09 Recovery Act Edward Byrne Memorial Justice Assistance Grant Program Local
Recovery Act:  Edward Byrne Memorial Justice Assistance Grant Formula Program - Local Solicitation funds awarded City of Plant City, Plant City Police Department for the modernization of police equipment.
Purchase Equipment for the St. Peters Police Department.  This equipment consists of a Firearms Training Simulator, Direction-Sensing Traffic Radar Units, Rechargeable Flash Lights and Holders, and Pedestrian and Traffic Control Signs.
Purchase Equipment for the St. Peters Police Department
The Winthrop Police Department's Recovery Act for Community Policing and Narcotics investigation
The Winthrop Police Department's Recovery Act for Community Policing and Narcotics Investigations
Edward Byrne Memorial Assistance Program
CASE (Caldwell Advanced Surveillance Equipment)
The City of Laredo and Webb County are listed as disparate jurisdictions under the FY 2009 JAG Recovery Local allocation list.  The city will service as the fiscal agent to administer the JAG Recovery funds for both jurisdictions.  Each jurisdi
Claiborne County Sheriff's: OFFICER SAFETY INCENTIVE
City of Montrose and Montrose County COIBRS and Mobile Data Computer Remote Access Project
This grant is authorized by the American Recovery and Reinvestment Act of 2009. The stated purposes of the Recovery Act are: To preserve and create jobs and promote economic recovery; to assist those most impacted by the recession; to provide i
Andalusia Police Department Recovery Act JAG Formula Grant
Doral Incident Command System Project which includes the purchase of a bumperchute, 3 trunk vaults for command staff, and incident command software
'This research will determine how the shifting seasonality of arctic river hydrology alters key biotic linkages within and among lake and stream components of watersheds and may alter the function of the arctic system. Arctic grayling (Thymallu
Collaborative proposal: Shifting seasonality of Arctic river hydology alters key biotic linkages among aquatic systems
This research will determine how the shifting seasonality of arctic river hydrology alters key biotic linkages within and among lake and stream components of watersheds and may alter the function of the arctic system. Arctic grayling (Thymallus
Collaborative Research: Shifting seasonality of Arctic river hydrology alters key biotic linkages among aquatic systems
Collaborative: How the Timing of Summer Precipitation Affects the Responses of Boreal Forest to Climate Change
I-90/Slide Curve to Cabin Creek - Paving
Funding is provided to obtain new ice core accumulation records from Combatant Col, Mt. Waddington, in southwestern British Columbia (BC), Canada. Combatant Col is located significantly farther south than other existing ice core sites along the
Collaborative Research: P2C2--Ice Core Paleoclimate Records from Combatant Col, British Columbia, Canada
Anomalous local turbulent transport in plasmas will be measured directly with novel diagnostics. By measuring critical parameters, the fundamental scaling laws of transport will be compared with various theories. A key element of the project is
Experimental Studies of Basic Physics of Plasma Transport
This project contributes tools to engineer future information processing systems so that they operate reliably and efficiently. Given that many of these systems will be produced on single micro-chips, and given the increasing demands for rapid
COLLABORATIVE - MCDA: FORMAL ANALYSIS OF MULTICORE COMMUNICATION APIS AND APPLICATIONS
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). This is a group project in computational high energy physics being carried out by physicsts at the University of Arizona, University of California
Collaborative Research: Human Resources for Computational High Energy Physics
COLLABORATIVE RESEARCH: HUMAN RESOURCES FOR COMPUTATIONAL HIGH ENERGY PHYSICS
Award Description:  The Clean Energy for Green Industry (Clean-Green) IGERT at the University of California, Los Angeles (UCLA) is designed to train U.S. Ph.D. scientists and engineers for leadership roles in the clean energy sector - universit
IGERT: CLEAN ENERGY FOR GREEN INDUSTRY AT UCLA
The primary focus of this theory program is on pure electron plasmas, in particular the properties of low density electron plasma equilibria. The theories developed are now being tested in several devices, not only on the Columbia Nonneutral To
Physics of non-neutral and electron-position plasmas confined on magnetic surfaces
This research focuses on two frontiers of plasma physics where particle-in-cell (PIC) simulations can help elucidate underlying principles of energy transfer in plasmas: (1) Motivated by collisionless accretion disks, we will study whether a fa
ENERGY TRANSFER IN COLLISIONLESS ASTROPHYSICAL PLASMAS
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). The Community Infrastructure for General Relativistic Magnetohydrodynamics (CIGR) collaboration will create a modern, scalable, and open, communit
ARRA: COLLABORATIVE RESEARCH: COMMUNITY INFRASTRUCTURE FOR GENERAL RELATIVISTIC MHD (CIGR)
Collaborative Proposal: Continuation of th XENON Dark Matter Project: Construction and Underground Operation of an Upgraded XENON100 Detector
The investigators will carry out high spatial resolution mid-infrared imaging, spectroscopy, and polarimetry of nearby active galactic nuclei (AGN), taking advantage of the subarcsecond, diffraction limited resolution afforded by 8-10m telescop
Collaborative Proposal: Resolved Mid-IR Observations & Modeling of AGN and their Hosts
The goal of our interdisciplinary e ort between computational scientists, physicists, engineers and applied mathematicians is to build an all{scales unified simulation system that can exploit the next generation of petascale systems and beyond.
This award supports a research program to develop petascale numerical simulations of structure formation in the universe. This work will utilize the Adaptive Refinement Tree (ART) cosmological simulation code. Specific goals are: (1) to achieve
COLLABORATIVE RESEARCH:  TOWARDS PETASCALE COSMOLOGICAL SIMULATIONS
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).   The investigators, with their students and postdocs, pursue an interdisciplinary project with three primary aims. The first aim is the developme
Collaborative Research: Simulation and Analysis of Turbulent Jet Noise Using Arbitrary-Order Hermite Methods
A recent study by the Agency for Healthcare Research and Quality (AHRQ) documented over 32,000 mostly surgery-related deaths, costing nine billion dollars and accounting for 2.4 million extra days in hospital in 2000. At the same time, economic
III: Medium: A Machine Learning Approach to Computational Understanding of Skill Criteria in Surgical Training
This project will develop an advanced 3-D hybrid simulation code (fluid electrons + kinetic ions) that included the coupling of the  magnetosphere to the ionosphere. The hybrid magnetosphere model will be coupled an ionospheric model developed
(ARRA) Collaborative research: Enabling breakthrough kinetic simulations of the magnetosphere via multi-zone petascale computing
The expression of affect in face-to-face situations requires the ability to generate a complex, coordinated, cross-modal affective signal, having gesture, facial expression, vocal prosody, and language content modalities. This ability is compro
HCC: Medium: Automatic detection of atypical patterns in cross-modal affect
Recently, the concept of ?brain games? that could slow or even reverse cognitive decline has become popular around the world. However, research into these existing games shows little in the way of general cognitive benefits. Research into novel
HCC: Medium: Collaborative Research: Improving Older Adult Cognition: The Unexamined Role of Games and Social Computing Environments
This project is developing computational agents that operate for extended periods of time in rich and dynamic environments, and achieve mastery of many aspects of their environments without task-specific programming. To accomplish these goals,
Medium: Building Flexible, Robust, and Autonomous Agents,
Title: RI: Medium: Collaborative Research: Robotic Hands: Understanding and Implementing Adaptive Grasping. This NSF award is a collaborative research with Columbia University and Arizona State University. This research is aimed at alleviating
TECHNICAL SUMMARY  The objective of this proposal is to understand and model the microstructure and deformation mechanisms controlling the strength and ductility as a function of temperature and strain rate for different lamellar spacings in a
Microstructure and Mechanical Behavior of FeNiMnAl Eutectic Alloys
This project is for the design and construction of a sideband-separating Superconductor-Insulator-Superconductor mixer receiver for the 380 to 500 GHz band. The receiver, whose design will mimic that used for the Atacama Large Millimeter/submil
A Sideband-Separating Receiver at 385-500 GHz: Advancing Spectroscopic Frontiers at Sub-Millimeter Wavelengths
RI:Medium: Collaborative Research: Solving Stochastic Planning Problems Through Principled Determinization
RI: Medium: Collaborative Research: Physically Grounded Object Recognition  Most of today’s approaches to visual object recognition essentially reduce the problem to one of 2D pattern classification, where rectangular image patches are indepe
RI: Medium: Collaborative Research: Physically Grounded Object Recognition
The nature of telecommunications networks is rapidly changing. Commodity smart mobile phone frameworks such as Android and Openmoko invite developers and end users to build applications, modify the behavior of the phone, and use network service
Collaborative Proposal: Security Services in Open Telecommunications Networks
The goal of the project is to harness the information contained in users' interactions with information systems (e.g., query reformulations, clicks, dwell time) to train those systems to better serve their users' information needs. The key chal
III: MEDIUM: LEARNING FROM IMPLICIT FEEDBACK THROUGH ONLINE EXPERIMENTATION
Floer homology theory, a technique using partial differential equations to study problems in smooth / symplectic topology, were first introduced in the 1980's. Since then, these theories have led to many dramatic discoveries, including the reso
Structure of Low-Dimensional Floer Homologies
This proposal describes several major research thrusts related to algebraic invariants of structured ring spectra. In algebraic K-theory, the PI describes an approach to resolving the central conjectures of Waldhausen and Rognes that underpin a
Algebraic invariants of structured ring spectra, arithmetic, and geometry
This award supports theoretical research and education in condensed matter physics. The PI aims to further study a new kind of insulator predicted by theory. It has long been known that insulators do not conduct electric current. In the past 5
GENERALIZED LINEAR MODELS FOR LARGE CORRELATION MATRICES VIA PARTIAL AUTOCORRELATIONS
Quantifying, managing and pricing risk is not only important for the big players in the economy but has become increasingly important for every individual, who are trying to reduce the risk of outliving their wealth through their retirement fun
AMC-SS: Problems in Mathematical Finance
The principal investigator (P.I.) will study three topics in measurement error models, develop relevant methodologies and analyze their corresponding properties and performances.   The first topic concerns functional models in the situation whe
We propose to study the impact of interfacial interactions of polymers on charge transport in semiconducting polymers.  The proposed experiments will attempt to disaggregate, for the first time, the impact of molecular organization, dipolar int
This project studies classes of spatial-temporal covariance functions for nonstationary, multivariate processes on a globe. Many processes in geophysical and environmental problems these days take large portion of the Earth as their spatial dom
NONSTATIONARY SPAITAL-TEMPORAL COVARIANCE MODELS FORMULTI VARIATE PROCESSES ON A GLOBE
Under this award Drs. Lucy Ziurys and DeWayne Halfen (University of Arizona) will continue their investigation of the chemistry of the refractory elements through the ongoing joint laboratory/observational program. The laboratory investigations
Following Refractory Elements from Circumstellar Ejecta to the Interstellar Medium: A Combined Laboratory and Observational Study
Stochastic models of complex networks with dynamic interactions arise in a wide variety of applications in science and engineering. Specific instances include high-tech manufacturing, customer service systems, telecommunications, computer syste
AMC-SS: Stochastic Networks -- Analysis, Control and Applications
The objective of this research is to develop novel/improved methods for statistical model building and risk factor estimation when the training set has complex continuous and discrete attribute variables and including, but not limited to extrem
ARRA A New Paradigm for Multiple Correlated Outputs Given Dissimilarity and Other Information from Multiple Sources
NON-TECHNICAL DESCRIPTION:  Nanomagnetism is one of the most active areas in science with a wide range of fundamental scientific problems as well as emerging technologies. Many magnetic devices are still in their infancy and a thorough understa
The ability to conduct the targeted synthesis of a new solid-state compound is one of the grand challenges of the field of solid state chemistry.  This proposal targets the synthesis of new misfit layered compounds [(MX)m]1+x[TX2]n where M is a
Synthesis of and Structure-Function Relationships in New Misfit Layered Compounds
The discovery of high-temperature superconductivity in a class of oxide materials known as cuprates in 1986 had simulated intense worldwide research efforts because of high expectations for potentially a wide range of applications. Although mu
Spatially Resolved Quasiparticle Tunneling Spectroscopic Studies of Cuprate and Iron-Based High-Temperature Superconductors
The objective of this research project is the investigation and the mathematical analysis of a wide class of asymptotic problems for stochastic partial differential equations, with emphasis on the study of averaging principle, large deviation p
Asymptotic Problems for Stochastic Partial Differential Equations
As a single sheet of graphite, graphene has a number of exceptional properties, including: extraordinary mechanical properties, high thermal conductivity and excellent electrical conductivity. Combined with its very high specific surface area (
Graphene-based Materials for Ultracapacitance Applications
Proposal Title: Collaborative Research: Three-Dimensional Microstructural andChemical Mapping of Solid Oxide Fuel Cell Electrodes: Processing,Structure, Stability, and ElectrochemistryInstitution: Northwestern UniversityAbstract Date: 06/11/09T
Collaborative Research:  Three-Dimensional Mapping of Solid Oxide Fuel Cell Electrodes:  Processing, Structure, Stability, and Electrochemistry
Funds are provided to develop a better understanding of the processes and consequences of surface meltwater production on the Greenland ice sheet, particularly the development of surface lakes and their subsequent drainage to the subglacial bed
MODEL STUDIES OF SURFACE MELTWATER LAKES OF THE GREENLAND ICE SHEET
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  The influence of massive stars and accreting black holes on the surrounding interstellar medium, termed 'feedback', has been regarded as an impor
ARRA New Constraints on Feedback from a Comprehensive Study of Galactic Winds
Personnel in place: Dr. Alan Marscher (PI, professor) Dr. Svetlana Jorstad (co-I, senior research associate) Dr. Manasvita Joshi (PDRA) - new hire (9/1/09)to participate in the ARAA-funded project Dr. Ivan Agudo (PDRA) - new hire (2/1/10) to pa
The Most Compact Regions of Relativistic Jets in Active Galactic Nuclei
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). Under this award, supported by the Experimental Physical Chemistry Program of the Chemistry Division, Professor Ryszard Jankowiak from Kansas Stat
Comparative studies of electronic structure and dynamic process in model photosynthetic complexes using spectral hole burning and single complex spectroscopies
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  Speckle observations are proposed for a significant set of binaries drawn from the Hipparcos Catalogue and other sources. The Hipparcos mission d
Completing the WIYN Speckle Survey: Toward the Thin and Thick Disk Binary Populations
Investigators will conduct a series of 3-D magnetohydrodynamic simulations, to study how outflows from radio galaxies affect the surrounding gas, and to better understand the role of magnetic fields in regulating the temperature of the X-ray-em
MHD Instabilities and Radio-Mode Feedback in Intracluster Medium
This project will investigate the gas dynamics of protoplanetary disks, and the interaction of disks with planets. The work includes (1) studies of angular momentum transport by the magnetorotational instability (MRI) in protoplanetary disks, (
The mathematical modeling techniques and computational methods developed in this project will address key scientific challenges in applied mathematics including three-dimensional electromagnetic wave propagation in periodic chiral or nonlinear
Modeling, Analysis, and Computation of Diffractive and Nano Optics
Understanding Gamma-Ray Burst emission physics with multi-wavelength data This is a program to perform a multi-wavelength study of Gamma Ray Bursts (GRBs) to: 1. Systematically analyze GRB afterglow data, and clearly identify emission component
Understanding gamma-ray burst emission physics with multiwavelength data
Mathematical Problems in Collisionless Kinetic Theory: A collisionless plasma is a fully ionized gas in which electromagnetic forces are strong enough to dominate collisional effects. The motion of a high temperature, low density collisionless
Mathematical Problems in Collisionless Kinetic Theory
Very rapid change has been observed in the Polar Regions and is projected to continue for the foreseeable future. This change is ubiquitous across the system occurring within the atmosphere, terrestrial and marine components and encompassing th
Arctic Research Using the Community Climate System Model
'Dr Steidel will make a detailed study of the galaxies and gas within a few million light years of bright quasars that we observe as they were 10 billion years ago. Using the Keck telescopes, he will take high-resolution optical and near-infra
Densely Sampling the High Redshift Universe
This project has now been awarded a total of 400 hours of telescope time at Arecibo Observatory, out of which 300 hour have already been used.  Graduate student Kristen Thompson continues her analysis and interpretation of the data as well as h
Observations of Magnetic Fields in Molecular Clouds - Exploring Two Key Issues
Ferroelectric ceramics have unique properties, including piezoelectricity, pyroelectricity, the electro-optic effect, phase change, and polarization switching. These special properties make them useful for a wide range of technological applicat
Materials World Network: Experimental Observation and Theoretical Modeling of Domain Evolution in Ferroelectrics
Collaborative Research: A biotic awakening: How do invertebrates, microbes, and plants determine soil organic matter responses to release from nutrient limitation in arctic tundra?
Intellectual Merit: Expanded use of (U-Th)/He and 4He/3He thermochronology in tectonic and geomorphic studies over the last decade have elucidated several first-order challenges facing their practical application and interpretation. Quantitativ
Addressing Current Challenges in (U-Th)/He Thermochronology and Running Summer Student Workshops
This project involves the analysis of data from a temporary array of 11 three-component, broadband seismic instruments deployed in July 2008 in a 15 km diameter area centered on Katmai Pass, Alaska, supplemented by data from the surrounding Ala
ARRA Structure, Stress, Earthquake Sources, and Dynamic Triggering in Katmai, Alaska
Obtaining physiological/behavioral data from human subjects in natural environments is essential to the effectiveness and accuracy of social and behavioral research, such as ecologically valid studies of psychosocial stress, addictive cravings,
NETSE: LARGE: COLLABORATIVE RESEARCH: FIELDSTREAM: NETWORK DATA SERVICES FOR EXPOSURE BIOLOGY STUDIES IN NATURAL ENVIRONMENTS
Implementation of the FieldStream framework in several real-life wireless sensor systems, starting with the ones being led by us (AutoSense at Memphis, and Urban Sensing and UCLA).  It will help establish the feasbility of FieldStream for real-
NetSE: Large: Collaborative Research: FieldStream: Network Data Services for Exposure Biology Studies in Natural Environments
The purpose of this project is to demonstrate that chiral metal nanostructures can be grown on chiral metal oxide surfaces. If successful, it will provide an avenue for the design and development of new chiral separation technologies that would
Tailoring Enantiospecific Properties of Chiral Metal Nanoclusters on Chiral Metal Oxides
Emphasis on the elevated level of arsenic in groundwater tapped by millions of shallow tubewells across southern Asia over the past two decades has tended to obscure that anoxic aquifers that are low in As are also widespread and often within r
Collaborative Research: Enhancing the sustainability of groundwater pumping from low-arsenic aquifers in southern Asia - a case-study in Vietnam south of Hanoi
Vadose-zone soil moisture is an important driver of processes in agricultural, hydrological, ecological, and climate systems, yet the detailed nature of plant water use across ranges of scales is often poorly characterized. With projected chang
Multi-scale Monitoring and Modeling of Land Use and Climate Change Impacts on the Terrestrial Hydrologic Cycle: Implications for the Great Lakes Basin
One of the unsolved paradoxes in the earth sciences is how fluid-assisted mass transfer occurs at convergent plate boundaries. Subduction causes rapid P-T changes in the downgoing slab and juxtaposes rocks of very different geochemical characte
Linked Isotopic (Cl, O, H) and Petrologic Studies of Fluid-rock Interaction During the Subduction Cycle
This project will entail an integrated, multi-disciplinary approach involving PIs and collaborators with diverse expertise and perspectives. The project will combine extensive field work, elemental and isotopic analyses of rock, glass, mineral,
MAGMA CHAMBERS, & PLUTONIC RESIDUE: Insights from Peach Spring Tuff, Significance of Sphene
The title of the project is 'Investigating the mechanics of conjugate strike-slip faults and its implications for continental deformation'. The work consists of three components: (1) field investigations mapping the geometry and kinematics of a
COLLABORATIVE RESEARCH:  GEOLOGICAL INVESTIGATIONS OF NON-ANDERSONIAN CONJUGATE STRIKE-SLIP FAULTS IN CENTRAL TIBET
Improved Manufacturing Method for Carbon Nanofiber Production INTELLECTUAL MERIT:  This SBIR Phase I project will investigate the effectiveness of forming carbon nanofibers by a gas jet process.  The beneficial properties of carbon nanofiber re
Improved Manufacturing Method for Carbon Nanofiber Production
This collaborative research project is being undertaken by Dr. Gerta Keller, Princeton University, and Dr. Abdel Aziz Tantawy, South Valley University in Egypt, to collect the necessary long-term biotic, mineralogical and geochemical records ne
US - Egypt Cooperative Research: Climate Change and Biotic Effects During the Late Cretaceous of Egypt
aims to establish cost-effective methodologies for the efficient production of anthocyanins from genetically engineered bacteria.  Anthocyanins are plant secondary metabolites that are mainly responsible for the colors in plant tissues, primar
SBIR Phase I: Microbial Production of Selected Anthocyanins
ADVANCED TECHNOLOGY AND RESEARCH CORPORATION
This Small Business Innovation Research Phase I research project focuses on the development of several technical capabilities for the class of open-frame, cable driven robots and demonstrates these capabilities in a practical boat maintenance a
SBIR Phase I: Cable-driven Manipulator for Light Manufacturing and Service Applications
CoolCAD Electronics LLC was awarded a Phase I SBIR contract from the National Science Foundation (NSF) to carry out research into development of Silicon Carbide (SiC) based power device and circuit computer-aided-design tools and prototype DC-D
SBIR Phase 1: Development of Silicon Carbide Power Device and Circuit CAD Tools and Prototyping of SiC Based Power Converters for Hybrid Vehicles and Power Electronic Applications
This Small Business Innovation Research Phase I project will investigate a new transgenic approach to inducing sterility in economically important species, with initial application in aquaculture.  There is a need for improved performance and r
SBIR Phase I: Transgenically Mediated Sterility by Targeted Germ Cell Ablation
This project is to develop advanced numerical techniques in order to perform efficient, accurate and state of the art simulations for two-phase transport model in the cathode of hydrogen proton exchange membrane fuel cell (PEMFC). The computati
Efficient numerical techniques of two-phase transport model in the cathode of hydrogen pollymer electrolyte fuel cell
The objective of this project is to develop fast and robust numerical reconstruction methods for linear and nonlinear inverse transport problems appeared in many application areas. The main approach proposed is to incorporate a priori informati
Numerical Methods for Inverse Problems of the Linear Boltzmann Transport Equation
The proposal requests numerous Shipboard Scientific Support (SSSE) items for the vessel operated by Oregon State University (OSU), namely the R/V WECOMA. The requests specifically include items that have been recommended from past NSF inspectio
Shipboard Scientific Support Equipment 2009
Principal component analysis (PCA) has long played a central role in dimensionality reduction and compression. However, the fact that PCA is a data-dependent transform that is traditionally determined via a computationally expensive eigendecomp
CIF:  Small: Sompressive-Projection Principal Component Anaylsis
Multicore processors have become main-stream. At the same time, CPU clock rates are no longer increasing. Operating within this environment, application developers are under competitive pressure to parallelize software in order to achieve an ac
CSR: Small: New Slicing Techniques for Program Parallelization
The proliferation of multiple cores on the same die has given rise to communication-centric systems, wherein the design of the interconnection network has become extremely important. To address the growing wire delay problems and improve perfor
SHF: Small: Collaborative Research: Design of Power and Area Efficient, Fault-tolerant Network-on-Chip Circuits and Architectures
This research program is motivated by the recognition that the volume of sensor data is expected to overwhelm even the enormous performance improvements in silicon technology expressed by Moore`s Law. The focus is the development of a low-compl
Robot hands are usually simple, with just two or three fingers, perhaps a single actuator, and most often no sensors at all. These simple hands are also very specific in their function, such as picking up a specific part. Research on more gener
This project focuses on the development of a new binary rewriter that can be use to statically transform binary code that does not have relocation information and to do so without the overhead of dynamic binary rewriting. Binary rewriters are p
CSR: Small: Binary rewriting without relocation information
NeTS: Small: Collaborative Research: Transmission Reordering in Wireless Networks: Protocols and Practice The edge of the Internet continues to spread rapidly over the wireless medium. To cope with the escalating demand, every available opportu
NeTS: Small: Collaborative Research: Transmission Reordering in Wireless Networks: Protocols and Practice
This project develops novel methods for integrating image and non-image geospatial data to 1) advance the state-of-the-art of automated remote sensed image analysis and, in turn, 2) improve the coverage and fidelity of the non-image repositorie
III:Small:RUI: Integrating Image and Non-Image Geospatial Data
The project will develop efficient mechanisms for deploying and managing wireless self-organizing networks (WSONs). These networks are able to manage themselves with little or no human intervention and consequently can be deployed in remote, di
NetSE: Small: Collaborative Research: A Geometric Computational Approach to Efficiently Deploy and Manage Self-Organizing Wireless Communication Networks
Increasingly, computation and storage are moving into a planetary cloud accessible across ever-widening Internet pipes. Unfortunately, asynchrony, failures, and heterogeneity make it difficult to harness available computing power and storage, w
CSR: Small: System Support for Planetary Scale Services
This project addresses the complex networking challenge presented by the emerging cloud computing model. Cloud providers must run a diverse set of client applications, each with potentially different networking demands, on shared data-center fa
NeTS: Small: Topology Switching for Data Centers and the Clouds Above
Project is to design, implement and evaluate the personal wellness platform called Health Guardian (HG).   The Health Guardian concept introduces a paradigm shift in wellness monitoring - from traditional client to server model to location/env
NETSE: SMALL: COLLABORATIVE RESEARCH: THE HEALTH GUARDIAN - A GATEWAY TO NETWORKED WELLNESS
Heritage speakers are adults who grew up hearing and even speaking a language other English but who are now more comfortable in English. Recent studies of heritage speakers have documented incomplete acquisition of aspects of inflectional morph
Differential Object Marking in Spanish Hindi and Romanian Heritage Speakers
Grant funding applied towards the purchase of three public safety pole cameras and monitoring equipment.  Funding was also applied towards the utility service necessary to provide a live feed to be viewed by police personnel.
Speedway Police Department Public Safety Camera Initiative
LGPD/UCSO Equipment Upgrade. The goals of the project are 1-To improve protection and safety of law enforcement officers. 2-Improve prosecution and conviction rates by providing video evidence. 3-To reduce officer and department liability by ha
Project enable us to get CAD for dispatch and mobile computing, update computer equipment and begin working towards compliance of digital communications.
FY 2009 Recovery Act JAG Program - purchase of in-car video and radar system and radar units in patrol vehicles and overtime; purchase of 2 certified full patrol canines, equipment, supplies and vet costs; purchase of improving technology equip
Equipment purchases to enhance service levels.
1. Reduce the number of underage drinking and driving arrest. 2. Target the increase of drugs traveling through our county to avoid arrest on I-75 3. Identify and reduce new gangs in the county.
Brooks County Sheriff's Office Drug and DUI Reduction
The purpose of the award is to preserve and create jobs and promote economic recovery, to assist those most impacted by the recession, to provide investments needed to increase economic efficiency by spurring technological advances, and to stab
The award will be utilized to modernize and update multiple underlying municipality police equipment with the tools necessary for the municipalities to maintain an adequate state of readiness and enhance officer safety while servicing the publi
The desired impact for this award is to allow officers to have the ability to access information quicker as relative to their job tasks. Reports, citations etc. can be written in the field and downloaded to the Police Deaprtment allowing them t
The Alexander County Sheriff's Office will utilize award funds to implement projects to fund part-time officer's salaries to work in the court-security division of the Sheriff's Office as well as to upgrade existing radio communications equipme
2009 Alexander County Sheriff's Office Recovery Act JAG Funding
This award will be used partly to enhance the Corrections Security Program by purchasing additional security system equipment for the Ontario County Correctional Facility.  The additin of this equipment will enhance the detection of narcotics,
Enhanced Drug Enforcement and Corrections Security System
Award will be used to purchase a new police cruise and two additional camera systems for patrol cars.
Vehicle and Digital Camera Purchase Program
Prime Recipient - Public Safety AVL System (Automated Vehicle Locater) The purchase of the AVL system was for Public Safety Vehicles to allow Central Dispatch to locate all Public Safety vehicles at all times, in real time, in any case of any e
FY 2009 Recovery Act JAG Program / BJA FY 09 Recovery Act Edward Byrne Memorial Justice Assistance Grant Program Local Solicitation
The Justice Assistance Grant (JAG) Program allows states, tribes, and local governments to support a broad range of activities to prevent and control crime based on their own local needs and conditions.
BJA FY 09 Recovery Act Edward Byrne Memorial Justice Assistance Grant Program Local Solicitation - Weapon Replacement and Safety Initiative.  Beaufort County Sheriff's Office will use their funds to purchase 58 new handguns complete with lights
Weapon Replacement and Safety Initiative
The Collin County Sheriff's Office, Allen PD, Frisco PD, McKinney PD, Plano PD and Wylie PD will use the JAG Recovery Act Funds to purchase equipment to enhance the department's ability to detect and deter crime, and to respond to emergency sit
The enhancement of equipment, technology, and training projects for the City of Morgantown and for the County of Monongalia, WV.
Purchase equipment for the new Combined Communications Center.
Sweetwater County Combined Communications Center
The Arlington County Police Department (ACPD) and its subrecipient, the Arlington County Sheriff's Office (ACSO) are using FY 09 Recovery Act Justice Assitance Grant funds to purchase new equipment, replace obsolete and/or outdated equipment, a
Law Enforcement Equipment Enhancement Program
Purchase of radar and in-car camera systems for patrol cars.
Purchase of radars and in-car camera systems
Funds obtained in this grant will be used to train and equip Sheriff's Office personnel on the use and operation of technology based equipment in order to better detect, document, and prosecute crimes.
Increased use of Technology in Rural Policing
The Justice Assistance Grant (JAG) Program funded under the Recovery Act is the primary provider of federal criminal justice funding to state and local jurisdictions.  Recovery JAG funds support all components of the criminal justice system, fr
Criminal Justice Initiative in Ramsey County
Funding to purchase new firearms, holsters and gunmounted lights to replace obsolete equipment for full time sworn personnel.
Purchase of new firearms and holsters for police officers
Technology Enhancement - Holland Police Department
Law Enforcement and security equipment purchase and upgrades
Upgrade radio towers to improve electronic storage, security upgrades and improve communications capability
The Lynchburg Department of Emergency Services has completed staffing studies that showed additional staffing was required to maintain the current level of Public Safety dispatch services being provided.  Increases in the time spent during call
The DENVER SHERIFF Juvenile Psychologist completed comprehensive intakes for 3 juveniles who entered the program (all three received a clinical interview and filled out the MAYSI-2 screening tool).  Juveniles were screened for appropriate educa
Funding to provide training and equipment necessary to reduce and supress crime in Bloomfield, NM. To date expenditures/purchases have included Staff/Command and active shooter trainings as well as  stop stick kits, Tasers, helmets, vests, medi
THe purpose of this project was to upgrade communications infrastructure to meet the FCC narrowband mandate
McDuffie County Public Safety Interoperability Project
The Topeka Police Department received funding for 7 new officers through the COPS Office to backfill positions we moved into a Community Policing Unit.  The JAG Recovery Grant supplied the 7 new officers with new equipment and 6 new vehicles an
TPD- Topeka Community Policing Expansion Project (TCPEP)  SSO- Telephone System Enhancement Project (TSEP) DOC- Internal Security Enhancement Project
2009 Recovery Act JAG Program Story County Law Enforcement Safety Initative. Programs to promote officer, facility and public safety in Story County, IA.
Story County Law Enforcement Safety Initative
The disparate jurisdictions consisting of Clark County and the cities of Las Vegas, North Las Vegas, Henderson and Mesquite will use their Recovery Act JAG award in the amount of $7,558,206 to support personnel, equipment purchases, and multi-d
Byrne FY09 JAG Local Solicitation. Approved projects include multiple equipment purchases and hiring of part-time personnel by one agency.
BJA FY09 Recovery Act Edward Byrne Memorial Justice Assistance Grant Program Local Soliciation
The Charter Township of Flint, serving as the fiscal agent for this award, will share the Recovery Act JAG funds with 12 disparate jurisdictions within Genesee County. In a disparate situation, the units of local government must apply for an aw
2009 Genesee County Recovery Act JAG Project
ARRA 'ALL IN ONE' GRANT`S PURPOSE IS TO ENHANCE, UPGRADE,  AND OBTAIN NEEDED EQUIPMENT FOR DEPUTIES AND TO ENHANCE OUR CURRENT PRISONER RE-ENTRY PROGRAM.
The Justice Assistance Grant (JAG) is a formula grant awarded annually to states and local jurisdictions to be used for law enforcement purposes.  Allocation of Funds:  Total Allocation for Mecklenburg County			$4,453,144 City of Charlotte:
Criminal Justice System Improvements (JAG)
FY09 Recovery Act JAG Program will support overtime enforcement with a combination of proactive intelligence gathering through threshold inquiries and field interviews, and a zero intelligence approach to narcotics offenses, public disturbances
Walton County law enforcement has a duty to provide its citizens with adequate protection and quality service. Both the County Sheriff?s Office and central seated Monroe City are faced with an equipment crisis. Both departments are in need of u
Walton County Sheriff's Office Zone Community
The County of Dakota and sub-recipient cities seek to protect the safety of the public and promote economic recovery.  Funds provided by this grant will be used to purchase camera equipment, squad cars, and other equipment and supplies to furth
Law enforcemetn equipment, technology, police cruisers, and related police equipment.
Project Summary   The city of Lansing, serving as the fiscal agent for this award, will share its Fiscal Year 2009 Recovery Act JAG award with four disparate jurisdictions within Ingham County. In a disparate situation, the units of local gover
JAG2009 INCREASED TECHNOLOGY FOR INGHAM COUNTY SYSTEM OF JUSTICE
This project will be used to upgrade the Mexia Police Department's communications system and to purchase patrol equipment for the Limestone County Sheriff's Office
Communications Upgrade and Patrol Equipment Purchase
The Edward Byrne Memorial Justice Assistance Grant (JAG) Program funds support all components of the criminal justice system, from multi-jurisdictional drug and gang task forces to crime prevention and domestic violence programs, courts, correc
Muskegon County, serving as the fiscal agent for this award, will share the Recovery Act JAG funds ($431,974) with five disparate jurisdictions within the county. In a disparate situation, the units of local government must apply for an award w
Personnel and support equipment for select law enforcement jurisdictions within Muskegon County, Michigan
Funding has been used for the purchase of portable radios to further emergency communication interoperability both within the Town and with surrounding municipalities and Palm Beach County.
'The Ridgecret Police Department will use Recovery Act JAG funds to initiate a Narrowband Radio Project.  The goals of this project are to comply with the federal Communications Commission narrow banding mandates and to acheive true interoperab
To purchase and install mobile radios in patrol vehicles.
Spotsylvania County will use Recovery Act JAG funding to provide training, equipment, and supplies for the Spotsylvania County Sheriff's Office.
FY 2009 Recovery Act Justice Assistance Grant
Laptop and cruiser technology for enhancement of law enforcement safety and communications.
Purchase of in-car printers and video cameras.
Technical Enhancements for Improved Procecution Data Flow
Purchase of patrol vehicle and electronic ticketing system.
2009 Local JAG for AHRT Member Safety and Preparedness   The main purpose of the application for this grant is to purchase the necessary equipment for the Garfield County All Hazards Response Team's continued availability.  With the monies rece
This grant program is authorized by the ARRA of 2009.The state purposes of the Recovery Act are: to preserve and create jobs and promote economic reconvery; to assit those most impacted by the recession; to provide investment needed to increase
purchase of police vehicles for various municipalities
Washington County Law Enforcement Upgrade Program
The purpose of this grant is to stimulate the local/national economy by making purchases and small physical changes to the Brattleboro Police Dept.
purchase of police vehicle for patrol, crime prevention and emergency response
Department of Justice, Office of Justice programs, Bureau of Justice - JAG Program
Camden County Recovery Act (JAG) Project
City of Franklin. TN Police Department Professional Development and Training
We recently demonstrated that soon after Bacillus anthracis spores are delivered into mouse lungs significant quantities of these spores are found inside the lung epithelial cells. Here we hypothesize that this intracellular presence plays an i
THE ROLE OF LUNG EPITHELIUM IN B. ANTHRACIS PATHOGENESIS
More than 2 million children and youth in the U.S. are homeless at some time each year. Once on the streets, homeless youth frequently rely on high-risk survival behaviors to meet their basic needs. Compounding these high-risk behaviors, these
Engaging Homeless Youth in Vocational Training to Meet Their Mental Health Needs
Functional Consequences of Developmental Myosin II Down-Regulation in Neurons
The pancreatic ?-cells are responsible for producing insulin and maintaining glucose homeostasis.  A loss of ?-cells or their inability to compensate for insulin resistance is the major cause for type I and type 2 diabetes, respectively. Increa
Cross-Talk between Mesenchymal Cells and Beta-Cells During Islet Regneration
Abstract Serotonin (5-hydroxytryptamine; 5HT) has been demonstrated to play important roles in various physiological functions such as mood, sexual behavior, feeding, sleep/wake cycle, memory, cognition, blood pressure regulation and breathing
Investigation of Gi/o signaling in the 5HT system
Chronic wounds, such as diabetic wounds, are a major global health and economic burden. In the United States alone, 10.8 million chronic wounds occur every year (de Zoysa et al., 2005) which is estimated to cost over $15 billion annually in the
The worldwide market for implant-based dental products is forecasted to approach $3.5 billion by 2010, and although only 9% of the global dental market is allocated to dental implants, it is the fastest growing segment at a rate of 15% per year
Development of a niobium oxide as a potential coating for dental and orthopedic implants
Electroplating, Plating, Polishing, Anodizing, and Coloring
Award title: Endomyocardial catheter delivery of artificial biopolymer matrices for enhanced cell retention in cardiovascular cell based therapy.  The overall purpose of this project is to identify formulations of two-component biopolymers incl
Endocardial catheter delivery of artificial biopolymer matrices for enhanced cell retention in cardiovascular cell based therapy.
The objective of the recovery award is to allow LEEOAT Company to develop, design, theoretical model, fabricate and test our innovative volumetric imagers, to support noninvasive real-time guiding of medical catheters during clinical therapeuti
Micromachined 7MHz Two Dimensional Forward Looking Ultrasound Penetrative Imager
The Title of the project is Multiparameter Fiber Optic Breathing Sensor.  The goal of this project is to develop a device to detect periodic breathing, or brief central or obstructive apnea, assocaited with hypoxemia for infants at risk of sudd
Multiparameter Fiber Optic Breathing Sensor
Antigenically-naïve CD4 T cells expressing alpha/beta-T-cell receptors are critical for generating immune responses to neoantigens, and are produced de novo within the thymus as mature CD4+CD8- thymocytes. These enter the periphery to become r
RECENT THYMIC EMIGRANTS OF THE CD4 T-CELL LINEAGE
To survive within the hostile environment of the infected host, pathogenic microorganisms must be able to sense and adapt to changing environmental conditions. This adaptation requires a coordinated regulation of multiple factors for growth and
COORDINATED REGULATION OF VIRULENCE GENES IN C. NEOFORMANS
The host response to pathogenic insults involves complex inflammatory responses and cellular immune reactions, such that the decision to generate protective immunity or tolerance often depends on the context in which T cells first encounter ant
Apoptotic Cells Induce Tolerance Through TRAIL-Expressing CD8+ Regulatory T Cells
As new HIV infections continue to occur at alarming rates, development of a strong and effective mucosal vaccine would have a huge public health impact. Thus there is a continuing need for new approaches for HIV-1 vaccination. This project focu
NOVEL HETEROLOGOUS LISTERIA-ADENOVIRUS MUCOSAL VACCINE FOR HIV-1
Streptococcus Pneumoniae is the most common bacterial respiratory pathogen in human immunodefficiency virys (HIV) infected persons. The incidence of Pneumococcal disease is significantly elevated, 35 -100 folds, in HIV-positive population. Purp
IMMUNE RESPONSE TO PNEUMOCOCCAL VACCINATION IN HIV INFECTED ADULTS
Bacillus anthracis, the causative agent of anthrax, is a highly pathogenic bacterium considered to be a serious threat as an agent of bioterrorism.  The recent use of this bacterium as a terrorist weapon in the United States exposed the need fo
STRUCTURE AND FUNCTION OF THE B. ANTHRACIS EXOSPORIUM
Our overall goal is to identify novel components of the host innate antiviral response and novel mechanisms by which viruses subvert this response to cause disease. Cardiac myocytes are non-replenishable; thus the heart is unusually dependent o
Reovirus Modulation of the Cardiac Innate Response: Type I Interferon and HSP25
Taken from Grant Abstract - Understanding the interplay between pancreatic alpha- and beta-cells that exerts local control on glucagon secretion is the focus of this application.  Blood glucose levels are controlled primarily by two hormones, i
The objective of the project is to evaluate the role of protein carbonylation in mitochondrial dysfunction and insulin resistance in adipocytes.
Mitochondrial Dysfunction and Adipose Insulin Resistance
THE HOSPITAL FOR SPECIAL SURGERY FUND INC
.  Patients will be identified through existing hospital discharge databases for New York and California.  The effects of patient and institutional (surgeon and hospital) factors will be evaluated.  In order to address the 3 specific aims, thes
Referral Patterns and Risk of Early Revision After Primary Total Joint Arthroplasty
The purpose of this study is to examine whether the manner in which parents interact with their preschool children and  parents' and children's responses to stress, in combination with how they think about stressful social situations, influence
Biopsychosocial factors in economically disadvantaged preschool children's adjustment
This application addresses the broad Challenge Area (04) Clinical Research and the NIA specific Challenge Topic 04-AG-105: Development of experience-based measures of well-being. There is an interdisciplinary resurgence of interest in the corre
EXPERIENCED-BASED AND SUBJECTIVE WELL-BEING SURVEY TOOLKITS FOR OLDER ADULTS
This ARRA Challenge Grant application addresses Broad Challenge Area (05) - Comparative Effectiveness Research and Specific Challenge Topic 05-AG-105 - Comparative Intervention Trials for Diseases and Syndromes of Aging Including Neurodegenerat
Neural Effects of Exercise, Cognitive, or Combined Training in AD At-Risk Elders
This application addresses broad Challenge Area (06) Enabling Technologies and Specific Challenge Topic, 06-AG-101: Neuroscience Blueprint: Development of non-invasive imaging approaches or technologies that directly assess neural activity. As
FUNCTIONAL ACTIVITY MAPPING OF BRAIN NETWORKS
Epigenetic Analysis of iPS Cell Models of Aging and Alzheimer’s Disease The overall purpose of this award is to advance our understanding of cognitive decline associated with aging and Alzheimer’s disease (AD). The award will promote this g
Epigenetic Analysis of iPS Cell Models of Aging and Alzheimer's Disease
The goal of this study is to examine the hypothesis that alterations in neurogenesis occur in a specific manner in Alzheimer’s disease and are manifested by an imaging-detectable impairments and by alterations in neurogenic gene expression. T
Comparative effectiveness of Brain Imaging and Blood Biomarkers in Alzheimer's disease
This 'Challenge grant' application addresses the Broad challenge area: translational science: Specific challenge topic: 15-NS-103. Demonstration of 'proof of concept' for a new therapeutic approach in a neurological disease. Our goal is to util
Peripherally Aministered Gene Therapy for Alzheimer's
This application addresses broad challenge area (15) Translational Science and specific Challenge Topic, 15-AI-106: translational research focused on high priority pathogens and basic research focused on resistance mechanisms. The research desc
DEVELOPMENT OF A UNIVERSAL INFLUENZA VIRUS VACCINE
Tuberculosis (TB) is one of the world’s deadliest infectious diseases, and co-infection with HIV plus the emergence of drug-resistance have made TB both difficult and expensive to treat.  In order to create new TB drugs, we need to understand
Inhibition of the Nonmevalonate pathway to Kill Mycobacterium Tuberculosis
Neglected tropical diseases are a group of 13 major disabling conditions that are among the most common chronic infections in the world's poorest people.  Chief among these are the five main diseases caused by nematode worms, accounting for mor
Microfluidic devices for high-throughput anthelmintic screens
Autoimmune diseases are estimated to afflict as many as 50,000,000 Americans. This proposal tests genetic and serologic biomarkers of autoimmunity, cytokine activity, and abnormal environmental responses as predictors of autoimmune disease onse
Predicting Systemic Autoimmunity through Follow-up of Blood Relatives
This application addresses broad Challenge Area (04) Clinical Research and specific Challenge Topic 04-AR-101 Autoimmunity for Diseases of Skin, Joints, Muscles and Other Tissues. It is estimated that approximately 5% of the US population is af
High Throughput Screening of Autoimmune Epitome - ARRA Stimulus Challenge Grant
Statins markedly reduce the incidence of cardiac events. These drugs are generally well-tolerated but can produce a dose-related myopathy with symptoms ranging from ?mild? myalgia, muscle cramps and weakness to life-threatening rhabdomyolysis.
This application addresses Challenge Area (01) Behavior, Behavioral Change, and Prevention and Specific Challenge Topic, 01-CA-103, The Role of Health Behaviors in Cancer Prevention. Research shows that telephone quitlines are effective smoking
ARRA Improving the population-wide effectiveness of U.S. tobacco cessation quitlines
Modulation of cancer prevention by social stress'. This project will test the hypothesis in xenografts of the human lung adenocarcinoma cell lines NCI-H322 (with ras mutations) and NCI-H441 (without ras mutations) and the human pancreatic ducta
MODULATION OF CANCER PREVENTION BY SOCIAL STRESS
Head and neck squamous cell carcinoma (HNSCC) is a devastating disease that is treated aggressively when diagnosed at late stages. Treatment includes at least two and at times all three modalities of surgery, radiation, and chemotherapy. Due to
Human in Mouse Modeling of HNSCC to Predict Response to Therapy
The development of hormone resistance in breast cancer is a significant clinical problem. The enhanced expression of the ErbB2/3 heterodimer leads to the ability of breast cancer cells to bypass normal endocrine responsiveness. However, the use
A novel therapy for HER2 positive hormone refractory breast cancer
This application fits the broad Challenge Area (01): Behavior, Behavior Change, and Prevention (01); and specific Challenge Topic 01-CA-103: The role of health behaviors in cancer prevention. Skin cancer incidence is rising more rapidly than an
Youth produced videos to reduce UV exposure in adolescents
Lymphoid neoplasms are among the most common malignancies in humans, and, for reasons that remain obscure, their incidence has been increasing over the past two decades. Although these disorders arise from diverse etiologies, chromosomal transl
Spatiotemporal control of recombination by the RAG proteins and ATM
The research project plans to perform a comprehensive detection of fusion transcripts in acute myeloid leukemia, with the aims to identify new genes contributing to this disease and to identify new markers for clinical diagnosis, treatment and
Comprehensive Identification of Fusion Transcripts in Leukemia
Lung cancer is the leading cause of cancer related deaths in the United States. Despite similar risk factors, African-Americans have higher incidence and mortality rates from lung cancer than other populations. Numerous studies have recently de
Polymorphism and Mutation Spectrum in Minorities with Non-Small Cell Lung Cancer
This study proposes to compare surgical treatment options for localized prostate cancer (MRP vs ORP) in terms of perioperative outcomes and cost, using several large national data resources and prospectively collected data from a large-volume s
Comparative Analysis of Surgical Treatment Options
This Challenge Application is directly and completely responsive to Specific Challenge Topic: 03-CA-102 ?Biologic Predictors of Progression in Barrett?s Esophagus?. It comes from a research team with more than two decades of experience investig
Predictors of Progression from Barrett's Esophagus to esophageal adenocarcinoma
This application addresses broad Challenge Area (05): Comparative Effectiveness Research and Specific Challenge Topic 05-CA-102: Comparative Effectiveness Research on Cancer Screening. Colorectal cancer (CRC) is the fourth most common cancer an
CT Colonoscopy Screening for CRC: Comparative Effectiveness vs Traditional Models
This application addresses broad Challenge Area (01) Behavior, Behavioral Change, and Prevention and specific Challenge Topic, 01-AA-103: Capturing Social Network Information for Groups at High Risk for Negative Health Behaviors. NIH has identi
Virtual Network Influences on Young Adults' Alcohol and Drug Use
This application addresses two broad Challenge Areas, (05) Comparative Effectiveness Research and (09) Health Disparities, and specific Challenge Topics, 05-MD-102  Prevention of Chronic Diseases in Disparity Populations , and 09-DA-101 Health
This application addresses the broad Challenge Area (01) Behavior, Behavioral Change, and Prevention and the specific Challenge Topic, 01-DA-106: Development of behavioral and social interventions that reduce stigma and improve quality and acce
Development of Behavioral and Social Interventions that Reduces Stigma and Improve Quality and Accessibility of Health Care Services in Low Resource Settings
This application addresses Challenge Area (01) Behavior, Behavioral Change, and Prevention and specific Challenge Topic, 01-DA-104: Functional Roles of Glia-Derived Factors in Mediating Drug Abuse. In line with NIDA's mission to support researc
Pre-clinical testing ofa  novel immunotherapy (recombinant T cell receptor ligand)
The human mouth is colonized by a microbial community of enormous complexity that plays a key role in human health and disease. Dental plaque is a biofilm constructed and inhabited by microbes, and the oral microbial community is involved in th
COMBINATORIAL IMAGING OF THE ORAL MICROBIOME
Orofacial clefts, specifically cleft lip and cleft palate, are common and costly congenital anomalies whose etiologies remain largely unknown.  One of the most promising clues to the causes of orofacial clefts is that women who use vitamins con
Methyl Donor Pathway Genetics in the Development of Orofacial Clefts
This is a Challenge application submitted in response to an RFP in the ARRA. We proposed to do transformative genome-wide studies of relating circadian transcription factor binding to biological rhythms and metabolic pathways.
Genome-wide epigenetic control of circadian metabolism by heme receptor Rev-erb
The ultimate goal of the work proposed is to develop a stepwise protocol for the differentiation of human iPS cells into renal progenitor cells. A distinct population of renal progenitor cells could serve as a starting point for subsequent diff
Inducible pluripotent stem cells and kidney regeneration
The primary focus of this Challenge Proposal is to identify the signaling pathways that control regulatory processes of neural crest (NC) migration and differentiation which generate the neural elements of the lower urinary tract (LUT). There i
Gene Networks in Neural Crest-derived Innervation of the Lower Urinary Tract
This application addresses the broad Challenge Area (06) Enabling Technologies and the specific Challenge Topic, 06-GM-105: Small RNAs. Nearly 60% of the US adult population is either obese or overweight. Clearly understanding the fundamental m
SMALL RNAS: REGULATION AND REGULATORY ACTIVITY IN BODY WEIGHT CONTROL
Autosomal recessive cystic kidney diseases are rare genetic disorders that produce kidney failure in children. No specific treatment currently exists. This proposal will test the feasibility of treating these disorders using a new technology, m
MicroRNA-Based Therapeutics for Rare Cystic Kidney Diseases - ARRA Stimulus Challenge Grant
This application addresses broad Challenge Area (04) Clinical Research and specific Challenge Topic, 04-HD- 102: Development of Pediatric Medical Devices. The title of this project is “Kidney Injury and Dysfunction Support (KIDS) - Developmen
Kidney Injury and Dysfunction Support (KIDS)
In this study, we propose to perform the first genome-wide association study (GWAS) for Immunoglobulin A Nephropathy (IgAN, OMIM %161950), an understudied disease that is a major cause of kidney failure in the U.S. and worldwide. It is the most
A GWAS for IgA Nephropathy, the Most Common form of Glomerulonephritis
Determination between benign and malignant strictures in the bile ducts is difficult.  Although non-invasive imaging modalities can locate the stricture, a definitive diagnosis cannot be made without an optical measurement of cells and tissue a
LASER ENDOSCOPY FOR GUIDED BIOPSY IN THE BILE DUCT
Developing and validating assistive neuro-technologies: 06-NS-104 Abstract/summary: Development and Translational Assessment of a Tongue-Based Assistive Neuro-Technology (ANT) for Individuals with Severe Neurological Disorders. More than two mi
ARRA: DEVELOPMENT AND TRANSLATIONAL ASSESSMENT OF A TONGUE-BASED ASSIST...
This project addresses broad Challenge Area (15) Translational Science and specific Challenge Topic, 15-ES-101: Effects of environmental exposures on phenotypic outcomes using non-human models.  Since the 1970's, adverse health effects have bee
Mechanisms for Cardiovascular Effects of air polutants.  Effects of Age and Sex.
This application addresses broad Challenge Area (12) Science, Technology, Engineering, and Mathematics Education (STEM) and specific Challenge Topic 12-ES-101: Material Development for Environmental Health Curriculum. K-12 students share the pu
RECRUITING THE NEXT GENERATION OF ENVIRONMENTAL TOXICOLOGISTS
ARRA - Computational and Cell Culture Models for Mucus Clearance The lung inhales over 1 million infectious and toxic agents each day. The defense of the lung begins with the layer of mucus that lines the epithelial cell layer. When these assau
ARRA - Computational and Cell Culture Models for Mucus Clearance
This proposal describes the development of a gene regulation system in the context of AAV gene therapy for age related macular degeneration (AMD). AMD is a growing disease and a major cause of visual disability in the aging population with a si
Regulated Transgene Expression in the Retina
A novel hybrid ion mobility/linear ion trap mass spectrometer having unique capability for characterizing the structures of complex biomolecules will be constructed. It will then be applied to the analysis of prototype glycan isomers and glycan
New Ion Mobility/Photodissociation Techniques for Analyzing Glycans
This application addresses broad Challenge Area 06: Enabling Technologies and specific Challenge Topic 06-GM-101: Structural Analysis of Macromolecular Complexes. It focuses on the multiprotein Mediator complex, which has been implicated as a c
Structure-Function Studies of the Modular Human Mediator Coactivator Complex
This application addresses broad Challenge Area (06) Enabling Technologies, and specific Challenge Topic 06-CA-102: Transient Molecular Complexes in Cancer. Virtually all cellular processes, including those involved in cell growth, differentiat
CAPTURE OF UBIQUITIN CONJUGATION AND DECONJUGATION ENZYME SUBSTRATES
This application addresses broad Challenge Area (06) Enabling Technologies and specific Challenge Topic, 06-GM-101: Structural analysis of macromolecular complexes. We plan to develop a new method for atomic structure determination of proteins
CRYSTALLOGRAPHY WITHOUT CRYSTALS: ATOMIC STRUCTURE DETERMINATION OF LASER ORIENTE
JCVI will develop a method to measure gene expression in individual cancer cells obtained from human blood.  These circulating cancer cells (CTCs) are very rare but can be responsible for the spread of cancer throughout the body by metastasis.
Transcriptomics from Single Circulating Tumor Cells
This application addresses the Challenge Area (03) Biomarker Discovery and Validation. The specific topic covered in this application is the high priority topic entitled: 03-HL-101 Identify and validate clinically relevant, quantifiable biomark
Innate Immunity, Biomarkers and Myocardial Infarction
DESCRIPTION (provided by applicant: Chronic inflammation is a major contributor to the onset and progression of atherosclerosis and other vascular disorders. Studies of inflammation have focused primarily on the initiating processes and less at
Novel mouse models of inflammation-resolution
This application addresses broad Challenge Area (04) Clinical Research and specific Challenge Topic, 04-HL- 105: Treatment of Heart Failure with Preserved Systolic Function Multiple advances in pharmacological and device therapies have been mad
Management and Outcomes of Heart Failure with Preserved Systolic Function
This proposal responds to the broad challenge area (04): Clinical Research and specific challenge topic 04-HL-102: Develop Integrative Strategies to Elucidate the Mechanisms of Lung Diseases. Pulmonary arterial hypertension (PAH) is a syndrome
IMPAIRED MITOCHONDRIAL FUSION IN PULMONARY ARTERIAL HYPERTENSION
This application addresses the broad Challenge Area (01) Behavior, Behavioral Change, and Prevention and specific Challenge Area 01-HL-101: Develop innovative technologies and measurements to assess and provide real-time feedback on behavioral
Advancing Physical Activity Measurement using Pattern Recognition Techniques
The Broad Challenge Area addressed in this proposal is (03) Biomarker Discovery and Validation, and the Specific Challenge Topic is 03-HL-101. The purpose of this proposal is to improve the accurate and early diagnosis of idiopathic interstitia
Peripheral Blood Biomarkers for Idiopathic Interstitial Pneumonia
This application addresses broad Challenge Area (05) Comparative Effectiveness Research and Specific Challenge Topic 05-MD105, Health Literacy. After examining feasibility, this intervention compares the use of a patient advocate to promote eff
A Patient Advocate and Literacy-Based Treatment of Asthma
There is currently no sensitive noninvasive method for diagnosing preclinical peripheral arterial disease (PAD), which affects 8 million Americans. In this project we propose to implement and evaluate a new noninvasive MRI-based method in healt
Integrated MRI-Based Examination for Evaluation of Peripheral Arterial Disease
This application addresses broad Challenge Area (03) Biomarker Discovery and Validation and specific Challenge Topic, 03-HL-101: Identify and Validate Clinically Relevant, Quantifiable Biomarkers of Diagnostic and Therapeutic Responses for Bloo
Proteome and Transcriptome Markers of Hypertension in Urine and Plasma Exosomes
This application addresses broad Challenge Area (04) Clinical Research and specific Challenge Topic, 04-HL-101: Identify Mechanisms Linking Cardiopulmonary Disease Risk and Sleep-Disordered Breathing. Diabetes is increasing in epidemic proporti
EFFECTIVE TREATMENT OF SLEEP APNEA IN PREDIABETES TO REDUCE CARDIOMETABOLIC RISK
This application addresses broad Challenge Area (11): Regenerative Medicine and specific Challenge Topic, 11-HL-101: Develop cell-based therapies for cardiovascular, lung, and blood diseases. Sudden cardiac death (SCD) due to myocardial infarct
Targeted Cell Therapy for the Treatment of Venticular Tachycardia
This application is in response to RFA-09-09-003 and addresses broad Challenge Area (15) Translational Science and specific Challenge Topic, 15-OD(ORDR)-101: Pilot Projects for Prevention, Early Detection, and Treatment of Rare Diseases. The co
Screening for Jervell and Lange-Nielsen Syndrome
Atrial fibrillation (AF) is the most common cardiac arrhythmia affecting over 2.5 million Americans at a cost of over 7 billion dollars per year to Medicare alone.  Importantly, 15% of all strokes are attributed to atrial fibrillation with the
Minimally Invasive Surgical Pulmonary Vein Insolation vs. Medical Management in P?.
RECOVERY ACT - EDWARD BYRNE MEMORIAL JUSTICE ASSISTANCE GRANT (JAG) PROGRAM / GRANTS TO UNITS OF LOCAL GOVERNMENT
RECOVERY ACT - EDWARD BYRNE MEMORIAL JUSTICE ASSISTANCE GRANT
Beginning September 9, 2009, funding provided by the BJA FY 2009 Recovery Act-Edward Byrne Memorial Grant, is being used to pay for salaries/benefits of two part time positions which had been eliminated from the city's budget as of August 31, 2
Cottage Grove Police Dept. 2009 Byrne Grant-P.T. Salary/Benefit for eliminated positions
This grant program is authorized by the American Recovery and Reinvestment Act of 2009 and by 42 U.S.C. 3751(a).  The stated purposes of the Recover Act are to preserve and create job and promote economic recovery; to assist those most impacted
The American Recovery and Reinvestment Act of 2009
Lincoln County Sheriff's Office Emergency Operations response Grant
units and will be available for use at the scene of a crisis.
Equipment, supplies and technology acquistion.
City of Miami Gardens Police Department Enhanced Deployment Operation
FY2009 Recovery Act JAG Program - Purchase and installation of digital  video systems in 10 sheriff's patrol cars.
The Police Department's goal is to re-establish the Citizens Police Academy, restore the Cops and Kids Basketball Program, provide educational programs for Neighborhood Safety and Senior Citizens Crime Prevention, and Summertime Traffic Enforce
Town of Lincoln:  2009 Byrne/JAG ARRA Direct Award for Crime Prevention and Education Programs and Police Equipment Purchase
Equipment Acquisition for Law Enforcement Agencies.
Equipment Acquisition for Law Enforcement Agencies
To improve communications and other operational capabilities of both the prime and sub recipients.
SBPD and HCSO Agency Improvements Program
The Lincoln Police Department, Lincoln/Lancaster County Communications Center (911) and Lancaster County Sheriff's Office have come together on a plan to enhance public and officer safety. This will be done by purchasing computer equipment, sof
Lincoln County Sheriff’s Department is trying to create an Officer Information Improvement Program to help us keep our deputies in the field on patrol. The  first defense to preventing crime in our community is visibility. This grant will all
The County of Greenwood will use its FY2009 Recovery Act JAG award to boost its crime reduction and prevention strategy.  The funds will be used by the Sheriff's Office to purchase three patrol cars, a canine, communications equipment, cameras
This cities of Brownsville, Harlingen, Port Isabel, and San Benito, County of Brownsville, and the Town of South Padre Island are in a disparate arrangement and will share the Recovery Act JAg award.  The Brownsville Police Department will serv
Recovery Act Equipment and Personnel Enhancement
The city of Indio, in conjunction with the Indio Police Department (IPD), will utilize its 2009 Recovery Act Justice Assistance Grant (JAG) funds to purchase assorted safety equipment, surveillance equipment, telephone recording equipment, and
Recovery Act: Edward Byrned Memorial Justice Assistance Program
Prevention and investigation of crimes in Tuolumne County.
Prevention and investigation of crimes in Tuolumne County
To improve Datalux, an integrated mobile public safety system for police vehicles. This system provides officers access to Atwater Police Department's record management system, DMV records, and other online data systems.
The Recovery Act will inject $787 billion into the economy, providing jobs and much needed resources for states and lcoal communities. Among these resources is more than $4 billion for state and local law enforcement and other criminal and juve
Taney County Emergency Communication Project
Project will fund half of the Southwest County Youth Court Program.  Goals will be to review at least 8 youth court cases a quarter, fund at least 65 overtime hours for youth patrol a quarter, and to mitigate a minimum of 33 juvenile criminal c
The Marion County Sheriff's Office completed the tasks implemented by this grant.  We purchased a new 2010 Crown Vic, had it painted and detailed thus adding another patrol car in the community.  We purchased and installed laptop computers and
Hudson County Justice Assistance Grant- American Recovery and Reinvestment Act of 2009. The City of Bayonne, Town of Guttenberg, Town of Harrison, City of Hoboken, City of Jersey City, Town of Kearny, Township of North Bergen, Town of Secaucus,
Hudson County Justice Assistance Grant - American Recovery Act
Acquisition of standard law enforcement and tactical equipment to control, detect, or investigate crime or to prosecute criminals.
This grant will be used to purchase equipment to enhance police services, increase efficiency, reduce crime, and enhance community-oriented policing.  The purchase of supplies and equipment will also contribute to the economy, including the mot
Law Enforcement Improvements and Equipment Projects
K-9 $11,948; Interview Equipment $21,424; Substation Furniture $25,000; Uniforms $13,570
BJA FY 09 Recovery Act Edward Byrne Memorial Justice Assistance Grant Program
BSB LED Technology, Integration and Equipment Project
This grant was used to fund a portion of the total cost of a new public safety software system for the Manassas Police Department.  The current system is antiquated and inefficient, and it is anticipated that the new integrated software solutio
The Town of Christiansburg will use the recovery act JAG Funds (28411) to purchase a video surveillance equipment for our vice division and lights for hte patrol fifles.  The equipment is considered essential to enhancing officer and community
The City of Hemet will utilize the 2009 Recovery Act JAG award for the Hemet Public Safety Data Management System Upgrade.  The purpose of the project is to upgrade the Hemet Police Department's (HPD) computer-based dispatch, records management
Public Safety Data Management System Upgrade
City of Victoria Police Department In Car Video Replacement Project
City of Victoria Police Department In Car Video repalcement Project
Purchase equipment such as in-car video camera system, unmarked police cruiser, net motion,  token server, license plate reader/software, evidence software, ballistic shield, prtable radios, tasers, & ballistic blankets & narcotics detection do
Upgrade technolgy for District, Circuit and Probate Courts which will enhance service to the public.
The City of San Angelo and Tom Green County are listed as disparate jurisdictions on the Recovery Act JAG local allocation list.  The city will serve as the fiscal agent to adminster the grant funds for both jurisdictions.  Each entity will use
Fourteen communities within Plymouth County will fund projects which improve the effectiveness and efficiency of their criminal justice systems, processes and procedures.  Specifically, Abington will upgrade their police radio system; Bridgewat
2009 Edward Byrne Memorial Justice Assistance Grant
software and air card service for MDT in cars
BJA FY09 Recovery Act Edward Byrne Memorial Justice Assistance Grant funds are for Personnel and Equipment costs by 17 local municipal sub-recipient police departments. Funds will be used to purchase various types of equipment to help law enfor
BJA FY09 Recovery Act Edward Byrne Memorial Justice Assistance Grant
Salisbury - Rowan Law Enforcement Technology and Equipment Upgrade
The Hot Springs Police Department will use its share of the award ($290,823) to fund six programs.  The goals of each program will be to utilize the Recovery JAG funding to incorporate law enforcement technology. The Hot Springs Police Departme
The City of Hot Springs and Garland County will utilize the JAG Recovery Grant to purchase law enforcement related equipment and training opportunities.
With the recent down turn in the economy, many local governments are tightening their budgets.  As communities pay for the necessities, there may not be enough revenue to purchase additional needed items or to replace well worn pieces of equipm
Inmate tracking and victim notification systems
Inmate Tracking & victim notification systems
every department involved under this grant have met their goals so far. numerous amount of equipment have been purchased by departments making officer jobs easier to perform and making it safer for each officer. the anticipated outcomes are tha
The Recovery Act Justice Assistance Grant is a formula grant awarded by the Department of Justice under ARRA and is a JOINT AWARD to 35 Local Jurisdictions.  Allegheny County PA is the Prime Recipient and the 34 other Awardees are Sub-Recipient
Recovery Act Justice Assistance Grant to Allegheny County and 34 Municipalities in Pennsylvania
The Currituck County Sheriff's Office purchased 6 in car DVD Video Recorders.
In-Car DVD Video Recorder Implementation
The city of Bakersfield will use the Recovery Act JAG funds to support the Bakersfield Police Department's Stabilization and Restoration Project. This project will make street officers more available and equipped to proactively address the imme
BAKERSFIELD POLICE DEPARTMENT SABILIZATION AND RESTORATION PROJECT
JAG Grant for the purchase of police equipment for Hardin County Sheriff's Office, Elizabethtown Police Department and Radcliff Police Department
Will purchase 1 or 2 Crown Vicoria Patrol cars
Enhancing Law Enforcement - purchase of equipment and training.  Tooele City will purchase a forensic digital imaging system and supplies to implement the system, as well as pay for training for officers to operate the system.  This system will
Enhancing Law Enforcement in Tooele County, UT
Grant to replace radio equipment and vehicles.
The City of Hattiesburg will act as fiscal agent for USDOJ Byrne JAG including drawing down funds that will be divided as follows: Forrest County - $89,593.60; City of Petal $11,287.00; City of Hattiesburg - $134,390.40. Hattiesburg will use th
2009 Byrne Justice Assistance Grant ARRA Funding
Special emphasis patrol and weapons upgrade
The Justice Assistance Grant (JAG) Program funded under the Recovery Act is the primary provider of federal justice funding to state and local jurisdictions. Recovery JAG funds support all components of the criminal justice system, from multi-j
City in-car video systems and county criminal investigator and deputy equipment.
In-car video/criminal investigator and deputy equipment
DOJ Disparate funds for CRPD/MRPD/LCSO All agencies are intending to use their portion of the grant funds for equipment purchases. These equipment purchases by all the agencies will be upgrades to current equipment or additional equipment to he
This project is for purchasing of video equipment in police cars and a system for forensic and evidence tracking.
The grant will address the specific problem of insufficient capacity to recruit, train, and match qualified mentors with at risk middle school youth in Racine and Kenosha Counties
The Center for Creative Leadership (CCL) with the Greensboro, NC YMCA will expand a high-impact, research-based youth mentoring leadership program throughout the Greensboro YMCA area (Guilford & Rockingham counties, combined population 560,000)
Expanded YMCA Black and Hispanic Achievers Mentoring Program to Reduce Risk Behaviors
OJJDP FY09 Recovery Act Local Youth Mentoring Initiative
Urban Ventures Youth Mentoring and Employment Project
VOLUNTEERS OF AMERICA WESTERN WASHINGTON
Mentoring Children of Promise (MCP) provides mentoring services to youth, ages 7-18, with parents involved in the criminal justice system living in Snohomish and King Counties. Program objectives include providing quality mentoring to 70 youth
The Ventura County District Attorney's Office's major focus under this Reducing Mortgage Fraud and Crime Related to Vacant Properties/Mortgage Fraud Investigation and Prosecution Program (Program) is to expand our ability to investigate and pro
Reducing Mortgage Fraud and Crime Related to Vacant Properties/Mortgage Fraud Investigation and Prosecution Program
Multi-Agency U.S.-Mexico Project to reduce crime and violence in California. The goal of the project is to reduce crime and violence along the U.S.-Mexico border in California by facilitating cross-agency information sharing and collaboration a
Multi-Agency U.S. Mexico Border Project to Reduce Crime and Violence in California
BIG BROTHERS BIG SISTERS ASSOCIATION OF CENTRAL OHIO
This grant program is authorized by the American Recovery and Reinvestment Act of 2009 (Public Law 111-5) (the Recovery Act).  Office of Juvenile Justice and Delinquency Prevention made awards to support local organizations that develop, implem
Retain 1 Community Service Officer (CSO) to respond to calls for police service; retain 1 Dispatcher to dispatch calls for police service.
Hiring of two civilian Services Officers and conversion of the Court Liaison Officer and Training Officer from sworn to civilian positions, thereby returning two sworn Police Officers to field patrol duty.
Each of the entities have entered into a memorandum of understanding to use the funds awarded to purchase needed equipment and/or hire,retain,and train personnel to further their mission of providing basic Law Enforcement to their communities.
Support of Law Enforcement to prevent, and reduce crime and violence,with personnel and equipment.
To purchase much needed equipment for our department. To be able to utilize said equipment in the saving of lives throughout our county and to insure interoperability with surrounding jurisdictions.
This award allowed us to purchase equipment for the Enterprise Police Department, The Coffee County Sheriff's Office and the Elba Police Department
2009 JAG Coffee County Enhancement Program
The Police Department is continuously experiencing a heavy demand on its ability to continually deliver quality service; this is directly related to the growth of the City.   According to the 2008 FBI Uniform Crime Report, cities in the South a
The purpose and overall objective of the grant is to provide updated equipment and technolgy to meet the needs of the Law Enforcement Agency in which will provide for many items including Glock Handguns, Tasers, Outer Armor Vest Covers and Patc
Technology and Equipment Replacement Grant
upgrades to Sheriff's Dispatch and Upgrades to the City of Florence K-9 Unit and Downtown Security.  upgrades to Sheriff's Dispatch include converting to a CAD system.  Upgrades to the K-9 Unit include the purchase of two canines and officer tr
Upgrades to Sheriff's Dispatch and Upgrades to City of Florence K-9 Unit and Downtown Security
FY 2009 Recovery Act Justice Assistance Grant Program.  Patrol Car Camera Installation Program.
The City of Colorado Springs and El Paso County are requested funding from the Edward Byrne Memorial Justice Assistance Grant (JAG) for the Advancing Policing through Technological Efficiency and Alternative Response Project.    The projects fu
Advancing Policing through Technological Efficiency and Critical Resources and Alternate Response Project
The award has been utilized to enhance video recording and clarification capabilities.
Updating and Enhancing Recording Systems
The goal of this project is to prevent or reduce crime through proactive policing.  This will enhance the ability of officers to perform therir duties more safely and effectively, increase the efficiency of the departments, provide necessary tr
Duluth Police Department JAG Local Grant for Five Jurisdictions
The purpose of the Recovery Act is to preserve and create jobs and promote economic recovery. The ARRA Edward Byrne Memorial Justice Assistance Grant (JAG) Program is the primary provider of federal criminal justice funding and supports all com
The City of South Lake Tahoe purchased unmarked police vehicles to assist in combatting crime; particularly gang related criminal activity inside the city limits.
Skagit County Victim Offender Reconciliation Program for juvenile offenders
Skagit County Victim Offender Reconciliation Program
The vision for this program will cover nearly every aspect of criminal activity from crimes against the government, white collar crimes, child sex abuse and will even encompas our community caretaking function.  This program requires extensive
Kern County is allocating the award equally to four departments: District Attorney, Public Defender, Probation, and Sheriff.  The PD will retain one full time Public Defender.  Probation will retain one Probation Officer III and has acquired a
FY 09-10 RECOVERY ACT EDWARD BRYNE MEMORIAL ASSISTANCE GRANT PROGRAM LOCAL SOLICITATION
BJA FY09 Recovery Act Wdward Byrne Memorial JAG Program - Local Solicitation.  Police In-Car Video Camera System
Henderson County FY 2009 Recovery Act Justice Assistance Grant Program
Marysville Police Department Technology Improvement Program will improve the delivery of police services by the Marysville Police Department through the purchase/replacement of items of technology used by the Department to deliver police servic
Marysville Police Department Technology Improvement Program
Marked Emergency Vehicle Replacement Project
Jag stimulus funding engages a partnership between the City of Buffalo and 11 suburban law enforcement partners focusing on crime reduction through job creation/preservation; purchasing equipment and technology and community initiatives that pr
The Jonesboro Police Department was awarded federal funding the amount of $281,390 to secure much needed personnel as provided within the score of this grant program.  PROJECT IDENTIFY is the name of the program identified in this application w
EPD Crime Prevention/Park Monitoring Program
This grant is for the purchase of equipment under the 2009 Recovery Act JAG grant funding.
The disparate jurisdiction consisting of the city of Ottumwa and Wapello County will use their Recovery Act JAG award to purchase law enforcement equipment.
The Conasauga Drug Court Program was started in February of 2002 by Judge Jack Partain and is a 24 month, post-plea program that was designed around the ten key components of drug courts developed by the National Association of Drug Court Profe
Records Management System Updates and Evidence Preservation Improvements
Purchase upgraded tasers for the jpolice officers of the Oviedo Police Department.
Oviedo Police Department Taser Upgrade Project
Placer County Recovery Act JAG project/Task force and Roseville PD Community Services Officers
Implement security changes at the Granville County Courthouse.
Grant awarded for the purchase of Law Enforcement equipment in order to enhance our law enforcement service delivery within our jurisdiction
Funding was used to purchase police cruisers.
The City of Wilson and the County of Wilson in North Carolina are submitting a joint application based upon being declared a disparate jurisdiction. Both governmental entities have agreed to allow the City of Wilson to serve as the fiscal agent
Ecite/MOVE Expansion in Patrol Cars for the Shelby County Sheriff's Office
JAG grant to purchase equipment for patrol deputys
Independence County Sheriffs Department JAG Grant
St. Mary's County Sheriff's Office Recovery and Reinvestment Act/Justice Assistance Grant 2009 (Edward Byrne Memorial Justice Assistance Grant (JAG) Formula Program (Local Solicitation) will be used to meet three main goals for St. Mary's Count
BJA FY09 Recovery Act Edward Bryne Memorial Justice
Purchase of license plate recognition cameras to assist in identifying stolen vehicles, vehicles involved in crimes, and outstanding warrants.
Funds are being utilized and shared between the County of Kauai, Office of the Prosecuting Attorney and the County of Kauai, Kauai Police Department for training and program purposes, equipment purchses, and to staff a 1.00 FTE Process Server.
Ansonia Police Department job retention through the use of an automated fingerprint identification system.
Rock County Sheriff's Office, Janesville Police Department, and Beloit Police Department Crime Suppression and Equipment Upgrade Program.  Purpose:  Adequately equip personnel to combat gang and narcotics related crimes.
Byrne Local Solicitation grant program for multi-agencies within Prince Georges County, Maryland to carry out crime prevention and control activities.
FY2009 Recovery Act Justice Assistance Grant
The Edward Byrne Memorial State and Local Law Enforcement Assistance Grant Program (Byrne Formula Grant Program) is a partnership among federal, state, and local governments to create safer communities.  BJA is authorized to award grants to sta
The Edward Bryne Memorial Justice Assistance Grant is the primary provider of federal criminal justice funding to support all components of the criminal justice system and funds needed projects that may address crime.  The Moultrie Police Depar
The U. S. Department of Justice is providing funds to prevent and reduce crime in the City of Fairbanks.  The City of Fairbanks is using the funds to retain an officer and purchase equipment.
ABADE & Tactical Team Operational Support
Lewis County Sheriff's Office  intends to purchase  one fully outfitted marked patrol car, equipped with an in-car video system.  The equipped vehicle is to be used by sworn officers of the Sheriff's Office with the intent to provide the necess
Lewis County Recovery Act Justice Assistance Grant Program
Purpose of this grant is to increase the security for staff and citizens by enhancing the key card access, video camera system and integrating alarms into one system for the police department.  This project will allow video recording of subject
The growing population in Douglas County will further increase the number of misdemeanor and felony criminal arrests by the Douglas County Sheriffs office. Thereby the number of cases handled by the Douglas County District Attorneys Office and
ARRA JAG Douglas County Technology Improvements
This is a grant formula award award program.  The Edward Byrne Memorial Justice Assistance Grant (JAG) Program-Local is the primary provider of federal criminal justice funding to local jurisdictions.   This formula grant program is authorized
Public Safety, Disaster Preparedness & Relief
The Recovery Act Edward Byrne Memorial Justice Assistance Grant will be used to improve the services provided and capabilities of the law enforcement agencies serving the citizens of Scioto County, Ohio.  The Scioto County Sheriff's Office and
FY09 Recovery Act BJA Edward Byrne Memorial Justice Assistance Grant- Retaining Law Enforcement Personnel and Information Systems Upgrade
FY 2009 Recovery Act JAG Program -- Police Department technology improvement
Program Abstract  Whitfield County Sheriff?s Office Purchase of Law Enforcement Equipment   Whitfield County Georgia consists of an area of 291 square miles and serves a population of approximately 100,000 individuals. The Whitfield County Sher
2009 JAG Recovery Act Grant Project - Conasauga Drug Court
The money is being used to purchase new laptops for our field personnel in the completion of mandatory reports.
ENHANCE SAFETY AND INVESTIGATIVE ABILITY OF POLICE FORCE
The funds for this Grant have been spent.  There was no activity during this reporting period.
School Resource Officer Salary Assistance
Bay Minette PD eCitation Equipment Grant to purchase computer-based traffic citation writing equipment and software to be installed in police vehicles for the purpose of enforcing traffic laws and aiding in criminal investigations for the purpo
Bay Minette City Recovery Act Justice Assistance Grant Program
City of Williamsburg Recovery Act Justice Assistance Grant Program.
PLANNING EVALUATION AND TECHNOLOGY IMPROVEMENT PROGRAMS.
PLANNING EVALUATION AND TECHNOLOGY IMPROVEMENT PROGRAMS
Purchase Police equipment; supplies for Graffiti Management Program; Street level Drug Interdiction Program; Street Outreach Program
The City of Levelland Police Department received funds from the U.S. Department of Justice, Office of Justice Programs, Bureau of Justice Assistance in the amount of $32,212 through the American Recovery and Reinvestment Act of 2009.  The Level
Purchase new radio communication system and enhance existing repeater.
Purchase new radio equipment and enhance existing repeater.
Retain/create nine (9) Yolo County law enforcement/judicial positions with Recovery Act funding (preserving jobs). Maintain responsible custody of a minimum of 1,000 defendants in the first year by minimizing risks associated with their release
FY 09 Recovery Act Edward Byrne Memorial Competitive Grant Program: Providing funding of Neighborhood Probation and Parole Officers
The Recovery Act Edward Byrne Memorial Competitive Grant Program (Byrne Competitive Program) will help communities improve the capacity of state and local justice systems and provide for national support efforts including training and technical
African Immigrant Muslim Community Outreach Program (AIMCOP)
The title of this award is Enhanced Supervision and Community Re-integration. The purpose of Probation is risk management, a strategy designed to reduce an offender's future criminal conduct. This strategy consists of risk control, the limitati
Edward Byrne Memorial Competitive Grant Program - Probation Supervision and Community Reintegration
This grant will be used to establish a statewide Mortgage Fraud Task Force.  The grant will fund one full time prosecutor and one full time special agent.
Oregon Mortgage and Foreclosure Task Force
BJA FY 09 Recovery Act Edward Byrne Memorial Competitive Grant Program: Hiring of Civilian Law Enforcement (Support Personnel)
OKMULGEE COUNTY FAMILY RESOURCE CENTER INC
The grant provides the 2 year salary and benefits for a FTE (CASA Volunteer Coordinator) to recruit, train and retain CASA volunteer advocates in Creek County, Oklahoma. The grant award will be used to support the Creek County CASA program to i
Creek County CASA (Court Appointed Special Advocates Program
ILLINOIS COALITION AGAINST SEXUAL ASSAULT
The Illinois Coalition Against Sexual Assault (ICASA) is using the grant funds to preserve and create sexual violence counseling and advocacy positions over an 18-month period. ICASA, which has subcontracted and monitored funds to local crisis
Improving Resources and Services  for Victims of Crime
The specific programmatic goals in this proposal include: 1) developing a data-driven interagency approach to crime problems in Bexar County, centered on a partnership with the local University 2) building capacity for generating crime analysts
Crime Analysis Consortium (CAC): Building Capacity in Bexar County, Texas
Creation of Court Compliance Officer Position for the Apache Junction Municipal Court
Problems Solving Courts Administration Project
Fund two full-time positions in the Police Crime Laboratory tasked with assisting an existing staff member in accepting, cataloging, and inventoring evidence at the Laboratory's front counter and with the forthcoming conversion to a bar-coding
Consolidation of Forensic Evidence Processing
Seventh Judicial District Department of Correctional Services Field Office Offender Reentry Services Enhancement Project
Offender Reentry Services Enhancement Project
field for this final report is representative of  656,375.90 ARRA 2009-compensated hours that Boys & Girls Clubs of America (BGCA) received from sub-grantee local Boys & Girls Clubs, and subsequently converted to the 1262.26 jobs created and r
Boys & Girls Clubs Recovery Act National Mentoring Programs
Hire an experienced criminal investigator to construct a criminal intelligence data base and enhance information sharing capabilities including technology and training expenses needed by the investigator. Funds will also be used for leadership
Mendocino County Public Safety Computer Software Update/Replacement Initiative.
Mendocino County Public Safety Computer Software Update/Replacement Initiative
Law Enforcement- Combating Rural Crime. This grant award is to have deputies work Interstate-15 doing Drug and Criminal interdiction.  The deputies will work with local agencies in combating rural crime. Our goal is to arrest those suspect that
Trenton Police Department School Resource Officer Program
CITY OF ALMA DEPARTMENT OF PUBLIC SAFETY
The Alma Department of Public Safety will use the grant funds to implement a drug and crime enforcement initiative. The department plans to implement a police K-9 unit and become actively involved with the area multijurisdictional drug enforcem
Alma Police Department Drug and Crime Enforcement Initiative
Navajo County will use its award to hire a Criminal Analyst/Investigator for the Navajo County Attorney's Office. Navajo County does not have a central depository for criminal case information to be collected, stored, analyzed, and shared. The
BJA FY 2009 Recovery Act Assistance to Rural Law Enforcement to Combat Crime and Drugs: Facilitating Rural Justice Information Sharing
Emmet County Sheriff's Office Prescription Drug Diversion Unit, consisting of one detective assigned to educate and inform the public and medical professionals of the abuse and enforce the law as it relates to the drug diversion problem.
Emmet County Sheriff's Office Prescription Drug Diversion Unit
This project will assist the Toledo Police Department in preventing and combating crime in our jurisdiction and neighboring rural areas by establishing Information Sharing and Intelligence-led Policing strategies.   The program will take advant
Assistance to Rural Law Enforcement to Combat Crime and Drugs:  Facilitating Rural Justice Information Sharing.
Rural Law Enforcement assistance grant.  Designed to help rural law enforcement agencies with investigations, with a focus on drug enforcement
Del Norte County Sheriff's Office Investigations Augmentation Project
Ozark County will use its grant in the amount of $127850.00 to hire an Ozark County Sheriffs' Departmeent Drug Task Force Investigator and to purchase a surveillance vehicle to assist in investigating drug related crimes in rural areas of the c
2 full time correction officers would be hired to provide staffing levels that enhance the safety of the correction staff and inmates, allow for expedited processing of new arrestees, and provide a more timely classification and housing unit pl
CCT Improving Prescription Drug Abuse Investigation and Prevention Project
Retention of 3 Sheriff's Deputies, 1 Corrections Officer and 1 Community Service Officer
The ultimate goal of this project is two-fold, to promote economic recovery to the local communities and to prevent and combat crime within the Squaxin Island and Mason County communities. Funds awarded throught DOJ Recovery Act: Assistance to
Squaxin Island Tribe Combating Crime 2009
Douglas County, along with Douglas County Juvenile Department, will use its award for the Intensive Intervention Program (IIP). Douglas County will reduce chronic recidivism by identifying youth who are most likely to re-offend, and by utilizin
Douglas County Juvenile Department Intensive Intervention Program
Under Category 4, the St. Landry Parish Sheriff's Office will use its award to enhance the collection and sharing of criminal justice information.
As stated in the application, the overall goal is to eradicate drugs from Allen County by hiring additional personnel and improving the Sheriff?s Department rural law enforcement investigations regarding illegal clandestine drug operations. Thi
Operation 'Screening for Success' will create the following four (4) jobs in the Montezuma County Detention Center.  One (1) Nurse, One (1) Screening Program Manager and Two (2) Detention Deputies that will specialize in screening inmates.  The
This grant was awarded to retain 2 deputies to patrol two townships(Pleasant and Miami) which have a high crime rate.  The goal was to decrease crime and increase arrests in these townships.
The goal of the DNA program is to get all laid off personnel back into their regular paid working positions with the capability to sustain these positions and also to get public safety restored to what it was before employee lay offs Reducing t
Eliminate drug and gang violence by launching community-oriented policing model in rural setting
STRATEGIC APPLICATIONS FOR SOCIETY L.L.C.
The goals of this project include addressing the unique challenges of rural jurisdictions to: 1) interdict illegal drugs and drug manufacturing/drug distribution networks in collaboration with local, tribal, state, and federal law enforcement a
Recovery Act Rural Law Enforcement Training and Technical Assistance Project
Provide Crime Victim Compensation to eligible crime victims and  to medical/service providers who have treated eligible crime victims.
ARRA VOCA Victim Compensation Formula Grant
The purpose of this grant is to assist persons who are innocent victims of violent crime.  Payments made under the Criminal Injury Compensation program are intended to defray the costs of medical services, loss of earnings, burial costs, and ot
JUDICIARY COURTS OF THE STATE OF INDIANA
Funds support the provision of crucial financial assistance and compensation to victims and survivors of crime.
Recovery Act - OVC FY2009 Victims Compensation Forumla Grant
The Recovery Act - OVC FY 09 VOCA Victim Compensation Formula Grant provides continued financial assistance to victims of violent crime.
Recovery Act - OVC FY 09 VOCA Victim Compensation Formula Grant Program
VOCA Recovery Act funds are being used for payments to victims of crime through the victim's compensation program.
Recovery Act-OVC FY09 VOCA Victims Compensation Formula Grant Program
This award provides a method of compensating and assisting those persons who are innocent victims of criminal acts and who suffer bodily injury or death by providing financial assistance to victims of crime and their family members.
Recovery Act - OVC FY 09 VOCA Victim Compensation Formula Grant
CORRECTIONS AND REHABILITATION, NORTH DAKOTA DEPART OF
Provide compensation for victims of violent crime in North Dakota, or residents of North Dakota injured in a violent crime outside the state where a compensation program does not exist.  Benefits may include medical expenses, lost wages, or in
Recovery Act OVC FY09 VOCA -Victim Compensation Formula Grant Program (CVC)
The overarching purpose of all VOCA Recovery Act sub-grants is to hire/retain direct crime victim services personnel who respond to the needs of domestic violence, sexual assault, child abuse and underserved victims.
Recovery Act - OVC FY09 VOCA Assistance Formula Grant Program
The Recovery Act – OVC FY 09 VOCA Victim Assistance Formula Grant Program supports the provision of services to victims of crime within the State of Texas. Furthermore, these funds are used to enhance direct services that respond to victims
Recovery Act - OVC FY 09 VOCA Victim Assistance Formula Grant
This funding has allowed direct service providers throughout new Hampshire to preserve at least an estimated 14 full time equivalent (FTE) positions.  The estimate of 14 (FTE) positions reflects information provided by current VOCA sub-grantees
Recovery Act - OVC FY 2009 VOCA Victim Assistance Formula Grant Program
The Law Enforcement Planning Commission (LEPC) through the Department of Justice Programs (DOJ)- Office for Victims of Crime (OVC) FY'09 Recovery Act Victims of Crime Assistance (VOCA) Grant  Program has been awarded grant funding in the amount
Recovery Act-OVC FY09 VOCA Victim Asisstance Formula Grant Program
VOCA - provide funding and support to organizations which provide direct services to victims of crime
FY 09 Recovery Act - Victims of Crime Act (VOCA) Victim Assistance Formula Grant Program
Other Individual and Family Services  These funds were used to expand direct services to victims of crime. One particular area was the Intimate Violence Enhanced Services Team (InVEST) program, which is specially designed to provide intensive s
FY 09 Recovery Act - Victims of Crime Act (VOCA) Assistance Formula Grant Program
ILLINOIS CRIMINAL JUSTICE INFORMATION AUTHORITY
The purpose of Victims of Crime Act victim assistance formula grant is to support the provision of services to victims of crime throughout the Nation. Services under this grant program are defined as those efforts that (1) respond to the emotio
Recovery Act - OVC FY09 VOCA Victim Assistance Formula Grant Program
The S.C. ICAC Task Force is utilizing stimulus funds to address the long-standing goal of preventing and reducing the online victimization of children. We are doing this by creating two new jobs, retaining one and partially funding three others
WI ICAC Task Force  Through this project, the Wisconsin Department of Justice, Division of Criminal Investigation and Wisconsin Internet Crimes Against Children (WI ICAC) agencies will continue to offer support to Wisconsin and other law enforc
This project seeks to enhance the Northern Virginia - District of Columbia Internet Crimes Against Children Task Force's efforts in fighting internet crimes against children, by increasing available investigative resources.  Three new full time
The County of Bedford (VA) sheriff's Office ($681,572) will use ARRA grant funds to support 3 Investigators and 1 Analyst and to pay overtime for officers working on ICAC cases.  This Task Force will also make subgrants to 7 local sheriff's off
Recovery Act Internet Crimes Against Children Task Force
This award will be used to fund two special agents to supplement the existing Oregon ICAC task force.    The grant will also fund training and travel for ICAC task force members and affiliates from participating agencies.
This ARRA grant will allow the Ohio Internet Crimes Against Children Task Force to increase its dedicated staff from 5 (which was its 2008 staffing level).   The Recovery Act has allowed the Ohio Task Force to add 2 additional employees with mo
The Ohio ICAC Task Force Expansion Project
The Internet Crimes Against Children (ICAC) Task Force Program seeks to maintain and expand State and regional ICAC task forces to address technology-facilitated child exploitation.  These task forces work collaboratively as a national network
OJJDP FY 09 RECOVERY ACT INTERNET CRIMES AGAINST CHILDREN TASK FORCE PROGRAM GRANT
The Polk County Sheriff's Office (FL) ICAC Task Force will use ARRA grant funds to create 2 new Computer Forensic Specialists positions for support operations of ICAC related investigations.  In addition, grant funds will also be used to make s
This grant program is funded by the American Recovery and Reinvestment Act of 2009 (Public Law 111-5) (the Recovery Act) and authorized by 42 U.S.C. 3751(a).  The stated purpose of the Recovery Act are to preserve and create jobs and promote ec
FY09 Recovery Act Internet Crimes Against Children Task Force Program
The Supporting Heroes in mental health Training (SHIFT) program aims to reduce the traumatic effects of viewing child sexual abuse images.  Primarily, it has developed a 3-hour psychoeducational training for law enforcement and other profession
Supporting Heroes In mental health Training (SHIFT)
Education and resources for judges on technology-assisted crimes against children.  The National Center for Justice and the Rule of Law will conduct conferences and online training for judges on legal aspects of technology-assisted crimes again
Education and Resources for Judges on Technology-Assisted Crimes Against Children
This is a  two-phase program  to address Law-Enforcement's need to automatically and remotely monitor environments such as prisons, schools and public parks. The goal is to increase the situational awareness in law-enforcement and correctional
Advanced Behavior Recognition in Crowded Environments
Project Description: US-LATT is a tool which provides forensic field investigators with the ability to quickly triage a computer system without the need for advanced training.
USB Live Acquisition and Triage Tool (US-LATT)
Emerging information on the safety of conducted electrical weapons (CEWs) has been reassuring, but this information must be placed into context with the injury risks of other less lethal force options available to law enforcement agencies.  Off
Officer and Suspect Injuries Associated with Police Use of Force
The NIJ and the DOD have sponsored AKELA's development of an ultra-wide band radar system to produce an imaging sensor capable of both mapping the internal structure of a building, and locating personnel inside the structure. This capability pr
Through the Wall Standoff Detection and Tracking of Individuals
The goals and objectives of this project are as follows: 1. Improve the intelligence collection capability of the Triangle HIDTA in order to identify Mexican DTOs operating in its Area of Responsibility and in surrounding jurisdictions. 2. Succ
2009 Triangle HIDTA: Combating Criminal Narcotics Activity Stemming from the Southern Borders
Title:	South Texas Inter-local Drug Interdiction Effort (Robstown)  Proximity to Texas/Mexico Border:	Mexico border is 112 miles to west and 119 miles to south   Program Goal: Control, reduce, and/or prevent criminal narcotics activity, includi
South Texas Inter-local Drug Interdiction Effort
Tribal Lands Correctional Facilities Construction/Renovation
BJA FY 09 Recovery Act Correctional Facilities on Tribal Lands Program: Renovation of existing detention facilities
ECONOMIC AND COMMUNITY AFFAIRS, ALABAMA DEPARTMENT OF
The intended purpose of this program is to comply with the stated purposes of the American Recovery and Reinvestment Act of 2009. This program's primary goal is to preserve and create jobs, to promote economic recovery, and to assist those law
The main purpose of our award is to help create jobs and/or preserve jobs for criminal justice-related agencies such as the Supreme Court, the Department of Public Safety (DPS), the Department of Corrections (DOC), etc.
FY 2009 Norther Mariana Islands Recovery Act:: Edward Byrne Justice Assistance Grant (JAG) Formula Program
The California Emergency Management Agency will use Recovery JAG funds to support local level multi-jurisdictional task force programs
OFFICE OF POLICY AND MANAGEMENT, CONNECTICUT STATE OF
The State of Connecticut was awarded $12,479,843 in federal Justice Assistance Grant Recovery funds, which is a no-match grant with a 48-month grant period.  As mandated by federal program regulations, $4.3 million of these funds will be distri
BJA FY 09 Recovery Act Edward Byrne Memorial Justice Assistance Grant Program State Solicitation
Goals:  Goal 1:  Justice Assistance Grant Program Recovery Act funds will be utilized to support the planning and administration of the formula grant program.  Goal 2: Justice Assistance Grant Program Recovery Act funds will be utilized to supp
West Virginia Recovery Act: Justice Assistance Grant Program
The Mississippi Division of Public Safety Planning will utilize the Recovery Act JAG funds to curtail illegal drug activity and violent crime through the funding of multi-jurisdictional drug task force programs, community crime prevention progr
The Justice Assistance Grant (JAG) Program funded under the Recovery Act is the primary provider of federal criminal justice funding to state and local jurisdictions. Recovery JAG funds support all components of the criminal justice system, fro
ATTORNEY GENERAL, HAWAII DEPARTMENT OF THE
The grant allows state and local jurisdictions to improve the functioning of the criminal justice system by creating jobs, retaining jobs, and providing operational resources.  Projects to be funded include drug task forces which will report on
State of Hawaii FY-2009 Recovery Act Justice Assistance Grant (JAG) Program
The Minnesota Department of Public Safety (MN DPS) plans to use its FY 2009 American Recovery and Reinvestment Act Justice Assistance Grant (ARRA JAG) to address system-wide improvements in Minnesota’s criminal justice system. MN DPS is commi
NATIONAL CRIME PREVENTION COUNCIL, INC., THE
Serving Survivors of Homicide Victims During Cold Case Investigations. The goal of this Project was to create a Guide for developing a protocol on how law enforcement can best serve survivors of homicide victims during cold case investigations.
Serving Survivors of Homicide Victims During Cold Case Investigations
This project will increase awareness and training of the needs of child abuse and neglect (CAN) victims with disabilities through the nation through the delivery of modified and expanded curriculum and existing training DVDs. The purpose is to
Abused Kids with Disabilities: A National Training and Support Project
Highway Infrastructure Investment Grant: Available for Use in Any Area (Flexible) and Rural Areas with Population under 5K
Safety and Resurfacing from N. Corp Limits of Accident to to Bear Creek Bridge 1103700
This ARRA project is being implemented in order for the FWS and Dobson Ranch LLC to work together to restore habitat (approx. 1,710 acres) for the candidate lesser prairie-chicken and other grassland dependent species.
The award funds services to the Imperial National Wildlife Refuge from the Student Conservation Association's Conservation Intern (CI) program, which recruits and places qualified young people for environmental and conservation service projects
Habitat Management Intern - Imperial National Wildlife Refuge
Guardrail Hazard Elimination Projects (Safety)
Marion VA Police Department Technology and Equipment Project
The district will educate and assist rural residents and businesses through various business and technology workshops and training services, as well as provide technical assistance services that promote the expansion/recovery of hurricane-affec
Rural Business Enterprise Grant - Technical Assistance
SR 281 AVALON BLVD FROM N OF CSX R/R BRIDGE TO S OF COMMERCE ROAD
Community Facility Grant.  The funds will be used to purchase a sanitation truck.  Funds have been expended to purchase a sanitation truck.
Purchase coagulation analyzer in the amount of $10,000.00 under project number BE0010.
SR 5-US1 FROM MILE MARKER 121.32 TO MILE MARKER 124.18
PIONEER VALLEY CHINESE IMMERSION CHARTER SCHOOL
Pioneer Valley Chinese Immersion Charter School
Safety and Resurfacing MD 410 to Albion Road
Safety and Resurfacing Cindy Lane to Brightseat Road
Highway Infrastructure Investment Grant:  Rural Areas with Population under 5K
MILITARY AND VETERANS AFFAIRS, MICHIGAN DEPARTMENT OF
This award funds fire suppression in the McLiesh building at the Grand Rapids Home for Veterans.  The fire suppression project is necessary to meet life safety code requirements.  This is the last building of the Grand Rapids Veterans Home to r
Grand Rapids Home for Veterans McLiesh Building fire suppression system project and Nurse Call System project.
CHURCH AND MAIN STREETSCAPE ENHANCEMENT, V/ CANAJOHARIE
116th / 34th Ave NE Fish Passage Culvert
The assistance provided to the City of Peterson was to replace the existing obsolete treatment plant with a new activated sludge package plant with screening and grit removal systems in order to properly treat the community's wastewater.  The f
Interstate Bridge Painting Contract Route I-280, Contract No. 3
ASSOCIATED GENERAL CONTRACTORS OF KENTUCKY INC
The AGC of KY was awarded a National Clean Diesel Grant to fund a retrofit/repower and reduced idling program using DPF technology applied to construction company fleets in KY. The general purpose of the grant is to improve air quality.
ARB was awarded a National Clean Diesel Funding Assistance Program Grant to fund a repower project targeting switch (yard) locomotive in the South Coast Air Basin. The general purpose of the grant is to reduce diesel emissions and improve air q
Repower Eleven Older Switch (Yard) Locomotives to Operate in the South Coast Air Basin
Louisville Jefferson County Metro Government was awarded a SmartWay Clean Diesel Innovative Finance program grant to fund a retrofit/replacement innovative financing project targeting non-road diesel equipment in Louisville/Jefferson County, Ke
Fairfax County was awarded a Clean Diesel Emerging Technology Program Grant to fund a retrofit project targeting school buses in Fairfax County, VA. The general purpose of the grant is to reduce diesel emissions and improve air quality.
Retrofit with the Shadowood/Tinnerman TEC 2010 Exhaust Reform System
HARC was awarded a Naional Clean Diesel Funding Assistance Program Grant to fund a retrofit project targeting marine vessels.  The general purpose of the grant is to reduce diesel emissions and improve air quality.
The City of Irving, Texas was awarded a Clean Diesel Emerging Technology Program Grant to fund a retrofit or program targeting municipal refuse haulers in Irving, Texas. The general purpose of the grant is to reduce diesel emissions and improve
City of Irving Municipal On-Road Fleet Retrofit
Port of Tacoma was awarded a National Clean Diesel Funding Assistance Program Grant to fund a retrofit project targeting two ships that Berth at the Port of Tacoma. The general purpose of the grant is to reduce diesel emissions and improve air
ENVIRONMENTAL PROTECTION, MAINE DEPARTMENT OF
Maine Department of Environmental Protection was awarded a National Clean Diesel Funding Assistance Program Grant to retrofit 21 diesel non-road engines used in material handling operations and 11 on-highway dump trucks. Retrofit technologies b
Maine Department of Environmental Protection Clean Diesel Construction Project
THE PORT AUTHORITY OF NEW YORK & NEW JERSEY
The Port Authority was awarded a National Clean Diesel Funding Assistance Program Grant in order to fund the shore power installation of the Brooklyn Cruise Terminal. The general purpose of the grant is to reduce diesel emissions and improve ai
Brooklyn Cruise Terminal Shore Power Installation
MDE was awarded a National Clean Diesel Funding Assistance Program Grant to fund a retrofit program targeting school buses in Maryland. The general purpose of the grant is to reduce diesel emissions and improve air quality.
State of Maryland School Bus Grant Program
PORT AUTHORITY OF THE CITY OF SAINT PAUL
Environmental assessments at brownfield properties located in the City of City of Saint Paul, with special emphasis on the Phalen Corridor, the Great Northern Corridor and the University-Midway Corridor.  The Port Authority chose to focus the u
Community-wide Environmental Assessment Grant Cooperative Agreement
Environmental cleanup of hazardous-substances contamination at the former Minnehaha Lanes Site in Saint Paul, Minnesota.
Hazardous Substances Cleanup Grant - Minnehaha Lanes Site.
This award provides stimulus funding to the City of Battle Creek to be used to conduct community wide assessments at potential brownfield sites contaminated with petroleum substances. Specifically, the recipient will complete up to 12 Phase I E
Battle Creek Stimulus Brownfields Assessment Petroleum
Baraboo Brownfields Hazardous Substance Assessment 2
Baraboo Brownfields Hazardous Substance Assessment  2
IDA ORE PLANNING AND DEVELOPMENT ASSOCIATION INC
On August 31, 2009, the U.S. EPA awarded the Anaheim Redevelopment Agency (Agency) $450,000 in Brownfields RLF supplemental funding under the ARRA, for the site-specific remediation of hazardous substances at the Ross Park Expansion Site Remedi
The Anaheim Redevelopment Agency Brownfields Revolving Loan Fund Grant for the Ross Park Expansion Site Remediation
American Recovery and Reinvestment Act funds will be used by the Housing Authority of the City of Aiken to conduct a site-specific environmental assessment at the former Avondale Mills - Gregg Plant, which is potentially contaminated with hazar
Site-Specific Hazardous Substance Brownfields Assessment Project - former Avondale Mills - Gregg Plant
To conduct enviromental assessment activities at the brownfields properties located in the City of Durham, North Carolina.
Combined Hazardous Substance and Petroleum Community-wide Assessment
A Regional Approach to Assessment and Redevelopment of Brownfield Properties Contaminated by Hazardous Substances in Franklin County, Massachusetts.
Hazardous Substances Community Wide Assessment
Windham Regional Commission,  Petroleum Assessment Program
Community - wide Environmental Assessment Cooperative Agreement
MetroHartford Brownfields Assessment Grant-Petroleum.  Funds are to be used to conduct community-wide assessments at potential brownfield sites contaminated with petroleum substances.
Petroleum Community-Wide Environmental Assessment Cooperative Agreement
To conduct environmental site assessment activities at Brownfields properties located in Berkshire County, Massachusetts.
The purpose of the award is to conduct community-wide assessments at potential Brownfield sites contaminated with petroleum.
To conduct environmental assessment activities at brownfields properties located in the City of Bath, Maine.
Petroleum Community-Wide Environmental Assessments within the City of Bath, Maine
This grant will be used to provide cleanup of the applicable portion of the North Brookfield Downtown Development project.
14 South Common Street Brownfields Cleanup
To perform cleanup of hazardous substances at Lot 76 located in the Town of Howland, ME.
hazardous substances cleanup at Lot 76 located in the Town of Howland, ME.
HOUSING AND COMMUNITY AFFAIRS, VERMONT DEPT OF
Revolving Loan Fund for Vermont Agency of Commerce & Community Development to be used for brownfield clean-up projects around the state.
Revolving Loan FundProgram for State of Vermont
ENVIRONMENTAL SERVICES, NEW HAMPSHIRE DEPARTMENT OF
Supplemental funding for New Hampshire Department of Environmental Services' Brownfields Cleanup Revolving Loan Fund
Stimulus - NHDES Brownfields Cleanup Revolving Loan Fund
City of Newark 2009 U.S. EPA Brownfields Cleanup Grant: International Metallurgical Services Site
Conducting a hazardous substances cleanup at the International Metallurgical Services site.
Jersey City Redevelopment Agency U.S. EPA Brownfields Cleanup Grant: 75 Woodward Site
Conducting a hazardous substances cleanup at the 75 Woodward site.
Tasers, Computer Voice Stress Analyzer II
The Rutherford County Sheriff's Office will use the award to enhance the department with upgrades and integrate several divisions with the purchase of much needed law enforcement equipment.  These purchases include a tactical response vehicle f
Rutherford Coun ty Sheriff's Office Enhancement Project and Upgrade Implementation
The city of Fife will use its Fiscal Year 2009 Recovery Act JAG award to support technological upgrades for the Fife Police Department.  Funds will be used to purchase a multiband radio that will allow first responders to communicate in the fie
BJA Fy 09 Recovery Act Edward Byrne Memorial Justice Assistance Grant Program Local Solicitation
Purchase of new police vehicles and equipment for vehicles.
Purchase of New Police Vehicles/Equipment
Enhance Officers safety, encourage positive police and citizen interaction and be a valuable deterrent against law suits that can hinder or cause an economic disaster a department or city.
Edward Byren Memorial Justice Assistance Grant (JAG) Formula Program:  Local Solicitation
Prison boughtprotective vests, guns and ammo
The Honolulu Police Department and the Department of the Prosecuting Attorney will use Recovery Act JAG funding to support projects aimed at improving the efficiency and effectiveness of law enforcement operations and prosecution.  Through the
FY2009 Recovery Act Justice Assistance Program
Purchased Six WatchGuard Digital in Car Video Systems for six of our patrol vehicles
BJA FY09 recovery Act Edward Byrne Memorial Justice Assistance Grant Program Local Solicitation. Goals: 1.Provide more efficient law enforcement and public safety services 2.Expand capabilities 3.Employee education and development	  Strategies:
Kissimmee Police Department Training and Equipment / To the Kissimmee Police Department to provide training, to purchase equipment, and to lease vehicles and motorcycles in order to improve and enhance our law enforcement programs and services.
FY2009 Recovery Act JAG -- Public Safety Equipment to enhance the effectiveness of public safety services provided to the citizens of Campbell County, Wyoming  through deploymnet of additioanl specialized equipment.
The City of Ardmore and Carter County Sherriff's Departments goals are to provide equipment to our personnel needed to prevent crime and provide the level of response capability to officers when dealing with heavily armed, barricaded or otherwi
Scott County will utilize funds to purchase police cruisers and equipment.  These cruisers will replace ones that have over 250,000 miles and pose a severe safety problem and a high maintenance cost.  Purchasing of these cruisers will allow Sco
The City of Webster will use the Recovery Act jag funds (29446)to enhance their our law enforcement efforts by purchasing a k-9 unit, vehicle container, radar trailer, surveillance system, ballistic shield, reciever and a laptop computer.  The
The funding has been made available to the County of Wayne, Michigan and 27 municipalities within the County. The primary  utilization of this fuding will be for technology enhancement, equipment purchases, retention of employees that would hav
Purchase of 15 Mobile Data Terminals and 4 mini computers for law enforcement.
Law Enforcement Initiatives for the City of Abilene, Texas and Taylor County.  The Abilene Police Department will utilize grant funds to purchase law enforcement equipment to enhance communication capabilities.  These funds will be used to repl
The City of Stamford, through the Stamford Police Department (SPD), will use the Recovery Act JAG funds to enhance several law enforcement and crime prevention programs. The first project will be to implement a Law Enforcement Career (Police Ca
The Enhancement  of Law Enforcement and Crime Prevention Programs
The City of West Point ? West Point Police Department and Clay County are applying for the Edward Byrne Memorial Justice Assistance Grant JAG Formula Program money in the amount of $38,800.  It will be used to purchase an AFIS Fingerprint Machi
Public Safety, Disaster Preparedness & Relief N.E.C.
The purpose of this project is to enhance technical surveillance equipment and to purchase interoperable mobile radios to allow law enforcement officers to communicate with multi-discipline emergency responders.  The new technical surveillance
BJA FY09 Recovery Act Edward Bryne Memorial Justice Assistance Grant Program Local Solicitation
FY 2009 Recovery Act JAG Program  The title of this program is Reduce Crime and Violence with Improved Communications and Accessibility to Police Data by Officers in the Field
Purchase two mobile crime scene vehicles, general equipment, and NCIC software.
Award Description NO FEDERAL FUNDS HAVE BEEN REQUESTED/RECEIVED AS OF THIS DATE Purpose  The purpose of this project is ?to improve the functioning of the criminal justice system and to assist local . . . efforts to prevent or reduce crime and
Fund a Communications Officer position that was deleated in FY 2009 due to budget shortages and to purchase ANSI compliant raincoats for Officers
Purchase Items to fully equip four (4) additional Officer positions
The City of Ennis Police Department will use these funds the enhance the capabilities of it's Police Department by increasing prosecutorial success by purchasing a Multi Channel Digital Voice Recorder and increase officer safety by purchasing p
The grant funds were used to start two K9 Units and purchase one AFIS unit.
ST TAMMANY PARISH SHERIFF'S OFFICE (INC)
St Tammany Parish Recovery Act JAG Project
This project is in line with ARRA of 2009 goals to preserve and create jobs, promote economic recovery, to assist those most impacted by the recession, to provide investments needed to increase economic efficiency by spurring technological adva
The Morristown (TN) Police Department and the Hamblen County Sheriff's Department sought to fund a Technological Enhancement of Evidence Collection and Investigation Capability program through disparate allocation award to increase the departme
Technological Enhancement of Evidence Collection and Investigation Capability program
The Edward Byrne Memorial JAG Program is the primary provider of federal criminal justice funding to state and local jurisdictions.  JAG funds support all components of the criminal justice system, from multijurisdictional drug and gang task fo
Southeast Area Drug Enforcement Task Force
Keeping Officers on the Street Retention/Hiring program
Prince William County (PWC) expanded and enhanced its community corrections program by creating new positions equivalent to two full time employees (2 FTEs).  The new positions include 3 part-time program officers (1 FTE) and one full-time ment
Expansion and Enhancement of the Prince William County Community Corrections Program
The Johnson County Sheriff's Off. plans to utilize their share of the Jag funds to implement ,equip, and train a jail extraction unt. Will also purcahse items to assist with locating cell phnoe users involved in criminal activity. Numerous piec
Oakland County, serving as the fiscal agent for this award, will share the Fiscal Year 2009 Recovery Act JAG award with 20 disparate jurisdictions within the county. In a disparate situation, the units of local government must apply for an awar
BJA FY09 Recovery Act Edward Byrne Memorial Justice Assistance Grant Program Local Solicitation
The City of Richmond will use Recovery Act JAG funds to support continued law enforcement and crime prevention initiatives. Through the grant, the Richmond Police Department will support salaries of police officers within the Richmond Police Pa
City of Richmond Public Safety, Intervention and Enforcement Project
In collaboration with the Norfolk Police Department (NPD), the Office of Community Empowerment, the Department of Human Services, the Sherriff's Office, the Commonwealth Attorney's Office, the Community Services Board (CSB), the School System,
City of Norfolk Byrne-JAG Stimulus Grant
Technology-Based update for the Fremont Police Department.  Purchase of four laptop computers for use in cruisers, airtime using Verison and access to the state computer system, LEADS/NORIS.
FY09 Recovery Act Edward Byrne Memorial Justice Assistance Grant Program Local Solicitations
CSB/ADS Agency 757656 Index/Grant 779025 75092G 10001 Job 75STIM
Fairfax County created 4.0 FTE positions and hired 4.0 FTE Substance Abuse Counselors (SAC) for the Diversion to Detox Program.  The staff work with law enforcement providing on-site assessment of individuals that are Drunk in Public.  If appro
The grant award of $48,264.00 is being used by two agencies in Steuben County in the State of New York. The agencies agencies using the award are the Hornell Police Department and the Corning Police Department. The Hornell Police Department was
Cibola County will use the Recovery Act JAG funds to procure a patrol vehicle and associated equipment.  The equipment package includes a light bar, push-bumper, emergency lights, weapons mounting system, and wiring.  The patrol vehicle is to b
Mobile Data Computer Project. Computers i9n law enforcement vehicles
To purchase police cruisers, radar units, mobile command post equipment, and tasers.
The $66,089 in JAG funding will allow the Village to retain a Code Compliance Officer position as part of the Rental Property Licensing Program. The program supports the Village of Wellington?s objective to maintain a high quality safe rental h
Village of Wellington Rental Property Licensing Program
The Edward Byrne Memorial Justice Assistance Grant (JAG) Formula Program:  Local Solicitation, allows local governments to support a range of activities to prevent and control crime based on their own local needs and conditions.
Department of Public Safety Information Technology Project
Intelligence Analyst - part time position without benefits.  The mission of the Intel Analyst is to support the intelligence function through the analysis of data gathered and completion of assessments on crime groups which are prioritized as t
Law enforcement equipment(2 motorcycles, special ops vehicle, HQ armory equip, high-powered binoculars,batteries for bike patrol), scheduling software, crisis communication system,training on system, internal affairs records management system,
The county of York, boroughs of Hanover and Red Lion Borough, city of York, and the townships of Fairview, Hellam, Newberry, North Cororus, Penn, Springettsburg, Spring Garden, West Manchester Township, and York have been identified as disparat
The City of Bozeman Police Department requested $65,741 to purchase electronic ticketing system equipment. The electronic ticketing system will: 1) allow officers to electronically process traffic citations safely and efficiently, 2) provide im
FY09 Recovery Act Edward Byrne Memorial Justice Assistance Grant Program Local Solicitation
TO UPGRADE THE DATABASE FOR PROPER AND PRECISE REPORTING AND FOR OFFICER SAFETY.
Update technology between local law enforcement agencies.
Program will seek to enhance the county victim services program, enhance officer safety in patrol vehicles and allow for expansion of the victim services volunteer program.
Victim Witness Specialized Direct Services Project
The Edward J. Byrne Memorial Justice Assistance Grant Funds distributed through the American Recovery and Reinvestment Act of 2009 allowing the Rankin County Sheriff?s Department and the City of Pearl Police Department to purchase computers and
PRESTON COUNTY ECONOMIC DEVELOPMENT AUTHORITY
This award provides stimulus funding to the Preston County Economic Development Authority (PCEDA) to be used to conduct commmunity-wide assessments at potential brownfields site contaminated with hazardous substances.  The PCEDA will conduct si
This award provides stimulus funding to the Town of Pulaski to be used to conduct community-wide assessments at potential brownfields sites contaminated with hazardous substances. This grant recipient will conduct site priorization and Phase I
ARRA - BROWNFIELD CLEANUP - FORMER SAYRE RAILYARDS (HAZARDOUS SUBSTANCES) This award provides stimulus funding to the Central Bradford Progress Authority for clean up of hazardous substance contaminants at the Former Sayre Railyards site. Durin
MONTGOMERY COUNTY COMMUNITY COLLEGE FOUNDATION
This award supports the clean-up of hazardous substance contaminants at the old PECO building parking lot site located at 140 College Drive, Pottstown, PA. The objective is to remove human exposure to arsenic and lead in the soil and reducing t
Supplemental Revolving Loan Fund for hazardous substances
Supplemental Revolving Loan Fund for Hazardous Substances
The Clean Water State Revolving Fund (CWSRF) finances high priority infrastructure projects needed to clean and restore the District's streams and rivers.
CWSRF -Green projects such as green roofs, porous pavements, rain gardens, and tree planting.
The Arizona Department of Environmental Quality was awarded a State Clean Diesel Program Grant to fund a Truck Stop Electrification project targeting heavy duty diesel trucks in southern Arizona. The general purpose of the grant is to reduce di
ENVIRONMENTAL PROTECTION, FLORIDA DEPARTMENT OF
The Florida Department of Environmental Protection was awarded a State Clean Diesel Program Grant to fund retrofit projects  for a School Bus Retrofit and Truck Stop Electrification (TSE) program targeting school buses and trucks in Florida. Th
ENVIRONMENTAL QUALITY, TEXAS COMMISSION ON
The Texas Commission on Environmental Quality was awarded a State Clean Diesel Program Grant to fund a retrofit project or program targeting school buses in Texas.  The general purpose of the grant is to reduce diesel emissions and improve air
State Clean Diesel - Texas Clean School Bus Program
ENVIRONMENTAL PROTECTION, WEST VIRGINIA DEPT OF
Hybrid Diesel Electric Transit Buses and On-Road Heavy-Duty Replacement Vehicles
American Recovery and Reinvestment Funding for the Iowa State Clean Diesel Grant Program  Iowa Department of Natural Resources was awarded a State Clean Diesel Program Grant to fund retrofit/idle reduction/replacement/repower and upgrades/emerg
ENVIRONMENTAL QUALITY, NEBRASKA DEPARTMENT OF
The Nebraska Department of Environmental Quality was awarded a State Clean Diesel Program Grant to fund retrofit/replacement/repower projects targeting diesel powered fleets (private and public trucks and buses, school buses, agriculture, and i
ENVIRONMENTAL QUALITY, MONTANA DEPARTMENT OF
Montana Department of Environmental Quality (DEQ) was awarded a State Clean Diesel Program Grant to fund school bus replacement program targeting school bus fleets in poor air quality areas in the state. The general purpose of the grant is to r
The ARRA funding assists the State of Ohio with the financing and construction of drinking water facilities, green infrastructure, and drinking water related activities.
HEALTH AND ENVIRONMENTAL CONTROL, SOUTH CAROLINA DEPARTMENT OF
This agreement provides funding under the ARRA of 2009 to the State of South Carolina to capitalize its revolving loan fund for financing the construction of drinking watr facilities, green infrastructure, program administration, and drinking w
Safe Drinking Water State Revolving Fund
PUBLIC HEALTH, CONNECTICUT DEPARTMENT OF
ARRA Drinking Water State Revolving Fund - the Connecticut Department of Public Health is committed to using the ARRA capitalization grant to provide assistance to public water systems for capital improvement projects which will proceed quickly
THIS AWARD PROVIDES $14,950,000 IN FUNDING UNDER THE AMERICAN RECOVERY AND REINVESTMENT ACT OF 2009 TO THE STATE OF NEW MEXICO TO CAPITALIZE ITS DRINKING WATER REVOLVING LOAN FUND, WHICH FUNDS PROVIDE FOR (1) AFFORDABLE FINANCING TO DRINKING WA
Administration of Air and Water Resource and Solid Waste Management Programs
This agreement provides funding under the ARRA 2009 to the Commonwealth of Puerto Rico to Capitalize its Revolving Fund for the Financing for the construction of drinking water facilities, green infrastructure, program administration and drinki
The National School Lunch Equipment project of the Child Nutrition and Recovery Act utilizes great funds to improve the quality and caliber of food service, the overall safety of food service areas and to improve the healthiness of the meals th
ARRA Brownfields Job Training Cooperative Agreement.  This award provides stimulus funding to the grantee for training of residents for the skills necessary to gain employment with companies that assess and remediate brownfield properties in th
This award provides American Recovery & Reinvestment Act funding to St Louis Coummunity to train residents for the skills necessary to gain employment with companies that assess and remediate brownfields properties in the St Louis Metro communi
American Recovery and Reinvestment Act - St Louis Community College - Brownfields Job Training Cooperative Agreement
The agreement provides American Recovery and Reinvestment Act funds as an additional financial assistance source for the recipient's efforts to assess and cleanup petroleum releases from Leaking Underground Storage Tanks (LUST) sites in the Sta
ARRA - LEAKING UNDERGROUND STORAGE TANK PROGRAM - Illinois Environmental Protection Agency
ENVIRONMENTAL MANAGEMENT, ALABAMA DEPT OF
Leaking Underground Storage Tank (LUST) investigations and cleanups in Alabama
ENVIRONMENT AND NATURAL RESOURCES, NORTH CAROLINA DEPARTMENT OF
Funds provided through this grant will be used to address assessment and cleanup at approximately 172 leaking petroleum underground storage tank sites in North Carolina.  Four environmental service providers and two analytical laboratories will
Leaking Underground Storage Tank Trust Fund Program
This agreement provides American Recovery and Reinvestment Act funds as additional financial assistance source for the recipient's efforts to assess and cleanup petroleum releases from the Leaking Underground Storage Tanks (LUST) sites in Puert
Puerto Rico LUST Fund ARRA of 2009 Project
The assistance agreement provides funding under ARRA to develop 3 water quality management plans, conduct monitoring for a list of impaired streams and lakes to complete the Total Maximum Daily Loads (TMDL) studies, and to develop green infrast
ARRA - Water Quality Management Planning - Section 604 (b)
The potential for widespread dissemination of lethal poxviruses such as smallpox during bioterrorism has led to renewed scientific efforts to understand the pathogenesis of this virus and related orthopoxviruses.  Poxviruses have evolved many s
This ARRA grant supports water quality management planning activities in Florida. The specific activities being funded are 1) under contract with SAIC (private contractor), development of basin management plans--specific plans for watershed res
This ARRA grant supports water quality management planning activities in North Carolina.  Specific activities are:  o Continuation of water quality monitoring for planning, assessment, and reporting supporting 10 FTEs,  o Special watershed samp
To support water quality mgmt planning activities by: 1. Creating nutrient criteria development framework for wadeable streams; 2. Performing water quality assessment near active surface coal mining facilities; and 3. Develop procedures for con
OREGON DEPARTMENT OF ENVIRONMENTAL QUALITY
(to be implemented by the Rogue Valley Council of Governments (RVCOG)) - $89,440 For the Bear Creek Watershed TMDL and the Rogue River Basin TMDL, provide:  professional planning assistance to the 26 Designated Management Agencies (DMAs) to pr
ARRA of 2009 Oregon Water Quality Management Planning Grant
ENVIRONMENTAL MANAGEMENT, RHODE ISLAND DEPT OF
The award supported water quality management planning activities authorized under the Clean Water Act and ARRA.  The Rhode Island Department of Environmental Management (RIDEM) used the funds for three purposes: (1) nutrient criteria developmen
STIMULUS- RI Water Quality Management Planning
VIRGINIA DEPARTMENT OF ENVIRONMENTAL QUALITY
will address 12 impaired urban segments and has CSP issues. (5) The DEQ internal task is to develop a Water Quality Planning Interface Module for TMDLs and Water Permits: spatial GIS data layers and tracking and analysis of significant sources
FY2009 VA Department of Environmental Quality ARRA Water Quality Management Program Grant
The Award supports water quality management planning activities authorized by the Clean Water Act and the American Recovery and Reinvestment Act of 2009.  The funds will be used on the following projects:  604(b) Stormwater – Component One: W
FY 2009 West Virginia DEP ARRA WQMP Grant
This grant funds 3 important water quality management planning projects.
Nebraska American Recovery and Reinvestment Funding for Water Quality Management Planning.  This project supports water quality management planning activities that are authorized under the Clean Water Act and the ARRA.  This project will provid
Nebraska American Recovery and Reinvestment Funding for Water Quality Management Planning
ENVIRONMENTAL QUALITY, UTAH DEPARTMENT OF
This award was used to complete four separate activities. 1. Creation of a Statewide Water Quality Monitoring Council, $75,000: All water quality management activities throughout Utah are informed by monitoring data, yet the Division of Water Q
NATIONAL ASIAN PACIFIC CENTER ON AGING INC
Senior Environmental Employment Program for the Region V Operations Stimulus Activities.  This Cooperative Agreement will provide support for Senior Environmental Employment(SEE) Program enrollees to work in Region V offices and to support EPA
Senior Environmental Employment Program for the Region V Operations Stimulus Activities
Alcoholism (alcohol abuse and dependence) is a common disorder with a peak age of onset in early adulthood and a complex etiology. Twin studies comprised predominantly of participants of European Caucasian ancestry have shown genetic factors co
Alcohol Involvement in Asian American Men and Women
The goal of this project is to develop software that simplifies the analysis of brain-image  data. We will make all of these software components available from a web-accessible  image database. We expect that, as we implement more components of
SPATIALLY ORIENTED DATABASE FOR DIGITAL BRAIN IMAGES
Alzheimer's disease (AD) is the most common neurodegenerative disease in the US, affecting over 4 million people over the age of 65 years.  As the population of the world ages the number of people suffering from AD will increase rapidly during
GENOMIC SEARCH FOR SUSCEPTIBILITY TO ALZHEIMER DISEASE
Pertussis toxin (PTX) is a complex AB5 toxin, comprised of the enzymatically active, 'A' subunit (S1), and the binding, 'B' oligomer (PTX-B), composed of five subunits S2, S3, S4, and S5, found in a 1:1:2:1 ratio. The B portions of AB toxins tr
Biologic Activities of the Pertusis Toxin B-Pentamer
Asthma is the most common disease of childhood in the United States. The role of microbial flora and allergens in asthma development is poorly understood. We found reduced pro-inflammatory Th2 cytokine production at age 2, reduced risk of eczem
The Epidemiology of Home Allergens and Asthma
Influenza virus causes a respiratory infection that leads to morbidity and mortality worldwide. The virus infects the respiratory epithelium and replicates rapidly to peak levels in two days. It is eventually cleared from the lungs by a strong
Cholera is a severe epidemic diarrheal disease caused by the gram-negative aquatic bacterium Vibrio cholerae. As is true for most bacterial pathogens, attachment to biotic surfaces such as the exoskeletae of copepods and the intestinal epitheli
inhibitory receptor- negative NK cells. This will provide the basic information needed for future studies on control of NK developmental decisions in health and disease. This study will 1) develop a clear understanding of the multiple layers o
Molecular Mechanisms Controlling NK Receptors
TORREY PINES INSTITUTE FOR MOLECULAR STUDIES, INC.
Some viruses are able to persist in a latent or inactive form in normal healthy individuals, but can reactivate causing a range of diseases, including cancer, in immunocompromised individuals such as AIDS patients or transplant recipients, who
Immunological control of a persistent viral infection
The Role of Oderant Binding Proteins in Anopheline Mosquito Odor Perception The work proposed here will investigate the specificity of odorant recognition in the malaria mosquito, Anopheles gambiae, and correlate specific odor stimuli with quan
The Role of Odorant Binding Proteins in Anopheline Mosquito Odor Perception
The use of pigs as organ donors for human transplantation represents a solution to the escalating shortage of organs that are available for patients with end-stage diseases. Wild type pig organs are hyperacutely rejected, however, by pre-existi
Non-Human Primate Models for Human Xenotransplantation
The purpose of this proposal is to delineate the role of NF-(B subunits in the development of inflammatory bowel disease. NF-(B is a transcription factor family consisting of 5 subunits. Activation of NF-(B in response to Toll-like receptor (TL
Inhibition of Microflora-Induced Colitis by NF-kB
Schistosome parasites cause infectious disease in over 200 million humans globally; some 600 million more are at risk of infection. This disease affects development in children, reduces general health and may ultimately lead to death. The paras
Despite more than 20 years of molecular investigation, little is currently known about the essential process of the transcription of protein-coding genes in Leishmania and other trypanosomatids, other than that it differs from that in other euk
TRANSCRIPTION OF PROTEIN-CODING GENES IN LEISHMANIA
DESCRIPTION (provided by applicant): Varicella zoster virus (VZV) causes varicella during primary infection, persists in sensory ganglia and may reactivate from latency to cause zoster. VZV pathogenesis depends upon its tropisms for T cells, sk
Varicella-zoster Virus: Tegument Proteins in Pathogenesis
The arenaviruses cause devastating viral hemorrhagic fever (VHF) diseases of humans with high fatality rates. Because there is negligible or at best limited antiviral treatment available for these diseases, especially the Old World Lassa fever
Therapeutics to Prevent/Treat Lassa Fever Virus
Our studies are directed at understanding how the immune system distinguishes between the antigens present in our own bodies and those of disease producing organisms such as viruses and bacteria.  Studies from other laboratories have shown that
Congenital Myotonic Dystrophy 1 (DM1) causes a delay of development in newborn children. There is no cure for this devastating multisystemic, neuro-muscular disease. This project will address the molecular mechanisms delaying development of mus
Molecular Mechanisms of Myotonic Dystrophy
Toward Tissue Engineering of the Knee Meniscus. This proposal seeks to tissue engineer allogeneic and xenogeneic anisotropic meniscus constructs that also capture the regional variations present in the native tissue. The aims of the proposal ar
Toward tissue engineering of the knee meniscus
The overall goal of this project is to characterize antigen loading and presentation by MHC and MHC-lik.e molecules primarily through three-dimensional structure determination using x-ray crystallography. The innate and adaptive immune systems
Structural Immunology of Classical and Non-Classical MHC
The p73 gene, a member of the p53 family, is controlled by two alternate promoters.  When the upstream P1 promoter is used for p73 expression, several TAp73 isoforms are produced.  When the P2 promoter in intron 3 is used for p73 expression, se
Mechanism of P73-Dependent Tumor Supression
DESCRIPTION (provided by applicant): The long-term objective is to determine the role of respiratory tract cytochrome P450 (P450 or CYP) enzymes in target tissue metabolic activation and toxicity of environmental chemicals. Our focus continues
HUMAN CYP2A AND RESPIRATORY TRACT XENOBIOTIC TOXICITY
The broad long term objective of this proposal is to understand the pathogenesis of natural killer (NK) LGL leukemia. The mechanisms responsible for expansion of leukemic NK cells are not completely known. Leukemic NK cells are characterized by
Radiation Biology of EPR Oxygen Images Abstract: Electron Paramagnetic Resonance (EPR) Oxygen Images (EPROI) have been shown to provide quantitative localized pO2 images in FSa fibro sarcomas grown in the legs of C3H mice. The widths of narrow
Cocaine abuse continues to be an important public-health concem. Because cocaine abuse is not an automatic consequence of cocaine use, it is important to study factors that may lead from the latter to the former. Two such factors that have been
Behavioral Determinants of Cocaine Tolerance
The use of nicotine via cigarette smoking forms lifelong memories that are recalled in response to environmental cues associated with previous nicotine use. This recall increases nicotine craving and is a factor for the continued use of nicotin
of the system when it responds to phasic events.  Our preliminary data suggest that vSub-induced activation of DA neuron population activity may underlie behavioral sensitization to amphetamine.  Thus, sensitization to amphetamine by stress or
Stress-Induced Alterations in Amygdala-LC Interactions
Our long-term goal is to understand the organization of the brainstem auditory pathways in terms of connections among the multiple neuronal types that form them. The objective of the proposed studies is an analysis of the origins and terminatio
Neuron loss, either dependent or independent of sensory hair cell loss, contributes significantly to hearing loss, particularly in the aging population. Future treatments, particularly stem cell therapies, will require detailed understanding of
Incomplete healing of bone defects in the craniofacial skeleton is common. Osteogenic proteins, including bone morphogenetic protein 2 and 4 (BMP2, BMP4), promote healing in bone defects, but the proteins' short half-lives and rapid clearance b
Muscle-Based Tissue Engineering to Improve Bone Healing
Musculoskeletal & Connective Tissue Diseases
Vitamin D receptor coactivators in bone.  1,25-dihydroxyvitamin D3 (1,25(OH)2D3) is the bioactive hormone of the vitamin D endocrine system. It functions via the vitamin D receptor (VDR) to impact bone by increasing intestinal calcium absorptio
Hepatitis C virus (HCV) is a major health problem affecting approximately 200 million throughout the world. Although new therapies have improved the rates of sustained response, a large proportion of patients (~50%) fail to respond to antiviral
Immune Responses in Acute Hepatitis C Infection
The goal of this research proposal is to understand the role of primate primary visual cortex (V1) and second visual cortical area (V2) in the processing of visual depth information. In the previous funding cycles, we investigated the organizat
Sub-Voxel Tissue Characterization with In-Vivo MRI
Development and function of the ocular lens depends on controlled proliferation of epithelial cells, and on migration, elongation, adhesion, and cytoarchitecture of the resulting fiber cells. Neither the identity of the molecular mechanisms tha
.Rho GTPases IN THE LENS-ROLE IN GROWTH & DEVELOPMENT
TEXAS TECH UNIVERSITY HEALTH SCIENCES CENTER
Nanophthalmos is a rare genetic disorder in which both eyes are well formed, but have unusually short axial lengths. Extreme hyperopia, from +8 to +25 diopters, occurs because the image-forming cornea and lens are too close to the retina. As ad
Genetic Basis of Nanophthalmos and Human Ocular Biometry
This proposal is aimed at understanding the putative regulatory role(s) of matrix metalloproteinases in glucose-induced alterations in metabolic functions of retinal capillary cells leading to their demise, and the development of diabetic retin
ROLE OF RAS IN RETINAL CELL DEATH IN DIABETES
Cataracts affect an estimated 20.5 million Americans, expected to rise to 30.1 million by 2020. Removal of cataracts and treatment for the most common complication of this procedure, posterior capsule opacification (PCO), are major Medicare exp
Regulation of Lens Cell Coupling and Differentiation
The long range goals of our research program are to develop and apply new techniques to study biological electron transfer reactions. These reactions play essential roles in numerous biological processes important to human health, including ox
This project will study fundamental properties of hemes derivatives, especially those with the gaseous ligands NO, O2, CO, and H2S. We are studying the dynamics of iron in these derivatives that will provide essential information on how the com
X-Ray and Chemical Studies of Metalloporphyrins
Ready access to seven-membered rings systems will facilitate the synthesis of  biologically important compounds possessing this ring system. Three carbocyclic cores  of three targets, thapsigargin, grayanotoxin III and guanacastepene J, will be
Allenic [2 + 2 + 1] Reactions Enabling Syntheses of Natural Products with 7-Membe
The degradation of proteins within cells controls multiple cellular processes.  Protein degradation is used to control the division of cells, and defects in degrading cell cycle regulatory proteins can lead to cancer.  Many cellular proteins ar
Genetics of Cell Cycle Regulators in C. elegans
Linear chromosomes terminate in specialized nucleoprotein structures called telomeres, which are required for genomic stability and cellular proliferation. Telomeres end in an unusual GT-rich 32 single-strand overhang that requires a special ca
Single Stranded DNA Recognition in Telomeres
One of the most challenging problems in molecular design is developing molecules that can bind protein surfaces and block protein-protein interactions. The ability to modulate protein-protein interactions in a directed fashion opens the possibi
In Vitro Selection of Proteins via mRNA-Protein Fusions
DESCRIPTION (provided by applicant): This proposal builds on previous research that developed the dog as a model for the genetic analysis of complex traits. A working relationship with owners and breeders of Portuguese Water dogs (PW dogs) has
GENETIC ARCHITECTURE OF THE MAMMALIAN (CANID) SKELETON
The long-term objective of this application is to elucidate the molecular mechanisms underlying TGFß regulation and functions, and understand the molecular basis of how alterations in TGFß responses lead to deregulation of growth control in h
REGULATION OF TGF-BETA RECEPTOR SIGNALING BY HSP90
The long-term project goal is to create small, highly fluorescent, and optically modulatable nanomaterials to enable a whole new array of high sensitivity imaging and detection capabilities in extremely high background biological environments.
ARRA: OPTICALLY MODULATED, SEQUENCE-AND COLOR-TUNABLE SINGLE AG NANODOT BIOLABELS
Warfarin is the most widely-used oral anticoagulant in the world, but therapy is difficult to manage because of wide inter-individual variability in response to the drug, a low therapeutic index, and the resulting serious (sometimes fatal) cons
Pharmacogenetics of ADRs: Warfarin Toxicity
Androgen receptor regulation of reproductive function -- ARRA  MAGE-11 (melanoma antigen-A11) was identified as a novel androgen receptor (AR) coregulator that increases AR transcriptional activity. MAGE-11 is a member of the MAGE gene family t
Androgen receptor regulation of reproductive function -- ARRA
The molecular mechanisms underlying uterine smooth muscle excitation during pregnancy are unknown, and this deficit has hampered the development of effective therapies for uterine dysfunction. The maintenance of uterine quiescence during pregna
Regulation of Uterine Smooth Muscle Excitability
The long-term objective of this application is to better understand the phenomenon of progesterone resistance in endometriosis in order to develop alternate therapies for this disease. The action of progesterone receptor (PR) in the physiologic
Mechanisms of Progesterone Receptor Action in Endometriosis
Medical Disciplines & Occupations Research
Recovery Act funds have been awarded for the study of 'Effects of sex and fat distribution on sleep disordered breathing'. This award will support two additional senior faculty members (total of 25% effort ), two new junior faculty (30% effort)
EFFECTS OF SEX AND FAT DISTRIBUTION ON SLEEP DISORDERED BREATHING
DESCRIPTION (provided by applicant): We hypothesize that small fractions (1-5 wt%) of cholesterol reduce the crystalline ordering of saturated lipids in lung surfactant monolayers, leading to a reduction in the shear viscosity, which enhances t
Lipid and Protein Effects on Mono-Layer Stability
Natural killer (NK) cells develop from primitive hematopoetic stem cells into functional anti-tumor effector cells that express receptors recognizing MHC class I ligands. In addition to the killer immunoglobulin-like receptor (KIR) family, NKG2
Our plan is to develop a new therapy for heart disease.   Abstract:  Cardiovascular disease is a major cause of mortality and morbidity and development of therapies that address its underlying causes is an important public health priority.  Wit
Therapeutic Approaches to Dysregulated HDL Metabolism
We have shown in the fetus and newborn, that in pulmonary vascular relaxation induced by cGMP-elevating agents, cGMP-dependent Protein Kinase (PKG) plays a primary role. We have also reported that hypoxia attenuates nitric oxide-cGMP-mediated r
Mechanisms of cGMPMediated Vasodilation in Perinatal Lung
The long-term goal of this proposal is to identify functions and determine mechanisms of the fibrinolytic system, and its inhibitors, in physiological and pathological processes utilizing cell based and in vivo models. The availability of mice
Pathological Consequences of the Plasminogen System
Inhibitory antibodies to factor VIII develop in approximately 30% of patients with severe and moderately severe hemophilia A in response to infusions of factor VIII. Inhibitor development is associated with a lower quality of life and an increa
The long-term goal of this project is to elucidate the functional roles of glycosphingolipids (GSLs), particularly gangliosides, during normal nervous system development and under pathological conditions. These molecules are abundant in the ner
SPHINGOGLYCOLIPIDS OF NORMAL AND PATHOLOGICAL BRAINS
The long term goals of this research are (1) to understand how cortical networks represent and transform plans into voluntary movement and (2) to use knowledge of cortical representation and processing for movement to develop neural prosthesis
STATIC AND DYNAMIC ORGANIZATION OF PRIMATE MOTOR CORTEX
Multiple sclerosis (MS) is a debilitating neuroimmunological and neurodegenerative disorder affecting more than 400,000 individuals in the United States. Epidemiological and genetic studies have produced overwhelming evidence for a genetic infl
Genetic Epidemicology of Multiple Sclerosis
Abnormal accumulation and deposition of the amyloid ss-protein (Ass), a prominent pathological feature of patients with Alzheimer's disease (AD) and related disorders, can occur from increased production but in most cases is likely due to decre
ARRA: Pathologic Interactions of Amyloid Beta-Protein
The suprachiasmatic nucleus (SCN) is the master circadian clock in mammals. Individual SCN neurons are cell-autonomous oscillators with diverse free-running periods of activity (19 to 28 hours). Intracellular communication is required to synchr
Cellular Electrophysiology of the Suprachiasmatic Nuclei
This project involves the identification of genes in mice that determine their susceptibility to experimentally induced seizures. Whereas the short term goal of the project involves the identification of seizure susceptibility genes, the longer
Secretion is one of the most ubiquitous of cellular processes. Indeed, it is central to such diverse biological functions as information processing, reproduction, motility, temperature regulation, metabolism, the immune response, and signal tra
OPTICAL STUDY OF SECRETION IN MAMMALIAN NERVE TERMINALS
Aim 1:   To test the hypothesis that a-Syn inhibits TH in vivo by effects on PP2A.  Our in vitro data suggest that a-Syn inhibits TH and reduces DA synthesis, by increasing PP2A activity. To assess this in vivo, we will use nigral and striatal
a-Synuclein and Dopamine: Implications of Parkinsonism
Notch signaling in mammalian neural progenitors, this work will contribute to the treatment of nervous system disorders, including brain cancer and neurodegenerative diseases, and to the treatment of traumatic brain injury.
NOTCH SIGNALING IN MAMMALIAN NEURAL PROGENITORS
The overall goal of the proposed work in this application is to identify the biochemical mechanisms responsible for initiating protein synthesis during synaptic plasticity and memory, and whether these mechanisms are altered and can be reversed
Translation Regulation in Hippocampal LTP and LTD
Since its introduction over a decade ago, functional magnetic resonance imaging (fMRI) has revolutionized studies of the working human brain. While most fMRI studies measure the blood oxygenation level dependent (BOLD) response to a functional
that optimally precedes successful manipulation and which is derived from the availability of an integrative and predictive analytical tool. PUBLIC HEALTH RELEVANCE: The complexity of scientific information is making it unavoidable that comput
Evolutionary Models of the Immune System
The importance and need for continuous metabolites monitoring cannot be overemphasized. Most recent developments for in vivo monitoring devices have focused on miniaturization and the exploratory use of new functional materials. As most biosens
Intelligent Optofluidic Device for Continuous Metabolite Monitoring
The Specific Aims of the proposal is modified to reflect a change in scope, according to recommendations   from the review panel. The aims of this Phase II continuation proposal are to utilize fully humanized recombinant lactoferrin (rhLF) as a
Lactoferrin as an Adjuvant for Cellular Immunity
DESCRIPTION (provided by applicant): Interthyr Corporation (IC) is requesting an Advanced Technology Phase II STTR award to develop a novel agent with a new therapeutic paradigm: Inhibition of Toll-like receptor (TLR) expression and signaling i
TLR Signal Inhibition:  A Novel Therapeutic Paradigm
The overarching aim of this innovative proposal is to develop and then commercialize a non-invasive topical product which is safe and easy to administer that treats severe uveitis, including intermediate and posterior uveitis. Uveitis is the th
Non-Invasive Drug Delivery To Treat Severe Uveitis
This project is about regulatory T cells, which are essential components of the immune system. Through experiments conducted during the previous funding cycle we observed that in the presence of Tregs, antigen-presenting dendritic cells (DCs) a
CharacterIzation of Lymphocytes that suppress EAE
This award is a bridge grant that has allowed us to continue experiments that support an RO1 application. The RO1’s overall purpose is to study how Mycobacterium tuberculosis (Mtb), the causative agent of human tuberculosis, acquires iron, an
Mechanisms and regulation of Mycobacterium tuberculosis iron acquisition
in our subjects).  We have not detected binding to donor MHC but have found binding to host MHC in our preliminary Class I tetramer experiments.  The binding of T cells to class I and class II tetramers will be compared between subjects with a
Thymic Transplantation in Complete DiGeorge Syndrome
It is generally accepted that for an individual species to co-exist indefinitely with the thousands of species that make up the intestinal microbiota it must use one or a few limiting carbon sources better than all other species (nutrient-niche
GROWTH AND COLONIZATION OF THE INTESTINE BY E. COLI
The rapid rise in antibiotic resistance in the past two decades increases the need for alternative therapeutic strategies. A current approach to developing new antibiotics is to target non-essential functions that reduce virulence of infecting
Heme Oxygenase: Structure, Function & Pathogenesis
Novel therapeutic strategies such as modulation of dendritic cell and T cell functions have shown great potential in clinical transplantation. HLA-G is a molecule that plays a significant role in establishing complex mechanisms to protect semi-
Aberrant somitogenesis leads to birth defects in humans. Later in life abnormal Notch, Wnt or Fgf signaling causes malignancies such as colon cancer and leukemia. We use zebrafish as a tractable, relatively inexpensive vertebrate model system t
Genetic Analysis of the Zebrafish Somitogenesis Oscillator
We propose here a series of studies that will greatly advance the understanding of the regulation of a particular ion channel protein, the large-conductance calcium-activated potassium channel, or BK channel, which plays a vital role in the reg
Examining the Gating Mechanisms of the Large-Conductance Ca2+ -activated K+Channel
PUBLIC HEALTH AND ENVIRONMENT, COLORADO DEPARTMENT OF
Funding for remedial design and construction costs at the Summitville Superfund project.
ARRA Hazardous Substances Response Trust Fund
ERP - OGS PAVEMENT REHABILITATION, RTS 5S & 29
ERP - PAVEMENT REHABILITATION ONEIDA COUNTY
ERP -PAVEMENT REHABILITATION LOCAL (AMS,GLOV,JOHNST,L/FALLS)
PM PAVEMENT OGS: RT 67, MONTGOMERY COUNTY
The ARRA funding assists the State of Ohio by subsidizing its Clean Water State Revolving Fund for the financing and construction of wastewater treatment facilities and associated infrastructure, green infrastructure, and non-point source proje
NEW JERSEY DEPARTMENT OF ENVIRONMENTAL PROTECTION
New Jersey received the ARRA grant from EPA for the Clean Water State Revolving Fund (CWSRF) to fund water quality projects in New Jersey while aiding in the economic recovery within the state. Forty-four ARRA CWSRF loans were awarded. In the f
Municipal Finance & Construction Element
This agreement provides funding under the American Recovery and Reinvestment Act of 2009 to the Commonwealth of Puerto Rico to capitalize its revolving loan fund for the financing for the construction of wastewater treatment facilities and asso
2009 ARRA Capitalization Grant for PREQB-CWSRF
ENVIRONMENT AND CONSERVATION, TENNESSEE DEPARTMENT OF
These funds will be utilized to assist the State of Tennessee capitalize its revolving loan fund for the financing of construction of wastewater treatment facilities and associated infrastructure, green infrastructure, nonpoint source projects,
Capitalization Grants for State Revolving Fund
The CWSRF ARRA Grants will provide funding to rural communities  for the construction of wastewater treatment facilities which will protect water quality in New Mexico
NATURAL RESOURCES, MISSOURI DEPARTMENT OF
This funding is for the construction of wastewater treatment facilities and associated infrastructure, green infrastructure, nonpoint source projects, and program administration.
This award will be used for salary and benefits to support one post-doctoral fellow.  Since the award of this supplement application was notified on 09/14/2009, the post-doctoral fellow has been hired to carry out experiments proposed in the su
Regulation of apoptosis by Bcl-XL, Bak and Bax
Dr. Simen is a clinical psychiatrist with a Ph.D. degree in Neurobiology. His career goals are to become an independent investigator in the Aging field, with a focus on how genomic changes that occur with age influence risk for cognitive and be
Epigenetic Factors in vulnerability to Aging and Stress
Organic dust exposure is an important occupational hazard for persons who work in swine confinement barns. Organic dust exposure to naive individuals results in an intense systemic and pulmonary inflammatory response that attenuates over time,
Chronic Innate Immune Adaptation to Organic Dust
Posterior polymorphous corneal dystrophy (PPCD, MIM #122000) is a dominantly inherited corneal endothelial dystrophy associated with a varied phenotype, ranging from symptomatic corneal endothelial changes to glaucoma and progressive corneal ed
This award of $ 100,000 was for partial funding for a Bruker Biospin 800 MHz solution NMR spectrometer costing $1,050,000. The spectrometer dramatically enhance access to high-field NMR spectrometer time urgently needed for studies of large pro
NMR and Computational Studies of Biomolecules
The Center for Health Improvement of Minority Elderly  This purpose of this administrative supplement request from the Resource Centers for Minority Aging Research (RCMAR) National Coordinating Center at UCLA (CC) is to provide funding to minor
THE CENTER FOR HEALTH IMPROVEMENT OF MINORITY ELDERLY
Data from our laboratory has shown that gamma-amino butyric acid (GABA) inhibitory tone within a crucial glucose sensing region of the brain, the ventromedial hypothalamus (VMH), plays an important role in modulating the magnitude of glucose co
Support to provide shared resources for research activities at the Jules Stein Eye Institute at the University of California, Los Angeles.
JULES STEIN EYE INSTITUTE CORE GRANT FOR VISION RESEARCH
CENTER FOR NEUROVISCERAL SCIENCES & WOMEN'S HEALTH  The Center for Neurovisceral Sciences & Women's Health is composed of a cohesive group of clinical investigators and basic scientists with strong independent grant-supported research programs
CENTER FOR NEUROVISCERAL SCIENCES & WOMEN'S HEALTH
The award supports work for a proposed research project: “Using a population-cased approach to investigate whether genetic inflammation markers and/or use of nonsteroidal anti-inflammatory drugs NSAIDS) predicts motor and non-motor progressio
THE UCLA UDALL PARKINSON DISEASE CENTER OF EXCELLENCE
This grant, a summer supplement to the project - Systems-Based Consortium for Organ Design and Engineering: Polony Multiplex Analysis of Gene Expression Technology Development,provided a summer research experience for 1 science educator and 1 c
SysCODE: PMAGE Technology Development (10 of 10)
The long-term goal of the current project (2 R15 GM069562-02) is to develop a fundamental understanding of the regulatory control of terpene production in Artemisia annua so that in planta metabolic manipulation of terpenoid biosynthesis can ev
Artemisinin Biosynthesis: Control of Transcription
Chemosensory Perception and Psychophysics in the Aged- Administrative Supplement to parent grant 55736A 'Chemosensory Perception and Psychophysics in the Aged.  Funding is provided under ARRA supplement to support undergraduate research assista
ARRA: Chemosensory Perception and Psychophysics in the Aged- Administrative Supplement
We respectfully request administrative supplemental support to provide summer research experiences for students and science educators. Specifically, we plan to employ one pre-baccalaureate undergraduate and one post- baccalaureate graduate stud
Transcription Regulation in the Aging Heart
Project Narrative Herpes simplex virus-2 (HSV-2), a causative agent of genital herpes, is a highly prevalent (45 million in the USA alone) sexually transmitted infection. Once acquired, HSV-2 causes a life-long incurable debilitating disease fo
Immune induction to genital herpes simplex 2
Herpes simplex virus (HSV) is a common and significant pathogen which causes a variety of disease processes in humans, ranging from cold and genital sores to blindness. The lifecycle of HSV has two distinct phases: lytic and latent infections.
Viral and host responses to HSV infection
Title: 'Gender Bias in Lupus: Contribution of Sex Chromosomes' Autoimmune diseases that cause chronic damage to almost every organ in the body are more common in women than men. For example, systemic lupus erythematosus (SLE) is 9-times more co
GENDER BIAS IN LUPUS: CONTRIBUTION OF SEX CHROMOSOMES
Our parent R01 grant (5R01CA109345-05), which will end on June 30, 2009, proposes to investigate the molecular mechanism by which retinoid X receptor-alpha (RXR?) acts in the cytoplasm in response to 15-Deoxy-?12,14-prostaglandin J2 (15d-PGJ2)
Overall purpose:The principal purpose of this supplemental proposal is to develop novel derivatizing agents for labile keto and aldehydic functional groups that will facilitate their mass spectrometric analysis. Metabolites with these functiona
Biochemical Mechanisms of SeAnticancer Activity in Lung
The present administrative supplement will allow us TO HIRE VALERIE GORDON AND KEEP MARY MORGAN TAYLOR IN THE LAB FOR ONE MORE YEAR before they each join graduate school. Valerie has worked in the lab as an undergraduate student for the past 3
The 2009 Recovery Act awarded funding to 13 municipal law enforcement agencies within Milwaukee County.  These funds being used to enhance public safety throughout Milwaukee County.
Enhancing Public Safety in Milwaukee county
Community Service Work Crew Oversight and Group/Individual Mental Health Programming.
Purchase of 30 narrowband compatible portable radios for the Ellensburg Police Department in anticipation of the mandatory narrowband requirement effective in 2012, as well as an evidence management system for the Kittitas County Sheriff's Offi
JAG funds were utilized to purchase a patrol vehicle for use by the Community Oriented Policing Unit and contractual support for our existing data management system which is vital to the daily operations of our COP unit as well as other divisio
The Justice Assistance Grant (JAG) Program funded under the Recovery Act is the primary provider of federal criminal justice funding to state and local jurisdictions. Recovery JAG funds support all components of the criminal justice system
BIA FY 09 Recovery Act Edward Byrne Memorial Justice Assistance Grant Program Local Solicitation
Technology Improvement Programs/Maintenance Contracts and Law Enforcement equipment.
Purpose was to hire a 30 hour a week officer for two years to allow department to continue level of service and allow for officer training, to add radio channels to existing communications channel to allow greater access and interoperability, t
ARRA Award for City of Calais, Town of Machias and the County of Washington all in Maine.
Fairmont-Marion County Local Law Enforcement Recovery Program - Law Enforcement Equipment Purchase Grant
Fairmont-Marion County Local Law Enforcement Recovery Program
The City of Manchester is applying for the FY 09 Recovery Act Edward Bryne Memorial Justice Assistance Grant (JAG) Program: Local Solicitation as the fiscal agent for the allocated $1,405,199 for City of Manchester, City of Nashua, Town of Amhe
City of Manchester Recovery Act JAG Project
This program supports law enforcement efforts in solving or reducing crimes and prompting community and justice assistance efforts in areas including low frequency communications, audio and video enhancements for improved criminal justice syste
BJA FY 09 Recovery Act Edward Bryne Memorial Justice Assistance Grant Program Local Solicitation
The City of Junction City, Kansas Police Department 2009 Criminal Records System Improvement Project seeks to improve and enhance their shared records management system / 911 dispatch center and jail system.  Geary County, Kansas is served by t
2009 JAG Criminal Records System Improvement Project
This award provides for the purchase of the following equipment:  Police Radio System Upgrade; Crowd Control Safety Equipment; Tactical Radio Equipment; Tactical Rifle Sights; GPS Surveillance/Tracking Device; Upgrade Electronic Audio/Video Mon
Chico Police Department Service Enhancement Project
The South Miami Police Department-Patrol Unit will purchase ten laptop computers with software and one police vehicle.  These purchases will allow for retention of jobs.
BJA FY 09 Recovery Act Edward Byrne Memorial Justice Assistance Program Local Solicitation
$29,100 awarded for the purchase of Eotech rifle sites and night vision systems to be utilized by the Emergency Response Team.  The team is a tactical team the provides support for all of Franklin County during the event of critical incidents a
The Dallas Police Department is using this grant money to improve and advance the Department through better equipment. The department is establishing a K-9 program and training offincer on the new equipment and K-9.
Equipment and Technology improvement program
Upgrade technology within the City of Bunnell Police Department.
Intake Assessment Officer for Campbell County, TN, Juvenile Courts.
BJA FY 09 Recovery Act Edward Byrne Memorial Justice Assistance Grant
Grant purchased 2 patrol vehicles and funded overtime for drug enforcement
Two boroughs within Franklin County, PA are allotted JAG Formula Program funds.  The boroughs of Chambersburg and Waynesboro are allocated $89,098 and $15,262 respectively for a total allocation of $104,360.  As a disparate allocation jurisdict
Enhancing Law Enforcement in Franklin County, PA
Berks County, the city of Reading, the borough of West Reading, and the townships of Bern, Cumru, Exeter, and Muhlenberg will apply Recovery Act JAG funding toward multiple initiatives aimed at enhancing criminal justice services provided to th
BJA 09 Recovery Act Edward Byrne Justice Assistance Grant Program Local Solicitation
$50,521 in JAG funds has been used to advance the document imaging capabilities and communications between law enforcement and criminal justice departments.  This requires improvements to the capacity of information technology and data sharing
Document Imaging and Communications Enhancement
Officer Safety/Citizen Response Equipment Update
Officer Safety/Citizen Response Equipment Upgrade
The award is being used to purchase 50 laptops and 80 docking stations.
Oneida County and the cities of Utica and Rome will apply for fiscal year 2009 Recovery Act JAG funding towards separate initiatives aimed at increasing public safety in the community.
Recovery Act JAG Program Smith County's grant funding will be used to continue comprehensive communication connectivity with first responders, purchase of portable radios, three(3) law enforcement vehicles and specialized training. Wireless Con
FY 09 Recovery Act - Edward Byrne Memorial Justice Assistance Grant Program Local Solicitation
this is the final step in the process of closing out the grant; in that the monies granted was fully expended by June 30, 2010.  No activity to report from July 1 - December 31, 2010.
Grant award to assist local law enforcement.  General funding dollars which can be used as needed. This allowcation was originally set for overtime cost reduction, due to Marijuana enforcment, but modified to be used for any drug enforcement.
Police department operational equipment initiative
Police Department Operational Equipment Initiative
The Town of Stratford Police Department will use its award to enhance its information technology infrastructure and improve physical security at police headquarters.  The Town will purchase and install crime mapping and analysis software.  Once
FY 2009 Recovery Act Justice Assistance Grant Program- Stratford, CT Security Technology and Crime Mapping Project
Project Goals:  The Police Department's main goal is to improve the efficiency of their communications and patrol officers, while increasing the presence of the officers on the streets.  The objective of this goal is purchase laptops and air ca
The Delray Beach Police Department used its Fiscal Year 2009 Recovery Act JAG award to pay officer overtime for the Holiday Robbery Task force, purchase six patrol vehicles, and contract services for installation of driving simulators that were
The Tallapoosa Drug Court serves the addicted population in Polk and Haralson Counties.  The participants have to meet strict requirements and go through 5 phases to graduate. The program closely follows the 10 Key Components.
The Sarasota County Sheriff's Office is proposing the creation of a Pharmaceutical Diversion Investigative Unit (PDIU).  The goal of the Unit will be to reduce the number of pharmaceutical drug overdose deaths in Sarasota County.  The Unit will
Osceola County will use its Fiscal Year 2009 Recovery Act JAG award to support the following six programs. The first program, implemented by Osceola Mental Health, Inc. dba Park Place Behavioral Health, is for the expansion of the agency's Adul
The disparate jurisdictions consisting of Canyon County and the cities of Nampa and Caldwell will use their Recovery Act JAG award in the amount of $661,565 to improve the patrol car fleet by replacing several high mileage vehicles, to increase
Maintaining essential services through equipment purchases.
FY 09 RECOVERY ACT EDWARD BYRNE MEMORIAL JUSTICE ASSISTANCE GRANT PROGRAM LOCAL SOLICITATION - DRUG INVESTIGATIONS
Program Title:  BJA FY 09 Recovery Act Edward Byrne Memorial Justice Assistance Grant Program Local Solicitation;  Project Title: Voice Logging Recorder Upgrade.  The disparate jurisdiction consisting of City of Nogales and Santa Cruz County wi
JAG Stimulus Grant for the City of Shelby, County of Cleveland, and City of Kings Mountain.
The Justice Assistance Grant (JAG) Program funded under the Recovery Act is the primary provider of federal criminal justice funding to state and local jurisdictions.  Recovery JAG funds support all components of the criminal justice system,
This is for the City of Findlay Radio Interoperability Project so that the City can be on the state MARCS radio system.
City of Findlay Interoperability Project
The Yavapai County Adult Probation Department will purchase ballistic vests, as many of their current vests are in need of replacement, and printer/copiers for use in their interview rooms.  They will also pay for drug testing supplies that Pro
Investments to Increase Economic Efficiency
Investments to Increase Econominc Efficiency
American Recovery and Reinvestment Act of 2009.5
The overall purpose for this grant is to provide much needed enhancements to Klamath County Sheriff's Office Patrol and Correction Divisions and Klamath County Juvenile Division. Due to ever dwindling financial resources, both the Klamath Count
Enhancement ot Klamath County Sheriff's Office Patrol and Correction Divisions and Klamath County Juvenile Facility
Purchase of video forensics equipment and software to increase identification and arrest capabilities; purchase of speech recognition softwrae; purchase of GIS software and equipment for crime analysis; purchase of computers, laptop printers, s
Walker County/City of Huntsville Recovery Act JAG
Grant for the purchase and installation of mobile audio/video recording equipment for police patrol vehicles.
The goals of this grant continue to be:  1). The Lawton Police Department will purchase a SWAT truck, Mobile Data Terminals, a training Skid Car, underwater communication equipment, patrol rifles, radios, fingerprint imager equipment, alcohol b
FY 2009 Edward Byrne Lawton Police Department/Comanche County Equipment Purchase Plan
JAG funds will be utilized for Municipalities in Ocean County for training, personnel,equipment to enhance Law Enforcement technology in general.
JAG funds will be utilized for Municipalities in Ocean County for training,personnel,equipment to enhance Law Enforcement technology in general
The goals of this project is to seek to prevent or reduce crime and violence through the uses of automation, computers and emerging technologies to reduce the time necessary to complete routine tasks, free up personnel for more important work,
Law Enforcement: The County will be conducting overtime patrols in the city of Racine, and will purchase and equip a patrol vehicle. The Village of Caledonia will purchase light bars for it patrol vehicles. The Village of Mt. Pleasant will equi
Recovery Act Edward Byrne Memorial Justice Assistance Grant (JAG) Formula
Equipment, supplies, training and software for the assistance of law enforcement
overtime reimbursement for drug and serious related crime
Create jobs, provide for overtime costs, and support the purchasing of much needed equipment that will improve or enhance law enforcement-specific programs
Recover Act: Edward Byrne Memorial (JAG): Local Solicitaion
Rehire of Sworn Law Enforcement Personnel
The St Landry Parish Sheriff's Department will utilize the 2009 Recovery JAG funds to enhance their analytical abilities by hiring an analyst.  The purposes of the analyst will be to work to identify and correct organizational needs within the
FY 2009 ARRA Recovery Justice Assistance Grant Program
Fy 09 Recovery Act Local Youth Mentoring Initiative
This award provided summer salary support for 2 undergraduate researchers who previously volunteered in the PIs laboratory.  Both UCLA undergraduates are pre-med majors and are currently in the process of applying for admission to major medical
THE IMPACT OF HEAT SHOCK PROTINE EXPRESSION ON INFLAMMATION AND INSULIN ACTION
The long-term objectives of these proposals are to better understand the biochemical and biophysical changes that occur in the human lens with aging, and which ultimately lead to cataract. The proposed studies will focus on alpha-crystallin. In
Aminoacyl-tRNAs provide the interface between genetic information encoded in the DNA sequence of a gene and the amino acid sequence of the corresponding protein. In this supplement three important aspects of aminoacyl-tRNA formation are address
A tremendous amount of cellular metabolism is dedicated to producing ribosomes, the large ribonucleoprotein factories of protein synthesis responsible for translating mRNAs into proteins. Ribosomes are synthesized in the nucleolus following a s
Assembly, Localization and Function of the U3 snRNP
mutants will be carried out by C. Kisker and S. Doublie as our studies draw heavily on knowledge of the crystal structures of RB69 pol complexes. Since RB69 pol is a member of the B family (which includes two human replicative DNA polymerases,
Molecular Biology and structure of DNA Replicase
The long-term goal of this project is to understand the molecular mechanism by which cells acquire the essential trace metal copper. Towards this goal, we propose an integrated approach that combines electron crystallography, scanning mutagenes
Structure and Function of Copper Transporters
We requested an administrative supplement to purchase (1) an HPLC system with supporting computers and columns and (2) a high pressure cell homogenizer to augment the work supported by R01GM062328. The award is final and the equipment was purch
Continued support is requested for our investigation of integrin-filamin interactions and their roles in adhesion signaling and cell migration. Integrins are transmembrane receptors that support cell adhesion and migration. They play essential
Integrin-Filamin Interactions in migration and signaling
The protein-protein docking problem is one of the focal points of activity in computational structural biology. The 3D structure of a protein-protein complex, generally, is more difficult to determine experimentally than the structure of an in
Integrated Resource for Protein Recognition Studies
This award is part of the ENCODE consortium and aims to 1) identify novel long-range acting gene regulatory elements and 2) to link these elements to specific (distant) target genes.  This grant focuses on 1% of the human genome that was select
Structural Annotation of the Human Genome
Hypersensitivity pneumonitis (HP) or extrinsic allergic alveolitis is an interstitial lung disease that develops following repeated exposure to inhaled environmental antigens.  The disease is characterized by alveolitis and granuloma formation
The Role of Neutrophils in Hypersensitivity Pneumonitis
Central apnea and dysrhythmia is typical for sleep apnea and Rett Syndrome patients as well as Sudden Infant Death Syndrome victims. Since respiratory pacemakers are likely to underlie respiratory rhythmogenesis (Pena et al. 2004), investigatin
Background Sodium Currents in Respitory Pacemakers
GTP cyclohydrolase I (GCH-1) is the rate-limiting enzyme in the biosynthesis of BH4, an essential cofactor for endothelial nitric oxide synthase (NOS3). BH4 depletion uncouples NOS activity, which is characterized by superoxide anion generation
Characterizing the role of CREB in leukemogenesis and normal myelopoiesis  The overall purpose of this project is to characterize the mechanism by which CREB regulates normal and abnormal myelopoiesis.  Expected outcomes: CREB increases short-t
MOLECULAR AND CELLULAR CHARACTERIZATION OF MYELOPROLIFERATIVE DISEASE
We requested stimulus funds to increase the pace of enrollment, data analysis and dissemination of our study to improve the quality of communication between physicians and parents after newborn genetic screening. Many psychosocial complications
Supplement: Improvement of Communication Process and Outcomes After Newborn Genetic Screening
Autophagy is a process that is involved in degradation of long-lived proteins and removal of damaged organelles.  Autophagy is generally thought of as a survival process that is upregulated by the cells during periods of starvations, but recent
ARRA: Role of Bnip3 in Myocardial Ischemia/Reperfusion Supplement for Aficial
Our parent grant aims to understand the biological role and therapeutic potential of S100A1, which is released from injured cardiomycocytes, in the course of cardiac inflammation and mycardial regeneration after ischemic damage.  The aim of the
S100A1: A novel modulator of myocardial infact inflammation and regeneration
Tourette Syndrome (TS) is a neurological disorder characterized by persistent motor and vocal tics. Tics can be brief, rapid and darting movements of the face, shoulders, and extremities or more complex and purposeful in appearance. Vocal tics
Behavior Therapy for Adults with Tourette Syndrome
The contributions of anatomy and biophysical properties to the function of neurons and neural circuits are best understood with the aid of computer simulations. NEURON, a program which we have developed and provide freely for Mac OS X, MS Windo
Computer Methods for Physiological Problems
The proposal here addresses two related questions that are direct extensions of our parent grant on MCH neurons. Despite many papers on the role of MCH in energy homeostasis and emotional states, and the expression of MCH axons and receptors de
Respose Properties of Hypothalamic MCH Neurons
The project involves the assessment of motor and executive dysfunction in three mouse models of Parkinson's disease. Upon establishing baseline performance, mice will be treated with an rAAVmediated siRNA construct to silence GD3 synthase (GD3S
GD3S knockdown to improve cognitive and motor defects in models of parkinsonism
The goal of this R01 (NS41574) is to understand the mechanisms that lead to neuronal dysfunction in HD, an inherited, progressive neurological disorder characterized by abnormal dance-like movements (chorea), cognitive disturbances, and disorde
PATHOPHYSIOLOGY OF TRANSGENIC MOUSE MODELS OF HUNTINGTON'S DISEASE
A growing body of experimental evidence suggests that hemoglobin release from lysing erythrocytes may contribute to oxidative injury to tissue surrounding a hematoma. Prior studies have demonstrated that hemoglobin toxicity is mediated by trans
Effect of Inducible Antioxidants on Hemoglobin Toxicity
Olfactory ensheathing glia (OEG) transplantation was combined with intensive treadmill step training to optimize the maximum functional recovery in adult rats following a complete spinal cord transection (spinal rats). We conducted many more pr
COMBINED OEG TRANSPLANTATION AND STEP TRAINING PROMOTE REGENERATION IN ADULT SCI
Our broad research aim is to elucidate the mechanisms through which the basement membrane (BM) directs epithelial architecture and function, and to identify the alterations in cell-BM communications that contribute to cancer progression. Signal
Dystroglycan in Epithelial Architecture and Function
Programmed cell death plays an important role during animal development, and defects in this process result in a variety of human disorders including cancer and autoimmunity.  Apoptosis and autophagic cell death are the two most prominent morph
Genetic Regulation of Autophagic Cell Death
Math1, a transcription factor, is one of the critical genes for the formation of hair cells (HC) in the inner ear as shown by its loss in Math1 knockout mice.  However, we recently demonstrated that genotypically Math1-null hair cells are able
Analysis of surviving math1-null hair cells in the inner ear of chimeric mice
The aim of the parent grant proposal was to clone the gene responsible for a new mouse craniofacial mutation, Hollow Ear (or Hol), identified by ENU mutagenesis. The Hol mutation phenocopies the Tbx1-deficient mouse mutant, but does not map to
The work involves mouse embryonic stem cells and human embryonic stem cells obtained from federally-approved cell lines. The broad objective of this proposal is to enable embryonic stem cells (ESCs) to specifically recognize and bind to infarct
Making Embryonic Stem Cells Infarct Avid
What is the Problem: The United States has become largely dependent on a foreign workforce. By 2025, more than 50% of all American high school (HS) students will be the children of today?s American minorities?of those, 75% will be Hispanic. Yet
We seek continuation of the University of Kansas (KU) IMSD program, a program whose underrepresented scholars are enrolling in graduate programs in the sciences at more than twice the national average, and that has succeeded in bringing five Am
MBRS IMSD Program at the University of Kansas
University of Nebraska Medical Center (UNMC) will partner with the Aberdeen Area Tribal Chairmen's Health Board (AATCHB), with tribal schools in Nebraska and South Dakota, and with an urban elementary school to develop, implement and evaluate h
Breaking Barriers: Science Education in Native American Communities
Specific Aims and Objectives The specific aims of this administrative supplement are to improve the management and programmatic aspects of the Cal State LA RISE Program. Through these improvements we will increase the pace of research training
Research Initiative for Scientific Enhancement (RISE)
This award provides additional funding for 2R37AA014372-06A1 for the purchase of equipment only and will have no impact on jobs being created or maintained.  More than 2 million Americans suffer from alcohol-related liver disease and about 30,0
Hepatitis B is a major global health problem. About 350 million chronically infected people are at high risk for cirrhosis of the liver and liver cancer, resulting in appoximately a million deaths annually. Current vaccines command a $1 billion
The award will create a position in the Department of Microbiology, Immunology and Molecular Genetics for hiring either a postdoctoral researcher or a highly qualified Staff Research Associate to contribute to the research program on Trypanosom
REGULATION OF TRYPANOSOME DNA REPLICATION
Evidence from different disciplines suggests that acute and chronic stress-related mechanisms play an important role in the development of and the chronic, relapsing nature of addiction. These brain stress systems, including the central and per
Norepinephrine Transporter Imaging in Alcohol Dependence and Obesity (8 of 14) (IRC$)
Training in molecular biotechnology is essential for an expanding list of disciplines that have found modern biology-based skills of critical importance in pursuing research goals in areas ranging from biochemistry to chemical engineering to pl
Graduate Training in Molecular Biotechnology at NC State
This proposal requests support for predoctoral training in Pharmacological Sciences at the Weill Graduate School of Medical Sciences (WGSMC). The Training Program in Pharmacological Sciences at WGSMS is inter-departmental and inter-institutiona
Predoctoral Training in Pharmacological Sciences
Award Title:  HIV-1 Therapy with CCR5 mAb PRO 140 Award Description:  PRO 140 is a humanized monoclonal antibody that binds to CCR5, a co-receptor that is the principal molecular portal used by HIV to enter and infect immune system cells.  Some
The pattern of activity in the circuits of the brain and their experience-dependent changes underlie the processing of sensory information, perception, and motor control. Much has been learned about the anatomical wiring of brain circuits and a
Scan of Protein space for optical voltage probes
Remove and replace lights with energy efficient lights at Pendills Creek Fish Hatchery
The project will reconstruct the deteriorated gate apron pavement, including all associated lighting, hydrant system, jet bridge foundations, drainage, pavement and sub-grade preparation.
Devils Lake - ND 20 from US 2 to (RP 104.408) Urban Limits (exception 3rd St NW  to 6th St NE)
This project consists of the reconstruction of the existing airport parking apron areas, and drainage improvements.  The area consists of approximately 1,200,000 square feet.  Project will include removal of existing pavement and aircraft tie-d
Compton/Woodley Airport Pavement Rehabilitation Project
Airport Development to construct Aircraft Rescue and Fire Fighting Building
ARRA-AIP Relocation of ARFF Firestation at LAX
BOARD OF PORT COMMISSIONERS OF THE PORT OF OAKLAND
As per OMBs last guidance, we can no longer use 'Airport Development' as the award description. This project involves the reconstruction of pavement at Taxilane Sierra and the adjacent aircraft parking apron.
Rehabilitation of Apron, South Field, OIA
The award was for development of the Charles M. Schulz-Sonoma County Airport.  This included expanding and upgrading the airport terminal to better serve our traveling public.  In August 2010, an amendment was awarded that covered the cost of w
Highway Infrastructure Investment Grant: Rural Areas with Population under 5k
Rehabilitation of Apron Concourses D, E, and F. Project  includes demolition and replacement of damaged apron concrete slabs, cleaning and re-sealing all existing joints, grinding and re-striping of apron markings, milling and overlaying asphal
Rehabilitation of  Apron Concourse D, E, and F
RT.90\LITTLE SALMON CREEK & PAINES CREEK
Construction of an Aircraft Rescue and Fire Fighting Building, needed for Part 139 compliance at the St. Louis Downtown Airport, Sauget, Illinois.
St. Louis Downtown Airport, CPS-3905-ARRA
Airport Development:Acquire Safety Equipment and/or Fencing
Increase Height of Perimeter Wildlife Fence from 8 Feet to 11 Feet  (approximately 30,000 lft); EQ SA RF Acquire Safety Equipment and/or Fencing
The goal of the project is to hire a full-time civilian Evidence Technician to shift appropriate workload within the Detective Division from sworn personnel to civilian personnel.  The Winnebago County Sheriff's Office currently utilizes a dete
Hiring of Civilian Staff in Law Enforcement and Public Safety-Related Agencies
JUDICIARY COURTS OF THE STATE OF COLORADO
The Colorado Judicial Department applied for and received $2,701,012 in grant funding from the Recovery Act: Edward Byrne Memorial Competitive Grant under Category VII: Supporting Problem-Solving Courts to support the Colorado Drug Court and DU
Colorado Adult Drug Court and DUI Court Statewide Expansion Project
The Union County Sheriff's Office will re-employ a Records Manager laid off in March 2009 and purchase computer equipment for the Records Manager. The equipment will aid the Records Manager in producing analytical, meaningful, and visually info
The Strengthening Community Supervision in Florida Program
JUDICIARY COURTS OF THE STATE OF NEW JERSEY
New Jersey Probation Specialized Mental Health Caseload Expansion.  We will utilize FY09 Byrne Recovery Act funds to hire 30 probation officers to establish adult mental health caseloads statewide, establish collaborative partnerships between p
New Jersey Probation-Specialized Mental Health Caseload Expansion
CHILDREN'S HOSPITAL MEDICAL CENTER OF AKRON
Expansion of C.A.R.E. Center Services to Include Trauma Invervention Services for Child Crime Victims
The police department will fund two dispatcher positions, two animal control officers, and an evidence technician.  Hiring these personnel would bring the dispatch, animal control, and the evidence divisions up to full staff as originally plann
FY 2009 Recovery Act Byrne Competitive Grant Program
NATIONAL ASSOCIATION OF POLICE ATHLETIC/ACTIVITIES LEAGUES, INC.
National PAL Mentoring Program: Initiate community-based youth mentoring programs that strengthen and expand mentoring and dropout prevention services to at-risk/high-risk populations.
To provide national training and technical assistance to practitioners in federal, state, and local criminal justice and corrections agencies, along with other reentry practitioners, on fatherhood programming as a tool to increase employment an
Enhancing Rural Corrections, Detention, & Jail Operations in the amount of $478,764 for Tillamook County. Funding provides the retention of one position and maintian three Corrections Deputies. Maintaining minimum staffing levels in the jail.
Retention of Certified Corrections Deputies.
LINCOLN & SAGADAHOC MULTICOUNTY JAIL AUTHORITY
The project will enhance pre-trial services through a validated risk assessment.
Enhancing pre-trial services through validated risk assessment
Ashland Police Department Information Sharing.  Key deliverable s for this project are as follows: purchase of a records management system, dispatch recording system and a live scan fingerprint system. Plus the creation a of new records manager
Ashland Police Department Information Sharing
Under Category 1, Tillamook County, in conjunction with the North Coast Regional Task Force (NCRTF), will receive a $1,148,224 grant to increase illegal drug intelligence sharing, collaborate in investigations involving illegal drugs, and prote
1.  Combat rural crime 2.  Improve rural law enforcement investigations to reduce drug trafficking and related crimes
BJA FY 2009 Recovery Act Assistance to Rural Law Enforcement to Combat Crime and Drugs:  Improving Rural Law Enforcement Investigations This grant award has enabled us to hire a full-time Narcotics Investigator, along with specialized equipment
Powhatan County Improvements to Narcotics Investigations
The overall goal of the project is to improve drug crime investigations.  The Paintsville Police Department will hire a police officer and a prosecutor for two years to focus on investigating, prosecuting, and reducing drug-related crimes.  The
CRIMINAL JUSTICE INFORMATION CENTER, ALABAMA
The Alabama Criminal Justice Information Center (ACJIC) plans to provide NCIC access to all rural jurisdictions in Alabama.  Plans include hiring one new field agent to cover ACJIC Region 6.  Also, half of a current staff member's time is cover
Providing NCIC Access to Rural Areas in Alabama
The Guam Criminal Justice Information Sharing Improvement Project will assist Guam's National Criminal Information Center (NCIC) Unit in providing timely criminal justice information to various databases, including NCIC 2000, the Integrated Aut
FY2009 Recovery Act Guam Criminal Justice Information Sharing Improvement Project
The award will establish a statewide strike force that targets drug trafficking organizations operating in rural areas.  The grant will fund 5 full time employees
This grant is designed to have two detectives assigned to investigate repeat offenders.  The detectives primary responsibility is to review all cases and identify repeat offenders, with emphasis on violent repeat offenders. The detectives are t
Create a single point of contact to the juvenile justice system in Crook County, Wyoming and to provide diversion services and enhanced probation services to youth.
Crook County Community Juvenile Services
The Bureau of Justice Assistance (BJA) solicits applications for initiatives which assist law enforcement in rural states and rural areas.  The program helps rural states and rural areas to prevent and combat crime, especially drug-related crim
The goal of this project is to expand the investigation of drug-related and other crimes by the Police Department of the West Virginia University Institute of Technology.  The Administrative Secretary position was once again filled at the begin
Enhancing Investigation of Drug-Related and Other Crimes
In the spirit of the ARRA of 2009, this project will:  1) Create jobs, 2) continue and enhance public and private sector information sharing partnerships, and 3) enhance criminal justice information sharing for rural law enforcement agencies.
Nebraska Facilitating Rural Justice Information Sharing Program
Perserving Community Based Corrections jobs in Northeast Iowa.
It is the goal of this project to hire two (2) Records Officers/Criminal Analysts, positions that would not otherwise be created due to Stevens County’s economically distressed condition.  These positions will facilitate and improve the shari
Enhancing a multi-jurisdictional information sharing system
Ehancing Rural Corrections, Detention & Jail Operations
Assistance to Rural Law Enforcement to Combat Crime and Drugs Program, administered by BJA, helps rural areas prevent and combat crime, especially drug-related, and provides for national support efforts, including training and technical assista
Drug Interdiction Officers Corridor Patrol
Recovery Act - OVC FY09 VOCA Victim Compensation Formula Grant Program.  This program reimburses victims of crime for costs incurred as a direct result of their victimization, including medical, mental health, lost wages, loss of support, and o
Recovery Act - OVC FY09 Victim Compensation Formula Grant Program
This grant provides funds from the Recovery Act to enhance State victim compensation payments to eligible crime vicitms.
RECOVERY ACT OVC FY 09 VOCA VICTIMS COMPENSATION FORMULA GRA
Pennsylvania Commission on Crime and Delinquency
The Recovery Act Compensation Grant provides the State of Connecticut Judicial Branch, Office of Victim Services with additional resources to provide financial compensation to victims, or their family members, who were injured, or killed, as a
Recovery Act - OVC FY 09 VOCA Compensation Formula Grant Program
Recovery Act-OVC FY09 VOCA Victim Compensation Formula Grant Program
The purpose of this program is to provide compensation for economic losses sustained by persons who are injured in Oklahoma as a result of criminally injurious conduct. It is the mission of this program to provide statutory benefits to eligible
Bureau of Alcohol, Tobacco, Firearms and Explosives
The U.S. Department of Justice, Office of Justice Programs awarded funds under the FY 09 Recovery Act-Victims of Crime Act (VOCA) Victim Compensation Formula to the Virgin Islands Department of Human Services.
Recovery Act - VOCA Victims Compensation Formula grant to support protection and assistance to crime victims and members of their immediate families by implementing the rights of such persons and by lessening the financial burden placed upon vi
PUBLIC SAFETY & CORRECTIONAL SERVICES, MD DEPT OF
Maryland's Criminal Injuries Compensation Board (CICB) provides assistance to innocent victims of crime who have suffered a physical injury and sustained a financial loss. This grant supplements our annual formula grant that reimburses Maryland
FY 09 Recovery Act - Victims of Crime Act (VOCA) Victim Compensation Formula Grant Program
Recovery Act - OVC FY2009 VOCA Assistance Formula  Grant Program - Create, sustain and increase funds for programs that address victims of violent crimes.
Recovery Act - OVC FY2009 VOCA Assistance Formula  Grant Program -
VOCA Recovery Act funds are being used to support 16 different projects throughout the state of Wisconsin.  Two projects support Domestic Violence Child Advocates that provide supportive services to children who have witnessed domestic violence
ARRA VOCA Victim Assistance Formula Grant Program
This award provides direct care services and support to crime victims of child abuse, sexual assault, domestic violence and the underserved population of victims.
This grant award provides funds from the American Recovery and Reinvestment Act of 2009 (the Recovery Act) to enhance crime victim services in the State. The Recovery Act - OVC FY 09 Victims of Crimes Act (VOCA) Victim Assistance Formula Grant
Recovery Act - OVC FY 09 VOCA Victim Assistance Formula Grant Program
HEALTH AND HUMAN SERVICES, NEVADA DEPARTMENT OF
Awards have been made to 14 programs across the state.  Projects include: bilingual counseling for victims of child physical abuse; counseling and case management services to youth that have been victims of gang violence; support services to ch
LAW & PUBLIC SAFETY, NEW JERSEY DEPARTMENT OF
Recovery Act funds will be used to support services to crime victims.  These services include efforts that: (1) respond to the emotional and physical needs  of crime victims; (2) assist crime victims to stabilize their lives after a victimizati
The primary goal is to collect baseline data about the habits and patterns of Internet media usage by juveniles so that law enforcement can better prepare themselves for preventative measures and strategies for prevention of crimes. Secondary g
OJJDP FY 09 Recovery Act Internet Crimes Against Children Research Grants
ICAC Task Force; Fresno County-CA  To prevent and reduce criminal behavior associated with child Exploitation via the Internet by online child predators.  Increase ICAC personnel. Increase proactive investigations. Reduce forensic backlog.  Pro
The City of San Jose (CA) ICAC Task Force plans to create two positions, a Forensic Civilian Investigator and an Analyst, to provide forensic investigations, statistics, and reports for the ICAC program.
The Cook County ICAC Task Force ('Task Force') focuses its efforts in the region of Cook County, Illinois, which includes the City of Chicago and 119 suburban towns and villages.  With a population of more than 5.3 million persons, Cook County
The overall purpose of the grant is to create four new job positions at the Georgia Internet Crimes Against Children Task Force. These positions will consist of one Secretary 3 that will assist with the administrative duties of the task force a
OJJDP FU 09 Recovery Act Internet Crimes Against Children Task Force Program Grants/Georgia Internet Crimes Against Children Task Force
Goals of the grant include hiring and training a new Computer Forensic Examiner to work at the RCFL, to assist in the backlog of forensic exams;  provide financial support to the ICAC affiliates at Utah County Sheriff's Office, Weber County She
This project involves the development of communications and signal processing algorithms and to support the reuse of the LoCosto quad-band GSM-850 band that is based on Texas Instruments Digital Radio Processor technology.
Realization of a Software-defined Emergency Radio
The primary question in geographic profiling is, given the locations of a series of crimes committed by the same serial offender, to estimate the location of that offender's anchor point. In previous work work for the NIJ we have developed a ne
FY 09 RECOVERY ACT COMBATING CRIMINAL NARCOTICS ACTIVITY STEMMING FROM THE SOUTHERN BORDER OF THE UNITED STATES
ARRA Renovation of Correctional Facility
FY09 Recovery Act Correctional Facility Renovation
Chippewa Cree Tribal Justice Center Construction Project
Renovation of the White Mountain Apache Tribe's Detention Center.
Renovation of the White Mountain Apache Tribe's Adult and Juvenile Detention Center
FY 2009 Recovery Act JAG Program. This program is designed to support the overall goals of the Edward Byrne Justice Assistance Grant (JAG) program, with special attention towards the creation and preservation of jobs.  The Byrne JAG program is
American Recovery and Reinvestment Act of 2009 (BJA Byrne JAG) (Public Law 115-5) (The Recovery Act) and by 42 U.S.C. 3750-3758. The Federal award number allocating these funds to the state of Louisiana, via the Louisiana Commission on Law Enfo
Recovery Act FY 09 Edward Byrne Justice Assistance Grant (JAG) Program
These federal funds may be used to provide funding to state agencies and local units of government, and private not-for-profit organizations, for the implementation of: law enforcement programs; prosecution and court programs; prevention and ed
FY2009 Recovery Act Justice Assistance Grant Program
The North Dakota Office of Attorney General, Bureau of Criminal Investigation (BCI), is the State Administering Agency for the JAG Stimulus funding.  The Drug and Violent Crime Policy Board (Board), which oversees the use of the JAG funding, de
FY09 Recovery Act Edward Byrne Justice Assistance Grant Program: State Solicitation
The State of South Dakota, Office of the Governor, Attorney General’s Office, will utilize its Fiscal Year 2009 Recovery Act Justice Assistance Grant Program award in the amount of $3,193,114 to assist state and local efforts to prevent and r
U.S. Department of Justice Office for Victims of Crime FY 2009 Recovery Act - National Field-Generated Training, Technical Assistance, and Demonstration Projects  Through this project, the Stalking Resource Center at the National Center for Vic
Use of Technology to Stalk Training Delivery
The grant funds were utilized to purchase in-car video cameras and automatic vehicle locators.  This equipment will enable our agency to provide our deputies with the technology needed to provide more efficient services to our community and thr
Washington Co. FY 2009 Recovery Act Justice Assistance Grant Program
These funds will utilized to acquire various specialized police equipment and technology improvement infrastructure components - i.e.  a) VBMP 6 in Orthophotography upgrade b) Peltor Headset c) Ballistic Shield d) Total Station tripod mounted m
Equipment and Technology Initiatives for the
'Bridge Construction','Demolition and reconstruction of the existing Eastern Avenue bridge over Kenilworth  Avenue.'
Eastern Ave. Bridge over Kenilworth Ave. - Bridge work
Airport Development consisting of the purchase of a new 1,500 gallon fire fighting vehicle which meets the FAA and NFPA criteria
Acquire Aircraft Rescue and Fire Fighting (ARFF) Vehicle
The C/D Apron project is a reconstruction of airfield apron pavement between Concourses C and D at Baltimore Washington International Thurgood Marshall Ariport.  It is a safety project that consists of the reconstruction of concrete pavement an
Airports have various lighting systems to promote safe operation of aircraft in and around the Airport.  A Hazard Beacon is a flashing light that is placed on a pole in an area where the ground, trees, or obstructions like radio towers may pose
As part of construction on the Prison Hill Water Tank #2 in the City and County of Carson City, Nevada the city will be constructing a new steel water tank and the demolition of the existing concrete tank.  The project will also be comprised of
Prison Hill Water Tank #2 in the City and County of Carson City, Nevada
Airport Terminal Development, Duluth International Airport, Duluth, MN. Passenger terminal replacement (Phase 1) including relocation/construction of terminal entrance road (including 4,086 feet x 24 feet roadway, 1,800 feet x 12 feet roadway,
Construct Terminal Building [2009 construction and design for 2010 construction]
PAUL MINNEAPOLIS-ST METROPOLITAN AIRPORTS COMMISSION
Airport Development: Construct Taxiway at Flying Cloud Airport (FCM)in Eden Prairie, MN.
Highway Infrastructure Investment Grant: Areas with Poplulation equal to or less than 200K
Airport Development- Grants in Aid to airports.  Prepare and overlay runway with bituminous asphalt surface.  Relocate section of Campella Drive.  Remove obstructions from runway obstacle free area.
Non primary development projects in state block grant program. Sikeston Airport
Airport Development - Grants in Aid to Airports. Pavement rehabilitation overlay.  Replace portland cement concrete apron pavement.  Crack seal and seal coat asphalt pavement.  Remark all airfield pavement.
Non primary development projects in state block grant program. Cape Girardeau Airport
Reconstruction and relocation of airport taxiways complete with LED taxiway lights, conduit and electrical can stub-outs.
Reconstructiion and Relocation of Santa Fe Airport
Construct Terminal Building, Phase II (Terminal Apron, Access Road, Utilities, and Site Work).
Southwest Oregon Regional Airport, located in North Bend Oregon,  needed to relocate the taxiway in order to accommodate the increased volume of airline traffic at the airport. The goal was to improve passenger safety by using larger aircraft.
The runway 14-32 rehabilitation project entains replacement of approximately 2,800 lineal feet by 150 feet wide of concrete pavement, re-compact sub-base in the outer 50 feet and the installation of bituminous treated base course in the outer 5
Findlay and Moon Township P.O. Box 12370
Airport Development - Rehabilitate Taxiways D,E,F & G - Allegheny County Airport - Allegheny County Airport Authority. Complete reconstruction of pavement sub-base and drainage in the reconfigured alignment of the portions of taxiways D,E,F,G.
Rehabilitate Runway 17/35 - 3,700 FT X 75 FT Overlay (Construction Only)
Rehabilitate Runway 17/35 - 3,700 FT X 75 FT Overlay (Construction Only
Airport Development: Construct New Airport
Reconstruction of runway 17L/35R; rehabilitate concrete pavement runway 17L/35R; and overlay and mark runway 17L/35R to increase and sustain economic activity for the airport and its local community
Reconstruction of runway 17L/35R; rehabilitate concrete pavement runway 17L/35R; and overlay and mark runway 17L/35R
.  Mill and overlay taxiway, repair deep cracks apply new paint.
Airport Development: Non primary development projects in state block grant program (Dodge County Airport: Rehabilitate runway)
Non primary development projects in state block grant program (Dodge County Airport: Rehabilitate runway)
Airport Development: Non primary development projects in state block grant program (Wittman Regional Airport: Rehabilitate Runway)
Non primary development projects in state block grant program (Wittman Regional Airport: Rehabilitate runway)
Runway Reconstruction Project:  Runway 10/28 is the primary runway at the Riverton Regional Airport. The existing longitudinal gradient does not comply with current FAA criteria on either end of the runway. The reconstruction of Runway 28 will
VPP-RT 79, ITHACA W CTY LN TO W BORDER OF TOMP CO, TOMP CO
The proposed International AIDS Research and Training Program is the collaborative effort of the University of South Florida (USF) and the University of Alabama at Birmingham (UAB) with Vadodara Medical College (VMC), Gujarat, India. The purpos
PROGRAM IN ADOLESCENT HIV/AIDS RESEARCH TRAINING (PAHRT)
The fundamental scientific problem we propose to address is to determine the basic neural and molecular requirements for vocal learning, which is the behavioral substrate for spoken language, one of the essential behaviors that make us human.
NIH Director's Pioneer Award  (DP1OD003312)
Abstract In the fields of biomaterials and tissue engineering, the ability to modulate cell behavior on surfaces is essential, particularly when attempting to direct cell growth and differentiation, both for in vitro engineered tissue and gener
ENGINEERING A DYNAMIC EXTRACELLULAR MATRIX MICROENVIRONMENT
The Immunization funding was awarded to build the census of the population that has been fully innoculated against diseases. The fund includes the immunization of adults and children
ARRA 317 Immunization and Vaccines for Children Grant
Sentinel event reporting award. The overall purpose of this grant is to support staffing and technological enhancements that will ensure a smooth transition from our current immunization information system to a new platform that will better sup
The activities proposed for ARRA funding are consistent with recent strategic and operational decisions made by the New York City Department of Health and Mental Hygiene (DOHMH)'s Bureau of Immunization (BOI) to improve immunization coverage ac
Supplemental Funding for Reaching More Children and Adults
The purpose of this stimulus funding is to increase the number of children and adults vaccinated against vaccine-preventable diseases in Delaware, and to improve the functionality of the Delaware immunization registry.  CDC allocated a total of
ARRA-317 IMMUNIZATION AND VACCINES FOR CHILDREN GRANTS
The goal for the use of these funds is to increase the number of children and adults vaccinated against vaccine-preventable diseases.  Grant funds will be allocated in the following manner:  School-Age Influenza Campaign:  $1,500.000 LHD Specia
American Recovery and Reinvestment Act: Immunization and Vaccines for Children Grants
Abstract:  Activities thus far have been the addition of staff to ensure data entry into the statewide immunization registry. Statewide school-based seasonal influenza clinics have been conducted and are ongoing. Two contracts have been issued
ARRA-317 Immunization and Vaccines for Children Grants
This is a Supplemental Immunization grant to 'Improve Reimbursement in Public Health Department Clinics'.  A Strategic Plan was developed to identify needed resources and remove barriers for third party reimbursement of health departments for i
Supplemental to Improve Reimbursement in Public Health Departments
This award will be used to improve data quality and enhance assessment at Immunization Information Systems (IIS) Sentinel Sites. Minnesota will expand the current sentinel site area of Hennepin County, the county seat for the city of Minneapoli
ARRA-317 IMMUNIZATION AND AVACCINES FOR CHILDREN GRANTS
COMMUNITY HEALTH, MICHIGAN DEPARTMENT OF
The operational funding earmarked is to be used for 2 specific groups: (1) Underinsured children and adolescents (aged 0-18 years) who are not eligible for vaccine provided by the federal Vaccines for Children (VFC) program, regardless of where
ARRA-317 Immunization and Vaccines for Children Grants, Supplemental Funding for Reaching More Children and Adults
Award Title: American Recovery and Reinvestment Act 317 Immunization & Vaccines for Children Grants: San Antonio Metropolitan Health District has requested funds through this supplemental application to improve and enhance the existing 317 Immu
ARRA 317 Immunization & Vaccine for Children Grants
In an enviornment of level-funded resources and increasing demand for immunizations, the Arkansas Department of Health (ADH) proposes to create a plan to bill health insurance plan for immunizations administered to fully-insured individuals.
ARRA-317 Immunization & Vaccines for Children Grants
This project seeks to develop a public health billing system plan that will seek reimbursement from private health plans whose members receive immunizations and other health services through Oklahoma's county health departments.  The desired ou
ARRA 317 Immunization and vaccines for children grants
The Louisiana Office of Public Health, Immunization Program, provides vaccinations for vaccine preventable diseases to all children and adolescents.  Many children are eligible for the vaccinations at no cost to the patient or guardian, through
Innovative Projects to Improve Reimbursement in Public Health Department Clinics - CDC-RFA-IP08-80302ARRA09
HEALTH AND SENIOR SERVICES, MISSOURI DEPARTMENT OF
ARRA provided funding to stimulate economic recovery and to reduce healthcare costs through prevention activities.  These ARRA funds will support the operations needed to deliver and account for those vaccinated.
ARRA Supplemental Funding for Reaching More Children and Adults
This grant will add functionality to the existing North Dakota Immunization Information System (NDIIS) to provide Moved or Gone Elsewhere (MOGE) patient designations, capabilities to exchange data between the NDIIS and electronic medical record
This grant will support immunization program activities in an effort to increase the number of children and adults vaccinated against vaccine-preventable diseases. Objectives for this grant are in line with the goals and objectives outlined in
Antibiotic resistance is an increasing public health problem that is associated with considerable morbidity, mortality and costs. Given the reduced pace of antibiotic discovery and the approaching demographic shift towards an increasingly aged
Epidemiology of resistant bacteria in acute-care and long-term care facilities
Mathematical Techniques for Control of Epidemic Trypanosoma cruzi Transmission (1K01AI079162). The candidate researcher is a US citizen who would otherwise be unemployed next year.
Mathematical Techniques for Control of Epidemic Trypanosoma cruzi Transmission
The AKT signaling pathway is important for the survival of multiple myeloma cells (MM). An important downstream target of AKT is the mammalian target of rapamycin (mTOR), which mediates phosphorylation of p70 and 4E-BP1, factors responsible for
Effects of mTOR inhibitors on multiple myeloma tumors
This supplemental award provides support for the salaries of two postdoctoral research fellows under the project Bone-Seeking Proteasome Inhibitors for Myeloma.
BONE-SEEKING PROTEASOME INHIBITORS FOR MYELOMA
Tumor progression toward a malignant, metastataic disease state involves complex interactions between tumor cells and the host microenvironment, including vascular endothelium. My research centers on understanding the role of EphA2 receptor tyr
The Role of EphA2 Receptor Signaling in Host-Tumor Interactions
DESCRIPTION (provided by applicant): The proposed plan for this NCI Mentored Career Development for Underrepresented Minorities K01 award is a two-year Mentored Phase, followed by a three-year Independent Phase. The Mentored Phase will provide
Regulations of Normal and Neoplastic Growth
My primary goal is to understand how mutational activation of K-RAS induces high grade dysplasia early during the malignant progression of colorectal cancer. My working hypothesis is that mutant K-RAS signals through the B-RAF kinase to suppres
Genetic and genomics analysis of Ras signing in colorectal cancer progression
Signaling by the Notch receptors has been implicated in maintenance and differentiation of the pluripotent progenitor cells in the mammalian pancreas, intestine and vasculature. Within the parent grant, we have shown that during branching morph
Notch Sigaling in Morphogenesis iof Mouse Prostate
The primary goal of this proposal is to engage fund that supports a technical assistant to work on the projects funded under an active NIH/NIDDK K01 Award (DK 075665).  The objective of the parent K01 award is to train and bridge the principal
Arterial Medial Calcification and Cell Differentiation
DESCRIPTION (provided by applicant): Gram-negative enteropathogenic bacteria, including Yersinia, Salmonella, Shigella and both enteropathogenic and enterohemorrhagic E. coli, cause a wide variety of gastero intestinal diseases in humans. All o
ROLE OF THE Y. PSEUDOTUBERCULOSIS YSCF PROTEIN IN TOXIN DELIVERY INTO HOST CELLS
The hired individual will assist with data collection, analyses, and manuscript preparation.
Media Literacy to Prevent Adolescent Smoking Initiation
The overarching goal of this proposal is to develop an innovative, comprehensive curriculum designed to increase medical students' knowledge and skills in the behavioral and social sciences (BSS) related to health. Curriculum development in thi
Behavioral & Social Sciences as Core Elements of the Medical School Curriculum
This administrative supplement to my K07 'Measuring Preference for Fertiloity in Breast Cancer for a Decision Aid' will create a fully web-based interactive decision aid for newly diagnosed breast cancer patients to make fertility preservation
MEASURING PREFERENCES FOR FERTILITY IN BREAST CANCER FOR A DECISION AID
This administrative supplement is intended to accelerate the pace of research and enhance the quality of research associated with the funded K07 entitled 'Using Tailored Email Messages to Enhance Phone Counseling at a Smoking Cessation Quitline
Using Email to Enhance Counseling Services at NCI's Smoking Cessation Quitline
The overall goal of the proposed administrative supplementis to hire a laboratory technician to assist with the genotyping of samples from bladder cancer cases and controls in order to accelerate the scientific pace and enhance the scope of a f
GENETIC SUSCEPTIBILITY TO CANCERS IF THE PROSTATE AND URINARY BLADDER
This program will prepare Amy M. Pastva, PT, PhD, CCS, for a career as an independent clinician-scientist in academic research medicine, specializing in the study of allergic lung disease. Dr. Pastva has been pursuing rigorous training in cell
THE IN VIVO ROLE OF SURFACTANT PROTEIN A IN ALLERGIC LUNG DISEASE
This project is to examine the biological function of the N-terminus of the IkappaBalpha protein.  We have generated expression constructs of normal IkappaBalpha and IkappaBalphaW11X, which lacks the N-terminal 12 amino acids of IkappaBalpha.
A novel mutation in human IKBlpha identifies a domain essential for function
Relevance to NIAID mission: This application describes a 5-year training program for the development of an academic career in Pediatric Infectious Diseases, with a goal of independently directing research into parasite biology, pathogenesis, an
TARGETING ISOPRENOID BIOSYNTHESIS IN PLASMODIUM FALCIPARUM
The PI is investigating the role of Notch1 and Trib-2 proteins in macrophage fusion and granuloma formation. Three novel Notch-modified transgenic animals were generated by the Principal Investigator, and a Trib2 knock-out animal was recently g
SIGNIFICANCE OF NOTCH1 AND TRIBBLES-2 IN MACROPHAGE FUSION AND GRANULOMA FORMATIO
This proposal describes a two-year Administrative Supplement to my five-year mentor training program to develop an independent clinician-scientist for a career in academic medicine and gene therapy.  The application will further advance my rese
Gene targeting with AAV vectors for the treatment of Osteogenesis Imperfecta
This is an application for an Administrative Supplement (NOT-OD-09-056) for my funded proposal “TRAIL Mediated Apoptosis in Renal Cell Carcinoma” (K08 CA113452). The parent grant hypothesized that the type I interferon, IFNa, could modulate
TRAIL Mediated Apoptosis in Renal Cell Carcinoma
This supplement provides support to retain a project technician.  This work has far reaching implications in the physiology and pathophysiology of skeletal tissues. Alterations in chondrocyte maturation and hypertrophy have catastrophic physiol
The success of TNF blockade for the treatment of Crohn's disease (CD) has lead to the systematic study of other biological therapies. Unfortunately, the usefulness of these newer therapies (e.g. IL-10, IL-11 blockade) has been limited. Therefor
Lymphocyte Trafficking by Chemokines/Adhesion Molecules in Crohn's Disease
Based on my K08 hypothesis that selective combinations of adhesion molecule expression identifies subsets of T cells that preferentially home to the colon and results from the K08 aims, we identified not one but two candidate chemokine receptor
LYMPHOCYTE HOMING MECHANISMS IN NORMAL & INFLAMEDCOLON
This ARRA project is being implemented in order for the FWS and TNC to work together for the purpose of implementing prescribed burns on private lands targeting Native Ecosystems in the State of Texas. With the participation of interested lando
Restore Native Ecosystems' Function to benefit Federal T&E, Neotropical Migrants and Improve Water Quality
Implementing prescribed fire on private lands to restore native ecosystems and landscapes to their historical biological diversity and productivity and decrease wildfire potential.  OCC will work with 3 local conservation districts to provide f
CORONADO RESOURCE CONSERVATION & DEVELOPMENT AREA
Funding for staffing and supplies for Invasive Weed Control in Cochise County, AZ
Invasive Species Control on Desert Grasslands and Cienegas
COASTAL BEND BAYS & ESTUARIES PROGRAM, INC
The purpose is to provide financial and technical assistance for the design and implementation of the Nueces Bay Portland-Causeway Marsh Restoration Project near Indian Point in Nueces Bay, in Nueces County, Texas.   The objectives are to resto
The award funded services to the Sequoyah National Wildlife Refuge from the Student Conservation Association's Conservation Intern (CI) program, which recruits and places qualified young people for environmental and conservation service project
Hunting Program/Visitor Service Program - Sequoyah National Wildlife Refuge
The award funds services to the KOFA National Wildlife Refuge from the Student Conservation Association's Conservation Intern (CI) program, which recruits and places qualified young people for environmental and conservation service projects. An
Habitat Management Intern - KOFA National Wildlife Intern
Geometric Improvements at MD 63 (lower vertical crest)
CR-811/DIXIE HWY FROM SR-810 TO BROWARD/PALM BCH C/L
SR 35 (BASELINE RD) FROM MARICAMP RD (SR 464) TO SR 40 (SILVER SPRINGS)
The two Ho-Chunk Nation Tribal clinics will be purchasing digital x-ray equipment to interface with the electronic health records.                                          The House of Wellness will be purchasing new dental operatory equipment
Signal Reconstruction MD 410 to Wayne Avenue
I-5/196th St SW Interchange Bridge/Ped Improvements
Freeway Performance Initiative - Phase 1 - Interstate 280 Nouthbound in Santa Clara County
Freeway Performance Initiative - Phase 1 - Interstate 280 Southbound in Santa Clara County
Federal Work-study provides need-based financial aid to students.
MISSISSIPPI RIVER CORRIDOR - TENNESSEE, INC.
Mississippi River Corridor - Tennessee was awarded a Clean Diesel Emerging Technology Program Grant to fund a retrofit project targeting marine vessels operating along the Mississippi River.  The general purpose of the grant is to reduce diesel
ARRA ET - MRCT XtrmCat Diesel Kit-Marine Engines
HARC was awarded a National Clean Diesel Funding Assistance Program Grant to fund a retrofit project targeting onroad and offroad vehicles in Texas. The purpose of the grant is to reduce diesel emissions and improve air quality.
THE MISSOURI DEPARTMENT OF NATURAL RESOURCES WAS AWARDED A NATIONAL CLEAN DIESEL FUNDING ASSISTANCE PROGRAM GRANT BY THE ENVIROMENTAL PROTECTION AGENCY TO FUND A RETROFIT AND REPLACEMENT PROJECT TARGETING DIESEL VEHICLES IN THE SAINT LOUIS AND
AMERICAN RECOVERY AND REINVESTMENT NATIONAL CLEAN DIESEL FUNDING FOR MISSOURI
Sioux Falls School District was awarded a National Clean Diesel Funding Assistance Program Grant to fund a replacement project targeting school buses in South Dakota.  The general purpose of the grant is to reduce diesel emissions and improve a
ARRA 2009 supplemental funding of $1,800,000 in hazardous substance funding for RLF grant.
COMMERCE, WASHINGTON STATE DEPARTMENT OF
Environmental remediation of contaminated sites as one step in the process to facilitate redevelopment of the property.
Washington State Dept. of Commerce BF ARRA
Legislative Building 416 Sid Snyder Avenue S.W.
BROWNFIELDS PHASE 1 AND PHASE 2 ASSESSMENTS FOR PETROLEUM AND HAZARDOUS TOXIC SUBSTANCES.
The Environmental Protection Agency (EPA) has awarded the City of Concord with its third Brownfield Assessment Grant.  A brownfiled property is real property, the expansion, redevelopment, or reuse of which may be complicated by the presence or
Brownfields Assessment & Cleanup Cooperative Agreements
Funds to the City of Valdosta, Georgia to be used to conduct community-wide assessments at potential Brownfield sites contaminated with petroleum and hazardous substances.  The City will conduct site prioritization and Phase I and Phase II asse
Brownfields Assessment Cooperative Agreement - Hazardous Substances and Petroleum Community-wide Assessment
Performing environmental assessment activities at eligible brownfields properties contaminated with hazardous substances and petroleum located at the targeted community.
Brownfields Assessment & Clean up Cooperative Agreement
Environmental Assessment of Brownfields Properties located within the City of Cocoa's designated Brownfields Area.
Community-wide Environmental Assessment Cooperative Agreement
ARRA Brownfields cleanup grant for Rainier Court Phase III reclaiming contaminated site for production of affordable housing
Rainier Court Phase III Brownfields Grant
Stimulus - Woonsocket Middle School Replacement Project - This award utilized stimulus funding for cleanup and capping of site.
NORTHWEST NEW MEXICO COUNCIL OF GOVERNMENT
To perform environmental assessment activities at eligible Brownfields properties comtaminated with petroleum and/or hazardous substances on behalf of the Northwest New Mexico Brownfields Coalition.
Northwest New Mexico Brownfields Coalition Assessment Program
Performing environmental assessment activities at eligible Brownfields properties contaminated with petroleum located at the targeted community. Deliverables will be assessment reports.
American Recovery and Reinvestment Act Funding, Kansas City East Village Brownfields Cleanup.  This agreement provides American Recovery and Reinvestment Act funds to the City of Kansas City, Missouri for cleanup of hazardous substance contamin
American Recovery and Reinvestment Act Kansas City East Village Brownfields Cleanup
This award provides America Recovery and Reinvestment Act funds to the City of Cherryvale, Kansas to be used to conduct community-wide assessments on potential brownfields sites contaminated with petroleum. The grant recipient will conduct site
American Recovery and Reinvestment Act - Cherryval Brownfields Petroleum Assessment
The goals of the project funded by this cooperative agreement include site specific and non site specific activities to assess properties and determine if further action is needed in order to facilitate property redevelopment.  Site specific ac
Brownfields Revolving Loan Fund Program provides funding to clean-up hazardous substances & petroleum on contaminated properties.
Brownfields Revolving Loan Fund Program for the City of Aurora, CO
The project will provide funding to rehabilitate the Umatac-Merizo wastewater treatment plant pond and upgrade the aeration system and pump station to eliminate intermittent, unauthorized discharges of partially treated wastewater due to the la
Umatac/Merizo wastewater treatment plant upgrade project   ARRA-Wastewater Treatment Construction Programs
Managed and unmanaged switches, hubs, gateways, routers, wireless networking devices, everything over IP, cables, firmware, memory, interface, adaptors, service packs
NC Department Environment and Natural Resources-Division of Air Quality was awarded a State Clean Diesel Program Grant to fund a retrofit/replacement/repower program targeting school buses, long haul trucks, marine vessels, and other non-road a
ENVIRONMENTAL CONSERVATION, ALASKA DEPARTMENT OF
Alaska Department of Environmental Conservation was awarded a State Clean Diesel Program Grant to fund a retrofit and replacement project or program targeting locomotives and heavy duty diesel vehicles in Alaska.  The general purpose of this gr
ARRA Diesel State Grant Program for Alaska Department of Environmental Conservation
ENVIROMENTAL QUALITY, MISSISSIPPI DEPARTMENT OF
MDEQ was awarded a State Clean Diesel Program Grant to fund a retrofit project or program targeting school buses in Mississippi. The general purpose of this grant is to reduce diesel emissions and improve air quality.
The State of South Carolina was awarded a State Clean Diesel Program Grant to fund retrofit/replacement/repower projects in South Carolina. The general purpose of the grant is to reduce diesel emissions and improve air quality.  This project wi
Virginia Department of Environmental Quality was awarded a State Clean Diesel Grant to fund the following five diesel emission reduction projects.  (1) Diesel retrofit/replacement for up to 155 drayage trucks; (2) State-wide biodiesel buy-down
VA Diesel Emission Reduction Recovery Grant
Grant - This award provides funding under the American Recovery and Reinvestment Act of 2009 to the State of California to capitalize its revolving loan fund for financing the construction of drinking water facilities, green infrastructure, pro
ARRA Capitalization Grants for Drinking Water State Revolving Funds
WATER INFRASTRUCTURE FINANCE AUTHORITY OF ARIZONA
This agreement provides funding under the American Recovery and Reinvestment Act of 2009 to the state of Arizona to capitalize its revolving loan fund for financing the construction of drinking water facilities, green infrastructure, program ad
ENVIRONMENTAL QUALITY, IDAHO DEPARTMENT OF
The award will be used to fund improvements to the State's drinking water distribution and treatment infrastructure.The outcomes will be the maintenance and improvement of drinking water quality and  protection of public health. There will also
Drinking Water State Revolving Fund stimulus grant which provides a source of financing for the construction of water treatment facilities and associated infrastructure, greeen infrastructure, program adminstration and technical assistance acti
Federal Fiscal Year 2009 Stimulus Grant for Fort Stanton and Joint Seals
Cost of living adjustment increase of 1.84% in the amount of $32,378 for Head Start and $11,436 for Early Head Start.  The funds paid for approved costs over the 12 month period following the effective date of the grant to pay for salaries with
The Emergency Food Assistance Program (TEFAP) is a Federal program that helps supplement the diets of low-income Americans, including elderly people, by providing them with emergency food and nutrition assistance at no cost.  Under ARRA TEFAP,
Kansas City Metropolitan ARRA Brownfields Job Training Partnership.  The project will implement a job training program for 92 participants that will lead to     sustainable employment of 69 program participants in the green industry, specifical
KC METROPOLITAN ARRA BROWNFIELDS JOB TRAINING PARTNERSHIP
This application details a three-year renewal of a K01 International Research Scientist Career Development Award focused on identifying human gene polymorphisms related to Vibrio cholerae infection. The program will be conducted under the colla
Identification of human gene polymorphisms related to Vibrio cholerae infection
The America Recovery and Reinvestment Act funds will aid the recipient's efforts to assess and cleanup petroleum leaks from leaking underground storage tanks.
Leaking Underground Storage Tanks (LUST)
To assess and cleanup petroleum releases from leaking underground storage tanks (LUST) sites in Alaska.  The agreement will fund activities such as:  shovel-ready projects, staff management, and oversight activities that will leverage additiona
American Recovery and Reinvestment Act Project
ARRA - Leaking Underground Storage Tank Program This agreement provides ARRA funds as an additional financial assistance source for the recipient's efforts to assess and cleanup petroleum releases from leaking underground storage (LUST) sites i
Funds will be utilized to assess and remediate petroleum contaminated sites throughout the State.  This award was previously reported under award number 2L-95424609-0. The number has been changed at the instruction of EPA.
ARRA Leaking Underground Storage Tank Trust Fund Grant
These funds will assist Tennessee's efforts to assess and cleanup petroleum releases from Leaking Underground Storage Tanks (LUST).  The overall purpose  is to clean up contaminated LUST sites effectively, maximize job creation/retention, and p
NATURAL RESOURCES, GEORGIA DEPARTMENT OF
To assess and cleanup petroleum releases from leaking underground storage tanks (LUST) sites in Georgia.  This agreement will fund shovel-ready projects (sites ready for assesment and cleanup) that are typically orphan or abandonded sites, wher
Leaking Underground Storage Tank Trust Fund  Program
ARRA LEAKING UNDERGROUND STORAGE TANKS TRUST FUND FOR PROVIDING AN ADDTL FUNDING SOURCE FOR EITHER DIRECT SITE WORK OR MGMT-OVERSIGHT ACTIVITIES FOR ORPHAN OR ABANDONED SITES OR  WHERE THERE ARE NO VIABLE TANK OWNERS.
ARRA LEAKING UNDERGROUND STORAGE TANK TRUST FUND
AIR & WASTE MANAGEMENT, DELAWARE DIVISION OF
This award provides an additional financial assistance source for the recipient's efforts to assess and cleanup petroleum releases from leaking underground storage tank (LUST) sites in Delaware. The cooperative agreement will fund several activ
LUST - American Recovery and Reinvestment Act of 2009 (Delaware)
To provide an additional financial assistance source for WVDEP's efforts to assess and cleanup petroleum releases from leaking underground storage tank (LUST) sites in West Virginia. This agreement will fund several activities, such as: shovel-
ENVIRONMENTAL QUALITY, WYOMING DEPARTMENT OF
Leaking Underground Storage Tank (ARRA). Remediate contaminated LUST sites in Wyoming
WY Leaking Underground Storage Tank - ARRA
($157,020) - Bluegrass PRIDE will create a comprehensive electronic green infrastructure manual for elected officials and then use different promotion techniques, to guide decision makers towards making choices for improved water quality.
VT Department of Environmental Conservation will invest in water quality management and green infrastructure (GI) coordination efforts. These activities include but are not limited to admin. of sub-recipient grants awarded and promotion of GI a
Stimulus - Water Quality Management Planning
This ARRA grant supports water quality management planning activities in New Mexico. This is a two (2) year grant for New Mexico’s full allotment of $194,300 appropriated under the American Recovery and Reinvestment Act (ARRA) and authorized
This application describes a comprehensive training program designed to transition Dr. Ryan from a mentored scientist into an independent investigator in the area of Pediatric Gl and Hepatology studying the role of the Notch signaling pathway i
FRINGE GENES AS NOTCH PATHWAY MODIFIERS: ROLE IN BILE DUCT GROWTH AND REMODELING
This is an administrative supplement application for a mentored clinical scientist development award (K08) to conduct genetic and functional studies of the vesicular monoamine transporter 1 (VMAT1 SLC18A1) gene on chromosome 8p21 implicated in
VMAT1 in Bipolar Disorder and Schizophrenia
Hypoxic-ischemic (HI) encephalopathy is a common problem impacting thousands of Americans. Animal models have been created to allow for a greater understanding of the process and determine the efficacy of pharmaceutical agents. One of these is
Neuroprotection in an Animal Model of Neonatal Hypoxia-Ischemia
UNIVERSITY OF NORTH TEXAS HEALTH SCIENCE CENTER AT FORT WORTH
The purpose of this proposed administrative supplement to the K23 parent grant entitled 'Osteopathic Manipulative Medicine in Pregnancy: Physiologic and Clinical Effects,? grant # 1K23AT003304, is to hire one additional full time research coord
Osteopathic Manipulative Medicine in Pregnancy:  Physiologic and Clinical Effects
This project combines 1) in vivo, retrospective assessment of the severity of any post-radiation dental lesions as related to factors such as radiation field parameters, the radiation dose to which teeth were exposed, and the use of salivary gl
Radiation Therapy Impact on Structure/Mechanics of Teeth
This randomized double-blind placebo controlled trial uses a translational research technique (sublingual microcirculatory videomicroscopy during protocol-directed resuscitation), to directly measure microcirculatory blood flow in patients with
Randomized Trial of Inhaled Nitric Oxide to Augment Tissue Perfusion in Sepsis
The purpose of this project is to co-locate a recent master's degree graduate in EHS to perform two essential roles: (1) provide on-site supervision to the EHS caseworkers who are principally responsible providing Problem Solving Therapy (the
Maternal Depression and Early Head Start
The proposed supplement is consistent with the NIMH priority area of “Retaining post-doctoral fellows and early stage investigators in the field of mental health research.”  Funds from this administrative supplement will be used to create a
Psychosocial treatment for pediatric bipolar disorder
The overall goal of the administrative supplement to the parent grant, K23NS060949, “Parkinson’s disease, cognitive impairment, and structural MRI,”  is to investigate the role of white matter microstructural integrity in Parkinson’s di
Parkinson's disease, cognitive impariment, and structural MRI
The focus of my career in patient-oriented research (POR) has been to study how interactions between HIV- 1 and key cells involved in innate and adaptive immunity influence control of HIV-1 replication and disease progression. The ultimate goal
Interface of Innate and Adaptive Immunity in HIV-1 Infection
Funding is sought for a five year mentored training period at Brown University for Dr. Nicola Neretti to transition from physics to independent investigator in computational biology. The candidate has a Physics PhD from Brown University, and ha
COMPUTATIONAL BIOLOGY OF TRANSCRIPTIONAL NETWORKS IN AGING
Asthma is the most common chronic disease of childhood, and it disproportionately affects urban, minority, and disadvantaged children. When implemented correctly, existing evidence-based guidelines from the National Heart, Lung, and Blood Insti
VPP - RT 104, STERLING & VICTORY, CAYUGA
ELEMENTARY AND SECONDARY EDUCATION, MISSOURI DEPARTMENT OF
The Missouri Department of Elementary and Secondary Education received funds through the American Recovery and Reinvestment Act of 2009 (ARRA) to assist in the purchase of equipment for School Food Authorities (SFAs) participating in the Nation
American Recovery and Reinvestment Act of 2009 NSLP Equipment
), by analyzing induced responses to stress during aging, and will generate new mouse models to examine this pathway in the cochlea. Project 3 (Genetic analysis of stress resistance and loss of hearing) focuses on the genetic controls and physi
STRESS PATHWAYS IN AGE-RELATED HEARING LOSS
These studies provide fundamental and basic insights into new pathways through which the immune system responds to organ and tissue transplants. The results of these studies will be useful in the design and implementation of strategies into the
Costimulation and Cytokines in Tolerance
The overall purpose of this award is to fund the conduct of an in-progress research study.  The purpose of the research study is to understand if surgery as a first treatment for Stage IV melanoma will lengthen the survival time compared to non
Surgery, Immunology and Immunotherapy of Human Cancer
Novel Gene Networks in Breast Development and Cancer
This grant proposal focuses our sustained laboratory and clinical research experience in animal and human stem cell biology and leukemia to extend exciting new investigations on normal tissue-specific and cancer stem cells. The investigators in
HEMATOPOIETIC STEM CELLS FOR TRANSPLANTATION
Diabetic gastroparesis is a serious and debilitating complication of diabetes. In the parent grant to this application, we have tested the central hypothesis that interstitial cells of Cajal (ICC) and neuronal nitric oxide synthase (nNOS) are l
(Project Leader: Daniel G. Tenen, Beth Israel Deaconess Medical Center, Harvard Medical School). The administrative core will be responsible for many interactive functions of the program, including regular meetings, seminars, and communication
MITOCHONDRIAL GENETIC DETERMINANTS OF HUMAN PARTURITION AND PRETERM BIRTH  The processes underlying human parturition and etiology of preterm birth are not well-understood. There has been an intense focus in recent years on studies of the compl
Gene-Environmental Interactions in Human Parturition (Recovery Act Administrative Supplement)
There are two scientific goals of this administrative supplement: 1) genotype 3441 copy-number polymorphisms (CNPs) among all 2060 DNA samples from the 1000 Genomes Project using array comparative genomic hybridization or arrayCGH and 2) experi
The long-term goal of our research program continues to be the understanding of the neurobiological basis for motor control. More specifically, we aim at characterizing physiological properties of neurons and neuronal circuits that we consider
Neurobiology of Cerebellar - Brainstem Systems
Animal behavior is both stable and plastic. To these ends, molecules and neural circuits respond to environmental changes, both short-term and long-term pertubations. In some cases, the responses maintain a fixed behavior despite a radically al
Molecular Genetics of Behavioral and Neuronal Function
will be judged by us and the best team will be rewarded.  However, there will be no mandatory participation in the follow-up research, and the individual results of each student will be judged only after sufficient time to complete their resea
Administrative Supplement: Increasing Minority Representation in Radiation Oncology Physics
We originally proposed an 14 month, milestone-driven, benchmarked research plan that extends a parent P20 Center grant focusing on bio-therapeutics development. The research was proposed to be executed by 6 newly hired academic research and tec
A COMBINATORIAL APPROACH TO WOUND HEALING FOR PROTEIN, GENE AND CELL THERAPEUTICS
This proposed project targeting Hispanic migrant workers in South Florida, is a 2-year CBPR-based research education program with the goal of building the knowledge and skills needed at the community level to develop and sustain an effective CB
Center for Substance Use and AIDS Research on Latinos in the United States
Substance Abuse Dependency, Prevention & Treatment
The purpose of this grant is to provide undergraduate students and high school and small college teachers with a research experience working with our COBRE investigators during the summers of 2009 and 2010.  The research to be carried out by
Center for Protein Structure and Function
General purpose of the award was to create education and research experience opportunities in the general area of developmentally-based cardiovascular disease for: 1) undergraduate college students; and, 2) Secondary school science educators
SC COBRE for Developmentally Based Cardiovascular Diseases: Administrative Supplement to Provide Summer Research Experiences for Students and Science Educators.
The proposal is to underwrite the expansion of a nascent core facility (DartMouseTM) recently initiated with Dartmouth COBRE seed funds. DartMouse supports the development of 'speed' congenic mice for COBRE investigators at Dartmouth. In pre-cl
Center for Molecular, Cellular, and Translational Immunological Research
SC IDEA NETWORK OF BIOMEDICAL RESEARCH EXCELLENCE Consistent with the original SC INBRE design, the proposed biomedical research activities will be conducted by collaborative teams. The aims of this supplement are to obtain preliminary data to
SC IDEA NETWORK OF BIOMEDICAL RESEARCH EXCELLENCE
DESCRIPTION (provided by applicant): The North Dakota INBRE has succeeded beyond all reasonable expectations in fulfilling the IDeA program's goal of establishing an undergraduate research culture in the state's primarily undergraduate institu
NORTH DAKOTA INBRE: HEALTH AND THE ENVIRONMENT
West Virginia is a State that has had a historically low success rate in obtaining grant awards from the National Institutes of Health and has been designated as an IDeA State. Marshall University (MU), in partnership with West Virginia Univers
West Virginia IDeA Netwok of Biomedical Research Excellence (WV-INBRE)
The overarching goal of the New Mexico Idea Network of Biomedical Research Excellence (NM-INBRE) is to strengthen biomedical research in New Mexico’s institutions of higher education and to prepare faculty and students for participation in th
Vision loss caused by macular degeneration (AMD) is the leading cause of blindness in developed countries.  This disease involves loss of RPE, death of photoreceptors, and subretinal neovascularization.  Similar pathological manifestations have
This administrative supplement request addresses the 'Advance Translational (T1 & T2) Research' solicitation of the NCRR within the ARRA program. The project proposed for support under an administrative supplement for the CSSO/SD will implement
Center for Biologic Basis of Oral/Systemic Diseases (CB*
The goal of the parent grant is to establish a Center for Visual and Cognitive Neuroscience at North Dakota State University. Emerging from the Center projects is a translational and collaborative project that aims to determine whether training
The purpose of this award is for the renovation of existing satellite laboratory space to accommodate a new in vitro BSL3 facility as part of the overall mission of our COBRE program.  The original mission of our COBRE program was the study of
Vermont Immunology / Infectious Diseases Center
The goals of the supplement are (1) to accelerate the development of a data access system at the NBER that allows simultaneous use of various country surveys on health and aging that are being conducted around the world, and (2) to enhance
NBER Center for Aging and Health Research-Comparative Health Measures
The University of Washington Nathan Shock Center of Excellence in the Basic Biology of Aging provides infrastructure and resource support to the large number of NIA-funded investigators at the University of Washington and affiliated Seattle ins
Nathan Shock Center of Excellence in Basic Biology of Aging
The proposed project will quantify methods to educate Black elders and their families about clinical research and brain donation program participation to develop and implement an educational protocol to increase research participation and donat
Boston University Alzheimer's Disease Core Center
This grant provided research experiences for five (5) undergraduate students in health-related scientific research.  The overall goal of this supplement was to provide enriching scientific experiences for local undergraduate students.  Given th
LIFESPAN/TUFTS/BROWN CENTER FOR AIDS RESEARCH (CFAR)
This project is to participate in the planning activities associated with the project entitled ADOPTion of New Technologies for Remote Data Capture and Protocol Authoring (ADOPT) by providing appropriate clinical and informatics expertise in sc
COMPREHENSIVE CANCER CENTER CORE SUPPORT GRANT
DESCRIPTION (provided by applicant): This is an application for renewed CCSG funding for year 35 of the Albert Einstein Cancer Center which received its first NCI designation in 1972. There are seven established programs. These include: Immunoo
We have, according to the requirements of the ADOPT supplement, participated in all meetings and conference calls to date.  No meetings were scheduled, but two conference calls were scheduled.  We attended the first conference call, and the sec
Cancer Center Support Grant - ADOPT Supplement. Adoption of New Technologies for Remote Data Capture & Protocol Authoring
The purpose of this supplement is to strengthen two core facilities by adding two key pieces of equipment that will improve our capability to support translational research in the area of Cancer Immunology. The Human Immunologic Monitoring (HIM
The NYU Cancer Institute is committed to increasing the number of minority researchers working in cancer related areas. In section 10.7 of our P30 application we identify current programs which focus on efforts to increase the number of researc
This award is to assist with a project to adopt new technologies which is intended to improve the efficiency and effectiveness of the clinical trials process and reduce clinical trial costs, thereby realizing the ultimate goal of more rapid pro
Case Comprehensive Cancer Center Support Grant
UPCI plans to further develop the Clinical Disease Site Programs. To develop translational research of these programs, UPCI intends to recruit new translationally-oriented physician-scientist faculty members and support their career development
Cancer represents a complex set of diseases originating from normal cells with many genetic and epigenetic defects present prior to any treatment. The infrastructure that the Human Tissue Acquisition and Pathology Shared Resource (HTAP) offers
The OHSU Cancer Institute is a matrix cancer center at Oregon Health & Science University (OHSU) in Portland, Oregon. In 1992, OHSU president Dr. Peter Kohler, committed to developing excellence in fundamental cancer research in this University
The University of Iowa Holden Comprehensive Cancer Center (HCCC), a matrix cancer center at the University of Iowa, is applying for renewal of its Cancer Center Support grant. This is the first competitive renewal application for the HCCC. The
The Research Center for Auditory and Vestibular Studies, a P30 Core Center Grant, was established in 2001 to meet the specialized needs of hearing and balance researchers at Washington University and surrounding St. Louis area institutions.  Th
RESEARCH CENTER FOR AUDITORY AND VESTIBULAR STUDIES
DESCRIPTION, OVERALL (provided by applicant): Recent advances in basic research techniques have led to an explosion of information and interest in the role of gastrointestinal peptides in health and disease. The function of these peptides has b
GASTROINTESTINAL HORMONE RESEARCH CORE CENTER
The overarching goal of the Washington University WU Center for Kidney Disease Research (CKDR) is to support centralized resources, facilities, and expertise shared by investigators at WU in order to delineate fundamental mechanisms of renal di
WASHINGTON UNIVERSITY CENTER FOR KIDNEY DISEASE RESEARCH
This project requests continued support for the National Institute of Environmental Health Sciences (NIEHS) Center at the University of Texas Medical Branch (UTMB). The mission of this Center is to integrate, coordinate and foster interactions
CELLULAR RESPONSE MECHANISMS TO ENVIRONMENTAL CHALLENGE
Expansion of the Zebrafish International Resource Center (ZIRC) Cryopreservation Program  Zebrafish is a premiere organism to study vertebrate development, physiology, behavior, genetics, and disease.  Powerful techniques allow efficient genera
The UCSC Genome Browser (genome.ucsc.edu) is a vital resource for the biomedical community, providing timely, convenient access to sequence and annotations for the human and all other vertebrate reference species genomes, along with selected mo
UCSC Center for Genomic Science and the Minority Outreach Program
Genetic variation forms the basis of evolution and human diversity. Data from the Human Genome Project originally suggested that any two humans are 99.9% identical in their DNA sequences. The genetic variation that exists between individuals is
Copy Number Variation in the Human Genome
This request responds to Notice Number (NOT-OD-09-058) / Notice Title (NIH Announces the Availability of Recovery Act Funds for Competitive Revision Applications). It is a competitive revision to P41 LM005799. BioMagResBank (BMRB) is the unique
ARRA Biological Magnetic Resonance Databank: Metabolomics / Small Molecule Activities
Implementation of a web-based version of S.A.G.E. (Statisitcal Analysis for Genetic Epidemiology), preparation of a version of the S.A.G.E. short course suitable for clinical scientists to be given locally, development of a program to detect ge
The overall goal of this research is to study alterations in the brain in neurodegenerative diseases, such as Alzheimer's and Parkinson's disease with magnetic resonance imaging (MRI). The proposals in this research amendment all aim at develop
Resource for MRI of Neurodegenerative Disorders
This award is a supplemental grant to the Center of Research Translation (PI: Kevin Cooper), to enable the conduct of FDA-required animal/pre-clinical toxicologic studies on the investigational drug silicon phthalocyanine Pc 4. One of the goals
NIAMS: oprt (Psoriasis Center of Research Translation)
We propose to provide research experiences for up to 3 undergraduate students and one high school student for the summer of 2009, with the request to repeat this in summer of 2010. We believe that molecular imaging in cancer is a multi-faceted,
The Role of Claustrium in Substance Abuse and Cognition
Funds were requested to accelerate research in the Projects of the Monell-Jefferson Chemosensory Clinical Research Center (CCRC) through the retention and hiring of highly skilled individuals and the continuation and expansion of patient recrui
To meet the goals of the American Recovery Act, and also accelerate discovery for our research goals, we aim to hire 2 new additional research assistants and a new postdoctoral fellow, with partial support of yet another fellow. We also request
Fibrotic Sequelae of Childhood Renal Disease
The Kansas Interdisciplinary Center for PKD Research (Kansas PKD Center) was established to provide support for highly meritorious new research programs to explore the basic mechanisms causing polycystic kidney disease (PKD); to provide oppor
Kansas Interdisciplinary Center for PKD Research
This project exposed an undergraduate student to basic science research. The student wored under the direct supervision of a senior Research Associate in the Department. He carried out a project comparing available antibodies to the four rodent
Molecular Determinants of Pulmonary Arte
DESCRIPTION (provided by applicant): The Specialized Program of Translational Research in Acute Stroke (SPOTRIAS) at the University of California San Diego (UCSD) Stroke Center currently applies the resources of 4 Cores to conduct 3 interrelate
THERAPEUTIC WINDOW FOR ACUTE STROKE THERAPY (P50)
The specific aims of this administrative supplement to the Neuroprotection with Statin Therapy for Acute Recovery Trial (NeuSTART) are to put the procedures in place to expand our Phase 2 study of lovastatin at doses of 640 mg daily in acute is
New York Columbia Collaborative SPOTRIAS
Nonhuman primate (NHP) models area essential to the conduct of translational research and the advancement of biomedical science. There is a critical need to increase the NHP housing and research capacity to address major human health threats. T
SUPPORT FOR NATIONAL PRIMATE RESEARCH CENTER
The focus of the present proposal is related directly to the component of our P51 parent grant intended to enhance research studies applicable to the solution of human health problems, i.e., translational research. Specifically, we are requesti
The Division of Functional Genomics and Infectious Disease at the Washington National Primate Research Center (WaNPRC) is focused on developing high-throughput genomic and proteomic technologies, sophisticated immunologic resources, and advance
WaNPRC P51 ARRA Supplement Genomics Translational
Electronic record systems are becoming the standard for healthcare organizations. The benefits of an EHR system are far-reaching, including improvements in animal care, cost-savings and increased efficiency. Creating the infrastructure to store
ARRA WNPRC Center Support Administrative Supplement ~ Database Development
This is a National Center for Research Resources (NCRR) Base Grant Administrative Supplement to Advance Translational (T1 & T2) Research by supporting enhancement and integration of the nonhuman primate databases at the Southwest National Prima
The Southwest National Primate Research Center: Administrative Supplement to Advance Translational (T1 & T2) Research by supporting enhancement and integration of the nonhuman primate databases at the Southwest National Primate Research Center
Water Quality Management Planning - American Recovery and Reinvestment Act of 2009.  This agreement supports water quality management planning activities authorized under the Clean Water Act and the American Recovery and Reinvestment Act of 200
Water Quality Management Planning-American Recovery and Reinvestment Act of 2009
ENVIRONMENTAL CONSERVATION, NEW YORK DEPARTMENT OF
ARRA grant No. 97234709 supports New York State Department of Environmental Conservation (DEC) water quality management planning activities authorized under the Clean Water Act and the American Recovery and Reinvestment Act (ARRA) of 2009. The
The ARRA Statewide Water Quality Management Plan (SWQMP) is envisioned to address three broad goals.  First the SWQMP would identify, and incorporate existing planning efforts by other programs within the Water Quality Control Division (WQCD) a
Water Quality Management Planning Activites
Colorado Dept of Public Health and Environment
This Cooperative Agreement will provide support for Senior Environmental Employment (SEE) Program enrollees to work in Region X offices and to support EPA stimulus activities with the American Recovery and Reinvestment Act of 2009.
Senior Environmental Employment Program for Region X Operations Stimulus Activities
This cooperative agreement will provide support for Senior Environmental Employment (SEE) enrollees to work in Region II offices to support EPA stimulus activities with the American Recovery and Reinvestment Act of 2009.
Senior Environmental Employment Program for the Region II Operations Stimulus Activities
This cooperative agreement will provide support for Senior Environmental Employment (SEE) Program enrollees to work in the Office of Administration and Resource Management, Washington, DC to support EPA stimulus Activities with the American Rec
Senior Environmental Employment Program for Office of Administration and Resource Management Recovery Act
Our overall objective is to understand why the immune system in SLE (lupus) responds abnormally to nuclear autoantigens from cells undergoing physiologically programmed apoptosis, and how this response could be specifically downregulated for ef
Genetic, Viral and Immunologic Studies in New Zealand Mice
Adenoviruses (Ads) are common human viruses that cause mainly respiratory infections, as well as gastrointestinal infections and severe ocular infections. Modified forms of adenovirus have shown great potential for gene delivery and vector-base
Cryo-EM Structural Studies of Adenovirus Cell Entry
4-1BB (CD137), a member of the TNFR superfamily, strongly influences immune cell function in many inflammatory situations. 4-1BB was originally described as a costimulatory molecule and binding to its known ligand, 4-1BBL, a member of the TNF f
The Role of 4-1BB in T Cell and APC Interactions
Although the first successful human gene therapy was performed in XSCID patients, the occurrence of T cell leukemia in five of twenty successfully treated patients three to six years following treatment has shown that gene therapy is not withou
The Alphavirus genus in the Togaviridae family contains a number of significant human and animal pathogens that are widely distributed on all continents, excluding the Antarctic regions. Some of the alphaviruses, e.g., the Venezuelan, eastern a
INTERACTION OF SINDBIS VIRUS WITH CELLULAR PROCESSES
Adenoviruses are small, non-enveloped viruses containing a linear double stranded DNA genome that were first discovered in 1953. The human adenoviruses are associated with a variety of diseases including upper respiratory infections, gastrointe
DESCRIPTION (provided by applicant): Recognition of pathogens by the innate immune system activates TLR-mediated pathways, resulting in NF-kB induced transcription of inflammatory cytokines. These molecules subsequently direct the initiation of
HYPER-RESPONSIVESNESS TO TLR AGONISTS IN WILD DERIVED MICE
Reaching for objects is a natural and common behavior. A great deal of behavioral and physiological effort has been devoted to understanding reaching behavior. This project is the continuation of a unique attempt to understand how humans are ab
Interaction torques in voluntary turning and reaching
Our long-term goal is to understand the role of the basonuclin gene in skin and hair follicle biology. Basonuclin (BNC1) is a zinc finger protein found in abundance in the keratinocytes of the epidermis and hair follicle. We believe that it coo
A STUDY OF BIOLOGICAL FUNCTION OF BASONUCLIN
The primary goal of the research proposed in this competitive renewal application is to understand the role of Akt downstream signaling pathways in epithelial carcinogenesis. During the previous funding period, we discovered that Akt activation
AKT SIGNALING PATHWAYS IN EPITHELIAL CARCINOGENESIS
The long-range goal of this research is to understand the mechanism of glucocorticosteroid action in lymphoid malignancy, providing information to guide development of novel therapeutic approaches. Glucocorticoids including prednisone and dexam
Mechanism of Steroid Action in Lymphoid Malignancy
The long-term objectives of this proposal are to develop and refine methods of breast cancer staging in patients that are substantially less morbid than current methods, yet still provide the same diagnostic and therapeutic benefits. This proje
Sentinal Node Versus Axillary Dissection in Breast Cancer
We use state-of-the-art technology including computational biological simulations on the Blue Gene/L Super Computer, knockout mouse model and other molecular biological methods for the studies. These preclinical studies are designed to lead to
Study on Ultraviolet Signal Transduction
Signals mediated by tyrosine phosphorylation control a host of important biological activities, and when dysregulated can cause human diseases such as cancer and immune disorders. SH2/SH3 adaptors play a central role in tyrosine kinase signalin
FUNCTIONAL ROLE OF NCK AND CRK BINDING INTERACTIONS
Redox Regulation of Rho-GTPases in the Vasculature - ARRA Rho-like GTPases are important players in vascular function due to their ability to regulate the actin cytoskeleton.  They are involved in physiological processes such as smooth muscle c
Redox Regulation of the rho-GTPases in the vasculature - ARRA
Kaposi's sarcoma, the most prevalent malignancy in AIDS patients, is characterized by proliferating spindle cells of endothelial cell (EC) origin, infiltration by inflammatory cells and the presence of the KS herpesvirus (KSHV) in lesions. The
Tumors appear to be very sensitive to virus infection compared to normal cells.  We aim to exploit these observations by developing novel, viral-based therapies that specifically kill tumor cells. Such strategies should lead to new anti-cancer
In the past funding period we confirmed our major hypothesis that progastrin peptides (PG) exert proliferative/anti-apoptotic/co-carcinogenic effects on intestinal/colonic epithelial cell lines, in vitro and in vivo, and increase the risk of co
ROLE OF ANNEXIN-II IN GROWTH FACTOR/CO-CARCINOGENIC EFFECTSOF PROGASTRIN
Chronic lymphocytic leukemia (CLL) is the most common adult leukemia in the United States and Europe. Recent progress in our understanding of CLL biology and the development of new therapy such as fludarabine-based regimens has led to improveme
NOVEL ROLES OF P53 & ROS IN THERAPY OF REFRACTORY CLL
Nephrogenic Systemic Fibrosis (NSF) is a disabling dermatologic adverse drug reaction associated with Gadolinium Containing Chelating Agents (GCCAs). Dermatologic adverse drug reactions (dADRs) are important and poorly characterized causes of m
Research for Adverse Drug-Events and Reports
Similar to dopamine, glutamate regulation of the reward circuitry involves inputs to the ventral tegmental area and the nucleus accumbens. Functional dysregulation of the circuits has been proposed as neural substrates of drug dependence. Since
Design and Development of Pharmacotherapies for Treating Stimulant Abuse
Serotonin is a neurotransmitter in the brain that plays an important role in complex behaviors including addiction.  We have previously shown that 5 HT1B receptors alter the function of brain reward mechanisms that play a central role in addict
THE ROLE OF 5-HT1B RECEPTORS IN BRAIN REWARD CIRCUITS
For an individual, chronic tobacco use is associated with a significant increase in heart disease and many forms of cancer; the health of non-tobacco users is negatively affected by second- hand smoke. The potential benefits that would come fro
Acquired appetitive properties of nicotine
In that mucosal T lymphocytes are enmeshed in the complex and highly organized network of proteins, glycoproteins, and proteoglycans known as the extracellular matrix (ECM), we propose that the chronicity, exacerbation, and recurrence of IBD ar
Extracellular Matrix in Inflammatory Bowel Disease
Obesity and Type 2 diabetes occurs with an alarming incidence in the United States, altogether affecting more than 120 million people, many of which are children. Currently, more people are obese and have diabetes in the world as compared to th
REGULATION OF HYPOTHALAMIC POMC BY LEPTIN
The proposed research is focused on the development of high frequency dynamic nuclear polarization (DNP) nuclear magnetic resonance (NMR) as an approach to enhance sensitivity in solid state and solution NMR based structural biology experiments
The specific aims are: 1) To establish the mechanism(s) of insulin activation of Akt on CYP2E1 gene transcription; 2) To examine the mechanism(s) by which insulin activation of mTOR regulates CYP2E1 mRNA translation and miRNA translation repres
NITROGEN HETEROCYCLES: METALBOLIC EFFECTS AND TOXICITY
The long-term objective is to determine the impact of environmental toxicants on the peripheral and central olfactory tissues, and the role of xenobiotic exposure in the etiology of anosmia and other diseases concerning the nasal cavity. Our fo
OLFACTORY TOXICITY OF ENVIRONMENTAL AGENTS
Statistical Methods for Population Health Research on Chemical Mixtures. PI has moved to Harvard; grant to be transferred to Harvard.
Statistical Methods for Population Healt
Though current computational models of visual processing provide a good account of processing of simple images such as lines and gratings, our understanding of the processing of natural scenes is substantially incomplete. Several lines of reaso
Central Processing of Visual Information
The long-term objectives of this proposal are to fully define the molecular genetics of human color vision and its common defects, and to elucidate the mechanisms of regulation of expression of the X-linked red-green color vision locus. A remar
. Thus, myocilin is not secreted in a traditional manner, but exits trabecular meshwork cells and enters the extracellular compartment associated with exosomes. The overall goal of the present proposal is to determine the function of myocilin i
Molecular Basis of Myocilin Function in the Human Eye
The goal of the proposed research is to understand the roles of centrifugal input in vertebrate retinas. In all vertebrates (include humans), the retinas receive centrifugal input from the brain. In fish, the centrifugal input originates from t
Centrifugal Modulation of Visual Sensitivity
Glaucoma is one of the leading causes of blindness worldwide. Elevated intraocular pressure (IOP) is the primary risk factor for optic nerve damage in glaucoma. Many studies conducted on human subjects and animal models have shown that marijuan
ARRA Cannabinoid Receptors and Novel Antiglaucoma Drugs
The long-term goals are to comprehensively characterize extraocular muscles (EOMs) at the molecular level. Precise functioning of EOMs is an absolute requirement for optimal vision in humans. EOMs are highly specialized and undergo a wide range
MOLECULAR CHARACTERIZATION OF EXTRAOCULAR MUSCLE (EOM)
The major goal of this proposal is to identify biomarkers that could be used as eventual targets for prevention or therapeutic intervention of the development and progression of advanced age-related macular degeneration (AMD) using a phenotypic
ARRA-Sibling Study of Age-Related Macular degeneration
Studies described in this proposal seek to elucidate thrombospondin-1  (TSP-1) mediated immune regulation and associated mechanisms that may prevent ocular inflammaton.  The first aim seeks to determine immunologic mechanisms underlying ocular
Thrombospondin-dependent mechanisms that regulate ocular inflammation.
ARRU - Enzymatic Mechanism of E. coli Helicases  DNA helicases provide the primary mechanism by which duplex DNA is converted to single-stranded DNA (ssDNA) for use as a template in DNA replication and repair or as a substrate in recombination.
ARRU - Enzymatic Mechanism of E. coli Helicases
This proposal focuses on research in the area of acyclic diastereoselective synthesis, with emphasis on the development of novel allylmetal reagents for application to the synthesis of several biologically active natural products, including nig
Acyclic Diastereoselection: Methodology and Synthesis
This project is a continuation of a line of investigation we started more than 20 years ago. We then discovered a protein, called NF-KB, that subsequent work has shown to play a key role in inflammation and immunity. Here we propose four lines
NF-KAPPAB: ORCHESTRATION OF THE INFLAMMATORY RESPONSE
Insulators are elements required for transcriptional fidelity in eukaryotic genomes. Prevailing models suggest that insulators are structural components that divide chromosomes into loop domains to constrain enhancer and silencer action. The go
Regulation of Tissue-Specific Gene Expression
To understand how the microtubule motors, cytoplasmic dynein and kinesins, find and transport cargoes to specific cellular destinations, we need to know much more about how motors are attached to cargoes. The extended morphology of axons and de
STRUCTURE AND FUNCTION OF CYTOPLASMIC DYNEIN
The body’s first line of defense against infection is the circulating white blood cells that detect and respond to tissue damage.  These cells move rapidly towards the site of injury using an amoeboid type of motility.  This movement is chara
Study of Cell Adhesion through an Analysis of Myosin 7
Grant Number 2R01 GM047297 Mechanisms of Phosphoryl Transfer  This project studies several enzymes involved in controlling the levels of phosphorylation of proteins in humans, a factor in many diseases.  Abstract The project will utilize a mult
Proteins play a central role in living organisms, serving, for example, as enzymes that catalyze metabolic reactions, as structural or mechanical units, and as cell signaling molecules. The field of proteomics, which entails large scale identif
INFLUENCE OF PEPTIDE STRUCTURE ON DISSOCIATION
The grant entitled ?How does a4b1 integrin regulate cell migration? proposes to investigate a novel association between the cytoplasmic tail of a4 integrin and non-muscle myosin IIA (MIIA). Two aims are proposed to study this association: (1) c
HOW DOES A4B1 INTEGRIN REGULATE CELL MIGRATION?
DESCRIPTION (provided by applicant): This application is a revised proposal to assess aspects of adrenergic receptor and P2Y purinergic receptor signaling. Our recent, preliminary data for this application include the identification and cloning
ADRENERGIC AND PURINERGIC REGULATION OF TARGET CELLS
Mitochondria play a pivotal role in cell survival and tissue development by virtue of their role in energy metabolism, regulation of cellular Ca2+ homeostasis and apoptosis. Given this multifactorial role, these aspects of cellular function mus
Molecular Structure and Regulation of the Permeability Transition Pore
Natural Killer T (NKT) cells are potent regulatory T cells that have been shown to be intimately involved in the response to infection and tumor progression. There is also strong evidence that NKT cells may regulate the immune system in such a
Harnessing NKT Cell Activation by Glycolipids
The immunological response to placental MHC class I expression is considered to be important, yet neither the mechanisms nor the significance of this response in humans or nonhuman primates is well understood.  We have recently shown that in pr
ARRA Uterine NK Cells in Primate Pregnancy
DESCRIPTION (provided by principal investigator): Preterm birth is a leading cause of infant mortality and morbidity in the U.S. and across the globe. Infection has consistently been identified as an important risk factor for preterm birth. A t
ORAL AND VAGINAL MICROBES, HUMAN GENOTYPE, AND PRETERM BIRTH
Nongenomic Androgen Signaling in Sertoli Cells. The long-term goal of this project remains to determine the molecular and cellular mechanisms by which testosterone regulates spermatogenesis. Aim 1 is to determine whether non-classical signaling
Nongenomic Androgen Signaling in Sertolli Cells
Protein Misfolding and Disease-ARRA  In our ARRA-funded project,  we first aim to quantify the binding affinity of the small GTPase Rac1 to Cu, Zn superoxide dismutase (SOD1) using a FRET-based fluorescence assay and NMR. These studies will als
Defining Residues Critical to Fibrin Clot Structure - ARRA
Neovascularization of injured tissue is fundamental for its regeneration. Recent studies have indicated an intimate relationship between angiogenesis, vasculogenesis and the repair of injured nerves. Our preliminary data indicate that repair of
Therapeutic Angiogenesis in Vascular Medicine III
The actions of the renin-angiotensin system (RAS) to control blood pressure are primarily mediated by type I (AT1) angiotensin receptors. In work done during the previous funding period using a kidney cross- transplantation model, we demonstrat
Angiotensin receptor genes and blood pressure regulation
Myocardial energetics is impaired and fatty acid oxidation decreased in failing hearts of both animal models and patients. Although it is increasingly recognized that altered cardiac energy metabolism is integral of the development and progress
Autophagy is manifested by degradation of cytoplasmic organelles via a lysosomal pathway, involving rearrangement of intracellular membranes to sequester damaged proteins or organelles within formed membrane vesicles, or autophagosomes. Autopha
Heme Oxygenase 1/Carbon Monoxide in Lung Vascular Injury
Notch functions to modulate cell-fate decisions during vascular development. The overall objectives are to define roles for Notch during sprouting of blood vessels and lymphatic specification and remodeling. In the first part, we explore the hy
Notch Function in Vascular Biology and Angiogenesis
This award is entitled “Regulation of Endothelial Cell Function by Sprouty”.  Receptor tyrosine kinase (RTK)-initiated signaling mechanisms are major pathways critical for vascular development and angiogenesis, and mediate signals from angi
Regulation of Endothelial Cell Function by Sprouty
Much research has been directed at understanding the cellular and molecular mechanisms responsible for the steep increase of active force with increasing length in cardiac muscle (the Frank-Starling mechanism).  Our studies have lead us to beli
Length Regulation of Cardiac Contraction
Vascular gas embolism contributes to cerebral dysfunction in over 300,000 cardiopulmonary bypass patients in the US annually. Transient and permanent brain abnormalities occur. These include reduced cognitive function, speech and speech process
ACTIVATION OF CLOTTING %26 CELL ADHESION: GAS EMBOLISM
This project addresses mechanisms that are responsible for formation of the ventricular chamber of the heart during mouse embryonic development. We have advanced a model in which signals secreted from the epicardium promote cell division and mo
Cardiomyocyte Proliferation and Ventricular Morphogenesis
Antiretroviral nucleoside analogs used in highly active antiretroviral therapy (HAART) are associated with a variety of tissue toxicities associated with mitochondrial DNA depletion, suggesting a block in mt-DNA replication. Since the triphosph
Mitochondrial Toxicity of Antiviral Nucleosides
In the previous proposal, the central hypothesis was to determine if CRP promotes atherothrombosis by effects on both endothelial cells and monocytes. We have now executed all four aims of this proposal and have advanced the field with regards
New approaches to implement proven preventive and lifestyle interventions are needed to reach the NHLBI strategic plan goal to speed the translation of science into practice and reduce the public health burden of cardiovascular disease (CVD). T
Family Cardiac Caregiver Investigation to Evaluate Outcomes (FIT-O)
ARRA Titin Splicing Mechanisms and Physical Implications
The sympathetic drive emanating from the brain is increased in animal models of hypertension and in patients with hypertension. The paraventricular nucleus (PVN) of the hypothalamus is an important site for the control of sympathetic outflow th
SYNAPTIC MECHANISMS REGULATING SYMPATHETIC DRIVE
In the prefrontal cortex, a brain area implicated in pathophysiology of schizophrenia, neurons receive numerous synaptic contacts from dopamine-rich fibers. At present, it is not clear how exactly release of  dopamine affects the activity of co
DOPAMINERGIC MODULATION OF DENDRITIC EXCITABILITY
This is a revised, competitive renewal application for the Genetics of Microangiopathic Brain Injury (GMBI) study, initially funded in 2001 as an ancillary study to the Genetic Epidemiology Network of Arteriopathy (GENOA) and Family Blood Press
Genetics of Microangiopathic Brain Injury.
Localization of mRNAs with subsequent translation into new proteins provides a means to geographically regulate neuronal protein composition in distinct subcellular regions. In axons, this localized protein synthesis is needed for growth cone g
MOLECULAR DETERMINANTS OF AXONAL RNA TRANSLATION
The first aim is to relate signaling intermediates in the MAPK pathway to activity-dependent gene induction and changes in synaptic organization in human epileptic neocortex.  The second is to use an eplieptic model in the rat to determine the
ACTIVITY-DEPENDENT GENE EXPRESSION IN HUMAN EPILEPSY
The development of a simple, high-yielding chain extension reaction that facilitates the preparation of heavily functionalized, amino acid-derived ?-keto esters is proposed. The utility of this method is anticipated for the preparation of ketom
Zinc Carbenoid Approach to Peptide Isosteres
The methylotrophic yeast, Pichia pastoris, is a popular protein expression system because of its ability to produce high levels of heterologous gene products either intracellularly or extracellularly. Targetting proteins to the extracellullar m
ANALYSIS OF PROTEIN SECRETION IN PICHIA PASTORIS
This application is in response to NOT-OD-09-060 NIDDK FY2009 Program for Administrative Supplements Utilizing Recovery Act Funds: Summer Research Experiences for Students and Science Educators'. It requests support for three undergraduate stud
This overall research endeavor has the broad goal to develop placement methods for in-situ sediment remediation amendments. The parent grant is In-Situ Sediment Remediation Using Benthic Waterjet Amendment Placement (NIH# 5R01ES016158 ). The su
In-situ Sediment Remediation using benthic Waterjet amendment placement
This proposal is in response to the NIH and NCI announcement on the Availability of Recovery Act Funds for Administrative Supplements (NOT-OD-09-056) for the R00 phase of the Pathway to Independence Award. I believe that the studies will greatl
Role of EGFR mutations and new therapeutics in lung cancer
The androgen receptor (AR), a ligand-dependent transcription factor, plays a key role in the onset and progression of prostate cancer and is a therapeutic target. In K99 phase we have defined the direct ARdependent target genes in both androgen
(ARRA) Genome-wide analysis of transcription factor function in prostate cancer
The purpose of this summer administrative supplement was to give promising students the opportunity to gain hands-on experience in a translational study testing the role of genetics in pharmacological treatment response for alcohol dependence.
A New Pharmacotherapy for Alcohol Dependence: Olanzapine
are more likely to recover, and lengthening time horizons may enhance positive outcomes. The time horizon variable thus may have moderating and mediating effects on recovery attempts. Extended self-monitoring (SM), an intervention suitable for
RECOVERY AND HELP-SEEKING PROCESSES IN PROBLEM DRINKERS
The purpose of this award is to provide funds to support research projects begun under the parent project (AA009986) and to develop new avenues of research on defining how ethanol inhibits glutamate receptor function.  This work utilizes molecu
Ethanol Sensitivity of Native and Cloned NMDA Receptors
Despite significant efforts to educate women to not drink during pregnancy, the incidence of Fetal Alcohol Spectrum Disorders has not declined making it important to obtain understanding of the mechanisms by which prenatal alcohol exposure cau
OVINE MODEL SYSTEM FOR ALCOHOL RELATED BIRTH DEFECTS
Alcoholism and alcohol abuse are complicating factors in most chronic medical and psychiatric illnesses. Alcohol physiological dependence and associated withdrawal episodes are thought to constitute a powerful motivational force that perpetuate
THE ROLE OF MPDZ IN ETHANOL WITHDRAWAL AND GENETICALLY CORRELATED BEHAVIORS
Acute alcoholic hepatitis is a severe disease that has a poor outcome and limited therapeutic approaches. Hepatitis C infection worsens the outcome of alcoholic liver disease and there are limited therapeutic approaches. Ongoing studies have de
Mechanisms of Liver Injury by Hepatitis C and Alcohol
Alcohol is an important teratogen. Much research has focused on the sensitivity of the third- trimester period of brain development, where ethanol has been shown to be neuro-toxic. However, we know very little about the vulnerability of the sec
FETAL ALCOHOL EXPOSURE AND NEURODEVELOPMET
The parent grant for this Administrative Supplement investigates the effects of ethanol on excitation-contraction (E C) coupling, using animal models and isolated cell systems.  Our work to date has shown that both acute and chronic ethanol exp
Ethanol on Excitation-Contraction in Cardiac Cells
DESCRIPTION (provided by applicant): The middle school years are peak years for initiation of alcohol and marijuana (Johnston et al., 2004). Unfortunately, most youth who engage in substance use and experience problems are unlikely to voluntari
BRIEF VOLUNTARY ALCOHOL AND DRUG INTERVENTION FOR MIDDLE SCHOOL YOUTH
animals, we will be able to track any changes that might occur early in alcohol abuse which is something that cannot be accomplished in human studies. Another goal is to adapt imaging tools and computer software that are used to measure the br
Measuring Alcohol and Stress Interactions with Structural and Perfusion MRI
Dopaminergic transmission in the brain’s mesocorticolimbic system is thought to be a significant factor in alcohol abuse and dependence. Most research on the dopaminergic response to alcohol and its conditioned cues is nevertheless done in ro
Habits and cues in alcohol drinking:  Dynamic striatal activity - ARRA  This grant is an administrative supplement in response to NOT-OD-09-060 “NIH Announces the Availability of Recovery Act Funds for Administrative Supplements Providing Sum
Habits and cues in alcohol drinking:  Dynamic striatal activity (ARRA)
Many older adults are less steady when exerting low forces and lifting light loads. The greater fluctuations in force exhibited by older adults can be caused either by increased discharge rate variability or by altered amounts of correlated act
The broad, long-term objectives of this research are to elucidate the mechanisms underlying the increase in insulin sensitivity for glucose metabolism that is a hallmark and major health benefit of calorie restriction (CR; consuming 60% of ad l
AGING, CALORIE RESTRICTION AND INSULIN SIGNALING
Many middle-aged and older adults believe as they age that memory declines are inevitable and there is little that can be done. Such beliefs of low self-efficacy and limited control over memory aging are associated with poorer performance on a
Phosphate homeostasis is maintained primarily by a bone-kidney endocrine axis. When phosphate is in excess, fibroblast growth factor-23 (FGF23) is secreted from bone and acts on kidney to promote phosphate excretion into urine, thereby inducing
Effects of Klotho Protein on Aging and Metabolism - ARRA Stimulus Admin Suppl
This is a request competitive revision of the parent grant R01 AG019787 in response to Notice Number (NOT-OD-09-058): NIH Announces the Availability of Recovery Act Funds for Competitive Revision. The goal of the parent application is to study
Somatic mtDNA mutations in the brain aging: a single-cell approach
This project will use ARRA supplement funds to enhance the research productivity outlined by the funded NIH NIA grant 5R01-AG26553-3 (Robinson) entitled: Phase-Locked Postural Perturbation Psychophysical Models, by involving students and scienc
Phase-Locked Postural Pertubation Pschophsyical Models
This administrative supplement award is linked to the parent grant 1R01 AG030539 entitled “Cerebral amyloidosis and dementia” that proposes the study of alternative models of neurodegeneration in close comparison with Alzheimer’s disease
This application is a request for supplemental funds to support Undergraduate Summer  Research  related to the studies proposed in the parent application R01AG031067 entitled “Redox Control of MMP-1 and Senescence”.  Matrix metalloproteinas
Specific aims of the supplement: Specific Aim 1: To enhance the activities of the CITAD clinical trial by increasing the tempo of participant recruitment by providing $10,000 for two years in direct costs to all study sites. This will result in
CITALOPRAM TREATMENT FOR AGITATION IN ALZHEIMER DEMENTIA
Hot flushes pose a significant public health concern world-wide. These perimenopausal symptoms are the primary reason that women seek medical care during the menopausal transition. Hot flushes often negatively impact the quality of life of wome
Novel Treatment of menopausal hot flushes with an extradiol prodrug
This is an application in response to notice NOT-OD-09-056, requesting a supplement to grant 5R01AG031722-32, which focuses on the role of epigenetic mechanisms in A-beta¿s effects on plasticity and memory formation.  This supplement applicati
TROPHIC INTERACTIONS OF NERVE AND MUSCLE
This revised proposal seeks support for an investigator-initiated research project into the cellular and molecular means used by intermediate hosts of a human parasite to immunologically attack and kill these parasites. The broad, long-term obj
Underlying Mechanisms of Schistosome/Snail Compatibility
The purpose of our research is to explain antigen presentation by class II MHC molecules having a strong biochemical, quantitative and mechanistic foundation in order to avoid the many empiricisms that dominate this complex area. We investigate
Although the brain is an immune privileged site, adaptive immunity can provide resistance to various infectious diseases that affect the CMS. This is illustrated by the important role that T cells play in resistance to Toxoplasmic encephalitis
Alzheimer's Disease (AD) is an age-associated dementia for which there is currently no cure. AD is characterized by memory deficits, loss of CNS neurons, and eventually death. One of the prominent events in AD is the CNS presence of plaques tha
CALCINEURIN INHIBITION FOR REVERSING THE COGNITIVE EFFECTS OF AMYLOID
The major focus of the original grant was on the molecular mechanisms within CD43 that regulates T cell trafficking.  Each aim in the original approved application proposed to define the role of CD43 and interacting molecular partners on T cell
.  The central theme of the proposal is to define the structure and assembly mechanism of the IL-10 receptor complex, which results in IL-10 biological activities.  IL-10  signaling plays a critical role T-cell exhaustion the contributes to imm
STRUCTURE STUDIES ON PROTEINS THAT MODULATE IL-10 ACTION
In 2007, our group was awarded a 5 year continuation(2007-2012)  of ourR01, entiteld ' The role of cellular factors in the HIV-1 capsid assemblypathway'.  Key goals in this R01 were to: Identify novel cellular factorsin the 80S/150S assembly in
The role of cellular factors in the HIV-1 capsid assembly pathway
antigen-presenting cells in expressing lymphocyte costimulatory proteins and activating unsensitized, naive T cells. Third, eosinophils, in contrast to other antigen-presenting cells, contain preformed stores of diverse cytokines that can be r
AIRWAYS EOSINOPHILS AS ANTIGEN-PRESENTING CELLS IN ASTHMA
We will investigate whether IgE levels regulate mast cell numbers in the intestine during a response to food allergens. This work has been completed by Natalia Diaz who was hired under this award as a summer student and has now left the lab.
Regulation of Immune Responses by IgE and Mast Cells
Vibrio cholerae causes the disease cholera and is a natural inhabitant of aquatic environments. Seasonal cholera outbreaks occur where the disease is endemic and can spread worldwide. V. cholerae's ability to cause epidemics is tied to its abil
SMOOTH TO RUGOSE PHASE VARIATION IN VIBRIO CHOLERAE
The rational design of a curative therapy must entail targeting the suppression of pathogenic Th2 cells.  Given that both IFN-a and IFN-B are routinely used to treat hepatitis C and multiple sclerosis, our novel studies will lay the groundwork
Type 1 Interferon-Regulated T Helper Development - ARRA Stimulus Summer Student
DESCRIPTION (provided by applicant):  The lentivirus virion infectivity factor (Vif) is an accessory protein that is required for productive replications of the virus in primary cells and some, but not all, transformed T cell lines.  HIV-1 that
APOBEC3G/CEM15 Inhibition of Lentivirus Replication
The innate immune system provides acute defense against infectious agents and environment toxicants. At the core of this defense system are sensory molecules or receptors that are expressed by most cells of the organism. The existence of these
We are requesting additional funding to maintain productivity on this project. The funding will be used for maintaining the employment of existing members of my laboratory, covering additional costs associated with reagents, biochemicals, mouse
Modulation of T Cell Activation and Tolerance by DRAK2
The parent grant was funded for studies on the effects of TIM-1 ligation on T cell activation. This includes determination of the effects of TIM-1 ligands and specific antibodies on T cell cytokine production and effector development, and detai
Regulation of T Cell Activation and Differentiation by TIM-1
Chlamydia trachomatis has a marked tissue tropism, replicating almost exclusively in epithelial cells lining the reproductive tract. The Chlamydia muridarum mouse model for human C. trachomatis disease has clearly demonstrated that T cells medi
Cellular Immunity to Chlamydia at the Epithelial Interface
The overall purpose of the award is to determine whether pharmacological Inositol (1 ,4,5) Trisphosphate 3-kinase B (ItpkB)-inhibition could provide an avenue towards cost effectively reducing detrimental T cell function and cytokine storm in s
Inositol-Trisphosphate Kinase B (ltpkB) in T Cell Development and Function
Interferon (IFN) and IFN-stimulated gene products (ISGs) are essential components of the innate immune response to viral infection. Conversely, viruses need to limit the induction or function of ISGs for successful infection of their respective
Modulation of Innate Immune Responses by Cytomegalovirus
Purchase of an Axio Observer Z1 Motorized Inverted Research Microscope equipped for live cell imaging and image deconvolution from Carl Zeiss Microimaging of New England.   The overall goal of the parent project is to identify and characterize
Molecular Mechanism of Entamoeba Histolytica Phagoctosis
The aims of the parent project include the development of replication incompetent Moloney Murine Leukemia Virus (MMLV) vectors pseudotyped with vesicular stomatitis virus glycoprotein (VSVG) and investigation of the vectors for transduction of
Transduction of Schistosoma mansoni by pseudotyped retrovirus
Leishmaniasis is a serious disease associated with a wide range of clinical manifestations caused by intracellular protozoan parasites belonging to the Genus Leishmania. While the host immune response is important in the outcome of infection, d
INITIATION OF IMMUNE RESPONSE IN CHRONIC LEISHMANIASIS
Modified Triterpines as Potent HIV Fusion Inhibitors  Prior studies on the natural triterpene betulinic acid (1) led to our discovery and development of Bevirimat (2), a modified triterpene and the first-in-class HIV maturation inhibitor.  In t
Modified Triterpines as Potent HIV Fusion Inhibitors
Chronic Viral infections represent a major health problem and have been associated with deficient CD8 T cells responses. We recently found that attenuation of TGF?Ò signaling during chronic Lymphocytic choriomeningitis virus infection results
INHIBITORY PATHWAYS UNDERLYING VIRAL PERSISTANCE IN VIVO
One of the two central hypotheses of the parent grant (R01 AR27065) was that bone strength estimates by finite element (FE) analyses, which can now be obtained from clinical quantitative computed tomography (QCT) images, will enhance the abilit
Epidemiology of Age-Related bone Loss and Fractures
The goal of this project is to determine the role of actomyosin structural dynamics in the molecular mechanism of force generation in muscle. Emphasis is placed on the use of high-resolution and time- resolved (TR) spectroscopy to test and revi
Molecular Dynamics of Muscle Contraction
This supplement to NIAMS grant R01AR041135 provided funds to identify genetic modifiers of Loeys-Dietz syndrome using mouse models. This funding will support personnel, reagent and service costs.
The long-term objective of our research program is to understand transcriptional control of epidermal development and differentiation within the epidermis. One critical function of the epidermis is to form an effective permeability barrier; def
Transcriptional Co-Regulatiors in Epidermis (Supplement NOT-OD-09-056)
Myotonic dystrophy type 1 [DM1] leads to maldevelopment, myotonia, and wasting of skeletal muscle. DM1 is caused by an unstable CTG repeat expansion in the 3' untranslated region of DMPK. Our central hypothesis is that skeletal muscle findings
PATHOGENESIS OF MYOPATHY IN MODELS OF MYOTONIC DYSTROPHY
The proposed studies address very basic questions about the postnatal growth of phrenic motoneurons and diaphragm muscle (DIAm) fibers. Such growth of phrenic motoneurons and DIAm fibers is necessary to meet the increasing functional diversity
Influence of Innervation on Diaphragm Muscle Growth
mice experienced an exaggerated fatigue response to mild exercise due to deficient sarcolemmal nNOS signaling. Thus, like our rescue mouse, we found that this specific form of fatigue can occur in mouse models that do not have muscle pathology
With the discovery that mutations in fourteen different keratin genes can cause eight distinct epithelial fragility disorders, comes the realization that the keratin filament cytoskeleton is crucial to the structural integrity of epithelial tis
Regulation and Function of Keratins in the Epidermis
We are interested in elucidating the molecular mechanisms involved in tissue stem cell self-renewal and fate choice, in normal tissue development and homeostasis. Stem cells hold great promises for future therapies of numerous deadly diseases,
SLOWLY CYCLING CELLS AND HAIR FOLLICLE STEM CELLS
The goal of this proposed administrative supplement grant is to determine risk factors for tumor recurrence after treatment of nonmelanoma skin cancer (NMSC). In particular, data from the NIMSC Cohort Study (funded by the parent grant) will be
Long-Term Outcomes of Nonmelanoma Skin Cancer
In the skeletally mature individual, hyaline articular cartilage does not heal effectively when injured and the natural progression of acquired articular cartilage defects is predictably poor, commonly culminating in joint arthrosis. Physician
IN VIVO PERFORMANCE OF OSTEOCHONDRAL ALLOGRAFTS
Paget's disease (PD) is the second most common bone disease and affects 1-2 million patients in the U.S. This competitive revision will test the hypothesis that both an environmental factor [measles virus nucleocapsid protein (MVNP)] and a gene
MVNP, p62P392L and IL-6 in the Pathogenesis of PD
This project seeks to expand the scope of a project that is directed at understanding the role of nuclear Abl tyrosine kinase in DNA damage-induced cell death response. DNA damage inducers, i.e., genotoxins, are some of the most effective agent
NUCLEAR FUNCTION OF ABL IN DNA DAMAGE RESPONSE
EGF receptor (EGFR) ligands are produced as type 1 transmembrane proteins that are cleaved from the cell surface to produce soluble ligand. EGFR activation can be achieved by soluble ligand (autocrine or paracrine) or by membrane-tethered ligan
NF-?B transcription factors play a key role in the proliferation and survival of many human cancers, especially ones of B-lymphoid cell origin such as Hodgkin’s lymphoma and diffuse large B-cell lymphoma (DLBCL). The primary goal of the paren
Transformation of Cells by the REL Oncogene
The goals of this supplement are to increase our productivity and reduce environmental waste. This application is a request for an administrative supplement from the American Recovery and Reinvestment Act of 2009 for our parent grant, CA60651,
MOUSE MODELS TO STUDY GONADAL TUMOR DEVELOPMENT - PARENT GRANT TITLE CA060651
The goal of this supplement is to accelerate the work originally proposed as part of Specific Aim 3 of the award entitled “p63 Signaling in Epithelial Cell Growth and Cancer”, which focuses on analysis of ?Np63?-associated proteins to ident
P63 Signaling and Cellular Response After Stress
The goal of this project is to carry out a set of definitive experiments on key novel concepts emanating from the original application currently under a non-cost extension and at the same time consolidating the team presently working in the pro
BIOLOGY OF KSHV/HHV8 G PROTEIN COUPLED RECEPTOR
Retroviruses interact intimately with their hosts, usurping cellular pathways to complete their life cycles. Identification of novel host factors that contribute to virus replication will enhance our understanding of retrovirus-cell interaction
NUCLEAR TRAFFICKING OF THE RETROVIRAL GAG PROTEIN
We learned that the tobacco prevention intervention that we developed and experimentally evaluated in 48 Oregon high schools made a significant impact on adolescent smoking, alcohol and marijuana use, and depression. At the same time, we have
Randomized Trial of a State Tobacco Prevention Program -- ARRA Administrative Supplement
The purpose of this research is to identify a novel signaling pathway down stream of epithelial basolateral junctions that suppresses invasion and metastasis.
This administrative supplement request is (1) for funds to purchase a new bench top flow cytometric analyzer with the ability to detect seven colors of fluorescence from three lasers, and (2) to take advantage of a greatly superior technical a
LINEAGE COMMITMENT MECHANISMS IN LYMPHOID PRECURSORS
Acute lymphoblastic leukemia (ALL) is the most common childhood malignancy, with a five-year survival rate approaching 80%. We have shown highly significant differences in survival among ethnic and racial groups. The remission rates were compar
ETHNIC DIFFERENCES IN SURVIVAL AFTER CHILDHOOD ALL
Bleeding and thrombotic disorders are characterized by significant phenotypic variability. Over the last decade important advances have been made in the understanding of the molecular basis of these disorders; however a large portion of the obs
Use of microfluidics in determining hemostatic phenotypes
This application addresses the Challenge Area 06 of 'Enabling Technologies and Prevention' and the specific Challenge Topic 06-HL-104 of 'enabling technologies involving the development of nanotools for pulmonary medicine, particularly aimed at
Zipcode based nano-imaging of hypertensive pulmonary arteries
This application addresses Challenge Topic 03-HL-101* to identify and validate clinically relevant, quantifiable biomarkers of diagnostic and therapeutic responses for blood and vascular dysfunction - specifically, the antiphospholipid syndrome
NOVEL BIOMARKERS FOR MECHANISTIC DIAGNOSIS OF THE ANTIPHOSPHOLIPID SYNDROME
Atrial fibrillation (AF) is the most common sustained arrhythmia in clinical practice, affecting more than 2 million individuals in the US, with growing prevalence as the population ages. Moreover, AF is associated with a higher incidence of st
Risk Prediction of Atrial Fibrilation: Clinical, Biological, and Genetic Markers
DESCRIPTION (provided by applicant): This application addresses the broad Challenge Area (03) Biomarker Discovery and Validation and the specific Challenge Topic, 03-HL-101: Identify and validate clinically relevant, quantifiable biomarkers of
GRAFT VERSUS HOST DISEASE BIOMARKERS: PREDICTION OF ONSET AND RESPONSE TO THERAPY
This proposal addresses Challenge area 7: Enhancing Clinical Trials: 07-OD(ORDR)-102 for the development of a rare disease genetic patient registry. Peripartum cardiomyopathy (PPCM) is a complication of pregnancy occurring in 1:1800 to 1:3500 b
Immune Activation and Myocardial Recovery in Peripartum Cardiomyopathy
This project will mine text from Internet discussion boards, chat rooms, and blogs to identify possible side effects and adverse4 events associated with the use of herbal supplements in breast and prostate cancer.  We will identify sites that s
Mining Internet Conversation For Evidence Of Herbal Association
The title of this project is Improving Childhood Immunization Compliance Using Electronic Health Records. This application addresses broad Challenge Area (05) Comparative Effectiveness Research and specific Challenge Topic, 05-LM-103: Improving
IMPROVING CHILDHOOD IMMUNIZATION COMPLIANCE USING ELECTRONIC HEALTH RECORDS
Does Enhanced School-Readiness Affect Adult Health of African Americans? The purpose of the study entitled Does Enhanced School-Readiness Affect Adult Health of African Americans is to learn if participants in a randomized trial of early childh
Does Enhanced School-Readiness Affect Adult Health of African Americans?
Primary care practice-based research networks (PBRNs) often report high participation rates in their studies. The NIH recognizes PBRNs as important vehicles for translational research projects, strongly supporting them through Clinical and Tran
RECRUITMENT AND RETENTION BEST PRACTICES IN PRIMARY CARE SETTINGS
Recovery Act Limited Competition: NIH Challenge Grants in Health and Science Research (RC1) RFA-OD-09-003 Broad Challenge Area: 15, Translational Science Research Area: 15-MH-109 Prefrontal cortex regulation of higher brain function and complex
Optogenetic control of attention through prefrontal synchrony
The overall goal of this proposal is to advance the development of behavioral and genetic biomarkers for autism and related disorders. While it is clear that autism has a strong inherited genetic component, very large scale genetic studies that
Behavioral and Genetic Biomarker Development for Autism and Related Disorders
This proposal addresses broad Challenge Area (15) Translational Science, and specific challenge topic 15-MH-109 Prefrontal cortex regulation of higher brain function and complex behaviors. Nearly all psychiatric disorders, from schizophrenia to
Elucidation of prefrontal-amygdala neural circuitry with optogenetic techniques
A controversial component of the Medicare Prescription Drug Benefit (Part D) enacted in 2006 is the doughnut hole, a gap in coverage for pharmacy expenditures between $2,250 and $5,100. We recently reported that one in four seniors entered the
Comparing Methods to Pay for Psychotropic Medications for Medicare Beneficiaries
This application is in response to NIMH Challenge Area (08) Genomics, Challenge Topic 08-MH-102, Schizophrenia Interactome. Schizophrenia is a devastating mental illness affecting millions in the US and worldwide, with profound human and econo
NEURON SUBTYPE AND CIRCUIT SPECIFIC PATTERNS OF GENE EXPRESSION IN SCHIZOPHRENIA
Psychiatric Disorders such as alcohol/substance abuse disorders, depression, bipolar disorder and impulsivity-related disorders such as ADHD are among the most significant causes of illness and death in the USA (together affect at least 17% of
Validation of a Functional MRI-based Reward Processing Task as a Non-Invasive Tool to Identify the Role of Ventral Striatal Dopaminergic Abnormalities as Potential Disease Biomarker
This application addresses broad Challenge Area 15-MH-105, Strategies to support uptake of interventions within clinical and community settings: Develop and pilot comprehensive implementation strategies to support the broader uptake of interven
Enhancing Pediatric Psycho Pharmacology in the medical home.
WESTERN INTERSTATE COMMISSION FOR HIGHER EDUCATION
Most college stuents with mental disorders do not receive treatment, and over 80% of those who die by suicide have never made contact with campus mental health services. Knowledge, stigma, and other health beliefs represent significant barriers
Mental Health First Aid for college students: A multi-campus randomized control trial
This application addresses broad Challenge Area (15) Translational Science, Gene x environment x development (GxExD) studies of brain function & mental disorders. Gene x environment epidemiology & psychiatry research studies have only recently
ANXIETY DEVELOPMENT IN 5-HT1A AUTORECEPTOR KNOCKOUT MICE, INTERACTION WITH STRESS
We propose to undertake an empirical investigation of the predictive validity of CBC in the clinical context of racial/ethnic disparities in analgesic preference and adherence to prescription analgesia for cancer pain. Data derived from this st
A Novel Approach to Elucidate Mechanisms for Disparity in Cancer Pain Outcomes
his application addresses broad Challenge Area (02): Bioethics and specific Challenge Topic 02- OD(OSP)-101: Unique Ethical Issues Posed by Emerging Technologies. The current study examines the ethical challenges inherent in participants' consi
Ethics of Control and Consent in Brain Stimulation for Parkinson Disease
This application is designed to identify compounds to treat Charcot-Marie-Tooth type 2E (CMT2E). CMT is the most commonly inherited neurological disorder with a reported prevalence of 1 in 2,500 people worldwide. It is found in all races and et
Identification of  Compounds to treat Charcot-Marie-Tooth type 2E neuropathy
This application addresses broad Challenge Area (06) Enabling Technologies, 06-NS-106: Validating new methods to study brain connectivity. We propose to test a new method that provides substantial improvement over previous Cre-conditional viral
VIRAL BRAINBOW: TRACING BRAIN CIRCUITS WITH CONNECTION ORDER SPECIFICITY
This application addresses Broad Challenge Area (04) Clinical Research, and specific Challenge Topics, 04-NS-103 Developing consortia for clinical research, and is also, in part, relevant to 07-OD(ORDR)-102* Rare disease genetic patient registr
Clinical Research Consortium for Spinocerebellar Ataxias
DESCRIPTION (provided by applicant): This application addresses broad challenge area 05 Comparative Effectiveness Research and specific challenge topic 05-NS-101 Consortia Building for Comparative Effectiveness Research in Clinical Neuroscience
THE HYDROCEPHALUS CLINICAL RESEARCH NETWORK: A  CONSORTIUM FOR PEDIATRIC HYDROCEPHALUS
This application addresses broad Challenge Area (06) Enabling Technologies, and specific Challenge Topic, 06-NS-106: Validating new methods to study brain connectivity. Mapping the structure and function of neural circuits is an important prere
Validating GFP Reconstitution Across Synaptic Partners (GRASP) Methods to Dissect
This application addresses the broad Challenge Area (05) Comparative Effectiveness Research and specific Challenge Topic, 05-GM-101: Anesthesiology Clinical Pharmacology Sepsis Trauma, Burn, and Peri-operative Injury Wound Healing. Traumatic br
DECOMPRESSIVE CRANIOTOMY VERSUS MEDICAL THERAPY FOR REFRACTORY INTRACRANIAL HYPER
This application addresses broad Challenge Area (06): Enabling Technologies, and specific Challenge Topic, 01-OD-101: Development of new tools and technologies to interrogate human mitochondrial function in vivo.    Dysfunction of Mitochondria
MT Function and Dysfunction in Single Neurons in Vivo
This project addresses broad Challenge Area: Enabling Technologies, Challenge Topic   06-HD-101, Improved Interfaces for Prostheses to Impact Rehabilitation Outcomes.  Recent advances in decoding motor intentions and the technology to record po
Model-based Training for BCI Rehabilitation
Challenge Area and Specific Challenge Topic: This application addresses broad Challenge Area (10) Information Technology for Processing Health Care Data and specific Challenge Topic, 10-RR-101*: Information Technology Demonstration Projects Fac
CONCEPT-LEVEL METHODS FOR COMPARATIVE EFFECTIVENESS RESEARCH
Alcohol and nicotine are the most commonly abused legal drugs in the United States. There is a high incidence of nicotine dependence in alcoholdependent individuals, and there is also high rate of problem drinking in habitual smokers. There is
Next-gen sequencing: searching for mechanisms of alcohol and nicotine dependence
Molecular Markers of Alcohol Exposure and Alcohol-induced Tissue Injury:   Alcohol causes tissue injury and organ dysfunction by disrupting the homeostatis interaction between the intestinal microbiome and the human homobiome.  The goal is to i
Systems Biology Approach to Identifying Biomarkers for Alcoholic Liver Disease
Estimates of death rates caused by chronic alcohol consumption, published in 2004 by the World Health Organization, indicate that alcohol accounts for approximately 1.8 million deaths per year. Alcohol consumption leads to addiction and damage
Retinoid Metabolism and Alcohol Induced Disease
GENORM will capitalize on and extend the NIH Toolbox for the Assessment of Neurological and Behavioral Function (a Blueprint for Neuroscience Research Initiative), by adding the collection and storage of DNA to the planned and already-funded  T
GENORM: Collection of Genotypic Data for the NIH Toolbox Norming Sample
This proposal is responsive to the Area of Scientific Priority 'Development of tools to facilitate research on the basic biology of aging' of the National Institute on Aging. Accurate, fast and unbiased methods to detect rare cells in cell susp
(ARRA) CellTrap: A novel solid phase platform for analysis of stem/progenitor cells
The proposed IT infrastructure will provide a state of the art platform on which to build, test, and deploy large scale behavioral intervention studies and advance the science at the intersection of behavioral economics and health. We will prov
Developing Interactive Technologies to Improve Research and Health Behavior
Overall Purpose. Loss of mobility characterized by slowing gait speed, exertional fatigue and exhaustion is a hallmark of age-related functional decline. Current studies have not explained the biological reason for this slowing and loss of mobi
This proposal represents a new interdisciplinary initiative to further develop our unique in vivo spectroscopy tools to measure mitochondrial function in vivo and to increase access to these tools for the scientific community. Mitochondria are
Translational Center for In Vivo Mitochondrial Medicine
The broad aim of this Grand Opportunity Grant is to understand how race-based social stress, racial/ethnic (R/E) identity, and biological functioning contribute to health and healthy aging. Using the Maryland Adolescent Development in Context S
RACE-BASED SOCIAL STRESS AND HEALTH TRAJECTORIES FROM ADOLESCENCE TO ADULTHOOD
In the last several years, a sense of urgency and a renewed interest in the study of radionuclide chemistry and biology have emerged, as threats of nuclear terrorism have become more plausible, and the risk of environmental contamination and hu
Biomimetic Actinide Decorporation:  Characterization and Preclinical Development
Osteoarthritis (OA) is the most common cause of arthritis. Approximately 21 million Americans have physician-diagnosed OA and many more have undiagnosed disease. Knee OA is responsible for as much chronic disability in the elderly as cardiovasc
(ARRA) Genome-wide association study to identify genetic components of knee OA:  The OAI
End stage renal disease (ESRD), one of the most serious and costly complications of systemic lupus erythematosus (SLE), occurs in a sub-set of patients with SLE-related renal involvement.  Factors predisposing to ESRD presumably include both ge
A NATIONAL CONSORTIUM TO EXPLORE THE GENOTYPIC BASIS FOR ESRD IN LUPUS
A recent Agency for Healthcare Research and Quality (AHRQ) executive summary indicated that better systems are needed to determine the relative merits of existing versus new and expensive biologic drug therapies for rheumatoid arthritis (RA). R
Randomized Observation Study of Biologic Therapy for Rheumatoid Arthritis
Despite decades of research, a limiting obstacle to personalizing oncology is identifying correlates of response against a diverse genetic background. For individuals with rare subtypes of human cancers where minimal data exists, this problem i
Canine Hereditary Cancer Consortium: From Bark to Bedside
This project is to use high-throughput genomic sequencing analysis of histone marks and transcription factor binding sites to track the succession of regulatory changes that underlie multipotent progenitor differentiation into T lymphocytes. T
DYNAMIC EPIGENETIC MAPPING OF A STEM CELL DIFFERENTIATION CHOICE
Our goal is to build an infrastructure to discover novel viruses associated with human cancer from next-generation sequencing data, using a sequence-based computational subtraction approach that we developed. This proposed project responds to t
An Infrastructure for cancer virus discovery from next-generation sequencing data
We will study several genetic tests related to colon cancer that may help doctors understand who will get colon cancer and what therapies some patients should receive. We will study who gets tested, how the genetic test result helps people deci
Comparative effectiveness in genomic & personalized medicine for colon cancer
ARRA - Nanotechnology enabled desktop image-guided microbeam radiation therapy system  Today, state-of-the-art radiotherapy provides excellent benefits for patients with early stage and radiosensitive cancers. However, these benefits diminish f
ARRA - Nanotechnology enabled desktop image-guided microbeam radiation therapy s
The goal of this Molecular Target Discovery and Development Center (MTDDC) application is to further develop the innovative functional genomic approaches we have developed at Cold Spring Harbor Laboratory (CSHL) in order to provide biological c
CSHL MOLECULAR TARGET DISCOVERY AND DEVELOPMENT CENTER
Evaluation of a CCR5 Vaccine for HIV Infection in the SIV/Macaque Model. HIV vaccine development has been complicated by the extensive antigenic variation displayed by HIV. As an alternative to targeting the virus, we have developed vaccines ta
Evaluation of a CCR5 Vaccine for HIV infection in the SIV/Macaque Model
This research project will identify biological markers that predict whether adolescents and young adults may become dependent on nicotine when dealing with stressful life events. Ultimately, the results of this project may explain success or fa
Salivary Biomarkers (DNA, RNA and Cortisol), Life Stress and Nicotine Dependence
Psychostimulant (methamphetamine [METH] and cocaine) abuse has reached an epidemic proportion in the US and worldwide, presenting profound socioeconomic, legal and medical problems. In addition, it is a significant comorbid factor for other psy
Novel Ondansetron Formulation for Combination Treatment of Psychostimulant Abuse
HDAC CLASS IIA SPECIFIC PET RADIOTRACERS FOR PET IMAGING OF CNS
This project will generate and validate fourteen strains of mice with fully functional fluorescent mouse nicotinic receptor (nAChR) subunits. These strains will be constructed using the proven and reasonably efficient method of exon replacement
MICE WITH FUNCTIONAL FLUORESCENT NICOTINIC RECEPTOR SUBUNITS
This application is submitted by a group of investigators at 9 sites distributed throughout the U.S. where there are active developmental research programs involving substantial numbers of typically developing children, and neuroimaging investi
CREATING A PEDIATRIC IMAGING-GENOMICS DATA RESOURCE
Debilitating craniofacial skeletal defects, which occur frequently as a result of congenital disorders, trauma, cancer, and surgical interventions, are some of the most challenging problems for reconstruction. While infants demonstrate the abil
Calvarial Regeneration using Biomatrix-Encapsulated Skeletal Progenitors
Virtually all US inhabitants carry detectable levels of bisphenol-A (BPA) in their tissues. Its estrogenic properties have been recognized for decades. Although BPA had been viewed as weakly estrogenic in the past, it is now likely that exposur
PRENATAL BISPHENOL A AND SEXUALLY DIMORPHIC NEURODEVELOPMENT
The broad goals of this project are to describe the mechanism of action of toxic nanomaterials (nanowires by definition have fibrous shape similar to asbestos) both in vitro and in vivo and develop a translational model that can be used for imp
Bioactivity of engineered fiber-shaped nanomaterials
This study is a large-scale basic research project designed to  fundamentally enhance our knowledge of how bisphenol A (BPA) affects the developing immune  system and susceptibility to disease later in life.   The objective of this project is t
DEVELOPMENTAL TOXICITY OF BISPHENOL A AND IMMUNE-MEDIATED DISEASES
Developmental reprogramming is an important mechanism by which early life exposures to environmental agents increase susceptibility to adult disease. For xenoestrogens such as BPA, additional research is required to understand how specific estr
DEVELOPMENTAL REPROGRAMMING OF PROSTATE CARCINOGENESIS BY BPA
Imaging is one of the most powerful tools available to the modern biologist and recent advances in quantitative microscopy and image analysis have greatly accelerated our understanding of many complex and dynamic processes in basic biological
ARRA ImageJ as an extensible image processing framework
The mitochondrion is the center stage for energy metabolism, apoptosis, signaling, and ion homeostasis. Much of what we know about this organelle comes from studying mitochondrial respiratory chain disease (RCD). This devastating disease is due
Defining the genetic basis of human respiratory chain disease
The Connectivity Map 100k project aims to forge a path toward a comprehensive 'functional look-up table' that that links disease biology, genome function and small-molecule action. Such a Connectivity Map would enable researchers worldwide to g
This project will develop new statistical approaches for analysis of next-generation sequence data which is currently being generated to study genetic variation underlying important human disease traits. Our approaches will improve statistical
STATISTICAL METHODS FOR NEXT-GEN SEQUENCING IN DISEASE ASSOCIATION STUDIES.
We propose to use bacterial artificial chromosome (BAC) recombineering to epitope tag 40 transcription factors per year for chromatin immunoprecipitation (ChIP) followed by sequencing to map binding sites genome wide. A major hurdle for the ENC
ENHANCING ENCODE THROUGH A TRANSCRIPTION FACTOR TAGGING APPROACH TO CHIP-SEQ
Children are involuntarily exposed to tobacco both in utero through maternal smoking and during childhood from secondhand smoke (SHS). SHS exposure is associated with important health problems such as low birth- weight, asthma induction, asthma
HIGH THROUGHPUT METHODS TO MEASURE DISPARITIES IN CHILDHOOD EXPOSURE TO TOBACCO
Sarcoidosis is a multiorgan granulomatus inflammatory disorder likely resulting from an exaggerated T-dell response in genetically susceptible individuals. African-Americans are more frequently and severely affected by Sarcoidosis yet few colle
African American Sarcoidosis Genetics Resources
Chronic lung diseases represent a broad spectrum of chronic fibrosing/inflammatory lung conditions that are for the most part poorly responsive to treatment and often fatal.  COPD/emphysema is the fourth leading cause of death in the United Sta
Abstract Women's Health Initiative Sequencing Project (WHISP) The overall goal of this project submitted in response to NHLBI RC2 Topic 'Large-scale DNA Sequencing and Molecular Profiling of Well-phenotyped NHLBI Cohorts' (RFA-OD-09-004) is to
We are creating stem cells from human skin cells (we call these stem cells'induced pluripotential stem cells or iPSCs).  Thus, we are able to make stem cells for individual people.  These iPSCs have the potential to become any cell in the body.
NCE-based strategy for nuclear reprogramming and regenerative medicine
This application proposes development of a unique resource designed to accelerate scientific progress - a National Research Database (NRDB) of Kaiser Permanente (KP) data that will contain clinical information on almost 30,000,000 current and p
The Kaiser Permanente National Research Database
bioethics training and biomedical/medical clinical trials
Internet Publishing and Broadcasting and Web Search Portals
One fifth of America's children grow up in poverty. While there is good evidence that this is harmful to health, achievement, and socio-emotional adjustment, very little is known about the brain basis that mediates the detrimental effects of po
CHILDHOOD POVERTY AND BRAIN DEVELOPMENT: THE ROLE OF CHRONIC STRESS AND PARENTING
The Gulf Coast Transdisciplinary Research Recovery Center for Community Health brings together outstanding academic and public health institutions and centers as a Consortium. The Consortium will coordinate new research studies and projects wit
GULF COAST TRANSDISCIPLINARY RESEARCH RECOVER CENTER FOR COMMUNITY HEALTH
Mental illnesses are common disorders that emerge during childhood and adolescence and many persisting into adulthood, with debilitating consequences. To prevent or intervene in this pathway it is essential to identify premorbid risk factors an
2/2 NEURODEVELOPMENTAL GENOMICS: TRAJECTORIES OF COMPLEX PHENOTYPES
Autism spectrum disorders (ASD) are a group of neuropsychiatric conditions characterized by impairment in the ability to communicate, form relationships, and respond appropriately to the environment. With many autistic individuals having some d
Human autism genetics and activity dependent gene activiation
Schizophrenia is a common, profoundly disabling disorder that carries a heavy burden for patients and families that is the subject of intensive genetic studies, but the study of epigenetic variation, such as DNA methylation, is an essential com
Family-Based Genome-Wide Methylation Scan in Neurocognition and Schizophrenia
Selective Modulation of G-protein coupled receptor (GPCR) signal transduction with biased ligands. One third of today's FDA-approved drugs act on GPCRs, collectively affecting hundreds of millions of people worldwide. Trevena proposes to demons
The long-term objective of our program of research is to improve the cardiovascular (CV) health of inmates by implementation of a state-wide CV risk factor reduction program in prisons. The purpose of the proposed study in male inmates is to te
Biobehavioral Cardiovascular Health Promotion Intervention in a State Prison System
Elucidating the structure and function of brain circuits is arguably this century's greatest scientific challenge. Pioneering studies in invertebrates have established that this challenge can be met by combining anatomical circuit diagrams ('co
This consortium aims to capitalize on an unprecedented 'grand' opportunity to develop a novel and powerful model of Huntington's disease (HD), a fatal neurodegenerative condition with no current treatment. Skin cells from patients with HD can b
Biomarkers for diseases of the nervous system can benefit from advanced proteomic analysis of cerebral spinal fluid (CSF) but some basis biological and analytical parameters of CSF collection, handling, and analysis must first be systematically
dvancing Proteomic Analysis of CSF in Nervous System Diseases
The goals of this research are to elucidate the complex interactions between the transcriptional coactivators CBPjp300, the tumor suppressor p53, and adenovirus ElA. CBP and p300 regulate most transcriptional process in human cells and are esse
Structural Basis for CBP/p300 Transcriptional Regulation
Specific Aims within the requested 24-months of funding: (1) the role and significance of MTA1 in DNA damage response and mechanistic basis of MTA1 regulation of p53 levels; and (2) The molecular basis and significance of MTA1 upregulation of p
This administrative supplement seeks funds to support one undergraduate student’s summer research experience.  The primary purpose is to introduce an undergraduate student to molecular cancer biology research.  The student will be trained in
This and several other NIH grants involve quantification of molecular damage products using sensitive chromatography-coupled mass spectrometry methods.  Our current one-dimensional approach to resolving the mixtures of damaged molecules by hi
Chemistry and Biology of Deoxyribose Oxidation
Decreased levels of cell cycle inhibitor p27Kip1 due to excessive degradation occur in a variety of aggressive human tumors. Since reduced p27 expression has been associated with a poor prognosis in many human cancers and resistance to certain
Mechanisms of p27Kip1 Proteolysis in Cancer Cells
Gliomas are the most common type of human brain tumors. Based on clinical and pathological criteria, they can be classified into four grades. The grade III and IV gliomas are malignant tumor. Grade IV glioma is commonly known as glioblastoma, w
THE TSC-MTOR PATHWAY IN CELLULAR AND ORGANISMAL ENERGY METABOLISM
During the period of the parent grant we have reported that the ability of chronic lymphocytic leukemia (CLL) cells to avoid apoptosis and accumulate in the circulation of patients is the result of aberrant stabilization of bcl-2 mRNA by the pr
Drug-Induced Destabilization of Bcl-2 mRNA
Notice of Availability of Recovery Act Funds for Administrative Supplements NOT-OD-056.
Role of Polyamines in MYCN-Amplified Neurolblastoma
This research investigates how chronic infection by the gastric bacterium Helicobacter pylori causes gastric cancer, the second leading cause of cancer death worldwide. Specifically, it focuses on how H. pylori, the main cause of gastric cancer
P27 & APOPTOSIS RESISTANCE IN GASTRIC CANCER
Due to contracting delays, no Notice of Award has been approved at the Stanford School of Medicine as of this date (03/23/10).  As such, while the study remains open, its progress is delayed pending access to funding provided through the NOA.
Telomeres, Telomerase and Tumor Progression
Radiofrequency (RF) and microwave ablation techniques are interstitial, focal ablative therapies that can be used in a percutaneous fashion. They permit in situ destruction of hepatic, renal and prostatic tumors. However, local recurrence rate
ARRA Real-Time Ultrasonic Monitoring of Tumor Ablation, ARRA Administrative Supplement
This administrative supplement proposes to accelerate the pace of research under the existing scientific aims of our successful project, ?NSAID and COX/PG Metabolism and Colorectal Cancer? (R01 CA112516) by incorporating more complete informati
NSIAD and COX/PG Metabolism and Colorectal Cancer
Of the over 200,000 men estimated to be diagnosed with prostate cancer in 2010 in the U.S, almost one half will undergo radical prostatectomy (RP) for treatment of their disease. As many as 25% or more men who undergo this treatment will experi
GENETIC SUSCEPTIBILITY FOR PROSTATE CANCER PROGRESSION
Almost without exception, patients with localized tumors have better prognoses than patients with metastatic disease. The long-range goal of our studies is to develop safe, effective, systemic treatments for metastatic solid tumors. The basis o
NEURAL PROGENITOR CELLS AS CANCER THERAPY VECTORS
ARRA - Effect of Male Circumcision on Penile HPV Infection  As an administrative supplement for the ongoing study of the Effect of Male Circumcision on Penile HPV infection RO1 CA114773-01 grant, we will newly hire a full-time post doctoral stu
ARRA - Effect of Male Circumcision on Penile HPV Infection
Human leukemia/lymphoma is often associated with acquisition of a constitutive activation of the Jak/STAT pathway. Jak activation leads to increased survival and increased proliferation of tumor cells as well as metastasis. While in some instan
Uncoupling of Jak/STAT in HTLV-1 associated leukemia
For two decades, PSA testing has been employed routinely in clinical practice. The outstanding success of this approach, with its emphasis on early detection of malignancy, can be judged by one key distinction between today's prostate cancer pa
Characterizing Prostate Cancer By ex vivo MRS Signatures
Tumors arising from non-neural or glial tissue of the brain ('gliomas') constitute one of the most lethal human cancers. Few case-control studies of glioma have been undertaken, and the etiology of the tumor is largely unknown. However, the des
Southeast Region Case-Control Study of Adult Glioma
The quality of life and survival for cancer patients are considerably threatened by liver metastases. While surgical resection is often not possible and systemic chemotherapy is largely ineffective, promising interventional therapeutic techniqu
Real-time 3D MRI Technologies for Therapy and Diagnosis, ARRA Administrative Supplement
, we will focus on the effects of isothiocyanates alone or in combination with the phenolic compounds curcumin, on the inhibition of carcinogenesis by testing the hypothesis that isothiocyanate and curcumin alone and/or in combination prevent c
Chemopreventive Signaling Mechanisms in Prostate Cancer
In line with the goals of the ARRA, we are requesting supplement funding for the hiring of two fellows to (a) advance the supply of functionalized metallofullerenes (f-MFs) and (b) accelerate tumor targeting basic science results to date. One f
Metallofullerene Nanoplatform for Imaging & Treatment
As a supplement to our parent grant titled “Commonly Used Medications and Breast Cancer Recurrence”, we propose a comparative effectiveness study of adjuvant oral endocrine therapy (i.e., tamoxifen (TAM) and aromatase inhibitors (AIs)) for
Commonly Used Medications and Breast Cancer Recurrence
DESCRIPTION (provided by applicant): Great effort has been made in developing tumor-targeted gene delivery, but no attention has been given to targeting the therapeutic gene products that are transcribed and translated from genes transfected in
Gene-Products Auto-Targeting to Tumor Vessels
Melanoma is the most rapidly increasing malignancy in the United States. While it accounts for only 4% of all skin cancers, it is responsible for nearly 80% of all skin cancer deaths. If detected early, the disease is easily treated; however, o
A High-Throuput Model for Human Melanoma
Bladder cancer is the most common urologic malignancy and is responsible for an appreciable number of deaths each year in the USA. Aside from tobacco smoking and certain occupational exposures, the etiology of this malignancy remains largely un
THE MOLECULAR EPIDEMIOLOGY OF BLADDER CANCER
With continuous improvements in cancer treatment, there is a growing population of long-term cancer survivors who are at a significant risk for late effects induced by ionizing radiation (IR) and chemotherapy, such as residual bone marrow (BM)
Cancer Therapy-Induced Long-Term Bone Marrow Injury (ARRA Funds for Administrative Supplement)
DESCRIPTION (provided by applicant): The primary goal of this research is to understand communication, comprehension and decision-making in Phase I childhood cancer trials. The project will take place at 6 of the most active Phase I pediatric p
INFORMED CONSENT IN PEDIATRIC PHASE I CANCER TRIALS
The combined use of TLR and CD40 agonists together with tumor antigen is a novel vaccine platform that elicits robust immunity resulting in the effective eradication of pre-existing cancer. The synergy that is manifested by the combined adminis
Synergy of the innate and acquired immune responses in tumor immunology
Receptor tyrosine kinases (RTKs) have been shown to be important as therapeutic targets againstlung cancer. However, even with the RTK epidermal growth factor receptor inhibition, the responsewith small molecule inhibitors is at best 5%-15% in
STUDIES OF A NOVEL THERAPEUTIC TARGET IN NON-SMALL CELL LUNG CANCER (NSCLC)
This grant has enabled the creation of software that contributes important capabilities for identifying mutated and modified proteins that are characteristic of cancer samples. This supplement will hire a new programmer tasked with adding three
New Proteomic Algoriths to Identify Mutant or Modified Proteins
DESCRIPTION (provided by applicant): Despite impressive advances in understanding cancer etiology and the development of novel therapeutic approaches, the most effective therapies for solid malignancies (carcinomas) remain surgery and radiother
IKK AND THE CONTROL OF PROSTATE CANCER METASTASIS
We submitted this administrative supplement in response to the request for administrative supplements through the American Recovery and Reinvestment Act (ARRA).   With the funds we are:1. Accelerating science by adding comparative effectiveness
QUIT-PRIMO:Web-delivered Clinical Microsystem Intervention for Tobacco Control
was dedicated to investigating the overall process of intravasation, the entry of primary tumor cells into the vasculature of the host organism. As part of Specific Aim 1 of the parent grant, it was hypothesized that intravasation itself can b
A Cellular and Molecular Analysis of the Intravasation Step in Tumor Metastasis
Current diagnostic tests cannot reliably determine prostate cancer extent (volume and location) or biological aggressiveness. Our long term goal is to develop a non-invasive imaging technique that accurately assesses the clinical significance o
Multi-parametric MRI Determination of Prostate Cancer Aggressiveness and Extend
The goal of our studies is to develop a quantitative understanding of tumor metastasis. As cell migration is the central part of metastasis, we are developing quantitative experimental and computational methods to study migration in three dimen
QUANTITATIVE ANALYSIS OF TUMOR CELL MIGRATION IN THREE DIMENSIOINAL MATRICES
The goal of this summer program is to offer an intensive laboratory experience for an undergraduate student, and to speed up our research progress in developing nanomedicine. Ms. Catherine Chen, a sophomore major in chemistry from Rice Universi
Dendritic Nanomedicine for Cancer Imaging and Treatment
This study develops novel approaches based on the p14ARF tumor suppressor and Spermidine-CoA-based inhibitors of histone acetylation to improve cellular responses to topoisomerase I-targeted chemotherapies and reverse therapy resistance, a majo
Regulation and Function of the p14ARF/topoisomerase I Complex in Cancer
It has been suggested that the small fraction of tumor cells capable of initiating local or distant recurrence exhibit properties of stem cells, and that identification and molecular characterization of putative cancer stem cells will lead to b
HUMAN BREAST CANCER STEM CELL SURROGATES
DESCRIPTION (provided by applicant): Proteolytic processing of proenkephalin (PE) is required to produce active enkephalin opioid peptides that regulate analgesia, behavior, and immune cell function. It is, therefore, critical to define the mul
BIOSYNTHESIS OF ENKEPHALIN OPIOID PEPTIDES
Priming is a class of ubiquitous behavioral phenomena defined as progressive increase in the speed and strength of behavioral responses to repeated stimuli. Priming has a clear mnemonic component, i.e., responses remain potentiated for a consi
NEURAL BASIS OF BEHAVIOR PRIMING: INDUCTION AND MEMORY
Cocaine and methamphetamine are leading drug threats in the U.S. today, yet no effective treatments for their abuse are available.  Parent grant information: The specific aims of the parent grant tests the hypothesis that beta receptors represe
Synthesis and Evaluation of Sigma-Active Cocaine Antagonists - Equipment
Drugs of abuse induce persistent adaptations in neuronal function that are driven in part by the drug-induced expression of new gene products which modulate synaptic function and neuronal excitability. My laboratory has been studying the role o
EPIGENETIC REGULATION OF TRANSCRIPTIONAL REPRESSION BY DRUGS OF ABUSE
This grant provided a summer research experience for one science educator in health-related scientific research for Parkinson's disease.
D3 Receptor Compounds for the Treatment of Psychostimulant Abuse
The rationale and methods for the parent study are as follows: The vast majority of persons with substance use disorders go undetected and untreated. Proactive screening, brief intervention, and referral for treatment approaches (SBIRT) have tr
Computer vs Therapist-Delivered Brief Intervention for Drug Abuse in Primary Care
We will determine the neurotransmitter critera of presence and synthesis by identifying dopamine located in hair cells and/or efferents and localize its enzymes of synthesis in rat inner-ear sensory epithelia. We will also identify and coimmuno
This administrative supplement will allow us to accelerate the tempo of our research by hiring assitional staff. The long-term objectives of this project are to investigate the mechanisms regulating neural regeneration and to develop strategies
Properties of Olfactory Receptors - Neutral Regeneration
This proposal examines the processing and encoding of temporal information in a relatively well understood auditory system. Analysis of how animals process temporal information has uncovered many common principles: Despite their different neura
CELLULAR MECHANISMS UNDERLYING SOUND LOCALIZATION
The sense of taste is the primary sensory system that determines whether a food or beverage will be ingested or rejected. Taste also influences food processing by the digestive system. Consequently, understanding the mechanisms underlying this
NORTHEASTERN OHIO UNIVERSITY COLLEGE OF MEDICINE
This grant provided summer research experiences for 2 undergraduate college students in health-related scientific research.
Auditory Information Processing in the Midbrain: Modulation by the Amygdala/Trans-NIH Recovery Act Research Support
Odor information is encoded by selective activation of olfactory receptors and mapped topographically to glomeruli in the olfactory bulb. Our broad, long term objective is to understand dendritic and synaptic signaling mechanisms in the bulb th
DENDRITIC SIGNALING IN THE OLFACTORY BULB
Almost all organisms that possess an olfactory system exhibit a similar organization in their primary olfactory neuropil.  Olfactory receptor neurons (ORNs) that detect volatile molecules in the periphery extend axons into the brain where they
NITRIC OXIDE SIGNALING IN A MODEL OLFACTORY SYSTEM
Human adults can improve their auditory perceptual skills through practice, making perceptual training a promising tool to treat communication disorders. However, the perceptual-training regimens currently used are costly in time, as well as in
Twenty-eight million Americans suffer from hearing impairment. By age 80 about half the population has age-related hearing loss (presbycusis). While some degree of presbycusis can be ascribed to environmental exposures, a significant fraction i
The long term goal of our research is to develop an acoustically-based, explanatory model of the communication deficit in dysarthria that can be used to guide and justify treatment decisions. Toward this end, the proposed Phase I treatment proj
ARRA: Therapeutic Approaches to Dysarthria:  Acoustic and Perceptual Correlates
Many early-implanted children with cochlear implants (CIs) today attend mainstream schools alongside their NH peers.At present, information about how young, NH children process sounds at a psychophysical level is relatively sparse in the field.
Complex Auditory Processing with Cochlear Implants
DESCRIPTION (provided by applicant): Gravity is an important context for adapting the angular vestibulo-ocular reflex (aVOR) by visual-vestibular mismatch. Maximal gain changes occur in the position of adaptation and decrease, as the head is or
CONTEXT-SPECIFIC SPATIAL ADAPTATION OF THE VOR
The nervous system processes sensory stmuli, such as sounds, by encoding them into a sequence of neural representation (deCharms and Zador 2000).  The cortical representation is a highly processed version of the auditory nerve input from which
Functional Microcircuitry Underlying Sound Processing in the Primary Auditory Cortex
Research Equipment for the Advancement of Science: This supplement grant is to purchase equipment that will significantly increase our capacities to pursue the research aims of the parent application R01-DC005808 ('Auditory-Vocal Interaction Me
Vestibular schwannomas in humans can cause morbidity associated with hearing and balance loss, facial paralysis and paresthesias, and occasionally life-threatening brainstem compression. Vestibular schwannomas can be divided into three general
(ARRA) Phenotypic determinants of vestibular schwannomas
The nasal cavity in mammals houses distinct chemosensory epithelia including the main olfactory epithelium, the vomeronasal epithelium and the trigeminally innervated respiratory epithelium (so-called 'non- sensory' epithelium) (Finger et al.,
Multiple Mechanisms of Nasal Chemoreception
The supplement allows us to perform experiments related to the first specific aim of the grant but which were not proposed originally.  Our novel findings related to the linearity of central vestibular neuronal responses will be further develop
CENTRAL NEURONAL ACTIVITY IN VESTIBULAR COMPENSATION
The primary objective of this application is to identify essential oromotor skills that children obtain during early speech development and factors that contribute to individual variation in the course of speech development. The specific aims a
Afferent Synaptic Transmission in the Mammalian Cochlea: Parent Grant: This proposal seeks to investigate mechanisms of synaptic transmission at the inner hair cell (IHC) afferent synapse in the mammalian cochlea. In the inner ear, sound signal
AFFERENT SYNAPTIC TRANSMISSION IN THE MAMMALIAN COCHLEA
These purchases will permit us to collect more data and will increase the efficiency of our work. The real time analysis of neural growth will speed up our testing of individual genes that will be assessed for the regrowth and reinnervation of
and similar processing disorders, where the LOG may play an important role in detecting signals in a noisy background.
Physiological and Behavioral Assessment of Lateral Efferent Function
The remarkable sensitivity and specificity of mammalian olfaction arises from the contributions at the molecular, cellular and tissue levels to establish a sensory organ. One of the most important components in this developmental process is the
MOLECULAR MECHANISMS OF OLFACTORY RECEPTOR CHOICE
'Basic and Clinical Studies of Noise-Induced and Age-Related Hearing Loss'  Our goal is to understand how these structures are cycled in normal ears and whether they are replaced or regenerated after acoustic trauma. Such work should improve ou
ARRA-Basic & Clinical Studies of Noise-Induced and Age-Related hearing Loss
The long term goals of our laboratory are to understand the molecular mechanisms responsible for cell fate specification and sensory patch formation in the developing mammalian inner ear. Progress toward understanding these essential aspects of
Molecular Embryology of the Mammalian Inner Ear - Summer Students
This project will accelerate the progress of the funded research, increase the focus on a common vistibular disorder, increase the statistical power for some experiements of the parent grant for some experiments, ask a clinical question that ma
Epidemiologic Research on Screening for Vestibular and Balance Disorders
Abstract Bilateral loss of vestibular function (inner ear balance sensation) due to ototoxic hair cell injury is disabling, with patients suffering disequilibrium and inability to maintain stable vision during head movements typical of daily li
ELECTRICAL STIMULATION TO RESTORE THREE DIMENSIONAL VESTIBULAR SENSATION
Infections due to Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis, are the leading causes of morbidity and mortality in both HIV infected and immune competent people. A major factor contributing to virulence of Mtb is its
Mycobacterium tuberculosis Replication and Proliferation
University of Texas Health Science Center
Despite the advent of new “targeted” drugs for the treatment of blood cancer 'leukemia'), many patients will fail therapy and relapse.  The goals of this proposal are to develop and test new leukemia therapies, based on transfusion of cells
Novel Cellular Therapies for Ph+ Leukemia
This proposal is submitted in response to the announcement ?NIH Small grant Program (RO3)-PA-06-180?. The goal of this proposal is to understand the role of transcription antitermination and melting of nucleic acid secondary structures in bacte
Transcription antitermination by OB-fold family proteins
This funding will enable the Principal Investigator and other SOM faculty to acquire a Multi-Photon Microscope in order to facilitate neuroscience research through the Imaging Core Facility at WSU.  The system is built from components from diff
Multi Photon Laser Microscope for Neuroscience Research Imaging Core Facility
Purchase of a 700MHz NMR Spectrometer for Liquid Applications Project Summary Solution nuclear magnetic resonance (NMR) spectroscopy is one of the most powerful spectroscopic tools available to the synthetic chemist for the elucidation of the s
PURCHASE OF A 700MHZ NMR SPECTROMETER FOR LIQUID APPLICATIONS
New Cyclotron for Translational PET Imaging  Project Summary: We herein request for a replacement Cyclotron for the Center for Biomolecular Imaging (CBI) program at WFUHS. The CBI is a centralized imaging resource at our institution that suppor
New Cyclotron for Translational PET Imaging
Title: Establishment of a High performance UPLC-QSTAR Elite Proteomics Platform at University of Florida. This project is to establish an UPLC-QSTAR Elite Proteomics Platform at University of Florida to enhance the mass spectrometry technology
Establishment of a High performance UPLC-QSTAR Elite Proteomics Platform at University of Florida
The Zeiss LSM 710 Laser Scanning Confocal Microscope will be a critical tool for NIH investigators at the University of Iowa. The proposed microscope will replace a failing system that over the past 18 months has supported the confocal imaging
Request for Funds to Purchase a Replacement Laser Scanning Confocal Microscope
The objective of this NCRR Shared Instrument Grant application is to obtain funding to purchase a Thermo Electron Orbitrap XL-ETD mass spectrometer for the W.M. Keck Biomedical Mass Spectrometry Lab (MS Core) at the University of Virginia's Sch
Thermo Electron LTQ Orbitrap XL - ETD Mass Spectrometer
Obesity and diabetes are complex disorders that have emerged as major health concerns worldwide.  The complexity inherent in these disorders with respect both to their pathogenesis and metabolic consequences has heightened the need for interact
Design-based stereology has become the required method for insuring that cell number and volume estimates in brain (and other) tissue sections are unbiased. Expressed user need underlies this proposal to purchase an integrated confocal stereolo
A CONFOCAL STEREOLOGY MICROSCOPE FOR UNM'S FLUORESCENCE MICROSCOPY CORE
Confocal Laser Scanning Microscope LSM 710 #5- ARRA This was a grant to purchase a greatly needed confocal laser scanning microscope(CLSM) for use in a microscopy core facility that provides service to hundreds of scientist on the medical campu
Confocal Laser Scanning Microscope LSM 710 #5- ARRA
Funding support is requested for a MALDI-TOF-TOF mass spectrometer with associated liquid chromatograph and spotting robot that are essential to many NIH-funded research programs. To ensure maximum availability, proper maintenance and best use
Purchase of a MALDTI-TOF-TOF Mass Spectrometer
This proposal requests funds to purchase a NanoZoomer Digital Pathology System for the use of 9 investigators at the University of south Florida in Tampa.  The NanoZoomer was selectedowing to it's a) capacity to collect images using fluorescenc
Dept. of Molecular Pharmacology and Physiology
This is a request to purchase a high resolution, high mass accuracy tandem mass spectrometry system for proteomics analyses. The mass spectrometer will be equipped with a nanoflow liquid chromatography system and chip based electrospray interfa
Individuals selected for the Scholarship for Disadvantaged Students at Virginia Commonwealth University were citizens, nationals, or lawful permanent residents of the United States.  Students that submitted documentation showing the family annu
Funding scholarships for medical students.
Scholarships for Health Professions Disadvantaged Students (SDS - ARRA) (Allopathic)
Financial Assistance for Occupational Therapy BS/MS Students Attending an Urban Public College
Interest in changes and deficiencies of the immune system during the aging process has gained momentum in recent years. It is now realized that an adequate comprehension of healthy aging requires more foundational knowledge about how to enhance
Our programmatic goal is to provide for an integrated career development pathway in clinical aging research for both physician and non-physicians. We are requesting funds to support establishment of a geriatric fellow / post-doctoral training p
Training Program in Gerontological and Geriatric Medicine
Ebola and Marburg viruses belong to the family Filoviridae and can cause fatal hemorrhagic fevers characterized by widespread tissue destruction with an incubation period of 4-14 days. Because of the safety concerns, these viruses are designate
Screening and Development of Anti Filovirus Entry Inhibitors
Following the anthrax bioterror attacks in the US in 2001, awareness of the potentially devastating effects of attack with a bioweapon led to recognition of the need to take action and prepare against possible future nefarious events. F. tulare
Advancement of New Live Attenuated F. Tularensis Type A Vaccine Strains
The viral hemorrhagic fevers (VHFs) pose a threat as possible bioterrorist agents as well as to populations in sub-Saharan Africa where many VHFs are endemic. The non-specific clinical presentation of the VHF, makes them extremely difficult to
Multiplex Mass Tag PCR for African Viral Hemorrhagic Fevers
In nature, cytotoxic T-cells are responsible for identifying cells that display foreign antigens and killing them. However, T-cells do not only respond fully to typical foreign antigens but also show responses to self in the periphery in the fo
Biophysical Analysis of T-cell discrimination among classes of self-ligands
The Bringing Immunity to Every Community initiative addresses an unmet need by developing a partnership between the Centers for Disease Control and Prevention (CDC) and the national nursing community.  The ANA brings to the partnership its netw
ARRA-Partnerships to Address IMM.  Training for Nurses, Other Health Staff, COAL
Human physiology and health is highly dependent on the activities of billions of microorganisms that inhabit multiple niches within and on the human body. Few of these microorganisms have been characterized, in large part because the majority i
Construction of a Reference Sequence Data Set for the Human Microbiome Project
We propose that Cancer is a dynamic complex multiscale system that can only truly be understood via the integration of theory and experiments. The goal of the proposal is to use such an integrated approach to better understand, predict and trea
The Physical Microenvironment in Cancer Biology and Therapy
Infectious diseases, such as influenza, lead to high morbidity and mortality in elderly populations. In addition, the efficacy of vaccines is also significantly reduced for elderly populations, leaving them much more vulnerable to infection. We
C. albicans is an opportunistic human fungal pathogen that causes mucosal, cutaneous, and systemic infections including oropharyngeal candidiasis (OPC), the most frequent opportunistic infection among patients suffering from AIDS. Fluconazole a
Novel Azole Resistance Mechanisms in Candida albicans
Characterizing unique virus-host interactions is key to understanding pathogenesis and developing therapeutics to block the virus life cycle.  Because of their intimate associations with host cells, viruses have also been exploited as tools for
RNA Splicing Control in Rous Sarcoma Virus
Neurological recovery is limited in many clinical situations by the inability of adult brain and spinal cord to grow axons and form new connections to replace lost function. This Project seeks to define the molecular limitations on nerve fiber
Molecular Determinants of Adult CNS Axonal Growth
Statement of Purpose: Identifying novel mechanisms of cell death regulation for stroke, heart disease and cancer
The role of mitochondrial VDACs in apoptosis
This research project pursues the hypothesis that the fatty acid-binding proteins, A-FABP and E-FABP, link metabolic and inflammatory pathways in leukocytes and act as regulators of both innate and adaptive immune responses.  Specific Aim 1 is
ARRA Fatty acid binding proteins in macrophage function
Improvement of laboratory based detection and characterization of bacterial agents of vaccine preventable diseases including pertussis and meningitis in public health laboratories in the US.
The work performed will support the implementation of immunization activities funded through ARRA, including reaching more children and adults with immunization; enhancing information, education and communications about immunization; and streng
To supply flu vaccines for CDC's adult vaccine contract
Energy conservation updgrades at City Hall
Energy Conservation Updgrades at City Hall
CS Fr. ON WESTGATE DRIVE, FROM US 83 To. SUGARCANE RD (MILE 9 N RD);  RECONSTRUCT AND WIDEN TO 4 LANES
Pavement & Rehabilitation, North X, 2009
City of Rehoboth Beach Boardwalk Major Reconstruction
Old Lancaster Pike Streetscape Improvements (Hockessin) - TE; DelDOT Administered
Conditions have been optimized for conducting chromatin immunoprecipitation assays with low background and sufficient resolution to give clear signals after ChIP-Seq analysis. We anticipate commencing ChIP-Seq analysis of osteoblast differentia
MAP KINASE REGULATION OF OSTEOBLAST FUNCTION
The supplement will provide funding for a post doctoral scientist to work on the project at the sub-award institution. The pace of research will be accelerated by this hire.   A key event in the secretagogue stimulation of both the fluid and pr
[CA2+]I AND SECRETORY DYNAMICS IN PAROTID ACINAR CELLS
.  This supplement provides short-term research experience for two college graduates during the summer preceding their entry into the first year of the DDS program at Baylor College of Dentistry.  The purpose of the supplement is to:  1. recrui
The focus of this supplement is to determine if cathepsin K is essential for proper dental enamel formation. The parent grant focused on defining how enamelysin (matrix metalloproteinase-20; MMP20) processes enamel proteins and focused on deter
ENAMELYSIN PROCESSING MECHANISMS IN AMELOGENESIS
This grant provided a summer research experience for two college studnets, science educators in health-related sceintific research. The major task of this administrative supplemental grant application is to provide basic research training oppor
GLYCOSYLATION & FUNCTION OF AN ORAL STREPTOCOCCAL ADHESIN
The combination of technological advances in Dental materials and increased demands in quantity and quality by a burgeoning population of dentate elderly has resulted in the production of new Dental restoration systems at an unprecedented pace.
This Administrative Supplemental Revision is in response to notice number (NOT-OD-09-058). Notice Title: NIH announces the availability of recovery act funds for administrative revision applications. The parent grant, R01DE018549, has the objec
Role of trpv4 in trigeminally mediated nociception
Regulation of Sinusoidal Perfusion in Shock  Altered hepatic vascular regulation is a common event following shock or sepsis.  Recent work shows that this is related to increased constrictor response to endothelin that is associated with decrea
Regulation of Sinusoidal Perfusion in Shock
Lipid Transport in the Intestine Fatty acids (FA) and monoacylglycerol (MG) are the primary hydrolytic products of dietary triacylglycerol (TG). Substantial gaps remain in our understanding of the basic mechanisms of MG and FA assimilation by t
A major challenge facing biomedical research is to determine how the network of interactions involving gene regulatory proteins is controlled in the context of the natural environment inside living cells, and to understand how disease processes
Specific Repression of Prolactin Gene Expression
DESCRIPTION (provided by applicant): The low-affinity Na+/dicarboxylate cotransporter NaDC1 is found on the apical membrane of the renal proximal tubular epithelium, where it plays an important role in the reabsorption of citric acid cycle inte
MOLECULAR MECHANISM OF RENAL NA+ DEPENDENT COTRANSPORT
Autosomal Dominant Polycystic Kidney Disease (ADPKD) is caused by mutations in the genes encoding polycystin-1 and/or polycystin-2, but results in epithelial cells with disrupted adherensjunctions and compromised beta-catenin signaling pathways
PATHOLOGIC MECHANISMS OF POLYCYSTIC KIDNEY DISEASE
DESCRIPTION (provided by applicant): Multiple cell types are involved in the development and persistence of chronic inflammatory response. This also occurs in inflammatory bowel disease (IBD), where long-standing activation of immune and non-im
Cell Interactions in the Inflamed Intestinal Mucosa
DESCRIPTION (provided by applicant): In the past funding period, we have performed novel studies demonstrating an important role for Wnt signaling as an inhibitor of adipogenesis in cultured preadipocytes and in transgenic mice. Our studies hav
Regulation of adipocyte differentiation and metabolism
Therapeutic liver repopulation (TLR) is a process similar to bone marrow transplantation (BMT) resulting in replacement of > 90% of hepatocytes in the recipient liver by transplanted donor cells. Although TLR to date has been achieved experimen
Transplantation Assay for Liver Repopulating Cells
Renal failure is increasing at the rate of 6% with a cost of 16 billion dollars per year; thus developing new therapies for kidney disease is of paramount importance. In the previous renewal, we demonstrated that a loss of constitutive expressi
Endothelial Cell in Progressive Renal Disease
We will continue studies of the role of CEACAM1 in insulin metabolism. CEACAM1 is a substrate of the insulin receptor kinase in the liver. In the first four years of funding, we have demonstrated that hepatic CEACAM1 plays a pivotal role in the
An elevation in the [Ca2+]i following secretagogue stimulation plays a fundamental role in underlying digestive enzyme secretion from the exocrine pancreas. The increase in [Ca2+]i is a tightly regulated event and exhibits characteristic tempor
PANCREATIC FUNCTION: G-PROTEIN MEDIATED CA2+ SIGNALING
Abnormal glomerular cell-extracellular matrix (ECM) adhesion, cytoskeleton organization and apoptosis are key factors in progressive glomerular failure.  The goal of the parent project is to elucidate the molecular mechanisms by which glomerula
The PINCH-ILK-parvin Complexes in Glomerular Cells
Choline is an essential nutrient that is derived from the diet, as well as from de novo synthesis of phosphatidylcholine catalyzed by phosphatidylethanolamine N-methyltransferase (PEMT). The human dietary requirement for choline has significant
ARRA - Human Requirements for the Nutrient Choline.
The colonic epithelium is subjected to a variety of challenges that result in a wide range of diseases and disorders, including colitis, polyp formation and malignant transformation. We have identified the Let-7a3 and Let-7b microRNAs, which ar
MicroRNAs and chromosome 22q in the colon
There were two supplements for this award. The first was to support the addition of an undergraduate student during the past summer. The student was hired and worked effectively on this program. The student's work focused on processing brains f
This supplement allows for characterization at a cellular level the events leading to the early increases in matrix stiffness that precede fibrosis; specifically to determine which cells in the liver secrete collagen and elastin immediately aft
TGF-beta, Matrix, and myofibroblasts in hepatic fibrosis
The short chain fatty acid butyrate (NaB), present in high concentrations in the colonic lumen principally from the fermentation of dietary fiber, plays a physiological role in colonic homeostasis. This involves maintaining an equilibrium not o
Colon Cell Differentiation : NAB and MUC2 Gene Expression
Currently there is a major need in hematopoietic stem cell (HSC) transplantation to develop reduced intensity regimens that do not cause DNA damage and associated toxicities and that allow a wider range of patients to receive therapy.  Cytokine
for transplantation. The incidence of hepatic steatosis is 10 to 25% based on autopsy studies and donor liver biopsies. It is clear that methods that would salvage discarded donors because of severe steatosis could significantly reduce the num
Metabolic Engineering for Improved Liver Function
The Na+/H+ exchanger isoform 3 (NHE3) constitutes a major Na+ transport process, which moves a large quantity of salt and water from the mucosal side toward the serosal side. Our long-term goal is to understand the molecular mechanisms that con
REGULATION OF NA ABSORPTION BY NHE3 IN THE INTESTINE
This research will advance new concepts in physiological and clinical translational research related to gastrointestinal motility disorders including diabetic gastroparesis. These concepts resulted from biochemical and physiological experiment
Nitrergic Neuro-smooth Muscle Transmission in the Gut
Training of summer students for biomedical research.  Protein biosynthetic quality control systems orchestrate the elimination of newly synthesized proteins that fail to achieve their correct native structure. Our goal is to elucidate how these
Post-translational Surveillance of Genome Expression -NOT-OD-09-060
The goal of this project is to produce a murine model for neonatal onset N-acetyl-L-glutamate synthase (NAGS) deficiency by creating a mouse in which the NAGS gene has been disrupted. Defects in urea cycle genes such as NAGS affect approximatel
N-acetylglutamate Synthase: Structure, Function & Defects
DESCRIPTION (provided by applicant): The small intestinal epithelium is organized into flask-like glands (crypts) that contain intestinal stem cells and finger-like projections (villi) covered by differentiated cells. A constant process of cell
Cell: Cell Interactions During Late Intestinal Development
Social stress is prevalent in many facets of modern society. Epidemiological data suggest that stress is linked to the development of overweight, obesity and metabolic disease. We have established the visible burrow system (VBS) model of chroni
Stress and Body Weight Regulation (Administrative Supplement)
Antimitochondrial antibodies (AMA) are unique among autoimmune serologic reactants because of their extremely high association with primary biliary cirrhosis (PBC). The AMA is not only highly directed, but also very specific to the lipoyl domai
Subproject for Institution # 06-002766: Xenobiotics and Primary Biliary Cirrhosis
and will be completed this summer.  The Airman plans to enter Medical School in the Fall of 2010 and is looking for a 1-year research position in the interim.  We propose to hire the Airman as a research assistant who will work on an NIH-funde
Autosomal dominant polycystic kidney disease (ADPKD), affecting 500,000 Americans, is the most common potentially lethal genetic disease and is characterized by cyst overgrowth that destroys the kidney.  Protein synthesis and delivery are essen
The Exocyst in Synthesis, Cystogenesis and Tubulogenesis
The focus of the proposed studies is to examine the interaction and modulatory activity of EBP50 on all aspects of PTH1R cycling. To the best of our knowledge, we are the only laboratory comprehensively analyzing the regulatory effects of EBP50
EBP50 Regulation of PTH Receptor in Bone and Kidney
This proposal will explore genetic pathways that specify the commitment of embryonic mesoderm toward hematopoietic fate in model organisms like the fish and mouse, in order to identify mechanisms that can be engineered to drive hematopoietic st
DESCRIPTION (provided by applicant): Steroid receptors (SRs) are hormone-activated transcription factors controlling tissues-specific gene expression and therapeutically important physiologies. In their inactive states, these receptors are know
TPR Proteins in Steroid Receptor Signaling & Physiology
Gastric cancer develops from preneoplastic metaplsias. Our present grant is focused on identifying and the mechanisms responsible for induction of metaplasia and characterizing possible markers of induced metaplasia in mouse models of acute and
Mechanisms of Gastric Mucous Cell Metaplasia
Gallstone pancreatitis is common and is potentially fatal. Enteral exclusion of bile-pancreatic juice by the stone causes feedback hyperstimulation of the exocrine pancreas that induces pancreatic overproduction of acute inflammatory mediators.
Gallstone Pancreatitis: Pathogenesis and Treatment
Since the initial description of the free radical theory of aging, the implication has been reactive oxygen species (ROS) generated during normal and abnormal oxidative metabolism, drive the aging process. The exponential increase in intracellu
p66/Insulin like growth factor-1 Reno-Protection in diabetes
This supplement to an exisiting NIH-NIDDK R01 grant (DK-075533) is to accelerate the pace of research on the parent grant via enabling the hiring of a post-doctoral fellow for a period of two years.  Hiring a post-doctoral fellow will also fulf
Mechanisms of Glucocorticoid Action in Podocytes
Research Institute at Nationwide Children's Hospital
The project (ROI DK075718) is designed to evaluate the role of innate immunity in renal ischemia reperfusion injury and is focused primarily on the role of innate immune activation in acute kidney injury. Three aims were proposed in the origina
The Role of Inflammation in Ischemic Organ Injury
DESCRIPTION (provided by applicant): Despite recent advances in our knowledge of the neural, metabolic and genetic controls of food intake and body weight regulation, the causes of obesity remain elusive and compelling explanations about how ch
Food Cues, Calories, and Energy Regulation in Rats
Although Celiac Disease is a well understood form of gluten sensitivity, it can be ruled out in the cases of many gluten-sensitive individuals due to the absence of celiac-specific markers (most notably HLA-DQ2/DQ8 and villus atrophy). The path
NON-HUMAN PRIMATE MODEL OF GLUTEN-SENSITIVE ENTEROPATHY
The majority of the parent grant and its successful continuation rely on using confocal microscopy, which is essential for achieving the goals of the project. However, the manufacturer of the 9-year-old LSM 510 microscope, Carl Zeiss MicroImagi
Role of Na, K-ATPase beta isoforms in pump sorting and epithelial integrity
VA Greater Los Angeles Healthcare System
11301 Wilshire Blvd., Bldg. 113, Rm. 325B
The purpose of the award is to investigate potential changes in glycosaminoglycan sulfation in a podocyte-specific knockout of the glycosaminglycan processing enzyme, NDST1 (N-deactylase, N-sulfotransferase1).  Althought he effects of NDST1 kno
GLYCOSAMINOGLYCANS AND PODOCYTE BEHAVIOR IN THE RENAL GLOMERULUS
The underlying genetic factors that influence determinants of urinary SS, such as calcium excretion, are poorly defined. This project addresses these gaps in knowledge by identifying genetic associations with urinary lithogenic factors. To do s
Genetic determinants of urine lithogenicity
, create jobs, and stimulate economic development. The specific aim of this supplement is:  Synthesize dendrimers with varying surface charge but constant size.       Hiring personnel and purchasing an infra red spectrophotometer will enable us
A New Dimension in Renal Clearance Design Criteria for Dendrimer Nanostructures
Tubulointerstitial renal disease is an important component of the pathobiology of HIV-associated nephropathy (HIVAN), the most common cause of chronic renal failure in HIV-infected individuals. In HIVAN, HIV infection of renal tubular epithelia
THE ROLE OF FAT10 IN THE PATHOGENESIS OF HIV-ASSOCIATED NEPHROPATHY
This American Recovery and Reinvestment Act (ARRA) administrative supplement for RO1 DK079745-01 would be used primarily to support the salary of Courtney Rees, a Health Services PhD candidate, a very talented PhD predoctoral student who is int
The Increasing Kidney Disease Awareness Network (IKAN) Transplant Protect
therapeutic treatment. One such emerging treatment is the use of pharmacological chaperones, which are small molecules that are able to restore protein function by stabilizing a native protein conformation. While such an approach for AGT has g
Analysis of PH1-associated alanine:glyoxylate aminotranferase (AGT) using yeast
The destruction of renal tissue is associated with progressive tubulointerstitial fibrosis, which is a common final pathway in the development of end-stage renal disease. Renal fibrosis is associated with a reduction in tissue oxygen levels, wh
This project is a competing continuation of our project entitled 'Parallel Magnetic Resonance Imaging: New Techniques and Technologies,' which produced many of the key advances in highly accelerated parallel MRI, and demonstrated their use in r
Parallel Magnetic Resonance Imaging: New Techniques and Technologies
The objective of the proposed research is to develop a novel in vivo microscopic imaging technology, confocal photoacoustic microscopy (PAM). PAM can image intact biological tissues at high resolution with optical absorption contrast, which is
CONFOCAL PHOTACOUSTIC MICROSCOPY: TECHNOLOGY DEVELOPMENT
Critical sized bone defects caused by injury, disease or congenital malformations, remain a challenging problem in orthopedic medicine.  Current options to restore full function to such bone defects are limited due to slow rates of regeneration
The advent of ultrashort laser light pulses as a laboratory tool provides an opportunity to probe and manipulate anatomy and function in nervous systems. Ultrashort pulses are the essential means to drive the nonlinear absorption of light by bi
MANIPULATING NEURAL TISSUE WITH ULTRA-SHORT LASER PULSES
Activity #1 - summer intern -03S1: The goal of the summer project was to simulate and visually demonstrate impingement during the planning phase of the hip osteotomy procedure, include the interface as a simulation constraint when optimizing (m
COMPUTER-ASSISTED ORTHOPAEDIC SURGERY WITH INTRA-OPERATIVE BIOMECHANICAL GUIDANCE
Resorbable Calcium Phosphate Ceramics for Bone Graft Abstract Calcium phosphate (CaP) based ceramics are used in hard tissue engineering because of their excellent biocompatibility. There is a need for the development of biodegradable ceramic m
RESORBABLE CALCIUM PHOSPHATE CERAMICS FOR BONE GRAFT
This grant provided a summer research experience for one summer student in health-related scientific research.
Non-Invasive Localization of Vulnerable Plaques
Funds from this administrative supplement are being used to support senior postdoctoral fellow Rongmin Xia, as proposed in the supplement application.  Dr. Xia has been trained on the use of the ExAblate 2000 (Insightec, Inc.) to conduct and su
PULSED HIGH INTENSITY FOCUSED ULTRASOUND FACILITATED DRUG DELIVERY
This proposal is testing the hypothesis that adverse developmental outcomes in children are associated with exposure to methyl mercury (MeHg) from consumption of a diet high in fish. Since 1989, the Seychelles Child Development Study (SCDS) has
METHYL MERCURY EFFECTS ON ADOLESCENT DEVELOPMENT
using PKCs. bZip factor activity is subject to the identity of its dimeric partner. Phosphorylation of the ultimate target gene product, e.g., HO-1, alters its activity and turnover. In vitro and in cultured cells, we have discovered that: the
REGULATION OF HEME OXYGENASE-1 BY BILIVERDIN REDUCTASE
Parkinson Disease (PD) is a common neurodegenerative disease that affects over 1 million people in North America.  Although the cause of PD is unknown, environmental factors are suspected in the majority of cases.  Preliminary data from our lab
Ultraviolet (UV) irradiation from the sun is a well-recognized, otent environmental insult, and skin is directly exposed to UV irradiation. Long-term exposure to UV irradiation damages human skin connective tissue and promotes formation of skin
CYR61-A NOVEL POTENTIAL MEDIATOR OF PHOTOAGED HUMAN SKIN
Children are exposed to a mix of potential neurotoxicants, including metals, via widespread contamination of food, air, soil and, in some settings, water. Exposure to neurotoxicants during early development can be particularly deleterious. Furt
Metal and Organochlorine Exposure: Impact on Adolescent Behavior and Cognition
Ambient ozone is associated with increased respiratory illness, hospitalizations, and cardiovascular mortality. Because the lung is recurrently exposed to low level ozone, understanding how ozone modifies immune mechanisms is of considerable im
?Genetic models of retinal degeneration? The goals of the parent grant are to establish new retinal degeneration models to explore strategies for suppressing retinal cell death. To do so, we are using the fruit fly as an animal model, since man
Our long-term objective is to unravel the molecular genetics of hereditary human blinding diseases, such as retinitis pigmentosa (RP) and age-related macular degeneration (AMD). Genetic defects that lead to photoreceptor cell death in AMD and R
ARRA NOT-EY-09-002 NIH Administrative Supplement Request 2009 Molecular Studies of Retinal Degeneration in Drosophila
Based on our studies we developed the following hypothesis: In the eye, adenosine forms an intrinsic regulatory system that is essential for maintaining lOP within normal limits. Disruption of this system leads to elevated lOP, increasing the r
Adenosine Agonists: Potential Antiglaucoma Agents
EGR receptor signaling is a key element in triggering specific cell fate decisions in developing eyes.  But many of the downstream events and their finetuning in specific cell types is still poorly understood.  The dAcn protein may play a criti
Genetics of Endocytic Trafficking in Drosophila Eye - ARRA Stimulus Summer Student
The overall goal of this supplement is to accelerate our ability to understand how the brain uses visual information to generate reaching movements.  Reaching towards visual targets is critical for normal daily function, and is a good model sys
Decisions about where to look within a typical visual scene are governed by the relative salience of individual stimuli and current behavioral objectives. To date, the majority of studies examining the cognitive control of visual orienting have
Diencephalic Mechanisms of Visuomotor Integration
The overall goal of our research is to elucidate the role(s) of antimicrobial peptides such as defensins at the ocular surface.  These peptides are likely to particpate in direct antimircrobial killing, regulation of immune responses and wound
Adenovirus (Ad) mediated gene transfer is a promising technology for the treatment of many genetic disorders of the Central Nervous System (CNS). Many of the drawbacks that exist with first-generation Ad vectors have been resolved through the u
VP22 & TAT mediated gene theraphy for the CNS
, Grant U01 HG004728-01) where we will utilize the DNA from the identified cases and controls in the parent study.  We are in the process of conducting the nested case-control studies of NOS3 and NOS3 and environment interactions in relation to
In this supplemental proposal, we will describe the benefits of our recent advancements that will greatly enhance the studies in our original proposal by pursuing alternative approaches for the addition of chemistry to investigate the involveme
Subproject for Institution # 09-002183: Modulation of Signal Transduction by Nano-Topography
The objective of our project is to identify genotype-phenotype associations in individuals affected by hereditary optic nerve disorders through integrative systems-biology based approaches and the application of cost-efficient sequencing techno
Discovery of Biomarkers in Human Mitochondrial Diseases
The ability to coordinate head and eye movements for the retention of clear images on retina is fundamental for vision perception in daily life. Pathological changes to a region of Cerebellum, Flocculus, appear to cause severe deficits in our a
Neural Mechanisms of 3-D Linear Vestibulocular Reflex
The overall goal of the 3-years parent R01 grant, which ended Aug 31st, 2009 and currently in a first year unfunded extension , is a better understanding of the neural substrate of primate eye movements in depth, which require unequal rotations
NEURAL ORGANIZATION OF EYE MOVEMENTS IN DEPTH
This administrative supplement supports our experiments on finding novel cures for retinal disease and is allowing us to increase the pace of our research. The supplement is used to support the salary of a PhD-level scientist and to purchase ne
WNT SIGNALING AND NEUROPROTECTION IN THE RETINA
Photoreceptors are among the most metabolically active cells.  They have extraordinarily large mitochondria and consume oxygen at exceptional rates.  Energy production by glycolysis and oxidative phosphorylation must keep pace with energy consu
Myopia and glaucoma are highly prevalent ophthalmic disorders worldwide, and contribute significantly to ocular morbidity. There is substantial evidence that genetic factors play a significant role in the development of non-syndromic myopia and
International Collaborative Twin Study of Refractive and Glaucome Endophenotypes
Despite the great effort and resources that visual neuroscientists have dedicated to establishing a model for the organization of the human visual cortex,  information on the histological characteristics of cortical areas is very limited.  A we
A PROBABILISTIC MAP OF HUMAN VISUAL CORTICAL AREAS FROM QUANTITATIVE MICROSCOPY
Alzheimer's disease (AD) is the most common form of neurodegeneration however, adequate therapies do not exist to prevent or treat AD. Since 1999, Abeta immunotherapy has been shown to lower cerebral Abeta levels and improve cognition in AD mou
Mucosal Abeta Vaccination: Modulating the Immune Response
The long term objective of this grant proposal is to understand how the ribosome functions at the atomic level during protein synthesis. Our approach includes developing genetic and biochemical systems in the extreme thermophile Thermus thermop
POLYSOMES & SUBUNITS: STRUCTURE-FUNCTION RELATIONSHIPS
Polyamines are ubiquitous cellular components that play many roles in cellular physiology and in normal and neoplastic growth. There is good evidence that the polyamine biosynthetic pathway is a valid target for drug design. The planned experim
Use Solexa sequencing methods to analyze stepwise formation of genome changes.  We believe we can detect rare mutants in the population whose sequence is being determined. This should reveal new mutations even if they are unstable as predicted
Subproject for Institution # 008734: Genetic Analysis of Bacterial Chromosome Structure
Advances in computational biophysics depend on the development of accurate effective potentials and powerful sampling methods to traverse the rugged energy landscapes that govern protein folding, stability, and binding.  This supplement is focu
Computer Simulations of Protein Structure and Dynamics
Project Summary/Abstract How proteins fold, that is attain their three-dimensional structure, is a fundamental biological process with important implications for human health. Misfolded proteins are often toxic, as illustrated by the number of
Functional Diversity of J-protein Components of Hsp70 Chaperone Machinery
Drosophila's Dorsal Closure is a model system for cell sheet morphogenesis during development and wound healing. We plan to investigate the molecular, cellular, and emergent properties that drive morphogenesis during closure using biophysical (
MORPHOGENESIS: BIOPHYSICS AND GENETICS OF DORSAL CLOSURE
The long-term goal of this research is to understand the mechanisms eukaryotic cells use to regulate the assembly of cilia and flagella. The flagella of Chlamydomonas are maintained at a constant length, but mutations in four different genes: L
REGULATION OF FLAGELLAR ASSEMBLY IN CHLAMYDOMONAS
The goal of our research is to identify and characterize the machinery involved in eukaryotic DNA replication. We focus on the isolation of the individual proteins and protein complexes required for DNA synthesis and define their role in this c
The DNA of eukaryotic species is organized into chromatin, a highly condensed state implicated in key cellular functions and implicated in numerous diseases, including cancer. DNA compaction into chromatin is aided by specialized proteins calle
This research will examine how cells monitor the synthesis of rRNA, the essential component of protein synthesizing machinery, and regulates metabolism and other cellular activities.
Genetics and Biochemistry of Ribosome Synthesis
DESCRIPTION (provided by applicant): Plants have ancient classes of reproductive and vegetative actin genes with distinct expression patterns. During the last grant period we have examined the hypothesis that these ancient actin genes were pres
Differential Expression of the Diverse Plant Actins
University of Georgia Department of Genetics
The continuing development of synthesis strategies based on the chemistry of alkynyliodonium salts and their derived alkylidenecarbenes will occupy the majority of the proposed efforts. The alkynyliodonium salt-based chemistry will find purchas
ALKYNYLIODONIUM SALTS AND DERIVED DIYLS IN SYNTHESIS
Our long-term objectives are to define the pathway by which two haploid yeast cells fuse to become one diploid cell. Related to fertilization, conjugation is a fundamental process common to all sexually reproducing organisms. Conjugation also h
MECHANISMS OF NUCLEAR AND CELL FUSION IN YEAST
Point defects in the molybdenum-containing enzyme, sulfite oxidase (SO), can produce sever nenatal neurological symptoms that include dislocated ocular lenses, mental retardation, attenuated growth of the brand and early death.  This research w
This proposal is in response to Notice Number NOT-OD-09-058: NIH Announces the Availability of Recovery Act Funds for Competitive Revision Applications. The parent proposal sponsors the study of the structure and mechanism of the oxygen-bridged
METHANE MONOXYGENASE STRUCTURE AND FUNCTION
Clinical studies have demonstrated that the transfusion of packed red blood cells is independently associated with an increase in infectious complications, as well as mortality.  Basic investigation into the cause of this phenomenon is limited
Adhesion and migration are fundamental cell processes that are disrupted in disease states:in some cases, these disruptions cause or exacerbate the disease. Research has shown that there are many pathways and proteins involved in regulating adh
CELL SURFACE CONTROL OF CELLULAR PHYSIOLOGY
DESCRIPTION (provided by applicant): Specific gene expression is controlled by transcription factors binding to elements present in promoters and enhancers. In many instances multiple transcription factors can recognize the same DNA sequence, b
PROMOTER SPECIFICITY OF TRANSCRIPTION FACTORS
Our laboratory seeks to understand the control of messenger RNA decay in the gram-positive bacterium, Bacillus subtilis. While much is known about the mechanism and regulation of mRNA synthesis (transcription) and translation of mRNA into prote
INITIATION OF MRNA DECAY IN BACILLUS SUBTILIS
R01 funding has helped define the forces that drive transport and effect of endogenous signals and exogenously delivered compounds. The timing of this work could not be more critical. Drug-eluting stents (DES) present an innovative technology w
Nitric oxide synthase (NOS) is a family of enzymes that produces nitric oxide for use in regulating blood pressure, in immune system functioning, and in brain development, memory, and learning. Under pathological conditions, excess nitric oxide
Selective Inhibition of Neuronal Nitric Oxide Synthase
The broad research objective of the parent grant is to better understand tyrosine kinase signaling pathways activated in response to integrin-mediated cell-ECM adhesion, both in terms of biochemical mechanism and cell biological impact. The sup
FAK/Src/CAS Signaling in Cell Mobility and Invasion
The coupled transfer of electrons and protons transfer is fundamental in many areas of biology.  It is central to bioenergetics and the use of redox reactions to generate proton gradients.  It is key to the catalytic cycles of many metalloenzym
Understanding Coupled Transfers of Electrons and Protons Relevant to Biological Chemistry
Our research focuses on innate immunity in a model organism, the fruit fly Drosophila. By analyzing immune defenses across species representing diverse habitats, we hope to build a predictive model for innate immune gene expression. Such a mode
STRUCTURE AND FUNCTION OF DROSOPHILA NF-KAPPAB SIGNALING PATHWAYS
Defects in ciliary motility are now known to lead to a broad array of human genetic disorders. Dyneins are molecular motors required for the motile behavior of cilia and flagella. To understand how these organelles generate force, we need to de
MOLECULAR ANALYSIS OF FLAGELLAR DYNEIN FUNCTION
Centrosomes are the organelles at mitotic spindle poles that organize microtubules essential for chromosome segregation. Assembly of nascent centrosomes is a tightly regulated process that occurs exactly once each cell cycle. Defects in this pr
Role of MPSI Kinase and Yeast Spindle Pole Cycle
The proper assembly of the mitotic spindle is essential for the segregation of genetic material during cell division. Mis-regulation of this process contributes to developmental abnormalities and tumor progression. Recent work from our laborat
The incorporation of HIV-1 protease inhibitors (PIs) in 1996 into combination therapy regimens with two or more reverse transcriptase inhibitors has been critical to the reduction of AIDS related mortality, improvement of quality of life, and e
Design and Synthesis of nonpeptide Protease Inhibitors
Local regulation of the levels and activity of synaptic proteins is critical to plasticity. In this proposal, we investigate the role of translation in regulation of the levels of CaMKII and characterize the functional roles of the interaction
Neurochemistry and Genetics of Drosphila CaMKII
Compelling new evidence indicates that a small RNA-mediated gene silencing pathway protects archaea and bacteria against viruses and other mobile genetic elements.  This defense system, known as the CRISPR-Cas system or prokaryotic RNA interfer
Supplement for “Noncoding RNAs: From RNA Modification to Genome Defense”
DESCRIPTION (provided by applicant): A feature common to tumor cells is a high glycolytic rate. Increased glycolysis provides tumors with a selective growth advantage by supplying ATP to meet their high bioenergetic needs, and by supplying gluc
MODULATORS OF MAD FAMILY FUNCTION: MIX AND MSIN3A
Children with Cornelia de Lange syndrome (CdLS) display slow growth before and after birth, and are afflicted with mental retardation and defects in limbs and organs such as the heart. CdLS is caused by changes in genes that are also present in
An Animal Model for Cornelia de Lange Syndrome
DESCRIPTION (provided by applicant): Salmonella pathogens infect over a billion people each year worldwide resulting in 3 million deaths annually from septicemia, mostly in HIV-infected patients and 700,000 from typhoid fever (W.H.O. estimates)
COUPLING GENE EXPRESSION TO FLAGELLAR MORPHOGENESIS
DESCRIPTION (provided by applicant): Zinc is an essential nutrient because of the important roles this metal plays as a catalytic and structural cofactor. Several zinc-dependent proteins reside within organelles such as the endoplasmic reticulu
N-terminal domain of eukaryotic Kv channel, Kv4.2. Calcium-induced conformational change in KChIP/channel complex will be probed by a combination of x-ray crystallography and NMR spectroscopy methods. This study will expand our molecular under
Tertiary Structures of Potassium Channel Domains
The molecular mechanisms of gamete fusion remain poorly understood in most organisms.  Currently, Chlamydomonas is the only organism in which two proteins have been shown by gene disruption to be essential for the membrane fusion reaction.  Our
Gamete Membrane Adhesion and Fusion during Fertilization-ARRA Stimulus Admin Suppl
This is an extension of the studies supported by the parent grant. The main scope of the parent grant is to map the functional and physiological components of the inflammatory reflex.  Extensive work carried out under the parent grant demonstra
Macrophage Inactivation in Sepsis after Shock or Trauma
The supplementary work will lend biophysical insight into MMP activity and roles of exosites in elastase activity and in green tea inhibition of MMP-12. Postdoctoral staff will be retained, PhD students hired and trained, and useful equipment a
Matrix Metalloproteinase Inhibition and Specificity
This award is issued in response to Notice OD-09-060, Recovery Act Administrative Supplements Providing Summer Research Experiences for Students and Science Educators.PROJECT SUMMARY/ABSTRACTHedgehog (Hh) proteins are secreted morphogens that r
This supplement will be used to purchase equipment that will allow the PI to  delagate routine experiments  to a skilled laboratory technician. Also to re-hire a former laboratory technician for a part time position. These investments will allo
Structural Studies on Prokaryotic Potassium Channels
The objective of the proposed work is to understand how the Dmrt1 gene controls development and function of the testis. The testis has two essential functions: production of sperm, the cells that serve as vehicles for the immortality of male ge
This research will help us understand the role of calcium ions in the secretory pathway, defects in which are the basis of many human diseases.  This supplement would provide partial salary support for a post doc to work on specific Aims 2 and
Protein Interactions Controlling ER/Golgi Transport
The extracellular matrix (ECM) is critical for cellular decision-making through its role in tissue architecture and its stimulatory effects on cell growth, migration, and differentiation. Transmission of ECM signals is carried out by integrin r
EXTRACELLULAR MATRIX MODULATION OF CELL PHENOTYPE
Microtubule motor proteins are responsible for many aspects of intracellular transport and cytoplasmic dynein is a major minus end-directed motor in mammalian cells which orchestrates the movement of membranes, chromosomes and mitotic spindles.
Regulation of cytoplasmic dynein targeting
, reversible capture of ELP fusion proteins from solution on surfaces functionalized with ELPs.
During the previous funding cycle, we determined that a UAG-codon, located in the M. barkeri monomethylamine methyltransferase, encoded a new amino acid. Based on its electron density in the native and hydroxylamine complexes, we determined tha
(ARRA) L-Pyrrolysine chemical and structural biology
Eukaryotic cilia and flagella are ancient cellular appendages that have been adapted for motile and sensory functions.  Motile forms of these organelles are capable of propelling some cells like sperm and protozoa through a liquid environment w
INTRAFLAGELLAR TRANSPORT IN CHLAMYDOMONAS REINHARDTII
This is a revision application in response to the announcement NOT-OD-09-058: NIH Announces the Availability of Recovery Act Funds for Competitive Revision Applications This revision application proposes a set of studies to extend the specific
Translation initiation is a central biological process. It is also a key point in the regulation of gene expression. Eukaryotic translation initiation is a potential target of anticancer, antiviral and antifungal drugs. Attempts to develop drug
KINETIC DISSECTION OF EUKARYOTIC TRANSLATION INITIATION
Pre-mRNA splicing must occur with high fidelity to prevent catastrophic errors. Yet, the molecular mechanisms of fidelity in splicing are understood poorly. Splicing is catalyzed by the spliceosome, a dynamic ribonucleoprotein machine in which
MECHANISMS FOR REARRANGING RNA DURING PRE-MRNA SPLICING
The long-term goal of this project is to define the role of the novel lipid pathway mediated by sphingosine-1-phosphate (S1P) in inflammation and to establish components of this pathway as potential novel targets for anti-inflammatory therapy.
Sphingosine Phosphate Role In Inflammation
Telomeres are higher order nucleoprotein structures that physically cap the chromosome terminus and help to preserve genome integrity. In cells with unlimited proliferative capacity, including 95% of human cancers, telomeres are maintained by t
TELOMERE STRUCTURE AND FUNCTION IN ARABIDOPSIS
Integrin-mediated cell adhesion to extracellular matrices regulates the organization, maintenance and repair of numerous tissues, and abnormalities in adhesive interactions are often associated with pathological states. The adhesive process com
ARRA: FOCAL ADHESIONS IN CELL ADHESION STRENGTHENING
This administrative supplement requests additional equipment and personnel. One GRA will work on the structure determination of a large and exciting new protein, whose structure is unknown. This will provide a good test for our algorithms and a
Automated NMR Assignment and Protein Structure Determination
This is an equipment supplement to the parent grant whose overall objectives are to develop and apply new nuclear magnetic resonance (NMR) methods and web-based technology for the rapid and reliable collection, processing, and analysis of NMR s
Covariance-based NMR of Proteins and Complex Metabolite Mixtures
Our overall hypothesis is that PI4KII? (phosphatidylinositol 4 kinase II?), which produces more than 50% of the phosphatidylinositol 4 phosphate (PI4P) in the Golgi, regulates Golgi functions through its localized production of PI4P. The PI4P i
Phosphoinositide Regulation of Golgi-ARRA Stimulus Admin Suppl
The purpose of this work is to exploit our one-of-a-kind, high sensitivity flow and stopped-flow EPR to probe the real time folding and recognition of spin labeled biomolecules with a time resolution extending from 50 microseconds to seconds. T
ARRA Funded:  Supplement to Biomolecular Folding/Recognition Probed by Kinetic EPR (1038159/1/31733)
Our long-term goal in grant GM066859 (Bioinorganic Chemistry of Nickel: The Ureases and Nikr) is to understand protein structure, function and dynamics. Furthermore, the proposal is focused on understanding the fundamental aspects of bioinorgan
THE BIOINORGAINIC CHEMISTRY AND NICKEL: THE UREASES AND NIKR
This grant provided a supplement to by RO1, entitled !A model system to study the tumor suppressor APC!.  :  The supplement allowed us to retain two very talented senior postdocs, David Roberts and Nasser Rusan, who were key to advancing our IR
A model system to study the tumor suppressor APC
This research program focuses on the development of new synthetic strategies for the total synthesis of biologically active complex alkaloid natural products. Within each total synthesis goal lies the implicit aim of discovering and exploiting
SYNTHESIS OF BIOACTIVE COMPLEX ALKALOIDS
The process of DNA replication during S phase of the cell cycle is constantly challenged by the presence of damaged DNA on the replication template. Base lesions in chromosomes can cause DNA polymerase stalling, and if the stalled polymerase is
Replication checkpoint activation and silencing
DESCRIPTION (provided by applicant): Expression of the X-linked inhibitor of apoptosis (XIAP) is greatly enhanced in many classes of malignancy, and strategies to suppress XIAP function are showing great promise in the treatment of cancer. Alth
CONTROL OF APOPTOSIS AND SIGNALING BY XIAP
DESCRIPTION (provided by applicant): The long-term goal of this proposal is to understand the molecular and cellular mechanisms of signal termination mediated by the novel phosphatase PHLPP (PH domain Leucine-rich repeat Protein Phosphatase; pr
SIGNAL TERMINATION BY PHLPP, PH DOMAIN LEUCINE-RICH REPEAT PROTEIN PHOSPHATASE
The HOG pathway is a well-characterized mitogen-activated protein kinase (MAPK) cascade in yeast. MAPK pathways are evolutionary-conserved eukaryotic signaling modules that regulate diverse cellular processes including pheromone signaling, meta
MAPK Signaling in Single Yeast Cells: Dynamics, Variability, and Evolution
RNA acts as information carriers, catalysts, and regulators in essential biological processes, and understanding RNA structure and function is intimately linked to combating diseases. The long-term objectives of this project is to advance our u
Structure, Dynamics and Function of the Packaging RNA
The overall purpose of this grant is to enhance the communication cababilities of the Guadalupe County Sheriffs Office. This system to be purchased will be digital improving the audio quality and it will also be a trunked radio system increasin
Enhance services already offered by Drug Court
Uintah County Drug Court Enhancement Grant
Justice Assistance grant for law enforcement personnel and equipment.
Enhance outdated officer communication capabilities.
BJA FY 09 Edward Byrne Memorial Justice Assistance Grant Program Local Solicitation
OVW Recovery Act Tribal Domestic Violence and Sexual Assault Coalitions Program.  To help the 12 tribes of Michigan with resources and information to strenghten or estabilish domestic violence programs.
for Survivors of domestic violence and sexual assault.
AIAA Inc. Recovery Act Tribal Domestic Violence and sexual Assault Coalitions Program
MISSISSIPPI STATE COALITION AGAINST DOMESTIC VIOLENCE, INC.
The Mississippi Coalition Against Domestic Violence used Recovery Act funds to create the new position of Public Awareness Coordinator, to conduct 3 regional trainings for member shelters, and to conduct a statewide culminating institute as a f
OVW Recovery Act Grants to State Sexual Assault and Domestic Violence Coalitions Program
OVW Recovery Act statewide domestic violence coalitions provide direct support to member battered women's shelters and other domestic violence victim service providers through funding, training, technical assistance, public awareness activities
Technical Assistance and Technological Capacity Enhancement
NEVADA NETWORK AGAINST DOMESTIC VIOLENCE
Award funds will be used to implement the Nevada Economic Empowerment Project. This project will increase the safety of domestic violence survivors by expanding the financial knowledge they need in order to build a life free of violence. Funds
ARIZONA COALITION AGAINST DOMESTIC VIOLENCE INC
Recovery Act stimulus of the economy use of funds by the Arizona Coalition Against Domestic Violence Funds used to stimulate economy by employment of deputy director
DELAWARE COALITION AGAINST DOMESTIC VIOLENCE
Statewide domestic violence coalitions provide direct support to member organizations that offer domestic violence services through training, technical assistance, public awareness activities and systems advocacy efforts.  This award enables DC
Economic Recovery State Domestic Violence Coalition Grant
These federal funds may be used to provide funding to state agencies and local units of government, private not-for-profit organizations, law enforcement, and prosecutors that provide victim services programs to adult victims of domestic violen
Iowa's STOP Violence Against Women Formula Grant Program - Recovery Funds
The objective of the STOP (Services Training Officers Prosecutors) Violence Against Women Formula Grant Program is to support communities in their efforts to develop and strengthen law enforcement, prosecution, and court responses to violence a
Goal 1: To increase the ability of the Spirit Lake Nation to respond to domestic violence, dating violence, sexual assault and stalking committed against Indian women in the targeted service area. Objective 1: To provide annual training for tri
The Tulalip Tribes of Washington has been awarded $899,999.00 to renovate a tribal facility for use as the Legacy of Healing Advocacy Center and Safe House.  The funding will support the creation of five full-time jobs, including manager who wi
Legacy of Healing Victims of Crime Advocacy Center & Safe House
The Recovery Act Tribal Grants Program supports Tribes in their efforts to hire and retain criminal justice and victim services.
CSKT uses OVW Recovery Act funds to provide the necessary holistic services to victims of domestic/dating violence, sexual assault and stalking that will empower them to began a healthier life.  Funding under this project will help create the f
FAMILY SERVICES OF NORTHEAST WISCONSIN INC
Family Services of Northeast Wisconsin is providing transitional housing services for victims of domestic violence and sexual abuse in the greater Green Bay (Wisconsin) community. This project offers a collaborative effort between Golden House
Award is intended to support the transitional housing and the economic development process of our program participants, women survivors of domestic violence.
TITLE: Safe Homes Strong Communities: Transitional Housing and Supportive Services for Victims of Domestic Violence.  Safe Homes Strong Communities is a non-traditional community-based transitional housing project designed to minimize the disru
Safe Homes Strong Communities: Transitional Housing and Supportive Services for Victims of Domestic Violence
The award shall be used to provide comprehensive transitional housing services to victims and survivors of domestic violence, dating violence, sexual assault/rape and stalking in Frederick County, Maryland.Funds will be used to provide secure t
Heartly House OVW 2009 Recovery Act Holistic Transitional Housing Services for Victims of Domestic Violence and Sexual Assault
The Transitional Housing (Recovery) program continues to provide case management, rental and housing assistance for victims of domestic violence and sexual assault who are fleeing a domestic violence situation and need housing assistance. This
OVW Recovery Act Transtional Housing Assistance Grants
GIRLS EDUCATIONAL AND MENTORING SERVICES, INC.
Girls Educational and Mentoring Services (GEMS) is committed to ending commercial sexual exploitation and domestic trafficking of children by changing individual lives, transforming public perception, and revolutionizing the systems and policie
Transitional Services for Commercially Sexually Exploited and/or Domestically Trafficked Young Women
Housing Opportunity and Mentoring Enrichment II Project (HOME II) provides ten transitional housing apartment units for domestic violence, dating violence, stalking and sexual assault (relationship violence) survivors and their children in Lari
The Housing Opportunity and Mentoring Enrichment II (HOME II) Project
MONTGOMERY AREA FAMILY VIOLENCE PROGRAM, INC., THE
The project title is MAFVP Recovery Act Transitional Housing Assistance Program (OVW).  The MAFVP application for funding is under the Recovery Act Transitional Housing Assistance grant for Victims of Domestice Violence, Dating Violence , Stalk
Recovery Act Transitional Housing Assistance Program (OVW)
Guardian Angel Community Services Transitional Housing Program, Suzy's Caring Place, is a response to Guardian Angel's experience with victims fleeing abusive situations who reported limited choices for housing after staying in Guardian Angel's
Transitional Housing Program: Suzy's Caring Place
Through this project, Safe Harbor will provide an effective transitional housing program for domestic violence victims.
Recovery Act Transitional Housing Assistance Grants for Victims of Domestic Violence, Dating Violence, Stalking, or Sexual Assault
NEW HOPE CRISIS CENTER OF BOX ELDER COUNTY
Transitional housing for victims of domestic violence, dating violence, sexual assault and/or stalking with special emphasis to assist underserved populations
OVW Recovery Act Transitional Housing Assistance Grants for Victims of Domestic Violence, Dating Violence, Stalking, or Sexual Assault.
Community Against Domestic Violence (CADV)- Transitional Housing Project
To provide transitional housing assistance and related support services to minors, adults and their dependents who are homeless, or in need of transitional housing or other housing assistance as a result of fleeing a situation of docmestic viol
Child & Family Tennessee's THP project will provide holistic and victim-centered transitional housing that helps  victims of domestic violence, dating violence, stalking and sexual assault to move towards increased safety, permanent housing and
Transitional Housing Assistance Grants for Victims of Domestic Violence, Dating Violence, Stalking or Sexual Assault
WEST VIRGINIA FOUNDATION FOR RAPE INFORMATION AND SERVICES INC
The purpose of this program is to increase the capacity of the state sexual assault coalition in meeting the technical asssistance needs in the state to implement the newly created Sexual Assault Services Program as well as build the capacity f
Recovery Act STOP Violence Against Women Formula Grant Program - SASP Preparation and Services to Underserved Populations
OVW Recovery Act Grant to State Sexual Assault and Domestic Violence Programs
The purpose of this grant award is to create a new position, Training Coordinator, that will enhance the work of the Sexual Assault Network of Delaware. The Training Coordinator is responsible for the development and implementation of training
OVW Recovery Act Grants to State Sexual Assault and Domestic Violence Coalitions
WISCONSIN COALITION AGAINST SEXUAL ASSAULT INC
The Wisconsin Coalition Against Sexual Assault is requesting funds to support activities and projects aimed at building collaboration and coordination with state and local entities working to end sexual violence in Wisconsin.  Recovery Act Fund
Wisconsin Coalition Against Sexual Assault
NEW JERSEY COALITION AGAINST SEXUAL ASSAULT INC.
To develop and strengthen effective responses to sexual violence against women.
Sexual Violence Training and Data Collection System
NEBRASKA DOMESTIC VIOLENCE SEXUAL ASSAULT COALITION
The Nebraska Domestic Violence Sexual Assault Coalition will continue focusing its efforts on making primary prevention an important area of concentration for the state of Nebraska.  Through this program we will manage the Domestic Violence Pre
Recovery Act Grants to State Sexual Assault and Domestic Violence Coalitions Program
Prime Recipient will utilize funding from the Recovery Act State Coalitions grant program to promote economic recovery and stability in the local community and in the Coalition's infrastructure. By hiring and retaining new personnel- a part tim
Domestic Violence and Sexual Assault Act Training Coordination and Technical Assistance Project
The long term goal of this research program is to define the role of the Origin Recognition Complex (ORC) during the cell cycle in eukaryotes. ORC, a heteromeric six-subunit protein complex, is essential for DNA replication, however, its functi
THE ROLE OF ORIGIN RECOGNITION COMPLEX IN THE CELL CYCLE
. My R01 investigates the biochemical and cellular functions of mammalian formin proteins, which are potent actin assembly factors. Mammals possess 15 distinct formins, and cellular function is poorly understood for many of these isoforms. I fo
Comparative molecular physiology of mammalian formins
The purpose of this supplement is to obtain funding to purchase a high mass accuracy mass spectrometer to support work being done under the parent grant. The parent grant seeks to establish the targets and regulators of cullin-dependent ubiquit
Systematic analysis of proteolysis pathways for cullin targets
Members of the CLC family orchestrate the movements of chloride necessary for proper neuronal, muscular, cardiovascular, and epithelial function.  Although certain eukaryotic CLC channels have been well characterized functionally, we remain in
Mechanisms of CIC Chloride Transport Proteins
The long-term objective of this project is to learn more about how chromatin structure regulates transcriptional gene silencing in eukaryotes. The basic mechanisms used to generate inactive or silent chromatin are largely conserved in eukaryoti
ROLE OF CHROMATIN STRUCTURE IN REGULATING GENE SILENCING
The goal of the parent grant is to investigate protein-ligand and protein-protein interactions in HIV-1 reverse transcriptase (RT).  Being a key player in HIV infection, RT is the molecular target of the majority of AIDS drugs.  The biologicall
Subunit Assembly and Substrate Interactions in HIV-1 RT
Type IV pill (Tfp) are important determinants of bacterial virulence and biofilm formation which is the cause of many opportunistic and chronic bacterial infections. Tfp also mediate a form of bacterial surface motility known as social (S) glid
REGULATION AND MECHANISM OF M. XANTHUS SOCIAL GLIDING
The goal of this supplement is to rapidly  break new ground in chromosomal mechanisms and cellular function.  This supplement  has enabled us to purchase equipment to accelerate the rate of our research activities and has enabled us to perform
PcG Function of YY1 in Transcription and Development
The goal of the collaborative research proposed here is to establish a proof-of-principle that will provide foundations for the development of such technique(s).  The novelty of our approach is in the use of a laser beam to selectively activate
GENETICS OF LEG SIZE VARIATION IN INSECTS
Biophysical Optimization of Oligonucleotide Microarrays  High-quality, quantitative microarrays are an absolute requirement of array experiments involving comparative analysis of related genomes, or sensitive and specific diagnosis of infectiou
Biophysical Optimization of Oligonucleotide Microarrays
. To test this hypothesis we have set up a simple network consisting of camp and MAP-kinase 1, 2 pathways in neuronal cells. Using this network we will determine the role of the location, concentrations and activity state of key upstream stimul
WISTAR INSTITUTE OF ANATOMY & BIOLOGY (INC)
Wound and tissue injuries are common medical problems that often lead to excessive scar formation and subsequent loss of organ function without normal tissue replacement. Understanding the molecules that control scarless regenerative healing ca
The central objective of this project is to determine how RNA is recognized and cleaved by Dicer enzymes during induction of RNA interference. Three specific aims were proposed in the original application: 1) to compare the activities and speci
The proposed supplement will enable the continued work of a talented postdoctoral researcher, Dr. Stephane Roche, on a project which is related to but distinct from the parent proposal (Project 2: Biomimetic Synthesis of Rocaglamide Derivatives
BIOMIMETIC SYNTHESIS OF COMPLEX NATURAL PRODUCTS
As defined in the project abstract, the purpose of this proposal was to request supplemental funding for the purchase of critical scientific equipment to be used to accelerate the pace of research conducted under the IGR-approved scope of the p
Elucidating the Mechanisms of DNA Recombination
Centrosomes are microtubule-organizing centers (MTOCs) consisting of two centrioles surrounded by pericentriolar material. Accurate centrosome duplication precisely once per cell cycle is required for formation of a bipolar mitotic spindle, the
Ubiquitin-like modifications are similar to other macromolecular chemistry, such as transcription and DMArepair, in that they require multiple steps that are carried out by multi- protein complexes. Better understanding of how the multi-protein
THE ENZYMATIC PATHWAY OF A UBIQUITIN-LIKE MODIFICATION
Eukaryotic chromosomal replication is an intricate process that requires the coordinated and tightly regulated action of numerous molecular machines. Failure to ensure once only replication initiation per cell cycle can result in uncontrolled p
The Structural Basis of Eukaryotic Replication Origin Licensing by Cryo-EM
Many organisms show daily oscillations of various physiological and behavioral processes, which are generated by a genetically determined circadian clock system. It is believed that the circadian system has evolved to provide the most efficient
Molecular Mechanism of Circadian Transcriptional Control
G protein-coupled receptors (GPCRs) constitute a superfamily of cell surface receptors that regulate a variety of cell functions. The function of GPCRs is dictated by their intracellular trafficking and the positioning at the cell membrane. Ind
ER-TO-GOLGI TRAFFIC AND SIGNAL REGULATION OF GPCRS
The goal of this project is to take the advantages of the sialosides produced, the chemoenzymatic synthetic strategies designed, and the assay methods developed in the parent grant (R01GM076360, entitled Studies of naturally occurring structura
Subproject for Institution # 015327: Studies of naturally occurring structurally modified carbohydrates
Phosphorylation Dependent Recognition of a Histone mRNA Hairpin by SLBP (ARRA) Replication-dependent histone mRNAs express the bulk of histone proteins in mammalian cells.  Histone proteins are required for proper packaging of DNA into nucleoso
Phosphorylation Dependent Recognition of a Histone mRNA Hairpin by SLBP (ARRA)
experiments,we have found such approaches to be of limited utility in the isolation of ER-associated mRNPs. Thus, insights into mechanisms governing the partitioning of mRNAs to ER will require new methodologies. This challenge is the focus of
REGULATION OF MRNA PARTITIONING TO THE ENDOPLASMIC RETICULUM
The primary goal for this grant is to uncover the structural and functional bases for signaling through S-nitrosation.  Perhaps the most important target for these studies is the nitric oxide receptor, soluble guanylate cyclase (sGC), a hetrodi
Transport systems provide essential functions for all living cells. Their importance to medicine cannot be overemphasized as (1) they provide a basis for multidrug resistance in pathogenic bacteria, fungi and protozoans as well as in tumor cell
THE TRANSPORTER CLASSIFICATION DATABASE (TCDB)
The organization of the nucleus into distinct structural and functional domains is important for normal chromosomal processes like transcription and replication and disruption of this organization is known to lead to disease states like cancer
The objective of this research is to systematically study new genes in the Drosophila melanogaster subgroup and to investigate the tempo and mode of new gene originations. We will focus on the new chimerical genes created by RNA-involved retrop
DETECTION OF DISTRIBUTION OF NEW GENES IN DROSOPHILA PHYLOGENY
Amyloid deposition occurs in more than twenty different human diseases. This project is concerned with amyloid formation by Islet Amyloid Polypeptide (IAPP), the endocrine hormone responsible for pancreatic islet amyloid in type 2 diabetes. Isl
ARRA: Biophysical Studies of Amyloid Formation by Polypeptide Hormones
: A supplementary equipment grant for purchasing the ?AKTA-micro? machine from GE.  A small portion ($15,000-20,000) of the supplement will be used to purchase a 4 degree cooler to house the ?Micro? machine and a new set of chromatography colum
Molecular Mechanism of Small RNA-Induced RNA Silencing-ARRA Stimulus Admin Suppl.
Signal transduction is a fundamental process that enables cells to acquire information from the extracellular environment and respond to this information appropriately.  This awarded supplement will be used to focus on the establishment of new
Positive and Negative Regulation and RTK-Ras Signaling
Our long-term goal is to understand essential, conserved genes and mechanisms driving myoblast fusion. Our central hypothesis in our proposal is that specific cytoskeletal rearrangements are critical for all myoblast fusions. Our strong prelimi
The p90 Ribosomal S6 kinases (RSKs) are immediately downstream effectors of mitogen activated protein kinases and play a major role in regulation of cell proliferation and survival. Among the four isoforms, RSK4 is the most dissimilar and also
Interactions Between P90 Ribosomal S6 Kinase and Protein Kinase A
Structure-Function Studies of DNA Mismatch Repair A major focus of parent grant is to use atomic force microscopy (AFM) to characterize the conformations of the multiprotein-DNA complexes that govern the initiation of DNA mismatch repair.  AFM
Structure-Function Studies of DNA Mismatch Repair
This award focuses on the structural and functional characterization of antimicrobial natural products. The precise molecular details of how these agents fold and how they recognize their targets will be derived from high resolution X-ray cryst
Structural Studies of Target Recognition by Large Natural Product Antibiotics
How cell cycle events are controlled with growth remains an important and perhaps the most important, outstanding question in prokaryotic biology. A group of conserved and essential GTPase proteins, related to Ras, have been implicated in cell
Improved understanding of disease mechanisms and drug target identification requires better understanding of how diseases alter cellular processes from the healthy state. Our group has developed an integrative pathway search algorithm that reco
DEVELOP A DYNAMIC MODEL THAT INCOPORATES TEXT-MINING TO RECONSTRUCT NETWORKS
Perhaps one of the most influential concepts in protein mass spectrometry has been the notion of enzymatic protein digestion to render a collection of peptides of suitable size for conventional tandem mass spectrometry (collisional-activation,
ARRA SEQUENTIAL ION/ION REACTIONS FOR LARGE PEPTIDE AND WHOLE PROTEIN CHARACTERIZATION
Apoptosis is a program of cellular suicide that leads to the elimination of individual cells from the midst of a living tissue without damaging overall tissue architecture. Many stimuli, both extracellular and intracellular impact the cellular
Control of caspase activation in apoptosis
Findings from the Human Genome Project highlight the intricacy of interactions between cell regulation, genes and proteins. It is generally understood that biological functions and biological activities are controlled by subsets of genes intera
LOW-RANK APPROXIMATION TO PROBE-LEVEL DATA WITH APPLICATION TO EXON TILING ARRAYS
This award provides additional funding for 5R01GM081030-02 in the amount of $54,600.  The purpose of the funding is to purchase additional equipment that will accelerate the progress of the parent project.  Expected deliverables will include re
Tarteted Lanthanide Contrast Agents for in Cellulo Single molecule imaging
My RO1 grant (R01 GM081635; “Biochemical reconstitution of heterotrimeric G proteins in the Wnt pathway”) consists of two aims: 1) Which heterotrimeric G proteins participate in canonical Wnt signaling? 2) What are the mechanisms by which G
Biochemical Reconstitution of Heterotrimeric G Proteins in the Wnt Pathway
of the cell that allow it to respond appropriately to environmental stimuli. Many cancers and other diseases result from deranged gene regulation. We here propose an entirely new approach to studying the molecular mechanisms of gene regulation
Single-molecule visualization of transcription regulation mechanisms
We propose to determine the conformation of monomeric and dimeric arrestin2 in solution and the conformation of receptor-bound arrestin2 using multidimensional solution NMR methods. Using purified recombinant wild type (WT) arrestin2 expressed
Conformational Rebulation of Arrestin-Mediated Signaling
This supplement request involves molecular biology, protein purification and crystallization training for high school and undergraduate students plus one high school science teacher.  Participants will work under the guidance of university inve
INNOVATIVE METHODS FOR MEMBRANCE PROTEIN EXPRESSION AND CRYSTALLIZATION
Despite a great deal of research, a complete understanding of the actions of general anesthetics is still not available. The objective of this research is to advance our understanding of isoflurane, with the hope of gaining insights into all an
ISOFLURANE: IDENTIFICATION OF KEY NEW TARGETS
High density lipoprotein (HDL) and its major protein component apolipoprotein (apo) A-1 exert prominent anti-inflammatory and anti-oxidant effects.  Preliminary data presented in the parent application show that the apoA-1 mimetic peptide 4F, w
HDL MODULATION OF MONOCYTE FUNCTION IN ENDOTOXEMIA
The parent award, R01 GM083025 “Specificity of Effector Activation by Rho Family GTPases”, seeks to elucidate mechanisms regulating the activation of immediate downstream effectors of the Rho family GTPases Rac and Cdc42. Central to the pro
SPECIFICITY OF EFFECTOR ACTIVATION BY RHO FAMILY GTPASES
A precise understanding of the sequence-stability relationship is of fundamental interest in protein biochemistry, as protein instability is a cause of a wide range of pathologies, and it would enable facile engineering of proteins for industri
(ARRA) Combinatorial biophysics: Understanding protein stability with library approaches
DESCRIPTION (provided by applicant): Neural circuits are the functional and structural units of the nervous system. Defects in neural circuit function and development lead to a variety of neurological disorders. We are interested in understandi
A NOVEL NEUROIMAGING APPROACH TO MAPPING THE NEURAL CIRCUITS UNDERLYING BEHAVIOR
DESCRIPTION (provided by applicant): This proposal addresses novel mitochondrial-cytoplasm signaling pathways in Saccharomyces cerevisiae as a model eukaryote. In the first mitochondrial-cytoplasm pathway, we discovered a new paradigm in copper
Our study will provide new insights into the control and manipulation of the p53 pathway, perhaps the most important pathway protecting human cells against the development of cancer. These studies will give a deeper understanding of the biologi
Dynamics of Signaling Pathways: Mechanism and Function
The long term goal of the parental grant is to gain a better understanding and control over human embryonic stem cells (hESCs) by identifying and manipulating the key microRNAs required for hESC self-renewal and differentiation.  In the present
MicroRNA function in Human Embryonic Stem Cells
. Furthermore, we have used one of these molecules, Necrostatin-1, to demonstrate that necroptosis is an important component of acute pathologic injury in vivo in the case of ischemic brain and heart damage and endotoxic liver destruction. Disc
Mechanistic Analysis of Necrostatins: Specific Inhibitors of Programmed Necrosis
Developing an understanding of the molecular mechanisms that underlie learning and memory stands as one of the central challenges of modern science. Our proposed studies will focus on a carbohydrate modification that plays a central role in thi
ROLE OF FUCOSYL SACCHARIDES AND O-GLCNAC GLYCOSYLATION IN NEURONAL COMMUNICATION
This administrative supplement will support three additional researchers for 10-12 weeks during the summer months of 2009 and 2010. In 2009 we will hire two undergraduates and another science educator.  They will be trained in beetle husbandry
This grant is a supplement to the Sensory Experiences Project (R01-HD42168) to expand existing aims and accelerate scientific discoveries surrounding the heterogeneity, development and functional impact of sensory features in children with ASD.
Sensory Experiences in Children with Autism-ARRA
Over the last 4 years the parent grant (HD 44517) has been focused on improving our understanding of the pathophysiology of anesthesia-induced developmental neurodegeneration so that effective neuroprotective strategies can be developed. Our wo
Identification of All Functional Elements in Selected Model Organism Genomics
A Systematic RNAI-Based Map of C. elegans Embryogenesis
To involve undergraduate students with potential interests in research careers in summer research and to train them for the workforce.   It also would offer the opportunity for additional training and refreshment of science interests on the par
The Kiss1 gene codes for a family of peptides called kisspeptins, which bind to a G protein-coupled receptor known as Kiss1r (also known as GPR54). Kisspeptin signaling through Kiss1r is essential for normal reproductive development and fertili
Kisspeptin/GPR54 in the Female Neuroendocrine Axis
Two additional age and sex matched comparison groups will be recruited? girls with mosaic (45X, 46XX) TS genotypes and Williams syndrome (WS).  As girls with mosaic TS genotypes may have less severe cognitive problems relative to girls with TS
Gene, Brain and Behavior in Turner Syndrome
DESCRIPTION (provided by applicant): Religious congregations reach many lives and play an important role in working for social change. Could they play a similarly powerful role in the fight against HIV/AIDS? Although there is some evidence for
URBAN CONGREGATIONS' CAPACITY FOR HIV PREVENTION & CARE
Brain development in the first two years of life is the most dynamic and perhaps the most important phase of postnatal brain development.  In this time period there is a significant increase in overall brain size, with the brain reaching over 8
Early Brain Development in One and Two Year Olds -ARRA Funds
) can create a crisis for the newborn's family and healthcare professionals. Decisions about gender assignment, genital surgeries, and strategies to minimize stigma often are made quickly and under pressure. Clinical management of patients with
QUALITY OF LIFE IN INTERSEXUALITY: A PEDIATRIC CLINICAL AND RESEARCH TOOL
The Prenatal Cytogenetic Diagnosis by Array-Based Copy Number Analysis (aCNA) administrative supplement has goals consistent with ARRA funding guidelines.  The supplement will: 1) create new geographically dispersed jobs for the entire 2 year p
Prenatal Cytogenetic Diagnosis by Array-based copy number Analysis
Project Summary Stroke is the leading cause of long-term disability in the United States. Approximately 70-88% of persons with stroke have some degree of motor impairment. A major goal of research in stroke rehabilitation is to harness the abil
Sensory-driven motor recovery in poorly recovered subacute stroke patients
Preterm birth is a major public-health issue because of its increasing incidence combined with the frequent occurrence of subsequent behavioral, neurological, and psychiatric challenges faced by surviving infants. Resting state fcMRI is an idea
UNDERSTANDING NEUROBEHAVIORAL DEFICITS IN PRETERM INFANTS THROUGH IMAGING
DESCRIPTION (provided by applicant): The prevalence of overweight and obesity among children and adolescents has been increasing dramatically with low-income and some racial/ethnic minority populations being at highest risk. Rising obesity rate
EXCESS BMI GAIN DURING ELEMENTARY SCHOOL: THE ROLE OF CONTEXTUAL FACTORS
This application is a revised submission for a 5-year competitive continuation to grant 1R01-DA015269, Gender Identity and HIV Risk. The long-range goal of our research is to reduce HIV transmission among individuals stigmatized for their gende
We have established a powerful discovery strategy to determine critical gene function and to identify and prioritize candidate downstream genes.  Our strategy comprises morpholino oligonucleotide (MO)-mediated, specific gene knockdown, validati
Novel Roles of Pluripotency Regulators in the Early Mouse Embryo
This Supplement to Parent Grant 1R01HD058567; ?N-carbamylglutamate in the treatment of hyperammonemia? (PI Mendel Tuchman M.D.) was requested to provide employment opportunities for a undergraduate college student who is seeking to increase his
N-carbamylglutamate in the treatment of hyperammonemia
we will conduct a survey of New Orleans residents displaced by Hurricane Katrina, analyze the results, and disseminate the data. The specific aims of the project are to field the Displaced New Orleans Residents Study (DNORS); to analyze the re
SURVEY OF NEW ORLEANS RESIDENTS DISPLACED BY HURRICANE KATRINA
The approved summer student project seeks to investigate the role of TGF-ß in intestinal macrophage differentiation in transgenic mice that lack TGF-ß signaling. We had designed a set of sequential studies to investigate the hypothesis that t
ROLE OF TRANSFORMING GROWTH FACTOR-BETA IN NEONATAL NECROTIZING ENTEROCOLITIS
Community Partnerships for Child Safety: This project aims to prevent Injuries to Children in Baltimore City by building on ongoing community work: a) Johns Hopkins CARES (Children ARE Safe) mobile resource center; b) Baltimore City Fire Depart
KANSAS COALITTION AGAINST SEXUAL AND DOMESTIC VIOLENCE
This award will support training activities and public awareness media development to enhance the capacity of sexual assault advocacy programs to respond effectively to victims and survivors of sexual assault and enhance the response of the cou
Enhancing Advocate and Court Response to Victims of Domestic and Sexual Violence Through Training, Media, and Long-Term Planning
MICHIGAN COALITION AGAINST DOMESTIC AND SEXUAL VIOLENCE
MCADSV Recovery Act funding stimulates the economy by supporting the retention of two critical technical assistance positions to coordinate state victim services activities and collaborate and coordinate with Federal, State, and local entities
MCADSV Technical Assistance and Training
2009 BYRNE JUSTICE ASSISTANCE GRANT (JAG) PROGRAM AWARD- AMERICAN RECOVERY AND REINVESTMENT ACT OF 2009
The Award that was given, was funds that we used to purchase two Ford Escape Vehicles, that were fully stocked with Crime Scene Equipment, that is used to respond to Crime Scenes.  All supplies were purchased with Stimulus Funds.
Austell Crime Scene Investigation Stimulus Recovery
ARRA Supplemental Funding for the Child Care and development fund to provide child care financial assistance to low-income working families and fund activities to improve the quality of child care.
The $5,000,000 ARRA funds were distributed, in the same manner as regular Community Services Block Grant (CSBG) funding, in the following spending categories of service: Education; Emergency Services; Employment; Health; Housing; Income Managem
ARRA Supplemental funding for the Child Care and Development fund (CCDF); The CCDF ARRA Funds will be used to provide child care financial assistance to low-income working families and fund the following activities:  parenting classes, parent/P
ARRA Supplemental Funding for the Child Care and Development Fund.  The CCDF funds will be used to improve overall child care program quality, efficiency and safety.
CCDF Arra funds have been used to provide child care financial assistance to low-income working families and fund activities to improve the quality of child care.
Provide child care financial assistance to low-income working families and fund activities to improve the quality of child care.
White Earth Reservation Child Care Program expects to utilize the ARRA funds to help communities, children and families in creating and developing high quality child care services in their community; by investing in the economic development by
To be used to hire one full time officer
Administrative funds associated with the cost of storing, handling and distributing federal food commodities.
Emergency Food Assistance Program (Administrative Costs)
GRAND PORTAGE RESERVATION TRIBAL COUNCIL
TRUCK PURCHASE: Pick-up donated food from distribution agency and local delivery of donated food to elderly and those without transportation.  The Truck reduces travel expense giving back to the program, thanks much appreciated.
Food Distribution Program on Indian Reservations
American Recovery and Reivestment Act Port Security Grant Program (ARRA PSGP)
Port of Palm Beach Communications Project
Petty Island Terminal Security Enhancement
American Recovery and Reinvestment Act Port Security Grant.
American Recovery and Reinvestmant Act Port Security Grant Program (ARRA PSGP)
American Recovery & Reinvestment Act Port Security Grant Program
All Other Basic Organic Chemical Manufacturing
Invest in public transportation by renovating and improving the ferry service terminal building.
Security Improvements to Culebra-Vieques Ferry Service in the Fajardo Region
ARRA Port Security Grant Program - New Bedford Pier Security
American  Recovery and Reinvestment Act Port Security Program (ARRA PSGP)
American Recovery and Reinverstment Act Port Securtity Grant Program (ARRA PSGP)
American Recovery and Reinvestment Act Rail and Transit Security Grant Program - Law Enforcement
American Recovery and Reinvestment Act Rail and Transit Security Grant Program-Capital Projects
American Recovery and Reinvestment Act Rail and Transit Security Grant Program Capital Projects (ARRA TSGP - CP)
COPS Hiring Recovery Program/ Sworn Police Officers
The overall purpose of the funds is to hire 50 new Police Officers who will uphold the laws of the City of Los Angeles, County of Los Angeles, State of California and the Federal Government. The expected outcome is the increased health, welfare
ARRA - Cmnty Policing Enhance Hiring Prgm - 2009
To fund 18 full time officers, all 18 officers will be new hires.
Cops Hiring Recovery Program (CHRP) for the Santa Ana Police Department
City of Santa Ana / Santa Ana Police Department
The COPS Hiring Recovery Program (CHRP) provides funding directly to law enforcement agencies to hire and/or rehire career law enforcement officers in an effort to create and preserve jobs, and to increaase their community policing capacity and
The COPS Hiring Recovery Program award will provide federal funds over a three-year grant period towards the salaries and fringe benefits of up to 50 officers. The City must retain the funded positions for at least one year after the grant ends
The COPS Hiring Recovery Program (CHRP) provides funding directly to law enforcement agencies to hire and/or rehire career law enforcement officers in an effort to create and preserve jobs, and to increase their community policing and crime pre
The Cops Hiring Recovery Program (CHRP)provides funding directly to law enforcement agencies to hire and or rehire career law enforcement officers in an effort to create and preserve jobs, and to increase their communty policing capacity and cr
The COPS Hiring Recovery Program provides funding directly to law enforcement agencies to hire and/or rehire career law enforcement
The Cops Hiring Recovery Program (CHRP) provides funding directly to law enforcement agencies to hire and/or rehire career law enforcement officers in an effort to create and preserve jobs, and to increase their community polcing capacity and c
The COPS Hiring Recovery Program (CHRP) provides funding directly to enforcement agencies to hire/rehire career law enforcement officers in an effort to create and preserve jobs and to increase their community policing capacity and crime preven
To hire a police officer to protect the city .  To patrol community, issue citations and provide protection for the city
The COPS Hiring Recovery Program (CHRP) provides funding directly to law enforcement agencies to hire and/or rehire career law enforcment officers in an effort to create and preserve jobs, and to increase their community policing capacity and c
The COPS Hiring Recovery Program (CHRP) provides funding directly to law enforcement agencies to hire and / or rehire career law enforcement officers in an effort to create and preserve jobs, and to increase their community policing capacity an
The COPS Hiring Recovery Program (CHRP) provides funding directly to law enforcement agencies to hire and/or rehire career law enforcement officers in an effort to preserve jobs, and to increase their community policing capacity ad crime preven
The COPS Hiring Recovery Program (CHRP) provides funding directly to law enforcemetn agencies to hire and/or rehire career law enforcement officers in an effort to create and preserve jobs, and to increase their community policing capacity and
The COPS Hiring Recovery Program (CHRP) provides funding directly to law enforcement agencies to hire and/ or rehire career law enforcement officers in an effort to create and preserve jobs, and to increase thier community policing capacity and
The award was intended to provide supplemental funds to support a pre-dent undergraduate or prematriculating dental student for a summer research experience. The student was to participate in an ongoing research project supported by our parent
Molecular Basis of Blood Coagulation Regulation
A key component of the parent grant that this supplement supports is the measurement of phospholipase and triglyceride lipase activities in plasma from a variety of mouse models and human subjects. Using a systematic approach, we will use these
HDL metabolism: Influence of extracellular lipases
The overall purposes of this administrative supplemental grant are (1) to increase the number of minority biomedical and behavioral scientists, and (2) to successfully accomplish the proposed experiments in the parent grant application.  In the
Mechanisms for Hypoxic Ca2+ Release in Pulmonary Artery Myoctes
Saphenous vein, mammary artery, and radial artery are all used as conduits for bypassing coronary artery stenoses. The focus in our laboratory is to develop methods to prevent vein graft failure. The current RO-1 proposal, ?Prevention of Vein G
The broad and long-term objective of this research project is to test the hypothesis that simultaneous sympathovagal discharges are the immediate triggers of paroxysmal atrial fibrillation (PAF) and that severing the connection between the auto
Autonomic Nerve Activity and Paroxysmal Atrial Fibrillation
Abnormal vascular smooth muscle cell (SMC) growth and migration contributes to hypertension, atherosclerosis, and restenosis. SMC function is controlled by complex regulatory mechanisms, which are governed in part by interactions with the extra
We previously reported that plasma testosterone levels are two-fold greater in hypertensive adult male IUGR offspring relative to normotensive adult male control offspring.  More importantly, castration abolishes hypertension in adult male IU
Low Birth Weight, the Kidney, and Hypertension
Visceral sensory pathways that innervate the cardiovascular, respiratory and gastrointestinal systems are critical for reflex control of autonomic homeostasis. It is well established that functional characteristics of visceral reflexes, includi
NEUROTROPHINS AND DEVELOPMENT OF BARORECEPTOR PATHWAYS
, involve lung cell apoptosis, oxidative stress, and matrix proteolysis. In Specific Aim (SA) #1 we will investigate whether ceramide upregulation is necessary and sufficient to trigger emphysema. We will utilize the VEGFR-inh model and inhibit
Ceramide-induced lung destruction in emphysema
Title: Support for postdoctoral fellow Dr. Zongtian Tong. Award provides funds for salary and supplies to support a postdoctoral research fellow, Zongtian Tong. Dr. Tong&apos;s project will advance our understanding of the regulation of SREBP t
REGULATION OF CELLULAR CHOLESTEROL HOMEOSTASIS
Hematopoiesis has been extensively studied in many animal models, including mouse embryonic stem (ES) cells and murine embryos. However, analyses of human hematopoietic development typically utilize blood cells isolated from bone marrow or umbi
Hematopoietic Precursor Development from Human ES Cells
This administrative supplement was used to hire a full-time employee (FTE) to assist NIH-RO1 funded principal investigator (PI). The research goals proposed for the new FTE was within the research scope of the parent grant at the level of the s
Regulation of Wnt Signaling by Pap2b during Angiogenesis
This grant provided a summer research experience for two undergraduate research assistants in health-related scientific research.
THE EFFECTS OF PERCEIVED DISCRIMINATION ON MENTAL AND PHYSICAL HEALTH
Our goal for this supplement during the two years of ARRA support is to achieve two research objectives closely related to and within the scope of the parent grant entitled, Shwachman-Diamond Syndrome: Molecular Pathogenesis.    Shwachman-Diamo
Transplantation-associated arteriosclerosis (TAA) is the major cause of death in recipients who survive more than one year after cardiac transplantation. TAA is characterized by infiltration of inflammatory cells followed by the formation of a
KLF4, TGF-beta 1, and transplantation arteriosclerosis
Self-renewal is the process by which at least one daughter cell retains the full developmental potential of its predecessor when stem cell division takes place. It is critically important for maintaining lifelong function of the blood forming (
I am requesting an administrative supplement for an NIH-funded application (HL081395) under the auspices of the American Recovery and Reinvestment Act of 2009 (NOT-OD-056). The goals of this administrative supplement are to accelerate the pace
Caveolae and Anesthetic Induced Cardiac Protection. The series of experiments proposed in the ARRA supplement request will determine a novel role for Cav-3 expression in delayed preconditioning. Cav-3 may serve as a novel therapeutic target for
Caveolae and Anesthetic Induced Cardiac Protection
Abdominal aortic aneurysms (AAAs) comprise the 10th leading cause of death in Caucasian males 65-74 years of age and accounted for nearly 16,000 deaths overall in the year 2000. Understanding the pathophysiology of AAAs is an important undertak
Gender Differences in Experimental Aortic Aneurysms
Production of reactive oxygen species (ROS) and changes in the cellular redox environment regulate various aspects of cellular function.  Previous studies of oxidative stress in vascular disease have focused on ROS generating systems.  Little i
Glutathione Peroxidase & Redox State in Atherosclerosis
Disorders of lipid metabolism are responsible for several important established risk factors for cardiovascular disease, which continues to be the leading cause of morbidity and mortality in the United States. Despite of decades of research, ma
ARRA: Role of Proprotein Convertases in Lipoprotein Metabolism
Fibroblasts mediate the abnormal tissue repair characteristic of fibrosis, but their origin in fibrotic lung remains unclear. Many of the fibrogenic characteristics of lung fibroblasts are regulated by expression of Thy-1, an outer membrane lea
REGULATION OF FIBROBLAST PHENOTYPE IN LUNG FIBROSIS ARRA SUPPLEMENTAL FUNDS
Ras proteins are crucial regulators of cell proliferation, survival and differentiation. Aberrant activation of Ras proteins, either by Ras mutations or by altering genes that directly or indirectly regulate Ras, is common in both solid tumors
Award rescinded by NIH due to investigator transfer.  Principal investigator, Gary Wright, transferred from the Medical University of South Carolina to East Tennessee State University.  Award revised to reflect a 1 day project period with $0.00
Role of Prolyl Hydorxylase Oxygen-Sensor in Cardioprotection
Disturbances in mineral metabolism are highly prevalent among older adults and may adversely impact cardiovascular health. In our NHLBI funded application, 'Mineral Metabolism and Cardiovascular Risk Among Older Adults (5R01HL084443-03),' we ad
MINERAL METABOLISM AND CARDIOVASCULAR RISK AMONG OLDER ADULTS
Neutrophils are the most abundant cell type among circulating white blood cells and constitute the first line of host defense against invading bacteria and other pathogens. They are terminally differentiated cells and normally have a very short
Molecular basis of neutrophil spontaneous death
Individuals live within a series of hierarchical environments, and these environments are associated with health and behaviors over and beyond individual level influences such as socioeconomic status or race. In many cases, these macro-level en
CARDIOVASCULAR HEALTH OF SENIORS AND THE BUILT ENVIRONMENT
Superoxide plays an important pathophysiological role in the development of hypertension.  Oxidative stress has been demonstrated in patients with essential hypertension, renovascular hypertension, malignant hypertension and preeclampsia, as we
Regulation of Superoxide Production by the Macula Densa during TGF
THE ROLE OF FLUID FLOW IN VALVULOGENESIS Early cardiac cushions are located in the atrioventricular canal (AV) of the embryonic heart. These cushions are populated with mesenchymal cells and are the primordia for the cardiac valves and membrano
THE ROLE OF FLUID FLOW IN VALVULOGENESIS
A Ph.D. Candidate will work on the project to minimize delays in the project and will include, basic lab supplies, experiment reagents, and a data analysis workstation.
The long-term goal of this research is to develop methods for time resolved, low dose cardiac CT imaging. Specifically, we will develop algorithms that estimate the time-dependent motion vector field of the heart from the measured data and inte
TIME RESOLVED CARDIAC COMPUTED TOMOGRAPHY WITH PATIENT DOSE REDUCTION
Despite the origin of pulmonary arterial hypertension (PAH), pulmonary vascular resistance rises due to pulmonary vasoconstriction, arterial remodeling and polycythemia leading to right heart failure and death. Rodents exposed to chronic hypoba
NFATc3 IN CHRONIC HYPOXIA PULMONARY HYPERTENSION
Development of effective cell based therapies to mediate wound and cardiac regeneration is a national priority and has been identified as two Challenge Areas (11-GM-101 and 11-HL-101). Our funded R01 proposal addresses these challenge areas as
Creating Super Stem Cells for Cardian And Wound Repair
An intact alveolar epithelial barrier is required for recovery from acute lung injury and ARDS, but the mechanisms for regulation of the alveolar barrier are not fully understood. Previous work in our laboratory has shown that the tight junctio
Regulation of alveolar barrier function by claudins
This proposal seeks an administrative supplement to support the hiring of an additional study coordinator to enhance patient recruitment, collection of DNA, Plasma, and genotyping of patients in the Penn Heart Failure Study.  This will allow us
Genomics of Myocardial Transcription Factors in Cardiac Remodeling
Neurotrophins affect airway smooth muscle tone. Air flows into the lungs through the conducting airways (trachea and bronchi) and, with every breath we take, the airways rhythmically contract and relax with each breath; this change in airway sm
Neurotrophin Regulation of the Airway Pa
The main focus of this study is to characterize the cellular mechanisms underlying functional hyperemia in the cerebral cortex. Functional hyperemia occurs as a function of the communication between neurons, astrocytes and the cerebral microcir
SIGNALS AND TARGETS UNDERLYING MECHANISMS FOR NEUROVASCULAR COUPLING IN THE BRAIN
The purpose of this grant is to develop a mouse model of pacing-induced chronic AF to elucidate the contribution of calcium channels in chronic atrial fibrillation.  Atrial fibrillation (AF) is the most common cardiac arrhythmia affecting about
CaMKII Regulation of Cardiac Ryanodine Receptors in Atrial Fibrillation
These studies will lead to a more comprehensive understanding of how EpoR signals through JAK2 to regulate erythropoiesis, and how JAK2 mutations contribute to myeloproliferative disorders and lukemia.
Erythropoietin Receptor Signaling in Erythropoiesis - ARRA Stimulus Admin Suppl
Diseases of the lung contribute to at least four of the top ten causes of death worldwide. In the United States alone, it is estimated that 11 million people are diagnosed with chronic obstructive lung disease and 24 million people have evidenc
In Vivo and In Vitro Characterization of Bronchio-Alveolar Stem Cells
Supplemental salary and equipment funds will be used to accelerate Aim 1 (of parent grant). The goal is to define the molecular mechanisms involved in inhibition of platelet activation and aggregation, which will contribute to a better understa
Negative regulation of platelet activity
This is an administrative supplement to an active R01 grant (1 R01 HL090975-01) funded by the NHLBI. The parent grant investigates the role of adiposity on vascular inflammation, immune cell activation, and neuroendocrine responses in 200 prehy
ROLE OF OBESITY ON VASCULAR INFLAMMATION AND IMMUNE CELL ACTIVATION IN PREHYPERTE  Awardee Organization: UNIVERSITY OF CALIFORNIA SAN DIEGO
Ion channels are pore-forming proteins that are present in the membranes of all cells. Ion channels control the flow of ions (and therefore electrical current) across the membrane of cells. The movement of ions across the cell membrane results
These experiments will conclusively demonstrate or refute the importance of corin activity to the autocrine paracrine anti hypertrophic actions of the endogenous NPS, and provide biological confirmation for our previous genetic association stud
Genetic Determinants of Hypertensive Heart Disease in CRI
The luminal diameter of muscular arteries and arterioles of the microcirculation is the principal site of control of vascular resistance. These small blood vessels are significant regulators of blood pressure and local blood flow distribution,
TRP Channel-Dependent Regulation of Arterial Tone
During hematopoiesis, the lineage-specific transcription programs are accompanied and maintained by appropriate patterns of active or repressive histone modifications. Epigenetic mechanisms play an important role in controlling stem cell poten
Regulation of Insulator Function and Globin Gene Expression by USF and Associated?
Early embryonic blood vessels form with great anatomical reproducibility to ensure homeostasis and survival. How the vasculature acquires its stereotypical architecture is poorly understood. To uncover the genetic and cellular basis of vascular
Molecular and cellular mechanisms of vascular by PlexinD1 signaling
Pseudomonas aeruginosa is an important cause of serious infections in humans with a predilection for lung infections in the form of either acute pneumonia in hospitalized patients (usually associated with mechanical ventilation) or chronic pneu
Mechanisms of adaptive immunity to P. aeruginosa in the Lung
The long term goal of this study is to understand how biological membranes control their structural integrity, dynamical response, and physiological performance. Here we specifically study the erythrocyte membrane which has a protein network co
3D DYNAMICS OF PROTEIN NETWORK COUPLED TO LIPID BILAYER IN DISEASED ERYTHOCYTES
The parent grant originally planned to perform brain microdialysis experiments in collaboration with the Neurosciences Center at LSUHSC in New Orleans and therefore this equipment and the associated supplies were not budgeted in the application
BRAIN-TARGETED ACE2 OVER-EXPRESSION ON ANGIOTENSIN-II-MEDIATED HYPERTENSION
This supplemental request is focused on providing financial support for an additional post-doctoral fellow to accelerate the rate of scientific progress of the funded parent grant research. This 2 year supplement is requesting salary and resear
THE ROLE OF PLATELETS IN ALLOANTIBODY MEDIATED TRANSPLANT REJECTION
Transposase activity was thought to be extinct in humans because DNA movement can be deleterious in higher organisms, resulting in genomic instability and perhaps malignancy. We isolated a human transposase protein termed Metnase that had prefe
TRANSPOSASE PROTEIN METNASE IN LEUKEMIC DECATENATION
Innovative interdisciplinary work is essential to address the most challenging issues in the era of genomic biomedical research. One of these is the evolutionary structure/function of transcriptional regulation. Comparative molecular evolutiona
Comparative Bioinformatics and TP53 Expression
G-protein coupled receptors (GPCRs) are involved in various cellular signaling processes and activated by a diverse array of ligands. Many major diseases involve in malfunction of these receptors. Therefore, they are among the most important dr
EFFICIENT AND SENSITIVE MINING SYSTEM FOR G-PROTEIN COUPLED RECEPTORS
Inadequate recruitment of eligible subjects for clinical trials is a major impediment to the advancement of medicine. Use of an EHR-based, point-of-care Clinical Trial Alert (CTA) approach has been shown to significantly improve recruitment in
Evaluating EHR-Based, Point of Care, Trial Recruitment Across Clinical Settings
This award is issued in response to Notice OD-09-060, Recovery Act Administrative Supplements Providing Summer Research Experiences for Students and Science Educators.  DESCRIPTION (provided by applicant): Selective manipulation of the function
NOVEL NEURONAL NACHR-TARGETED PEPTIDES-ARRA SUMMER SUPPLEMENT
Child Attention Deficit Hyperactivity Disorder (ADHD) represents a significant public health concern because it is common, costly, impairing, and chronic, placing children at substantial long-term risk. Since genetic and contextual factors are
Genetics of ADHD: Haplotype and Endophenotype Approaches
The long term goal of research in this lab is to understand how sensory experience during critical periods of development, mediated by the activity-driven functioning of circuits in the CNS, is translated into lasting structural change in synap
Synapse Remodeling and Neuronal MHC Class I
In this administrative supplement we are requesting funds to increase the pace and achievement of scientific research of this project and to promote job creation. Specifically, we are requesting funds to provide the infrastructure to augment th
Emotion Dysregulation in Girls at Risk for Depression
The broad, long-term objectives of this work are to establish a practical and empirically-sound means to assess children's acute stress reactions after potentially traumatic events (eg, accidents, fires, disasters) and to expand our understandi
VALIDATING A CHILD ACUTE STRESS MEASURE IN ENGLISH AND SPANISH
The parent grant is a R01 that funds a randomized controlled trial of the Fostering Healthy Futures preventive intervention for preadolescent children placed in out-of-home care as a result of abuse or neglect.  The intervention is designed to
Fostering Healthy Futures Efficacy Trial for Preadolescent Youth in Foster Care
This supplement will be used to conduct additional analyses relevant to the aims of the parent grant. we propose to address the following questions: 1) How do healthcare and education services complement or substitute for each other in differen
Interstate variation in healthcare utilization among children with ASD
While cross-sectional studies show that drug abuse, impulsivity, serotonin dysregulation, and stressful life events are associated with suicide, data regarding the specific relationships among these factors are limited. A recent NIDA-sponsored
IMPULSIVITY AND BIOLOGICAL MARKERS FOR SUICIDALITY AND DRUG USE IN ADOLESCENTS
Detection and Care for Depression in the Perinatal Period Major depressive disorder (MDD) among women in pregnancy and the postpartum can have profoundly negative implications for women; fetal, infant, and child development; and the larger fami
Detection and care for depression in the peripartum
Project Summary/Abstract Neurological dysfunction is a significant complication of HIV disease. Despite the success of HAART in suppressing plasma HIV RNA, most antiretroviral drugs have poor CNS penetration and a reservoir of virus persists in
Env-Receptor Interactions in HIV-1 Infection of the CNS
ATMS US 29 from Briggs Chaney Road to Howard County Line
Mill and Overlay of Four Locations within Carver County
Mill and Overlay Holyoke/Highview Ave from Heritage Dr to Dodd Blvd (CSAH 9)
Replace BR 7142 With BR 01527 on CSAH 1 Over the Mississippi River Diversion Channel in Aitkin County
SCHOOL DISTRICT #1 MULTNOMAH COUNTY, OREGON (INC)
This award has two parts:  Part 1 is for Quality Improvement for $291,760 that will be used for repairs to sites, install and upgrade phone systems and replace classroom materials and furniture and part 2 is for COLA - $59,115 that will provide
COMMUNITY ACTION TEAM INCORPORATED OF COLUMBIA COUNTY, OREGON
Head Start 2009 ARRA COLA Quality Improvement funding consistent with the provisions of Section 640 (a)(5) of the Head Start Act
Head Start ARRA COLA to award cost-of-living adjustment increase to Early Head Start staff serving 204 infants, toddlers and pregnant women.  Also, ARRA Quality Improvement was awarded to the existing Early Head Start program operating in King
SOUTHERN OREGON CHILD AND FAMILY COUNCIL, INC
This award provides for ARRA Head Start Expansion of one class funded to serve 18 children age 3 to 5 in Medford, OR.  The Head Start program provides comprehensive services for low-income families and children with disabilities including early
OLYMPIC EDUCATIONAL SERVICE DISTRICT 114
Head Start ARRA Expansion. The overall purpose of this award is to expand Head Start home visiting services to unserved populations in Kitsap County and to partner with organizations that are most familiar in working with those populations. Thi
This award is provided for the conduct of ecological restoration work on 8 acres of coastal habitat on Maui, Hawai'i.
Multi-Service program on aging-to administer the assistance provided to the frail/elderly resident in our township Woodbridge Housing Authority - to replace roofs on building at the low income housing apartments Program Admin - program costs Ad
Community Development Stimulus Grant Program
LOGIQ P5 Ultrasound System, Transducers, and associated complenents, includes Installation and Training.
In FY 2009 COLA/Quality funds were provided to award a 3.06% cost of living adjustment salary increase to each Head Start employee; and an addtional 1.84% cost of living adjustment salary increase to each employee. A final COLA salary increase
HeadStart Quality Improvement and COLA  ARRA
Interstate 295 Northbound, Topsham to Gardiner
Design and construction assistance for the Honeyville City Culinary Water System Improvement Project.
Honeyville Culinary Water System Improvement Project
WORKFORCE INVESTMENT BOARD  OF PASSAIC COUNTY
This award is to made to State, city, county and Indian/Native American tribal governments (or organizations designated by such governments) in order to build the governments' capacity to partner with community-based and faith-bsed non-profits
ARRA 2009 Strengthening Communities Fund State, Local and Tribal Government Capacity Building program
This project provides additional funding for the existing Public Health Traineeship program. The funds are used to support degree seeking students who plan to work in the following public health shortage areas: biostatistics, epidemiology, envi
The Holyoke Health Center's award comprises three components:  1.  Renovation Project, 2.  Clinical and Non-Clinical Equipment Purchases and #3. IT Sytem Upgrade.  Component #1:  Consists of the renovation of approximately 4,250 square feet of
ARRA- Capital Improvement Program (CIP) El Pueblo Clinic Construction
CIP Grant Award is for the purchase of Xray Equipment and the implementation of  Electronic Health Records to include equipment, software and IT staff.  For the first quarter of 2011 there were no draws against the grant award.
The CIP will provide needed renovation for Whittier Street Health Center (WSHC), and ensure that equipment is updated to meet the many challenges and changes in WSHC?s service area. WSHC is a Joint Commission-accredited, urban community health
The New York State Public Health Workforce Taskforce assessed the public health system throughout the state and made recommendations to strengthen it by creating opportunities for training a competent workforce. The New York State Dental Public
RESIDENCY TRAINING IN DENTAL PUBLIC HEALTH
The Office of the State Superintendent of Education (OSSE) received funds through the American Recovery and Reinvestment Act of 2009 (ARRA) to pay costs associated with the distribution of USDA foods donated for use in The Emergency Food Assist
Nurse Faculty Loans intended to help increase the Nurse Educator population, thereby increasing the number of nursing students.
The purpose of the University of Washington (UW) NFLP (Nurse Faculty Loan Program) is to increase the number of qualified nursing faculty by providing loans to graduate nursing students at the UW. The UW School of Nursing offers four graduate n
This study could provide evidence that neuronal Cdh1 activity helps prevent the onset of Alzheimer's disease by maintaining neurons in a post-mitotic state by preventing cell cycle reentry which would lead to neuronal death. Understanding both
Neuronal CDH1 Regulation and Involvement in Synaptic Plasticity and Memory
The goal of the proposed project is to investigate how the aged brain responds to skilled motor training, both before and after stroke-like brain injury. This will be accomplished by first determining differences in behavior and neural plastici
Motor learning and neuroplasticity in an aged mouse model of cerebral ischemia
DESCRIPTION (provided by applicant): Dendritic cells (DCs) within peripheral tissues play a critical role in initiating immune responses towards peripheral antigens. Upon activation, these cells migrate through the tissue stroma towards lymphat
DENDRITIC CELL MIGRATION AND FUNCTION IN THE PREGNANT AND NON-PREGNANT UTERUS
La Crosse encephalitis virus (LAC), a devastating neurologic disease in children living in endemic areas like West Virginia and southwestern Virginia, is maintained through interactions between mosquito vectors and non-human vertebrate reservoi
Ecological impacts of forest disturbance on La Crosse encephalitis virus dynamics
The host response against microbial pathogens consists of the integrated actions of both the innate and adaptive immune systems. Protective immunity to viruses is dependent upon the complex interactions between cytokines and chemokines to regul
ROLE OF CHEMOKINES ON C8+ TAU CELL EFFECTOR FUNCTIONS DURING MCMV INFECTION
Effects of a Chlamydial ATP Consuming Enzyme on the Inflammasome:  This funding supports the tuition, benefits and stipend for two years of a graduate students expenses thereby, providing enough support for the completion of a PhD in Quantitati
Effects of a chlamydial ATP consuming enzyme on  the inflammasome
My research project aims to study host-pathogen interactions by identifying host factors that interact with and, consequently, restrict viruses. Through a combination of genomics, evolutionary biology and virology, we can predict specific host
The Role of CyclophilinA in the Evolution of Retroviral Restriction
Astrocytes play a fundamental role in signaling, maintenance and protection of the brain. Data generated in the sponsor's laboratory suggest that the neuroprotective ability of astrocytes diminishes with age. It was also discovered that the pur
IMPACT OF GLUTATHIONE PRODUCTION IN ASTROCYTES ON NEUROPROTECTION DURING AGING
Recently, cerebral microvessel disease has been identified as an important component of Alzheimer's disease. The mechanism of interaction between the diseases is still unclear in part because animal models of microvascular disease are lacking.
ROLE OF MICROVASCULAR LESIONS IN ALZHEIMER'S DISEASE
The general goal of this proposal is to develop an animal model for examining the mechanisms through which social support may be protective against various challenges, especially in aging.  We will focus here on the hypothesis that oxytocin (OT
The protective effect of oxytocin on social isolation physiological mechanisms
Acute inflammation is a self-limiting response driven by the cells of the innate and adaptive immune systems that serves to rid the body of invading pathogens. Chronic inflammation on the other hand, represents an immune response that fails to
Epigenetic regulation of Th17 and Th1 cell lineage differentiation
Dendritic cells (DCs) are potent antigen presenting cells (APCs) due to the ability to stimulate nai've T cells with antigen. DCs are also a promising new source of vaccine development. Endocytosis and migration are two key processes in the abi
Respiratory syncytial virus (RSV) is a major etiologic agent of lower respiratory tract infection in children and the elderly. In the U.S., RSV can be detected in 43% of pediatric patients hospitalized with bronchiolitis and 25% with pneumonia.
Human Host Responses to Respiratory Syncytial Virus Infection
A T cell response is initiated by T cell receptor (TCR) activation through recognition of foreign antigen displayed on the surface of an antigen presenting cell (APC) and results in the directional secretion of certain cytokines or cytolytic fa
MECHANISTIC ANALYSIS OF T CELL MTOC REORIENTATION WITH A PHOTOACTIVATABLE ANTIGEN
Clostridium difficile is a bacteria that causes epidemic disease throughout the United States and has become a major public health concern in health care facilities and the community. Understading the ways in which C. difficile causes disease b
The Relative contribution of TCDA & TCDB to C. difficile associated disease
Effect of a viral replicon adjuvant on dendritic cell activity.  It has been demonstrated in this lab that infectious, non-propagating replicon particles from Venezuelan equine encephalitis virus (VEE) act as an adjuvant when co-delivered paren
Effect of a viral replicon adjuvant on dendritic cell activity
This proposal aims to test  the hypothesis that  specific trafficking mechanisms target pulmonary memory lymphocyte homing to lung,  and to identify the adhesion and chemoattractant receptors involved.  Published studies are consistent with lun
SPECIFICITY AND MECHANISMS OF LUNG LYMPHOCYTE HOMING
Infection of humans with Plasmodium species, the parasites that cause malaria, remains a significant global health problem. There are approximately 300-500 million new cases of malaria each year, which results in the death of 1-3 million people
Defining Optimal Adaptive Immunity for Resistance to Plasmodium Sporozoites
Type 1 diabetes Is an autoimmune disease that occurs when autoreactive T cells attack and kill the insulin producing cells of the pancreas. Currently, the disease is treated by repeated insulin Injections, however there is no cure. Prolonged pe
DRAK2-A POTENTIAL THERAPEUTIC TARGET FOR TYPE 1 DIABETES
Large-scale genome sequencing has revealed that some organisms have genomes that encode for an astonishing number of proteins with domains of extremely low sequence complexity. Although the folding and function of these domains is poorly unders
Folding of N-Rich erythrocyte remodeling proteins of malarial parasite
The movement of leukocytes across the endothelial cell layer of blood vessels is critical to mounting an effective inflammatory response but is also a connected pathology of such diseases at athersclerosis, mutliple sclerosis and arthritis. Thi
Isolation of the LBRC and Characterization of Its Protein Components
This award will provide partial funding for renovation of Bldg 12 at the JHU farm to provide space for the expansion of an NIH supported colony of pigtailed macaques. These animals are used in NIH funded programs at Johns Hopkins and other inst
RENOVATIONS AT JOHNS HOPKINS UNIVERSITY TO SUPPORT EXPANDED MACAQUE PRODUCTION
National Jewish Medical and Research Center is a small, private, non-profit hospital that has developed an international reputation as the top Respiratory Hospital in the United States the past 10 years according to U.S. News and World Report.
Upgraded Equipment and Expansion of Cage Wash Facilities
The Salk Institute for Biological Studies is a non-profit research institution devoted to making fundamental discoveries in the life sciences, the improvement of human health and the training of future generations of researchers. Salk is arguab
This grant application addresses necessary facility improvements at NYU’s two main animal facilities at the Washington Square Campus critical to support funded investigators in Neural Science, Biology, and associated departments of the Univer
NYU Proposed Animal Resource Improvements
With this award, Boston HealthNet (BHN) implemented the CHART-Plus Project. The purpose of the project was to vertically integrate the EMRs of eight BHN community health centers (CHCs) with that of their partner hospital, Boston Medical Center
Community Health Automated Record Technology (CHART) Plus
In March 2009, North Side Christian Health Care Center (NSCHC) was awarded New Access Points in Programs Funded Under the Health Centers Consolidation Act of 1996, CFDA Number 93.224, for Section 330(e), 330(h), and 330(i) funding. With the two
Increased demand for services (IDS) funding is used to support 1.2 FTE saved jobs as well as purchase certain small equipment that will interface with our new EMR.
The Increased Demand for Services (IDS) Grant provides financial support to address greater patient demand for health center services by uninsured populations that rely on health centers for their treatment needs.   The $ 451,879.00 award will
The CHC has an immediate need for more provider time.  By increasing the current General Practitioners time to full-time the CHC should see 1,875 more encounters during the grant period for an estimated 300 new unduplicated patients to be seen.
As a result of this ARRA funding, we are open on Saturday's to provide medical and dental services to new and existing patients.    This quarter we served 1,581 new patients and 639 new unduplicated patients.
PROJECT DESCRIPTION:  Funds will be used to hire an additional full time dentist, an additional full time dental hygienist, clinical and administrative support staff.  IDS funding will result in a total of 8.4 new jobs.  Services will be provid
The Increased Demand for Services grant award allows funding to create/retain healthcare jobs within our organization so as to eliminate barriers to care, particularly for the uninsured. Our $142,936 award allowed us to hire a 1.0 FTE family ph
The increase in demand for services grant had the following goals: a) increase patient visits as well as b) increase the number of uninsured patients we see.   By achieving these goal, we can better monitor health outcomes and improve the patie
he central theme of the Program Project is to understand the innate host defense mechanisms against inhaled pathogens by the two pulmonary collectins, surfactant proteins A and D (SP-A, SP-D). This understanding is important not only in the con
Collectins and Innate Defense Against Inhaled Pathogens
Human genetic research has made remarkable progress in understanding the underlying genetic architecture of numerous human genetic traits.  The underlying genetic lesions for thousands of Mendelian traits have now been identified and hundreds o
Recruitment of Faculty for Genetic Aging Research
In this application, we propose to create a multi-disciplinary Center for Skin Stem Cell Biology based within the Department of Dermatology at the College of Physicians & Surgeons at Columbia University. This center will build on the existing r
Biomedical Research Core Center on Skin Stem Cells
This project aims to support the hiring of a new tenure track Assistant Professor to perform research on vascular disease and pulmonary hypertension complications in patients with systemic sclerosis (SSc) in an interdisciplinary environment, fo
Translational Vascular Biology in Autoimmune Diseases
The purpose of the American Recovery and Reinvestment Act of 2009 is to create jobs, and for NIH awards to fund science in pursuit of improving the length and the quality of the lives of U.S. citizens, while at the same time stimulating the eco
WHOLE GENOME METHYLATION LANDSCAPE OF BREAST CANCER
Pediatric asthma is increasingly common among minority children, and results in considerable health care disparity.  The parent grant ‘Community Partnerships to Reduce Asthma Disparities’ (R01 NR08524, E. McQuaid, PI) established a Communit
COMMUNITY PARTNERSHIP TO REDUCE ASTHMA DISPARITIES
'Purpose:  To understand and prevent seizure-induced learning and memory deficits in children with severe epilepsy.  Abstract: The studies proposed in our original application are based on the premise that recurring seizures in early-life contr
In all vertebrate, the autonomous spinal networks that generate movements are referred to as central pattern generators (CPGs). The principal neurons in the locomotor CPG include ipsilateral rhythmogenic interneurons, (rhythm generators), commi
Abnormal development of the nervous system is thought to underlie many complex neurological disorders. In the past decade, research in several vertebrate organisms has shown the bHLH transcription factor Ascl1 (previously Mash1) is essential fo
Regulation and Function of Ascl1 (Mash1) in Neural Development - ARRA Stimulus Summer Student
Mechansisms of preferential reinveration Over 40,000 Americans suffer peripheral nerve injury each year. Of these, only 10% will regain normal function. Results of surgical treatment are compromised by the limited ability of peripheral nerve to
NOT-OD-09-058: NIH Announces the Availability of Recovery Act Funds for Competitive Revision Applications Gamma-aminobutyric acid type A receptors (GABAARs) mediate synaptic inhibition in the brain and are modulated by a variety of clinically i
ARRA Structure of the GABA A Receptor Binding Sites
Loss of white matter at the site of traumatic spinal cord injury (SCI) interrupts critical ascending and descending tracts and thus precludes normal function in the spinal cord distal to the site of injury. In the last project period we identif
CELLULAR INTERACTIONS IN SPINAL CORD CONTUSION
The broad, long-term objectives of this project are to gain novel knowledge about a highly specialized calcium (Ca2+) channel - the inositol (1,4,5)-trisphosphate receptor (InsP3R). The proposed studies are fundamental to understanding Ca2+ sig
Structure-Function of Inositol Trisphosphate Receptor - ARRA Stimulus Admin Suppl
PREDICT-HD is an international 30-site observational study of persons at-risk for Huntington's disease (HD). PREDICT-HD capitalizes on two unique aspects of HD among neurodegenerative disorders the ability to know in advance who will develop th
Neurological Predictors of Huntington's Disease: Cell Lines
The main goals of the project are to develop a method for blocking granule cell axon sprouting and synaptogenesis and then determine whether such blockade reduces epileptogenesis in a rodent model of temporal lobe epilepsy. This request is for
Dentate Gyrus Circuitry In Temporal Lobe Epilepsy
Our experimental plan in our Stimulus award is to test the hypothesis that the R69C mutation in myelin protein zero (MPZ) causes a severe dysmyelinating inherited neuropathy in humans by disrupting the unfolded protein response; a process in wh
Prior research has shown that neurons within the spinal cord can support some simple forms of learning. Learning in the isolated spinal cord can be studied by cutting communication with the brain by means of a thoracic transection. Transected r
LEARNING WITHIN THE SPINAL CORD:  CLINICAL IMPLICATIONS
The proposed experimental plan is an extension of our previous study aimed at defining the histone modifications responsible for the differentiation of progenitors into oligodendrocytes, the myelin-forming cells of the central nervous system. I
HISTONE DEACETYLATION IN OLIGODENDROCYTE DIFFERENTIATION
The initial event in the life cycle of a virus is its interaction with receptors present on the surface of a cell. Understanding these interactions is important to our understanding of viral tropism, spread, and pathogenesis. The human polyomav
VIRUS-HOST CELL INTERACTIONS IN AIDS-ASSOCIATED PML
Neuronal nAChRs are composed of a number of subtypes as classified by their diverse pharmacology and distribution in the central and peripheral nervous system. We propose to study one such subtype, the neuronal a-bungarotoxin binding receptor (
THE NEURONAL ALPHA-BUNGAROTOXIN BINDING SITE
Spinocerebellar ataxia type 1 (SCA1) is an untreatable fatal autosomal dominant neurodegenerative disorder caused by the expansion of a glutamine repeat within the SCA1-encoded protein ATXN1. Previous work showed that ATXN1 is modified by phosp
This award sustains and extend the characterization of parkin interacting substrates. In particular this supplement is allowing the continuation of important studies focused on the identification and characterization of the Parkin Interacting S
THE ROLE OF PARKIN IN PARKINSON'S DISEASE
During this period, we made good progress on completing the objectives of R000272. We: (1) used a BioTek-2 plate reader to establish a full time course of cell death (immediately-2 days post injury) at varying levels of injury (moderate to seve
ALTERED EXCITATORY NEUROTRANSMISSION AFTER BRAIN TRAUMA
One long term objective is to understand the biochemical and cellular mechanisms of the regulation of the sodium pump (Na,K-ATPase), which is the driving force for cerebrospinal fluid (CSF) secretion. The other is to understand how that regulat
Cellular/molecular Na,K-ATPase regulation in choroid plexus
ARRA Summer Research Experience: Student
Our recent studies have demonstrated that conventional isoforms of protein kinase C (PKC) are key signaling components in the pathways that mediate the inhibitory activities of both myelin components and astrocyte-derived chondroitin sulfate pr
PKC inhibition-mediated spinal cord regeneration
Determine if the superinfecting HY TME agent persists in animals when blocked by prior infection with the DY TME agent.  Determine if HY TME agent emergence is inevitable.  The data generated  will further refine the parameters of prion strain
This award is issued in response to Notice OD-09-060, Recovery Act Administrative Supplements Providing Summer Research Experiences for Students and Science Educators.One of the most pervasive problems for stroke survivors is movement deficits.
ERROR-ENHANCED LEARNING & RECOVERY IN 2 & 3 DIMENSIONS
The overall purpose of the award is to employee two undergraduate summer students to give them experience within a laboratory environment to help in the educational experience and to collect data relevant to the Aims of the parent award.
ASTROCYTES, HIF-1A AND NEURONAL SURVIVAL DURING STROKE
Our long term aim is to use a genetic approach in Drosophila to understand molecular mechanisms of motorneuron fate specification and differentiation. In this proposal, we focus on mechanisms linking motorneuron fate to axon guidance. In a larg
Linking Motorneuron Fate and Connectivity in Drosophila
Our studies supported by the parent R01 grant have identified a novel ion channel complex that controls neuronal excitability and may be involved in pathophysiological conditions such as apnea, paralysis, seizure  and epilepsy. The requested fu
SODIUM LEAK CHANNELS AND REGULATION BY NEUROTRANSMITTERS
Spinal cord injury (SCI) is a devastating condition which results in lifelong disability. To date there exists no treatment that can restore significant function to persons with SCI. We have previously demonstrated that a combinatory strategy o
AXON REGENRATION: SYNERGISTIC ACTIONS OF THE MAPK AND CYCLIC AMP PATHWAYS
Mitochondria provide energy, buffer calcium, and sequester cell death-inducing molecules, and mitochondrial dysfunction is implicated in various neuropathologies. Especially in neurons, mitochondria are highly dynamic organelles that constantly
Regulation of Mitochondrial Fission/Fusion by PP2A and PKA in Neurons
Diabetes is a risk factor for cerebrovascular disease, cognitive impairment, and related dementia. Data derived from populations suggest that several comorbidities of diabetes increase the risk for cognitive impairment, structural brain changes
Genetic Epidemiology of Cerebrovascular Disease and Cognition in Diabetes
To date, this supplement has helped stimulate the U.S. economy by providing funds for the hiring of Dr. Antoine Muchir as an Associate Research Scientist at Columbia University.  The hiring of Dr. Muchir as well as additional funds for supplies
Nucleocytoplasmic Interactions and Dynamics in Emery-Dreifuss Muscular Dystrophy
The overall purpose of the award is to provide undergraduate students with experience in an NIH-funded biomedical research lab. In addition to the obvious goal of giving summer jobs to deserving young people, There are two major goals. First, t
NOVEL COMPOUNDS THAT OVERCOME GLIAL INHIBITION OF AXONAL REGENERATION
Depression is a highly prevalent in Parkinson's disease (PD) and is often said to contribute more to the lowered quality of life than the debilitating motor symptoms. Although the etiology of depression in PD is unknown, understanding the poten
STRESS-INDUCED DEPRESSION AND PARKINSONIAN SYMPTOMOLOGY
Our previous work suggests that the protein 'Sunday Driver' (syd) organizes a damage surveillance system in peripheral neurons. In this proposal, we will further test the role of syd in conveying vesicle packages and signaling molecules along a
MECHANISMS REGULATING VESICULAR AXONAL TRANSPORT FOLLOWING NERVE INJURY
Rett Syndrome is a devastating developmental disorder due in most cases to mutation of the gene Mecp2. Affected individuals lose or fail to develop many normal language, motor and cognitive abilities. Mutant mice lacking part or all of the gene
Circuitry, plasticity and gene expression in a mouse model of Rett syndrome.
The central question of the parent award is to understand the relationship between cortico-striatal synaptic function and pathological behaviors. The initial step toward this was to understand the striatal synaptic defects created by deletion o
Cortico-striatal synaptic defects and compulsive motor behaviors in mice
Bacterial pneumonia continues to be a leading cause of death and warrants improved treatment strategies. Recruitment of neutrophils into the lungs is one of the most important defense mechanisms in the initial host defense against bacterial inf
Neutrophil Accumulation in Bacterial Pneumonia
Recognizing their advantages for comparative medicine, NIH supports a substantial amount of research on teleost fish, including zebrafish, medaka, stickleback, and others. Teleost models of human disease provide distinct advantages for analyzin
Resources for Teleost Gene Duplicates and Human Disease
his proposal describes a research plan to biosynthesize HSAF (dihydromaltophilin), a broad spectrum antifungal natural product with a new mode of action. HSAF was isolated from Lysobacter enzymogenes C3, a bacterium used in the biological contr
Biosynthesis of HSAF, an antifungal natural product with a novel mode of action
Our long-term objective is to conduct a large, island-wide, population-based, genetic-epidemiologic study of familial colorectal cancer in Puerto Rico.  The overall goal of this porposal is to determine the feasibility for implementation of a p
FAMILIAL COLORECTAL CANCER REGISTRY IN PUERTO RICO: A FEASIBILITY STUDY
The project involves testing the role of Runx1 in intestinal cancer in mouse models.
Pla2g2a, Runx1 and Colorectal Cancer Risk
This research project will investigate the neural circuits underlying fundamental cognitive learning abilities in deaf children with cochlear implants. This knowledge is important because it will help elucidate why many deaf children display la
Implicit Sequence Learning in Deaf Children with Cochlear Implants
This supplement application proposes to augment the RO3 Modern Genetic Testing in the Pediatric Critical Care Environment (Upperman, PI) awarded by the NICHD in July 2009. We propose to enhance data collection activities in Phase 1 to include f
Modern Genetic Testing in Pediatric Critical Care Environment
This work proposes to expose medical students to abnormal clinical conditions through the use of immersive virtual patients (VPs).  Immersive VPs are highly interactive, computer-generated, life-size virtual 3D characters.  As medical educators
Immersive Virtual Patients with Abnormal Clinical Conditions for Medical Student
The long-range goal of this research proposal is to elucidate how rhinovirus (RV) activation of macrophages contributes to the exacerbations of asthma. Virus-induced asthma is resistant to therapy; therefore knowledge about the cellular process
LEUKOCYTE SIGNALING IN VIRUS-INDUCED ASTHMA EXACERBATION
Cathepsins B, D, and K have been suggested to play important roles in the metastatic potential of several types of cancer, and have been implicated in the pathology of a wide variety of diseases. Most assume cathepsins B, D, and K to be restric
AREA: SYNTHESIS AND EVALUATION OF NEW CATHEPSIN B, D, AND K INHIBITORS
The objective of this project is to develop neomycin-TFOs that directly target the ets2 gene, found amplified in breast and prostate cancer. The proposed work will overcome important challenges such as TFO affinity to the duplex and delivery to
Adolescence marks a critical period in development in which individuals are particularly vulnerable to developing problems with substance abuse and dependence. Using an animal model, we will examine the effects of social contact with a companio
Social and Environmental Influences on Opioid Sensitivity
A supplement is requested to our current grant Biophysical Analysis of Enzyme-Inhibitor Interactions (1R15GM073662-01).  The supplement will allow us to: 1) identify primarily single molecule rupture events between carbonic anhydrase enzyme and
Biophysical Analysis of Enzyme Inhibitor Interactions
The specific aims of this investigation are threefold:  1) determine in wild-type yeast whether long-term immobilization alters chronological lifespan and global gene expression relative to aging planktonic cultures; 2) establish, relative to w
Discovery of genes that extend yeast lifespan:  Aging in immobilized cell reactors.
The synaptonemal complex (SC) is a proteinaceous scaffold that juxtaposes homologous chromosomes (homologs) during the pachytene stage of meiosis.  Crossovers/chiasmata form in the context of the SC mediating homolog segregation to opposite spi
Functional analysis of the synaptonemal complex
Cytochrome P450 enzymes in humans are a family of heme-containing enzymes involved in metabolism of steroids, vitamins, eiconsanoids, and xenobiotics such as drugs, complex plant alkaloids, carcinogens, and other small molecules. With the seque
MECHANISM-BASED INHIBITION OF P450 2D6 BY A PIPERAZINE-CONTAINING COMPOUND
To support small scale research projects conducted by faculty in primarily baccalaureate degree-granting domestic institutions. Awards are for up to $75,000 for direct costs (plus applicable indirect costs) for periods not to exceed 36 months.
Cloning and Analysis of a Gamete Fusion Gene
Body size can be altered by pituitary growth hormone, with the largest and smallest nonobese humans varying by about 10-fold in body mass. Organ sizes generally vary with body size, although there are indicators of local organ size regulation
SUPPRESSION OF TADPOLE LIMBS: A MODEL FOR ORGAN SIZE REGULATION
or differentially encodes new meanings associated with a previously learned defensive reaction to fear. The work may identify more effective ways to reduce or eliminate learned fears and will advance the development of treatments for deficits
NEURAL MECHANISMS OF EXTINCTION AND SPONTANEOUS RECOVERY
People/Families with of People with Psychological Disabilities
DESCRIPTION (provided by applicant): The overall goal of the present work is to characterize the cell and molecular mechanisms that regulate neural and vascular cell interactions during development. The central objective of this work is to det
The CellsZcope is an automated instrument that allows for a more reliable monitoring of electrical integrity of cellular monolayers in real time. In addition, the paracellular permeability to solutes, another measure of integrity of brain endot
Alcohol mediated blood brain barrier dys
(healthspan) in the powerful experimental model C. elegans. In this animal, conserved genes can be readily manipulated to address specific hypotheses regarding their activities. Moreover, nearly all the C. elegans microRNA genes are likely to
MicroRNA Modulators of Dietary Restriction
Rickettsia felis is recognized as an emerging flea-borne rickettsial agent. Within the Specific Aims of the parent grant we have discovered a very interesting association between microbiota of fleas and their potential to transmit Rickettsia fe
Role of Fleas in Transmission of Rickettsia:Ecology of Flea-Borne Spotted Fever
Louisiana State University School of Vet Medicine
that the conserved, essential genes of HSV-2 are also protective against HSV-2 in animal models and to provide the justification for pursuing more comprehensive preclinical studies of immunity and protection using this novel class of antigens.
DEVELOPMENT OF A NOVEL VACCINE AGAINST HERPES SIMPLEX TYPE 2
Streptococcus agalactiae (group B Streptococcus; GBS) is a leading cause of invasive infections such as pneumonia, sepsis, and meningitis in neonates. GBS is also an emerging cause of disease among the immunocompromised and elderly. Regulation
MTAR-REGULATED VIRULENCE IN STREPTOCOCCUS AGALACTIAE
In our original proposal, we set out to adapt genetic tools for working with the Category A select agent pathogen Yersinia pestis such that the use of antibiotic resistance markers could be reduced or eliminated. This research is necessary to e
ARRA: Development of Novel Genetic Tools for Metabolic Selection in Yersinia pestis
Seeking additional funding to support out effort toward the discovery of inhibitors of influenza A virus RNA polymerase complex assembly by targeting PB1-PB2 and PA-PB2 interations, which fits well in the overall scope of the parent R21 grant.
Over 4 million individuals were newly infected with HIV in 2006 with sexual transmission the predominant mode of infection worldwide, highlighting the need for effective prevention strategies. Unfortunately clinical trials to date, with the fir
HIV INTEGRASE AS A TARGET FOR TOPICAL MICROBICIDE DEVELOPMENT
The overall purpose of this award is to support undergraduate summer research regarding how respiratory viruses cause inflammation.  By identifying host factors leading to inflammation upon virus infection, novel therapies to reduce the extent
.  The goals of the project are to provide mentorship to undergraduates considering careers in the biomedical sciences and to obtain findings addressing the aims of the parent grant.
Ubiquitin and Cellular Factors in Coronavirus Assembly
with inducible pigmentation. Like in humans, the fair-skinned phenotype in our animal model is caused by defective signaling in melanocytes by the melanocortin-1 receptor (MC1R), a protein that mediates adenylate cyclase activation and cAMP ge
Coleus forskohlii extract: melanization and UV protection by a natural product
Matrix metallo-proteinases (MMPs) are often present in high levels in cancer such as tumors of the skin, breast, thyroid, cervix, lung, colon and prostate, but absent in normal tissues. MMPs are enzymes that are capable of chewing through the p
NEAR INFRARED IMAGING OF MMP-2/MM-9 WITH A HIGHLY SPECIFIC OPTICAL PROBE
The overall goal of this project is to develop new functional EPR probes of enhanced stability for in vivo EPR spectroscopy and imaging of pH, one of the most important parameters in the biochemistry of living organisms. pH-sensitive nitroxyl r
(ARRA) Spin probes in semipermeable nanospheres: EPR spectroscopy and imaging of tumor pH
NOT-OD-09-058: NIH Announces the Availability of Recovery Act Funds for Competitive Revision Application The immune system has the potential to eliminate altered neoplastic cells with incredible specificity. A consistent in-frame deletion in th
EFFECT ON IL-2R ANTIBODY ON REGULATORY T-CELLS IN PATIENTS WITH MALIGNANT GLIOMAS
Award deobligated because PI did not hire named person on the diversity supplement.
Microfluidic Devices for Molecular Characterization of Cancer Cells at the Single-cell Level
DESCRIPTION (provided by applicant): Increasing numbers of persons who have co-occurring mental and substance use disorders (CODs) and other health-related conditions are involved in the criminal justice system, and have placed an enormous stra
USF CENTER ON CO-OCCURRING DISORDERS, JUSTICE, & MULTIDISCIPLINARY
Two new investigators will be hired into tenure track positions (with a minimum funding for 4 years beyond the grant). The searches for these positions were pre-empted by a hiring freeze. Additional economic impact comes from two additional ful
Emergence, Structure and Neurobiological Basis of Typical and Atypical Language
The existing University of Florida Center for Smell and Taste (UFCST) will provide the basis for a Biomedical Research Core Center for Smell and Taste at the University of Florida (Core Center).  The existing research infrastructure and environ
The University of Florida Biomedical Research Core Center for Smell and Taste
The strategy was decided to build research capabilities on the existing tissue engineering strengths at the University of Pittsburgh which was lacking a concerted effort in the field of craniofacial regeneration. During its short history, CCR h
New Faculty for Craniofacial Tissue Engineering and Biology
The University of Southern California (USC) P30 project is directed at recruiting junior faculty members whose research interests are complementary to our goal of enhancing our understanding of the polydisciplinary events shaping craniofacial m
Interdisciplinary New Faculty Recruitment in Craniofacial Development
The goal of this award is to develop a Core Center in Quantitative Biology at Oakland University. To strengthen this Core Center, a new faculty member will be recruited to perform interdisciplinary and translational research. This Core Center w
DESCRIPTION (provided by applicant): This proposal aims to strengthen the biophysics core at the University of Missouri comprised of the Department of Physics and Astronomy, the Dalton Cardiovascular Research Center, and the Biochemistry Depart
Hiring Plan for Biophysics Core Faculty Position
DESCRIPTION (provided by applicant): This proposal seeks support for new faculty recruitment to enhance research resources for the Nanomedicine Research Center (NRC) at the University of South Florida College of Medicine, whose mission is to se
NANOMEDICINE RESEARCH CENTER CORE (NRCC)
Cardiovascular disease is a leading cause of morbidity and mortality, accounting for upwards of 900,000 deaths annually in our country and many millions more worldwide. NYU School of Medicine has identified improved cardiovascular health as one
NYU Core Grant for Cardiovascular Faculty Recruitment
This goal of this grant is to recruit a talented new faculty member that would enrich the collaborative group of dynamic cardiovascular research faculty and trainees at UC Davis that crosses several departments and colleges.
Mortality of patients with chronic lung diseases continues to ncrease in the United States. Understanding the mechanisms of how the lung responds to injury and how this leads to abnormal lung healing is key to the development of novel therapeut
Recruitment of New Faculty to Enhance Research in Lung Biology
This grant supports a new independent investigator in molecular cardiology research.  The new investigator will study genetic and molecular aspects of congenital heart defects (CHDs) with the goal of providing new insights into the mechanisms u
New Cardiovascular Research Scientist for Molecular and Cellular Biology Core
The Gene and Cell Therapy Program (GCTP) at Indiana University is a highly interactive group of investigators with a 15-year history of multi-departmental interaction and collaborative research. The program has a focus on the genetic manipulati
New Faculty Recruitment to the Indiana University Gene Therapy Program
The Vanderbilt Program in Drug Discovery (VPDD) is a world class effort fully focused on discovery and characterization of novel molecules to evaluate new potential treatment strategies for CNS disorders. The VPDD has had tremendous success in
Recruitment of In Vivo Neuropharmacologist to Support CNS Drug Discovery Research
The Center for Learning and Memory (CLM) at The University of Texas at Austin engages in a multidisciplinary approach to the study of the neurobiology of learning and memory. The CLM facilitates the exchange of ideas and expertise across differ
UT Austin Center for Learning & Memory Faculty Recruitment Proposal
Purpose of this application is to form a partnership between the NIH and Tufts Neuroscience Department which will allow the expansion of our program by hiring additional tenure-track assistant professors.  With funds from this award and from Tu
FACULTY RECRUITMENT TO TUFTS NEUROSCIENCE
A new Assistant Professor will be recruited to the Department of Physiology of the University of Wisconsin School of Medicine and Public Health. The Department will recruit an outstanding researcher in the field of Synaptic Function, and this n
ARRA Assistant Professor of Physiology in Synaptic Function
During atherogenesis, eicosanoid biosynthesis is altered by mechanisms that are not well understood.  Consistent with the essential nature of eicosanoid equilibrium, prostaglandin H2 synthase (PGHS, colloquially known as COX) enzymes produce pr
Eicosanoid Regulation in Atherosclerosis: Involvement of Inducible NO Synthase
The prevalence of heavy alcohol consumption and associated problems is elevated among college students. Alcohol-related problems are multifaceted with a complex etiology. Alcohol problems are commonly organized into two related dimensions, abus
Self-Control and Alcohol Problems: Psychological Mechanisms.
414 East Clark St. Department of Psychology
The broad, long-term objective of the proposed research is to elaborate an approach for a comprehensive analysis of data on health-related changes in aging individuals by developing tools for integrative analyses of distinct types of longitudin
New Methods of Studying Aging, Health and Longevity: Combining Longitudinal Data
This project will focus on the triad of relationships among the older surviving mother, a focal adult child, and the child's sibling, six to nine months after the death of an elderlyfather. The focus will be on the cultural meaning and the proc
The Meaning of Death of the First Elderly Parent: A Family Perspective
(CMS, 2008).  This list provides clinical research topics for which there are significant knowledge gaps.  This proposal is also consistent with the interests of the National Institute on Aging's (NIA) Behavioral and Social Research Program's
Racial Disparities in Older Adults: Impact of Medicare Part D
The quality of care delivered to frail elders residing in nursing homes remains an important and perplexing issue in American health policy. Given the preferential tax treatment afforded nonprofit firms, there has been much interest among polic
Selection and the Quality Impact of Nursing Home Ownership
Caloric restriction (CR) extends life-span and delays diseases in animal models. This remarkable observation has been difficult to translate into human health benefits, for two primary reasons. First, a life-time of food deprivation and reduced
Response to and Signals of Caloric Restriction and Intermittent Feeding Regimens
Drug Targets for Tuberculosis. Despite the availability of antibiotics, tuberculosis remains a major cause of death worldwide. Current drugs, while effective and inexpensive, are quite difficult to administer because of the very extended course
Mycobacterium tuberculosis (Mtb) grows in human macrophages, the principal host cell, where it occupies a niche allowing it to replicate without being recognized by the host. Attenuated Mtb induce apoptosis of the host macrophages resulting in
Regulation of Apoptotic Envelope Formation by MTB in the Host Macrophage
The identification and cloning of the CRAC channel by us and others (CRACM1/Orai1) has defined the basic molecular components required for store-operated calcium influx. Mutational analysis demonstrated that CRACM1/Orai1 homopolymerizes and tha
STORE OPERATED CALCIUM INFLUX IN CELLS OF THE IMMUNE SYSTEM
Although chromosomal toxin-antitoxin (TA) systems have been known for some time in Gram- bacteria, TA modules in Gram+ species have been understudied. There are eight families of TA systems all of which operate under a similar principle, with a
The toxin-antitoxin system of Staphylococcus aureus
Mycolic acids and multimethyl-branched fatty acids are found uniquely in the cell envelope of pathogenic mycobacteria. These unusually long fatty acids are essential for the survival, virulence, and antibiotic resistance of Mycobacterium tuberc
Structure-Based Tuberculosis Drug Design Targeted at Acyl-Coa Carboxylase
An enzyme that modifies sialic acid moieties known as Sialic acid acetyl esterase regulates the strength of signaling from the antigen receptor on B lymphocytes. Mutation of this gene in mice leads to enhanced B cell receptor signaling and auto
Mutations in the SIAE Gene and Susceptibility to Autoimmune Diseases
Successfully eradicating HIV infection will require understanding how cellular reservoirs that poorly express virus are established and maintained, as well as determining whether these populations can be purged of HIV. This proposal focuses on
Regulation of HIV Transcription Elongation
1.  The objective of this application is to understand the mechanisms responsible for coronary sclerosis and cardiac dysfunction induced by total body irradiation (TBI), and to identify and develop medical countermeasures to mitigate and/or tre
To carry out their immunological function, lymphocytes must travel to specific locations within the body. The homing of lymphocyte sublines is controlled through a complex molecular zipcoding, in which surface receptors on lymphocytes bind liga
SIMULATION OF LYMPHOCYTE ADHESION USING INTEGRATED ADHESIVE DYNAMICS
The goal of this proposal is to change this landscape in Trypanosoma cruzi drug development.  We propose the development of a consortium of academic laboratories and pharmaceutical companies who will investigate a variety of independently ident
Drug Discovery Consortium for Chagas Disease
This project will explore the activation of human endogenous retroviruses (HERVI to induce immunity to HIV-1 and prevent or ameliorate infection. Small molecules capable of activating HERV expression will be identified, and their ability to sti
Cross-reactive HERV Immunity to Combat HIV-1 Infection
Semen contains cationic amyloid fibrils derived from proteolytic cleavage fragments of prostatic acid phosphatase (PAP) that efficiently capture HIV-1 particles. These fibrils have been termed semen-derived enhancer of viral infection (SEVI) an
It's not often said but it must be admitted: current therapy for polyarticular juvenile idiopathic arthritis (JIA) is little more than an exercise in 'chasing failure.' That is, medications are added or doses adjusted only after a child has fai
DYNAMICS OF THERAPEUTIC RESPONSE WITHIN THE TREAT TRIAL
reverse translational itinerary and is a fundamental part of the project, as it will dissect and define the mechanisms of tolerance from a unique collection of samples already obtained from a NIH-funded Phase II trial.
Immune Tolerance in the Therapy of Rheumatoid Arthritis
Costameres are structures at the surface of striated muscle that align the sarcolemma regularly with nearby myofibrils and transmit contractile force laterally, through the membrane to the extracellular matrix. Costameres must therefore be link
Intermediate Filaments & Costamere Structure & Function
Multiple myeloma (MM) is still incurable - causing the death of 10,000 Americans annually. Currently, glucocorticoids and the proteasome-inhibiting drug PS-341 (Bortezomib/Velcade) rank among the most effective agents in myeloma therapy. Given
The goal of  this proposal  is  to establish pre-clinical evidence of synergism between glucocorticoids such as dexamethasone  (Dex)  and  the  MEK  inhibitors  such  as  PD184352  in  the  induction  of  apoptosis  in  acute lymphoblastic  leu
Apoptosis Induced by Glucocorticoids and MEK1/2 Inhibitors in Leukemia
The aim of this funded R21 proposal is to study the role of dietary supplement selenium (Methylselenocysteine or MSC) in supranutritional doses in retarding cancer growth and synergistically enhancing chemotherapeutic efficacy in combination se
Targeting the proteasome to overcome therapy resistance in B-NHL
Patients with advanced cervical cancer are treated with chemoradiation. Pretreatment positron emission tomography (PET) with 18F- fluorodeoxyglucose (FDG) is routinely utilized for these patients to determine the extent of their disease, to aid
INTRA-TUMORAL METABOLIC HETEROGENEITY OF CERVICAL CANCER
Epstein Barr virus nuclear antigen EBNA3C is a latent viral nuclear antigen essential for B cell transformation in vitro. This EBV antigen has been linked to the specific regulation of a number of cellular events which include regulation of tra
Dramatic advances in cancer treatment will depend on identifying new targets for therapeutics. Here we propose as a candidate target a novel phosphoinositide signaling pathway that we have discovered. We have identified a pathway involving the
TARGETING A NOVEL PHOSPHOINOSITIDE SIGNALING PATHWAY FOR CANCER THERAPY
1) To determine which gene promoters are activated by BRG1 and/or BRM after reexpression in deficient NSCLC cell lines.  We have determined that 9 hours is the earliest time point for reexpression of BRG1 in the A427 cell line.  We had a proble
Sarcoma is a heterogeneous disease with at least 50 different subtypes. This genetic diversity makes the development of new targeted therapies particularly challenging. However, one consistent theme now emerging is that activation of the IGF-1R
Normal Tissue Complication Modeling for Radiotherapy
The goal of this proposal is to investigate the feasibility of treating ovarian epithelial carcinoma (OEC) with intelligent virus-mimetic nanogels (VM-nanogels). The VM nanogel has a core-shell type micelle-like structure. The core is construct
INTELLIGENT POLYMERIC NANOGEL TECHNOLOGY OVERCOMING DRUG RESISTANCE IN OVARIAN CANCERS
The purpose of this project is to study how key biochemical pathways interact in controlling the normal characteristics and functioning of cells in tissue of the the large and small intestine, and the alterations in these pathways and their int
Prostate cancer is the most common malignancy and the second highest cause of cancer mortality in American men. New prognostic and predictive biomarkers are urgently needed to better inform our treatment decisions. Recent studies have demonstra
CIRCULATING TUMOR CELL CAPTURE & ANALYSIS IN A MULTI-CENTERPROSTATE CANCER TRIAL
DESCRIPTION (provided by applicant): Experiments are proposed to investigate the interaction between two risk factors for drug abuse: prenatal stress and being female. It is hypothesized that prenatal stress alters the neural systems that respo
Drug Abuse: Sex differences in developmental and environmental influences
Child abuse and neglect are huge social problems affecting millions of infants, children, and adolescents in America. Several decades of research indicate that experiencing abuse or neglect is associated with substance abuse and a variety of ot
From Child Maltreatment To Adolescent Substance Abuse: Risks, Protective Factors
To pilot test a universal program developed to enhance family protective factors near the end of elementary school, thereby buffering children from the elevated risks of substance use and associated problems that will soon emerge in early adole
PILOT STUDY OF SIBLING PREVENTION PROGRAM
This project is being supported with funds from the American Recovery and Reinvestment Act, which may involve a reduction in the research aims and scope. If necessary, a revised abstract will be posted soon and this notice removed.  Consolidati
ARRA Malter Pin1 in Synaptic Plasticity and Translation
Regulatory RNAs are important mediators of gene expression in eukaryotic cells. BC RNAs, a neuronal subtype of regulatory RNAs, are translational repressors that have been implicated in the control of local protein synthesis at the synapse. On-
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO ,THE
(Project SAFE) (121-125). These studies designed and evaluated culturally relevant, minority-women-specific STI-clinic based interventions for inner city adolescent women with a history of abuse and STI. The interventions based upon the AIDS R
TRANSLATION OF INTERVENTIONS FOR RURAL MEXICAN-AMERICAN ADOLESCENT WOMEN
Opioid abuse and dependence continues to be a significant problem in the US; in particular, rates of non-medical use of prescription opioids have increased in the past several years. The main treatment approaches include detoxification followed
Dronabinol naltrexone treatment for opioid dependence
This research addresses the need for innovative bioreactor design. Bioreactors are laboratory systems that precisely control mechanical forces and environmental conditions on biologically changing tissues for periods of several hours to many da
BIOREACTORS FOR TISSUES EXPOSED TO HIGH FREQUENCY VIBRATION
The prevalence of fluorosis among the population is increasing yet we currently know very little about what causes fluorosis. We have previously demonstrated that fluoride elicits a cell stress response which in turn, activates genes to help th
THE ROLE OF ER-STRESS AND PH IN FLUOROSIS
Using live animal imaging, we have revealed that the bacterial pathogen Listeria grows inside the gallbladder. This bacterium normally replicates within cells, which permits it to invade many tissues, causing life threatening disease especially
Extracellular Replication of Listeria in Vivo
The pancreas secretes digestive enzymes and fluid that contains a lot of HCO3 that wash the enzymes to theintestine.                                                                               The HCO3  is needed to prevent premature activati
Molecular Mechanisms of HCO3- Secretion by Pancreatic Duct - ARRA Stimulus 2 Yr Resub
The overall goal of this proposal is to understand the contribution of metabolic, behavioral and diabetes-specific risk factors to the development of cardiovascular sub-clinical abnormalities in adolescents and young adults with T1D, as compare
Sub Clinical Cardiovascular Disease in Youth (SEARCH CVD)
Obesity is a risk factor for the development of cardiovascular disease, diabetes, and cancer. The emerging role of angiogenesis in regulating growth of adipose tissue is a subject of great interest and investigation. We have reported that Hepat
HGF Signaling in Adipose Tissue Growth and Metabolism
Existence of powerful nuclear reprogramming activities in egg cytoplasm has been unequivocally demonstrated by successful somatic cell nuclear cloning using terminally differentiated cell nuclei as donors. These reprogramming activities can ind
Histone proline isomerization and gene regulation
The proposed program of research will address conservative therapies for OAB and urge incontinence in men. We will plan a 2-stage, randomized clinical trial to examine the effectiveness of behavioral treatment, drug therapy, and combined behavi
COMBINED BEHAVIORAL AND DRUG TREATMENT OF OVERACTIVE BLADDER IN MEN
Hirschsprung disease, or aganglionic megacolon, is a congenital defect that affects 1 out of 5,000 live births and is characterized by a failure to form enteric nervous system (ENS) in a variable length of the hindgut. This potentially fatal co
HUMAN EMBRYONIC STEM CELL-DERIVED NEURAL CREST STEM CELLS AND HIRSCHSPRUNG DISEA
The specific aims of this Phase 1 of a 2-Phase program to design, manufacture, and operate a prototype 200MHz/38mm 'bench-top' NMR 'annulus' magnet (in Phase 2: 300MHz/43mm and 500MHz/43mm magnets) are four-fold: 1) Design, manufacture, and ope
Compact, Neon/Cryocooled NMR Magnets Assembled from Superconducting YBCO Annuli
A barrier to the effective delivery of cancer chemotherapy drugs is the transport of the toxic drug to specific tumor cells, ensuring high uptake of drug by cancer cells while avoiding noncancerous ones. One means of accomplishing this method i
Dendritic Block Copolymer Micelles as New Targeted Drug Delivery Systems
Different electric and magnetic field (E/MF) configurations have been applied for non-invasive imaging therapies and surgery (laser) for many years. Unlike their higher energy counterparts, the biological mechanisms underlying the effects of ex
Biophysical Response Factors to Weak Electric and Magnetic Fields
Development of wearable sensors for point-of-contact, near-real time monitoring of exposure to enviromental chemical species is critical to the success of studies of diverse populations. The demand for these sensors is driven by the yet unmet n
Wearable Organic Electric Film RFIR Sensor for monitorong Airborne Toxicants
Excessive exposure to manganese results in basal ganglia pathology and enhanced production of inflammatory mediators (cytokines, nitric oxide, prostaglandins) by activated glia in vitro. At present, there are no in vivo studies describing the
Role of inflammation in manganese neurotoxicity: molecular mechanisms
Formaldehyde is an important industrial chemical to which millions of workers are exposed worldwide.  Environmental exposures can also be significant as a result of off-gassing in new mobile homes and from combustion. The International Agency o
Biomarkers of Formaldehyde Exposure and Toxicity
The purpose of this grant is to study the regulation of the ocular surface immune response to desiccating stress.Sjögren’s syndrome causes profound dysfunction of the lacrimal functional unit (LFU) that results in decreased secretion of tear
Environmentally-Induced Ocular Surface Inflammation Mimicking Sjogren's
The overall goal of this proposal is to investigate the role of protein tyrosyl-sulfation in normal retinal function. The intermediate aims include the identification of retinal proteins that are sulfated by tyrosylprotein sulfotransferases and
RETINAL DEGENERATION CAUSED BY ALTERATIONS IN PROTEIN O-SULFATION
Two million people are visually impaired by glaucoma in the US. Glaucoma causes progressive dysfunction and death of retinal ganglion cells (RGCs) resulting in blindness. Our long-term goal is to prevent RGC death in the early stages of glaucom
RETINAL GANGLION CELL PLASTICITY IN GLAUCOMA
Glaucoma is the second leading cause of blindness in the United States. Understanding how retinal ganglion cell (RGC) susceptibility to degeneration is modulated by the major risk factor, elevation of intraocular pressure (IOP), as well as othe
NEURITIN:NOVEL RGC NEUROTROPHIC FACTOR AND POTENTIAL TARGET FOR GLAUCOMA THERAPY
The proper control of cell migration is critical for metazoan development. Directed migration requires secreted extracellular signals that act through cell surface receptors to guide the migrations of those cells. Secreted Wnt proteins are memb
Mechanisms of Wnt Signaling in Cell Polarity and Cell Migration
Circadian clocks are self-sustained biochemical oscillators that underlie daily rhythms of sleep/waking, metabolic activity, gene expression, and many other biological processes. Their properties include temperature compensation, a time constan
Structure of Circadian Clock Complexes From Cyanobacteria by Three Dimensional EM
The proposed research will further develop a new mass spectrometric technique to examine protein structure and dynamics via the attachment of residue specific noncovalent probes. The technique is referred to as selective noncovalent adduct prot
Probing Natively Disordered Proteins with Selective Noncovalent Adduct Protein Probing Mass Spectrometry (SNAPP-MS)
Revised Abstract Section TAK1 kinase is an indispensable intermediate in the intracellular signaling of innate immune responses.  TAK1 is activated by many of distinct factors including Toll-like receptor ligands, intracellular microorganism se
TAK1 Regulation of Reactive Oxygen Species and Inflammation
The Inferior Colliculus as a Site of Electrical Stimulation ARRA
Over the past few years several important oral pathogens have been fully or partially sequenced. These genetic sequences hold a tremendous amount of biological information and valuable data to be explored and analyzed. Microarray is one of the
COMPREHENSIVE TRANSCRIPTOME ANALYSIS FOR PORPHYROMONAS GINGIVALIS
Muscle wasting is common in advanced chronic kidney disease (CKD) and adversely affects morbidity and mortality.  In 2/3 of males with advanced CKD serum testosterone (TT) levels are reduced, and likely contributes to the wasting.  As TT in rel
Testosterone Replacement Therapy in Advanced Chronic Kidney Disease
Development and evaluation of biodegradeable neural electrodes.  Porvides summer research experience for two students in health related  scientific research.  The students will learn how to develop novel biodegradeable probe materials for enhan
Development and evaluation of biodegradeable neural electrodes
Grant Title: Activating liver carcinogens in yeast by expressing CYP450 polymorphisms. Abstract:  Exposure to carcinogens, including aflatoxin B1 (AFB1), benzo[a]pyrene (BaP), heterocyclic amines (HAs), poses a significant risk factor for liver
Activating liver carcinogens in yeast by expressing CYP450 polymorphisms
In the parent grant, we propose to develop a system where retinal neural circuits can be reproducibly designed on microelectronic arrays. Our project relies on optical tweezers, which we have used in a novel way to micromanipulate neurons isola
Designer Retinal Circuits:  Interfacing optical tweezers with an electronic device
Our research into the pathophysiology of presbyopia, the age-related loss of the eye's ability to focus on near objects, has found evidence in a monkey model that the aging ciliary muscle is restricted in accommodative movement by its posterio
ARRA Extra-lenticular aspects of accommodation and presbyopia
This award supported three college students to work in the laboratory over 11 weeks in the summer of 2009 and gain hands on experience at the bench so that they might consider a career in science.  During their time in the laboratory,  the stud
TARGETING THE CHOROID PLEXUS FOR DRUG TRANSLOCATION INTO CSF
, a powerful new technique for studying protein binding and conformations. This technique will enable the study of antibody-antigen binding for pathogenic bacteria; variation in antigens is currently one of the major obstacles to the developmen
ALGORITHMS AND SOFTWARE FOR DIFFICULT PROTEOMICS PROBLEMS
Children with special health care needs (CSHCN) make up 15% of all children and account for the majority of pediatric health expenditures. Parents of CSHCN experience greater work disruptions than other parents, largely due to episodic exacerba
Follow-Up Study: Paid Family Leave Insurnace/Families
DESCRIPTION (provided by applicant): Exploring the Import of Health-related Residential Mobility to Local Area Studies Description / Summary: Although most studies of place effects on health are ecological or multilevel analyses of cross-sectio
EXPLORING THE IMPORT OF HEALTH-RELATED RESIDENTIAL MOBILITY TO LOCAL AREA STUDIES
Trauma is the leading cause of death and disability in children. This project will design and test neuroprotective efficacy of mitochondria targeted antioxidants against neuronal death in TBI using state of art oxidative lipidomics and mass spe
Role of Cardiolipin Oxidation After Traumatic Brain Injury in Immature Rat
, as a drug carrier that can target and deliver a therapeutic agent to the injured vessel wall after cardiovascular interventions.  This new student will perform the in vitro studies of these nanoparticles using cell culture models.  These stud
NANOPARTICLES FOR TARGETING DRUG DELIVERY TO THE INJURED VASCULAR WALL
Hopkins Digestive Diseases Basic Research Development Center (DDBRDC) services 30 Hopkins PIs and has as its goal improving the research in gastroenterology done at JHUSOM. Due to the success of this Core Center we are overwhelmed in use of our
HOPKINS DIGESTIVE DISEASE BASIC RESEARCH DEVELOPMENT CENTER
CSDE's administrative supplement request is aimed at enhancing an emerging program of spatial demographic research at the University of Washington.  Supplement funds will be used to promote more spatial demography research through the pilot pro
Center for Studies in Demography and Ecology: Adminstrative Supplement
Administrative supplement for purposes of accelerating the tempo of research in several key areas as well as enhancing job creation and retention for investigators and support staff.
Research Methods for Cognitive Rehabilitation
The purpose of this proposal is to expand the capabilities of the Center for Experimental Neurorehabilitation Research Training (CENT) by adding a desktop scanning electron microscope (EM) capability to our micro imaging armamentarium.  The lab
CENTER FOR EXPERIMENTAL NEUROREHABILITATION TRAINING
The NCMRR Center at Children?s National Medical Center provides a broad array of services to medical rehabilitation researchers nationwide, including DNA (genotyping, sequencing), mRNA profiling, and proteomics assays, as well as database desig
Integrated Molecular core for Rehabilitation Medicine
Community Approaches to Cardiovascular Health: Pathways to Heart Health (CATCH-PATH) proposes to implement and evaluate a community-based participatory research (CBPR) intervention designed to reduce and ultimately eliminate disparities in card
HEP COMMUNITY APPROACHES TO CARDIOVASCULAR HEALTH: PATHWAYS TO HEART HEALTH
The administrative supplement aims to reduce Hepatitis B health disparities for medically underserved Korean Americans using CBPR approaches. Specifically, this supplement will enable us to strengthen and expand the community research infrastru
CBPR on Hepatitis B Intervention for Underserved Korean Americans
There is a documented need for palliative care training for practitioners of internal medicine and related subspecialties at the post-doctoral level. Our project's goal is to create palliative and end-of-life competency assessment tools to be u
HOSPICE Educational Program for the School of Medicine
Overweight and obesity are epidemic in the United States with over 2/3 of American adults having a body mass index of > 25 kg/m.2 Obesity and physical inactivity represent the second leading cause of preventable death nationally from cancer, ca
Nutrition, Exercise, and Weight Management Lifestyle Intervention (NEW Lifestyle)
. As part of the curriculum, we made 4 videotapes illustratingthe core teaching techniques that are part of the Oncotalk Teachprogram. These videos have been highly rated by the course participants.In our original proposal, we intended to creat
Training Oncology Faculty to Teach Communication Skills
Charles R. Drew University of Medicine and Science (Drew) proposes to continue and enhance its Drew National High School Student Summer Research Apprentice Program (NHSSSRAP). The main goal is to increase the number of underrepresented minority
DREW NATIONAL HIGH SCHOOL STUDENT SUMMER RESEARCH APPRENTICE PROGRAM
This is a supplement to our IMSD grant, which funds student research.  The supplement provides computers for a laboratory course and a flow cytometer that will be used in lab classes.  We also will hire a graduate assistant to help with evaluat
UNM Initiative to Maximize Student Diversity (IMSD)
For support to develop and/or implement a program as it relates to a category in one or more of the areas of education, information, training, technical assistance, coordination, or evaluation.
Gatekeepers and Roadblocks: Increasing URM Student Success in Science
with respect to the requirements of their next program. An array of individualized development activities will enhance the skills of each PREP scholar from their own starting points, (iii) foster later participation in translational research a
POST-BACCALAUREATE RESEARCH EDUCATION PROGRAM (PREP)
The IMSD Scholars Program in Brown University's Division of Biology and Medicine will significantly increase the number of underrepresented minority (URM) Ph.D. students trained for careers in basic biomedical and public health research. Effort
ADVANCING THE CULTURE OF PHD LEARNING AND SCHOLARSHIP IN BIOLOGY AND HEALTH SCIEN
The Clinical Research and Education for Career Development (CRECD) award  supplement will expand and enhance research development opportunities and mentoring for CRECD trained physician scientists at Meharry Medical College.
Clinical Research and Education for Career Development
The scope of the 'Clinical Research Education and Career Development (CRECD) in Minority Institutions' (R25RR17589) is to enhance the participation of minority health professionals in clinical and translational research that will have a signifi
CLINICAL RESEARCH EDUCATION AND CAREER DEVELOPMENT (CRECD) IN MINORITY INSTITUTIONS
The Multidisciplinary Clinical and Translational Research (MCTR) Certificate Program at MSM addresses the needs of a wide variety of trainees that are part of multidisciplinary research teams and benefit from MCTR training that is not currently
Renewal Application for Clinical Research Education and Career Development
Phase II. It provides additional funding for the creation of an online and published DVD curriculum based on the original documentary film and research project.
Serial Passage: AIDS, Race, and Culture Phase 2
The purpose of this project is to further disseminate inquiry-based laboratory exercises developed in our SEPA project by (a) adding a Program Coordinator who will double our capacity to conduct in-school visits for student use of the exercises
Phase I/II Partnership in Biomedical Discovery
The administrative supplement is for educational product development and is expanding a Virtual Clinical Research Center (VCRC) by accessing resources from the national network of Clinical Research Centers and translational laboratories as well
K-12 Virtual Clinical Research Center & Medical Ignorance Exploratorium: Phase I+
This Phase I and II application is designed to create and implement programs that better educate students regarding science concepts, the scientific inquiry process, and related careers. The Center of Excellence for Research, Teaching, and Lear
Research, Education, And Linking Science Careers: REAL Science Careers
The Spectrum initiative will pioneer a multi-pronged program that brings together K-12 teachers and students with biomedical scientists from multiple stages of the research career pthway to learn together about the biology behind women's health
Building Pathways to Biomedical Research Careers for Girls and Women Supplement
ARRA - UNC Framework Program in Global Health Administrative Supplement Funding from a Framework Supplement will support the full implementation of the online Certificate in Fall 2010 and will support instruction for the first three cohorts of
ARRA - UNC Framework Program in Global Health Administrative Supplement
A major challenge for the scientific community is to increase the participation of underrepresented minority students in biomedical research and subsequent leadership in the professoriate. For example, less than 10% of students in Case SOM biom
Case Postbaccalaureate Research Education Program (PREP)
Acute renal failure (ARF) is an increasingly common complication in hospitalized patients and is associated with extremely high mortality rates. The classical method of assessing renal function by measurement of serum creatinine is insensitive,
Inbred miniature swine provide a unique preclinical model for the study of transplantation immunity and tolerance. We have previously demonstrated that robust tolerance to MHC class l-mismatched renal allografts can be achieved following a shor
Tolerance to Vascularized Allografts in Miniswine
The global aim of the parent MERIT Award grant is to develop a molecular understanding of stem cell lineages and morphogenesis in mammalian skin and bring this research to a clinical setting. This important research centers around elucidating t
Cell adhesion and cytoskeletal dynamics in the skin
The Multiethnic Cohort (MEC) Study was designed to prospectively investigate the relationship of diet an other lifestyle factors to cancer risk in five ethnic groups (African Americans, Japanese Americans, Latinos Native Hawaiians and Caucasian
Multiethnic Cohort Study of Diet and Cancer
A request for an administrative supplement under the American Recovery and Reinvestment Act of 2009 willl allow for hiring of a new personnel as well as retention of existing fellows.
Diseases and suffering caused by reactivations of latent Herpes Simplex Viruses (HSV) remain a major medical problem notwithstanding effective attenuation of disease by currently available antiviral drugs. The major problem facing development o
DISSECTION OF THE FUNCTIONS OF HERPES SIMPLEX VIRUS ICPO
Notice Number - NOT-OD-09-058 Notice Title: NIH Announces the Availability of Recovery Act Funds for Competitive Renewal Applications. Type 2 diabetes is characterized by impaired insulin action in tissues such as muscle, liver, and adipose tis
Glucose Transporter Regulation in Obesity and Diabetes
The machinery responsible for making proteins (e.g. ribosomal RNA, ribosomal proteins, translation factors, and tRNAs) is central to growth and development of all organisms, and the control of its synthesis has been a central issue in molecular
ARRA Mechanism, Activation, and Regulation of rRNA Transcription
DESCRIPTION (provided by applicant): Organelle movement is a hallmark of cell division and cellular differentiation. In every cell-type, the localization, number and morphology of each type of organelle is modified to achieve specific cellular
REGULATION OF MYOSIN V INTERACTION WITH CARGO
We propose an Administrative Supplement, under the Recovery Act (NOT-OD-09-056), to parent grant, NIH R37 HD025594, 'Cell Motility and Cell Interactions During Neurulation'. The work proposed here will greatly accelerate and extend the progress
Cell Motility and Cell Interactions During Neurulation
Since the passage of landmark welfare reform legislation in 1996, considerable attention has been paid to the impact of the time-limited benefits, sanctions, and work requirements of the law, as well as its overall impact, on economic and demog
RESEARCH ON THE EFFECTS OF THE U.S. WELFARE SYSTEM ON THE LOW INCOME POPULATION
The present Administrative Supplement will help purchase equipment and/or retain personnel to accelerate progress toward understanding the flexibility of neural circuits that control hand and finger movements. Understanding how neurons of the b
CORTICAL ACTIVITY DURING INDIVIDUATED MOVEMENTS
Epilepsy affects 1-2% of the population. Half of all new cases arise in infancy through early adolescence. Seizure outcomes are highly varied. Epilepsy can be a life-long intractable disorder or may resolve after only a few seizures. Many indiv
Long-Term Outcomes of Childhood-Onset Epilepsy
This supplement proposal investigates a new compound that can block the white blood cells that cause Graft vs. Host Disease (GVHD) and the proteins that cause the symptoms associated with GVHD.  Experiments are proposed in animal models to test
Inhibition of IKKb to treat lethal Graft-vs.-Host Disease
An Integrated Room Temperature Crystal Characterization System Square One Systems Design, Inc. Summary: The goal of Square One Systems Design?s STTR Phase II development effort is the creation of a flexible automated workcell-- the Universal Mi
A UNIVERSAL MICROMANIPULATION ROBOT FOR CRYSTALLOGRAPHY
and 3) demonstrated (n=32) a significant increase in knowledge pre/post test, (p<0.001), and statistically significant increase in attitudes, self-efficacy, and intended behavior (p<0.05). Phase II is completing our computer-based training cur
MEDICAL STUDENT EDUCATION ON ALCOHOL ABUSE AND DEPENDENCE
AMERICAN LIFE SCIENCE PHARMACEUTICALS, INC.
Grant Title: Development of protease inhibitor drugs to treat Alzheimer's disease.  The ARRA grant allows a postdoctoral hire to synthesize inhibitor drugs that may lead to potential Alzheimer's disease drugs.
Development of protease inhibitor drugs to treat Alzheimer's disease
The objective is to design, build, and clinically assess ParkinTune, an advanced wireless movement disorder technology to augment stimulation programming (tuning) involved in deep brain stimulation (DBS) procedures for Parkinson?s Disease (PD).
ParkinTune: Automated PD Motor Symptom Assessment for DBS Programming
This overall parent project aims to develop a new, highly sensitive, mutation scanning technology for the molecular analysis of cancer. While broadly applicable in oncology, the initial commercial product which is the focus of the parent Phase
ADVANCED TECHNOLOGY FOR ASSAYING CANCER-DRUG RESISTANCE
This award provides additional funding for 5R44HL081789-03.  This additional funding is provided under the American Recovery and Reinvestment Act of 2009 (ARRA) and is
Nanoparticle Generator for Animal Inhalation Experiments
The development of drugs aimed at controlling eating disorders represents a major target of the pharmaceutical industry. The long term goal of the parent project is to develop tools for high throughput testing of drug compounds from combinator
Screening Method for GPCRs Related to Appetite
Project Summary Research is proposed to address PA-04-119 Biodefense and Emerging Infectious Disease Research Opportunities. WNV is a NIAID Category B priority pathogen. The introduction of a single WNV strain at a relatively well characterized
MECHANISMS OF WEST NILE VIRUS SELECTION AND STRAIN DISPLACEMENT
Cell death (apoptosis) is implicated in the infectious life cycle of a variety of pathogens, such as the malaria parasite and the West Nile virus, in mosquitoes.  Understanding the mechanism of cell death response will help us to develop strate
Systematic Analysis of cell Death Regulation in Mosquitoes
Retinoic acid (RA) is a critical signaling molecule that regulates cell division and apoptosis. Alterations in RA homeostasis have been linked to several important diseases such as cancer, obesity, Alzheimers disease and type 2 diabetes as well
Effects of Xenobiotics on CYP26 Activity and Retinoic Acid Homeostasis
AMERICAN FOUNDATION FOR BIOLOGICAL RESEARCH
To purchase a new image analyzer for my laboratory on NIH parent grant# 5R01AI063480-05
A gene map for Biomphalaria glabrata, a S. mansoni host
Myelodysplastic syndromes (MDS) are characterized by defective blood formation and high risk for leukemia development and primarily occur in individuals over the age of 65 years old. New strategies of treatment are needed for age-related diseas
Modulation of T cell Homeostasis in Myelodysplastic Syndrome (MDS)
The Specific Aim of this project is: to examine effects of hyperglycemia, hyperinsulinemia and combined hyperglycemia and hyperinsulinemia on various parameters of blood coagulation in C-peptide negative patients with type 1 diabetes mellitus (
Hyperglycemia and Hyperinsulinemia Induced Procoagulant State
The incidence of type 2 diabete is increasing at an alarming rate both nationally and worldwide with more than 1 million new cases per year diagnosed in the US alone. Vitamin D and calcium are two nutritional factors that have been suspected as
Vitamin D and Calcium Homeostatis in Relation to Type 2 Diabetes
This project will accelerate the tempo and achievement of scientific research about undergraduate science education, with specific attention to an enriched, federally-supported intervention aimed at increasing the number of undergraduates from
MARCU STAR In action In Contrasting University Settings
The goal of this Supplement Award is to enable the PI to pay for a post-doc to speed up some of the experiments proposed under the aims in the PI's grant entitled: “Hypoxia-induced Endothelial Barrier Dysfunction”.  Under this application w
The main aim of this grant  (administrative supplement)  is to adquire equipments needed to develop the objectives of the parent grant.  This grant is related to all Aims described in the Parent Grant that will use leptin peptide receptor antag
Involvement of leptin and interleukin-1 signaling in mammary cancer progression
I025, a novel uncultivable bacteria group, has been associated with periodontal disease, which affects 18% of the adult population in the industrialized world. Neither the natural reservoir nor the complete diversity of this group is known. I02
ENVIRONMENTAL UNCULTIVABLE BACTERIA MODEL FOR UNDERSTANDING HUMAN PERIODONTITIS
This supplement will accelerate the pace of research that examines the physiological and genetic responses to osmotic stress in yeast.  This ARRA supplement provides for increased employment of a research assistant from part-time (30 hr/wk) to
Physiology of Osmotic Stress in Saccharmyces cerevisiae Supplement
The nanoscale reading of DNA sequences is envisioned to take place at a nanogap defined by a pair of nanoelectrode tips as a DNA molecule moves through the gate base by base. The rationale is that the four different nucleotide bases and their v
MULTISCALE SIMULATIONS OF TRANSPORT IN DNA AND DNA-CARBON NANOTUBE SYSTEMS
This is a supplement to the principal investigator's SC3 grant. This project will provide information regarding the role of protease-activated receptors in the regulation of the endothelium, which plays an important role in vascular tone.  Endo
The Role of Protease-Activated Receptors in the Regulation of eNOS
DESCRIPTION (provided by applicant): Celiac disease is an autoimmune digestive disorder in which intestinal lesions develop in genetically susceptible individuals in response to the ingestion of specific cereal seed storage proteins. The only t
TILLING WHEAT FOR REDUCED CELIAC DISEASE CAUSING PROTEINS
Nontypeable Haemophilus influenzae (NTHi) commonly colonize the mucosal surfaces of the human upper respiratory tract.  For the most part, this species resides in that environment in a benign (symbiotic?) relationship with the human host.  With
H. influenzae: Role of Sialic Acid in Virulence
The long term goal of this project is to elucidate the roles protein arginine methylation in Trypanosoma brucei gene expression, particularly at the RNA level. These studies will greatly increase our understanding of gene regulation in a medica
ARRA: Protein Arginine Methylation in Trypanosomes
.  In the studies of parent project, we found a significant activity of NF-kB in the induction of energy expenditure.  The activity found in the NF-kB transgenic mice with gain-of-function was so strong that the mice were protected from insulin
Intergration of IKK and JNK signals in Insulin Resistance
BK-type calcium-activated potassium channels serve as cytoplasmic Ca2+ detectors that can rapidly respond to and modulate transmembrane voltage. These channels are critical in controlling action potential firing in neurons as well as smooth mus
Structure and Function of Potassium Channels
ENVIRONMENTAL QUALITY, OKLAHOMA DEPARTMENT OF
In 2004, the State of Oklahoma established a local trust, the Lead Impacted Communities Relocation Assistance (LICRA) Trust to oversee the relocation of families with children less than seven years old, from the area surrounding the towns of Pi
Tar Creek Buyout Oklahoma Plan-American Recovery and Reinvestment Act 2009
This award will fund portions of the Central City/Clear Creek Superfund Site Operable Unit 4 remedial action, specifically the Tributary Sediment Reduction Components, Repository and the Mine Water Conveyance projects.  These actions will resul
We propose to continue an interdepartmental training program for Drug Discovery Training in Age-Related Disorders - a program devoted to providing predoctoral andpostdoctoral scholars with rigorous interdisciplinary training in drug discovery a
Drug Discovery Training in Age-Related Disorders
SEATTLE INSTITUTE FOR BIOMEDICAL AND CLINICAL RESEARCH
Project objective:  This project will perform annual cognitive evaluations on subjects previously enrolled in the Alzheimer's Disease Anti-Inflammatory Protection Trial (ADAPT).  The purpose of these evaluations is to extend observations on the
Prevention of Alzheimer Dementia and Cognitive Decline
As life expectancy in the United States continues to rise, the maintenance of physical independence among older Americans has emerged as a major clinical and public health priority. Efficient and reliable locomotion, or the ability to move with
CLEAN WATER FINANCE AGENCY, RHODE ISLAND
This agreement provides funding under the ARRA of 2009 to the State of Rhode Island to capitalize its revolving loan fund for the financing of construction of 16 wastewater treatment projects:  sewer cleaning (2); wastewater treatment facility
This agreement provides funding under the ARRA of 2009 to the State of Vermont to capitalize its revolving loan fund for the financing of construction of wastewater treatment facilities and associated infrastructure, green infrastructure, nonpo
The goal of this UCLA-Fogarty Program is to collaborate with Mexican faculty and experts in the development of two virtual education courses, a Chemical Policy and Risk Assessment and Biological Exposure Assessment to address immediate needs to
UCLA - MEXICO/COLOMBIA COLLABORATIVE TRAINING AND RESEARCH PROGRAM
ln 3-month paid research experiences, over two summers, 4 talented undergraduate engineering and computer science students will be recruited to contribute in a substantial way to the progress of sub-aims of my parent New lnnovator (DP2) Award;
Novel TIRF Microscopy for Analyzing Trafficking and Signaling at the Cell Cortex
Complicated Grief in Older Adults: The Physiology of Emotion Regulation - The supplement application supports the parent project by increasing the recruitment of diverse older adults in two unique ways:            Supplemental Aim 1: recruiting
COMPLICATED GRIEF IN OLDER ADULTS: PHYSIOLOGICAL SUBSTRATES OF EMOTION REGULATION
PERCEPTIONS OF SOCIAL USEFULNESS/VALUE AS PREDICTORS OF HEALTH IN OLDER ADULTS   The overall purpose of this project is to assess older adults' experience of both burdens and benefits as volunteers in a high-intensity volunteer program, the Exp
PERCEPTIONS OF SOCIAL USEFULNESS/VALUE AS PREDICTORS OF HEALTH IN OLDER ADULTS
'Statement of Purpose:  To incorporate visual aids into science lectures developed by post-docs for undergraduate courses
Houston Education And Research Training Program for Post-docs
HIV AND HEPATITIS B COINFECTION HEPATITIS B GENOTYPE RESISTANCE AND OUTCOMES   Explore HBV outcomes in HIV/HBV coinfected individuals including the prevalence of HBV infection and HBV genotypes (SA1), the association between HBV genotype with H
HIV AND HEPATITIS B COINFECTION: HEPATITIS B GENOTYPE, RESISTANCE AND OUTCOMES
Core C, the Cell Culture and Animal Models Core, is an integrated, dedicated, essential component of the Program, which will provide materials and services to all four Projects of the Program. This Core supports the Projects by providing specia
DNA Repair in Cancer Biology and Therapy
This program project examines the structure, biosynthesis, and roles of carbohydrates in cell-cell interaction.  The proposed projects were borne-out from our strong collaborative research activities in the previous funding period.  This progra
Carbohydrate-Dependent Adhesion in Normal and Tumor Cells
This proposal requests support to continue development of a Center of Biomedical Research Excellence in Protein Structure and Function (COBRE-PSF) at the University of Kansas. Our Center was established in October 2002, and includes participant
Diabetes and Endcrinology Research Center (DERC) - During the past 20 years, the DERC, with its Core Laboratories, Enrichment Program and support for Pilot and Feasibility (P&F) studies, has played a major role in fostering expansion in the sco
Diabetes and Endcrinology Research Center (DERC)
The human brain consists of approximately 100 billion neurons, which form over 100 trillion synapses with specific targets. How neurons find the correct targets and how the correct wiring of the brain influences behavior are central questions,
Synaptic Target Selection in the Thermotaxis Neural Circuit of C. elegans
For this supplement, I plan to recruit several summer researchers, for summer 2009 and summer 2010, to accelerate the pace of discovery and to provide research opportunities for high school and undergraduate students, as well as a science educa
Activation of Insect Immunity by Gram-Negative Bacteria
The purpose of this administrative supplement is to obtain salary and a small supply budget for a college student summer research internship.  The benefits to this internship are twofold, including (1) acquiring additional staff to expedite a p
Memory T cell subsets and pulmonary immunity
The PROMISSE Study (Predictors of Pregnancy Outcome: bioMarkers In antiphospholipid antibody Syndrome Systemic lupus Erythematosus) is a multi-center, prospective observational study designed to characterize the mechanisms of antiphospholipid (
Predictors of Pregnancy Outcome in SLE and APS
Epithelial ovarian cancer (EOC) is the fourth leading cause of cancer-related death in women in the United States and is the leading cause of gynecologic cancer death. A major limitation in the treatment of ovarian cancer is the widespread deve
The overall objective of this research proposal is to define the multifaceted role of the MUC4 mucin in the pathogenesis of pancreatic cancer (PC). During past funding cycles, we have made considerable progress, beginning with the cloning of th
The overall goal of the parent RO1 grant is to develop, validate and apply DSC (dynamic susceptibility contrast) MRI methods to monitor brain tumor angiogenesis (new vessel formation) and assist with development and optimization of both new and
MRI Contrast Agent Methods of Assessing Tumor Angiogenesis
The parent grant investigates how Cbl family ubiquitin ligase-dependent and ubiquitin-mediated negative regulation negative regulation of EGF receptor is effected at the biochemical and cellular levels and to what extent this physiological nega
Molecular Control of EGF Receptor down-Regulation
Abstract The SenseLab suite of 8 interoperable databases is aimed at supporting our research on a model system for brain organization, the olfactory bulb, and at sharing these and related resources with the neuroscience and neuroinformatics com
Sense Lab: Integration of Multidisciplinary Sensory Data
Project Summary: During development, sensory innervation to taste buds is tightly regulated by the actions of the neurotrophin, brain-derived neurotrophic factor (BDNF). BDNF is expressed in gustatory epithelium and determines whether gustatory
Neurotrophin regulation of taste system development
Craniofacial malformations are among the most common birth defects in children and lead to substantial morbidity and mortality for these infants. Despite the severity of the illness, little is known about the molecular mechanisms that are neces
Characterization and cloning of X. tropicalis Craniofacial Mutants
. We propose to study this hypothesis in a population of KTX recipients with the following specific aims: 1. Determine the rate and direction of CVD progression and its association with CVD events and traditional CVD risk factors; 2. Correlate
Vascular Risk after kidney Transplantation
Heart & Circulatory System Diseases & Disorders
is due partially to high flow rates that stimulate K+ secretion in the distal nephron. However, the cellular mechanisms for flow-stimulated K+ secretion have never been understood. In this proposal, we plan to address this question using novel
Role of BK-B1 in Flow-Dependent K+ Secretion in the CNT
Summary of the parent grant: The parent grant (R01 EB006200-04) proposed the development of a Continuous-Imaging HT Screening Instrument that would allow a 10-fold speed increase over the current Beckman Coulter IC-100 instrument. This increase
Continuous-Imaging HT Screening Instrument (Student Supplement)
High resolution structural, functional and spectroscopic magnetic resonance (MR) imagings of the brain are powerful technologies for the study of epilepsy. Image-guided surgical resection has proven to be an effective treatment for many cases o
BioImaging and intervention in localization-related epilepsy
The role of CYP2S1 in asthma  Asthma is a condition caused by allergic airway inflammation, or 'airway hyperresponsiveness', in which the patient periodically experiences paroxysms of wheezing, labored breathing and coughing, due to narrowing a
FUNCTION AND REGULATION OF HUMAN CYTOCHROME P4502S1
This was a request for supplemental funding for two undergraduate students to continue to work on EY014701 and its supplement. ?GABAc Receptors and Mouse Retinal Ganglion Cell Responses?. The focus of the research in this grant is the character
GABAc Receptors & Mouse Retinal Ganglion Cell Responses
. The project involved evaluation of the contribution of PITX2 and several other ocular genes in Axenfeld-Rieger syndrome and other eye disorders. Expected outcomes included identification of novel gene mutations, identification of novel varian
Molecular Mechanisms of Axenfeld-Rieger Syndrome
The long term goals of this project are to understand how misfolded RNAs are recognized and handled within cells and to investigate how RNA misfolding impacts cell function. Our focus is on the Ro autoantigen, an RNA-binding protein that is a m
RNA Quality Control and Environmental Stress
Reversible protein phosphorylation is one of the most common mechanisms for regulating cell behavior in eukaryotes. Genome sequencing efforts have uncovered hundreds of new predicted protein kinases. For most, we have little insight into their
Prteome-wide analysis of Kinase Phosphrylation specificity in yeast
The Na-K-Cl cotransporter (NKCC) is a plasma membrane transport protein that plays a central role in cellular homeostasis. In non-polarized cells including neurons the NKCC1 isoform is involved in regulation of intracellular chloride and cell v
Molecular Physiology of the Na-K-CI Cotranspoter
This Administrative Supplement to R01GM062631 aims to characterize in detail the molecular interactions between the TPR domain of the telomerase regulatory protein Est1 and telomerase RNA, based on our recent identification of multiple Est1 ort
Analysis of telomerase reverse transcriptase
This award is an administrative supplement to R01 GM077560 (Mechanism of ion channel modulation by ligands) which supports the hiring of one postdoctoral fellow, as well as the acquisition of equipment needed to speed up the research being done
Mechanism of Ion Channel Modulation by Ligands
The primary specific aim of our parent grant is “to determine the effects of low glycemic load diets on insulin, carbohydrate, and fat metabolism in obese, pregnant women stratified by visceral fat thickness.”  We hypothesize that a low gly
Diet Glycemic Load & Metabolism in Obese Pregnant Women
The aims of this proposal for supplementary funding are to complete the sequencing and annotation of four chromosomes – the mouse, rhesus, and bull Y chromosomes and the chicken Z chromosome – within two years.  These chromosomes represent
This Administrative Supplement will focus on the studies proposed in Specific Aim 3 of the parent grant: Specific Aim 3, To Demonstrate that COMBINED mechanical stretch and moderate hyperoxia increases alveolar type II epithelial cell apoptosis
Stretch and Hyperoxia in Ventilator-induced Lung Injury
The parent award, HL 084007 'Computational Approach to Ligand Discovery for LPA GPCR and PPAR', includes three specific aims that collectively address a single fundamental question. Namely, what structural characteristics confer selective agoni
Acute kidney injury (AKI) is common in patients undergoing cardiac surgery.  Even small increases in serum creatinine portend an increased risk of short-term and long-term death.  Serum creatinine, the traditional marker of renal function, only
Novel Biomarkers in Cardiac Surgery to Detect Acute Kidney Injury
The role of microRNAs in the Erythropoietic Stress Response.  In  aim 1, we will Investigate whether candidate erythroid miRNAs are differentially expressed in erythroid progenitors of mouse models of erythropoietic stress. In aim 2, we wukk in
Molecular Analysis of the Erythropoietic Stress Response in Vivo
INVESTIGATE STABILITY OF RNA INTERFERENCE IN HUMAN LYMPHOCYTES  Our overall hypothesis is that RNA interference (RNAi) can be developed to reduce specific gene expression over long-term without toxic effects in human lymphocytes. RNAi using siR
INVESTIGATE STABILITY OF RNA INTERFERENCE IN HUMAN LYMPHOCYTES
The objective of the parent proposal is to elucidate the mechanisms whereby scleroderma increases myocardial inflammation and fibrosis, which then results in myocardial dysfunction.  Matrix instability in scleroderma increases oxidative stress
Inflammation, Fibrosis and Myocardial Funcation in Schleroderma
Several lines of evidence suggest amino acid neurotransmitter system abnormalities contribute to the neurobiology of depression. In humans, there is clear evidence of altered amino acid neurotransmitter function in depressed individuals. Most n
13 C measurement of GABA Synthesis in Depresion
mouse model that our lab has developed.  He conducted a series of three separate behavioral tests on mice under the direct supervision of the PI and Dr. Xuqi Chen in our lab.  He measured group differences in behavior, analyzed results using N
SEX CHROMOSOME EFFECTS ON NEURAL DEVELOPMENT
Sp1, Kappa-B Enhancers and Transcription in Neurons: The parent grant is devoted to explaining the unique ways in which CNS neurons regulate and utilize the transcription factors NF?B and Sp1.  Despite a large interest in the potential roles fo
Sp1, Kappa-B Enhancers and Transcription in Neurons - Summer Student Program
This is an administrative supplement to an RO1 grant which focuses on the generation of genetic and genomic resources for the vervet monkey (Chlorocebus aethiops), also known as the African green monkey. The supplement will accelerate the rate
INTEGRATED GENETIC AND GENOMIC RESOURCES FOR A MODEL SYSTEM
Upon activation by antigen, B cells undergo antibody class (isotype) switching, changing from expression of IgM to expression of IgG, IgA or IgE, while maintaining specificity for the same antigen. Since the isotype determines the effector func
Molecular Basis of Immunoglobulin Heavy Chain Switch
Description of overall purpose.  The overall purpose of the administrative supplement grant is to increase the scientific value of its parent grant (R15 EB009535-01) by involving 3 additional undergraduates and 1 new high school teacher in our
Better, Faster Live-Cell Imaging:  Motion-Enhanced DIC (Medic) with Flourescence
This award is to provide support for hiring of a graduate assistant to help speed the identification of novel CB2 cannabinoid agonists as candidate therapeutics for the devastating, neurodegenerative disease amyotrophic lateral sclerosis (ALS).
Selective CB2 Cannabinoid Agonists as Candidate Therapeutics for ALS
T. pallidum strain (courtesy of Sheila Lukehart, Seattle, WA).  She is working with postdoctoral students in the Fikrig lab to learn molecular biology techniques (cDNA, RT- and qPCR) in this context to assess for infection. Preliminary finding
Tissue Specific Borrelia Gene Expression
to retain an exceptional postdoctoral fellow. These funds are supporting research that is within the general scope of the specific aims of my grant. Current studies focus on Aim 2 and how various forms of use-dependent synaptic odulation inter
Short-Term Synaptic Plasticity in the CNS
Fund a full time police officer position to enforce state and local laws.
THE COPS HIRING PROGRAM PROVIDES FUNDING DIRECTLY TO LAW ENFORCEMENT, TO HIRE, REHIRE, OR MAINTAIN CAREER OFFICERS  IN AN EFFORT TO CREATE AND PRESERVE LAW ENFORCMENT JOBS AND TO  INCREASE THEIR COMMUNITY POLICE  CAPACITY AND AND CRIME PREVENTI
The COPS Hiring Rehiring Program (CHRP) provides funding directly to law enforcement agencies to hire and/or rehire career law enforcement officers in an effort to create and preserve jobs, and to increase their community policing capacity and
Cops hiring recovery program grant for three officers
The CHRP provideds funding directly to law enforcement in an effort to save or create jobs.
The CHRP provides funding directly to law enforcement agencies to hire officers in an effort to create and preserve jobs, and to increase their community policing capacity and crime prevention efforts.
To hire law enforcement  officers.  The award  provided salary and benefits to  three (3) officers for first three (3)years of  service in our community  policing  efforts.
The COPS Hiring Recovery Program (CHRP) provides funding directly to law enforcement agencies to hireand/or rehire career law enforcement officers in an effort to ceate and preserve jobs, and to increase their community policing and crime preve
CHRP provides funding directly to law enforcement agencies to hireand/or rehire career law enforcement officers in an effort to create and preserve jobs, and to increase their community policing capacity and crime prevention efforts.
The COPS Hiring Recovery Progam (CHRP) provides funding direclty to Law Enforcement Agencies to hire and/or rehire career Law Enforcement Officers in an effort to create and preserve jobs, and to increase their community policing capacity and c
The COPS Hiring Recovery Program (CHRP) provides funding directly to law enforcement agencies to hire and / or rehire career law enforcement officers in an effort to creat and preserve jobs, and to increase their community policing capacity and
Chippewa Cree COPS Hiring Recovery Program provides funding directly to law enforcement agency's to hire and/or rehire career law enforcement officers in an effort to create and preserve jobs, and to increase their community policing capacity a
The COPS Hiring Recovery Program (CHRP) provided direct funding to law enforcement agencies to hire and/or rehire career law enforcement officers in an effort to create and preserve jobs, and to increase their community policing capacity and cr
The COPS Hiring Recovery Program (CHRP) provides funding directly to law enforcement agencies to hire and/or rehire career law enforcement officers in an effort to create and preserve jobs, and increase their community policing capacity and cri
The COPS Hiring  Recovery Program (CHRP) provides funding directly to law enforcment agencies to hire and /or rehire career law enfoecement officers in an effort to create an preserve jobs, and to increase their community policin capacity and c
The COPS Hiring Recovery Program (CHRO) provides funding directly to law enforcement agencies to hire and/or rehire career law enforcement officers
Th COPS Hiring Recovery Program (CHRP) provides funding directly to law enforcement agencies to hire and/or rehire career law enforcement officers in an effort to create and preserve jobs, and to increse their community policing capacity and cr
COPS CHRP provides funding directly to law enforcement agencies to hire and/or rehire career law enforcement officers in an effort to create and preserve jobs, and to increase their community policing capacity and crime prevention efforts.  The
COP Hiring Recovery Program (CHRP) provides funding directly to law enforcement agencies to hire/rehire career law enforcement officers in an effort to create and preserve jobs, and to increase their community policing capacity and crime preven
The COPS Hiring Recovery Program (CHRP) provides funding directly to law enforcment agencies to hire and/or rehire career law enforcment officers in an effort to create and preserve jobs, and to increase their community policing capacity and cr
The COPS Hiring Recovery Program (CHRP) provides funding directly to law enforcement agencies to hire career law enforcement officers in an effort to create and preserve jobs, and to increase their community policing capacity and crime preventi
The Cops Hiring Recovery Program provides funding directly to law enforcement agencies to hire or rehire career law enforcement.
'The Cops Hiring Recovery Program provides funding directly to law enforcement agencies to hire and/or rehire career law enforcement officers in an effort to create and preserve jobs, and to increase their community policing capacity and crime
The Cops Hiring Recovery Program provides funding directly to law enforcement agencies for the hire and rehire of career officers.
The COPS Hiring Recovery Program (CHRP)provides funding directly to law enforcement aggencies to hire and/or rehire career law enforcement officers.
The COPS Hiring Recovery Program (CHRP) provides funding directly to law enforcement agancies to hire and/or rehire career law enforcement officers in an affort to create ans preserv jobs, and to increase their community policing capacity and c
RICHMOND REDEVELOPMENT AND HOUSING AUTHORITY
The COPS hiring recovery program (CHRP) provides funding directly to law enforcement agencies to hire and or rehire career law enforcement officers in an effort to create and preserve jobs, and to increase their community policing capacity and
The COPS Hiring Recovery Program (CHRP) provides funding directly to law enforcement agencies to hire and/or rehire career law enforcement officers in an effort to create and preserve jobs, and increase their community policing capacity and pri
Yakima Police Department, 200 S. 3rd Street
The COPS Hiring recovery program provides funding directly to law enforcement agencies to hire and/or rehire career law enforcement officers in an effort to create and preserve, and to increase their community policing capacity and crime preven
The COPS Hiring Recovery Program (CHRP) provides funding directly to law enforcement agencies to hire and/or rehire career law enforcement officers in an effort to create or preserve jobs, increase their community policing capacity and crime pr
The COPS Hiring Recovery Program (CHRP) provides funding directly to law enforcement agencies to hire and/or rehire caree law enforcement officers in an effort to create and preserve jobs, and to increase their community policing capacity and c
VIRGINIA CENTER FOR POLICING INNOVATION, THE
The primary objective of the award through the COPS Office is to provide financial assistance to VCPI to carry out the public purpose of providing quality, cost-effective online training for the direct benefit of CHRP grantees through the CHRP
Recovery Act Edward Byrne Memorial Justice Assistance Grant (JAG): The City & County of San Francisco will apply funds to four priority areas: (1) Prosecution and court programs (2) Prevention and education programs (3) Corrections and communit
BJA FY09 Recovery Act Edward Byrne Memeorial Justice Assistance Grant Program Local Solicitation
We will enhance community policing by deploying more officers in problem area communities and address quality of life concerns on an overtime basis. We will continue to seek training for our front line officers as well as supervisors. We will p
purpose is to partner with County agencies to provide funds for items that are not budgeted through operating funds.   Each agency made a request deemed essential in improving the overall efficiency of their operations.  The monies have been a
Baltimore City's JAG Recovery Program - Creates 8 fulltime job positions, 10 part-time job position salaries, contracts with technology vendors and crime prevention partners.
The Lyon County Sheriff's Office Street Enforcement Team was developed to maintain proactive law enforcement against street crime, narcotic sales, burglaries, graffiti, criminal gangs, sex offenders and specific traffic problem areas. The prima
Purchase body armor, shotguns, and video equipment.
FY  2009 Recovery Act Justice Assistance Grant Programs
A Biotechnology Training Program in Biomedical Science and Engineering To Educate and To Train the Next Generation of  Scientists and Engineers for Leadership Roles in Multidisciplinary Biotechnology Research
BIOTECHNOLOGY TRAINING IN BIOMEDICAL SCIENCES
Specific Aims and Measurable Objectives: All science undergraduates are considered pre-MARC U*STAR Trainees. We intend to deepen the pool of freshman and sophomore students who attain honors level of academic achievement and thus are eligible t
Undergraduate Student Training in Academic Research
Supplement-Expand NCI-supported Community Outreach Capacity through Community Health Educators (CHE) of the National Outreach Network. The AR-CCN, partnering with NCI?s National Outreach Network (NON), seeks to be a catalyst for mobilizing a st
Arkansas Cancer Community Network (AR-CCN) Summer Research Internship Program
BRAIN BLADDER INTERACTIONS IN IC/PBS  Interstitial cystitis/painful bladder syndrome (IC/PBS) is a common chronic bladder syndrome characterized by bladder pain and discomfort (urgency) and increased frequency of urination. It is part of a larg
Title: Community-Based HIV VCT: South Africa NOT-OD-09-058: Description: NIH Announces the Availability of recovery Act Funds for Competitive Revision Applications The protective effect of-male circumcision on HIV acquisition may be due to impr
We are analyzing existing longitudinal MRI data previously obtained on prodromal patients and controls at 3 of the 8 U01 sites - UCLA, Yale, and the University of North Carolina - with the goals of enhancing prospective prediction of psychosi
1/8-PREDICTORS AND MECHANISMS OF CONVERSION TO PSYCHOSIS
Rehabilitate Runway - 04/22.  Design and implementation of the repair of cracks in the asphalt runway pavement surface; installation of pavement sealer/rejuvenator for the promotion of airport development and the continued maintenace of a viabl
Resurfacing Park Heights Avenue from Northern Parkway to Garrison Boulevard
Executive and Legislative Offices, Combined
Fairbanks International Airport Security Access Control Improvements
Huslia Airport Improvements. The project consists of resurfacing the runway and taxiway; rehabilitating embankment areas; replacing a lighted wind cone and segmented circle; and relocating threshold lights and Runway End Indicator Lights.
Repair and stabilize the runway embankment, taxiway and apron to correct areas that have experienced serious settlement, slope failures and erosion.
Airport Development-Security Upgrades (CCTV, Security Fencing and Access Control)for Tucson International Airport
The project is for Airport development, specifically, the realignment and reconstruct of the taxiway and the rehabilitation of the runway.  The project will enhance safety, protect the federal investment and increase the useful life of the pave
The rehabilitation of the General Aviation Apron at the Aspen-Pitkin County Airport completes a phased airport devlopment of the existing infrastructure on the entire east half of the airport.  The portion of apron that is being reconstructed c
Aspen Pitkin County Airport Reconstruct General Aviation Ramp
Airport Development for Rehabilitation of the south portion of Taxiway A under AIP 26 at FNL. The rehabilitation included a resurfacing of the existing asphalt surface by milling and repaving with asphalt for the parallel taxiway at the airport
Construct Rehabiliation of Asphalt Pavements south portion of Taxiway A
This project will involve the design of the new runway and taxiway system at the Delaware Airpark.  It will include a new Runway 9-27 (4,200' x 75') and a parallel taxiway.  The taxiway will incorporate the old runway pavement (3,582' x 60').
Construct Runway (design, Phase VI)-09/27
and associated ttaxiway connectors are approximately 3000' in length and 50' wide and had severe cracking and spalling.  The cracks were sealed and covered with a self-adhesive engineering fabric prior to the P-401 overlay.  The project improv
Rehabilitate Taxiway D (+/- 3,000 feet by 50 feet) and Overlay
Airport development - The award purpose is to rehabilitate Runway 05/23, which has been successfully completed.
Airport Development.  The purpose of this project is to improve airport infrastructure and safety by reconstructing a parallel taxiway that was in very poor condition.  Construction of the project was successfully completed by contract labor, a
Airport Development Project McCall Municipal Airport, ID (MYL)reconstructed taxiway pavements that were failed or very close to failing.  These taxiways transit aircraft to and from the runway and to and from hangars and Fixed Base Operators.
Airport Development - Rehabilitate Taxiway
This ARRA project at Chicago's O'Hare International Airport is made up of two (2) distinct pieces of work: The replacement of the Runway 10L/28R Post Tension Concrete Pavement (PTCP) and the widening of Taxiway M. The objective of the Runway 10
Runway 9/27 rehabilitation (including Taxiway P paving between Taxiway E and Runway 5/23) Realignment of Taxiway E sout h of Runway 9/27 and Taxiway D removal between Runway 9/27 and newly relocated Taxiway E; at Quad City International Airport
Quad City International Airport MLI-3854-ARRA
International Terminal Expansion at the Chicago/Rockford International Airport, Rockford, Illinois.
Airport Development - Acquire Aircraft Rescure and Fire Fighting Vehicle
Acquire Aircraft Rescue & Fire Fighting Vehicle
Airport Development - Rehabilitate Runway 14/32 Lighting system at the Delaware County Regional - Johnson Field airport in Muncie, Indiana.
Purpose of the project is to rehabilitate Runway 18/36.  The existing primary Runway 18/36 consists of full depth asphalt pavement.  The asphalt is deteriorating and cracking.  The objection of this project is to mill the existing pavement, rep
Airport Development - Construction of a Parallel Taxiway
Extend Taxiway [Phase II Taxiway Extension]
The objectives fo this project at Northern Maine Regional Airport, for which assistance is being sought are:  (1)  Constructing the extension of Taxiway A from Runway 10-28 to the Runway 1 end.  (2)  Full depth taxiway pavement construction.  (
Highway Infrastructure Investment Grant: Available for Use in Any Areas (flexible), Rural Area with Population under 5K
North Lemmon Valley - Heppner Phase 7 - water main installation project
Airport Development-This project will install in-pavement lights along the centerline of Taxiway A at the Logan International Airport terminal area to enhance visibility for pilots at night and during poor weather.
Install Taxiway Lighting [Install Centerline Lights on Taxiway]
This project consists of constructing the Rehabilitation of Runway 18L/36R project at the Mid-Delta Regional Airport in Greenville, Mississippi.  Runway 18L/36R is the outside runway and is the primary runway for this air carrier airport.  Seve
Rehabilitate Terminal Building.  Expands waiting area with increased ceiling height, canopies to reduce heat load and architectural features; adds canopy on land side of building, rehabilitates exterior of building, rehabilitates interior colum
Airport Development - Design and Construct Parallel Taxiway W, Associated Connector Taxiways and Apron from Runway 14/32 to Taxiway U.  Construction of this project will enhance safety by allowing aircraft to taxi from the terminal to the appro
Construct Taxiway - Design and Construct Parallel Taxiway W and Associated Connector Taxiways and Apron (from Runway 14 to Taxiway U)
Airport Development.  Design and reconstruction of approximately 6,744 SY of Portland Cement Concrete (PCC) air cargo (Area D3) north of the terminal concourses.  Work includes demolition excavation, stabilizing fill, base, PCC pavement, draina
This is an airport development project. It can be described as the rehabilitation of pavements on Taxiways 'C' and 'L' and Taxilane 'K', including the replacement of existing taxiway edge lights with LED lights, the replacement of failed draina
Rehabilitate Taxiways 'C'& 'L'; Rehabilitate Taxiways 'D' & 'M'
Acquire Aircraft Rescue & Fire Fighting Vehicle; Construct Aircraft Rescue & Fire Fighting Building
Construct Aircraft Rescue & Fire Fighting Building & Acquire Aircraft Rescue & Fire Fighting Vehicle
Upgrade Edge Lights, Taxiways A, B, C, D, and H; Upgrade Edge Light Base Housings Runway 17L/35R and Taxiway H.
Saw cut groove (7400'x 100'). Mark (7400'x 100') & transition the connecting TWYS to overlay on RW 17-35 Stillwater Regional Airport.
Office of the Assistant Secretary for Administration and Management
Secure meeting space for Prevailing Wage Conference.
Hotels (except Casino Hotels) and Motels
Airport Development.  Jim Hamilton - LB Owens Airport Airfield Pavement Rehabilitation Project - Phase III (Taxiways, taxilanes, and partial apron)
Rehabilitate airfield electrical and lighting system, including new electrical vault, runway and taxiway edge lighting, airfield guidance signs and precision approach path indicators (PAPI) lights that were damaged in Hurricane Ike which will i
Rehabilitate airfield electrical and lighting system, including new electrical vault, runway and taxiway edge lighting, airfield guidance signs and precision approach path indicator lights. Intergrate standby power into the terminal building
Construct Taxiway L (Phase 1) - this project will include design and construction of new aircraft deicing facilities at the runway ends.  End of runway deicing facilities will include new portland cement concrete paving, glycol collection syste
Airport Development: Non primary development projects in state block grant program (Burlington Municipal Airport: Rehabilitate Runway)
Non primary development projects in state block grant program (Burlington Municipal Airport: Rehabilitate runway)
VPP-RT 34, CR 43B AT VENICE CTR TO SKILLET/MOSHER RD, CAYUGA
VPP-RT 11/41, CITY OF CORTLAND TO VILLAGE OF MCGRAW, CORT CO
Other Commercial Equipment Merchant Wholesalers
CR 143, DAWSON CORNERS ROAD/BOARDMAN CREEK, SENECA CO
COLLEGETOWN TRAFFIC SIGNAL REPL, CITY OF ITHACA, TOMP CO
COLUMBIA STREET PEDESTRIAN BRIDGE, CITY OF ITHACA
BOSTON BIOMEDICAL RESEARCH INSTITUTE, INC.
This ARRA award is a supplement to support summer stipends for two undergraduate research students who will receive training in biomedical research while contributing to ongoing research for the parent project.
. This project seeks to support primary care physicians, as well as families and educators, in meeting these challenges by providing a Web-based information and resource access system. The Utah Collaborative Medical Home Project (UCMHP) has dev
This administrative supplement is to accelerate the pace of the parent project by providing additional curation and programming resources for the International Mouse Strain Resource (IMSR). The IMSR facilitates access to mouse resources and mou
INTERNATIONAL MOUSE STRAIN RESOURCE (IMSR)
ENHANCEMENT OF THE HIV AND SUBSTANCE OF ABUSE LABORATORY CORE. The enhancement of the HIV and Substance of Abuse Laboratory Core (H-SALC) will advance our present efforts of providing human resources and infrastructure needed to support researc
Universidad Central del Caribe Biomedical Research Centers/Administrative Supplement to Advance Translational (T1&T2) Research
ARRA funds are being used to contract with HS Medical Billing a policy consulting company to develop a public health action plan for local public health agencies (LPHA) to bill health insurance plans.  The public health plan shall include a bil
The purpose of this grant is to develop “best practices” for monitoring school (kindergarten) vaccination coverage, entry requirements, and exemption rates, using innovative approaches.  Develop, implement, and evaluate a system to monitor
ARRA - 317 Immunizations & Vaccines for Children - Best Practices
Section 317 Immunization Plan. The overall purpose of the funds are to stabilize State and local government budgets, in order to minimize and avoid reductions in essential services and counterproductive state and local tax increases. This grant
The Cancer Biology Training Grant (CBTG) at the University of Minnesota Masonic Cancer Center combines rigorous training in laboratory-based cancer research with interdisciplinary and translational perspectives that prepares CBTG trainees for i
This renewal proposal describes plans to continue a vigorous chemistry-biology interface (CBI) predoctoral training program that is designed to train scientists in key aspects of fundamental organic and biological chemistry as well as in scient
This adminstrative supplement provides funding for three additional pre-doctoral trainee positions for the existing 'Training Program in Quantitative Biology and Physiology.' In the spirit of ARRA goals, the additional slots will be used for ne
Training Program in Quantitative Biology and Physiology
The objectives of this training program is to provide significant biological training to students receiving in-depth training in synthetic/mechanistic chemistry and to provide significant training in synthetic/mechanistic chemistry to students
This administrative supplement supports an additional predoctoral position on an existing Institutional Training grant in Cellular, Biochemical, and Molecular Sciences, T32GM065094, that was awarded to the Watson School of Biological Sciences a
CSHL Watson School of Biological Sciences
UNC Predoctoral Training Program in Bioinformatics and Computational Biology  Bioinformatics and computational biology are two related disciplines that have developed from the need to analyze and interpret large, complex datasets which have eme
UNC Predoctoral Training Program in Bioinformatics and Computational Biology
at USC. CBM Trainees have diverse backgrounds and research interests, come from many parts of the U.S. and foreign countries, and include under-represented minority students. In addition to the requirements of their Ph.D. programs, Trainees be
Training in Cellular, Biochemical and Molecular Sciences
We have designed a training program for PhD students in Bioinformatics, Genome Technology and Computational Biology. Once it became apparent that modern biology would be increasingly dependent on quantitative methods, several approaches to trai
BIOINFORMATIC AND COMPUTATIONAL BIOLOGY TRAINING PROGRAM
This program will prepare scientists for research careers in the computational analysis and mathematical modeling of medically significant biological systems through interdisciplinary training at the protectoral level.  Noted for its well-estab
Computational and mathematical modeling of biomedical systems
Mount St. Mary's College will create a comprehensive interdisciplinary curriculum for Biology majors that will increase students' understanding of and ability to use theory and quantitative concepts in the biological sciences. This curriculum w
MARC Curricular Improvement Implementation Phase II - New Biology
The purpose of this award (of a Revision Application) was to begin fulfilling a need of the NIAAA-funded INIA West consortium to use electrophysiological methods to study the function of gene products suggested by the molecular components (part
ELECTROPHYSIOLOGY OF ALCOHOL IN EXTENDED AMYGDALA
The overarching goal of the Integrative Neuroscience Initiative on Alcoholism (INIA)-West Consortium is to identify the molecular, cellular, and behavioral neuroadaptations that occur in the brain reward circuits associated with the extended am
Proteomic Dissection of Withdrawal-Induced Excessive Drinking
.  The Kuakini Honolulu-Asia Aging Study (Kuakini HAAS) is comprised of an autopsy component (the parent cooperative agreement for this request) and a closely linked, complementary component involving living Kuakini HAAS participants.  The cent
Epidemiology of Aging and Dementia-Autopsy Research
This recovery act administrative supplement to the Multicenter AIDS Cohort Study (MACS) will support work to discover if the disease variant responsible for host control of HIV resides within the HLA-B/-C haplotype block initially identified by
Multicenter AIDS Cohort Study HLA Supplement
Multicenter AIDS Cohort Study (MACS): Role of viral coinfections in HIV-1 disease progression in the MACS  The overall objective of this proposal is to obtain a comprehensive dataset on herpesvirus and GB virus type C (GBV-C) load in blood and
'The Study to Help the AIDS Research Effort (SHARE) was funded by NIAID and NCI in 1983 to study the natural history of infection with human immunodeficiency virus, type 1 (HIV). SHARE, along with similar sites in Chicago, Pittsburgh, and Los A
MULTICENTER AIDS COHORT STUDY - PART B (BALTIMORE CENTER)
This project will give undergraduate college students and one summer faculty member from a non-research intensive local college an experience in a professional research lab performing discovery research, as well as exposure to entrepreneurship
UNAIDS estimates that 14,000 persons are newly infected with HIV every day throughout the world, of which one half are between the ages of 15 and 24. New infections occur despite widespread awareness of the modes of HIV-1 transmission, and the
CHEMOPROPHYLAXIS FOR HIV PREVENTION IN MEN
The objective of this Administrative Supplement is to facilitate clinical validation of a new diagnostic platform for detecting bloodstream infections related to Sepsis by hiring two researchers. The new personnel will increase the tempo of cli
A rapid and expandable nucleic acid platform to detect bloodstream infections
This is an application for an administrative supplement to the East Africa Regional IeDEA Consortium (?eDEA-EA), described below, which has approved funding until 8/31/2011. This application aims to create an immediately operational statistical
1. Accelerating progress on the parent grant, 'Effects of insulin-dependent diabetes resistance alleles on COB tolerance in NOD', by increasing the size of our mouse colonies held at Taconic and at Scripps so that more experiments can be perfor
Effects of Insulin-Dependent Diabetes Resistance Alleles on CD8 Tolerance in NOD
There are more persons who die from lung cancer than from breast, colon, and prostate cancer combined. The objective of the Genetic Epidemiology of Lung Cancer Consortium (GELCC) is to conduct family-based studies to identify susceptibility gen
To date, one must conclude that the pace of progress in disease control and preservation of functional integrity and quality of life for pediatric brain tumors remains below that of most other major types of childhood cancers. Recent advances i
Although the costs of Prostate-Specific Antigen (PSA) screening for prostate cancer have been clearly documented, the benefit is still uncertain despite the recent publication of two large-scale screening trials. The US trial found no benefit o
Modeling US Prostate Cancer Trends: PSA, Treatment & Ra*
It is planned to apply the stochastic model developed earlier to breast cancer issues associated with the U.S. population. Among the issues which will be studied are: estimating the U.S. breast cancer mortality for the period 2005-2020; investi
Breast Cancer: Role of Early Detection, Treatment and Prevention
This award will be used to expand ?Imi Hale ? Native Hawaiian Cancer Network?s capacity to meet the demand for culturally tailored cancer education expressed by agencies serving Native Hawaiians and Pacific Islanders. ?Imi Hale has invested 10
The non invasive approach to the diagnosis of lung cancer remains a priority in biomarkers development at a time when markers of response and of prognosis are being developed rapidly. These should help us detect the disease at the preclinical l
The Center to Reduce Cancer Health Disparities (CRCHD) of the National Cancer Institute (NCI) announced, for the fiscal year of 2010-11, the opportunity for grantees to seek administrative supplemental funding for cancer health disparities (CHD
DC City-wide Patient Navigation Research Program/Transdisciplinary Geographic Management Program (GMaP)
Hepatocellular carcinoma (HCC) accounts for an estimated 600,000 deaths annually, and in North America mortality due to HCC has nearly doubled in the last 20 years. Recently it has been shown that the signaling pathway controlled by the mammali
The Role of mTOR Signaling in Hepatocellular Carcinogenesis
This proposal builds on a rich resource of bladder cancer (BC) cases and controls derived from two ongoing BC studies at the University of Texas M.D. Anderson Cancer Center, and from two large independent U.S. BC studies - the New England BC St
GENOME-WIDE ASSOCIATION ANALYSIS OF BLADDER CANCER
The Connecticut Emerging Infections Program is addressing the increased public health threat posed by healthcare associated infections by enhancing our statewide EIP activities in collaboration with the CDC EIP network that performs enhanced su
American Recovery and Reinvestment Act (ARRA)  Emerging Infections Programs (EIPs) Healthcare-Associated Infections Program - Innovations in the Surveillance of Mulitdrug-Resistant Organisms and Healthcare-Associated Infections
This proposalseekstoprovidecontinuedsupportfor the New YorkState EmergingInfectionsProgram (NYSEIP). The NewYork State Departmentof Health(NYSDOH), in conjunctionwiththe Universityof Rochester(U of R) andthe NewYork City Departmentof Healthand
Purpose of the Supplement: This Administrative Supplement to Look AHEAD will increase the scientific impact of Look AHEAD and retain and/or create new staff positions at each of 15 local sites and the Coordinating Center. These requests paralle
Action for Health in Diabetes (Look AHEAD)
Look AHEAD is randomized clinical trial examining the long-term health effects of an intensive weight loss intervention in approximately 5,145 overweight volunteers with type 2 diabetes. Participants are randomized to an intensive lifestyle int
Clinical Center for Look AHEAD: Action for Health in Diabetes
We will hire one additional full-time Research Assistant for 10 months to work on the CRIC Study. The proposed personnel addition will allow us to accelerate the tempo of the CRIC Study at our Clinical Center by streamlining and speeding up the
Chronic Renal Insufficiency Cohort Study II
ARRA - Clinical Study of Vesicoureteral Reflux in Children.  This project has two primary objectives related to the on-going RIVUR trial.  One objective is to develop a centralized medical image data management system for use in the RIVUR study
ARRA - Clinical Study of Vesicoureteral Reflux in Children
During the first phase of the AMDCC our group at TJU studied the decorin KO diabetic mouse. Our hypothesis was that decorin acts as an endogenous protective factor by inhibiting active TGF-b. We found that decorin is indeed protective, as decor
ADIPONECTIN AND NOX 4 IN DIABETIC KIDNEY DISEASE
We propose to increase the output of our modENCODE project by adding staff to collect chromatin and to produce transgenic BAC tagged transcription factors for which antibodies are not readily available, With current resources our annual product
A CIS REGULATORY MAP OF THE DROSOPHILA GENOME
Augment data submission and computational analysis with partial support for bioinformatics on our project. This position will prepare data for submission to the public modENCODE database (DCC).
Genome-wide profiling of histone variants in Drosophila and Caenorhabditis
The purpose of the original funding opportunity (RFA-HG-07-005: Genome-Wide Studies in Biorepositories with Electronic Medical Record Data (U01)) was to provide support to develop necessary methods for, and then to perform, genome-wide associat
Identification of G*E interaction terms for common diseases represents a top priority for the Gene Environment Association Studies (GENEVA) consortium of investigators. We propose a cohort specific, hypothesis-driven strategy to filter high thr
ARRA-Genes and Environment Initiative in Glaucoma
Purpose of Supplement.  This administrative supplement complements the goals of the parent PAGE project. It provides funds to genotype additional susceptibility variants in approximately 2,500 African American study participants in CALiCo – P
PAGE: Genetic Epidemiology of Causal Variants Across the Life Course - ARRA
The Human Microbiome Project (HMP) is an NIH Roadmap program that will produce unprecedented amounts of information about the microbial communities living on and within humans. The objective of our current work is to provide a Data Analysis and
A Quality Assurance, Coordination and Analysis Center for HMP
Project iMPPACS provides the first large-scale test of a culturally targeted TV and radio campaign to reduce HIV-associated sexual risk behavior among 1,600 African-American teens in four mid-sized cities in the U.S. Initial findings offer evid
A Multilevel HIV-Prevention Strategy for High-Risk Youth
Silent Cerebral Infarct (SCI) is the most common cause of severe neurological disease in children with sickle cell anemia, occurring in 22% of this population prior to their 18th birthday. The overall goal of this trial is to determine whether
SILENT CEREBRAL INFARCT MULTI-CENTER CLINICAL TRIAL
Intravenous recombinant tissue plasminogen activator (IV rt-PA) is an effective therapy for acute ischemic stroke but has substantial limitations when used alone to open occluded major extracranial and intracranial arteries. The EMS and IMS I P
Interventional Management of Stroke Study III
.  The National Surgical Adjuvant Breast and Bowel Project (NSABP) is a clinical trials cooperative group with a 50-year history of designing and conducting clinical trials that have changed the way breast cancer is treated, and, more recently,
The cohort for this project is a group of 400 (111 of the original 118 at the UH site are still active and we expect to examiner 108 in year 11 of the study) ethnically diverse, myopic young adults currently 17-123 years of age with 11 years of
Collaborative Observational Study of Myopia in COMET Children (COSMICC2) - UH
To conduct preliminary comparisons of measurements of macular thickness, optic disc parameters, intraocular pressure (IOP) and central corneal thickness (CCT) between non-myopic young adults and COSMICC subjects.  The study is designed to test
Collaborative Observational Study of Myopia in COMET Children 2 Center
GirlTalk is a research program with a goal to extend interpregnancy intervals for parenting teen mothers through building their positive relationships, healthy reproductive practices and strong youth assets to enhance attitudes and behaviors as
Cooperative Perinatal Studies and Interventions
DESCRIPTION (provided by applicant): Pelvic floor disorders (PFD) including urinary incontinence, pelvic organ prolapse (POP), and fecal incontinence affect a substantial proportion of women in the U.S. PFD result in significant psychosocial co
involved in the human clinical response to kidney transplantation. However, the supplement is also justified by bringing a new co-investigator into the project, creating new jobs and maintaining existing jobs in compliance with the objectives
The central theme of our research under is to develop lentiviral engineered T cells for treatment of HIV. After successful completion of the aims as set forth in our original IPCP application, we find ourselves in a unique position to directly
LENTIVIRUS-BASED IMMUNOGENE THERAPY FOR HIV INFECTION
The threat of radiological attacks has grown in recent years, warranting a concerted effort to translate the molecular advances of radiation research into bonafide medical products. These medical products must be directed toward the identificat
Centers for Medical Countermeasures Against Radiation
Current HIV-1 vaccine candidates based on recombinant adenovirus serotype 5 (rAd5) vectors are promising but may prove limited by the high prevalence of pre-existing anti-Ad5 immunity in the developing world. To overcome this problem, we have c
NOVEL HETEROLOGOUS ADENOVIRUS PRIME-BOOST HIV-1 VACCINE
Supplemental funds are requested for the recently awarded U19AI083008, “Immune Mechanisms That Control Ectromelia Virus (ECTV) Infection” (PI, Sigal, 5/1/2009-4/30/2014). The requested supplemental funds will be used for the purchase of equ
Immune Mechanisms That Control Ectromelia Virus Infection
We intend to use chemical screening to identify novel inhibitors of infection by influenza virus H1N1 and their cellular or viral targets. Such inhibitors may permit the development of drugs that act in a new way to block influenza broadly, che
DISCOVERY AND ANALYSIS OF SYNTHETIC TLR AGONISTS AND ANTAGONISTS
To increase the number of temporal bone pledges from select ear diseases and to develop specimen-processing techniques for future temporal bone acquisitions - as well as protocols for bones currently in the HEI collection - that will allow the
Cell and Molecular Analysis of Human Temporal Bones
E. coli community information Resource, EcoliHub, will permit full use of existing knowledge and enable new discoveries for a deeper understanding of life processes. These tools and the advances they allow will greatly impact human health both
Development of the www.ECOLICOMMUNITY.org Information Resource
The overarching goal of the Function BIRN (FBIRN) is to develop technology and methods to conduct multi- site functional imaging studies, and to produce a knowledge base that would not otherwise be available through single-site imaging studies.
NATIONAL ASSOCIATION OF COUNTY AND CITY HEALTH OFFICIALS
Hepatitis B has been an on-going problem in the United States despite a vaccine being available for several decades. One reason is that many who are at higher risk for this infection are difficult to reach because of behavioral risks. In 2007,
STRENGTHEN & IMPROVE THE NATION'S PUB HLT CAPACITY THROUGH NAT'L, NON PROFIT, PRO
Type 1 Diabetes is a series disease for which there is no cure but palliative treatments.  Islet transplantation might represent, if successful, a cure.  The ICR has provided islets of uncompromised quality for basic science, preclinical and cl
HUMAN PANCREATIC ISLET CELL RESOURCE TO CATALYZE COLLABORATIVE DIABETES RESEARCH
This is a supplement to create a partnership in environmental public health.  Within The New England Consortium's hazardous waste worker health and safety training project we will develop a short training curriculum to prepare worker health and
Worker Health and Safety Training Cooperative Agreement - Supplemental
This funding was appropiated under de American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  The ARRA funds are intended to reduce preventable healtchare-assocaited infections through State health department efforts to prevent HAIs
EPI LAB AND LAB CAPACITY FOR INFECTIOUS DISEASES - ARRA HAI
HEALTH AND HUMAN RESOURCES, WEST VIRGINIA DEPARTMENT OF
Project funds may be used to develop a healthcare associated infections (HAI) plan for the state of West Virginia.   Expected deliverables include:  1)  development of plans to address healthcare associated outbreaks; 2)  selection of two or mo
Build capacity in Alaska to develop a healthcare-associated prevention program. Primary activities include hiring a Coordinator to direct program activities; completing a State HAI Prevention Plan that will be submitted to the US HHS by January
The ELC program will coordinate and implement HAI prevention activities and report on progress toward reductions in two or more HHS Action Plan Targets. This will include:  ? State HAI Plan coordinator identified ? State HAI Plan submitted to H
Epidemiology and Laboratory Capacity (ELC) for Infectious Diseases North Dakota - American Recovery and Reinvestment Act (ARRA) - Healthcare-associated Infections (HAI)
Build and sustain a program to prevent health-care associated infections. Key components include development of a comprehensive state plan and solicitation of hospitals to participate in MRSA surveillance and reporting.
Epidemiology Surveillance& Laboratory Capacity for Infectious Disease- ARRA-HAI
To build and sustain a State Program to Prevent Healthcare-Associated Infections by implementing activities to coordinate and report Arkansas HAI prevention efforts, detection and reporting of healthcare associated infection data and establish
ARRA-Building & Sustaining State Programs to Prevent Healthcare Associated Infections
The New York City Department of Health and Mental Hygiene's Bureau of Communicable Disease will participate in the Centers for Disease Control and Prevention sponsored project to evaluate the effectiveness of the Meningococcal Conjugate vaccine
Evaluation of Meningococcal Conjugate Vaccine and Other High-Priority Vaccine Preventable Disease
Assessing Varicella Vaccine Effectiveness in School Settings through Varicella Outbreak Investigations Project. This surveillance project will strengthen public health officials’ ability to rapidly identify cases of varicella in school age po
Epidemiology and Laboratory Capacity for Infectious Diseases (ELC) - ARRA 317-VARICELLA
STATE HEALTH SERVICES, TEXAS DEPARTMENT OF
Grant funds to carry out activities to implement healthcare associated infections reduction strategies, to include: coordinating development of a state HAI prevention plan, enhancing HAI surveillance and reporting from medical facilities, and s
Epidemiology and Laboratory Capacity for Infectious Disease - ARRA Healthcare Associated Infections
The purpose is to improve the state's surveillance of meningococcal disease, and to participate in the ongoing case-control study for the evaluation of meningococcal conjugate vaccine, and other high priority vaccine preventable diseases.
The South Dakota Department of Health (DOH) was awarded funding under Activity A under the American Recovery and Reinvestment Act (ARRA) Preventing Healthcare-Associated Infections (HAI) cooperative agreement announcement to provide for basic s
American Recovery and Reinvestments Act: Epidemiology and Laboratory Capacity (ELC) for Invections Diseases, Healthcare Associated Infections (HAI) - Building and Sustaining State Programs to Prevent Healthcare-associated infections.
Utah Department of Health (UDOH) plans to hire a state HAI coordinator and an information analyst, and to develop and integrate a comprehensive statewide HAI prevention plan, building upon the existing reporting system for HAIs in the state.  A
The overall goals for this award for prevention of healthcare-associated infections is to enhance the capacity to investigate, control and report Healthcare associated infections.  Carry out activities to reduce healthcare-associated infections
Epidemiology and Laboratory Capacity for Infectious Disease-ARRA-HAI
The purpose of this Recovery Act HAI supplement is to address the HHS Action Plan by using the existing ELC cooperative agreement to build and sustain state programs to prevent healthcare-associated infections.  Through this supplement, CDC wil
Each year, novel strains of influenza A virus arise through mutation and manage to infect one-fifth of the human population. We remain woefully ignorant of what specific features determine the success or failure of these 'antigenic drift' varia
This award is for the recruitment of Dr. Maribel Tirado-Gomez.  Dr. Tirado-Gomez's immediate career goals are to develop proficiency in cancer research having the financial and time resources to allow her development as an independent researche
UPRCCC/MDACC: Partnership for Excellence in Cancer Research
University of Puerto Rico, Medical Sciences Campus
This award is to support the recruitment and retention of research staff. The goal of this project is to understand the role of cancer genes in prostate cancer. This knowledge will facilitate an understanding of the functional role of cancer ge
Morehouse School of Med/Tuskegee Uni./Uni. Of Alabama Cancer Center Partnership
As part of the NCI Centers of Cancer Nanotechnology Excellence (CCNE) at Emory and Georgia Tech, we request supplemental support to accelerate the tempo in developing, standardizing, and scaling up two nanoparticle-based cancer drugs - one for
Emory-GA Tech Nanotechnology Center for...Oncology
As CCNE-TR investigators, we are convinced that nanotechnology will make a significant impact on cancer diagnosis and management in potentially revolutionary ways. We share the NCI?s vision that nanoscience applied to cancer research is critica
Center of Cancer Nanotechnology Excellence Focused on T*
The purpose of this Supplement to the Comprehensive SDSU-UCSD Cancer Center Partnership (U54 CA132379) is to achieve objectives that are an extension of the parent grant. This Supplement 'Community Health Educator Administrative Supplement' dir
COMPREHENSIVE SDSU-UCSD CANCER CENTER PARTNERSHIP (2 OF 2)
This administrative supplement proposal requests funds to expand the research scope of Project II ('Pharmacogenetics of Metformin Action in PCOS') of the VCU SCCPRIR program by hiring a part-time Clinical Research Coordinator whose specific rol
Translational Research in Polycystic Ovary Syndrome
Center for Women's Health & reproduction
Center for Women's Health and Reproduction
The focus of our U54 Center is on the hormonal and paracrine regulation of spermatogenesis in humans and rodents. There are three interrelated projects. Project I (Barry Zirkin and Jonathan Jarow) is addressing the biological mechanisms that ex
HORMONAL AND PARACRINE REGULATION OF SPERMATOGENESIS
The funds for this ARRA supplement will be used to scale up our activities in comprehensive cancer genome analysis by sequencing TCGA samples using whole genome or whole exome approaches across multiple cancer types.  We are currently working w
Large Scale Sequencing and Analysis of Genomes
The project proposed additional TCGA sequencing and analysis.  We propose an approach that combines the power of four distinct sequencing methods to discover somatic events in human cancer genomes, and that should scale linearly depending on th
CENTER FOR LARGE SCALE GENOME SEQUENCING AND ANALYSIS
In this Administrative Supplement request, we propose funding to expand the UW ENCODE Project in four key areas.   First, we plan to perform deep sequencing / digital genomic footprinting for 15 additional cell types.  Second, we plan to boost
A Comprehensive catalog of human DNasel hypersensitive sites
This supplement will be used for conducting the following four activities and actions that will mainly provide experiences that educate clinical and translational scientists in the creation of partnerships that promotes translational research:
PUERTO RICO COMPREHENSIVE CENTER FOR HIV DISPARITIES  (NCRR ARRA Supplement -Workforce Development)
The long-term goal of the Morehouse School of Medicine (MSM) RCMI Center of Excellence in Clinical and Translational Research (R-CENTER) is to train the next generation of minority clinical and translational scientists to pursue multidisciplina
RCMI Infrastructure for Clinical and Translational Research (RCTR) (U54)
There are many efforts and current initiatives to ameliorate disparities, yet the burden of cancer remains high particularly among many racial/ethnic groups. In order to address this problem, NCI’s Center to Reduce Health Disparities (CRCHD)
Ponce School of Medicine - Moffitt Cancer Center Partnership
The proposed project will promote expanded and improved community engagement (CE) by academic medical centers (AMCs) through two related activities: 1) collaboratively rewriting the CDC's seminal 'Principles of Community Engagement' (PCE), and
DCRI #4866 NCRR ARRA Supplement Community Engagement
This application is in response to the NCRR Administrative Supplements for Research Workforce Development and Dissemination. Training in Health Informatics for practitioners, clinical and translational scientists, and healthcare leaders is crit
CTSI Supplement - Research Workforce Development and Dissemination
This NCRR Administrative Supplement Request for Research workforce Development and Dissemination seeks support for the Irving Institute for Clinical and Translational Research (IICTR) at Columbia University seeks to leverage its clinical/transl
Clinical and Translational Science Award-Advancing Institutional Efforts to Support Research Mentoring for translational Scientists
An essential element of the RFA entitled Institutional Clinical and Translational Science Award, CTSA, is the creation of an academic home that is a department, center, or institute. In response to the RFA, the University of Iowa will create Th
University of Iowa Clinical and Translational Science Program
This proposal seeks to advance T1 and T2 translational research at the Washington University Institute of Clinical and Translational Sciences (ICTS) by establishing a new multidisciplinary Lifestyle Intervention Research Core (LIRC) to assess l
WU INSTITUTE OF CLINICAL & TRANSLATIONAL SCIENCES
The ultimate goals of the University of Chicago CTSA program are to train scientists and health care providers at the University, our partner institutions, and our community to determine the molecular underpinnings of disease or disease predisp
TRANSLATIONAL RESEARCH AT THE UNIVERSITY OF CHICAGO (UL1)
The purpose of this application is to enhance both the process and benefits of clinical andtranslational research by bringing together the diverse resources of the Johns Hopkins Medical Institutions (JHMI) and creating a new model for carrying
INSTITUTE FOR CLINICAL AND TRANSLATIONAL RESEARCH (UL1)
The CTSA Leadership has recognized training and career development of clinical and translational scientists as a strategic goal, calling for open access to training resources across the CTSA Consortium, and for the development of mentorship tra
Institutional Clinical & Translational Science Award (UW-Madison)(UL1) NCRR ARRA Supplement - CTSA Mentor Goal
This CTSA supplemental award is to accelerate the involvement of engineers in the biomedical research and translation process at Northwestern University by 1) instituting a new structured training program in clinical and translational research
Multidisciplinary Clinical and Translational Science (MCTS) Program (UL1)
True community engagement in Clinical and Translational Research (CTR) is unlikely to occur until our CTR work force is diversified. The purpose of this ARRA administrative supplement is to establish a bi?directional CTR Scholars Program in col
Stanford Center for Clinical and Translational Education and Research(SCCTER)UL1
Community Leadership and Reciprocal Development to Advance Community Engaged Research at Two CTSA Institution There is a growing recognition that translational research benefits from community engagement at the outset. The NC Translational and
Community leadership and reciprocal development to advance community engaged res
The Ohio State University (OSU) Center for Clinical and Translational Science (CCTS) will develop a Summer Research Experience Program (SREP) to employ high school students and science teachers to work with clinical and translational research s
(ARRA) CTSA -- Summer research experience supplement
In May 2008 The Ohio State University was awarded a Clinical and Translational Science Award to improve the quality of patient care in the community through a transformative clinical and translational science discipline that is at the core of t
(ARRA) Administrative supplement: Pilot and collaborative translational and clinical studies
This Recovery Act Administrative Supplement requests funding to advance and accelerate the translational research programs being supported by the Imaging Core of the Clinical and Translational Science Award (CTSA) program of the University of T
INSTITUTE FOR INTEGRATION OF MEDICINE & SCIENCE: A PARTNERSHIP TO IMPROVE HEALTH
US 2 - From 3 Miles W Jct 52 E TO 1 Mile W Jct 83
RT 5 FROM THE VILLAGE OF LIMA TO ONTARIO COUNTY VPP
Develop interpretive concept plan for exhibits at Southeast Louisiana NWR Complex in Lacombe, LA. From final concept plan, design, fabricate, and install exhibits selected by SELA.
Showcase, Partition, Shelving, and Locker Manufacturing
ND 37 - From 1 MI W JCT 1804 E & S TO Emmet Corner
RT 39 FROM RT 98 TO EAGLE ROAD EDGEDRAIN MBC
SR 50 FROM W OF AVALON RD SR 429 (WESTERN BELTWAY)
CITY - WILTON MANORS VARIOUS LOCATIONS STREETSCAPE
BLUEGILL TRAIL FROM RIVERBEND PARK TO SANDHILL CRANE PARK
COUNTY ROAD 476W FROM HERNANDO COUNTY LINE TO SW 22 WAY
CR574/SPRING HILL DR FROM PINEHURST DR TO DELTONA BLVD
SR 5/OVERSEAS HWY. AT EAST RIDGE ROAD (MILEMARKER 86.8)
SOMBRERO BEACH ROAD FROM END OF ROADWAY TO AVENIDA PRIMICERA
HARBOR DRIVE FROM WEST MCINTYRE DRIVE TO CYPRESS DRIVE
S.W. 328 STREET FROM S.W. 167 AVENUE TO S.W. 137 AVENUE
WEST 53RD STREET FROM WEST 8TH AVENUE TO WEST 4TH AVENUE
CR 220B/KNIGHT BOXX FR: SR 21/BLANDING BLVD TO: CR 220
SE 18TH AVENUE FROM SE 21ST LANE TO SE 31ST STREET
CR 2 FROM: GEORGIA STATE LINE TO: CR 121
LAKESHORE DR FROM PRESTON COVE RD TO KING FISHER DR
CR 19A FROM DODSON CUTOFF TO AZALEA DRIVE
8TH STREET FROM CARSWELL AVENUE TO GROVE AVENUE
SR 915/NE 6 AVENUE FROM NE 113 STREET TO NE 121 STREET
NE 96 STREET FROM N. MIAMI AVENUE TO NE 2 AVENUE
IVES DAIRY ROAD FROM HIGHLAND LAKES BLVD TO N.E. 24 AVENUE
SW 296 STREET FROM SW 177 AVENUEN TO US-1/SOUTH DIXIE HWY
FLEMING STREET FROM NASSAU LANE TO BAHAMA STREET    (ADA)
TELEGRAPH LANE FROM CAROLINE STREET TO GREENE STREET    (ADA)
WHITEHEAD STREET AT PETRONIA STREET (ADA)
CITY OF NO MIAMI BCH CITYWIDE SIDEWALKS (VARIOUS LOCATIONS)
SR 948/N.W. 36 ST. FROM N.W. 57 AVENUE TO N.W. 42 AVENUE
MIAMI-DADE CO COMMSN D9 - PAVEMENT MARKING @ VARIOUS LOCATIONS
S.W. 77 AVENUE FROM S.W. 136 STREET TO S.W. 104 STREET
S.W. 288 STREET FROM SR 821/FL TURNPIKE TO S.W. 132 AVENUE
LAKE WALES TRAIL FROM SR 17 TO 4TH STREET
CALHOUN COUNTY THERMO STRIPING 2009 ECONOMIC STIMULUS
GADSDEN COUNTY PAVEMENT MARKINGS 2009 ECONOMIC STIMULUS
LUCY ST FROM MAGNOLIA DR HILLCREST ST SIDEWALKS
Byrne Justice Assistance Grant award from the Bureau of Justice Assistance, American Recovery and Reinvestment Act
Recovery Act Edward Byrne Memorial Justice Assistance Grant Program Local Solicitation.  Funds to be used to purchase crime scene vans, crime scene equipment and portable radios.
2009 ARRA Justice Assistance Grant.  The goal for this grant is to purchase equipment to provide safety, efficiency and security for the officers, citizens and visitors of the City of Bristol.
FY 09 Rcovery Act Edward Byrne Memorial Justice Assistance Grant Program Local Solicitation
The purchase of a Records Management System by the Westminster Police Department and to be shared with the Carroll County Sheriff's Department
FY Recovery Act Justice Assistance Grant Program
Police officer overtime for crime prevention and suppression activities focused on violent crimes, specifically robbery and aggravated assaults.
BJA FY 09 Recovery Act Edward Byrne Memorial Justice Assistance Grant.  Goals of this project include: 1. Reduce the use of chemicals by school age youth; 2. Provide education and support to staff and students within a school community; 3. incr
The City of Cody created a new Detective Sergeant Position and this award is being used to purcahse the equipment and supplies necessary to make the new position fully operational.  The officer in the new position will then be able to assist wi
Bennington Police Communications and Investigations Project
Bennington Police Comminications and Investigations Project
The Rumford Police Department Drug enforcement and tactical response program couples equipment purchases and manpower needs into a program to address the drug trafficking occurring within Rumford and surrounding communities. Equipment purchases
Rumford Police Department Drug Investigation and Tactical Response Program
The City of Gardner will utilize their Fiscal Year 2009 Recovery Act JAG in the amount of $61,696 to hlep improve the efficiency of the Gardner Police Department.  Funds will be used to purchase ten desktop computers with a server and related e
FY 2009 Recovery Act Justice Assistance Grant Program.
The Kerrville Police Department identified the necessity to upgrade existing Records Management and CAD (Computer Aided Dispatch) systems in 2009.  The conversion of existing data and the implementation of this project is ongoing and will be co
Interoperable Radio Equipment and In-Car Mobile Computer Technology Projects
Regional records management and field reporting technology project
Regional Records Management/Field Reporting Project
Award funds will be used to purchase vehicles and accessories for new officers. To purchase vehicles for new officers. The vehicles will be marked police cars, to include emergency lights, sirens, speakers, consoles, power supplies and protecti
West Columbia Police Department Enhanced Patrol Equipment Project
The FY2009 Recovery Act JAG Program grant is used to fund the San Rafael Citizen Police Academy.  We are facilitating two academy classes per year from September of 2009 through February of 2013.  These classes allow us to educate the public ab
To purchase law enforcement equipment and supplies. Specifically, the JAG funds will be used to purchase a computerized-voice stress analysis system that includes peripherals and proprietary software, a mobile license plate reader, four cameras
2009 Federally Funded Technology Acquisition
Rockledge Police In-car Digital surveillance system and prevention and educational programs for Neighborhood Watch, Business Watch and City Watch
The Hope Police Department and Hempstead County Sheriffs Office requested JAG funds in the eligible amount appropriated to said agencies of  $75,064. $44,523 would be utilized to purchase targeting equipment, ammunition, and targets to be share
Proactive v. Reactive Community Policing. To Provide a Safer Community
St. Croix County will utilize Recovery Act JAG funding in the amount of $25,003 to support the salary of a newly hired victim services assistant position within the county Victim/Witness Assistance Program. The victim services assistant will be
Electronic records management enhancement; e-ticketing program. Goals of this program are to save officer/records personnel time, increase efficiency, and eliminate written errors by electronically transmitting information onto incident based r
Norwalk City FY 2009 Recovery Act JAG Grant Program - The City of Norwalk will use the Recovery Act JAG award for the Norwalk Police Department (NPD).  NPD will use the grant to fund overtime hours for NPD police officers to continue high visib
Norwalk City FY09 Recovery Act JAG grant program
To retain by partially funding (approximately 25% of a FTE) one of the Community Oriented Policing positions and to preserve COPPS strategies in Norco. Twenty operations or planning sessions with other criminal justice fields where the COPPS sw
Norco Community Oriented Policing Project
The funds for this project will support the supplemental overtime details for police officers participating in the City-Wide Targeted Enforcement Program. This will allow for the targeted enforcement of city-wide violence and quality of life co
Tifton/Tift County Training, Patrol and Communications Improvement Training
Tifton/Tift County Training, Patrol and Communications Improvement Project
The objectives are two-fold: to create a part-time job (0.5 FTE) for a skilled legal assistant in a county suffering from a spike in joblessness, and to prvide a 13-month respite from the budgetary crisis that threatens our ability to carry out
Legal Assistant Reduction-In-Force Relief Grant
Safe Communities To provide funding for overtime and equipment needed for departments to more efficiently and effectively serve the public in Lorain County.
The City of Chicopee will use Recovery Act JAG funds to support the Chicopee Police Department (CPD).  CPD will purchase portable radios and a multi unit radio-battery charger.  The goal is to provide each police officer with a new portable rad
Chicopee City FY 2009 Recovery Act JAG Program
Federal Recovery Act, Dept of Justice grant to update and modernize local law enforcement agency. Sardis Police Department
The Bannock County Sheriff's Office and The Pocatello Police Department continue to use the equipment that was approved and purchased in the manner specified. The Chubbuck Police Department still has not used all of the funds awarded to them.
Bannock County Area Law Enforcement Criminal Division Equipment Program
The Town of Prescott Valley, through the police department, will use the Recovery Act JAG award to enhance existing services provided to the public, maintain a high level of police officer and citizen safety, increase enforcement efforts, and u
Prescott Valley Police Department Local Initiative Enhancement Project
The Cleveland Police Department is using these funds for upgrades to the departmental firing range.  We are also using the funds to purchase taser cameras, SWAT vest and a metal storage facility at our firing range
Upgrade existing radio communications equipment
Purchase of much needed law enforcement equipment and supplies to keep existing officers prepared for day-to-day encounters.
to enhance community notification and law enforcment services in amherst county
This is a Byrne JAG Recovery award to the City of Hickory and Catawba County, North Carolina.  This project includes one additional FTE and two part time telecommunicators.  This grant also includes equipment for the FTE position as well as equ
City of Hickory and Catawba County JAG projects
COMAL COUNTY FY09 RECOVERY ACT JAG PROGRAM
The Webster Police Department proposes to utilize the funding from this grant to update, enhance and expand the technological capabilities of its mobile terminal operations.  In furtherance of these objects, the Department proposes to purchase
Title of project: FY 09 Recovery Act Edward Byrne Memorial Justice Assistance Grant Program Local Solicitation.  This project will promote the efficient administration of justice by making court records more easily accessible to the public, law
FY 09 RECOVERY ACT EDWARD BYRNE MEMORIAL JUSTICE ASSISTANCE GRANT
2009-SB-B9-0786: City of Dubuque and Dubuque County 2009 Law Enforcement and Prevention Project:  Funds were requested for the following:  Overtime funds for the Dubuque Police Department and the Dubuque County Sheriff's Office for illegal drug
City of Dubuque and Dubuque County 2009 Law Enforcement and Prevention Project
Calaveras County Sheriffs Department Gang Enforcement detail
Calaveras County Sheriffs Department Gang Enforcement Detail
To prevent and control crime and to improve the criminal justice system.
Demopolis Police FY 2009 Justice Assistance Grant Program
Justice Assistance Grant. All Prime and Subrecipient (4)funds have been spent. This is a final report.
The city of Chicago and Cook County, as disparate jurisdictions, will share their fiscal year 2009 Recovery Act JAG award in the amount of $28,663,987 to create jobs and promote economic stability through local government budgets, to minimize a
Outagamie County Crime Free Multi-Housing Project
Community/Public Relations Programs: The City of Midland will use the Recovery Act JAG funds to support the Midland Police Department.  The Midland Police Department will provide overtime for officer involvement in community and public relation
CALHOUN COUNTY SHERIFF'S DEPARTMENT Funding purchased new computers. Mobile work stations have shown to be valuable and effective tools. The mobile work stations allow the officers to create incident reports in their vehicle, communicate with C
Calhoun County Law Enforcement Technology Project
The disparate jurisdictions consisting of Cumberland County and the City of Fayetteville will utilize the Fiscal Year Recovery Act JAG award in the amount of $1,043,441 to support personnel and to purchase equipment. The County of Cumberland, s
Support to County Law Enforcement Interoperable Communications and City Police Initiatives to Reduce Crime
At the time of the award, Washington Police Department (WPD) was in the beginning stages of planning to construct a new police facility. This important time in the department required staff be in place to assist with non-police planning activit
Law enforcement equipment for new positions including vehicles and personal equipment for the Sheriff's Office and the Winston-Salem Police Department.  The Kernersville Police Department will equip existing positions with tasers and in-car com
The Recovery Act Funds awarded for the Sheriff's Department Equipment Modernization Project will assist the jurisdiction in purchasing needed upgrades in euqipment required by the Department to enhance officer safety.  It will also assist the j
2009 ARRA Justice Assistance Grant used to fund technology improvements to coincide with moving into a new police facility.  Purchase of new computers.
Grant money will be used to purchase the Barcoded Evidence Analysis, Statistics, and Tracking (BEAST) system built by the Porter Lee Corporation. The system is an extremely valuable tool for maintaining evidence integrity and control, which is
Funding for the purchase of two police cruisers.
BJA FY 2009 Recovery Act Edward Byrne Memorial Justice Assistance Grant
Enhancement of law enforcement program to provide equipment and training materials.
Rockdale County Recovery Act Justice Assistance Grant Program
The Bureau of Immunization (BOI) has begun phasing in the Screening and Immunization System (SIS).  With SIS, data is captured electronically at Department of Health and Mental Hygiene (DOHMH) immunization clinics. SIS includes: new screens des
Supplemental for Innovative Projects to Improve Reimbursement in Public Health Department Clinics
The Immunization Program executed $1,845,000 in grant agreements to 91 local health departments (LHD) which demonstrated vaccine delivery to VFC-qualified infants, children and adolescents during 2008.   Four of the 91 LHDs were unable to spend
ARRA-317 Immunization and Vaccines for Children
The purpose of this grant is to increase vaccination outreach to both children and adults.  This project has specific vaccines that must be used for this purpose. In addition the enhancements are being made to the New Mexico Statewide Immunizat
ARRA-317 To Support Immun & the Vaccines for Children Prog Statewide in New Mexico
ARRA Immunization - Develop a plan to assist public health departments in improving reimbrusement through billing for immunization services and obtaining privately purchased vaccine.
ARRA 317 Immunization and vaccines for Children Grants
Funding will be used to develop the capacity for billing health insurance plans for services provided to health plan members by state and local health department clinics.
ARRA-317 Immunization and Vaccines for Children Grants.  This award will support efforts to plan, develop, and maintain a public health infrastructure for low income children and adults vaccinated against vaccine-preventable diseases.
850 Marina Bay Parkway, Bldg. P, 2ndFloor
Program operations funds awarded through the American Recovery and Reinvestment Act (ARRA) will allow the Immunization Program from the Guam Department of Public Health and Social Services to expand immunization services to help increase the va
I have received  an NIH/NIA Mentored Research Scientist Development Award (K01) to support my growth into an independent investigator whose research focuses on the neurobiological underpinnings of cognitive aging. Two studies will investigate t
Hormone and Neurotransmitter Interactions in Cognitive Aging
In this K01 application, Philip Polgreen, MD, seeks to gain expertise in graph theory pertaining to social networks and in mathematical simulations for developing more effective interventions to minimize the spread of nosocomial infections (spe
Social Networks and the Spread of Influenza and Other Nosocomial Infections
In July 2008, Rachel Winer, PhD received a K01 award (the parent grant) to conduct a longitudinal study of high-risk (HR) human papillomavirus (HPV) infections in 25 to 65 year old women who date online. To date, 220 women have been enrolled (t
This proposal describes a 5 year training program for the development of an academic career in Cardiovascular Transcriptional Biology. The principal investigator has scientific background with expertise in cellular immunology. He will now emba
(ARRA) KLF2 as a novel regular for monocyte activation and function
The objective of the ARRA administrative supplement is to support Dr. Doubeni's accelerated career development program in key scientific areas that will position him to become an independently funded researcher.  The supplement supports  studie
Understanding Racial and Ethnic Differences in Survival from Colorectal Cancer
Hypertension affects approximately 25% of the adult population in the United States and is an important risk factor for death from stroke, myocardial infarction, congestive heart failure, and chronic kidney disease. The distal convoluted tubule
ANALYSIS OF DISTAL CONBOLUTED TUBULE FUNCTION IN VIVO
The human digestive tract is colonized with a dense community of microbes known at the intestinal microbiota. Many normal physiological processes and developmental programs are reliant upon the presence and proper function of the microbiota. In
IN VIVO MOLECULAR ANALYSIS OF PROBIOTIC IMPACT ON ADEFINED MICROBIOTA AND HOST
This application describes a comprehensive research program designed to develop Dr. DeMorrow into an independent research scientist. Through a structured program of seminars, conferences and workshops throughout the duration of the K01 award, s
Endocannabinoid Regulation of Cholangiocarcinoma Cell Growth
Helicobacter pylori are gram-negative pathogens that infect more than 3.5 billion people worldwide.  The work proposed here will explain how DNA damage to H. pylori induces DNA exchange and will lead to treatment modalities that target this pro
DNA Exchange During Stomach Colonization by Helicobacter Pylori
Initially funded for a one-year period, the administrative supplement award, K02-AI076123-S1, has received a 6-month no-cost extension that started on July 1, 2010.  Despite a modest budget ($49,431 in total costs), this award has contributed t
HETEROGENEITY IN CYTOKINE RESPONSES TO HIV-1 INFECTION
Recent advances on retroviral research that members of APOBEC3 (A3) subfamily proteins potently blocks replication of retroviruses have opened a new avenue for the development of antiretroviral therapy for human immunodeficiency virus type 1 (H
MECHANISM OF APOBEC3-MEDIATED INNATE IMMUNITY TO HIV-1
The ARA funds were used to hire a 50% SRA (statistical research associate) for a two year period to work with Dr. Vaughan in making optimal use of key research opportunities. This will  a) enable the hiring of additional technical staff with ne
Established Investigator Award in Cancer Prevention and Control
The goal of this project for an Established Investigator Award in Cancer Prevention, Control, Behavioral, and Population Sciences is to allow Dr. Goodwin to reduce his administrative responsibilities so that he can devote 70% time to mentoring
ESTABLISHED INVESTIGATOR AWARD IN CANCER PREVENTION & CONTROL
Each year, 51,200 people in the US are diagnosed with bladder cancer and 10,600 die of the disease. In addition to tumor invasiveness, metastatic state and nuclear grade, somatic alterations in tumor suppressor genes have been proposed as usefu
This K07 Career Development Award application is designed to expand my career development from cancer etiology to cancer prevention and control. The career development plan rests on mentoring directed by experts in cancer prevention research an
Sun Exposure and Melanoma in Agricultural Workers
Preventing childhood obesity is considered one of the most compelling public health challenges of our time and demands innovative approaches to tackle. An especially novel approach to confronting the obesity epidemic is promoting consumption of
Clinical Outcomes and Survival in Glioma Patients:  The third aim of the parent grant will examine markers of clinical outcome and survival. As discussed below, this analysis is heavily dependent on having detailed treatment and follow-up data
Infection and Inflammation in Adult Gliomas
The award has been used to expedite the testing of clinical bat samples from Bangladesh under Dr. Epstein's original K08 award.  We hired a full-time lab technician named Maria Sanchez who is based at the Center for Infection and Immunity at Co
Risk for Future Outvreaks of Henipaviruses in South Asia
The dimorphic fungi are the most common cause of invasive fungal disease worldwide, causing several million new infections each year.  In the soil, these fungi grow as mold, which produce spores or infectious particles; when inhaled into the lu
ARRA Molecular Mechanisms That Regulate Phase Transition in Dimorphic Fungi
. I propose to hire either a medical student who is seeking time off from medical school, or a recent master's degree graduate. The employment of a research assistant will allow me to leverage the resources provided to me by the K08 award, acce
The pathogenesis of autoimmunity in Hepitits C virus infection
Despite an increase in the repertoire of cytotoxic and targeted therapies, the prognosis for patients with advanced malignancies remains poor. Recent work has supported a stem cell theory for cancer and suggests that an early tissue specific st
TELOMERE SHORTENING AND STEM CELL MAINTENANCE
My goal is to become an independent physician-scientist engaged in basic research with clinical relevance. My training thus far in medical oncology and cancer research has laid a strong foundation for an academic career. This grant proposal wil
Targeting Cancer With Telomerase Interference
The purpose of the administrative supplement is to provide additional funds for the hire of skilled technical personnel to expedite data collection to accomplish the parent grant research goals and to provide research employment opportuniti
Stability of Crosslinked dentin and its clinical application
DESCRIPTION (provided by applicant): I am a physician scientist interested in the molecular & cellular mechanisms of acute pancreatitis (AP). My short term career goal is to use a mouse model of CF to investigate why humans with atypical CF dev
Inflammatory response to pancreatitis in CF mice: sodium & impaired apoptosis
is a request to expand the personnel support for the aim 3 of K08 to determine the in vivo relevance of KLF11 on the neoplastic transformation in Barrett's mucosa. In the last 2 years, intramural (non-federal) funds helped support the extra ef
Growth Regulatory Mechanisms of KLF in Barrett's Epithelium.
Autoimmune pancreatitis (AIP) is a poorly understood form of pancreatic autoimmunity. Understanding AIP had been hampered by the lack of a mouse model of disease. We identified the Tgfbr2^fspKO mouse that develops AIP. Since development of auto
Mechanisms of Dendritic Cell Tolerance in Autoimmune Pancreatitis
Microvascular Endothelial Cells in the Pathogenesis of Chronic Kidney Injury  --   The long-term objective of the proposed research is to understand how changes in renal peritubular capillaries contribute to the pathogenesis of renal interstiti
Microvascular Endothelial Cells in the Pathogenesis of Chronic Kidney Injury
A fully automated cell separator wold allow us to positively isolate F4/80+ cells without manipulation in less than one hour.  This technology minimizes cell death and maximizes our ability to isolate pure populations of macrophages so that we
IMMUNE MECHANISMS IN CHOROIDAL NEOVASCULARIZATION
DESCRIPTION (provided by applicant): The University of California at San Diego (UCSD) and San Diego State University (SDSU) propose to continue a successful institutional research and academic career development award (IRACDA) program for postd
SAN DIEGO IRACDA: PROFESSORS FOR THE FUTURE
This application seeks to develop a postdoctoral training program emphasizing excellence in both research and minority (American Indian) undergraduate education by utilizing well-developed links between the University of MN Medical School Dulut
Postdoctoral Training Program in Duluth, MN
The long-term goal of this proposal is to define signaling pathways that control oncogenic transformation and epithelial to mesenchymal transition (EMT) of lung cancer cells. The secreted Wnt proteins, which signal through the Frizzled (Fz) fam
The effect of Wnt pathway signaling in NSCLC
The principal investigator conducts translational research in Human Immunodeficiency Virus (HIV) and explores questions relating to HIV drug resistance and the impact of low-frequency mutations on clinical outcomes.
Emergence of HIH drug resistance: Low-frequency mutations and associated factors
Lung involvement is currently the leading cause of morbidity and mortality in scleroderma (SSc) patients. Interstitial lung disease (ILD) is the most common pulmonary manifestation and may result from an abnormal immune response carried out by
T CELL RESPONSE IN SCLERODERMA LUNG DISEASE: FROM PATHOGENESIS TO CLINICAL CARE
Clinical and Behavioral Determinants of CKD Disparities is an award to support the career development of Dr. Leigh E. Boulware at Johns Hopkins University School of Medicine. Through a structured didactic plan and the conduct of several studies
CLINICAL AND BEHAVIORAL DETERMINANTS  OF CKD DISPARITIES
Acute lung injury (ALI) is a severe complication of trauma with major short and long-term consequences.  ALI is the earliest and most frequent manifestation of multiple organ failure, the leading cause of death among trauma victims surviving th
Trauma and Acute Lung Injury: The Role of Red Blood Cell Storage and Transfusion
Parent award is to build the foundation for a programmatic line of research to develop and test psychosocial treatments to improve treatment adherence and clinical outcome for patients with mood disorders.  The supplement will contribute substa
Motivational Interviews Adapted to Improve Depression Treatment in Primary Care
This award will provide resources to pursue further research in understanding human autoimmune diseases and will allow mentoring of physician-scientists at various stages of their careers in this area of research.  The studies conducted will di
Dissecting Immune Basis of Disease and Therapy-ARRA Stimulus Admin Suppl
techniques. This project should drive a new generation of theoretical models by providing a new conceptual model for mammalian transcriptional auto-regulationand a new experimental system for quantitativelyanalyzinghow feedback circuitry drive
HOW FEEDBACK CIRCUITRY DRIVES PHENOTYPE SWITCHING IN A HUMAN HERPESVIRUS
Project title: Molecular Mechanisms of Invadopodia Formation and Function. The objective of this K99 supplement is to supplement the studies proposed under my parental K99/R00 with high-throughput screening analyses that will significantly acce
MOLECULAR MECHANISMS OF INVADOPODIA FORMATION AND FUNCTION
This application aims to supplement an active K99 award (NIDCR K99 DE-018954-01, Matrix metalloproteinase gene variants and cleft lip/palate) with the purpose of adding technical personnel. The supplement would allow to promote job creation and
Matrix Metalloproteinase Gene Variants and Cleft Lip and Palate
PUBLIC INSTRUCTION, NORTH DAKOTA DEPARTMENT OF
The North Dakota Department of Public Instruction received funds through the American Recovery and Reinvestment Act of 2009 (ARRA) to pay costs associated with the distribution of USDA foods donated for use in The Emergency Food Assistance Prog
Viruses and Autoimmunity: P01: The hypothesis that human enterovirus infections have the potential to accelerate type 1 diabetes (T1D) onset in humans is well supported by both observational and experimental data. However, epidemiological data
Anti-NMDA receptor antibodies in brain dysfunction: lessons from lupus
This submission is in response to NOT-OD-09-058, entitled 'NIH Announces tlie Availability of Recovery Act Funds for Competitive Revision Applications.' Enzymatic targeting of a radiopharmaceutical for the treatment of EBV-associated tumors is
BONE MARROW TRANSPLANTATION IN HUMAN DISEASE
The central theme of this Program Project involves the relationship among molecular structure, thermodynamics, and biological function. By developing novel biological systems that reflect the mutagenic specificity of a single DNA adduct and by
ARRA: Exocyclic DNA Adducts and Oxidative DNA Damage
Patients treated with topoisomerase inhibitors as part of chemotherapy for solid tumors, develop secondary leukemias with translocations involving the MLL gene, at a rate of up to 5%. The project will involve the use of parallel sequencing of i
Molecular genetics of MLL-associated leukemia
The Administrative Supplement provides funding for two aspects of our rapidly expanding studies in the field of cancer-induced immune suppression.  The proposed additional studies focus on newly discovered and potentially critically important m
Immune Escape in Human Cancer: Mechanisms and Therapeutic Implications
Pancreatic ductal adenocarcinoma (PDAC) is among the leading causes of cancer death, with nearly all cases following a rapid and merciless course of intractable pain, cachexia, hopelessness and death. Repeated cycles of clinical trial failures
Genetics and Biology of Pancreatic Duct Adenocarcinoma
This project explores how a gene family of multi-PDZ domain proteins called the NHERF family which are located in the apical domain of epithelial cells takes part in regulation of intestinal Na absorption by affecting the brush border Na/H anti
Transporters and Trafficking in Polarize
UNIVERSITY OF NORTH CAROLINA AT WILMINGTON
This amended Program Project competitive renewal is focused on revealing mechanisms of action following Florida red tide toxin exposure in laboratory models, and at providing relevant information for humans exposed on beaches. Florida red tides
Effects of Inhaled Florida Red Tide Brevetoxins
The goal of our program project is to understand the mechanisms of drug resistance in treated HIV infected patients. The work supported by the supplement facilitates these studies in two areas. First it enables us to expand our studies to inclu
RESISTANCE DRIVEN STRUCTURAL DESIGN FOR HIV THERAPIES
The overarching goal of this program project is to build bridges across disciplines, linking higher cognitive functions to their underlying neurobiological bases and their molecular genetic underpinnings using a specific genetic disorder, Willi
Williams Syndrome:  Bridging cognition, brain and genes
.  The request includes two summer undergraduate student workers for each of two years in the Component of Marianne Bronner-Fraser; two summer undergraduate student workers for each of two years in the Component of David McClay; and six s ummer
EGG TO EMBRYO: GENE REGULATORY CIRCUITRY IN DEVELOPMENT
This award provides summer research experiences for undergraduate students on project involving DNA virus as vectors for cardiovascular diseases.  The program has three important components: 1) an intense, hands on research experience working c
DNA virus as vectors for cardiovascular diseases
Genetic Studies in Neurological Disorders To date, researchers have completed sequencing 576 individuals for 32 primer sets covering the exonic regions of MECP2, MBD5, MBD6, SETDB1, and SETDB2. From these preliminary results, we have identified
GENETIC STUDIES IN NEUROLOGICAL DISORDERS.
which is beginning its third year of 5 years of funding. The requested funding for three projects and two cores will enable the hiring of one additional technical staff. Consistent with the stated scope of the Administrative Supplement program
Calpain as a Therapuetic Target for TBI (PO1)
This P20 proposal presents a research and educational partnership between the Wake Forest University Comprehensive Cancer Center (WFUCCC) and the Departments of Biology and Chemistry of North Carolina Agricultural and Technical University (NC A
North Carolina A&T University-Wake Forest Cancer Center partnership (2 of 2)
The Latino/Hispanic population is the largest minority in the US and the highest concentration of Latinos is along the US-Mexico Border. To address the specific needs of this population in cancer research and education, a partnership between Th
UTPA - CANCER CENTER AT UTHSCSA BORDER PARTNERSHIP (1 OF 2)
The University of Vermont (UVM) has a long and venerable history of research using rodent models of environmental lung disease developed within a dedicated inhalational exposure facility housed in the College of Engineering at UVM. This facilit
Translational Research in Lung Biology & Disease
The overall goal of the proposed COBRE-funded Center for Alaska Native Health Research (CANHR) is to achieve a permanent and sustainable research center at the University of Alaska Fairbanks (UAF) with the primary theme of investigating obesity
INVESTIGATING OBESITY AND CHRONIC DISEASE-RELATED RISK FACTORS OF ALASKA NATIVES
This two-year proposal is designed to establish a research framework of excellence that can be used to develop new translational insights into the mechanism of heart valve disease with the aim of improving therapy. Our specific goal is to under
SC Cobre for Developmentally Based Cardiovascular Diseases- Administrative Supplements to Advance Translational Research
COBRE: Center for Cardiovascular Research We are submitting this renewal application for the Center of Biomedical Research Excellence (COBRE) at the University of Hawaii (UH) in response to the National Institutes of Health RFA-RR-06-001. The J
COBRE: Center for Cardiovascular Research
Biomedical workforce training in Alaska requires starting with the early foundation in the high schools in isolated local villages.  By engaging students in research early, we engage their parents and communities.  Once begun, we attempt to nud
Alaska INBRE-2:  Environmental Agents and Disease
“Zuni Health Initiative (ZHI) is a NM-InBRE supported (P20 RR016480) community based education project with a major goal of reduction of risk for obesity- and diabetes-related chronic diseases in the traditional Zuni community.  The major obj
ARRA NEW MEXICO IDEA NETWORKS OF BIOMEDICAL RESEARCH EXCELLENCE (INBRE) [P20]
This Request is the New Hampshire portion of a regional effort from the northeast IDeA states (VT, NH, ME, RI and DE) to provide the first fiber-optic backbone through northern New England that connects higher-education and biomedical research
Cellular and Molecular Mechanisms of Lung Disease
The extent to which individuals are vigilant for, versus avoidant of, threatening information has been posited to play a major role in a variety of health outcomes. However, threat-related processing styles have not been adequately assessed in
A major goal of research on human aging is to generate knowledge that will facilitate the maintenance of functional independence in older adult populations. Sensory declines represent a broad category of normal age-related changes that can lead
Aerobic organisms exploit O2 to extract large amounts of energy from oxidative metabolism of food, and employ oxidative reactions for a number of important chemical transformations involved in antibiotic biosynthesis, metabolism of xenobiotics,
Enzyme Mis-Metallation, Consequences and Opportunities
Protein interaction networks are key determinants of protein function in biological systems.  Despite the potential that quantitative protein interaction information could have for all areas of cancer research, global or large-scale quantitatio
Quantitation of protein interactions in cancer cells
The goal of this study is to identify underlying mechanisms, which hinder routine high-level expression of integral membrane proteins using the baculovirus expression system. In this study a rapid cloning system will be employed to generate rec
Baculovirus expression modified for enhanced membrane protein production
Genetically encoded Ca2+ sensors hold great promise for the dissection of complex physiology in vivo.  The ability to make molecular scale measurements in real time in mammals, and to determine lineage –specific signaling events by genetic sp
DESIGN OF GENETICALLY ENCODED CA2+ INDICATORS FOR IN VIVO APPLICATION
The goal of this proposal is to identify the enzymes involved in mammalian mitochondrial one-carbon metabolism and to determine how these enzymes function together to support mitochondrial one-carbon metabolism. Folic acid metabolism is essenti
During the past decade, it has become evident that in vitro enzyme data obtained in solution frequently fail to provide an accurate profile of in vivo enzyme kinetic parameters. This may be due to oligomer formation. Efforts to separate the eff
P450 Protein-Protein Interactions Determined by Selective Protein Manipulation
Type I interferons (IFNa,b) have been widely used for treatment of cancer and virus-infected diseases. Our recent findings suggest that IFN-alpha can have a previous totally unknown signaling event, i.e., lysine acetylation cascade, leading to
Cdk/Cyclin complexes drive progression through the eukaryotic cell cycle. Entry into mitosis is triggered by Cdk1 (Cdc2)/Cyclin B complexes, while M phase exit requires Cyclin B degradation and dephosphorylation of mitotic phosphoproteins. The
The overall purpose of the award is to conduct a lentiviral shRNA screen in human T cells and identify novel genes that are required for T cell receptor signaling and T cell activation. In year 1, we will conduct the full-scale 15,000 shRNA scr
Integrated Functional Genomics Analysis of Druggable T Cell-Activating Genes
Polycystic ovary syndrome (PCOS) is a heterogeneous syndrome affecting 5-10% of women of reproductive age.  It is characterized by elevated circulating insulin, reduced insulin sensitivity, infertility, hyperandrogenism, and a multitude of symp
REDUCED CARBOHYDRATE DIET INTERVENTION FOR PCOS
--the broad goal of this project is to understand how typically developing infants learn about and remember objects. Understanding the typical development of aspects of learning and memory is important for insuring healthy development of all ch
The Development of Object Representation in Infancy
Pain and anxiety in children undergoing surgery continues to be a significant public health issue.  Indeed, every year three million children who undergo surgery will suffer significant pain after surgery and high anxiety prior to surgery.  Man
A Tailored Internet-Based Preparation Program for Perioperative Anxiety and Pain
In many situations people have to process simultaneously presented auditory and visual information, and this ability is especially important for lexical development where auditorily presented words often co-occur with visually presented objects
(ARRA) Cross-modal processing and lexical development
The ~2 Mb Prader-Willi/Angelman syndrome (PWS/AS) domain encompasses a group of imprinted genes that are coordinately regulated by a bipartite imprinting center (IC). The PWS-IC functions to establish and maintain the paternal epigenotype acros
Analysis of the Mouse PWS Imprinting Center
Although the link between maternal and child depression is well established, little is known about the mechanisms by which this risk is conferred. The proposed study is designed to address this gap. In so doing, we seek to integrate and extend
ARRA:Pathways to Depression in Children of Depressed Mothers
Research the pathogenesis of the lysosomal storage disease mucolipidosis type IV (MLIV) is why dysregulation of the ion channel TRPML1 lead to buildup of storage bodies. Finding whether TRPML1 directly regulates membrane traffic or lysosomal li
The therapeutic utility of inhibiting/modulating progesterone receptor (PR) transcriptional activity in uterine fibroids has been well validated both in preclinical models of this disease and in several definitive clinical studies. Indeed, both
The pharmacological actions of antiprogestins in uterine fibroids
Minority children are more likely to experience early academic failure than are non-minority children. Increased risk of academic failure is associated with a host of family factors such as family poverty, maternal depression, low maternal educ
SELF REGULATION AND RACE/ETHNIC DISPARITIES IN SCHOOL READINESS
Post-stroke shoulder pain is a major rehabilitation problem affecting up to 60% of moderate to severely impaired stroke survivors. Surface electrical stimulation (ES) of muscles surrounding the hemiparetic shoulder is the only intervention with
Electrical Stimulation for Hemiplegic Shoulder Pain
We use a multilevel data set (PHDCN) to study young children?s emerging effortful control (EC) in diverse neighborhoods throughout Chicago. We test the explanatory power of characteristics from three environmental contexts -- the mother-child r
Young Children's Self-Regulation in an Urban Context: A Multilevel Analysis
How animals regulate organ size is unknown. Recent studies in Drosophila point towards a novel signaling pathway called 'hippo' as an important regulator of organ growth. Cells that are mutant for components of the hippo signaling pathway exhib
GENETIC ANALYSIS OF THE HIPPO SIGNALING PATHWAY IN THE MOUSE MAMMARY GLAND
The principal determinant of synaptic serotonin (5-hydroxytryptamine; 5-HT) inactivation is the antidepressant-sensitive 5-HT transporter (SERT, SLC6A4). Common polymorphisms in the SERT promoter impact SERT expression and have been associated
Transgenic Mouse Model to Address Heterogeneity in Autism Spectrum Disorders
Today, ontologies are critical instruments for biomedical investigators, especially in those areas, such as cancer research, that require the command of a vast amount of information and a systemic approach to the design and interpretation of ex
Automated Integration of Biomedical Knowledge
Molecular regulation of the myocardin factors in vascular smooth muscle- ARRA  Vascular smooth muscle cell (SMC) differentiation is a very important process during vasculogenesis and angiogenesis, and it is well recognized that alterations in S
Molecular regulation of the myocardin factors in vascular smooth muscle- ARRA
Our approach in elucidating critical pathways involved in the pathogenesis of human COPD has been to identify candidate genes from a comprehensive study of regulated genes in human lung tissues of individuals with COPD. We performed comprehensi
EGR-1: Regulator of apoptosis and inflammation in COPD
A major goal of cardiac research is to develop the means to repair diseased or damaged hearts with newly generated myocardial tissue.  A longstanding paradigm of cardiovascular biology was that the myocardium of the adult mammalian heart is pos
Examining the Cellular Heterogeneity of Adult Myocardium Uning Transgenic Mice
Sickle cell disease (SCD) is one of the most common inherited diseases in the United States. Vasocclusion, resulting in acute, debilitating pain, is the hallmark of SCD often necessitating hospitalization. In part due to SCD patients? need for
RESPECT, TRUST, AND PATIENT OUTCOMES IN SICKLE CELL DISEASE
Nanoparticles are engineered structures with dimension of 100 nanometers or smaller.  Available evidence indicates that the properties of nanoparticles may substantially differ from the same composition in the micrometer scale.  However, the bi
WC-Co nanoparticles in initiating angiogenesis by reactive oxygen species
Hibernating mammals survive without food and water for periods of time and at body temperatures that would normally evoke life-threatening cardiovascular responses in humans. During hibernation, neurons in the central nervous system (CNS), incl
Mechanisms of Neuroprotection in the Nucleus Tractus Solitarius of Hibernators
Diabetes mellitus is associated with a cardiomyopathy that occurs in the absence of hypertension or coronary artery disease and that is characterized by ventricular hypertrophy, decreased ventricular diastolic relaxation, and a reduced peak fil
ALTERED CARDIAC MYOCYTE SIGNALING IN DIABETIC MYOCARDIUM AND FUNCTIONAL SEQUELAE
The main function of the vascular endothelium is the mediation and control of the transendothelial exchanges of water and solutes (both small and large molecules) between blood plasma and the interstitial fluid, in short the control of vascular
Structure and Function of Endothelial Fenestrae
Genetic Determinants of Premature Vascular Dysfunction in Families: This is a study to find the genes responsible for prematurely stiff and unresponsive arteries. The study is done in families with a risk of early heart attacks.
GENETIC DETERMINANTS OF PREMATURE VASCULAR DYSFUNCTION IN FAMILIES
Lung transplants have been performed in over 20,000 individuals with advanced lung disease, with two-year survival of 70% and dramatic improvements in quality of life. However, long-term survival rates remain lower than those of kidney, heart,
Bronchoalveolar Lavage Cell Biomarkers in Lung Rejection
The objective of this two-year project is to improve the outcome following heart transplantation by clarifying the mechanisms involved with the induction of donor-specific tolerance via the mixed chimerism approach. Tolerance of kidney allograf
Optimizing Mixed-Chimerism for Heart Transplantation in Non-Human Primates
Pressure overload-induced cardiac hypertrophy due to valvular or hypertensive heart diseases is one of the most common causes of congestive heart failure in the U.S. During the last decade, many efforts have been focused on the elucidation of t
Cardiovascular disease (CVD) and its associated risk factors such as hypertension and dyslipidemia constitute a major public-health burden due to increased mortality and morbidity and rising health care costs. Massive epidemiological data are n
DEVELOPMENT OF DATA ONTOLOGIES FOR INTEGRATING MULTI-CENTER CARDIOVASCULAR STUDIE
Myeloproliferative disorders (MPDs) are a group of conditions characterized by chronic increases in some or all of the blood cells (platelets, white blood cells, and red blood cells). Recently, we and others have identified a mutation in the JA
TYROSINE KINASE JAK2 AND MYELOPROLIFERATIVE DISORDERS
In the United States alone, approximately 500,000 deaths will result from rupture of plaques considered 'insignificant' on an angiographic evaluation. Available screening and diagnostic methods are insufficient to identify possible victims befo
Combined Intravascular Ultrasound and Photoacoustic Imaging of Atherosclerosis
A critical issue for disaster response is group or collaborative computing in mobile environments. This application describes research to address three critical inter-related problems that inhibit the successful use of information technologies
WIISARD SAGE: SELF-SCALING SYSTEMS FOR MASS CASUALTY MANAGEMENT
Predicting Patient Outcomes from Clinical and Genome-Wide Data   Clinical classification and prediction are key components of clinical care. Even modest improvements in classification and predictive performance may have significant healthcare c
Predicting Patient Outcomes from Clinical and Genome-Wide Data
The long-term goal of this proposal is to enhance the manner in which physicians access, process and marshal medical information by providing them with an automatically generated, comprehensive, and up-to date summary of the information appeari
An NLP Approach to Generating Patient Record Summaries
Attention-deficit/hyperactivity disorder (ADHD) is the most commonly diagnosed behavioral disorder in children. Prevalence rates in the United States range from 2% to 18% depending on diagnostic criteria and population studied. Primary care phy
Computer Decision Aid for ADHD Management (CDAAM)
The function of millions of proteins remains unknown, and automated protein function prediction systems have a poor record of performance. We will test hypotheses about protein functional sites by validating high-throughput predictions derived
Automated Literature Mining for Validation of High-Throughput Function Prediction
Abstract  Recent increases in HIV diagnoses, sexually transmitted infections, and risk behavior indicate that research is needed to identify effective positive prevention interventions integrated within HIV primary care settings to reduce trans
BRIEF CARE-BASED HIV PREVENTION FOR NEWLY DIAGNOSED MEN
Little is known about the development of abnormal repetitive behavior (e.g., stereotypies, rituals) in children at risk for autism and related neurodevelopmental disorders.  This lack of knowledge precludes effective early intervention and prev
Development of Persistent Repetitive in Animals
DESCRIPTION (provided by applicant): The long-range objective of the proposed research is to refine, evaluate, and disseminate an Internet-based intervention to prevent eating disorders (EDs) and comorbidities in college-age women. EDs are high
1/2-Preventing Eating Disorders and Reducing Comorbidity
In Crisis Intervention Team (CIT) training, police officers participate in 40 hours of specialized training provided by local mental health professionals, family members/advocates, and mental health consumer groups. Upon completion, these offic
MODELING OFFICER-LEVEL EFFECTS OF CRISIS INTERVENTION TEAM (CIT) TRAINING
Associative learning is supported by the ability to recognize errors between expected and actual outcomes. Evidence from primate and rat recording studies suggests that dopaminergic neurons in substantia nigra and the ventral tegmental area (VT
Errors and expectancies in OFC and VTA and their roles in associative learning
Fragile X Syndrome (FraX) is a developmental brain disorder with abnormal neuron architecture development and functional plasticity of the developing brain, causing mental retardation, learning disabilities and autism.  My lab established the D
Genetic and Developmental Analyses of Fragile X Syndrome
In this project we will apply our in-house software package KELVIN to data contained in repositories established by the NIH, leveraging publicly available data sets in order to formulate more comprehensive models of the genetic architecture of
Combining epidemiologic designs to model genetic risks for psychiatric disorders
We propose a partnership between expert large-scale sequencing centers and a collaborative network of research labs focused on the genetics of autism to utilize novel high-throughput genome sequencing to discover specific genes underlying the s
4%2F5-Elucidating the Genetic Architecture of Autism by Deep Genomic Sequencing
This collaborative application is submitted in response to RFA MH-09-171. The root causes of autism remain unknown, limiting efforts to understand disease heterogeneity, diagnose cases, and prevent and treat disease. Epidemiological findings ha
2/5-ELUCIDATING THE GENETIC ARCHITECTURE OF AUTISM BY DEEP GENOMIC SEQUENCING
Understanding the mechanisms of limbic epileptogenesis may lead to novel disease modifying therapies. We have discovered that epileptogenesis is associated with enhanced activation of TrkB in the mossy fiber pathway of hippocampus. We have also
?Redox signaling in axon guidance: Structure and activity of MICAL? During neural development, axons are guided to their final destination by a large number of molecular cues?attractive and repulsive signals that instruct the cytoskeleton to re
REDOX SIGNALING IN AXON GUIDANCE: STRUCTURE AND ACTIVITY OF MICAL
This project concerns the role of ectopic dentate granule cells in temporal lobe epilepsy. The dentate gyrus is believed to act as a gatekeeper or filter to inhibit the propagation of synchronized discharge through the limbic circuit. In both t
Using Transport to Map the Brain A major challenge in understanding how the brain processes information is defining the circuitry that links neurons into a functional distributed parallel processing network. Intracellular transport is a normal
Due to unprecedented increases in the elderly populations, age-related diseases are expected to increase exponentially in the coming years. Among these, neurodegenerative diseases will be the most devastating in terms of their emotional and eco
Blood-brain barrier (BBB) disruption represents a classic hallmark of central nervous system inflammation and it occurs in a variety of neuropathological conditions. BBB disruption involves remodeling of the brain endothelial cell surface, alte
THE BLOOD BRAIN BARRIER IN NEUROINFLAMMATION
This project is designed to identify genetic variants that confer susceptibility to common forms of epilepsy including i) forms of idiopathic generalized epilepsy (IGE) such as juvenile myoclonic epilepsy (JME), childhood absence epilepsy (CAE)
GENETIC STUDY OF COMMON FORMS OF EPILEPSY
Epilepsy affects about 2.5 million people in the United States. If not properly controlled by antiepileptic drugs, seizure disorders can lead to lower quality of life and loss of productivity. One class of epilepsy is called idiopathic generali
Mechanisms by which T-type calcium channels increase seizure susceptibility
One of the pathological hallmarks of Alzheimer's Disease (AD) is the senile plaque, principally composed of the Abeta peptide. Abeta1-42, the 42 amino-acid peptide fragment of the amyloid precursor protein (APP), has a striking propensity to ag
UNTANGLING AMYLOID PLAQUES WITH PROTEASES
We reported on a limited number of cases that SIVagm infection is completely controlled in rhesus macaques (RMs). Our preliminary results showed that although acute SIVagm infection in RMs is characterized by: high levels of viral replication,
A central issue in the study of mortality and health at the older ages is the long-term effect of early childhood health. This is especially important given that there have been very rapid declines in mortality at the oldest ages which can not
ANTHROPOMETRIC INDICATORS OF CHILD HEALTH FOR RESEARCH ON ADULT HEALTH
cardiac dysfunction may be the result of oxidative stress-induced myocardial remodeling. Our long-term goal is to elucidate signal transduction and cellular and molecular mechanisms by which post-translational modifications of myofilament prot
Oxidative Stress and Myocardial Function
We are investigating the role of FoxP3 transcription factor in the development of T regulatory cells. More precisely, we are analyzing whether FoxP3 interacts with c-jun or c-Fos to sustain development of Tregs.
The Role of FoxP3 in the Regulatory T Cells
Triatomine bugs, commonly known as kissing bugs, vinchuca, chipo, barbeiro, are blood-sucking insects, vectors of the protozoan parasite Trypanosoma cruzi, the causative agent of Chagas Disease. This Disease is endemic in Mexico, Central and So
OLFACTORY AND BEHAVIORAL RESPONSES OF KISSING BUGS (REDUVIIDAE: TRIATOMINAE), VEC
Escherichia coli that produces extended-spectrum beta-lactamase (ESBL) tends to be resistant to many classes of antibiotics. Spread of these multidrug-resistant strains of E. coli in the community may lead to treatment failures of common infect
Epidemiology of Community-Associated, ESBL-Producing Escherichia Coli
The mammalian innate immunity is the first line of the host defense against invading pathogens including viruses. Within the host, antigen-presenting cells such as dendritic cells and macrophages, express a variety of pattern recognition recept
TLR7 mediates immune cell infiltration and homing to combat West Nile virus infection
The study of viral dynamics is one of the most important developments in recent HIV/AIDS research for understanding HIV pathogenesis and antiretroviral (ARV) therapies. However, most studies focused on short-term viral dynamics, and the models
STATISTICAL METHODS FOR LONG-TERM HIV DYNAMIC MODELING AND DESIGN
ARRA Global Regulation of Gene Expression in Streptococcus Pneumoniae
Gammaherpesviruses cause lifelong infection and are associated with various diseases, particularly in immune deficient hosts. The human gammaherpesviruses, Epstein Barr virus (EBV) and Kaposi's sarcoma associated virus, are associated with a nu
Characterization of an animal model of chronic infection and disease
Complement is important part of the innate immune system and is arguably best known for its ability to lyse bacteria, enveloped viruses and eukaryotic cells through a macro-molecular structure known as the membrane attack complex (MAC).  The MA
GENERATION OF COMPLEMENT C9 CONDITIONAL KNOCKOUT MICE AND ANTI-C9 MABS
Highly active antiretroviral therapy (HAART) has dramatically increased life expectancy in HIV infection and by 2015 more than half of HIV patients in the U.S. will be older than 50. Elderly HIV patients often experience comorbidities such as n
Control of HIV drug resistance in older patients
Computational and Experimental Analysis of Tibial Tuberosity Transfers
The normal remodeling of bone requires synchronized activity between bone resorbing osteoclastic and bone forming osteoblastic cells. This synchronization includes the recruitment of osteoblasts and osteoclasts, and the stimulation of osteoclas
OSTEOBLASTIC LINEAGE CELLS REGULATE OSTOCLASTOGENESISVIE CX43 AND GAP JUNTIONS
The Overall objective of the project is to develop mechanism based iNOS / PI3 kinase inhibitor in addition to selenium to increase potency against colon cancer prevention. Several iNOS inhibitors have been reported for prevention of cancers. On
INOS/AKT INHIBOTOR FOR COLON CANCER CHEMOPREVENTION
DESCRIPTION (provided by applicant): Breast cancer is the most common cancer in US women. Environmental and dietary genotoxicants are believed to play a role in women's cancer risk; however, the Long Island Cohort Study failed to find a direct
THE ROLE OF HETEROCYCLIC AROMATIC AMINES IN BREAST CANCER
This study involves conducting secondary analyses of the five waves of longitudinal data from the Youth Asset Study (YAS). The data collection ended in December 2008. The study population consists of 1,117 teen/parent pairs survey participants
A longitudinal analysis of gender, youth assets and adolescent substance use
Opioid-induced glial activation, which compromises pain treatment and contributes to the development of drug addiction and abuse, is regulated via a signaling pathway downstream of toll-like receptor-4 (TLR4), a membrane spanning receptor that
Transforming Clinical Pain Control by Targeting a Novel Non-Neuronal Receptor
ARRA - TRANS-NIH RECOVERY ACT RESEARCH SUPPORT - MDMA (“Ecstasy”) is a popular drug of abuse especially among youth in the population. Use of MDMA is associated with acute physiological effects among which is the development of hyperthermia
Synthesis and Evaluation of Aporphines as MDMA Antagonists
Abstract Dopaminergic transmission in the synapse is primarily terminated by removal of dopamine (DA) into presynaptic nerve terminals via the dopamine transporter (DAT), one of a superfamily of Na+/Cl--dependent neurotransmitter transporters.
PKC-beta Regulation of the Dopmaine Transporter Trafficking
Breakdown in decision making and propensity for risk taking are common features of drug addiction that contribute in part to increased rates of unsafe sexual and drug using practices. Compelling evidence demonstrates that HIV+ drug users are mo
Decision Making and Drug Abuse in the Chicago MACS
Cigarette smoking remains the number one preventable cause of premature death in the U.S. In spite of these avoidable consequences, an estimated 60-90% of smokers motivated to attempt to quit relapse within the first year of their attempt. Rese
Neuropharmacology of Emotion-Cognition Interaction in Nicotine Dependence
Opiate drug abuse and human immunodeficiency virus (HIV) infection/AIDS are two major public health problems. HIV-associated sensory neuropathy (HIV-SN) is the most common neurological complication of HIV infection. The symptoms of HIV-SN are d
Gene therapy of HIV-neuropathic pain with morphine tolerance
Despite significant advances in the understanding of the caries process and in the interventions needed to prevent it, early childhood caries (ECC) remains one of the most prevalent diseases among children in the United States and the world. Th
Beverage consumption and early childhood caries trends
Cilia are microtubule-based organelles that have long been observed on most mammalian cells.  While their presence has been known, their diverse functions in mammalian development and signaling are poorly understood.  Cilia have recently been s
Role of Cilia in Mammalian Tooth Patterning
One of the major challenges in nanomedicine is to improve nanoparticles cell selectivity and adhesion efficiency through designing functionalized nanoparticles of various shapes, sizes, and materials. Recent data on cylindrically shaped filomic
MODELING PARTICLE SHAPE EFFECT IN NANOMEDICINE
Well-regulated attention and memory processes are critical to healthy cognitive development in childhood and beyond. Although nearly all children show dramatic improvements in their self-regulation of these cognitive processes, the etiology of
Attention and Memory: Mother-Child Psychophysiology and Behavior
DESCRIPTION: Spinal cord injury (SCI) leads to a profound reduction in physical activity, resulting in a low exercise capacity and increased risk of mortality. Of note, physical inactivity is approaching tobacco as the leading actual cause of d
FATIGABILITY, GENDER, AND OPTIMAL STIMULATION PARAMETERS AFTER SPINAL CORD INJURY
Westat is conducting this study to validate a new measure of social information processing.  In the first phase, conducted in 2009-2010, parents with children in preschool and kindergarten from a charter school were invited to participate in th
Related Social Information Processing Interview
The central hypothesis to be tested in this application is that TLRR (also known as lrrc67), a recently identified testis-specific protein, functions to localize signaling molecules, including protein phosphatase-1 (PP1), near the nucleus of ma
A Testis Specific Regulatory Subunit of Protein Phosphatase-1
DESCRIPTION (provided by applicant): Subjective expectations are an important determinant of health-related behaviors in developing country contexts as individuals face substantial uncertainty about their own and other family members' health, t
SUBJECTIVE EXPECTATIONS AND HEALTH-RELATED BEHAVIOR
Autosomal recessive polycystic kidney disease (ARPKD) is an important genetic disorder in pediatric practice.  ARPKD is a renal and hepatic disease in neonates and infants, and <30% of affected neonates die because of greatly enlarged kidneys d
Intracellular calcium in the treatment of ploycystic kidney and liver diseases
SIGNIFICANCE: In the United States, it is estimated that one in seven women will develop breast cancer during their lifetime.  Estrogens are an important risk factor for the disease.  The timing of exposure also plays an important role in the d
Growth and Carcinogenic Potential in the Postnatal Mammary Gland
Prematurity, enteral formula feeding, and bacterial colonization are three major risk factors for neonatal necrotizing enterocolitis (NEC). The hallmark pathologic findings in NEC are intestinal mucosal injuries. However, the etiology and patho
BUTYRATE REGULATION OF INTESTINAL BARRIER
for the many time-invariant unobserved factors that present problems in the prior research. These fixed effects models utilize variation in outcomes for a single mother making factors, such as the quality of the school she attended, irrelevant
THE HEALTH CONSEQUENCES OF TEENAGE CHILDBEARING
To research how AMP-activated protein kinase management will improve oocyte cryopreservation.
AMP-ACTIVATED PROTEIN KINASE MANAGEMENT WILL IMPROVE OOCYTE CRYOPRESERVATION
Early events in the pathogenesis of interstitial pulmonary fibrosis (IPF) have been linked to faulty repair of injured alveolar epithelium where proliferating alveolar type II (AT2) cells do not effectively differentiate into type I (AT1) cells
Differentiation of Alveolar Epithelium and Pulmonary Fibrosis
Cigarette smoke (CS) is well known to induce chronic obstructive pulmonary disease (COPD) and cancer in humans. Cadmium is the most abundant toxic heavy metal that is present in CS. Cadmium is also present in contaminated air, food and water. C
(ARRA) Toxic metals and ion channels in cigarette-smoke induced COPD
Our goal is to analyze a range of disease severities. The database provides a unique resource to obtain a large number of multi-variate datasets for correlation analysis. The sample size in each subgroup is approximate, depending on data availa
Quantification of Regional Lung Disease by Computed Tomography - ARRA Stimulus Funding
Background: Interstitial lung disease (ILD) encompasses a broad range of chronic lung disorders. The mechanisms of pathogenesis for the development of this disease are mostly unknown. It is widely believed that genetic factors play an important
GENETIC ROLE OF EGFR PATHWAY IN INTERSTITIAL LUNG DISEASE
The goal of this proposal is to determine whether postnatal maternal care can moderate the effects of prenatal exposure to maternal stress on infant/toddler development. Accumulating data indicate that prenatal exposure to maternal psychosocial
Quality Of Maternal Care Moderates The Developmental Consequences Of Exposure To Prenatal Maternal Stress
We discovered mutations in the Senataxin gene (SETX) as the molecular basis of a juvenile-onset, autosomal dominant (AD) form of familial amyotrophic lateral sclerosis (ALS). This form of ALS, known as ALS4, is an essentially pure motor systems
SENATAXIN MUTATIONS IN FAMILIAL MOTOR NEURON DISEASE (ALS4) AND ATAXIA (AOA2)
Gene profiling of nervous system regeneration using a novel model organism Post-traumatic regeneration of neurons and fibers in the mammalian spinal cord has not been plausible, even though extensive studies have been made to understand the res
Gene Profilling of Nervous System Regeneration Using a Novel Model Organism
Chordomas are rare, slow-growing, malignant sarcomas that originate from notochordal remnants along the axial skeleton. Molecular mechanism of chordoma development remains unknown. Intriguingly, tuberous sclerosis complex (TSC) is the only know
Non-enveloped viruses breach the formidable cell membrane and deposit their infectious nucleic acid in the appropriate cellular compartment, a process known as 'cell entry.' Mechanisms of entry for non-enveloped viruses are not well understood,
Temperature-dependent, Intermediate Particles from the Entry of Picornaviruses into Host Cells
Dental caries and periodontal diseases are typical polymicrobial diseases, in which the pathogen(s) is also a member of the normal flora, which becomes pathogenic when the ecological balance of the commensal and pathogen is shifted toward overg
DEVELOPMENT OF A GENETIC SYSTEM IN VEILLONELLA
Electrochemically assisted sol-gel processing provides a route to deposit silica films with thicknesses in the range 10-200 nm, on electrodes.  These films are non-conductive and therefore passivate the electrode.  To impart conductivity we wil
SOL-GEL BASED NANOARRAYS FOR ELECTROCATALYTIC AMPEROMETRIC DETECTION OF PHOSPHOLI
Candidiasis now represents the third most frequent nonsocomial infection in hospitals both in the US and worldwide, and C. albicans remains the most frequent causative agent of cadidiasis.   Unfortunately these infections carry unacceptably hig
Candida Albicans Biofilm Dispersion as a key step during candidiasis
Rationale: Hepatic Scavenger Receptor Class B, Type I receptor (SRBI), a highly glycosylated 82 kDa protein, is primarily responsible for hepatic cholesterol ester uptake from high density lipoproteins (HDL), a process termed Reverse Cholestero
MODULATORS OF ALCOHOLIC LIPIDEMIA & STEATOSIS: KEY ROLE OF SCAVENGER RECEPTOR B1
Heavy episodic drinking (HED) among college students is a persistent public health problem with severe consequences, including development of substance-use disorders, psychosocial problems, health risks, accidental injuries, and death. National
BASICS-ED: A MOMENTARY INTERVENTION FOR CONCURRENT SMOKING AND HEAVY DRINKING
This application requests R21 exploratory funds to develop methodology and tools leading to a comprehensive registry of biomarker and health variables found in publicly available secondary data collections. The proposed pilot will begin with da
CREATING A BIOMARKER REGISTRY FOR SECONDARY DATA COLLECTIONS
In many age-related neurodegenerative diseases, neuronal loss is correlated with the presence of hyperphosphorylated tau. In Alzheimer's disease, it has been hypothesized that neurons die because cell cycle mechanisms have been activated. In su
TEC, rather than aged TEC. The long-term goal of the studies is to develop pre-clinical models for reversal of age-related thymic involution by transplantation of TEC progenitors derived from murine embryonic stem cells (mESC). Within the cons
STEM CELL-MEDIATED REVERSAL OF THYMIC INVOLUTION INPREMATURE AGING MODELS
Aging is accompanied by a decline in immune responsiveness that renders older adults highly susceptible to infectious diseases, and immunization vs. vaccine preventable illness such as influenza is less effective in seniors. A recently identifi
Aging, Immunization, and TH17 Immunity in Host Defense
DESCRIPTION: An emphasis in recent Alzheimer's disease (AD) research is identifying features and avenues for early intervention in the preclinical state of AD. Advanced imaging methods that enable visualization of AD associated brain changes a
ARRA AD classification algorithms using ADNI multi-modal image data
The purpose of this R21 application is to explore the feasibility of using bacteriophage resistance as a feature of a live, attenuated, oral Listeria monocytogenes vaccine delivery platform. We are studying a phage resistant mutant in which a T
Systemic lupus erythematosus (SLE, lupus) is a complex systemic autoimmune disease characterized by various immunological abnormalities, including an imbalance between type 1 and type 2 T cells that contributes to skewed cytokine production. Th
Protein kinase A-dependent regulation of T cell accumulation in Lupus
While most acute infectious diarrheas are self-limited, a subset requires aggressive treatment in order to minimize complications and/or prevent spread. Upon presentation, it is virtually impossible to know whether a diarrheal illness will have
Disposable Microfluidic Devices for Point of Care Diagnostics
Interleukin 13 (IL-13) is a pleiotropic, anti-inflammatory cytokine produced mainly by activated Th2 T cells. We have recently cloned a naturally occurring mRNA splice variant of IL-13 in which the second exon is omitted (termed IL-13?E2). Our
A NOVEL SPLICE VARIANT OF INTERLEUKIN-13 AND ITS ROLE IN PROMOTING EAE RESPONSES
Mycoplasma genitalium is a newly recognized cause of reproductive tract disease syndromes, including urethritis, mucopurulent cervicitis, pelvic inflammatory disease, endometritis, preterm birth, with possible sequelae that include infertility,
The broad long term goal of this project is to empower women to protect themselves from HIV infection through the development of improved microbicides based on sustained release drug delivery. Each day 15,000 people are infected - a growing maj
VAGINAL RING FROMULATION OF TENOFOVIR MICROBICIDE
Pathogenesis of HCV in a Novel Mouse Model - ARRA All current mouse models allow only HCV replication in the absence of a functional immune system. Those models are not useful to study host immune responses, their contributions to HCV pathogene
Pathogenesis of HCV in a Novel Mouse Model - ARRA
Cytokines produced by CD4+ T lymphocytes play essential roles in host adaptive immune responses and are involved in the development of allergic diseases including asthma. Our understanding of the pathways regulating cytokine production in CD4+
A NOVEL PATHWAY REGULATING CYTOKINE PRODUCTION & ASTHMA DEVELOPMENT
The high prevalence of nosocomial infections by multidrug-resistant Enterococcus faecalis presents both a treatment and an infection control challenge in the hospital setting. There is a clear demand to control enterococcal multi-drug resistanc
(ARRA) Eukaryotic-type STK/STP-mediated modulation of enterococcal pathogenesis
The long-term goal of our research is to understand how the RNAi mechanism affects HIV-1 viral replication.  RNA interference (RNAi) is a regulatory mechanism conserved in higher eukaryotes. The RNAi pathway generates small interfering RNA (siR
HIV-1 TAR derived miRNA:Implications for Latency & Pathogenesis
This proposal is to study the biological significance of IgE isoforms in allergic disorders.   IgE plays.a major role in allergic disorders, including asthma, atopic dermatitis.  We focus on a specific form of IgE believed to be responsible for
Alternative IgE Isoforms in Mast Cell Function and Immune Response
A novel approach is proposed to develop a cholera subunit vaccine based on the current understanding of Vibrio cholerae (Vc) colonization, pathogenesis, and the human immune response to cholera. Currently, a killed, whole-cell (W-C) Vc vaccine
A novel cholera subunit vaccine based on 4 colonization factors
DESCRIPTION (provided by applicant): The growing pandemic of type 2 diabetes (DM) is being increasingly recognized as a threat to tuberculosis (TB) control. Epidemiological studies consistently show DM patients are more susceptible to TB, but t
UNCONTROLLED DIABETES, IMMUNE DYSREGULATION AND TUBERCULOSIS
A suite of synchrotron-based x-ray imaging methodologies will be used to assess the development of crystalline biofilms formed by Proteus mirabilis in urinary catheters. Proteus is an extremely common pathogen in urinary tract infections, and i
Synchrontron Imaging of Crystalline Biofilms in Urinary Catheters
The hepatitis C virus (HCV) is an important pathogen that has infected approximately 170 million people worldwide. In spite of extensive efforts, surprisingly little is known about the mechanism by which HCV initiates infection. The lack of vac
Functional Characterization of the Hepatitis C Virus E1-E2 Glycoproteins
The development of a safe and effective topical microbicide to prevent the sexual transmission of HIV could playa major role in worldwide reduction of the over 14,000 new HIV infections per day, and potentially save millions of lives. The goal
Aggregatibater (Actinobacillus) actinomycetemcomitans is the etiologic agent of localized aggressive periodontitis and other systemic infections including infective endocarditis.  A. actinomycetemcomitans produces an RTX toxin, leukotoxin (LtxA
Many important diseases, including malaria, hepatitis and AIDS, could be eliminated by successful vaccines. However, such vaccines are elusive. This project aims to develop a new approach to making vaccines more effective. Our research has reve
NOVEL REVERSE ADJUVANT FOR VACCINE ENHANCEMENT
Our central hypothesis is that the interaction between HIV-1 integrase (IN) and the cellular co-factor LEDGF/p75 is important for efficient viral replication. We further hypothesize that inhibitors of this interaction have antiviral activity, a
Inhibition of HIV-1 Integrase-LEDGF/P75 Interactions
Modeling HIV-1 Eradication Therapies in the hu-Rag2-/-gamma c-/- Mouse Model - A  Latently infected memory CD4+ T cells constitute a major reservoir of persistent HIV-1 infection and are a central obstacle to its eradication. Agents must be dev
Modeling HIV-1 Eradication Therapies in the hu-Rag2-/-gamma c-/- Mouse Model - A
DESCRIPTION (provided by applicant): HIV induces a progressive and often irreversible deterioration of the immune system. Through years of experimentation and observation, we have learned that immune responses to HIV do exist and have a range o
MODULATION OF SURFACE MARKERS BY HIV-1 VPU/VPR AND SENSITIVITY TO NK CELL LYSIS
The g134.5 protein, present in herpes simplex viruses (HSV), plays an essential role in viral virulence.   Unlike wild-type virus, HSV mutants that lack the g134.5 gene are incapable of replicating and causing diseases. However, the underlying
Evident in its name, Helicobacter pylori is a helical bacterium that colonizes the human stomach causing clinical outcomes that range from mild gastritis to peptic ulcer and gastric cancer. We discovered genes that promote spiral shape by this
The Role of Cell Shape and Cell Wall in Helicobacter Pylori Pathogenesis
MicroRNAs (miRNAs) are genomically-encoded small RNAs (~ 21 nts) that bind to target mRNAs in a sequence-specific manner to regulate their translation and/or decay. In addition to its role in regulating cholesterol and fatty acid metabolism, th
(ARRA) Catalytic inactivation of miRNA function by customized RNase P-based ribozymes
With Malaria as a major global health burden, the emergence and spread of antimalarial resistance presents a significant threat to control efforts. The genetic basis of drug resistance is not completely understood. We need new approaches to ide
Forward genetic screens for identifying antimalarial resistance genes
Dengue virus is a mosquito-transmitted pathoghen that causes millions of cases of severe disease worldwide every year because there are no vaccines to prevent dengue infection and no antiviral medications to treat dengue disease.  A newly-disco
This R21 exploratory / development grant is being used to determine how the cellular ubiquitin-proteasome system interacts with coronaviruses.  Coronaviruses are common respiratory pathogens capable of causing severe epidemic disease.  We disco
Ubiquitin and cellular factors in coronavirus assembly
The mucosal immune system must remain tolerant to commensal bacteria and food antigens, yet still maintain the capacity to trigger inflammatory responses to pathogenic microorganisms.  The process of initiating inflammatory adaptive immune resp
Mucosal dendritic cell function following enteric virus infection
Cystic fibrosis (CF) is an inherited lung disease characterized by mucus hypersecretion, reduced mucociliary clearance of inhaled bacteria, particularly Pseudomonas aeruginosa (PA), and chronic airway inflammation. While the exact molecular mec
Counter-Regulation of TLR-Driven Mucosal Inflammation
This project examines the enhanced immunological protection in the lung that is associated with pre-existing iBALT (inducible bronchus-associaed lymphoid tissue) structures in the lung. The focus of the research will be on the enhanced B cell d
Tuberculosis(TB), caused by the organism M.tuberculosis (Mtb), kills more than 2 million people  worldwide every year(1). Our limited understanding of how vaccine responses mediates protection in the lung remains a major hurdle to successful va
Impact of Mucosal Immunization on Generation of Protective Lung-Resident IL-17 Producing Memory T Cells Against Turberculosis
The major functions of the gut epithelial compartment in a complex organism is to provide a protective barrier from pathogenic organisms that gain entry through the GI tract as well as facilitate the absorption and distribution of needed nutrie
INNATE IMMUNE LYMPHOCYTES AND THE GUT EPITHELIUM
The clinical success of macrolide antibiotics has been curbed due to the spread of resistance. One of the major resistance mechanisms found in pathogenic strains is the modification of the drug-target, the ribosome, by Erm methyltransferase enz
Mechanism of Induction of erm Genes by ketolide Antibiotics
In the early stages of Mycobacterium tuberculosis (Mtb) infection, irreversible tissue necrosis occurs as the result of localized lung inflammation. The bactericidal mechanism of macrophages and neutrophils, that are supposed to control the inf
Prevention of oxidative stress decreases persistence of drug tolerant M. Tubercu
ROSALIND FRANKLIN UNIVERSITY OF MEDICINE AND SCIENCE
DESCRIPTION (provided by applicant): Leishmania spp. are favorably considered as a universal carrier for vaccine delivery, since they have evolved not only an innate ability to infect antigen-presenting cells (APC) but also to reside exclusivel
TOWARD SUICIDAL AUTOMATION OF PORPHYRIC LEISHMANIA FOR PHOTODYNAMIC VACCINATION
Hepatitis C virus (HCV) infection is a major public health problem, putting infected individuals (~180 million worldwide) at risk of developing cirrhosis, hepatocellular carcinoma, and liver failure. Chronic hepatitis C is the leading cause for
ISOLATION OF GENETIC SUPPRESSOR ELEMENTS AGAINST HEPATITIS C VIRUS
Chronic rhinosinusitis (CRS) is one of the most prevalent chronic diseases in the USA but its pathophysiology is not well understood. Proinflammatory mediators and immunoreactive products likely play a significant role in initiating and sustain
Impact of Inflammatory Genes on Glandular Hyperplasia in Children with Sinusitis
Basic biomedical research to understand the function of T lymphocytes. These are the central regulatory cell of the immune system, the part of our body that fights off viruses, pathogenic bacteria, and parasites. The grant is entitled 'A quanti
Quantative Understanding of Regulation of Actin Dynamics in Live T Cells - ARRA Stimulus Funding
Toxoplasma gondii is an important opportunistic infection of AIDS patients. Improved strategies and approaches are urgently needed to more effectively prevent and treat recurrent opportunistic infections in AIDS. Toxoplasma gondii is also being
Genetic models for post-genome functional analysis of Toxoplasma gondii
The overall goal of this application is to understand biochemical mechanisms that underlie the function of rhesus monkey TRIM5 (rhTRIM5). rhTRIM5 blocks HIV-1 infection by acting at two or more post-entry stages. Importantly, rhTRIM5 E3 ubiquit
Regulators and Mediators of Trim5 Function
Fibromyalgia (FM) is a pain disorder defined by chronic widespread pain and multiple muscle-tendon junction tender points. Exercise has been suggested as a treatment for FM. Several exercise interventions in FM have demonstrated that patients w
THE NEUROENDOCRINE AND INFLAMMATORY RESPONSE TO EXERCISE IN FIBROMYALGIA
Atherosclerotic cardiovascular disease is the main cause of the long observed early mortality in rheumatoid arthritis (RA) patients. In this project, the possibility that the RA shared epitope (SE) is directly contributing to atherosclerosis de
MHC CLASS II-ASSOCIATED ENDOTHELIAL DYSFUNCTION
The primary goal of this COBRE proposal is to increase the number of active, NIH-funded biomedical researchers in the State of Delaware. This will be accomplished through the efforts of a multidisciplinary group of investigators at the Nemours
The purpose of this supplement request is to expose undergraduate minority students to research being conducted on cancer, including transcription factors, nutrition and cancer, as well as genomics and cancer.  Selected students will be 'piggy-
This project seeks to strengthen research collaborations between Montana State University and clinicians affiliated with the University of Washington Institute of Translational Health Sciences and to advance effective means to conduct systems b
Center for the Analysis of Cellular Mechanisms and Systems Biology
DESCRIPTION (provided by applicant): The specific Aims of the Nathan Shock Center (NSC) at the University of Michigan (UM) are to: (i) facilitate and stimulate research programs in the cellular and molecular biology of aging; (ii) encourage the
We request an administrative supplement to our grant P30 AG017253 to augment our research on the trends in demography, economics, health and healthcare of the aging.  This administrative supplement will enable expanding the approaches used in o
Center on the Demography and Economics of Health and Aging
Dana Farber/Harvard Cancer Center (DF/HCC) is an inter-institutional research enterprise that unites the major clinical, population, and basic cancer research efforts of the Harvard medical and public health community. It was founded in 1998 th
Memorial Sloan-Kettering Cancer Center is requesting 2 years of support for the recruitment of physician-scientists; one in the areas of translational oncology, who will be appointed to our Human Oncology and Pathogenesis Program (HOPP), and on
Our Cancer Center agrees to participate in the planning activities  associated with the  project entitled ADOPTion of New Technologies for Remote Data Capture and Protocol  Authoring (ADOPT) by providing appropriate clinical and informatics exp
ARRA ADOPTion of New Technologies for Remote Data Capture and Protocol Authoring
The goal of this proposal is to introduce high school and undergraduate students from all segments of the population to state-of-the-art cancer research and encourage the pursuit of cancer research as a career.  This is the best way to increase
Cancer Center Support Grant (Comprehensive)
To recruit a new faculty member to enhance the acute myeloid leukemia research program in the area of leukemia stem cell biology and targeted therapeutics.
This supplement was awarded to provide research support for a newly recruited physician scientist.   This new faculty member has  the primary goal of establishing a translational research program that will lead the way in developing new therape
The Cancer Center will participate in planning activities associated with project ADOPT by providing the clinical and informatics expertise of two staff members in scheduled meetings and conference calls for the duration of the project period.
The University of Minnesota Cancer Center (UMCC) is a NCI-designated Comprehensive Cancer Center dedicated to cancer research, education, and patient care for the citizens of the state of Minnesota and surrounding region. Since the time of the
Cancer Center Support Grant ADOPT Supplement
The Cancer Epidemiology and Prevention Program was formally established in 1973 when the New Mexico Tumor Registry joined with 6 other population-based tumor registries to form the NCI-SEER (Surveillance, Epidemiology and End Results) program.
UNIVERSITY OF NEW MEXICO CANCER CENTER SUPPORT
Creating links between established researchers and aspiring scientists at the early college level is especially crucial to teach students skills necessary for research, to expose them to an enriching scientific environment, and to connect them
The proposed Rocky Mountain Taste and Smell Center (RMTSC) will encompass twelve principal investigators including scientists with a substantial record of accomplishment in the field of chemical senses as well as investigators with expertise in
NIDCD P30 Core: Rocky Mountain Taste and Smell Center
(ACC) proposal also associated with P30 DC04661.
CORE CENTER--NIDCD RESEARCH CORE CENTER P30
This Core Center supplement has allowed us to hire a systems analyst-programmer who would accelerate both ongoing and future research projects by overcoming limitations in our locally developed data-collection and database software. A significa
'Core support for hearing research'This supplement, will stimulate the economy by enabling hiring of additional programming staff for a period of two years. This new hire will increase the pace of science in the P30 Center by 1) allowing center
, as well as two scientific symposia each year. The minisabbatical program supports travel of HDDC members to other institutions to learn new techniques. The HDDC pilot-feasibility grant program is highly subscribed and funded to the maximum le
Integrated Epithelial and Mucosal Biology
The Center for the Study of Inflammatory Bowel Disease (CSIBD) is a multidisciplinary program to define fundamental mechanisms underlying Crohn?s disease and Ulcerative colitis. This Center encompasses seventy-two investigators at the Massachus
Center for the Study of Inflammatory Bowel Disease
This project will address the role of adenovirus infection in the pathogenesis of asthma and cystic fibrosis
Molecular therapy for CF and genetic diseases
The CNRU of Maryland will focus on the influence of nutrition and exercise on risk for age-related chronic diseases, including obesity, type 2 diabetes, hypertension, cardiovascular disease (CVD), sleep disordered breathing, and osteoporosis. W
Clinical Nutrition Research Unit of Maryland
Supplemental funds for equipment purchases are requested to increase the tempo of scientific research funded under our parent grant, P30HD024061 which supports the Intellectual and Developmental Disabilities Research Center (IDDRC) of the Kenne
Mental Retardation and Developmental Disabilities Research Centers 2008
Project Description (3830 characters with spaces) The project provides further support for 3 Cores of our Intellectual and Developmental Disabilities Research Center (IDDRC). The usage of the Cellular Imaging, Molecular Genetics and Neuroimagin
MRDDRC at Children's National Medical Center
The supplement has funded the establishment of an SIV/Macaque Research Core which will provide the expertise to evaluate novel therapeutics and surrogate markers to develop new therapies for HIV-associated neurocognitive disorders. The investig
CENTER FOR NOVEL THERAPEUTICS FOR HIV ASSOCIATED COGNITIVE DISORDERS-ANIMAL CORE
We have made significant progress towards Aim 1. In particular, we have tested the hypothesis that CtIP could physically interact with the Mre11-Rad50-Nbs1 complex. Using cell-free extracts that are virtually devoid of DNA, we immunoprecipitate
Center for Evidence-based Practice in the Undeserved (CEBP)
The principal goal of this application is to use the integrated units of the CPRC to provide science educators and their students the opportunity to engage in basic biomedical and behavioral research using the resources of the CPRC.  This will
CARIBBEAN PRIMATE RESEARCH CENTER PROGRAM
In this application, we propose a comprehensive National Gene Vector Repository (NGVB) which meets all the goals stated in RFA-RR-07-002.The Specific Aims of the NGVB are: Specific Aim 1. Develop and Oversee a Repository of Gene Therapy Reagent
National Gene Vector Biorepository and Coordinating Center at Indiana University - P40 NGVBCC #1
This Resource develops and uses Multi-isotope Imaging Mass Spectrometry (MIMS), the combination of a novel type of secondary ion mass spectrometer with tracer methods and intensive quantitative image analysis. MIMS provides high mass separation
National Resource for Imaging Mass Spectrometry.
We will provide for the research community a classification and representation of cell types. We will refine the terminology for cell types, and provide logical definitions for all terms.  This project will extend the ability of biologists to s
Mass spectrometry has become the enabling tool for identification of both lipids and proteins and fordetermination of their structures and properties. The changes in lipids with disease have becomeincreasingly recognized, suggesting they may be
A RESOURCE FOR BIOMEDICAL MASS SPECTROMETRY
Fast and reliable intra-operative diagnosis is a critical component of successful oncological surgery in a variety of organ systems. While optical probe and in vivo imaging strategies have been proposed by us and others as potential tools for s
The original P41 established the NCRR Integrated Technology Resource for Biomedical Glycomics at the University of Georgia to develop and implement new technologies to investigate the glycome of cells and exploit the use of these technologies t
Integrated Technology Resource for Biomedical Glycomics
The University of Kentucky is unique among land grant universities in that all colleges, including Medicine and Agriculture, are located on the same campus. This constellation of programs has enabled the UK-SBRP to develop uniquely productive c
Nutrition and Superfund Chemical Toxicity Summer Supplement
This supplemental funding will provide support for a collaboration between Boston University's Superfund Basic Research Program Outreach Core and Brown University. The Boston University Superfund Research Program is an interdisciplinary program
Superfund Basic Research Program at Boston University
This funding will allow us to promote job creation and economic development as it accelerates the pace and achievement of the scientific research as outlined in our parent grant, one of the seven NIH-funded Transdisciplinary Tobacco Use Researc
Building the Evidence Base for Tobacco Control Policies
The Centers for Population Health and Health Disparities (CPHHD) were funded by NIH in 2003 to address social, behavioral, and biological/genetic determinants of health disparities.  The eight centers collaborated previously on a joint project
CENTER FOR INTERDISCIPLINARY HEALTH DISPARITIES RESEARCH
We are particularly enthusiastic about the unique opportunity with this administrative supplement to both retain jobs and advance the tempo of our scientific research within the University of Washington NIEHS/NSF funded Pacific Northwest Center
PACIFIC NORTHWEST CENTER FOR OCEANS AND HUMAN HEALTH
This administrative supplement will support ongoing research undertaken by Dr. Elba Serrano's NMSU team of students and professional scientists as part of the current Cell Decision Process award.  The long term goal of this research is to uncov
Systems Biology of Cell Decision Processes
The Colorado Learning and Disablities Research Center (CLDRC) consists of an Administrative Cores and Five Component Projects that focus on the identification, characterization, validation and amelioration of reading disabilities (RD) and ADHD,
Differential Diagnosis in Learning Disabilities - Project III
as outlined in PA 03-004. The first project examines functional differences between dopamine (DA) neurons in the substantia nigra (A9) that are vulnerable to PD compared to those spared in the same midbrain tissue region A10 (VTA). We discover
Novel Therapeutic Approaches for Parkinson's Disease
Argatroban, a thrombin inhibitor, has been studied in the setting of both coronary perfusion as well as acute ischemic stroke. Since the majority of ischemic stroke patients may not benefit from rt-PA alone, the combination of thrombolytics wit
A PILOT STUDY TO DETERMINE THE SAFETY OF ARGATROBAN INJECTION IN COMBINATION WITH
The purpose of this administrative supplement is 3-fold: 1) to increase access for our acute stroke patients,  2) to accelerate scientific discovery in 3 internal SPOTRIAS and 3 consortium-wide SPOTRIAS clinical research studies.   3) to stimul
New York Columbia Collaborative SPOTRIAS-Core A
This is a Pilot Project Fund from which funding is targeted toward junior faculty at the Instructor and Assistant Professor levels. The aims of the program are to: 1) accelerate the acquisition of critical proof-of-concept data; 2) provide a va
New England Primate Research Center Base Grant
The transition from being a scientist 'in training' to being an independent researcher is typically a difficult one.  We are proposing to add depth to our existing Pilot Research Program by targeting postdoctoral researchers who would normally
Subproject for Institution # 790404: CALIFORNIA NATIONAL PRIMATE RESEARCH CENTER
During this last funding period, the ARC Laboratory Core has developed a state-of-the-art FACS facility.  In addition to our previously existing FACSCalibur flow cytometer, the Core acquired 3 top model FACS pieces of equipment.  These new addi
Previous research published in this laboratory in Cell in 2008 (McAllister, SS et al., Cell 133:994-1005) described a process that was termed “systemic instigation” in which a vigorously growing “instigating” tumor implanted in one side
Mechanisms of Breast Development and Carcinogenesis
expression following encounter with antigen, and that CD8+ T cells expressing NK cell receptors persist in chronically infected mice but not in mice that clear the infection. These receptors included members of the KIR family, as well as of th
Anergizing effect of NK cell receptor expression on HIV-specific CD8+ T cells
Research project: In vertebrates, sensory neurons of the parasympathetic epibranchial (EB) ganglia derived from ectodermal placodes are essential for the formation of cranial sensory systems such as smell, somatosensation, and taste. Despite th
DEVELOPMENT OF EPIBRANCHIAL PLACODES AND GANGLIA IN ZEBRAFISH
This is an application for competitive revision of the currently active RO1 grant 'Short-Chain Dehydrogenases (SDRs) in Retinol/Sterol Metabolism' submitted in response to the Notice NOT-OD-09-058: NIH Announces the Availability of Recovery Act
SHORT-CHAIN DEHYDROGENASES IN RETINOL/STEROL METABOLISM
The purpose of the supplemental funds is to purchase an automated fear-conditioning system and place it within our laboratory space where we can have access to it, just like the other behavioral equipment.  This purchase would be an investment
Prenatal Alcohol: Hormone-regulated Genes and Behavior
The overall goal of this supplement to R01AA014356 is to develop and test the remote telephone delivery of a successful intervention that reduces drinking and improves contraception among women at risk for alcohol-exposed pregnancy due to frequ
The neurochemical and cellular mechanisms that contribute to the control of ethanol drinking behavior are not fully understood, but the involvement of dopamine in the mesolimbic system has been hypothesized for some time. Many neurochemical sys
MU RECEPTORS AND ETHANOL/DOPAMINE INTERACTIONS
Administrative Supplement Notice for Students and Science Educators under the  Recovery Act; NOT-OD-09-060. The purpose of this award is to support a middle school teacher, Todd Martin, during temporary employment during the summer months with
CTGF in pancreatic stellate cell-mediated fibrogenesis
The overall goal of the proposed studies is to delineate a mechanism responsible for impaired intestinal immunity and barrier function following EtOH intoxication and burn injury. This administrative supplement award is to generate new summer j
Alcohol Intoxication and Postburn Intestinal Immunity
UNIVERSITY OF TEXAS M.D. ANDERSON CANCER CENTER, THE
Critical issues for improving the treatment of alcoholism are what neurobiological changes are responsible for the transition from non-dependent alcohol use to alcoholism, and what persistent changes mediate relapse. The goals of the present pr
BRAIN BIOMARKERS OF ALCOHOLISM AND ABSTINENCE
Neuroanatomical alterations in Alzheimer disease. Alzheimer disease (AD) dementia affects 1 in 10 American families, and costs more than 90 billion dollars a year. Genetic and neuropathological evidence highlight a pathogenic role for Abeta, bu
Neurologic Alterations in Alzheimer's Disease
The parent grant continues to have three aims. The first is to elucidate how the molecular chaperones BiP and GRP94 react to misfolded Ig in the cell and how this interaction can be employed to reduce the aggregation that leads to amyloid form
Immunoglobulin Structure, Stability and Aging
The VETSA Longitudinal Twin Study of Cognition and Aging is a unique project that provides a comprehensive prospective examination of genetic and environmental influences on cognitive and brain aging with extensive data from neurocognitive, hea
THE VETSA LONGITUDINAL TWIN STUDY OF COGNITION AND AGING
The parent project aims at deciphering the molecular pathways supporting satellite cell function and at understanding how these are influenced during aging. Age-related skeletal muscle deterioration (sarcopenia) is characterized by a decline in
Myogenic Stem Cell Function in Aging Skeletal Muscle
This competitive revision application to grant R01AG029546 is submitted in response to NOT-OD-09-058: NIH Announces the Availability of Recovery Act Funds for Competitive Revision Applications. This revision proposes to add optical brain imagin
Modeling Sensory Integration and Attention in Postural Control of Older Adults
DESCRIPTION (provided by applicant): A recently recognized role of nicotinic acetylcholine receptors (nAChR) is to regulate inflammatory cytokine expression. As we age, changes in nAChR expression are observed and these correlate with dysregula
PERIPHERAL NICOTINIC CHOLINERGIC AND INFLAMMATORY DYSFUNCTION IN AGING
In the parent grant 1R01AG031136 entitled 'Identifying and characterizing protein quality control mechanisms in the nucleus' we described three aims: (1) determine the regions within San1 responsible for substrate targeting; (2) determine the f
Identifying and characterizing protein quality control mechanisms in the nucleus
The overall goal of this administrative supplement is to accelerate research concerning replenishment of the immune system in adults.  Specifically, newly developed reporter mice are being exploited to chart developmental pathways between hemat
Early Events in Mammalian B-Cell Differentiation
Abstract:  A major goal of the parent award was to understand the mechanism of replication of hepatitis delta virus (HDV). In most of the ways in which we study the replication of the small circular RNA of HDV, we are actually detecting the acc
Structure and Replication of Hepatitis Delta Virus
MCH is a major part of adaptive immune system.  Thus, understanding the ancestral synteny of MHC in more details might acquire new insights on the primordial MHC structures and mechanisms vital for a functioning immune system and further reveal
Both naive CD4+ and COB+ T cells are dependent on two types of signaling, from contact with IL-7 and self-MHC/peptide ligands, for their continued survival under normal conditions and to undergo homeostatic proliferation in response to lymphope
Regulation of T Cell Homeostasis and Survival
Eastern equine encephalomyelitis virus (EEEV) is a serious infection of humans, and is listed as a high- consequence select agent. In studies carried out during the previous funding period, we demonstrated that EEEV ecology in the mid- Southeas
Ecology of Encephalitis Viruses in the USA
Immune control of HIV-1 is dependent on the migration of HIV-1 specific CTLs towards and colocalization with infected cells. This process is orchestrated by the action of chemokines serving as chemoattractants at sites of infection. We recently
HIV-1 gp120 Induced CTL Chemorepulsion: Dysregulation of Migration & Localization
Membrane fusion, a process critical for viral entry, is promoted by the paramyxovirus fusion (F) proteins. All F proteins contain a number of common features that play fundamental roles in fusion. However, significant variations exist between F
Paramyxovirus F Protein Mediated Membrane Fusion-Admin Summer Supplement
Overview: Although there is consensus that HIV accelerates hepatitis C (HCV) disease in co-infected (HIV+HCV+) patients, studies differ regarding the impact of HCV infection on HIV disease progression. This proposal seeks continued support for
HCV and HIV Progression in Women on HAART
This project seeks an administrative supplement to support an undergraduate summer student to work in the Glickman lab in the summer of 2010.  The student was recently identified.  The funding of this supplement will both accelerate the pace of
Cyclopropane synthetases and M. tuberculosis Virulence
Reservoirs of drug-resistant HIV-1  --  Antiretroviral drugs have radically modified the course of HIV-1 disease among individuals with access to these chemotherapeutics. The selection of drug-resistant viruses, however, can markedly foreshort
This project's goal is to use a well-characterized model system to define processes governing the formation and activity of CD4+CD25+Foxp3+ regulatory T (Treg) cells. The proposal will make use of existing lineages of transgenic mice expressing
Specificity and Function of CD25+ Regulatory T Cells
Retroviruses have devised a number of strategies to evade cellular mechanisms aimed at preventing retroviral infection. HIV-1 expressesVif, a protein that counteracts the antiviral activity of the cytidine deaminases APOBEC3G and APOBEC3F. The
HIV-1 EVOLUTION DRIVEN BY INTRACELLULAR DEFENSES
The long-term aim of this proposal is to develop a technique that will enable highly automated, multi-functional epigenetic profiling of whole chromosomes from single cells. Such a technique will provide a tool for single-molecule studies probi
Epigenetic Profiling by Near-Field UV-Raman Scattering in Nanochannels
DESCRIPTION (provided by applicant): Persistence of cancer cells even after surgery and androgen-ablation therapy, their proliferation, androgen- independence and invasion to distant sites is the major cause of deaths in human prostate cancer p
ARRA Delaying the Hormone Refractory Prostate Cancer by a Dietary Triterpene Lupeol
individuals. In our preliminary study, we have constructed an ESCC T7 phage-display library from tumor tissues, and have biopanned this library with patient and normal sera to enrich tumor-associated proteins that bind to autoantibodies found
PROFILING AUTOANTIBODIES FOR EARLY DETECTION OF ESOPHAGEAL SQUAMOUS CELL CARCINOM
The goal of this study is to develop a systems-based intervention to increase the numbers of offers made to patients in order to increase the number of patients enrolling onto trial protocols.  We will test the feasibility and efficacy of a two
IMPROVING CLINICAL SYSTEM COMMUNICATION TO INCREASE TRIAL OFFERS TO CANCER PATIENTS
Although urokinase (uPA) and its receptor strongly contribute to the dissemination of prostate cancer, the efficacy of existing approaches to disable this system is incomplete, possibly because uPA acts through additional uncharacterized pathwa
Nuclear urokinase (uPA) regulates tumor cell proliferation and survival.
The proposed study will test the hypothesis through off-label use of commercially available imaging agents.  The rationale for this study is that a successful outcome would lay the foundation for future larger studies of functional ultrasound i
FUNCTIONAL ULTRASOUND TOMOGRAPHY: TESTING A LOW-COST BREAST IMAGING CONCEPT
The proposal seeks to develop the first meaningful objective radiographic parameter that correlates with the clinical symptoms of radiation pneumonitis (RP) as an imaging biomarker of RP. RP is the dose limiting toxicity in thoracic radiotherap
A PHASE II STUDY TO TEST THE CORRELATION OF A RADIATION PNEUMONITIS IMAGING BIOMA
We have just completed a Phase I dose/toxicity trial for children and young adults with recurrent solid tumors using 90Y-DOTA-tyr3-Octreotide (90Y-DOTATOC) to target the somatostatin receptor type 2 (sst2) expressed on tumor cells. Potential su
Dosimetry Guided Phase II of 90Y-DOTA-tyr3-Octreotide + Retinoic Acid in Kids
Prostate cancer is the most common cancer and the second leading cause of cancer death affecting men in the United States. Approximately 30% of men with detectable serum prostate-specific antigen (PSA) levels after curative radical prostatectom
Cocaine is a powerful psycho stimulant and one of the most addictive drugs of abuse. Despite decades of efforts, no effective pharmacological treatments have been developed for cocaine addiction or acute cocaine toxicity. There are two main app
(ARRA) Cocaine degrading enzymes from pest insects of coca plants
Marijuana use is among the most frequently used illicit substance among emerging adults (those between the ages of 18 and 25) which places them at high risk for a number of undesirable consequences.  Those who report recent frequent use (i.e.,
INDICATED MARIJUANA PREVENTION FOR FREQUENTLY USING COLLEGE STUDENTS
After the Hurricane Katrina disaster in August, 2005 a massive influx of Latinos from Mexico and Central America, mostly undocumented and unaccompanied by their families, came seeking construction work.  Post-disaster New Orleans is not only a
Epidemiology of Drugs and HIV Sex Risk Among Latino Migrants
Opioid abuse is a common problem in the United States. It is estimated that 2.4 million people in this country use heroin at some time in their lives. Addiction to heroin has several long-term consequences, including molecular changes in the br
Autonomous Treatment of Opioid Abuse AARA
Cue-induced craving is currently not well understood in nicotine dependence, and is a poor predictor of use. However, as with other drugs of abuse, studies suggest that craving measures become more relevant to drug use when the opportunity to u
fMRI Correlates of Olfactory and Visual Cues in Tobacco Smoking
Real-world experience and clinical research converge in demonstrating that substance-dependent individuals will continue to use drugs despite an often strong desire to cease taking them. This suggests that a cardinal characteristic of dependenc
Using rt-fMRI to Modulate Neural Responses to Drug and Nondrug Rewards in Cocaine Dependent Individuals
DESCRIPTION (provided by applicant): The Sigma-2 receptor is a unique protein found in most mammalian tissues. Sigma-2 receptors play an important role in growth regulation in normal cells and tumor cells of neuronal and non neuronal origin. Th
Characterization of the Sigma-2 Receptor
A large body of evidence suggests that ion channels act as force sensors in mechanotransduction systems. In flies, the No mechanoreceptor potential-C (Nomp-C) channel has been suggested to be a force transduction channel in neurons that detect
GENOME-WIDE ANALYSIS OF ION CHANNELS REQUIRED FOR MECHANOSENSATION
The long-term goals of the proposed research are to develop tissue-engineering materials (TEM) with enhanced biocompatibility, and flexibility to tailor mechanical properties for a wide range of applications. There are two specific aims for thi
Visible light-cured tissue engineering polymers filled with bioactive glass
The aim of this project is to develop a biopsychosocial model that explains how sociodemographic, biosocial, behavioral factors interact with one another to lead to differential oral health in later life. Oral aging indicators examined in this
Sociodemographic, Biosocial and Behavioral Mechanisms Linked to Earlier Oral Aging
The Role of Endogenous Cardiac Glycosides in Outcomes among African Americans with Hypertensive Kidney Disease. Chronic kidney disease (CKD) affects an estimated 19 million adults in the US and is associated with a higher risk of cardiovascular
Obesity has become the most common nutritional disorder in the developed world and the co-morbidities of obesity contribute significantly to mortality and medical costs throughout the world.  Biological or circadian rhythms have profound effect
Circadian Expression of Procolipase in the Liver: A Metabolic Signal
Masses of the pituitary gland (sellar masses) are common, representing approximately 15% of all intracranial masses. About half of the sellar masses are caused by a hormone-secreting adenoma and more easily diagnosed because of classical signs
A NEW SERUM TEST FOR THE DIFFERENTIAL DIAGNOSIS OF PITUITARY MASSES
Benign prostatic hyperplasia is one of the most common chronic conditions among America men. The traditional, `gold standard', surgical treatment is transuretheral prostatectomy (TURP). However, during the last decade the use of minimally invas
Measuring the Impact of the Rapid Expansion of MIST Procedures for BPH
Although the glomerulus has long since been known to be compromised of four resident cell types, the contributions of the endothelial cell, mesangial cell, and podocyte to glomerular architecture and function have garnered virtually all of the
NEW THOUGHTS ON PARIETAL EPITHELIAL CELLS
Increases in childhood obesity are a public health concern worldwide. In the U.S., 17.6 percent of adolescents have high BMIs for their age. Obesity early in life is associated with poorer physical and mental health and social wellbeing, includ
FRIENDSHIPS AND RISK OF OVER-WEIGHT AMONG DIVERSE-ORIGIN ADOLESCENTS
Diabetes causes lower extremity problems in a large number of diabetic patients. Peripheral arterial disease (PAD) can affect up to 29% of all diabetic patients while functional changes in the microcirculation are present in the vast majority o
THE EFFECT OF DIABETES, NEUROPATHY AND ARTERIAL DISEASE IN LOWER EXTREMITY ENERGY
Current below the knee (trans-tibial) prostheses utilize elaborate springs and elastomers to store and dissipate energy during ambulation. While these designs are functional, they do not allow for energy input into the system which is necessary
The objective of the award is to develop four SPNW sensors for four cardiac markers (myoglobin, BNP, c-TnI, and CK-MB) for rapid and accurate AMI diagnosis and prognosis.  In order to accomplish the objective, our specific aims include: (a) dev
Point-of-care system based on single polymer nanowires for real-time, AMI diagnos
DESCRIPTION (provided by applicant): Our ultimate goal is to develop a new and simple method to microencapsulate drugs and other bioactive substances, particularly biomacromolecules such as proteins and peptides, in biodegradable controlled-rel
Self-microencapsulation in polymer delivery systems without organic solvents
Protein-Cell Assemblies as Tissue Mimics It is proposed is to directly assemble living cells and recombinant structural proteins into tissue mimics for subsequent tissue regeneration, therapeutic screening, and other biomedical applications. El
fabrication techniques may lead to the engineering of performance protein fibers for many biomedical applications.
MICROSYSTEM-BASED FORMATION OF RECOMBINANT PROTEIN FIBERS
The prevalence of autism spectrum disorders (ASDs) has been increasing during the last 10 years with increasing burden on society. While genetic risk factors are widely implicated in ASDs, the current increase is not likely to result from genet
Investigating Gene-Environment Interaction in Autism: Air Pollution x
Nanotechnology,  the  use  of  nanomaterials  at  the molecular  level,  is  a multidisciplinary  scientific  field undergoing exponential growth and has broad applications among all divisions of science.  One form of nanomaterials,  fullerenes
Prevention of Allergic Disease Using Nanomaterials
Retinal degeneration is one of the leading causes of vision loss and blindness in the world. Some retinopathies are caused by autoimmune processes. Autoantibodies against retinal proteins are strongly associated with retinal degeneration in pat
TREATMENT OF AUTOIMMUNE RETINOPATHIES WITH ANTI-AGING POLYPHENOL RESVERATROL
HSV-1 infects half of individuals in the United States, and causes 400,000 new painful, sight-threatening eye infections each year. Our goal is to develop a prophylactic vaccine to prevent debilitating consequences of these infections.
Improving Vaccine Safety and Efficacy to Control Primary HSV-1 Infections
This study aims to evaluate a conceptual model that examines the role motor skill competence plays in influencing physical activity patterns of children, along with potential mediating factors of perceived motor competence and physical fitness.
(ARRA) Examining the dynamic relationship between motor competence and physical activity
The specific aims of the project included the following.     This project proposes new ways to analyze B-W mortality disparities in the U.S. between 1980 and 2005 by investigating the contribution of causes of death considered amenable by (1) h
Explaining Black-White Differences in Avoidable Mortality, 1980-2005
WINIFRED MASTERSON BURKE MEDICAL RESEARCH INSTITUTE, INC., THE
The present grant aims to achieve the following outcomes across the two-year funding period: 1. to evaluate whether Transcranial Direct Current Stimulation (tDCS) should be delivered sequentially or in parallel to motor training, to enhance mot
Transcranial Direct Current Stimulation and Motor Training in Chronic Stroke
Myocardial infarction (MI) is a leading cause of mortality in today's society. Injury to myocardium is a manifestation of the intrinsic cellular response to ischemia and of an extrinsic acute inflammation. Recent pre-clinical studies have revea
ARRA: The Role of Autoimmune Natural IgM in Human Myocardial Infarction
Blood damage caused by flow shear can cause thromboembolic complications that seriously limit the performance of a broad range of cardiovascular hardware including prosthetic valves, bypass pumps, and assist device. An attractive way to mitigat
ARRA: REDUCTION OF THROMBOEMBOLIC POTENTIAL IN CARDIAC DEVICES VIA PASSIVE FLOW CONTROL
DESCRIPTION (provided by applicant): Hypertension during pregnancy affects 5-8% of pregnancies in the United States and contributes to serious complications for both the fetus and mother. Hypertension may lead to pre-eclampsia, which can restri
The Impact of Sleep-Disordered Breathing on Adverse Pregnancy Outcomes
Documentation of cardiomyocyte cell cycle activity and myocardial tissue regeneration typically requires extensive histochemical processing and frequently relies on the use of subjective criteria for cell lineage determination. Although reporte
Transgenic Reporters for Cardiac Growth and Regeneration
DESCRIPTION (provided by applicant): The nucleus controls gene expression patterns that characterize the function of individual cells. Responses that occur in the nucleus, such as transcription and splicing of pre-mRNA, are elaborate processes
REVERSE TRANSCRIPTASE ACTIVITY IN MEGAKARYOCYTES AND PLATELETS
INTEGRATED RECALL OF DIET AND PHYSICAL ACTIVITY IN CHILDREN Information provided by parents about their children`s dietary intake and/or physical activity (PA) often is inaccurate because children eat meals and are physically active in location
INTEGRATED RECALL OF DIET AND PHYSICAL ACTIVITY IN CHILDREN
in an effort to stabilize vulnerable plaques. PUBLIC HEALTH RELEVANCE: In the United State, 3 people die from heart disease every minute with plaque rupture contributing to the majority of those deaths. Our data suggest that FcR signaling in i
ROLE OF MACROPHAGE ACTIVATION IN CAROTID PLAQUE INSTABILITY
This proposal is a substantial revision of application 1 R21 MH079984-01 which was reviewed October 11, 2006 by the Mental Health Services in Non- Specialty Settings review group. Goals, specific aims, and hypotheses have been clarified to be c
A RANDOMIZED EXPLORATORY STUDY OF TELEPSYCHIATRY OUTCOMES IN RURAL YOUTH
The Idaho Partnership for Hispanic Mental Health phase one planning project seeks to address the mental health service needs of Mexican immigrants in southwest Idaho through the development of a community-academic partnership.
Idaho Partnership for Hispanic Mental Health
Poor maternal dietary quality in the 1st trimester of pregnancy can alter the intrauterine nutritional environment and adversely affect placental development and subsequent fetal development and growth. The early months of pregnancy, when the p
Predictors of Dietary Quality in Low-Income Pregnant Women
Dementia, an age-associated clinical syndrome characterized by irreversible loss or decline in memory and other cognitive abilities, is a growing health problem. In 2008, an estimated 5.2 million Americans have Alzheimers disease (AD), which co
Excessive activation of ionotropic glutamate receptors increases oxidative stress, which contributes to the neurodegeneration observed following neurological insults such as ischemia and seizures, as well as contributes to neuronal death in neu
CHROMATIN MODIFICATIONS AND VULNERABILITY TO GLUTAMATE TOXICITY
Many neurodegenerative diseases, including spinal and bulbar muscular atrophy (SBMA) and ALS, result from protein misfolding and accumulation due to a variety of both genetic and environmental causes. SBMA is an adult-onset neuromuscular diseas
The control of every movement, whether it is a basic reflex or a sophisticated skill, is highly complex, involving the control of muscles distributed throughout the limb and body. This complexity is present whether movements are produced natura
Restoration of movement using muscle synergies to control natural limb dynamics
The project R21 NS 062669, entitled, “HIV-1 infection: Central Serotonergic Activity and its Health Implications”, investigates the hypothesis that HIV-1 infection impacts the central serotonergic system in different brain regions and that
HIV-1 INFECTION: CENTRAL SEROTONERGIC ACTIVITY AND ITS HEALTH IMPLICATIONS
Parkinson's disease (PD), the most frequent movement disorder, is caused by the progressive loss of the dopamine neurons in the midbrain in an area called substantia nigra pars compacta (SNc), resulting in a deficiency of the neurotransmitter d
Testing the efficacy of PGC-1alpha as a therapeutic target for Parkinson's disease by rAAV-mediated expression in MPTP-treated mice
Ischemic stroke is caused by cerebral blood flow (CBF) inadequate to allow brain tissue survival. It is known from humans treated with tissue plasminogen activator that ischemic tissue can be salvaged from infarction by thrombolytic CBF restora
S-NITROSYLATED HEMOGLOBIN & LSCHEMIC BRAIN INJURY
Tau is a natively unfolded protein that has been implicated in the pathogenesis of several neurodegenerative disorders such as Alzheimer's disease (AD). A number of studies suggest that aggregates of tau contribute to neuronal death and dysfunc
Structure-Based Ligand Design of Inhibitors that Prevent Tau Aggregation
Traumatic brain injury and stroke each affect millions of people yearly; aneurysmal subarachnoid hemorrhage patients suffer from both. Utilizing aneurysmal subarachnoid hemorrhage patients as model for these types of brain injury, it may be pos
Biochemical Markers in Adult Patients with Aneurysmal Subarachnoid Hemorrhage
Disorders of the central nervous system are often associated with little or no recovery due to in part to poor neural regenerative capacity, damaging mechanisms that persist after initial neuronal injury, and inhibitory properties intrinsic to
Localized Immobilization of Ephrin-B2 for Neurite Guidance on 3D Culture
The focus of this application is on abnormalities of TDP-43, a protein that underlies a number of neurodegenerative diseases (frontotemporal lobar dementia [FTLD], Parkinson's disease [PD], and amyotrophic lateral sclerosis [ALS]). In 2006, ubi
Several devastating diseases that are caused by nerve degeneration, including amyotrophic lateral sclerosis (ALS), have been unified by a common underlying theme: the clumping of a protein, TDP 43, in nerve cells. Our proposed studies aim to pr
Exploring mechanisms of TDP-43 aggregation and disaggregation
Proteomics is one of emerging tools for drug discovery and medical diagnostics.  Two-dimensional gel electrophoresis is one of the most potent methods in proteomics studies.  The goal of this project is to develop a lab-on-a-chip device that wi
Two-Dimensional Electrophoresis Device for Biomarker Detection
Current 2D and 3D deconvolution and analysis techniques are not well suited for deep tissue microscopy. Most assume the point spread functions (PSFs) to be symmetric or spatially invariant, which is not the case for thick samples. In addition,
Image Enhancement and Segmentation for Deep Tissue Microscopy
Over the last decade, ubiquitin has emerged to rival phosphorylation as one of the cell's most broadly utilized protein modifications, and it has become widely appreciated that ubiquitination serves critical regulatory roles in virtually every
Discovery of ubiquitin ligase substrates - the development of integrated experime
A Home based intervention for young children with intellectual disabilities in Vietnam.
As Defined in the Award Description Field
Diversity-promoting Institutions Drug Abuse Research Program (DIDARP) at the Graduate School of Public Health , aims to increase the instituion's drug abuse research capacity through mentored research experiences for faculty at different levels
DIDARP AT THE UNIVERSITY OF PUERTO RICO SCHOOL OF PUBLIC HEALTH
This early childhood obesity prevention study focuses on low-income and often minority families in a small city who have disproportionately high obesity rates. The interdisciplinary research team with expertise in childhood obesity, family deve
ARRA Funded:  A Childhood Obesity Prevention Program Designed by Families for Families
This one-year grant will support planning and protocol development for a 12-month, multi-center randomized trial in which older adults (ages 65 and older) with insomnia will be randomized to one of three treatment arms: 1) Zolpidem (Ambien); 2
Zolpidem and Cognitive Behavioral Therapy for Insomnia in Older Adults
Depression is one of the most prevalent and disabling psychiatric disorders, and evidence suggests that low-income Latinos may be at particularly high risk for experiencing the disorder. However, utilization of formal mental health services is
Latino Men and Depression: An Exploratory Study of Help-Seeking Behavior
Scholars have speculated about the role of historical and social factors in the changing profile of health disparities by gender and race; but have provided little empirical evidence with which to evaluate those speculations. I propose the firs
Untangling Racial and Gender Disparities in Health and Well-Being in the United States 1972-2008
Possible development of diagnostic products for Rheumatoid Arthritis. Specifically, these diagnostics will identify patients who have disease exacerbations due to Neu5Gc accumulation in joints from dietary sources combined with certain anitNeu5
N-GLYCOLYLNEURAMINIC  ACID IN THE PATHOGENESIS AND PROGRESSION OF RHEUMATOID ARTHRITIS
The goal of the proposed program is to address several technical feasibility questions (in Phase I), and then demonstrate (in a subsequent Phase II) incorporation of Sonetics' groundbreaking CMUT-in-CMOS ultrasound transducer technology into a
COMMERCIALLY VIABLE WIDE-BAND ULTRASOUND ARRAYS BASED ON CMUT TECHNOLOGY
Electromedical and Electrotherapeutic Apparatus Manufacturing
Natural Killer T (iNKT) cells represent a lymphocyte population that has evolved to recognize glycolipid antigens presented by CD1d. Upon recognition of glycolipids, iNKT cells respond within hours, reminiscent of innate rather than adaptive fu
Structural Requirements of glycolipid/CD1d Recognition by NKT Cells
Modern electron cryo-microscopy and computer-based, 3D image reconstruction techniques are revolutionizing the way structures of large and complex biomacromolecular machines are studied. These methods provide keys to understanding at the molecu
PARALLEL SOFTWARE FOR FAST, AUTOMATED DETERMINATION OF VIRUS STRUCTURES
This proposal addresses the great need for definitive evidence to test the prevalent dogma that Foxp3+fTregulatory cells are essential for the acceptance of physiologically relevant MHC incompatible organ grafts. MHC-mismatched mouse renal allo
Mechanisms of acceptance of mouse renal allografts
Project Narrative CD46 is a protein that regulates many immune functions in man. CD46 comes in two main forms, and there is reason to believe that the result of CD46 stimulation depends on the relative levels of the two activated forms. CD46 is
CD46 AS A SIGNALING INTERMEDIATE IN N. GONORRHOEAE INFECTION
A critical component of the acute inflammatory response is the rapid mobilization of blood-borne lymphocytes into secondary lymphoid organs. These organs are the staging ground for lymphocyte encounters with antigens and foreign pathogens durin
Inflammatory Control of Lymphocyte Trafficking
Our current understanding of cutaneous innate immunity states that the skin initially protects against infection by establishing physical and chemical barriers to microbes. These include the stratum corneum, antimicrobial peptides, reactive oxy
SKIN MICROBIOME IN EPIDERMAL IMMUNE DEFENSE
This revised proposal (DK081513) focuses on the investigation of serine/threonine phosphorylation of IRS-2 by ERK, mTOR and p70S6K in mediating initial hepatic insulin resistance, Insulin action in the liver plays an important role in maintaini
THE ROLE OF SERINE PHOSPHORYLATION OF IRS-2 IN HEPATIC INSULIN RESISTANCE
This is a translational research study of the role of glucagon-like peptide-1 (GLP-1) in congenital hyperinsulinism (CHI), the most frequent cause of persistent hypoglycemia in children. CHI is a genetic disorder of pancreatic ?µ-cell function
ROLE OF GLP-1 IN CONGENITAL HYPERINSULINISM
The role of innervation for hormone secretion in human islets.   Understanding the biology of the endocrine pancreas, the islets of Langerhans, is crucial for any type of therapy for diabetes mellitus, a devastating disease affecting millions w
THE ROLE OF INNERVATION FOR HORMONE SECRETION IN HUMAN ISLETS
Meta-Analysis Systematic and Design Errors: Alcohol Use and Disease Outcomes  The meta-analysis of relevant epidemiological studies evaluating alcohol consumption and multiple disease outcomes should inform clinicians and public health policy b
Meta-Analysis Systematic and Design Errors: Alcohol Use and Disease Outcomes
This work is directed towards obtaining a better understanding of how the antigen receptor on B lymphocytes contributes to the development of different peripheral B cell populations and to the function of B lymphocytes in humoral immunity. Mole
Studies on peripheral B lymphocyte development
The parent grant focus is on investigating the role of mycobacterial antigens in sarcoidosis pathogenesis. Recent studies from independent laboratories have noted an association with mycobacteria and  sarcoidosis pathogenesis. We found a statis
Role of Mycobacteria in Sarcoidosis Immunopathogenesis
All bacteria possess a single methionine aminopeptidase (MetAP) that is absolutely essential for cell survival. In contrast, eukaryotic cells express two MetAP enzymes and can survive if one of them is eliminated by genetics or inhibition. This
The long term goal of this research project is to understand the role of ehrlichial glycoproteins in protective immunity to Ehrlichia chaffeensis. The proposal aims to further the limited understanding of ehrlichial glycoproteins and their role
Protective Glycopeptide Immunodeterminants of Ehrlichia chaffeensis
T. gondii is an obligate intracellular category B priority pathogen that causes the disease toxoplasmosis and is a model system for other priority B protozoa including Cryptosporidium parvum and Cyclospora caytanensis. Our long-term objective o
Toxoplasma gondii evasion of immune effecter mechanisms
Ribosome inactivating proteins (RIPs) have been used as instruments of biological warfare and terrorism. Ricin is a heterodimeric plant toxin that consists of A and B-chains and the prototype of type II RIPs. Its B- chain is a lectin that enabl
The need for a rapid response to new bioterror threats and emerging infectious diseases is frustrated by the slow pace of drug discovery. We hypothesized in Specific Aims 2 and 3 (see below) that the protein synthetic machinery can be engineere
Directed Evolution of Inhibitors of Anthrax Toxin
The goals of this administrative supplement that will be accomplished within two years are to obtain a complete in vivo temporal gene expression map during Vibrio cholerae infection of an animal model. The proposed experiments are a direct outg
Analysis of gene regulation of vibrio cholerae infection
Innate immune responses of sinonasal epithelial cells to influenza infection in chronic rhinosinusitis with polyps: The purpose of the parent grant is to study innate immune mechanisms that underlie chronic rhinosinusitis with polyps (CRSwNP),
IMMUNE RESPONSES OF THE EPITHELIUM IN CHRONIC RHINOSINUSITIS WITH POLYPS
Transplanted organs such as the skin, lung and small bowel are more immunogenic and more resistant to tolerance induction than the heart and kidney. We reasoned that transplantation of the former organs would more likely result in the concurren
MECHANISTIC STUDIES ON LISTERIA INFECTION AND INHIBITION OF ALLOGRAFT TOLERANCE
We request an administrative supplement to purchase a new piece of equipment that would accelerate the pace of our NIH-funded project to study HIV-1 assembly.   The long-term goal of the parent project is to understand how assembling HIV-1 part
Elucidation of HIV Env acquisition strategies - Administrative Supplement
We request an administrative supplement to purchase a fluorescence microscope which we will use to monitor HIV-1 replication, intracellular aptamer distribution and propagation of infectious HIV-1.  A fluorescence microscope is absolutely essen
Determinates of anti-HIV nucleic acid aptamer potency and resistance - Administrative Supplement
DESCRIPTION (provided by applicant): We propose to develop novel inhibitors of HIV entry that target the highly conserved N-trimer pocket region of HIV gp41. Inhibition of this essential component of HIV's fusion machinery prevents viral entry
Progress in biomedical research and its translation into clinical practice require the integration of data across multiple scales (molecules, cells, organisms), organism types, and fields of research. The need for data integration is especially
Immune system Biological Networks: Case Study Improved Data Integration & Analysis
Our investigations of POH, a hereditary form of heterotopic (extra skeletal) ossification, are an opportunity to understand key factors regulating stem cell fate decisions, specifically those in the musculoskeletal system. Increased understandi
Molecular Genetics of Progressive Osseous Heteroplasia
AbstractThis is a competitive revision application for R01 AR048328 in response to NIH Notice NOT-OD-09-058: 'NIH Announces the Availability of Recovery Act Funds for Competitive Revision Applications'. Osteogenesis Imperfecta (OI) is a genetic
GENE TARGETING STRATEGIES FOR THE DEVELOMENT OF OSTEOGENESIS IMPERFECTA
Osteoporosis is a major health concern among Americans. Osteoporosis is normally characterized by a loss of bone density leading to increased fracture risk. Due to lack of specificity and sensitivity of bone density as a diagnostic measure, foc
Growth of Trabecular Bone Damage Due to Off-axis Loads
Normal functioning of the adult skeleton requires mechanical loading to maintain bone mass.  However the precise mechanism by which bone perceives load, transduces that stimulus into a biochemical response, and ultimately forms new bone is poor
The Role of Lrp5 in BoneResponse to Mechanical Loading
This study uniquely combines technologies from the fields of acoustics and MRI imaging to address a research question that has vexed manual therapists for over a century. The work will deepen the research of the parent grant by allowing further
Z-joint Changes in Low Back Pain Following Adjusting ? Relationship of Cavitation to Z-joint Gapping
Mechanisms of Meditation Mechanisms of Meditation This project will significantly expand the scope of our NCCAM-funded R01 Project entitled ?Mechanisms of Meditation? (R01AT004698-01). It adds an innovative naturalistic observation method to as
The unfolded protein response (UPR) triggers multiple pathways to allow cells to respond to stress conditions that target the endoplasmic reticulum (ER). The ER is a cellular organelle where secretory and membrane proteins are synthesized and m
Stress Induction of Glucose Regulated Protein GRP78/BiP
DESCRIPTION: This application is submitted in response to Notice Number NOT-OD-09-058: NIH Announces the Availability of Recovery Act Funds for Competitive Revision Applications. In this application, additional funds are sought to expand the sc
Tyrosine Protein Kinases and Lymphocyte Activation
Inflammation, Obesity and Risk of Colorectal Adenomas This project will test the central hypothesis that systemic cytokines and adipokines or local biomarkers of inflammation predict risk for colorectal adenomas and low apoptosis within the nor
Inflammation, Obesity and Risk of Colorectal Adenomas
The research award was for two summer students.  This is the second summer of the award.  During this period, the high school student (Jaya Kanduri) who previously worked in the laboratory returned  for a second year. She worked on improving th
Targeting Entry of Retroviral/Lentiviral Vectors
Plasma C-Reactive Protein (CRP) level is a biomarker that predicts future risk of cardiovascular disease.  The specific aims of R01HL088531 are to (1) comprehensively explore patterns of rare variation at CRP by resequencing individuals selecte
Assessing the Impact of Rare Polymorphism at CRP on CRP Levels & Atherosclerosis
Cell magnetophoresis is a cell motion induced by the magnetic field in electrolyte solutions. During the current funding period (ending 01/31/08) we have used Cell Tracking Velocimetry (CTV) to compare effects of binding of various commercial i
MAGNETOPHORETIC CELL SORTING AND ANALYSIS
In our previous application, we designed novel and rational clinical trials, based on our preclinical studies, combining gemcitabine with radiation for the treatment of patients with advanced head and neck cancers and pancreatic cancer that hav
GEMCITABINE-RADIATION FOR ADVANCED PANCREATIC CANCER
The recognition that prostate cancer clusters within families has led many research teams including our own to collect families with multiple cases of prostate cancer for linkage studies. Unfortunately, despite the collection and analysis of a
GENETIC ANALYSIS OF HEREDITARY PROSTATE CANCER FAMILIES
Statistical Methods in Current Cancer Research: ARRA-funded Administrative Supplement. The broad, long-term objectives of this research are the developments of statistical methods for the designs and analysis of clinical and epidemiological can
Statistical Methods in Current Cancer Research - ARRA
Supported by the parent grant “Clinical and Cost-effectiveness of HPV vaccination in the U.S.”, we have developed a series of empirically calibrated models capable of assessing the costs, benefits, and cost-effectiveness of primary preventi
Clinical and Cost-Effectiveness of HPV Vaccination in the US
GENETIC SUSCEPTIBILITY TO CERVICAL CANCER
The MUC1 heterodimeric oncoprotein is aberrantly expressed at high levels in over 90% of human breast cancers. The MUC1 N-terminal subunit (MUC1-N) is a mucin-type glycoprotein that disrupts cell-cell and cell-extracellular matrix interactions.
Oncogenic Signaling by DF3/MUC1 in Human Breast Cancer
The purpose of this application is to request support that was lost from the original budget needed to perform the studies outlined in Specific Aim #3, as well as additional support to augment our proposed studies outline in Specific Aim 3 of o
Use of Beta-Lapachone for Lung Cancer Chemotherapy-ARRA Stimulus Diversity Supplement
Inactivation of the adenomatous polyposis coli (APC) tumor suppressor triggers the development of the vast majority of colorectal carcinomas. Our goal is to dissect the function(s) of APC, and the molecular and cellular consequences of APC inac
APC Tumor Suppressor in Cell Differentiation and Death
TELECONFERENCE GROUP: BREAST CANCER IN AFRICAN AMERICANS The purpose of the supplement request is to increase enrollment in our current randomized clinical trial and to increase our capacity for data analysis.  Our trial investigates the effect
TELECONFERENCE GROUP: BREAST CANCER IN AFRICAN AMERICANS
'The ongoing project (CA197331) as well as the new work proposed in this competitive revision application addresses many important public health concerns including providing drugs to treat several cancers including malignant melanoma. This work
Restoration of Tumor Suppression Activity in Malignant Melanoma
PTEN is a tumor suppressor and the first phosphatase identified to be frequently mutated/deleted somatically in a variety of human cancers. Substantial evidence supports that loss of PTEN promotes the development of human cancer. PTEN normally
Novel Targets that are Deregulated by Loss of PTEN
Most prospective epidemiologic studies have shown that a diet that is low in folate and high in alcohol significantly increases the risk of breast cancer (BC), making the methyl (or one-carbon)-deficient diet one of the few modifiable risk fact
DIETARY METHYL CONTENT, EPIGENETICS AND BREAST CANCER
) leading to this Supplement have provided important insights as to the magnitude and extent of tumor associated eosinophilia. More importantly, these studies have demonstrated that the eosinophilia associated with cancers has growth modulating
Eosinophil Recruitment and Activation in Solid Tumors
Surprisingly, a great deal of ecological evidence shows that prognosis of melanoma is better in areas with high ground level ultraviolet radiation. An individual-level analysis of survival in a Connecticut melanoma cohort also shows that those
SOLAR EXPOSURE AND MELANOMA SURVIVAL: ADMINISTRATIVE SUPPLEMENT
Ovarian cancer causes more deaths each year among North American women than any other gynecologic cancer. The etiology is poorly understood. Although highly penetrant mutations in BRCA1 and BRCA2 are known to significantly increase ovarian canc
Haplotype-Based Genome Screen for Ovarian Cancer Loci
To-labeled cyclic RGDfK tetramers in tumor and other organs, such as kidneys and liver. The purpose of these studies is to maximize tumor uptake and minimize the uptake in other major organs, such as liver and kidneys; thereby improving the tar
TC-Labeled Cyclic RGDfK Tetramers for Breast Cancer Imaging
Women who carry inactivating mutations in the BRCA1 and BRCA2 genes in their germline are at significantly elevate risk of breast and ovarian cancer. Because of the identification of these mutations by clinical genetic testing many mutation car
BRCA2 missense mutations and breast cancer
This 2-year Administrative Supplement application is submitted in response to the American Recovery and Reinvestment Act (ARRA) of 2009, NCI-Activities to Promote Research Collaboration (NCI-APRC). The parent grant of this application is the NC
Breast Cancer Survival:  lifestyle and Genetic Determinants
1)	It will allow us to enhance our ability to detect associations of genetic variants with susceptibility to having mutations in RB1 gene and cause RB disease.   2)	Will allow us to hire additional personnel and train them in the current state-
PARENTAL GENOTYPES AND EXPOSURES IN SPORADIC RETINOBLASTOMA
Ovarian cancer has the highest mortality of all gynecologic cancers, and 70% of women with ovarian cancer die of their disease within 5 years. Survival is high with early stage disease, yet ovarian cancer is not| usually detected earlier than S
OPTICAL IMAGING OF OVARIAN CARCINOGENESIS IN A RAT MENOPAUSE MODEL
Near-infrared fluorescence (NIRF)-based optical imaging of human cancers has several advantages over standard imaging techniques in that it is extremely sensitive, inexpensive, and robust; involves no harmful radiation; and allows real-time vis
NEAR-INFRARED FLUORESCENCE NANOPARTICLES FOR TARGETED O*
PhotoSensitizer Nanoparticle Aptamer Conjugate Therapy (SNACT) is an application of targeted photodynamic therapy (PDT) involving the administration of a photosensitizer (PS) encapsulated in aptamer-bound nanoparticles (NP), followed by light a
Photodestruction of Ovarian Cancer: ErbB3 Targeted Aptamer Nanoparticle Conjugate
We propose to define in greater detail the structural-functional relationship of galectin-3 as its relates to cellular localization, cell growth, apoptosis resistance, cell-cell recognition, angiogenesis, tumor growth and hematogenous spread of
THE ROLE OF TUMOR CELL SURFACE LECTIN IN METASTASES
This NCI-APRC proposal is a new joint effort between Dr. Young Whang, the PI of the parent grant “Regulation of androgen receptor by HER-2 and Ack1 tyrosine kinase”, and Dr. Alex Tropsha, who focuses on optimizing virtual screening approach
Regulation of androgen receptor by HER-2 and Ack1 tyrosine kinases - ARRA
Colorectal cancer (CRC) is one of the most commonly diagnosed cancers and the third leading cause of cancer death among Chinese Americans. Older Chinese Americans have the lowest CRC screening rate in the U.S. Physician recommendation is the st
A Physician-Based Trial to Increase Colorectal Cancer Screening in Chinese
.  Since common epithelial cancers are resistant to most therapeutic treatments, much hope has been placed on prevention of cancer through the use of chemical agents or dietary manipulation.  The widely used nonsteroidal antiinflammatory drugs
The goal of this research is to identify novel susceptibility genes for lung cancer using a systematic genome- wide association-based approach. To achieve this goal, we are applying a two-stage design. This proposal builds upon an extensive res
HIGH DENSITY ASSOCIATION ANALYSIS OF LUNG CANCER
The project is a supplement to the parent grant R01 CA-122704-02. The goals of this Diversity Supplement project are to develop and pilot test cognitive-behavioral coping skills training (CST) protocols tailored for partnered and unpartnered Af
PROSTATE CANCER RECOVERY ENHANCEMENT (PROCARE) FOR AFRICAN AMERICAN MEN
Although individuals with ulcerative colitis face an increased risk of developing colorectal cancer, little attention has been given to the establishment of a chemopreventive regimen for this population. The ability of 5-aminosalicyclic acid (5
CHEMOPREVENTION OF COLITIS-ASSOCIATED NEOPLASIA BY 5-ASA
A transgenic murine model of melanoma was developed by the ectopic expression of metabotropic glutamate receptor 1 (murine GRM1 or mGRM1) in melanocytes. We have expanded these original studies and have now shown that over 65% of human melanoma
Validation of Grm1 as a Therapeutic Target in Melanoma
ARRA The Pirc Rat, a Newly Generated Model for Familial Human Colon Cancer
Human cancers are extremely heterogeneous. Integrative cancer systems biology must develop more comprehensive and incisive methods to interrogate various sources of heterogeneity, and to rationally represent their complex interactions in refine
Gene expression programs of lactic acidosis in human cancers
This project is concerned with the development of a new drug development paradigm that focuses on the use of preclinical studies in animals to derive predictive pharmacokinetic [PK] - pharmacodynamic [PD] models that can aid in the rational sel
DEVELOPMENT OF TARGETED ANTICANCER DRUGS
Carbon nanotubes are graphene sheets of sp2 bonded atoms rolled seamlessly into a tube of 1.5 - 20 nm in diameter. This material has unique properties, including the ability to generate heat when stimulated with infrared light. We have used the
The Epstein Barr virus is an oncogenic herpesvirus that is intimately involved in a number of malignancies in humans. The genetic basis of EBV associated oncogenesis is the concerted action of EBV latency associated genes and varying cellular g
Analysis of Epstein Barr virus type III latency on cellular miRNA gene expression
Tulane Health Sciences Center, 1430 Tulane Avenue
The Aim of this proposal is to implement internet enabled tissue banking and patient annotation software for the collection of esophageal cancer specimens and data at the University of Rochester and the University of Pittsburgh. Our goal is to
BIOMARKERS FOR ESOPHAGEAL CANCER PROGRESSION AND PROGNOSIS
cannibalistic process of autophagy as a survival pathway utilized by solid tumor cells to survive starvation and protect their genome from mutations. We propose to establish the mechanism of autophagy and its consequence to cancer progression
Skin cancer is an important health problem and is a major cause of cancer worldwide.  Skin cancer chemoprevention by diet-derived agents is an important area of study.  In the present proposal we study the ability of green tea  polyphenols to r
The parent grant for this ARRA supplemental funding is National Cancer Institute R01 grant 1R01CA131386-01A1. The major focus of the parent R01 grant was to develop and evaluate the effects of Spanish and English language versions of a personal
Subproject for Institution # 07-004613: Tailored Interactive Multimedia to Reduce Colorectal CA Screening Disparities
The objective of the parent is grant to study the inhibition of lung carcinogenesis by green tea polyphenols and the synergistic action when used in combination with atorvastatin. The inhibitory action and the mechanisms involved will be thorou
Inhibition of Lung Carcinogenesis by Tea Polyphenols and Atorvastatin
The hypotheses of our original application are:  (a) nAChR partial agonists possessing high affinity for nAChRs and varying degrees of agonist and antagonist efficacies and nAChR subtype selectivity will be useful pharmacological tools for stud
Development of Ligands for Nicotinic Receptors
Supplement Topic Area: Accelerating the Science (ACC)  The overarching goals of the proposed and ongoing research in the parent grant are to determine which aspects of sensory and language processing and related neural systems are most dependen
People with sensorineural hearing loss experience difficulties understanding speech in noisy environments and often complain that music sounds distorted or unpleasant. Both of these deficits may be attributed to the functional effects of damage
HEARING LOSS AND THE PERCEPTION OF COMPLEX SOUND
Complex Sound Analysis In Normal And Impaired Listeners ARRA This award is a supplement to a parent Project whose purpose is to characterize the temporal processing deficits in audition that emerge early in the aging process, and to differentia
Complex Sound Analysis In Normal And Impaired Listeners ARRA
The imaging instrumentation requested with the supplemental support was purchased, installed, and calibrated, and is currently being used to acquire data.  Data obtianed with the new instrumentaiton to date have been included in a manuscript th
Chronic middle ear infections including otitis media with effusion and recurrent otitis media are two of the most common reasons that children visit a doctor, receive antibiotics and undergo general anesthesia and surgery. These infections are
MOLECULAR ANALYSIS OF PATHOGENS IN OTITIS MEDIA BY PCR
DESCRIPTION (provided by applicant): The goal of this project is to extend our knowledge of the neural mechanisms that underlie the integration of information from different sensory modalities and their transformation into motor commands to gen
ARRA MULTISENSORY PROCESSING IN THE BEHAVING PREPARATION
Sensory cells, called hair cells are responsible for converting mechanical signals into electrical signals. An series of actin filled microvillae of increasing height sit atop the sensory hair cell being deflected by mechanical stimulation. Thi
A substantial number of military personnel who have served in Iraq (Operation Iraqi Freedom; OIF) and Afghanistan (Operating Enduring Freedom; OEF) report alcohol misuse and symptoms of posttraumatic stress disorder (PTSD) following their retur
Web-Based Behavioral Intervention for Returning Veterans with Risky Alcohol Use
A large body of both human and animal data support the idea that adolescent behaviors can have life-long effects on an individual. This sensitivity may derive, in part, from the dramatic developmental changes in brain function that are taking p
Epigenetics Behind Long-Term and Transgenerational Effects of Adolescent Behavior
Animal studies are insufficient for predicting human liver responses due to significant species-specific differences in liver functions. Therefore, a plethora of in vitro human liver models have been developed over the last three decades to sup
Towards a Miniaturized Human Liver Array for High-Throughput Screening
We suggest statistical techniques to overcome two threats to the external validity of a randomized controlled trial and apply our techniques to the example of the Women's Health Initiative Estrogen + Progestin study. New methods to detect and c
NATURAL EXPERIMENTS AND RCT GENERALIZABILITY: THE WOMEN???S HEALTH INITIATIVE
The central focus of this proposal explores how to fill a technological gap - the detection of specific A¿ oligomers in living subjects. The development of new techniques for measuring specific A¿ oligomers in living individuals will enable u
Perhaps the most urgent scientific challenge for the 21st century is to develop interventions to slow the process of cognitive aging so that at the end of life, most older adults are in control of their mental faculties and they and their famil
IMPACT OF EXERCISE AND ENGAGEMENT ON COGNITION IN OLDER ADULTS
This application addresses broad Challenge Area (15) Translational Science and specific Challenge Topic, 15-AI-102*: Develop diagnostics and drugs for multiple or extensively drug-resistant tuberculosis (MDR/XDR TB). Mycobacterium tuberculosis
Development of adamantyl ureas against MDR/XDR M.tb
This application addresses broad Challenge Area (15) Translational Science, and specific Challenge Topic, 15-AI-106: Translational research focused on high priority pathogens and basic research focused on resistance mechanisms. Infections by Ch
RECOMBINATION AND GENETICS IN CHLAMYDIA SPP.
The goal of this project is to develop a way to observe whether or not new therapies are effective in correcting the disease process in muscles of boys with Duchenne muscular dystrophy (DMD) without the need to take muscle biopsies. We will ext
MR MONITORING OF PTC124 TREATMENT IN DMD
The systemic vasculitides are a group of diseases characterized by severe inflammation of blood vessels leading to arterial stenosis or occlusion, and organ damage or death if untreated. Two related vasculitides, Wegener's granulomatosis (WG) a
Identification and Validation of Biomarkers for Vasculitis
Genotyping the NPF Biobank for Psoriasis Susceptibility Genes This application addresses broad Challenge Area (08) Genomics and Specific Challenge Area: 08-AR-101 Genotyping of Existing Cohorts in Rheumatic, Skin, and Musculoskeletal Diseases.
GENOTYPING THE NPF BIOBANK FOR PSORIASIS SUSCEPTIBILITY GENES
This current application addresses Regenerative Medicine (11) as the broad challenge area. Specifically, this application seeks further understanding of molecular pathways that control expansion and differentiation of periosteal mesenchymal ste
HEDGEHOG PATHWAY IN PERIOSTEUM-MEDIATED REPAIR AND REGENERATION
This application addresses broad Challenge Area (03) Biomarker Discovery and Validation and specific Challenge Topic, 03-AR-103: Biomarkers: Bench to Bedside for Autoimmune and Inflammatory Skin and Rheumatic Diseases. Some patients with humora
Functionally Linking Autoimmune Subjects to Novel Therapies Using Biomarkers
The awarded project is aimed at performing a genome-wide association scan on 600 individuals with systemic lupus erythematosus of Hispanic ancestry and 200 healthy controls. The aim is to search in particular for risk variation of Amerindian or
Identification of Susceptibility Genes for SLE of Amerindian Origin in Hispanics
This application addresses broad Challenge Area (06) Enabling Technologies and specific Challenge Topic: 06-AR-103, Systems Biology for Skin and Rheumatic Diseases. Psoriasis (PS) is a complex inflammatory skin disease where genetic risk factor
This application addresses broad Challenge Area (05) Comparative Effectiveness Research and specific Challenge Topic, 05-AR-102: Comparative Effectiveness (CE) of Treatments for Chronic Childhood Arthritis and Musculoskeletal (MSK) and Skin Dis
Severity Scale and Quality of Life Instrument for Infantile Hemangiomas
In adult mammals, muscle stem cells (MuSCs) proliferate less, there is less new muscle produced, and there is more fibrosis, than in young mammals. These effects are at least partly due to soluble molecules that regulate MuSCs and their progeny
Remote-control mouse-implantable micropumps for establishment of regenerativecap
A full 1 in 5 children in the US has a developmental disability, and the prevalence rate for autism spectrum disorders (ASD) is especially high (1 in 150 children). As many as 20% of US families are raising children with developmental disabilit
Conventional Vs Mindfulness Intervention in Parents of Children with Disabilities
This application addresses broad challenge area 'Stem cells' and specific area: 'Understanding the Heterogeneity of Cancer and its Environment' (14-CA-102). Tumor stroma interactions are widely recognized to be crucial modifiers of the biology
Identification of functional tumor-stromal interactions in the bone marrow
DESCRIPTION (provided by applicant): This application addresses broad Challenge Area (15) Translational Science and specific Challenge Topic, 15- OD(ORDR)-101: Pilot projects for prevention, early detection and treatment of rare diseases. Curre
CHARACTERIZING THE MOLECULAR SIGNATURES OF RARE INHERITED COLON CANCER SYNDROMES.
Role of Advanced Screening Technologies for Early Detection of Breast Cancer Project Summary/Abstract This application addresses broad Challenge Area (05): Comparative Effectiveness Research and specific Challenge Topic, 05-CA-105 CISNET (The C
Role of Advanced Screening Techologies in Early Detection of Breast Cancer
This application addresses broad Challenge Area (05) Comparative Effectiveness Research and specific Topic 05-CA-104* Comparative Effectiveness Research on Cancer Treatment. Effectiveness of prostate cancer treatment has been previously evaluat
Effectiveness of Early Stage Prostate Cancer Treatment
Tumors vary greatly in the course of disease and in how they respond to specific therapies. Molecular diagnostic methods that can be used to classify tumors and predict their behavior have enormous potential to both increase the effectiveness o
A NOVEL MOLECULAR DIAGNOSTIC APPROACH TO CLASSIFY LUNG CANCERS AND PREDICT RESPON
The researcher will develop analytical imaging capabilities with complementary nanoparticle probes to measure the viscoelastic properties of cells and tissues in a noninvasive manner. These capabilities will be applied toward understanding biom
Investigating Tumor Growth Dynamics Using Multimodal Contrast Agents and Optical
The specific aims of this project are to build on this previous work and momentum to: 1. Design patient-reported outcomes (PRO) system functionality and processes for breast cancer survivors, and develop high-priority system features, including
WEB-BASED PATIENTREPORTED OUTCOMES (PRO) SYSTEM FOR BREAST CANCER SURVIVORS
This application addresses broad Challenge Area (15) Translational Science and specific Challenge Topic, 15-CA-112: Cancer Cell Energy Metabolism and Cancer Causation The molecular events that covert normal cells into tumor cells alter cellular
Role of Tumor and Stromal Cell Metabolism in Stress Adaptation and Progression
The proposal 'Amphetamine acts as a Molecular Stent in the Dopamine Transporter' addresses the specific problem of amphetamine addiction, and introduces drug development strategies for detoxification of drug abusers. The central hypothesis rest
Amphetamine acts as a Molecular Stent in the Dopamine Transporter
Phenotypic Markers for Smoking Cessation: Impulsive Choice and Impulsive Action This application addresses broad Challenge Area (01): Behavior, Behavioral Change, and Prevention and specific high-priority Challenge Topic 01-AA-101 Identifying P
Phenotypic Markers for Smoking Cessation: Implusive Choice and Impulsive Action
addresses the broad Challenge Area (15) Translational Science and specific Challenge Topic, 15-DA-112: New Models and Measures in Preclinical Chronic Pain Research. Our long-term goal is to uncover mechanisms for suppressing pathological pain
An Animal Model of Therapeutic Self-Medication for Neuropathic Pain
Medication development for substance dependence. abstract:This application addresses broad NIH Challenge Area 04: Clinical Research and specific Challenge Topic 04-DA-101: Evaluation of novel, rationalized poly-pharmacotherapeutic treatment str
Modafinil and Escitalopram for Cocaine Addiction
The Primary Specific Aim of this proposal is to compare, using drug abstinence as the measure, the effectiveness of an episodic care model (TAU) and a continuous care model  (LTRM) of substance abuse treatment among drug-dependent adults enteri
Comparing Acute and Continuous Drug Abuse Treatment:  A Randomized Clinical Trial
This research proposes an alternative approach for characterizing neuron intrinsic active properties, and indentifying a neuron's complete set membrane currents, individual-neuron-by-individual neuron.  The key idea is that measuring the respon
Using Perturbation to Characterize, and Build Models of Individual Neurons
This proposal meets the requirements of two major Challenge Areas within Clinical Research, 'Prevention of otitis media' (04-DC101), and 'Develop novel methods and address key questions in mucosal immunology' (04-AI-101). Otitis media caused by
This application addresses broad Challenge Area 11, entitled Regenerative Medicine. The specific Challenge Topic is 11-DC-101, Hair Cell Regeneration and Maintenance. Deafness and lesser degrees of hearing impairment have an enormous impact on
Gene-Expression Patterns During Hair-Cell Regeneration
This application addresses broad Challenge Area (03) Biomarker Discovery and Validation, and specific Challenge Topic, 03-DE-101: Development, Refinement, or Validation of Biomarkers Relevant to Oral or Craniofacial Disorders. The goal of this
ARRA: Saliva and Serum Inflammatory Biomarkers in Periodontitis: A Prospective Study in Older Women
There has been a remarkable growth in translational research organized around the screening, brief intervention and referral services (SBIRT) concept, with numerous clinical trials conducted, new screening tests developed, and implementation pr
COMPARATIVE EFFECTIVENESS AND FEASIBILITY OF SBIRT IN A GENERAL DENTAL CLINIC
This application addresses the broad Challenge Area (13) Smart Biomaterials - Theranostics and the specific Challenge Topic, 13-DE-102: Dental Resin Composites and Caries. With a majority of the more than 100,000 million dental restorative trea
Improved Resin Bonded Dental Restoratives Based on Nanogel-modified Adhesives
This application addresses broad Challenge Area (06) Enabling Technologies, and specific Challenge Topic 06-DE-102 Structural and Molecular Atlases of Craniofacial Development. We propose to construct a developmental atlas for the craniofacial
A Developmental Craniofacial Atlas for the Zebrafish
This project will address the lack of randomized controlled studies and comparative effectiveness research in bariatric surgery by utilizing a three arm randomized trial to compare medical and surgical treatments for Type 2 diabetes.  Understan
A Randomized Trial to Compare Surgical and Medical Treatments for Type 2 Diabetes
This application addresses broad Challenge Area, 04-DK-103: Develop Novel Approaches to Understand and Treat Functional Disorders. We plan to determine the role of diet and how genotype contributes to the development of functional GI and motili
IRRITABLE BOWEL SYNDROME-DIARRHEA: THE ROLE OF GLUTEN INTOLERANCE AND HLA-DQ2
Chronic kidney diseases take one of the highest tolls on human health. Steroid-resistant nephrotic syndrome (SRNS) is a rare disease that constitutes the second most frequent cause of ESKD in children and young adults. No curative treatment is
Exon Capture and Large-Scale Sequencing for Disease-Cause Identification, Early Detection and Drug Discovery in Nephrotic Syndrome
This project, 'Engineered in vivo nuclear fusion: application to regenerative medicine,' focuses on the development of a new cell-based strategy for regenerative medicine and gene therapy which depends upon the ability to genetically engineer h
Engineered in vivo nuclear fusion: application to regenerative medicine
This application addresses broad Challenge Area (03) Biomarker Discovery and Validation and specific Challenge Topic 03-DK-101: 'Discovery of biomarkers for disease risk, progression or response to therapy in diseases of interest to NINDK'. Los
Drug-induced liver injury (DILI) is the major adverse drug event that leads to regulatory actions on drugs, including failure to approve, restricted indications, and withdrawal from the marketplace.  The most problematic form of DILI is ?idiosy
Revolutionizing Preclinical Detection of Risk Factors For Idiosyncratic Drug-Induced Liver Injury
This application addresses broad Challenge Area (15) Translational Science and specific Challenge Topic 15-DK-106: Translating basic hematology concepts. Haploinsufficiency of ribosomal protein (rp) genes underlies the inherited marrow failure
Model systems for hematologic disorders caused by ribosomal protein deficiency
The application addresses the broad Challenge Area (15) Translational Science and Specific Challenge Topic, 15-ES-101; Effects of environmental exposures on phenotypic outcomes using non-human models. This application will apply non-human model
ARRA: Role of Parkin in Regulating Manganese Toxicity
Novel Approaches to Evaluate Carbon Nanotube Health Impacts.  Our work will provide a broad understanding of how inhaled ultrafine or nanosized particles in the form of single-walled carbon nanotubes (SWCNTs) produce effects through physical or
Novel Approaches to Evaluate Carbon Nanotube Health Impacts
Discovery of Small Molecule MBT Domain Antagonists-ARRA  DISCOVERY OF SMALL MOLECULE MBT DOMAIN ANTAGONISTS  Abstract: Multicellular organisms have evolved elaborate mechanisms to enable the differential and cell-type specific expression of gen
Discovery of Small Molecule MBT Domain Antagonists-ARRA
Most existing technologies can only measure the properties of a population of cells and not the properties of individual cells. C. elegans is unique among model organisms in that the complete cell lineage is known, enabling one to identify each
High-throughput technology for automated single cell expression analysis for C. e
This application addresses Challenge Area #15:Translational Science and Specific Challenge Topic, 15-HD-102: Pelvic Pain. We propose to characterize the pain with menses and noncyclic pelvic pain in women with uterine leiomyomas at baseline and
Comparing focused ultrasound and uterine artery embolization for uterine fibroids
This application addresses broad Challenge Area (12): Science, Technology, Engineering, and Mathematics Education (STEM), and specific Challenge Topic (12-OD-101*): Efficacy of Educational Approaches toward Promoting STEM Competencies. The prop
(ARRA) Efficacy of the core knowledge approach to math and science preschool instruction
before final disposal. This prototype data dissemination system will be tested for (1) system functionality (i.e., does it remove the usual barriers to data access?); (2) storage and computing security (i.e., does it keep the data secure?); an
EXPLORING NEW METHODS FOR PROTECTING AND DISTRIBUTING CONFIDENTIAL RESEARCH DATA
During this past quarter, several additional research sessions using the Light-Weight Robot III (LWRIII) robot were performed.  A 3D target placement system was created and utilized in sessions to allow for statistical analysis of performance i
CORTICAL CONTROL OF AN ASSISTIVE ROBOTIC ARM
This application addresses broad Challenge Area (06) Enabling Technologies and specific Challenge Topic 06-HG-103: Methods to sequence highly variable, repeat-rich regions of complex genomes. A remarkable 45% of our genome consists of repetitiv
APPLYING TRANSPOSON MAPPING TECHNOLOGY TO DESCRIBE HUMAN GENETIC DIVERSITY
This application is intended for the (06) 'Enabling Technologies' challenge area & (06- HG-102*) 'Technologies for obtaining genomic, proteomic, & metabolomic data from individual viable cells in complex tissue' challenge topic. The specialized
Quantification of gene expression in targeted rare cells in vivo
This application addresses broad Challenge Area (02) Bioethics and specific Challenge Topic, 02-HG-101: Informed consent and data access policies. The ethical, legal, and social issues (ELSI) underlying the development and implementation of sta
INFORMED CONSENT AND DATA ACCESS ISSUES IN STATE-BASED BIOBANKS
The recruitment of American Indians and Alaska Natives (AI/AN) to participate in research is complicated by a long and troubled history between researchers and Native populations of the United States regarding the collection of Native American
Engaging Tribal Participation in Research through Priority Setting and Regulation
Community Voices on Health Disparities and Translational Genomics Research Challenge Area and Specific Challenge Topic: The Challenge Area this research addresses is 02: Bioethics and the Specific Challenge Topic is 02- OD9OSP-102* Ethical Issu
Community Voices on Health Disparities and Translational
DESCRIPTION (provided by applicant): This application addresses broad Challenge Area (06) Enabling Technologies, and Specific High-Priority Topic Area 06-OD(OBSSR)-101* 'Using new technologies to improve or measure adherence'. The chronic disea
Modifying Physical Activity and Sedentary Behavior via Mobile Phone Technology
This application addresses the broad Challenge Area (06) Enabling Technologies, and specific Challenge Topic, 06-OD(OBSSR)-101*: Using new technologies to improve or measure adherence. We propose the development and testing of a novel technolog
USING A NOVEL TECHNOLOGY TO IMPROVE ADHERENCE: SCHOOL-BASED ASTHMA TREATMENT
This application addresses broad Challenge Area (04): Clinical Research, and specific Challenge Topic, 04- HL-104: Perform secondary analyses of existing data to answer important clinical and preventive medicine research questions. Atrial fibri
EPIDEMIOLOGIC STUDY OF RISK FACTORS AND BIOMARKERS OF ATRIAL FIBRILLATION
African-Americans have an approximately 30% to 60% increased incidence of venous thromboembolism (VTE) for unknown reasons.  The main limitation to studying this disparity is the paucity of African-Americans in most large-scale epidemiological
Reasons for Racial Disparities in Various Thromboembolism
P311 is an 8 kDa intracellular protein highly conserved across species. P311 does not belong to any established protein family; neither has signature motifs that could suggest function. In mouse and human P311 is produced in the brain, in vascu
MONOCYTE P311 EXPRESSION LEVEL AS PREDICTOR OF HYPERTENSION IN MICE
This application addresses broad Challenge Area (04) Clinical Research and specific Challenge Topic, 04-HL- 113: Cost-Effective Trials of CVD Prevention in Persons with Low Short-Term Risk. Lipid-lowering therapy with HMG-CoA reductase inhibito
Generic Risk Stratification to Identify Individuals for Early Statin Therapy
We plan to conduct a series of 3 studies in which the results of the first 2 will inform the design of the third.  In study 1, we will evaluate alternative methods and protocols for measureing medication adherence and using the results to impro
TeleHealth & Remote Measurement Technologies to Improve Med Adherence in HTN
This grant addresses Challenge Area (03) Biomarker Discovery and Validation and specific Challenge Topic, 03-HL-101 and is entitled, ?Biomarkers of Sudden Death and Progressive Heart Failure?. More than 5 million people in the United States alo
BIOMARKERS OF SUDDEN  DEATH AND  PROGRESSIVE HEART FAILURE
DESCRIPTION (provided by investigator): This application addresses broad Challenge Area (08) Genomics and specific Challenge Topic, 08-HL-104: Assess genetic variation in African Americans and determine its effect on disease. Genome-wide associ
Genetics of Hypertension Risk Factors and Sequela in African Americans
This application addresses broad Challenge Area (14) Stem Cells and specific Challenge Topic, 15-HL-102: Develop new therapeutic strategies for heart, lung, and blood diseases based on microRNA technology. Congenital heart malformations are the
LET-7 MIRNA CONTROL OF HEART DEVELOPMENT
Develop technologies for assessment of aortic aneurysms prone to rupture or dissection. Thoracic and abdominal aortic aneurysms (TAA and AAA) are life threatening conditions that comprise the thirteenth leading cause of death in the United Stat
Microfibril Fragments:  Biomarkers of Aortic Disease
Hybrid Revascularization vs Percutaneous Coronary Intervention: A Planning Grant  This application addresses broad Challenge Area (04) Clinical Research and specific Challenge Topic, 04-HL-115: Treatment of stenosed coronary arteries with hybri
Hybrid Revascularization vs PCI: A Planning Grant
Current FDA post-marketing drug safety monitoring relies principally on passive surveillance via MedWatch reports to the Adverse Event Report System. By contrast, active surveillance using population-based healthcare utilization databases could
for Drug Safety Monitoring Using Healthcare Databases
This application addresses broad Challenge Area (10) Information Technology for Processing Healthcare Data, 10-LM-102: Advanced decision support for complex clinical decisions. The lack of prescribing information & meaningful dosing guidance pl
DECISION SUPPORT SYSTEM TO GUIDE PEDIATRIC PHARMACOTHERAPY
Our proposal addresses the following challenge area: 06-LM-101* Intelligent Search Tool for Answering Clinical Questions. Develop new computational approaches to information retrieval that would allow a clinician or clinical researcher to pose
Multi-source clinical Question Answering system
Artificial Intelligence (AI) and advanced computational techniques, applied to complex, multidimensional, streaming, clinical data (historic, physiologic, laboratory, imaging, etc) from disparate health care digital data sources, can be used to
Advanced Computational Framework for Decision Support in Critically Ill Children
The research focuses on the critical need to develop patient level interventions to increase the representation of African Americans in cancer trials.  The prurpose is to design and assexss the impact of culturally appropriate educational video
Today's Truth - Research Brings Hope: Ethical Issues in Health Disparities and Access to Participation in Research.
HOPE Accounts for Women - ARRA This award addresses broad Challenge Area (09): Health Disparities and specific Challenge Topic 09-MD-101: Creating Transformational Approaches to Address Rural Health Disparities.  HOPE Accounts for Women is an i
The purpose of this clinical trial is to study the effectiveness of a weight management intervention for pediatric obesity adapted for a low income, racially and ethnically diverse disparity population on child BMI in a sample of 140 obese chil
Adapting Pediatric Obesity Treatment Delivery to Address Health Disparities
This Spanish-Language computerized counseling intervention will deliver evidence-based treatment support to a highly vulnerable Latino population. We will evaluate effectiveness on medication and clinic visit adherence and biological outcomes.
A Spanish-Language Intervention to Enhance Routine HIV Patient Care
The central aim of the study, is to differentiate the alterations in cognitive and affective circuitry in pediatric bipolar disorder (PBD) and attention deficit hyperactivity disorder (ADHD) relative to typically developing operations. PBD and
Brain Mechanisms in Pediatric Bipolar Disorger and attention deficit hyperactivity disorder
We seek support to recruit an extremely promising young radiochemist to join a substantial group of neuroscience investigators. Our candidate would be a new faculty member, does not have a current tenure-track appointment, has outstanding resea
Radiochemist for Drug Abuse PET Probe Development
The Biochemistry Program at Dartmouth Medical School performs a critical role in the biomedical enterprise through training the next generation of physicians and scientists, advancing knowledge across multiple disciplines, and developing facult
Developing Faculty Leaders in the Biomedical Sciences
This proposal from the University of Connecticut seeks funding to support re-opening a previous faculty search in the broad area of NMR-based structural biology that was suspended to economic conditions. The faculty recruit will be expected to
NEW FACULTY RECRUITMENT IN NMR STRUCTURAL BIOLOGY
The Department of Genetics at North Carolina State University was founded in 1958 and has established a long and esteemed record of contributions to quantitative genetics using model organisms. The Department of Genetics is housed in the four-s
New Faculty Recruitment for Systems Genetics Research Core Center
This P30 application seeks to provide resources to recruit Dr. Eric Schmidt to lead the Molecular Physiology and Imaging Core (MPIC) in the Division of Pulmonary Sciences and Critical Care Medicine. The Division is based at the University of CO
Molecular Physiology Core Applied to Acute Lung Injury
The objective of this proposal is to develop a Core Center within the Center for Excellence in Pulmonary Biology to conduct multidisciplinary, biomedical research to elucidate the molecular mechanisms that direct alveolar development. This Core
Postnatal Lung Development: Mechanisms of Molecular and Vascular Development
Over the past two decades the importance of glial cells in normal brain development has become increasingly appreciated. In addition to their well recognized role in normal brain function, dysfunction of glial cells are now recognized to be of
CENTER FOR GLIAL BIOLOGY IN MEDICINE RESEARCH RECRUITMENT CORE CENTER
The United States Department of Agriculture (USDA) allocated $2,872,047 to the Pennsylvania Department of Education (PDE).  The money is required to be distributed to schools that participate in the National School Lunch Program (NSLP) through
CHILD NUTRITION RECOVERY ACT-NSLP EQUIPMENT
The PR Department of Education received funds through the American Recovery and Reinvestment Act of 2009 (ARRA) to assist in the purchase of equipment for School Food Authorities (SFAs) participating in the National School Lunch Program (NSLP)
We appreciate the opportunity to refocus this application to achieve a single important aim related to our understanding of young adults' use of male liquor (ML), other alcoholic beverages, and marijuana (MJ), all of which confer high risks for
ARRA: Malt Liquor and Marijuana; Factors in Their Concurrent Versus Separate Use
Project NarrativeThe proposed research in this first time RO1 has important implications for improving the health of functionally impaired older Americans and their informal caregivers in ethnically diverse and vulnerable communities. By identi
Caregiving Dyads in Vulnerable Communities
ARRA - TRANS-NIH RECOVERY ACT RESEARCH SUPPORT -Chronic inflammation is a critical factor in the pathogenesis of Parkinson’s disease (PD). Neuronal and glial prostaglandins mediate proinflammatory responses, but there is a profound gap in our
Inflammation and the Ubiquitin/Proteasome Pathway in Neurodegeneration
Patients with Werner syndrome exhibit many of the features of premature aging including atherosclerosis and an increase in specific cancers. The gene mutated in Werner syndome, WRN, is a member of the RecQ family of DNA helicases and encodes bo
THE WERNER SYNDROME PROTEIN IN DNA REPLICATION, MUTAGENESIS AND GENOMIC STABILITY
Two billion people - one third of the world's population - live at risk for malaria and some 1 billion people carry the parasite. Clinical malaria hits 300 million to 500 million people each year, killing 2 million to 3 million - most of them c
Imaging preerythrocytic Plasmodium stages in naive and immune individuals
Recently a novel intracellular virus recognition pathway was described that appears to be crticial for host innate immune responses to a viral infection.  We aim to further dissect this pathway and explore its ramifications.  Given the critical
The worldwide AIDS epidemic is most devastating in developing countries where more than 40 million people are infected.  In addition, to the risk of HIV-1, the majority of inhabitants in developing countries are also infected with immune suppre
The Effect of Helminth Infection on HIV-1 Vaccines
The liver has a capacity to sequester activated CD8+ T cells from the circulating pool, due in part to the expression of adhesion molecules on the hepatic sinusoidal endothelium. However, both the detailed mechanisms responsible for this seques
The overall goal of the proposal is to determine the mechanisms responsible for the super agonist activity of cytokine/anti-cytokine mAb complexes. The biological activity of many administered cytokines can be greatly boosted by first binding t
Modulation of T Cell Responses with Cytokines
The paradigm that inflammation stimulates adaptive immunity is well established. Paradoxically, mounting evidence reveals that some forms of inflammation create local suppression, particularly in tissues subjected to chronic inflammation caused
T CELL REGULATION BY IDO-COMPETENT PLASMACYTOID DENDRITIC CELLS
The overall objective of this proposed project is to understand the mechanisms responsible for enhanced susceptibility to Streptococcus pneumoniae that follows influenza infection. Despite being a recognized clinical problem that causes many, i
Effect of Influenza Infection on Alveolar Macrophage Function
Repertoire of antigen receptors (TCRs) on T cells is shaped by interactions between TCRs and MHC molecules bound with peptides of self and non-self origin. In thymus, these interactions promote differentiation of T cells with TCRs with low/inte
In an effort to develop new targets for antibacterial drug discovery, we recently discovered that Gram positive bacteria use a unique and essential pathway to synthesize their membrane phospholipids mediated by two gene products, PlsX and PlsY.
TARGETING THE PLSX/Y PATHWAY FOR NOVEL ANTIMICROBIALS
Bacterial microcompartments are large subcellular structures composed of metabolic enzymes encapsulated within a protein shell built from multiple subunits. They are widespread among bacteria, functionally diverse, play vital metabolic roles, a
Dissecting the Structure and Function of the PDU Microcompartment in Salmonella
The emergence of serum antibody responses only after early cellular immune responses have suppressed HIV replication has led to doubts regarding the importance of humoral immunity in controlling HIV infections. Nonetheless, rare, broadly cross-
B-cell Tolerance and Humoral Immunity to HIV-1
The goal of this study is to better understand the body's immune response to worms that invade human tissues. Results may lead to better approaches for developing vaccines against worms and to new concepts for how to treat autoimmune and allerg
Role of basophils and IgE in the immune response to Litomosoides
Skeletal age is an important clinical tool in the management of children with growth disorders, genetic syndromes and those receiving hormonal, orthopedic or orthodontic treatments.  It is also a useful epidemiological variable that helps to ac
Updating Skeletal Maturity Methods for U.S. Children
Humanized transgenic mice reproduce the disease evolution of severe RA  Rheumatoid arthritis (RA) is a common autoimmune disease found in close to 1% of the general population. Although some patients may have only moderate disease symptoms for
HUMANIZED TRANSGENIC MICE REPRODUCE THE DISEASEEVOLUTION IN SEVERE RA
Osteoarthritis (OA), the most common form of arthritis, is a slowly progressive degenerative disease of joint cartilage that afflicts 40 million Americans. Existing pharmacologic therapies (acetaminophen, non- steroidal anti-inflammatories (NSA
A Multisite RCT Investigating the Efficacy of Massage in Patients with Osteoarthritis
UMDNJ Institute of Complementary & Alternative Medicine
The transformation of the prostate epithelium, and progression to invasive carcinoma, involves de-regulation of the differentiation process, increased proliferation and decrease in apoptosis. A family of transcriptional regulators, known to reg
Inhibitor of Differentiation Gene Expression and Function in Prostate Cells
The long-term objective of our laboratory is to identify novel molecular targets for cancer.  Kras is one of the most frequently mutated oncogenes in human cancer.  Kras mutations are prevalent in lung, pancreas and colon carcinomas. We previou
Identification of Novel Kras Effector Pathways in Lung Cancer
(Also known as serine/threonine kinase 11, STK11) tumor suppressor is mutationally inactivated in Peutz-Jeghers syndrome (PJS), an autosomal dominant disorder characterized by gastrointestinal polyps, mucocutaneous pigmentation, and a markedly
THE ROLE OF LKB1 IN THE MAINTENANCE OF GENOMIC STABILITY.
The lymphatic vasculature plays a critical role in the pathogenesis of many diseases including inflammatory disorders, lymphedema, tumor progression, and metastasis. More recently, the important role of lymphatic vessels in disease states such
MOLECULAR TARGETING OF LYMPHATIC ENDOTHELIAL RECEPTORS FOR LIGAND-DIRECTED IMAGIN
In this proposal, we seek to develop a set of new tools to assess and enhance the efficacy of anti-cancer therapies that have immediate clinical relevance.  In particular, we have developed and embedded methods for real-time quantitative parame
Ultrasonic assessment of therapeutic  response
The prognosis of patients with malignant gliomas remains dismal. To treat patients with this deadly disease more effectively, we must identify the common aberrations in the signaling pathways that are responsible for the invasive and drug-resis
MERLIN SIGNAL IN GLIOMA: THERAPEUTIC AGENTS AND TARGETS
For three decades, alterations of protein-coding oncogenes and tumor suppressors genes have been considered as the causes of tumorigenesis. Recent advances proved without doubts that cancer is a complex genetic disease involving structural and
MICRORNAS AND OTHER NON-CODING RNAS IN COLORECTAL METASTASIS
class). Our preliminary data indicate that DASL can successfully profile and recover the 2-class structure from FFPE primary melanomas in the Nurses Health Study 1. The Channing Laboratory at Brigham and Women's Hospital is home to large cohor
Molecular Signatures of Melanoma Histology and Progression:  A population based approach
Role of cellular senescence in mammary cancer prevention by rexinoids   The main goal of this grant proposal is to determine the role of cellular senescence (CS) as a potential intermediate (surrogate) endpoint in mammary cancer
Role of Cellular Senescience in Mammory Cancer by Rexinoids
Epstein-Barr virus (EBV) infection is an important cause of lymphomas in AIDS patients, especially in central nervous system lymphoma (CNS lymphoma). EBV transforms human primary B cells in vitro, the process of which is believed to resemble EB
Modulation of Apoptosis by IRF-4 in EBV transformation
CANCER PREVENTION INSTITUTE OF CALIFORNIA
Associations of socioeconomic status (SES) with breast cancer risk and survival are well described. The risk of breast cancer is lower in women of lower SES, while survival after breast cancer in these groups is poorer for certain racial/ethnic
Impact of Contextual Factors on Disparities in Breast Cancer Risk and Survival
Silencing RNA (siRNA) is of considerable current interest in biological research because it can elicit potent, target specific knockdown of any mRNA, creating a useful and proven genetic surrogate tool. However, a key problem for effective appl
TARGETED AND TRACEABLE DELIVERY OF SIRNA WITH NANOPARTICLE-AMPHIPOL
DESCRIPTION (provided by applicant): Breast cancer is responsible for the second overall cause of cancer-related deaths among women. Despite this profound health risk, Immunotherapy for breast cancer has not been adequately developed as an inte
AUTOIMMUNE INDUCED BREAST FAILURE AS A STRATEGY FOR BREAST CANCER VACCINATION
Improving Care Continuity in Drug Abuse Treatment Drug users generally benefit from continuing treatment in an outpatient program following their stay in a residential treatment setting. This project will set up linkages between residential and
IMPROVING CARE CONTINUITY IN DRUG ABUSE TREATMENT
Organismal and Genetic Networks in Drug Reward and Reinforcement - ARRA  The goal of this project is to examine genetic pathways involved in addiction by using a mouse model of initial sensitivity to cocaine. The project involves behavioral, ph
Organismal and Genetic Networks in Drug Reward and Reinforcement - ARRA
Schizophrenia is a major debilitating brain disorder that affects 1% of the world's population. There is a 90% prevalence rate of comorbid nicotine addiction in schizophrenic patients leading to high morbidity and mortality rate in this vulnera
Varenicline and Smoking Cessation in Schizophrenia
Innovative strategies for tobacco cessation must be considered. Currently, there are 44 million smokers in the US and 1.2 billion smokers world-wide. Although 22 million smokers try to quit smoking each year, only 3-5% are successful in becomi
Innovative Interventions for Smoking Cessation
The 'Preventing Drug Abuse & HIV/AIDS in Delinquent Youths: An Integrated Intervention' study is a 2-year randomized trial of a family-centered preventive intervention for adolescent boys involved in the juvenile justice system who are at high
Preventing Drug Abuse & HIV/AIDS in Delinquent Youths: An Integrated Intervention
Neurological symptoms with methamphetamine (METH) toxicity of the nigrostriatal system, both in rodent models and in drug abusers, are associated with neuroinflammation, a fundamental reaction to brain injury characterized by activated microgli
NEUROINFLAMMATION AND GLIAL ROS IN METHAMPHETAMINE NEUROTOXICITY
Given the severe and often life-long consequences linked to drug abuse, criminal involvement, and risky sexual behavior in childhood and adolescence, early intervention is considered by many to be crucial to halt the progression of these devast
LONG-TERM OUTCOMES AND ECONOMIC IMPACT OF THE DETENTION TO COMMUNITY MODEL.
Cannabis use disorders are a significant public health concern that disproportionately affect youth. Although promising psychosocial interventions are being developed, most youth do not benefit from these interventions alone. In light of the cl
BIOBEHAVIORAL EFFECTS OF TOPIRAMATE ON CANNABIS-RELATED OUTCOMES IN ADOLESCENTS
as defined in the award description.  PI has left the University.  Final report will be submitted next qtr
The role of cocaine-induced changes in OMPFC neurophysiology in cocaine addiction
The goal of this project is to define the function of the basic helix-loop-helix transcription factor Hand2 during mammalian lower jaw development. Our hypothesis is that Hand2 contributes to the development of most lower jaw structures by esta
Hand2 Function and Regulation During Craniofacial Development
The first specific aim is designed to investigate whether mina biogenesis is essential for liver regeneration. This will be done by specific knockdown of critical components of Dicer in mina processing and Ago2 in the RNA Induced Silencing Comp
microRNA Uncoupling of Protein and Transcript Expression in Liver Regeneration
The studies will elucidate the key role of Toll-like receptor 4 and kidney dendritic cells in the induction of the inflammatory phenotype of the kidney during acute injury. These results will be relevant because they are expected to lead to cli
EPITHELIA/DENDRITIC CELL CROSS TALK IN ACUTE KIDNEY INJURY
Our goal is to understand molecular mechanisms involved in the diurnal regulation of plasma lipids. We observed that plasma triglyceride and cholesterol in apoB-lipoproteins show diurnal rhythms. These rhythms are changed when animals are subje
ARRA: Diurnal Regulation of MTP and Plasma Lipids
The escalating obesity epidemic is now one of the most significant threats to human health in the 21st century. In this project, we will employ a novel approach to the empirical identification of novel candidate genes influencing body mass inde
Expression-Based Empirical Candidate Genes Influencing Body Mass Index
ADPKD is the most prevalent inherited renal disease, accounting for 4% of the ESRD population. Detection of renal cysts utilizing renal imaging has been the most common method of diagnosis of this disease however, cyst appearance is often delay
A Metabolomic Approach to Discovering Biomarkers for ADPKD
It is paramount in medical imaging to measure, compare, calibrate, register and analyze potentially deformed organ shapes with high accuracy and fidelity. However, this is extremely difficult due to the complicated shape of human organs. Differ
ARRA:  Conformal Geometry for Medical Imaging
Quantitative MRI of Microstructure and Iron Homeostasis in ADHD Brain  Attention-Deficit/Hyperactivity Disorder is the most studied condition in child psychiatry, reflecting its high prevalence and significant lifelong impairment. Despite progr
Quantitative MRI of Microstructure and Iron Homeostasis in ADHD Brain
The overall aim of this project is to develop novel conformal small-animal irradiator, suitable for studying genetic markers of radiation response and radiobiological models at therapeutic dose levels. There has been a revolution in functional
Regenerative medicine approaches for the reconstitution of missing or injured tissues and organs involves the use of scaffolds, cells, and bioactive molecules.  The use of biologic scaffolds seeded with cells is a common approach and several ap
Embryonic stem cell (ESC) differentiation is a potentially powerful approach for generating a renewable source of cells for regenerative medicine. It is known that the microenvironment greatly influences ESC differentiation and self-renewal. Mo
Microfluidic system for screening stem cell microenvironments
Knowledge of the mechano-electrochemical signals around the cells and solute transport within a tissue is crucial to understanding cell biology, tissue growth and remodeling in vivo or in vitro. Bioreactors are essential for tissue engineering
NOVEL QUANTITATIVE TECHNOLOGY FOR TISSUE ENGINEERING
Using micro-molded agarose, we have developed a novel and surprisingly easy system for creating 3D micro-tissues with complex shapes such as rods, toroids and honeycombs that are scaffold-free. 3D micro-tissues made in this way may have applica
DIRECTED SELF ASSEMBLY OF COMPLEX BRANCHING MICRO-TISSUES
DESCRIPTION (provided by applicant): When environmental exposure assessment studies provide feedback to the lay public, the resultant communications generally focus on the exposure assessment itself (e.g., serum levels) and not the relationship
Risk Communication for Environmental Exposure
SMITH-KETTLEWELL EYE RESEARCH INSTITUTE, THE
The fundamental goal of perception is to infer the structure of the world through an interpretation of temporal and spatial regularities in sensory stimulation that map onto structures in the environment such as objects and surfaces.  The goal
Area V4 is a key component of primate visual cortex that is involved in many aspects of 'intermediate' processing including higher-order shape processing, color constancy, and attention. V4 performs more complex computations than lower areas V1
Uveitis is a major cause of blindness. Anterior uveitis is approximately four times as common as posterior uveitis. Endotoxin-induced uveitis, a model first described by the PI nearly 30 years ago, has been a valuable tool to understand acute i
The overall goal of the proposed research is to understand how ErbB signaling regulates Abl/Arg and Src to control cell morphology, adhesion and movements during vertebrate development. Xenopus gastrulation will be used as the model system.   E
ERBB SIGNALING IN VERTEBRATE MORPHOGENESIS
Cytochrome COxidase (CcO) is an important enzyme involved in the electron transfer pathway in cellular respiration. CcO activates molecular oxygen to prevent the release of potentially toxic oxygen intermediates and at the same time, uses the f
ARRA QM/MM analysis of redox driven proton pumping
Most behavioral traits have complex bases and are the result of interactions between multiple genes and/or environments. Therefore, advancing our knowledge of human behavior will require an understanding of the genetic, epigenetic, and environm
Behavioral Genomics of the White-throated Sparrow
The central hypothesis of this proposal is that cysteine is a significant cause of oxidative stress without oxygen, and that reactive sulfur species (RSS) mediate this stress. Because some of the most notorious pathogens have a particular enzym
Myosins are the molecular motors essential for the viability of eukaryotic cells. In particular, non-muscular class V myosins are required for the inheritance, positioning, and transport of organelles in yeast, animals, and humans, whereas plan
MYOSIN-MEDIATED ORGANELLE TRAFFICKING IN PLANTS
Many proteins undergo post-translational acetylation of the ¿-amino group of lysine. Acetylation of histones and transcription factors, in competition with other modifications occurring on the same lysines, is well-established as a regulator o
Connexin acetylation: Impact on gap junction function and HDAC Inhibitor response Connexin acetylation
The proposed project should have a positive impact on human health; elucidating molecular mechanisms that regulate spermatogonial development may well lead to treatments and cures for male infertility, provide new targets for contraceptive deve
Molecular Mechanisms of Spermatogonial Development - ARRA Stimulus 2 Yr Resub
Recent breakthroughs in the pharmaceutical treatment of viral sexually transmitted infections (STI's) have dramatically improved the health and well-being of the infected. However, the treatment of such incurable infectious diseases raises uniq
The household production model remains the lens through which many social scientists and virtually all economists view time allocation within households. Adults' investments in their own human capital require time as well as money (e.g., going
The project will greatly advance scientific understanding of why and how marginalized heterosexual black men often seek out and engage in various forms of sexual behavior with multiple partners, and whether and how condoms and safer sex message
Multiple Sexual Partnering & HIV Risks among Low Income Heterosexual Black Men
The proposed project should have a positive impact on human health because elucidating molecular mechanisms that regulate sperm stem cell development will lead to treatments and cures for male infertility, provide new targets for contraceptive
Biology of ErbB Gene Family in Spermatogonial Development - ARRA Stimulus 2 Yr Resub
The objective of this proposed NIH RO1 is to expand the scope of a recently funded NIH grant titled 'A longitudinal MRI Study of Infants at Risk for Autism,' - (RO1 HD055741) and acquire 3-D chemical images of 6, 12 and 24 month-old siblings of
A Longitudinal 3-D MRSI Study of Infants at High Risk for Autism
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  The Micromorphology Laboratory in the Archaeology Department at Boston University is a unique facility in the United States and focuses on the mi
Improvements to Soil Micromorphology Laboratory
The ecological consequences of hybridization of asexual microbial symbiont  Many new plant and animal species arise from hybridization between different species. Although less well-studied, microbial species also hybridize and create new geneti
The ecological consequences of hybridization of asexual microbial symbionts
Mercury exists in the atmosphere as elemental mercury, gaseous oxidized mercury and particulate mercury. The atmosphere is an important pathway by which mercury is input to ecosystems. Mercury inputs may occur by way of wet and dry deposition.
Integrating Multiple Methods to Understand the Atmospheric Chemistry of Mercury and Mercury Dry Deposition from the Pacific to the Basin and Range
ABSTRACTThis award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). Understanding the barriers to reproduction between species is central to evolutionary biology. The evolution of reproductive barriers is a
Evolutionary Genetics of Conspecific Pollen Precedence in Yellow Monkeyflowers
A request is made to fund additional and back-up instrumentation on the R/V Marcus Langseth, a 235? Global seismic vessel with general oceanographic operated by Lamont-Doherty Earth Observatory of Columbia University as part of the University-N
This project models decision-making and learning in complex environments. One would expect most decision makers to be aware of such complexity and to realize that they have at best a limited understanding of the factors that determine the outco
The introduction of exotic species to native communities has caused considerable ecological and economic damage to agriculture, forestry, and fisheries. Research suggests this damage occurs in part due to a mismatch of evolutionary histories be
Resolution of Evolutionary Mismatches: The Ecological and Evolutionary Processes of Invasive Species Integration into Native Communities
This project proposes to develop, parameterize, and test phenological and evolutionary models for the two fungi associated with mountain pine beetle (MPB).  Coupled with an existing MPB phenology/fitness model, the fungal models will be used to
Phenological coupling and decoupling in a mutualism:  Terperature effects on a bark beetle host and two fungal symbionts.
Distinct organs, tissues and cells of plants can display different responses to environmental cues (e.g., during de-etiolation cotyledon growth is stimulated by light, whereas hypocotyl growth is inhibited by light). The hypothesis that organ-
Molecular Genetic Analysis of Spatial-Specific Phytochrome Responses in Arabidopsis Thaliana
A core challenge for ecologists is to develop frameworks to predict how complex natural communities and ecosystems will respond to environmental impacts such as species extinction and global change. Because ecological interactions are comprised
LTREB:  ECOLOGICAL DYNAMICS IN AN EXPERIMENTALLY-TRACTABLE NATURAL ECOSYSTEMS
The evolutionary adaptation to polar climates can provide a model for adaptations to climate changes in general. Today's frigid polar waters are inhospitable for most bony fishes, but some can live in freezing waters because they have evolved a
Evolutionary Origin and History of Antifreeze Glycoprotein Gene in the Northern Cod Fishes (Gadidae): Creating Sense from Non-Sense DNA
This project seeks to develop and demonstrate the capability of a Pacific Area Climate Monitoring and Analysis Network (PACMAN). PACMAN is expected to yield a more reliable understanding of the impacts of climate warming on fresh water resource
Collaborative Research: PACMAN - Cyberinfrastructure for Discovering Climate Change Impacts on Water Resources across Alaska and the Hawaiian Islands
Summary 	Aquatic insects play critical ecological roles and are of practical importance due to their widespread use in biomonitoring programs, yet their physiology is poorly understood. This research program will use a phylogenetically based, c
Comparative Strategies of Ion Trafficking and Antioxidant Physiology in Stream Insects: A Phylogenetic Approach
This project will evaluate the basic factors that allow ammonia oxidizing bacteria to respond to stress. An ecological framework based in differential gene expression at the community level will be integrated with deterministic mathematical mod
MSB - Investigating the Relationship Between Structural Diversity and Functional Resilience to Stress in Ammonia-Oxidizers
This study investigates the molecular mechanisms by which critical genes are regulated in the developing brain. Exposure to the hormone estrogen during development is critical for establishing long-term structural and functional aspects of the
Developmental regulation of estrogen receptor alpha by spigenetic modification
Eastern Dakota Housing Alliance (EDHA) will use these funds to provide loan financing that may be more flexible than other sources and to leverage resources for financially feasible affordable housing. Financing capital will make loans availabl
Community Loan Fund for Affordable Housing
BROOKLYN COOPERATIVE FEDERAL CREDIT UNION
The purpose of the award is to support Brooklyn Cooperative Federal Credit Union to offer fair and affordable financial and development services to further economic development in two of New York City's poorest, most under-banked neighborhoods,
Brooklyn Cooperative FCU:  Strengthening Capacity to Deliver Financial Services to the Underbanked
This CDFI Award has enabled Community Loan Fund of New Jersey, Inc. to deploy capital to assist in the mitigation of the foreclosure crisis in New Jersey. The Award supported an innovative program that has raised and deployed capital to purchas
Provided financing and development services to enable residents of manufactured housing parks to become resident-owners of these facilities.  The award was used to expand our lending activities.
Manufactured Housing Parks Resident Ownership
Assistance from the CDFI Fund allowed Santa Cruz Community Credit Union (SCCCU) to increase access to capital for low-income and underserved communities within Santa Cruz County, including the growing Latino population. SCCCU provided microente
Small Business and Affordable Housing Lending
SPRINGFIELD NEIGHBORHOOD HOUSING SERVICES, INC.
Financial Assistance Award of $600,000 aided the organization in providing counseling and educational services to its target market.  The award also helped to preserve jobs within the organization.
Provided 1st and 2nd mortgages to homebuyers as well as pre and post purchase counseling and education
Alternatives Federal Credit Union received a $2 million grant from the Community Development Financial Institutions (CDFI) Fund of the U.S. Treasury Department. Alternatives is a community development credit union based in Ithaca, New York, whi
The purpose of the grant award is to:  1) Hire a new loan officer/business counselor to bolster CAMBA Economic Development Corporation's capacity to continue to servicing existing loan clients as well as to better identify and service new loan
CAMBA Economic Development Corporation Mico Loan Fund
LUMMI COMMUNITY DEVELOPMENT FINANCIAL INSTITUTION
Lummi CDFI provides development services and technical assistance to Native clients interested in entrepreneurship and/or small business development.  Financial products are offered through a microenterprise revolving loan fund and an opportuni
Lummi Community Development Financial Institution
The long-term goal of this activity is to define novel, critical components required for the assembly of photosynthetic membranes.  Photosynthesis is the major mechanism of solar energy capture in the biosphere, providing organic carbon for f
(ARRA) The involvement of thiol-metabolizing pathways in thylakoid biogenesis
Collaberative research: Branching in chloridoid grasses: phylogeny and inflorescence diversification
The central nervous system (CNS) is a structure of immense complexity and intricacy, whose overall architecture has been  conserved throughout vertebrate evolution. The molecular and cellular mechanisms by which the three-dimensional (3D) struc
(ARRA) The role of Protocadherin-19 in brain morphogenesis
Cooperative behavior is a common trait among animals, from films of bacteria, to flocks of birds, to schools of whales. Observations of such coordination between individuals have inspired computer scientists and roboticists to try to build swar
ARRA: RHEOLOGY OF ANTS: STRUCTURAL PROPERTIES OF COOPERATIVE NETWORKS
The development of multicellular animals from a single-celled fertilized egg is a complex process that requires extensive communication between enormous numbers of cells. It is the long-term goal of this research to better understand how cellul
Role of Unpaired3 in Janus kinase signaling
'Mechanical Coupling Between Hair Cells of the Inner Ear' The sense of hearing plays a crucial role in our lives, as it helps us orient ourselves in space and communicate with each other; nevertheless, it remains one of the least understood of
MECHANICAL COUPLING BETWEEN HAIR CELLS OF THE INNER EAR
Title: Multiplex Analysis of Boundary Formation in the Drosophila Embryo.  Description:  There are two major tasks for this award.  The first is to obtain high quality multiplex in situ hybridization data from Drosophila embryos and the second
Multiplex analysis of boundary formation in the Drosophila embryo
This grant funds two long run research projects examining different aspects of worker motivation. One involves looking at how different incentive schemes in the workplace affect employee motivation as well as how they might affect self selectio
Collaborative Research: Incentives in the Workplace - An Experimental Examination of How Wage Differences Across Time and Among Peers Affect Productivity and Self-Selection
Political psychology is a thriving field of inquiry with roots in political science and connections to a range of other social sciences. Political psychologists attempt to understand the psychological underpinnings, roots, and consequences of p
2009 Summer Institute in Political Psychology
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). Little is currently known about how human and animal brains differ. While the human brain is unusually large, it is also known that even small str
The role of cortical Neurotransmitter Systems in Human and Nonhuman Primate Brain Evolution
Multiple lines of evidence imply that the Early Triassic was a time of elevated atmospheric CO2 most likely resulting from the extreme volcanism of the Siberian Traps. At the same time, metazoan reefs disappeared from the fossil record until th
Collaborative Research: New Chemo- and Biostratigraphic Framework for the Lower Triassic of the Western US: Towards a high-resolution understaniding of Early Triassic events
Everyday spatial behaviors in geographic space are essential activities in a person's life. Researchers have not yet developed instruments that sufficiently examine and evaluate these spatial behaviors, which include, among others, wayfinding,
Development and Assessment of Self-Assessed Scales for Everyday Environmental Knowledge (SEEK)
Office of Research, University of California
Intellectual merit of proposed research activity: Inflation is one of the most used concepts by economists, with a search for the term in research databases yielding thousands of matches. Most work in the area of price indices uses static model
This study examines the interrelationships of feeding behavior, food texture and jaw bone structure in 8 monkey species. The research goals are 1) to improve understanding of the influence of physiological activity on bone structure generally a
(ARRA) Collaborative research: Functional and ecological correlates of bone material variation in cercopithecoid mandibles.
The root systems of terrestrial plants not only obtain nutrients and water, but provide critical physical support for the above ground portions of the plants.  Some modern marine organisms, including algae and invertebrates, also have anchoring
Comparative Paleobiomechanics Of Holdfasts In Soft Substrates
This project will improve our ability to predict the access of solar energetic protons to Earth's magnetosphere and ionosphere. Solar energetic particle (SEP) events have strong space weather impacts and can change the radiation environment in
NSWP: Solar Energetic Particles in Geospace: Numerical Model Development and Validation
This Long-Term Research in Environmental Biology project capitalizes on 35 years of existing data to investigate how climate change is affecting the phenology (timing) and abundance of flowering by nearly 100 species of alpine wildflowers. Rese
LTREB: Drivers and consequences of phenological change at high altitudes
The Earth's critical zone is where water, atmosphere, ecosystems and soils interact on a geomorphic and geologic template, and extends from bedrock to the atmospheric boundary layer. Process understanding of erosion, weathering, soil formation,
Aquiring Airborne Lidar Data To Study Hydrologic, Geomorphologic, and Geochemical Processes at Three Critical Zone Observatories (CZO)
Title: MRI: Development of a New Instrument to Observe Isotopic Fluxes of CH4 and CO2 from Arctic Melt Regions, to Link Carbon Fluxes, Climate Feedbacks and Sea Level Rise. New developments in the physical sciences are poised to make critically
MRI: Development of a New Instrument to Observe Isotopic Fluxes of CH4 and CO2 from Arctic Melt Regions, to Link Carbon Fluxes, Climate Feedbacks and Sea Level Rise
This is a proposal to construct and test a liquid hydrogen target at Ursinus College for use with fast rare isotope beams. The design is based on an existing target developed at RIKEN in Japan. Drawings and technical details of the RIKEN target
MRI: development of a liquid hydrogen target for use with rare isotope beams
The combined use of microscopy and high-resolution fluorescence imaging is a fundamental tool for exploration of the physical and biological world. This Major Research Instrumentation grant from the NSF provides the Dartmouth community with a s
MRI: Acquisition of a multi-photon imaging and electrophysiology rig
This National Science Foundation award through the Major Research Instrumentation program will allow the purchase of a scanning electron microscope (SEM) that will expand the imaging and micro-quantitative analysis capabilities of Whitman Colle
MRI: Acquisition of an Environmental Scanning Electron Microscope (SEM) for Multidisciplinary Research and Undergradutate Research Training at Whitman College
Technical Summary: This project aims to develop a multimode optical microscope which will simultaneously reveal the structure and dynamics of soft and biological materials from various perspectives and across multiple length scales. The propose
MRI-Consortium: Development of a Multimode Microscope for Imaging Structure and Dynamics of Soft Materials
Funding was provided to acquire a Matrix-Assisted Laser Desorption/Ionization Tandem Time-of-Flight Mass Spectrometer (MALDI TOF/TOF MS) equipped with a LC-MALDI spotting system for general user access for research, education, and training. The
MRI: Acquistion of a Matrix-Assisted Laser Desorption/Ionization Tandem Time-of-Flight Mass Spectrometer
This MRI requests a Cell-Scale Biotester 5000 biaxial materials testing system, Applied Biosystems (ABI) real-time polymerase chain reaction (RT-PCR) analysis suite, and a Nikon Ti-E inverted C1 confocal laser scanning microscope. The Cell-Scal
MRI:  Acquisition of Instrumentation for Enhancement of Undergraduate Resarch and Pedagogy in Molecular Bioengineering
Technical Summary: Static and dynamic light scattering provide real-time, noninvasive characterization of molecular masses and/or particle sizes. They are powerful techniques for characterizing materials such as polymer dispersion, pigments, co
Acquisition of Light Scattering Instruments for Nanoparticle Characterization
With this award from the Major Research Instrumentation (MRI) program, the Ohio Laboratory for Kinetic Spectrometry and the Center for Photochemical Sciences at Bowling Green State University will acquire ultrafast spectroscopy instrumentation.
MRI: Acquistion of Equipment Enhancing the Ultrafast Spectroscopy Capabilities of the Center for Photochemical Sciences at BGSU
Funds from this grant will support the acquisition of a variable pressure cell equipped scanning electron microscope (VP-SEM) for geoscience research and education at Portland State University (PSU). The instrument will immediately impact the r
Acquisition of an Analytical, Variable-pressure Scanning Electron Microscope for Geoscience Research and Education at Portland State University
This proposal will fund the purchase of one Thermo Scientific LTQ Velos Orbitrap mass spectrometer for quantifying and describing proteins and their modifications. Being able to do such work is a fundamental component for understanding the func
MRI-Acquisition of Integrated Infrastructure Enabling Multidisciplinary Research in Systems Biology
This Major Research Instrumentation (MRI)award funds the acquisition of a Genome Sequencer FLX System from 454 Life Sciences and Roche Applied Science to help meet the needs of an expanding group of genomics researchers at University of Texas A
MRI: Acquisition of a Genome Sequencer FLX for High Throughput Sequencing and Genotyping in Genomics Research and Student Training
Funding is requested for two custom configured, versatile Atomic Force Microscope (AFM) instruments such as the Veeco BioScope II and MultiMode, which can perform all major scanning probe and force measurement techniques along with combined AFM
MRI-Acquisition of Atomic Force Microscopes for Cross-Disciplinary Materials Research and Education
This collaborative project, developing a mobile, open, and all-layers programmable platform for wireless communication systems research, supports the design, development, and dissemination of a community platform instrument, for collaborative a
Technical Summary: There is an emerging need to create meso-, micro-, and nano-scale structures on samples with arbitrary topography. This capability would enable the realization of new devices such as: sensors for vector quantities, CCD camera
ARRA-MRI: Development of a Complex Topography Phtolithography Tool for Micro-patterning on Non-Flat
Investigators will develop a new kind of scanning probe microscope, based upon the dielectrophoretic force. The microscope that they will develop will allow the team to probe the surfaces of nanoscopic and biological samples without contact of
Development of a Dielectrophoretic Force Scanning Probe Microscope for Non-Contact Biological Imaging
Intraventricular Cooling Catheter This Small Business Innovation Research Phase II project will build upon the success demonstrated in the Phase I program and further develop the Intraventricular Cooling Catheter whose purpose is to induce loca
The Cooperative Congressional Election Study is a collaboration of research teams from over 50 universities and colleges. Collectively these research teams have fielded national, stratified-sample surveys of 35,000 persons in 2006 and 37,000 pe
The 2010 Cooperative Congressional Election Study
This award is funded under the ARRA of 2009 (Public Law 111-5). This Small Business Innovation Research (SBIR) Phase II project involves development of real-time algorithms for Optical Character Recognition (OCR) from documents. This RT/OCR sys
SBIR Phase II: Real time, Accurate OCR from Documents using Intra- and
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).   What do babies learn first -- sounds or words? The standard view is that infants learn sounds first. In order to represent words most efficientl
Interactions between Word and Speech Sound Categorization in Language Acquisition
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  Real-world decisions utilize both sensory evidence and 'top-down' signals. When buying a house, for example, sensory evidence might consist of th
Top-down Signals for Eye Movements and Perception
Collaborative Research: robobees: A convergance of body, brain and colony
This proposal supports the acquisition of a UIC, Inc. Carbon Analyzer system for determination of concentrations of total carbon, total inorganic carbon, and total organic carbon in sedimentary materials. The instrument will support the work of
Acquisition of a Carbon Analyzer to Support Research in Sedimentary Systems
The PI will spend one academic year at the National Weather Center (NWC), on the campus of the University of Oklahoma. The PI will gain experience in the acquisition and interpretation of radar data, and enhance his collaborations with research
One year in National Weather Center: Mathematical theory in radar image
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).Organic matter diagenesis, including protein diagenesis, is an important area for understanding the fate of sinking marine materials as well as the
Linking Protein Degradation to Peptide and Amino Acid Compositions in Sinking Particles and Marine Sediments
This International Research Experiences for Students(IRES) project, funded under the American Recovery and Reinvestment Act, provides an intensive summer experience for US undergraduate engineering students to develop improved methods to assess
IRES:  Sustainable Development of Water and Sanitation Systems in Rural Honduras
Collaborative Research: Topology-Aware MPI Communication and Scheduling for Petascale Systems
Deciphering the origins of the giant large igneous provinces is a critical element for understanding mantle dynamics and its relation to terrestrial magmatism. Among a dozen or so large oceanic plateaus in the oceans Shatsky Rise is an importan
Collaborative Research: Geophysical Constraints on Mechanisms of Ocean Plateau Formation from Shatsky Rise, Northwest Pacific
Sexually-selected traits, such as horns, spurs, and bright feathers have attracted the notice of humans for centuries. During recent decades, knowledge of the processes of sexual selection has grown dramatically, yet much is still unknown. One
Selection in Heterogeneous Environments: a Multi-Trait Perspective
This research addresses a multidisciplinary challenge at the intersection of sensing, environmental engineering and geotechnical engineering focused on obtaining valid and representative measurements of chlorinated solvents in the geoenvironm
Geoenvironmental Influences on Raman Spectroscopic Monitoring of Chlorianted Solvents
Chemically-amplified resists are required for high-throughput patterning of integrated circuits, but recent experimental and theoretical reports suggest that these systems cannot simultaneously achieve the required resolution, sensitivity, and
BRIGE: Measurements of Image Formation in Chemically-Amplified Resists
This research project integrates experiments and modeling to develop physics-based predictive models for the problem of room temperature creep in nanocrystalline metallic films. The novel experiments aim at extracting directly the grain-boundar
Experiments and Models on Room Temperature Creep of Nanocrystalline Metallic Films
The Laurentian Great Lakes are a valuable regional resource and an immense reservoir of planetary fresh water.  Two major questions will be addressed in this proposed project.  First, what are the principal biogeochemical control points that ti
The current research in Bayesian model prediction and validation of computer models mainly focuses on computer experiments with single output and fixed input variables. The proposed research focuses on Bayesian approach for calibration, validat
ARRA: COLLABORATIVE RES: VALIDATION, CALIBRATION, AND PREDICTION OF COMPUTER MODELS WITH FUNCTIONAL OUTPUT
The research objective of this project is to construct an analytical framework to reduce uncertainty in forecasts of hurricane intensity by optimally targeting a coordinated observing network of unmanned aircraft using ensemble-based adaptive s
Collaborative Research: Targeting Observations of Tropical Cyclones Using Cooperative Control of Unmanned Aircraft
Optical trap-assisted nanolithography is a novel technique providing high resolution nanoscale rapid prototyping over different types of surfaces. Small plastic beads, used as near-field lenses for pulsed-laser processing, are placed in close p
Self-positioning Microspheres for Direct-write Nanolithography using Bessel Beam Optical Traps
River inputs play a significant role in the geochemistry of the global oceans. Rivers provide a significant source of nutrients, organic matter and suspended sediment to coastal shelves and the open ocean. The delivery of high nutrient loads to
Assessing the Impact of Developing-World Land Use on Riverine Organic Carbon Delivery to the Ocean
Coastal upwelling systems are oceanic regions of great importance with regard to productivity, air-sea carbon dioxide exchange, and carbon sequestration, as well as economically and ecologically valuable fisheries. In the California Current Sys
Reactive iron supply to shelf sediments and surface waters of the California Current System
This proposal is for acquisition of a tunable diode laser system.  The unit will be used for research on atmospheric vapor transport, and will be used intensively by Professors Galewsky and Sharp, as well as Ph.D. student Leah Johnson.
Acquisition of a tunable diode laser absorption spectroscopic isotope analyzer and peripheral induction furnace
This award will fund acquisition of a liquid oxygen isotope analyzer. The device is a reasonably new instrument relying on cavity ringdown spectroscopy. Precision specifications for this instrument are published at 0.1 permil and 0.3 permil for
(ARRA) Acquisition of a liquid water isotope analyzer for hydrological, glaciological and geochemical research
Granted funds will support establishment of a prototype Hydrologic Measurement Facility to be named the Center for Multiscale Sensing of the Environment (CMSE), allowing for the first time broad community access to fiber optic Raman temperature
Collaborative Research: Facility Support: Transformation of Distributed Environmental Sensing
This Small Business Technology Transfer (STTR) Phase I project addresses unmet analysis needs of froth flotation, a separations process widely used in the mining industry to separate worthless gangue from desired mineral particles. The goal of
STTR Phase I: Chemical Sensors for In situ Monitoring of Collector Chemicals in Complex Copper Mine Effluents
Millard Alexander of the University of Maryland is supported by an EAGER award from the Theoretical Chemistry and Computational program to conduct exploratory research on advanced methods for the study of chemical dynamics of multiple potentia
EAGER: Development of new methods for the study of chemical dynamics on multiple potential energy surfaces in complex chemical systems
This Small Business Innovation Research Phase I project seeks to develop advanced heat transfer fluids using nano-structured carbons.  Heat exchanger technologies having higher performance and lower cost are needed for improvement in cooling ef
Nanofluids for Improved Thermal Management
This Small Business Technology Transfer Phase I project will demonstrate the commercial feasibil-ity of metal oxide nanostructures, especially ZnO and TiO2, which offer unprecedented properties, suitable for a wide range of applications from th
STTR Phase I:  Cost-effective Fabrication and Patterning of Transparent Metal Oxide Nanostructures by Solution-based Laser Processing Technologies
This Small Business Technology Transfer Phase I project seeks to develop to develop a commercially viable, self-calibrating, piezoelectric micro-electro-mechanical systems (MEMS) microphone. The acoustical specifications of these microphones (m
STTR Phase I:  High Performance Piezoelectric MEMS Microphones
Granted funds will support acquisition of a Planar Laser-Induced Fluorescence (PLIF) imaging system and shock wave tube to study the dynamics of simulated volcanic eruptions in laboratory experiments. Laser-based multi-phase fluid dynamic diagn
Acquisition of Imaging Equipment to Understand the Dynamics of Explosive Volcanic Flows through Laboratory Experiments and Field Observations
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).930909DotyMicroorganisms that live within plants (endophytes) can dramatically enhance plant growth by increasing resistance to pathogens and stres
Nitrogen Fixation in Poplar:  Increased Efficiency of Bioenergy Crop Production
CPS:Small:Fundamental Advances in Control of Wireless Sensor and Robotic Networks       The objective of this project is to investigate fundamental issues in network control and distributed coordination of wireless sensor and robotic networks.
CPS: Small: Fundamental Advances in Control of Wireless Sensor and Robotic Networks
ELAINE KAUFMAN CULTURAL CENTER/LUCY MOSES SCHOOL FOR MUSIC A
The objective of this inter-disciplinary research is to develop new technologies to transform the streets of a city into a hybrid transportation/communication system, called the Intelligent Road (iRoad), where autonomous wireless devices are co
CPS: Small: Transforming a City's Transportation Infrastrucurre through an Embedded Pervasive Communication Network
Sprains of the knee ligaments are among the most common orthopedic injuries. They usually occur when the knee is forced beyond its normal range of motion, such as in a fall. They also happen when the knee experiences an impact, such as in a car
Micro-Mechanical Characterization of Damage in Ligaments
SenMater Technology, LLC is a newly founded small company located in Fayetteville, Arkansas. The mission of SenMater is to develop advanced sensing materials and materials-related novel technologies for electronic, photonics, medical and
Development of Aptamer-ssDNA Intelligent Hydrogel Materials for Magnetoelastic Detection of Avian Influenza
To support the preservation of jobs that are threatened by declines in philanthropic and other support during the current economic turndown.
This engineering education research award to James Madison University will integrate instruction in sustainability into design courses across three years of the undergraduate engineering curriculum. The project will develop methods for evaluati
IEECI Exploratory Grant:  Integrating Developmental Instruction in Sustainability Contexts into an Undergraduate Engineering Design Curriculum
The purpose of this proposal is to start a new I/UCRC 'Integration of Composites into Infrastructure (CICI)' with a focus on ushering applications and cost-effective rehabilitation schemes using composites in civil and military structures. The
Collaborative Research thru NSF I/UCRC Full Grant: Center for the Integration of Composites into Infrastructure (CICI)
Collaborative Research: I/UCRC on Grid-Connected Advanced Power Electronic Systems (GRAPES) The purpose of this I/UCRC is to develop the new knowledge, tools, hardware, and personnel that will be required to pervasively insert power electronics
Collaborative Research: I/UCRC on Grid-Connected Advanced Power Electronic Systems (GRAPES)
The Kenan Fellows Program for Curriculum and Leadership Development, housed at the Kenan Institute for Engineering, Technology, & Science on the North Carolina State University (NC State) campus, is partnering with school districts in 11 counti
Kenan Master Teaching Fellows: Linking Research Experiences and Curriculum Development with Leadership
This project is a planning grant with the ultimate goal of submitting a full proposal in spring 2010. The project involves science and mathematics educators, Los Angeles County Office of Education and an external evaluator. We will be determini
Developing Master Teachers in Mathematics and Science at California State University, Long Beach
The Portland State University (PSU) Robert Noyce Teacher Scholars Program, Phase II addresses the critical local and national need to expand the talent pool of teachers with science content knowledge, pedagogical skills and leadership capacity
Partnership for Science and Math Teacher Education, Phase II
ASSOCIATION OF INDEPENDENTS IN RADIO, INC.
To support the preservation of jobs that are threatened by decline in philanthropic and other support during the economic downturn.
SOUTHERN CALIFORNIA ASIAN AMERICAN STUDIES
To support the preservation of jobs that are threatened by declines in philanthropic and other support during the current economic downturn, as described in our application (A09-905094) and the approved project budget.
To support the preservation of jobs that are threatened by declines in philanthropic and other support during the current economic downturn, as described in our application (A09-906211) and the approved project budget.
The Department of Curriculum and Instruction and the Department of Mathematics at the University of Illinois at Urbana-Champaign (UIUC) are awarding Noyce Scholarships to 39 students, including 24 undergraduate mathematics majors and 15 postbac
Noyce: Preparing Excellence and Diversity in Secondary Mathematics Teachers for Illinois' High Schools Needs
This engineering education research award to Purdue University will employ researchers to develop a deeper understanding of key skills required by future engineers as well as assessment tools to measure these skills. Service-learning, which pre
Students' Understanding of Human Centered Design and the Impace of Service Learning
This engineering education research award to Virginia Polytechnic Institute and State University in collaboration with University of Tennessee Knoxville will study learning, knowledge sharing, and participation in open-source communities to bet
Collaborative Proposal (IEECI Exploratory): Identifying Practices and Tools to Promote Newcomer Participation in Cyberlearning Environments
This engineering education research award will study the progression of students through their choice of engineering major. In particular the study will address why students choose to enroll in one engineering discipline rather that another and
This engineering education research award to Syracuse University will employ researchers from the College of Engineering and Computer Science as well as College of Architecture to investigate new approaches to improved creative problem solving.
Inspiring Innovation: Merging Pedagogical Paradigms from Engineering and Architecture
This engineering education research award to Purdue University will study the attitudes and threshold concepts of first and second year engineering students towards the relationship between environmental sustainability and engineering. The stud
Engineering Students' Attitudes and Threshold Concepts Towards Sustainability and Engineering as Environmental career
This engineering education research award to Texas Engineering Experiment Station in collaboration with Saint Mary's University will employ researchers in the development of new methods and web-based tools to integrate design of automated manuf
Collaborative Research: Collaborative Learning Environment for Automated Manufacturing System Integration (CLE-ASI)
An innovative technique for improving seismic performance of steel beam-column connection with the advantages of the reduced beam section (RBS) connection, but with improved energy dissipation. Through a pilot study the concept is validated num
NEESR CR, An Innovative Seismic Performance Enhancement Technique For Steel Building Beam-Column Connections
The Division of Chemistry supports Michael Walter of California Institute of Technology (CalTech) as an American Competitiveness in Chemistry Fellow. Dr. Walter will investigate the preparation and characterization of metal treated aminophenylp
Metallo(4-aminophenyl)porphyrin Polymer Films on Si Microrod arrays for Photocatalytic Hydrogen Evolution & New Solar Energy Experiments for Students at John Muir High School
Professor Franz Geiger of Northwestern University is supported by the Analytical and Surface Chemistry Program in the Division of Chemistry to develop a label-free non-linear optical imaging voltmeter for interrogating fluid/solid interfaces. U
EAGER: Proposal for Nonlinear Optical Imaging of Interfacial Acid Base Chemistry
This is a RAPID project that sends an early career female researcher to participate in a unique, state-of-the-art, 3D seismic study of the central portion of the Mentawai segment of the Sumatran subduction zone to collect and interpret detailed
RAPID: Deep Seismic Investigation of Sumatran Subduction Zone Seismic Gap
'This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).'  This Nanotechnology Undergraduate Education (NUE) in Engineering program entitled 'NUE: A Nanotechnology Certificate Program for Engineering Un
ARRA NUE: A Nanotechnology Certificate Program for Engineering Undergraduates
This grant will initiate a new project on the design of catalysts that can harvest solar energy and relay this to the metal centers to promote the rate of reactions or to induce desirable selectivity effects. Specifically, ligands are designed
A key element is commodity governance, which encodes social and technical aspects of governance in cyberinfrastructure to create virtual units capable of operating, aggregating, and coordinating in a decentralized fashion. This is a deeply int
Collaborative Research: CSI Type II: Scaling Up: Introducing Community Governance into Community Earth Modeling
Autism Spectrum Disorder (ASD) is estimated to affect approximately 1 out of every 166 children around the world, with a prevalence rate that makes it the most common developmental disability. Conservative estimates report that in the US over 4
A Novel Quantitative Framework to Study Lack of Social Interactions in Autism
Arts and the American Recovery & Reinvestment ACt of 2009
Voluntary Virtual Organization (VVOs) have harnessed the collective problem solving abilities of diverse groups.  This project will study voluntary teaming in Massively Multiplayer Online Games (MMOGs), specifically collective story telling in
VOSS: Collaborative: Voluntary Virtual Organizations
In recent years, the use of geographically (and often globally) distributed teams to accomplish organizational tasks has become ubiquitous. One arena where the use of such teams is popular is in Information Systems Development. Interestingly, w
Understanding Work-Life Balance Issues of the Globally Distributed Software Development Workforce
Collaborative Research: Linking Researchers and Graduate Students through COSEE Tools &Services
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).A request is made to fund additional and back-up instrumentation on the R/V Thomas Thompson, a 274? general purpose Global research vessel and the
This NSF award is for Shipboard Science Support Equipment aboard the R/V Hugh R. Sharp. This award includes a ship anti-roll stabilization system, repair and upgrades to the existing Caley CTD system and an up-grade to the existing starboard tr
Shipboard Scientific Support Equipment CY 2009
The goal of this project is to design and implement a software toolkit and ready-to-go application plugins that are able to encode and understand the underlying meaning of data, information, and science concepts in a familiar vocabulary.  Both
STCI:A Semantic eScience Framework (SESF): Facilitating Next Generation Data Intensive Science
The proposal requests numerous Shipboard Scientific Support (SSSE) items for the vessels operated by the Lamont-Doherty Earth Observatory (LDEO); namely the R/V MARCUS LANGSETH. The requests specifically include items that have been recommended
This program involves the development of a new reactor that is designed to provide access to a new class of cluster materials.  Clusters of rare-earth elements are currently unknown and would represesent a major breakthrough in cluster science.
EAGER: Molecular Rare-Earth Clusters in Reduced Oxidation States
The National Science Foundation’s TeraGrid high-performance computing (HPC) network provides extensive support for massive computational science, typically conducted by scientists highly trained in HPC. TeraGrid’s strategic plan requires th
Instant-On Simulation Delivery: Helping TeraGrid Achieve its Wide and Open Strategic Goals
This is stimulus funding from the National Science Foundation, which will be used toward supporting student fellows in the NSF Graduate Research Fellowship Program. It will be disbursed over 3 years, so approximately $666,666/year, and is used
The NSF Graduate Research Fellowship Program (GRFP) helps ensure the vitality of the human resource base of science and engineering in the United States and reinforces its diversity. The program recognizes and supports outstanding graduate stud
No abstract available.  This is a Graduate Research Fellowship award covering academic years 2009 - 2012.
The spacetime discontinuous Galerkin (SDG) method is a new computational technology whose novel mathematical framework leads to algorithms that have the potential for signi?cant impact in a wide variety of application disciplines wherever high-
EAGER Proposal: Adaptive Spacetime Discontinuous Galerkin Methods in 3D x Time
More than one-half of the global human population now lives in cities. In the U.S., Sun Belt cities like Tampa are growing rapidly, but rapidly growing cities consume more natural resources than they produce. Urban ecosystems rely on the redist
ULTRA-Ex: Urban Development, Power Relations, and Water Redistribution as Drivers of Wetland Change in the Tampa Bay Region Socioecosystem
The aim of the proposed research is to explore cyber-infrastructure that will enable and promote large scale collaboration in building, maintaining, and using (towards discovery) scientific knowledge bases that are grounded in published literat
EAGER: Enabling collaboration in the creation of scientific databases from the published literature
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).The objective of this research project is to advance the vision of a universal bio-signal acquisition system-on-chip (SoC). Such a system would hav
EAGER: Ultra-low-power, Universal, Multi-rate Bio-signal Transceiver SoC for Medical Diagnois and Brain-Machine Interface Applications
This is a planning grant with the objective to encourage and assist the military veterans population in entering STEM fields of study (Science, Technology, Engineering, and Mathematics) through a national, geographically distributed, consortium
A Planning Grant Proposal for Transitioning America's Veterans to Science, Techology, Engineering and Mathematics (STEM) Academic Programs
Arts and the American Recovery and Reinvenstment Act of 2009
Highway Infrastructure Investment Grant: Areas with Population over 200K Population
Treatment as usual and peer engagement in teens with High Functioning Autism  --  Epidemiological studies now indicate that the prevalence of autism and related disorders may be as high as 1 in 150 children with nationwide estimates of th
Treatment as usual and peer engagement in teens with High Functioning Autism
This project is focused on discovering the mechanisms which act during early brain development to cause mental retardation in Down syndrome (DS).  The Aims include experiments to uncover why more inhibitory interneurons are produced in the cere
Forebrain development in Down Syndrome and in Ts65DN model mice
The overall propose is to understand the initial steps in stem cell differentiation. The expected outcome is to learn more information that will allow us to i) develop new markers to allow us to classify and purify unique populations of stem ce
POST-TRANSLATIONAL REGULATION OF EMBRYONIC STEM CELLS: A PROTEOMIC STUDY.
Here we investigate a novel antimicrobial approach using the metal gallium (Ga) as a 'Trojan horse' to disrupt bacterial Fe metabolism.  Ga has a nearly identical ionic radius as Fe, and many biologic systems are unable to distinguish Ga from F
Gallium, a potential new therapeutic for CF airway infections
The Specific Aims of the project are: 1. Optimize image quality of retrospectively gated Cardiac C-arm CT volume images from a sparse set of projections with the goal of achieving temporal resolution less than 250 ms, while maintaining the abil
C-ARM CT FOR GUIDENCE OF CARDIAC INTERVENTIONS
Circadian and daily rhythms regulate many aspects of physiology and behavior. Although a growing number of studies suggest that circadian disruptions may render organisms more susceptible to infection and cancer, the molecular links between the
Biology of the NK Cell Cytolytic Activity Rhythm
The recognition of the hierarchies of genetic pathways coordinating heart development remains incomplete, in part because of the difficulties to identify the critical cis-acting sequences that are required for the regionalized expression of gen
DISSECTING OF THE TBX20 REGULATORY NETWORK
Acute lung injury, sepsis, lung inflammation, and ventilator-induced lung injury are life-threatening conditions associated with lung vascular barrier dysfunction, which may lead to pulmonary edema. Increased levels of atrial natriuretic peptid
PROTECTIVE ROLE OF ANP IN THE MODELS OF ACUTE LUNG INJURY
Arterial disease (arteriosclerosis) is accelerated in the presence of hypertension, a major cardiovascular risk factor that affects more than 65 million people in the USA, resulting in health care costs of ~$110 billion annually. Despite signif
Determinants of arterial function in hypertension
The proposed research will study a novel approach for treating heart valve disease via the use of heart valve replacements with trileaflet polyurethane prostheses that are endothelial seeded using blood outgrowth endothelial cells (BOEC). We wi
BLOOD OUTGROWTH ENDOTHELIAL CELL SEEDING OF HEART VALVE LEAFLETS
Persons with abdominal obesity have a high prevalence of endothelial dysfunction, arterial stiffness, and left ventricular diastolic function, each an early marker of cardiovascular disease (CVD). Though diet and exercise are primary treatments
TWO DIETS WITH EXERCISE IN ABDOMINAL OBESITY: CARDIOVASCULAR EFFECTS
The mean time to reperfusion of acute myocardial infarction (AMI) patients in the USA is 3-4h.  The metabolic activity within the ischemic tissue over this period is a major determinant of outcome and is critically influenced by the glycemic an
JNK EXACERBATES ISCHEMIA/REPERFUSION INJURY IN HYPERGLYCEMIC SUBJECTS.
Driven by advances in electronic miniaturization, probe construction techniques and computing power, medical ultrasound is experiencing a trend toward smaller, lower cost systems with real-time volumetric imaging capabilities. These new attribu
Non-Invasive Hemodynamic Monitoring of Physiological Perameters
There are ~5 million heart failure patients in the United States. Over half are estimated to have diastolic heart failure or heart failure with normal or near normal left ventricular ejection fraction. Most diastolic heart failure patients are
NEUROHORMONAL BLOCKADE AND OUTCOMES IN DIASTOLIC HEART FAILURE
Millions of Americans develop chest pain suggestive of coronary heart disease each year and often require non-invasive diagnostic testing. However, currently available tests are imprecise, robust evidence regarding optimal test choice is limite
PROMISE Trial: Clinical Coordinating Center
We have made important progress on the Tol2 project since the revised application and the supplemental data were submitted in 2008. The most significant advance is the demonstration of germ line transmission of remobilized Tol2 transposons foll
TOL2-MEDIATED GENE AND ENHANCER TRAPPING IN XENOPUS TROPICALIS
The medical office visit is the foundation of medical care and one of the most important professional activities of primary care physicians who are often the only source of mental health services for older adults. Evidence continues to show tha
MENTAL HEALTH COMMUNICATION IN ELDERLY PRIMARY CARE VISITS AND ECONOMIC OUTCOMES
The long-range objective of the proposed research is to refine, evaluate, and disseminate an Internet-based intervention to prevent eating disorders (EDs) and comorbidities in college-age women. EDs are highly prevalent among college women and
2/2-PREVENTING EATING DISORDERS AND REDUCING COMORBIDITY
This proposal will focus on HIV infection studies with HIV-ADA and will not compare different HIV isolates.  Primary isolates will be performed in future studies.  The scope is limited to cystatins B/C and cathepsin B.  Includes studies of MDM
Modulation of Cystatins and Cathepsins in HIV-1 Neuropathogenesis
University of Puerto Rico Medical Sciences Campus
Schizophrenia is a devastating psychiatric illness arising in part from subtle defects in brain development. The Disrupted-In-Schizophrenia-1 (DISC1) gene is an example of a strong candidate gene for studying the pathogenesis of schizophrenia a
MUTANT DISC 1 AND ABNORMAL NEURODEVELOPMENT IN MENTAL ILLNESS
Although a wide range of environmental stimuli have been proposed to play a role in the pathogenesis of autism spectrum disorders, many of these stimuli have in common the ability to alter immune function. Since cytokines mediate the immune res
Maternal Immune Activation, Cytokines, and the Pathogenesis of Autism
3/5-ELUCIDATING THE GENETIC ARCHITECTURE OF AUTISM BY DEEP GENOMIC SEQUENCING
This study is designed to improve access to appropriate behavioral services for young children (ages 1 to 6 years) with autism spectrum disorders. The major research goal is to evaluate the effectiveness and efficiency of conducting behavioral
Behavioral Treatment for Autism in Community Settings Using a Telehealth Network
The sympathetic nervous system innervates a number of targets, including the heart, and sympathetic activity is a critical regulator of cardiac function. Sympathetic neurons form noradrenergic synapses onto heart cells resulting in excitation o
Regulation of neurotransmitter properties by target-derived neurotrophic factors
The organization of the neural network, or Central Pattern Generator (CPG), that organizes locomotor behavior in the rodent spinal cord, is poorly understood. We propose that the function of the CPG network depends not only on the pattern of sy
THE RODENT CENTRAL PATTERN GENERATOR FOR LOCOMOTION
This award was funded to support our ongoing effort to develop MRI image analysis software, called DtiStudio/MriStudio. This is a family of software to analyze MR images. The software was developed through collaboration between Drs. Mori and Mi
DTISTUDIO: RESOURCE SOFTWARE FOR DIFFUSION TENSOR IMAGING
It is currently estimated that in 2050, the cost of treating the aging population for dementia caused by various neurodegenerative diseases will consume the entire gross national product of the industrialized countries. Consequently, effective
This study addresses the mechanisms of regulation of neuronal gap junctions (electrical synapses) during development and traumatic brain injury and the role of gap junctions in traumatic brain injury. This research has clinical importance given
Regulation of Gap Junction Coupling During Development and Neuronal Injury
Approximately 40,000 Americans are diagnosed with brain tumors each year, with15-35% being glioblastoma multiforme (GBM), an aggressive primary brain tumor that has defied all existing therapeutic modalities. Treatment of brain tumors normally
MION FOR SYNCHRONIZED MRI AND DRUG THERAPY OF BRAIN TUMOR
Spinal cord injury disrupts the connections between the brain and spinal cord, often resulting in the loss of sensory and motor function below the lesion site. The most important reason for such permanent functional deficits is the failure of i
Promoting axon regneration and functional recovery after spinal cord injury
This proposal entitled 'Dynamic Regulation of shank3 and ASD' examines the molecular mechanisms that link human mutations of shank3 with Autism Spectrum Disorder (ASD). Mutations of the open reading frame of shank3 have been identified in multi
The goal of the proposed project is to develop a community driven, open source Disease Ontology (DO) that can be used to link disparate datasets through disease concepts. We will provide a computable structure of inheritable, environmental and
Disease Ontology: An Open Biomedical Ontology for Disease
The health benefits of the proposed research include the potential to discover new and effective glycotherapeutics to fight bacterial infections in humans. Other benefits to the biomedical community include the discovery of new effective synthe
Synthetic saccharides to study immunological properties of Streptococcus pneumoniae serogroup 6
The overarching goal of the proposed study is to improve communication among clinicians, patients, and family caregivers about a diagnosis of dementia. Specific aims. 1) Characterize physician, patient, and companion behaviors during a dementia
DISCLOSING A DEMENTIA DIAGNOSIS:  ANALYSIS OF A TRIADIC HEALTHCARE ENCOUNTER
White Matter Lesions (WML) of aging are commonly seen on MRI scans and show as diffuse or punctate lesions with a predilection to affect periventricular areas. Several studies have shown that WML are associated with increased risk of falls in o
WHITE MATTER LESIONS AND CORTICAL SEROTONERGIC DEAFFERENTATION IN OLDER ADULTS
Long lasting vaccination memory that is effective in both healthy and at-risk individuals is an important public health goal.  This work seeks to improve the quality and persistence of such immune memory by adding drugs that decrease the death
Pharmacological Vaccine Adjuvants:  Analysis of Immune Responses to Vaccines
This project will use specimens and epidemiological data  collected from a series of field gonorrhea intervention projects conductied in Baltimore.  The project will develop a method for typing gonococcal isolates (organisms) which uses prote
A herpesvirus, referred to as LHV-4, was found to be associated with a disease affecting over half of the 55 rabbits on a farm near Anchorage, Alaska. About 28 percent of the affected animals died or were euthanized because of the severity of t
Characterization of a Novel Rabbit Herpes Simplexvirus: A Possible Model for Understanding Latency
Stenotrophomonas maltophilia is an environmental bacterium that is implicated in an increasing spectrum of human disease, including infections of the lung, blood, heart, urinary tract, CNS, eyes, skin, and soft tissue. The respiratory tract is
Virulence Factors of Stenotrophomonas Maltophilia
antigens that have been previously encountered in the skin is an important consideration in developing vaccines for agents that attack through the skin, and in developing treatments for immune diseases that target the skin, such as psoriasis.
Loading Skin Derived Antigen on Dendritic Cells in Vivo for T Responses in Vitro
LOMA LINDA VETERANS ASSOCIATION FOR RESEARCH AND EDUCATION
Developing strategies for diagnosis and treatments of the gender specific osteoporosis, which is a major health problem, requires good understanding of the genetic basis of bone development. The objectives of the proposed project is to identify
Identification of Gender Specific BMD Candidate Gene in Chromosome 1
Medical research to determine whether low levels of caveolin-1 in their monocytes, fibrocytes, and fibroblasts play a critical role in the susceptibility of idiopathic pulmonary fibrosis and scleroderma patients to lung fibrosis.
Caveolin-1 Regulation of Altered Functions of Scleroderma Fibrocytes
The differentiation of muscle precursor cells into contractile skeletal muscle fibers is necessary for normal muscle development and regeneration and, when defective, leads to musculoskeletal diseases such as muscular dystrophies and muscle tum
Pbx Homeodomain Proteins in Skeletal Muscle Differentiation
Epidemiological studies and clinical observations suggest that persistent chronic inflammation is important in prostate carcinogenesis. The chronic inflammatory lesions frequently observed in prostate tissue biopsies and radical prostatectomy s
FOXO: A Target for Prostate Cancer Prevention
Survivors of cancer diagnosed during young adulthood (i.e., diagnosed between 18-39 years of age) (SCDYA) are an understudied population and likely have unique concerns and needs and face different challenges than survivors of either childhood
A Population-based Controlled Investigation of QOL and Health Behaviors Among Sur
Tobacco smoking decreases food intake and weight gain and a high percentage of smokers started smoking to lose weight. Conversely, smoking cessation has been associated with increased food intake and weight gain. Evidence suggests that smoking
Nictone Dependence and central Adiposity Signaling
Although advances in the treatment of alcohol and drug dependence have led to major reductions in substance use, relapse remains a prevalent national problem. Commonly espoused theories of relapse and relapse prevention have long suggested that
Ecological Momentary Assessment of Relapse to Substance Use Following Treatment
Methamphetamine (METH) abuse and dependence represent major mental health and law enforcement problems in the US and abroad. PET studies consistently showed chronic reduction in dopamine transporter (DAT) density in the striatum of methamphetam
New Dopamine Transporter MRI Nanoprobes for Addiction Research
Novel class of peptidomimetics, and cyclic peptidomimetics have become appealing targets for the design of therapeutic agents with increased pharmacological activities. Therapeutic potential and demand of opioid analgesics have initiated numero
Innovative approaches to oligoheterocyclic peptidomimetics
Stimulant abuse (including both cocaine and amphetamines) is a serious public health problem. There are thought to be over 3 million current users of these drugs in the United States, and these drugs account for numerous emergency room visits e
Pawhuskins: Potential Treatments for Stimulant Abuse
The overall goal of this project is to examine the effects of cocaine dependency on renal physiology in African Americans (AAs). Cocaine-dependent AAs are at risk for sub-clinical renal damage resulting from cocaine use, yet little data exists
DESCRIPTION (provided by applicant): Food insecurity and overweight pose significant risks to the optimal development of low income children. While insufficient consumption of high-quality nutritious food and/or excessive consumption of poor qu
Maternal depression, family food behavior, and child nutritional health.
By early childhood, children who will later develop a primary psychotic disorder are already demonstrating many of the deficits that are closely associated with the disease in the adult. For example, even though diagnostic symptomotology may be
Attention and Smooth Pursuit in Infants with a Family History of Psychosis
Although state and local mandatory helmet laws have become widespread in the US, there is almost no information on whether such regulations actually decrease injuries from bicycle-related accidents. The first aim is to use pooled, annual, hospi
ARRA Funded:  Effectiveness of Bicycle Helmet Laws in Preventing Injuries Among Youth
Of 5.7 million stroke survivors in the United States, up to 90% may have visuospatial deficits, linked to poor rehabilitation outcomes, an increase of clinical morbidity, and impairments in competent driving, shopping, sports, computer/internet
Visuospatial Rehabilitation after Right Hemisphere Stroke
Pulmonary hypertension (PH) is a life-threatening condition which can occur in association with many diseases, including chronic obstructive pulmonary disease (COPD) and idiopathic pulmonary fibrosis (IPF).  PH occurring in isolation, with char
Molecular Mechanisms of Pulmonary Hypertension in COPD
Terminal airway occlusion by hypersecretive mucus is a major manifestation in chronic obstructive pulmonary disease (COPD). In the cystic fibrosis lung, a genotype of COPD, hyperactive ENaC has already been proved to be a fundamental mechanism
ENaC Expression in Human COPD Airway and Lung Tissues
The difference between the number of proteins with known sequence and those with wellstudied function (sequence-function gap) is growing daily. Bioinformatics bridges this gap mostly through homology-based inferences of the type: assume that th
Novel method to identify competing protein-protein binders
Human DNA sequence differs among individuals and the most common variations are known as single nucleotide polymorphisms, or SNPs. Studies have shown that non-synonymous coding SNPs (nsSNPs - SNPs occurring in protein coding regions which lead
The Effect of Single Nucleotide Polymorphisms on Protein Structure and Interaction
There has been growing interest in recent years in developing methods that automatically identify Gene Ontology (GO) concepts in the unstructured text of scientific articles. This interest is motivated in part by the need to automate the task o
Beyond information extraction: Identifying Gene Ontology concepts in text
The revised application is in response to PA-06-543, 'Mechanisms, Models, Measurement, & Management in Pain Research (R03).' Consistent with this program announcement, we aim to test hypotheses about the developmental pathways to comorbid pain
DEVELOPMENTAL COMORBIDITY OF PAIN AND DEPRESSION IN PREADOLESCENT GIRLS
Although Parkinson's disease (PD) was first described in 1817, the cause still remains obscure. A large body of experimental evidence indicates that destruction of dopaminergic neurons may result from a series of inter-related mechanisms involv
RISK OF PARKINSON'S DISEASES ASSOCIATED WITH ASPIRIN AND OTHER NSAIDS
Rett syndrome is a severe neurological disorder causing progressive loss of motor and language skills in girls. There is no cure for the disease, and existing treatments are very limited.  Recent studies have demonstrated that mutations in the
This project represents an opportunity to develop protective treatments for glutaric aciduria that may be relevent to other childhood metabolic disorders.Glutaryl-coenzyme A dehydrogenase (GCDH) deficiency is an inherited disorder of lysine and
DIETARY INTERVENTION AND MITOCHONDRIAL TOXICITY IN AGE-DEPENDENT MODEL OF GLUTARIC ACIDEMIA
Spontaneous and ENU-induced mouse mutants are a tremendously valuable resource for their ability to model human disease. The study of these mutants has provided new insights into basic clinically relevant biological mechanisms, which would not
TIPPY A NOVEL MOUSE MODEL FOR HUMAN ATAXIA EPILEPSY
DESCRIPTION (provided by applicant): Deep brain stimulation (DBS) treats the cardinal symptoms of Parkinson's disease (PD) including bradykinesia, rigidity, and tremor, and the efficacy of DBS is strongly dependent on finding stimulation par
TIME COURSE OF PARKINSON'S SYMPTOMS IN RESPONSE TO DEEP BRAIN STIMULATION
The proposed research will enhance our understanding of how and when endocrine-disrupting chemicals (EDCs) affect the immune system, and will form the basis for assessment of prenatal immune impacts of EDCs and for strategies to prevent immune
Prenatal Developmental Immunotoxicity of Diethylstilbestrol and Methoxychlor
Defects in intermediate filament (IF) proteins that normally form stress resistant networks in cells, and contribute to their architectural integrity and cellular function, are linked to a number of human disease conditions, including congenita
A Genetic Analysis of Intermediate Filament Function in C. elegans
The combination of high resolution assays in genomics with microscopic imaging has been used for the detection of complex chromosomal rearrangements, a significant but difficult problem in prenatal and postnatal diagnosis, birth defect detectio
Accurate Detection of Chromosomal Abnormalities with Multi-color Image Processing
Interactions of C-Reactive Protein Isoforms With Oxidized Lipid Membranes Abstract: C-reactive protein (CRP) rises in serum in response to inflammation and is a promising marker for identifying patients at risk for cardiovascular disease (CVD).
Interactions of C- Reactive Protein Isoforms With Oxidized Lipid Membranes
Sexual reproduction in diploid eukaryotes involves formation of haploid gametes through a specialized cell division known as meiosis. Fusion of two haploid gametes at fertilization recreates diploidy in the next generation. Accurate segregation
Comparative and functional preteomics of geremline chromatic in C. elegans
DESCRIPTION (provided by applicant): Few processes in biology hold the same degree of fascination as the transformation of a single fertilized egg into a fully differentiated adult organism. What are the genetic mechanisms that physically build
THE DEVELOPMENTAL FUNCTION AND EVOLUTIONARY HISTORY OF THE DROSOPHILA FOLDED GASTRULATION GENE
The overarching goal of this project is to better understand the ways in which cognitive and emotional self-regulation are disrupted in depression. When faced with unfavorable situations, people with depression are unable to implement adaptive
Cognitive and Emotional Self-Regulation in Depression
The liver is the largest organ in the body. It is involved in a myriad of metabolic processes required for body homeostasis and can also detoxify harmful chemicals. The liver receives blood from the hepatic portal vein and the hepatic artery. T
A Microfluidic-Platform Mini-Liver System for Human Liver Biology
Alternative splicing is an important level of gene regulation and a major source of proteome diversity in humans and other mammals. At least 74% of human genes express multiple mRNAs through alternative splicing of exons or exon segments. Dereg
Elucidating CIS-Acting Elements Regulating Alcohol-Induced Alternative Splicing
Research on lymphostromal interactions during the thymic aging--Aging causes thymic involution, which decreases thymic lymphopoiesis and exhausts the naïve T-cell pool, constricting diversity of T-cell receptor repertoire and inducing immunose
Study on lymphostromal interaction during thymic aging
Parkinson's Disease (PD) affects about 1 million individuals in the United States. In addition to the typical motor dysfunction, PD also affects cognition and vision, even in early stages of the disesse, impairing instrumental activities of dai
COGNITIVE SPEED OF PROCESSING TRAINING AMONG PERSONS WITH PARKINSON'S DISEASE
Racial and ethnic health disparities abound, with decreased quality of health care in these underserved communities. The reasons for these health inequities are complex and multi-layered. As noted by the Institute of Medicine, there are histori
Effect of implicit racial bias on recommendation of patients for total knee repla
How variant signaling strength of the B cell antigen receptor (BCR) complex is transformed into biochemical signals is not well understood. A growing body of evidence indicates that lipid rafts function as platforms for signalling through the B
A TRANSCRIPTION FACTOR WITHIN LIPID RAFTS MODULATES B CELL SIGNALING VIA THE BCR
This is a two-year award for an exploratory project whose overall goal is to understand the rules for protein-RNA recognition. There are two aims to the proposal. The first aim seeks to identify the proteins that can bind the RNA tetraloop RNA
Proteome-wide identification of RNA-binding proteins
Francisella tularensis is a gram-negative bacterium and one of the top-priority agents ('Class A') most likely to pose a potential risk to national security. Although much has been learned from a mouse model using an attenuated strain of Franci
A UNIQUE MOUSE MODEL FOR STUDYING IMMUNITY TO VIRULENT FRANCISCELLA INFECTIONS
NATIONAL HISPANIC CULTURAL CENTER FOUNDATION
To support the preservation of jobs that are threatened by declines in philantrhropic and other support during the current economic downturn.
US 95, WINNEMUCCA BLVD, FROM POTATO RD TO MELARKEY ST
TOURISM AND STATE DEVELOPMENT, SD DEPT OF
To support the preservation of jobs that are threatened by declines in philanthropic and other support during the current economic downturn, as described in your application (A09-904809) and the approved project budget.
Arts and the American Recovery & Investiment Act of 2009
Program Management Office staffing in support of managing the Ocean Observing Initiative Construction Project for the National Science Foundation. Coastal and global scale nodes development and build.
I-85 AT SR 324/GRAVEL SPRINGS RD 4.5 MI SE OF BUFORD
Provides additional funding to Area Agencies on Aging for Elderly Nutrition Congregate Meals Programs to feed seniors in need and to restore nutrition services and local food service positions  eliminated due to cost increases and funding losse
ARRA of 2009 Grant for Home Delivered Nutrition Services to reduce hunger and food insecurity and to promote the health and well-being of older individuals by assisting such individuals to gain access to nutrition by delivering meals to home-bo
ARRA of 2009 Grant for Home Delivered Nutrition Services
The Executive Office of Elder Affairs received a grant of $690,992 from the Administration on Aging to provide home delivered meals to low income elders. These meals will help elders remain healthy, independent, and active in their community.
ARRA provided funding for Congregate Nutrition Services.  Established in 1972 under the Older Americans Act, the program provides meals to older Americans in congregate facilities such as senior centers.
HEALTH & SENIOR SERVICES, NEW JERSEY DEPARTMENT OF
This Senior Nutrition Program is to provide home delivered meals for the elderly. The program was built on the Home Delivered  Meals program authorized by Title III-C-2 of the Older American's Act.  However, the Administration on Aging has limi
Dept Id.  3460020000 / Program code 43893
The Alaska Association of Conservation Districts (AACD) will coordinate invasive plant programs (IPP) throughout Alaska via coordinator positions stationed at Soil and Water Conservation Districts (SWCD).  Local Cooperative Weed Management Area
Native American Housing Block Grant, Competitive - NAHASDA eligible activity: new construction of affordable housing, and new construction, acquisition, rehabilitation including energy efficiency and conservation, and infrastructure development
100 Indian River Road Phase II and Office Building
Native American Housing Block Grant, Competitive, New Construction.  The Sunrise Acres Expansion Project’s overall purpose and expected results of this award is to improve living conditions for the elderly and near elderly population of our s
Native American Housing Block Grant, Competitive for new construction of 27 rental units with combined funding from other sources, to include development of a water storage tank reservoir, booster pump and a community center.
Native Americian Housing Block Grant, Competitive - NAHASDA - eligible ativities inluding new construction,financing, administration and planning, improvement to achieve greater enaergy efficiency, investments that leverage private sector fundi
HO-CHUNK HOUSING AND COMMUNITY DEVELOPMENT AGENCY
Native American Housing Block Grant, Competitive-This is an affordable-housing grant project with the broad scope of creating local employment in the construction industry and enhancing the availability, viability, and affordablity of low-incom
Native American Housing Block Grant - Housing and Infrastructure Development
Infrastructure to develop housing sites in Adair and Sequoyah Counties (Oklahoma) and construct 15 energy efficient houses in Sequoyah County
Native American Housing Grant- Competitive- eligible activities acquisition, new construction, rehabilitation of homes.
Wee Wun Project Construction & Newton construction & Rehabilitation
The Flathead County Fuels grant funding ($506,000) will provide wildfire fuels hazard reduction treatments to non-industrial private lands (NIPF) within Flathead County.  Target areas include the interface around communities of Marion, Whitefis
Forest Conservation, Recovery Act. Hire/retain municipal urban forestry/parks staff; contract for pruning and planting; perform canopy assessment of public and private urban forests in the Truckee Meadows; provide series of free professional de
Nevada Urban Forest Revitalization WFM-0460-21HFE
Longeleaf pine forests once covered a vast range from Texas to Virginia, but have been reduced to three percent of historical acreage due to conversion to other land uses and forest types.  Longeleaf pine forests are highly valued for their res
Georgias 6400 Forest Stewardship farms need revisiting to ascertain each landowner?s progress implementing prescribed fire and other forest management recommendations. Hiring of 20 foresters and forestry technicians will facilitate visitation t
Georgia Stewardship Revisit Prescribed Burn
Under this program, state forestry agencies in Alabama, Georgia, Florida, South Carolina, and North Carolina are putting Americans to work restoring longleaf pine forests.  Activities include restoring longleaf pine on state-owned and private l
Regional Longleaf Pine Restoration Initiative & Fuel Reduction
During the spring and summer of 2007, approximately 19,000 acres of Dixon Memorial State Forest was burned during one of the largest wildfires in the history of Georgia. The forest is located approximately 10 miles Southeast of Waycross, Georgi
Dixon Memorial State Forest Wildland Recovery & Habitat Restoration
0.69 Mi W of CSAH 12 Overpass to near TH 61 (EB and WB Lanes) Bituminous Mill and Overlay
Jct 210 to 1.1 Mi South of Big Sandy River Pavement Reclamation, Culvert Replacement (BR 6339), Turn Lanes
Replace Deck and Paint BR 73806 Under Stearns Co CR 186, 1.3 Mi E of TH 71 Replace Deck and Paint BR 73842 CR143, 11.7 Mi SW of St Cloud
Milroy to Wabasso (Rural Sections Only) Mill and Overlay
Replace BR 6419 Over Snake River at S Limits of Grasston
Near Alden, TH 22 to District 6 Boundary, Concrete Pavement Rehab and resurf Shoulders
Aerial Lift Bridge L 6116 (Lake Ave), Bridge Painting and Rehab
Lake Avenue from 3.9 Mi to 4.1 Mi NE of Jct TH 65, Replace BR 7238 and Approaches
Replace BR 5789, Cedar Ave Over Maple Creek, Precast Concrete Beam Structure and Approach Grading, Includes Rail Agreement
CSAH 12 Over the DM&E RR, Construct New Bridge
Grading, Base, Bit, Curb and Gutter, Driveway Pave, Sidewalk, Bit Trail, Storm and Sanit Sewer, Sea Pond, Watermain and Revised Signal System-S of Meadow Ln on CSAH 137 to New Alignment of 28th Aven & East of New 28th Ave Alignment, From CSAH 1
State Entry Sign Location Landscape Rehabilitation at Albert Lea, N of IA/MN Border Entry and Exit Signs
Metrowide loop detectors AT CSAH 30 (Diffley Rd/ Cedarbridge Ave. and Hills Dr/ MSAS 119 in Burnsville rebuild traffic signals
W of TH 220, Replace B 5871 over the Red River and Approach Work
WB I 494 to WB 212/5 add lane from NE loop in Eden Prairie-Interchange Modification
Reconstruct 20th St from 12th Ave to 24th Ave, Urban Grading and Surfacing in Moorhead
Oregon Department of Forestry (ODF) will provide technical field services support to the Rogue River-Siskiyou National Forest's Gold Beach and Powers Ranger Districts in administering  fuels reduction projects. Technical field services support
Fire-Risk Reduction on the Rogue River-Siskiyou National Forest-COOS BAY
Oregon Department of Forestry (ODF) will provide technical services support to the Rogue River-Siskiyou National Forest to administer fire risk reduction projects. Technical services support will include establishment of treatment areas, as wel
Fire-Risk Reduction on the Rogue River-Siskiyou National Forest-SWO
South Bay Community Services, in collaboration with partner agencies, will administer Homeless Prevention and Rapid Re-housing Program funds to assist homeless and/or at-risk individuals and families. Services to be provided include short and m
Homeless Prevention and Rapid Re-housing with the City of National City
LBL was hit by a historically severe ice storm in January 2009.  The resulting damage closed hundreds of miles of roads on he National Recreation Area.  Lbl's vital role in the $650 million Regional Tourism industry made opening the closed road
Road Clearance and Accesses into Agricultural Fields
The objective of this project is to conduct a time and motion study on mobile fast pyrolysis units to evaluate their productivity and financial feasibility for in-woods conversion of biomass into bio-oil and boichar.  The productivity, financia
Cost and Productivity analysis of In-Woods Fast Pyrolysis
Youth corps to complete conservation work projects related to fire mitigation/beetle kill projects to protect roads, trails, campgrounds and other public spaces from fire and hazard trees.
Supplemental Project Agreement between the USFS Medicine Bow-Routt National Forests and the Colorado Youth Corps Association
This project consists of 39 miles of trail maintenance in the Gila National Forest.  Work assignments will be in front-country and back-country locations.  The project will utilize up to three, eight-person crews from the Mountain Alliance of C
The purpose of this agreement is to benefit participants of the CCC by providing opportunities for job training, personal development, conservation service, and natural resource appreciation while accomplishing work on public lands under the AR
PGD2 Receptor Subtype Functions in T Cells from Asthmatics
The overall purpose is to determine the potential roles of the up-regulated genes in insecticide resistance in mosquitoes. We expect that comparison of 1) levels of resistance and the levels of gene expression and 2) the levels of silenced gene
Characterizing the role of the 22 up-regulated genes in mosquito resistance
The goal of this proposal is to delineate the viral genes that lead to severe acute respiratory syndrome (SARS) utilizing a novel rodent model of SARS. SARS infected over 8,000 persons globally with over 700 deaths. We propose to use a MHV-1 in
A GENETIC ANALYSIS OF PNEUMOTROPISM AND PNEUMOVIRULENCE  IN AN MHV-1 MODEL OF SARS
The objective of this application is to investigate the molecular mechanisms of anti-HIV activity of the LXR agonist TO-901317, a compound stimulating reverse cholesterol transport, and to test this compound in an in vivo model of HIV-1 infecti
Targeting HIV infectivity by stimulating cholesterol efflux
This project aims to define correlates of immune protection to HIV infection by assessing two poorly defined functions of HIV-specific T cells. Due to the extreme variability of HIV, the ability of T cells to cope with HIV antigenic diversity a
Role of CTL avidity in epitope variant recognition and immune control of HIV
A growing body of evidence suggests a causal relationship between the accumulation of classically activated macrophages in adipose tissue and development of insulin resistance in obesity. The molecular mechanisms regulating adipose tissue macro
Regulation of Macrophage Activation State by Intracellular Triglyceride
HIV protease is a well established target for the inhibition of viral replication and there are a handful of FDA- approved drugs that are being used to weigh down HIV protease activity. However, these drugs are exclusively targeted to the catal
Isolation and Characterization of Aptamers Targeted to Inhibit HIV Protease Matur
Sexually transmitted infections (STIs) have a huge impact on public health.  Chlamydia trachomatis is the leading cause of bacterial sexually transmitted infections globally, and is the most prevalent sexually transmitted diseases in the United
ANTI-ADHESIVE PREVENTION OF CHLAMYDIA TRACHOMATIS GENITAL TRACT INFECTION
For this project, we will construct a live vaccine that aims at preventing human salmonellosis. Salmonella enterica is a disease that causes a variety of food and water-borne illnesses, such as gastroenteritis and typhoid fever. It can infect a
Evaluation of Protein Channel-Attenuated Salmonella Vaccines
Cytomegalovirus (CMV) is a ubiquitous pathogen that causes significant morbidity and mortality in immunocompromised populations. Currently, there is no effective vaccine against CMV. Development of a vaccine, particularly for women of child-bea
Novel vaccine to CMV based on a disc virus
DESCRIPTION (provided by applicant): Hepatitis C virus (HCV) infection represents a significant global health-care problem, which is forecasted to become worse in the coming years. In the developed world, infection with HCV is responsible for 5
Targeting pDCs for the Generation of Effective Anti-HCV CD8+ T-Cell Immunity
The goal of these investigations is to elucidate the role of microparticles (MPs) as a key source of nuclear antigens in systemic lupus erythematosus (SLE) and characterize these structures as components of pathogenic immune complexes (ICs). MP
MICROPARTICLES AS A SOURCE OF NUCLEAR ANTIGENS IN SYSTEMIC LUPUS ERYTHEMATOSUS
Lyme disease is the most common vector borne disease in the United States.  Although antibiotic therapy is clinically effective in treating the symptoms of Lyme disease for patients early in the course of disease, a significant number of patien
AR CHILDRENS HOSPITAL RESEARCH INSTITUTE
There are multiple mechanisms by which bacteria elicit an inflammatory response at mucosal sites; however, a pathway mediated by neuropeptides has received little attention but may be equally as important in the induction of the inflammatory re
Role of the neurogenic inflammatory pathway in the genital tract immune response
Secretory IgA (SIgA) is an important mediator of mucosal immunity. Strategies that boost SIgA production in the airways will confer benefit to patients that have become susceptible to infections caused by airborne pathogens. Our studies point t
Arachidonic Acid Mediated Regulation of Secretory IgA Levels in the Airways
Dendritic cells (DCs) play an essential role initiating and guiding immune responses toward intestinal pathogens and non-pathogens. The intestine contains a population of DCs that are uniquely positioned at the interface of the host with the en
EPITHELIA ASSOCIATED DENDRITIC CELLS: PHENOTYPE AND FUNCTION
The immunological of the mucosal extracellular matrix, or stroma, in innate and adaptive immunity has not been critically evaluated and is poorly understood.  In view of the newly appreciated importance of the stroma in immunological cross-talk
MUCOSAL TGF BETA/IL-6 AXIS IN THE REGULATION OF T CELL FUNCTION
Influenza virus must hijack proteins present within the cells of the human mucosa in order to reproduce in infected individuals. A detailed understanding of the mucosal cell proteins required to support viral replication as well as those which
Molecular Components Specifying Mucosal Cell Sensitivity to Influenza Infection - ARRA Stimulus Funding
The tegument region of herpes viruses is located between the outer surface of the capsid and the inner surface of the envelope and is made up of approximately 20 different proteins. Recent evidence suggests that the tegument is not a static str
MODIFICATION OF A TEGUMENT PROTEIN DURING THE ASSEMBLY OF HSV-1
In addition to mediating activation of CD4 T helper cells, antigenic peptide–major histocompatibility complex (MHC) class II complexes, consisting of an alpha and beta chain) transduce signals leading to antigen presenting cell activation. Us
MHC Class II subsets in B Lymphocyte Biology
DESCRIPTION (provided by applicant): Herpes simplex virus type 1 (HSV-1) is a widespread human pathogen that causes a diverse array of diseases ranging from recurrent cold sores and genital lesions to blindness and encephalitis. The pathogenesi
The Role of VP22 in Protein Synthesis and Mrna Accumulation During HSV-1 Infectio
Non-typhoidal Salmonella, including serotype Typhimurium (STm) are food-borne bacterial pathogens that cause ~1.4 million cases of diarrheal disease annually in the United States and hundreds of millions of cases worldwide. In the intestine, ST
GENETICS OF SALMONELLA RESISTANCE TO THE INFLAMMATORY RESPONSE IN THE GUT
A hallmark of infection with positive strand RNA viruses is the impressive intracellular membrane rearrangements induced within host cells to facilitate replication of their viral genomes. This project will use a multidisciplinary approach to i
Membrane Rearrangements in Flavivirus Infected Cells
This application investigates whether increases in low-level HIV-1 residual viremia (HIV-1 RNA) set point in patients receiving antiretroviral therapy can serve as an early indicator of impending virologic failure and whether these increases in
Rise of HIV-1 Low-Level Viremia as an Early Predictor of Virologic Rebound
Although the use of highly active anti-retroviral therapy (HAART) has enhanced both the longevity and quality of life for HIV-infected individuals by controlling viral replication, financial and logistic drawbacks as well as clinical side effec
A PROPAGATING CHIMERIC PARTICLE AS A SAFE ALTERNATIVE TO LIVE-ATTENUATED VIRUS
This effort requires the development of new therapies that target the provirus residing within infected cells in a status of non-productive infection. Advances toward that goal will require a quantum leap in our knowledge and understanding of t
A New Insight into HIV-1 Latency Through a Novel in Vitro System
Retroviruses, such as HIV-1 that causes AIDS, have an RNA   genome that is reverse-transcribed into a linear viral DNA upon entering the host cell. Integration of this   viral DNA into host's chromosome is an essential step in the lifecycle of
CRYSTALLOGRAPHIC STUDIES OF RETROVIRAL INTEGRASES
Effector and regulator T cells play important roles in the homeostasis of the immune system. Recent studies showed that interleukin-17 producing effectors, known as TH-17 cells, and Foxp3+ regulator T cells, despite their apparently opposite ro
In Vivo Imaging of T-cell Differential in Inflammatory Bowel Disease
Helicobacter pylori (Hp) infects the gastric mucosa of >50% of the world's population. Infection with this gram negative bacterium results in significant gastroduodenal diseases that include chronic gastritis, ulcers and cancer. Prevalence rate
MOLECULAR PREDICTORS OF COLORECTAL CANCER RECURRENCE Lymph node involvement is one of the most important clinical features to determine when managing colorectal cancer patients. Node-negative disease is often cured by surgery alone, whereas nod
MOLECULAR PREDICTORS OF COLORECTAL CANCER RECURRENCE
Transcriptional silencing via promoter methylation of genes critically important for cell growth and differentiation plays a key role in myeloid leukemogenesis. Many genes are frequently methylated in acute myeloid leukemia (AML) including p15,
(ARRA) Maintenance therapy with decitabine for acute myeloid leukemia in first remission
Pro-inflammatory cytokines and neurobehavioral symptoms in women with breast cancer. Abstract Survivors of breast cancer report debilitating behavioral symptoms, such as fatigue and neurocognitive dysfunction, which are evident in some individu
PRO-INFLAMMATORY CYTOKINES & NEUROBEHAVIORAL SYMPTOMS IN BREAST CANCER PATIENTS
Dietary Supplement Selenium and HIF-1alpha Regulation in Cancer
The proposed work focuses on the discovery of reliable biomarkers for the early detection of liver cancer. Patients with hepatitis are particularly susceptible to the development of hepatocellular cancer, although the disease mechanisms are poo
Metabolomics-based Identification of Hepatocellular Cancer Biomarkers
Strategies to overcome resistance to common chemotherapy regimens are necessary to improve upon the currently dismal prognosis of acute myeloid leukemia (AML) patients with refractory disease or who have relapsed following initial achievement o
(ARRA) GTI-2040: An anti-sense strategy to reduce ribonucleotide reductase in AML
The selective estrogen receptor modulator tamoxifen is efficacious in the treatment and prevention of breast cancer, the most common cancer in women.  However, tamoxifen treatment causes menopausal symptoms including hot flashes.  In addition,
Chemoprevention of Tamoxifen-Induced Endometrial Cancer by Black Cohosh and Red Clover
Reactivation of Tumor Suppressor Genes in Breast Cancer by Dietary Supplements Hypermethylation-silenced tumor suppressor gene (TSG) is a hallmark of most cancers, including breast cancer and has been detected in pre-invasive lesions and/or hig
(ARRA) Reactivation of tumor suppressor genes in breast cancer by dietary supplements as DNA methylation modulators
This project will validate a novel technology that has been developed to predict which patients with esophageal or rectal cancer will respond to treatment with radiation and chemotherapy. The relevance of this technology is significant as it ma
Validation of a Prredictive Model of Clinical Response to Concurrent Radiochemotherapy
The primary goal of this application is to enhance a successful intervention that was developed to disseminate evidence-based cancer prevention strategies to workplaces. Cancer and other chronic diseases are the leading causes of mortality and
Several randomized controlled trials have demonstrated that exercise can benefit cancer patients in terms of their physical functioning and symptoms. Few studies have included patients with advanced disease, a group that is living longer with t
ONCOLOGIST-ASSISTED HOME EXERCISE PROGRAM FOR ADVANCED COLON CANCER PATIENTS
How does exercise counteract stress-induced tumor growth? Increased physical activity following the diagnosis of cancer has been demonstrated to significantly reduce cancer recurrence. Furthermore, exercise has been demonstrated to have antidep
HOW DOES EXERCISE COUNTERACT STRESS-INDUCED TUMOR GROWTH
Title: 'Manipulation of Kinase Activity by KSHV LANA' Kaposi&apos;s sarcoma associated herpesvirus (KSHV) is a herpesvirus that is associated with the blood vessel lesion Kaposi&apos;s sarcoma and the B cell malignancies primary effusion lympho
MANIPULATION OF KINASE ACTIVITY BY KSHV LANA
There are an estimated 2.2 million breast cancer survivors alive today in the US including a significant number of Asian survivors. Breast cancer is the most common cancer in Chinese women, the largest Asian population, of which 70% are immigra
CULTURAL IMPACT ON ADAPTATION BETWEEN CHINESE AND WHITE BREAST CANCER SURVIVORS
With a 5-year survival rate of less than 4% pancreatic cancer is the fourth leading cause of cancer death in the United States. Current chemotherapy and radiation therapy are largely ineffective in the treatment of this disease. Surgical treatm
Molecular mechanisms of perineural invasion in pancreatic cancer
Ovarian cancer remains a common and lethal disease. Most women diagnosed with ovarian cancer are destined to die from advanced, refractory disease, even though most also respond well to initial therapy. At least 80% of human cancers depend on a
SPRY2 predicts survival post-chemotherapy in advanced ovarian cancer
Research on therapeutic community (TC) process is critically needed. While meta-analysis has supported the effectiveness of TCs, it has also shown that effect sizes are often modest (Pearson & Lipton, 1999). It is likely that a better understan
(ARRA) Maintenance and correlates of cooperative behavior in corrections-based therapeutic communities
This research project is developing and evaluating the use of Ecological Momentary Assessment (EMA) to study the ways early adolescents may be influenced by their peers. EMA is a method of collecting self-report information in real-time and in
Ecological Momentary Assessment of Peer Affiliation, Perceptions, and Behavior
GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC.
Major activity this quarter has been directed toward development of algorithms in SAS that will permit calculation of network characteristics with interaction with other network analytic programs (such as Pajek, Ucinet).  These programs, now al
Combining Theoretical and Empirical Network Approaches to HIV Transmission
The major objective of the proposed research is to study the interaction of the brain reward system with the brain pain system and the effects of morphine on this interaction. The intracerebral implanting of two stimulating electrodes, one in a
Interactions Between the Brain Reward and Pain Systems
The primary goals of this project are to develop, refine, and pilot test an integrative smoking relapse prevention intervention for postpartum women.  Rates of postpartum smoking relapse are high (70-90%) among women who quit smoking in anticip
Postpartum Sleep Effects on Smoking Relapse
This R21 application responds to PA-07-227, which describes an urgent need for a greater understanding of the underlying neurobiological and behavioral mechanisms in the addictive effects of methamphetamine (MA) and cocaine. The use and abuse o
Nicotine Modulation of Methamphetamine's Behavioral and Neurochemical Effects
Agonists acting at the 5 opioid receptor (MOR) (e.g. morphine and its analogs) are the mainstay of pain management; however there are serious adverse effects (e.g. dependence) and social and legal issues which limit their use. Consequently ther
DELTA-KAPPA OPIOID RECEPTOR INTERACTIONS: LIGAND-DEPENDENT EFFECTS
Drug overdose is the single greatest cause of mortality among injection drug users (IDUs) in the U.S. Fatal heroin overdoses cause more than half of all deaths among IDUs, which far exceeds the proportion of deaths due to AIDS or other causes.
Evaluation of Overdose Prevention Programs for Injection Drug Users
Suicide, with its related mortality and morbidity, represents a significant and preventable loss of human life. Existing research indicates that problematic alcohol and drug use are closely linked to both fatal and non-fatal suicide attempts. G
DEVELOPING AN INTERVENTION TO ADDRESS SUICIDE RISK DURING SUBSTANCE USE DISORDER
During this two year award, we proposed to examine the role of decoy receptor expression in the ability to respond to corticosteroids during periods of acute hearing decline in patients with autoimmune inner ear disease (AIED).  AIED is difficu
A Decoy Receptor as a Novel Biomarker for Autoimmune Inner Ear Disease
Motion sickness is a debilitating condition that affects a wide range of individuals in both daily life and in pathological conditions. While it is widely seen in many clinical settings, it remains difficult to objectively evaluate and treat. R
ROLE OF CEREBRAL BLOOD FLOW IN NAUSEA AND MOTION SICKNESS
This is a translational medical research effort whose long-term goal is to develop a photochemotherapeutic system for prevention, control and/or treatment of periodontitis based on recent advances in photomedicine and nanotechnology. Biofilms t
NANOPARTICLE-BASED ANTIMICROBIAL PHOTOCHEMOTHERAPY IN BIOFILMS
The ability of the bacterium Streptococcus mutans to take up DNA from its local environment is known as genetic competence, and it is an important component of the virulence of this organism.  Existing data indicates that in the natural biofilm
Microfluidic Devices for Studying Competence in Streptococcus Mutans
This R21 proposal describes the development of three-dimensional (3-D) in vitro liver sinusoids comprised of primary hepatocytes and primary liver sinusoidal endothelial cells. These in vitro constructs will be used in detoxification studies. T
Three Dimensional In Vitro Liver Sinusoids: Design and Detoxification Studies
The growing obesity epidemic in the US has heightened the importance of its primary prevention across all ages; however, prevention efforts generally focus upon community-based intervention studies in pediatric settings or clinical intervention
Physical Activity and Diet in the Prevention of Obesity in Men and Women
DESCRIPTION (provided by applicant): The incidence and prevalence of end-stage renal disease is increasing at an alarming rate, new innovative therapies for halting the progress of chronic renal failure are urgently demanded. Overexpression of
TARGETED DELIVERY OF TGFBETA BLOCKADE TO DISEASED GLOMERULI
Although the effort to catalog the full range of epigenetic marks and assign them functional roles has been a remarkable success to date, how epigenetic states persist through replication and mitosis (epigenetic inheritance) remain as important
DYNAMICS OF EPIGENETIC MARKS ON NEWLY REPLICATED CHROMATIN
The long-term objective of this study is to understand the molecular mechanism of prostate formation and maintenance. The prostate has been the subject of intense biomedical research not only because of its key role in sexual function, but more
ARRA Investigating the Interplay Between WNT and FGF Signaling in Prostate Initiation
Diabetes is an international health concern with millions of patients worldwide. There is an unmet need to develop a biosensor technology that is a fast and convenient way to monitor blood glucose in diabetics. Thus, the particular goal of this
SELF-CLEANING SENSOR MEMBRANES TO IMPROVE GLUCOSE MONITORING IN VIVO
Osteoporosis is one of the leading health problems in the United States. Recent studies suggest that adipocytes in bone marrow and osteoblasts share the same precursor, mesenchymal stem cells (MSC). Human imaging studies [i.e., magnetic resonan
Imaging Evidence: Is there competition between marrow fat and bone?
The overall goals of this research are to improve clinical decision making in Pediatric Acute Liver Failure (PALF) by (1) developing quantitative models of prognosis and disease progression, and (2) using them to calibrate optimization models o
The Optimal Timing of Transplantation in Pediatric Acute Liver Failure
MMicroRNAs are endogenous regulatory RNAs that bind to the 3’-untranslated region (3’-UTR) of target mRNAs through imperfect complementarities and reduce the level of target protein expression.  Numerous studies have begun to reveal a criti
The ability of functional magnetic resonance imaging (fMRI) to detect brain function non-invasively with high spatial resolution opens great opportunities to advance our understanding of brain organization and function. Currently, most fMRI tec
Development of a Tissue-Specific fMRI Technique
We believe that there are a number of facts, in addition to our preliminary data; that make a study of the developmental immunotoxicity of atrazine compelling.  One, atrazine is both the most heavily used single herbicide employed in USA agricu
Precocious Immune Senescence induced by pre- & postnatal atrazine exposure
Adaptation and survival to strenuous environmental conditions are evolutionary conserved mechanisms that allow organisms to produce progeny. In general, adaptation to stress promotes the repair of protein and DNA damage and must occur rapidly.
ARRA Funded: Transitional Machinery in Stress Signaling and Tumor Suppression
Our long term goal is to study the mechanism of neurodegeneration induced by environmental neurotoxicants. This proposal is submitted to investigate gene-environment interactions in the pathogenesis of Parkinson's disease mediated through the m
GENE ENVIRONMENT INTERACTIONS IN PARKINSON'S DISEASE
The purpose of the proposed animal studies is to define the mechanistic basis for the interaction between the common genetic variant, C677T, and the availability of folate and other related B-vitamins in determining the risk of colon cancer.  U
THE MTHFR C677T SNP EXERTS BIPOLAR EFFECTS ON COLORECTAL CANCER RISK THROUGH THE WNT PATHWAY
Retinitis pigmentosa is a hereditary retinal degeneration that leads to loss of night vision, side vision, and eventually most of central vision. Cystoid macular edema (CME), a complication involving swelling of the central retina and reduction
ARRA-Modifiable Risk Factors for CME in Retinitis Pigmentosa
ROBOT-ASSISTED MOBILITY FOR INFANTS WITH SEVERE SPINA SPINA  This study will be the first to quantify the effect of intensive power wheelchair training on special needs infants with any diagnosis. Specifically, we will quantify the effect of tr
BABIES DRIVING ROBOTS: ROBOT ASSISTED INFANT MOBILITY
Cesarean section (CS) is currently used at over twice the rate recommended by the World Health Organization (CDC, 2006); use of the procedure has almost doubled in the last two decades for reasons that are as yet poorly understood. Overutilizat
A Study of the Factors Influencing Women's Decisions about Childbirth
Offspring receive differential early somatosensory stimulation through parenting and other processes, such as neonatal exposure to novelty. This early somatosensory stimulation is known to have long-term effects on the development of stress rea
Effects of Early Experience on Somatosensory Systems in Voles
Sexually transmitted infections (STI), including human immunodeficiency virus (HIV), pose significant health risks. Consistent and correct use of condoms can be a highly effective method of preventing the transmission of HIV and many STIs, yet
Children with complex chronic conditions (CCC) receive care from diverse medical, educational and social service providers through various agencies for a prolonged period of time. Coordination of care between agencies serving these children is
Understanding Coordinated Care for Children with Complex Chronic Conditions
The overall purpose of the Pine River Van Etten Lake Road Stream Crossing Improvement Project is to improve fishery habitat and reduce sedimentation in the Au Sable River Watershed by replacing 7 inadequate road/stream crossings. This project w
Pine River Van Etten Lake Watershed Road Stream Crossing Improvement Project
The Montana Conservation Corps (MCC) partnered with the USDA Forest Service, Kootenai National Forest, for this project which covers scraping and painting historic buildings on three of the forests five districts. Project work consists of repai
Painting/Scraping of Kootenai Ntl. Forest buildings elgible for the National Historic Resgistry.
Title:  ARRA Supplemental Funding for the Child Care and Development Fund (CCDF); Description:  Provide child care financial assistance to low-income working families and fund activities to improve the quality of child care.
ARRA Supplemental Funding for the Child Care and Development Fund (CCDF.  To provide child care financial assistance to low-income working families and fund activities to improve the quality of child care.
The CDDF ARRA funds will be used to provide child care financial assistance to low-income working families and und activities to improve the quality of child care
ARRA Supplemental Funding for Child Care and Develpment Fund
EIGHT NORTHERN INDIAN PUEBLOS COUNCIL INC
ARRA funds are being used to increase payment rate to provider, retain providers, decreased parental co-payments and provide increase in physical activity.
ARRA Supplemental Funding for the Child Care and Development Fund (CCDF).  Child care services are given to families by priority with very low income and children with special needs being first on the list.  All eligible Native American Indian
Over the years the Community Services Block Grant (CSBG) has provided essential help to low-income Native American families struggling economically. The CSBG Recovery Act proposal was designed ?to provide services that address employment, educa
COMMERCE, COMMUNITY & ECONOMIC DEVELOPMENT, ALASKA DEPARTMENT OF
AmeriCorps members will address community needs for health promotion and environmental action.  BIRCH (Building Initiatives for Rural Community Health) Recovery Members will engage local volunteers and youth in conducting community health needs
This grant award supports 694 AmeriCorps service positions to address community challenges created as a result of the economic crisis.  AmeriCorps members provide:  housing rehabilitation, weatherization and energy efficiency services to low in
Funded activity supports the development of workforce development training and literacy enhancement (Good Samaritan Foundation), as well as health education training and in and after-school tutoring for youth (Latin American Youth Center).
HOUSING & COMMUNITY SERVICES, OREGON DEPARTMENT OF
The American Recovery and Reinvestment Act allows 2 existing AmeriCorps programs to add AmeriCorps national service participants to address financial literacy training, home foreclosures and housing assistance, housing rehabilitation and access
The Education Awards Only Program will engage AmeriCorps members who are student teachers in developing and field testing service-learning lesson plans for K-12 classrooms. These lesson plans will then be made available for state and national r
Recovery EAP - MCSC Ed Award Project Prime
AmeriCorps members assist in a weatherization project for low income homes.  They also will serve in schools as mentors and tutors grades k-12.
HIGHER EDUCATION, CONNECTICUT BOARD OF GOVERNORS FOR
AmeriCorps members assist community-based organizations in providing employment skills training and capacity building.  All host site organizations will be identified through partnerships with Capital Workforce Partners, Hartford's regional Wor
Members assist in the expansion and quality enhancement of afterschool opportunities for youth by providing programming for youth in under-served or lowincome NH communities members will develop youth service learning activities at program site
AmeriCorps members will participate in conservation crew activities and environmental research internships.
AmeriCorps members will assist non-profit organizations to retain or expand existing services.
Using AmeriCorps Members and grants to help restart the Rhode Island economy adversely effected by the 08/09 economic downturn and financial/housing crises.
The purpose of this award is to assist VT CNCS in carrying out a national service program as authorized by the National and Community Service Act of 1990, as amended (42 U.S.C. §12501 et seq.) and in the American Recovery and Reinvestment Act
RECOVERY VT Commission on Nat'l & Community Service Formula
Our TechMission Corps program focuses on recruiting volunteers and serving at-risk youth through tutoring, literacy, mentoring, and other academic enrichment services in after-school programs.
The National Health Corps is requesting $151,154 for 12 full-time member slots under the American Recovery and Reinvestment Act of 2009 for a program with a proposed start date of August 1, 2009 and end date of July 31, 2010.  Members will be r
Big Rock Bridge replacement, construction of weirs in the stream, flow control and overflow channels, stream work, rip rap, and road approach reconstruction.
Improvements to Forest Service Roads and Bridges inside Cache County boundaries.
Recovery act road project agreement # 09-ro-11094419-059 repairs and maintenance on forest roads h30 , h31
recovery act road project / repair and maintenance on forest roads.
To remove existing aquatic organism barries and reduce sediment delivery through the installation of new timber bridges at Sites L-5 and L-15, and the intallation of a concrete box culvert at L-13.
Wingleton Road and South Mac Road stream crossing improvement
The purpose of this award is to manage and develop the VISTA campus.
The purpose of this award is to provide services for use by AmeriCorps,VISTA members and project staff working with members and to provide face-to-face training for VISTA Pre-Service Orientations (PSO), Supervisor Orientations, Leader Developme
National Providers of Conference TA and Technical Assistance
Early Head Start Quality Improvement Funds will be used to hire a part-time Family and Provider Specialist worker to reduce the case load of the existing staff assigned to the Family Child Care Option. Head Start Quality Improvement Funds will
This award provides for ARRA Cost of Living Adjustment & Quality Improvement funding. The project will allow Head Start and Early Head Start programs to make necessary improvements to the programs. Head Start and Early Head Start serve low inco
ARRA Cost of Living Adjustment & Quality Improvement
FRESNO COUNTY ECONOMIC OPPORTUNITIES COMMISSION
This award provides for ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start and Early Head Start programs.  These programs promote t
KINGS COMMUNITY ACTION ORGANIZATION, INCORPORATED
COMMUNITY ACTION PARTNERSHIP OF MADERA COUNTY, INC.
This contract awards a cost-of-living adjustment (COLA) increase of 1.84% in the amount of $57,104 for Head Start employees.  These funds must be obligated to pay for staff salaries over the 12-month period following the effective date of this
COMMUNITY ACTION PARTNERSHIP OF SAN LUIS OBISPO COUNTY, INC.
ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with provision Section 640(a)(5) of the Head Start Act640(a)(5) of the Head Start Act for the Head Start and or Early Head Start program.  Head Start promotes the
ARRA COLA/QI Head Start and Early Head Start
This award provides for ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640 (a)95) of the Head Start Act for the Head Start and Early Head Start program.  Head Start promotes the
This COLA and Quality improvement grant was extended to September 30, 2011 effective 6/21/11.  The funds are part of the quality Improvement portion of the award.   To assist the head Stat Program in promoting school readiness of low income chi
This award provides for ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640 (a)(5) of the Head Start Act for the Head Start and Early Head Start program. Head Start promotes the s
Head Start adn Early Head Start Cost of Living Allowance and Quality funding. Cost of Living Allowance was used to provide wage increase for all staff. Quality funds used for staff development and classroom improvements.
This additional award provides ARRA Cost of Living Adjustment (COLA) and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start and/or Early Head Start program. Head Start promot
Additional funding for cost-of-living adjustments and quality improvement.
COLA-MFSS will provide an additional COLA to EHS team members  QI-MFSS EHS is committed to continuously improve the quality and effectiveness of its services by improving staff qualifications and skills, and by ensuring that the physical enviro
Purpose: The purpose of Los Angeles County Office of Education, Head Start-State Preschool Division?s (LACOE) Head Start Expansion application is to expand services to 503 additional children and families in six high need communities throughout
The Head Start ARRA Expansion project serves 44 children ages 3 - 5, throughout Santa Cruz County.  The Head Start program promotes school readiness of low income and disabled children through the provision of comprehensive health, developmenta
The Head Start Expansion award increased the number of Head Start families on Kauai from 147 to 156. Eligible families were recruited and enrolled from populations and areas of Kauai traditionally underserved by Head Start. Each of the expansio
ARRA Supplemental Funding for the Child Care and Development Fund (CCDF) - Provide child care financial assistance to low-income working families and fund activities to improve the quality of child care.
ARRA - Public Health Traineeship Program A well-prepared and trained public health workforce is critical to the nations health.  South Carolina leads the nation in a number of health problems such as infant mortality, cardiovascular disease, in
Dr. Hector Arce (Yale University) will provide an unprecedented observational data set that will be used to study the evolution of the dense gas intimately involved in the star formation process. The goal of the project is to establish how infa
CAREER: Star formation and dense gas dynamics in molecular clouds
This Capital Improvement Grant is to provide mobile delivery of dental and medical services with start-up during the grant period.  Exam Tables, Medical Record files, and a Scanning software network to integrate with the Medical Charts will be
ARRA - Capital Improvement Program - Duval County
JEFFERSON COMPREHENSIVE HEALTH CENTER INC
ARRA - Capital Improvement Program - Grant #C81CS13364 was used by JCHC to rennovate the Fayette Site which included the bathrooms  and plumbing, tiling the floor, cabintry in the dental clinic and HVAC system. It is amazing the differences tha
The Children’s Hospital & Research Center Oakland has been working towards a implementing a certified electronic health record.  Our Health Information Management team lead by Donald Livsey has assembled regularly scheduled meetings.  The pro
Consistency and Upgrade of Hardware and Software Infrastructure in Preparation for HER
SERVICIO DE SALUD PRIMARIOS DE BARCELONETA, INC.
ARRA-Capital Improvement Program (CIP)- Improve the Center's facilities to provide quality health care in a safe environment for patients, employees and visitors. GOALS: 1)Provide the building with a water reserve tank for emergencies. (We boug
SOUTH COUNTY COMMUNITY HEALTH CENTER, INC.
This award is in support of Ravenswood Family Health Center's Center for Health Promotion project.  CIP funds will support alterations and renovations and related equipment, furnishings and fixtures for a 4,000 sf facility that will house our c
CENTER FOR HEALTH PROMOTION ALTERATION AND RENOVATION
This Capital Improvement Grant will support information technology enhancements and furniture for dental and medical services -- hardware and software to support primary care, dental, and mental health services.  Furniture and equipment to supp
ARRA - Capital Improvement Program - Citrus County
LINCOLN COMMUNITY HEALTH CENTER, INCORPORATED
The Capital Improvement Program Grant (CIP) allows funding for renovation of our current physical plant to create 15 new exam rooms for adult medicine and pediatric patients. By increasing the overall number of exam rooms by 48%, from 31 to 46,
ARRA - Capital Improvement Program.  The CIP funds will help support CHCRR's vision and goals to increase primary care access to meet current and projected patient demands, expand availability and access to reduced 340B pharmaceuticals to all C
SeMRHI was awarded the Capital Improvement Program to make necessary renovations and repairs for 8 project sites.  Project 1 is renovation and repair of the Lumberton Family Health Center which will lead to improved access to care and increasin
SOUTHWEST LOUISIANA PRIMARY HEALTH CARE CENTER INC
Funds were awarded initially on June 29, 2009, and reissued on October 8, 2010 for the American Recovery and Reinvestment Act.   SWLPHC had begun preparations for two much needed projects;  a Mental Health Wing at the Opelousas site in St. Land
The grant name is Capital Improvement (CIP); which was geared towards the construction of a new building project.  More specifically, this project was to build a new dental, behavioral health, and pediatrics facility, adjacent to our original m
The title of the project is ARRA - Capital Improvement Program. This capital grant is for a space addition for the clinic and an electronic health record upgrade. The goal of the space expansion component is to build additional examination room
ARRA - Capital Improvement Program - Primary Health Services Center (PHSC) was awarded $610,920 to enhance the health center's effectiveness and improve patient outcomes by purchasing new dental equipment to increase service access for the vuln
The major portion of this award is to expand and modernize the Health Center's dental services suite.  The existing suite was built 17 years ago in an 1800's farmhouse.  It consists of 2 dental operatories and 1 dental hygiene area, and current
FRANKLIN C FETTER FAMILY HEALTH CENTER INC
Franklin C. Fetter has been a primary health care delivery system in the Berkeley, Charleston, Colleton and Dorchester Counties for more than 41 years. The CIP will enable the organization to continue to provide optimal quality health care to a
The projects that are proposed will materially increase the effectiveness, efficiency, quality of care and patient outcomes in the following ways: 1) The renovation of the Day Center will give us greater capacity to provide our current services
Lincoln Phase II:  This project provides for the demolition of the old building except for 2880 square feet, and the construction of a new administration building on the same site which will connect with the building that houses the clinical se
With the passage of the American Recovery and Reinvestment Act (ARRA), the Piedmont Health Services Inc. (PHS) Board and senior management team began an immediate review of capital needs.  The projects contained in this Capital Improvement Prog
ARRA- Capital Improvement Program to expand patient access and improve patient flow at CHCI's oldest FQHC- Mary Mahoney Memorial Health Center.  CHCI is remodeling 9,500 sq. ft. of existing space to offer more provider offices while 5,700 sq. f
The CIP funding will upgrade the existing certified electronic health records and patient practice management system to further improve the center?s effectiveness, efficiencies, quality of care and patient outcomes. In addition, needed diagnost
ARRA Capital Improvement Program Grant.  The purpose of the grant for Hardeman County Community Health Center was to build a new clinic faciity at a new site in Henderson (Chester County), Tennessee to replace a clinic we were leasing.  The goa
Autism spectrum disorders (ASD) are marked by significant impairments in social functioning and social cognition; although these symptoms are core features of ASD-and perhaps the most debilitating-there has been little headway in the developmen
THE EFFECTS OF OXYTOCIN ON COMPLEX SOCIAL COGNITION IN AUTISM SPECTRUM DISORDERS
This project is in response to the Recovery Act Limited Competition: Research to Address the Heterogeneity in Autism Spectrum Disorders (RFA-MH-09-172). The proposed project will determine the applicability, reliability, and validity of the new
COMPUTER ADAPTIVE TESTING OF ADAPTIVE BEHAVIOR OF CHILDREN AND YOUTH WITH AUTISM
Autism spectrum disorders (ASDs) are common, debilitating disorders affecting social interaction, communication, and repetitive behaviors. Recent genetic findings have identified mutations in synaptic cell adhesion genes and genes encoding thei
Novel Genetic Animal Models of Autism-ARRA Stimulus Autism Res
Asthma has long been recognized as having a significant psychosocial component. Considerable evidence exists that psychosocial factors, such as anxiety, depression, and inhibited temperament, are associated with asthma. While many studies have
Temperament as a Risk Factor in a Monkey Model of Asthma Susceptibility
SAINT VINCENTS CATHOLIC MEDICAL CENTERS OF NEW YORK
In patients with chronic obstructive pulmonary disease (COPD), which is characterized by bacterial colonization of the airways, co-infection with respiratory viruses further impairs host defenses, leading to bacterial overgrowth and infection,
CO-INFECTIONS OF RHINOVIRUS AND BACTERIA IN CHRONIC LUNG DISORDERS
Acting on multiple tissue types, adiponectin (Adipo) exerts insulin-sensitizing and cardiovascular protective effects. The physiological and/or clinical implications are that the plasma level of Adipo is negatively related to adiposity, insulin
GST alleles and oxidant pollutants in the pathogenesis of asthma - ARRA Description:  Glutathion S-transferases (GSTs) are a superfamily of enzymes responsible for both the detoxification of a spectrum of xenobiotics and the response of cells t
GST alleles and oxidant pollutants in the pathogenesis of asthma - ARRA
The goal of this project is the prototype development and evaluation of a wireless laboratory animal monitoring system (WLAMS) for the improvement of animal welfare and the direct and real-time monitoring of disease status. The system will cons
Wireless Real-Time Monitoring of Research Animals
Multiple pathway models of attention deficit hyperactivity disorder (ADHD) Project Summary/Abstract The goal of this grant is to examine brain differences during executive functioning and reward processing among children with attention deficit
Multiple Pathway Models of Attention Deficit Hyperactivity Disorder (ADHD)
Brain-derived neurotrophic factor (BDNF) plays a fundamental role in determining the plasticity and functional architecture of neurons in the adult brain. A frequent, non-conservative polymorphism in the human BDNF gene has been recently identi
INCREASED VULNERABILITY OF BDNF DEFICIENT MICE TO MILD STRESS
Epigenetic regulation of microRNAs in neurogenesis Histone deacetylase (HDAC) inhibitors such as valproate (VPA) are commonly used to treat epilepsy. One me- chanism of their efficacy may result from epigenetic effects on differentiation of neu
Epigenetic Regulation of MicroRNAs in Neurogenesis
Efforts to improve adherence to highly active antiretroviral therapy (HAART) regimens are critical for improving clinical outcomes in HIV-infected patients and reducing costly utilization of hospitalizations, emergency department and urgent car
Optimizing Multipdisciplinary HIV Care Team for Maximal HAART Adherence
ARRA [F-18]Mefway PET to measure 5-HT1A receptors in gene x environment interactions
The overall study objective is to develop a culturally targeted patient navigation training curriculum aimed at increasing breast, cervical and colorectal cancer screening behaviors in lesbian, gay, bisexual and transgendered (LGBT) persons. We
Development of a Culturally Targeted Patient Navigation Curriculum for LGBT Adults
Improving Self Management and Outcomes in Heart Failure Patients with Diabetes  Abstract This proposal addresses the problems of poor patient outcomes and high readmission rates in patients with concomitant heart failure (HF) and diabetes melli
IMPROVING SELF MANAGEMENT AND OUTCOMES IN HEART FAILURE PATIENTS WITH DIABETES
Parkinson's disease (PD) is a progressive disease that usually affects the motor system, but it is also associated with a non-motor symptom complex that contributes significantly to morbidity and institutionalization, more than quadrupling the
Dopaminergic Modulation of Cognitive Aspects Of Skill Acquisition in PD
The principal purpose of this project is to discover the biological changes that take place as a result of learning.  We plan to characterize the changes that take place in identified neurons in the deep cerebellar nuclei as a function of class
The funding obtained under the ARRA is for conducting research within the broad area of Alzheimer?s disease (AD) pathogenesis. Although several AD-linked genetic mutations have been identified that directly cause the disease (due to an accumula
GABAergic interneurons, born in remote germinative zones in the ventral forebrain (telencephalon) migrate tangentially into the cortex to adopt their specific positions. The cell types and molecular cues that regulate this migration remain to b
Embryonic Vascular Networks and GABA Neuron Migration
A central question in neurodegenerative diseases is how specific populations of neurons undergo cell death. Selective degeneration of motor neurons occurs in the setting of diverse insults including RNA viruses such as HIV and West Nile, and in
INNATE IMMUNE MECHANISMS OF MOTOR NEURON INJURY
An arteriovenous malformation (AVM) is a vascular malformation in the brain with direct connections between arteries and veins such that blood bypasses brain tissue. A patient with an AVM may not be aware of it until the AVM causes hemorrhage i
EVALUATION OF VASCULAR MALFORMATION HEMODYNAMICS USING ASL PERFUSION MRI
Clinical evidence suggests a strong link between Alzheimer's disease (AD) and cerebral microvascular dysfunction, but it remains unclear whether they contribute independently to dementia, or if AD pathology triggers microvascular disease, or vi
ROLE OF CORTICAL MICROVASCULAR LESIONS IN AMYLOID-BETA ACCUMULATION
The rat respiratory system is an excellent model for experimental design in addressing respiratory-related issues that arise from injury. The C2 hemisection is a reliable and simple model employed in SCI research on the respiratory system. In t
MOLECULAR MECHANISMS MEDIATING RECOVERY AFTER SCI-INDUCED HEMIDIAPHRAGMATIC
This study is part of an ongoing collaborative effort between researchers at the University of Texas Health Science Center at San Antonio (UTHSCSA), Research Imaging Center (RIC), and the Southwest National Primate Research Center (SNPRC) at th
MULTIMODAL EVALUATION OF NETWORKS UNDERLYING PHOTOSENSITIVE EPILEPSY IN BABOONS
The goal of this research is to elucidate the physiological and molecular responses that occur in response to persistent mitochondrial DNA (mtDNA) damage. Mitochondrial DNA integrity is critical for human health, and mtDNA is more sensitive tha
MOLECULAR & PHYSIOLOGICAL RESPONSES TO PERSISTANT MITOCHONDRIAL DNA DAMAGE
Traumatic brain injury (TBI) is a global health problem that is financially crippling for many families because of both specialized care and lost financial income. TBI involves at least two separate injury cascades that lead to neuronal and cog
Glioma is the most frequent primary intracranial neoplasm in adults and are invariably fatal. Malignant gliomas account for approximately one-third of all primary brain tumors in adults or 18400 new cases in the United States annually. Despite
MR Imaging of pHe and Chemotherapeutic Response in a Rat Glioma.
Chronic pathological pain and certain epileptic syndromes are neuropsychiatric disorders that share an increased female prevalence and refractoriness to treatment. The latter feature is considered to be linked to pathologically increased neuron
SEX-SPECIFIC GENE REGULATION OF NEURONAL CHLORIDE CO-TRANSPORTER, Kcc2
Stroke is the major neurological illness and recombinant tissue type plasminogen activator (rtPA) is the only approved treatment. Use of rtPA is limited to three hours after stroke because of the risk of intracerebral hemorrhage. Toxicity of rt
Matrix Metalloproteinase Inhibitors in Stroke
Multiple Sclerosis (MS) is the prototypical CNS demyelinating disease, and though remyelination often occurs in the early stages of the disease, it eventually fails in later stages, contributing to progressive functional decline. All approved m
ROLE OF TELOMERASE IN MYELINATION AND REMYELINATION
Title:  High Content Screens of Neuronal Development for Autism Research.  Disrupted neural development is thought to underlie autism and related disorders such as Rett syndrome, but the mechanisms are unknown and possibly highly diverse. This
HIGH CONTENT SCREENS OF NEURONAL DEVELOPMENT FOR AUTISM RESEARCH
Conventional 2D-PAGE is cumbersome, slow and difficult to automate. Although, multidimensional, high performance capillary chromatography, electrophoresis and electrochromatography are robust and fully automatable, they are bottlenecked by thei
MULTIDIMENSIONAL ELECTROFOCUSING ON GRADIENT MONOLITHS
Characteristics of the built environment can create/sustain health disparities, hence tackling them requires interventions to address macro-level factors that influence health. By addressing the causes of health disparites among Latino children
Nuestro Futuro Saludable: The JP Partnership fro Healthy Caribbean Latino Youth
Improvement in health for populations around the globe has become a leading international priority. As the world becomes progressively more interconnected, it is apparent that major global health burdens facing our international community will
ARRA - UNM Framework Program in Global Health
DESCRIPTION (provided by applicant): Literature and clinical research suggest that improvements in communicative initiations are associated with widespread improvements in communication and in related core symptoms of autism (communicative, soc
Child-Initiated Communicative Interactions and Autism Intervention
DESCRIPTION (provided by applicant): Autism spectrum disorders (ASD) affect approximately 1 out of 150 children and adolescents in the United States, making them one of the most common neurobiological conditions. Comorbid anxiety disorders affe
2/3 CBT FOR ANXIETY DISORDERS IN AUTISM: ADAPTING TREATMENT FOR ADOLESCENTS
Elderly persons who have suffered a disabling medical event, such as a hip fracture, are likely to develop depression. Late-life depression (LLD) adversely affects acute medical rehabilitation, increasing the risk for persistent depression and
ENHANCED ACUTE MEDICAL REHABILITATION FOR LATE-LIFE DEPRESSION AFTER HIP FRACTURE
The granuloma developed in the host in response to Mycobacterium tuberculosis (Mtb) is a protective structure that curtails the spread of the pathogen and controls reactivation of latent/persistent Mtb.  Despite this knowledge, the molecular pa
We propose to develop and apply a comprehensive set of experimental and computational methods for revealing the genetic basis of antibiotic tolerance in Escherichia coli. At the core of our approach is a microarray-based genetic footprinting te
COMPREHENSIVE GENETIC CHARACTERIZATION OF ANTIBIOTIC RESISTANCE
Lyme disease is the most common vector-borne disease in the U.S. and and an important public health problem whose incidence continues to increase. In our preliminary work, we have shown that Borrelia burgdorferi, the causative agent of Lyme dis
Role of Borreila Integrin binding proteins in Lyme arthritis
Inflammatory destruction of target organs in autoimmune diseases, including rheumatoid arthritis (RA), begins with the emigration of effector cells from the microcirculation.  Suppression of inflammatory leukocyte extravsation could provide pro
Cyclophilin-CD147 interaction in autoimmune arthritis
Shigella, a major etiologic agent of diarrhea, dystentry, and mortality worldwide, causes disease by invading and disseminating through the colonic mucosa.  Shigella sp. CDC/NIAID Category B priority pathogens.  After inducing their own entry i
Molecular Signaling in Shigella Dissemination
Most bacterial viruses (?bacteriophages? or just ?phage?) are highly efficient in their ability to infect their often very specific bacterial hosts. In general, only one or a few viral particles are necessary to successfully infect one bacteriu
Structural Studies of Bacteriophage T4 and Their Potential Medical Applications
Francisella tularensis is an extremely virulent Gram negative bacterial pathogen capable of causing rapidly progressing lethal infections in literally hundreds of diverse animal species, including humans. Transmission from infected animals to h
National surveillance of emerging MDR in pediatric Enterobacteriaceae infections  The growing problem of antimicrobial resistance is well recognized. Infections with multi-drug resistant organisms are challenging to treat, and are associated wi
National surveillance of emerging MDR in pediatric Enterobacteriaceae infections
The purpose of this proposal is to determine the mechanisms for the loss of B cell tolerance to phospholipids and for tissue damage by anti-phospholipid  antibodies in NZW/BXSB F1 (W/B) mice. W/B mice develop both proliferative glomerulonephrit
Regulation of the anti-phospolipid response in SLE
Despite decades of research, the immunological correlates of protection against HIV-1 infection in humans or SIV infection in nonhuman primates remain poorly understood. In contrast, studies on Friend retrovirus (FV)infection in mice highlighte
Apobec3 and the Neutralizing Antibody Response Against Pathogenic Retroviruses
Escape of Mycobacterium tuberculosis from the macrophage is regulated by eicosano
The purpose of this study is to evaluate ultra-short echo (UTE) imaging as a buiomatker of meniscal integrity by biomechanical and histological measures in an ovine model of meniscal repair: site-specific meniscal T2* values will be correlated
Evaluation of an MRI Biomarker For Meniscal Repair
This application addresses broad Challenge Area 06 – Enabling Technologies – and specific Challenge Topic, 06-DA-104: Development of new technologies to change patient and provider behaviors to improve adherence.   Since the advent of highl
Test of a Web-Based Program to Improve Adherence to HIV/AIDS Medications
Enormous unmet needs for alcohol prevention and treatment exist among individuals arrested for driving under the influence (DUI), as nearly one third recidivate and have a subsequent arrest. The DUI arrest represents a critical opportunity for
USING TECHNOLOGY TO DELIVER BRIEF INTERVENTIONS IN DUI PROGRAMS
This application addresses broad Challenge Area (05) Comparative Effectiveness Research and specific Challenge Topics, 05-AA-101: Innovative Analysis of Existing Clinical Datasets and 05-AA-102: Adaptive Designs and Person-Centered Data Analysi
NEW APPROACHES TO MEDIATION ANALYSIS USING CAUSAL INFERENCE METHODS
Recent studies indicate that neuroimmune factors are important signaling molecules in the brain and contribute to both normal brain function and cognitive dysfunction associated with a variety of disorders including alcoholism. Our knowledge ab
Surface Enhanced Transmission Mode Desorption Electrospray Ionization for Metabolite Profiling from Dried Blood Spots This application addresses broad Challenge Area (03) Biomarker Discovery and Validation, and specific Challenge Topics, 03-AG-
Surface Enhanced TMDESI Mass Spectrometry for Metabolomics from Dried Blood Spots
Effective drugs, such as aspirin, beta-blockers, statins, and ace-inhibitors, are a cornerstone in the prevention and treatment of heart disease, yet over half of appropriate patients do not receive them. The cost of chronic drug therapy is a s
EFFECT OF PRESCRIPTION DRUG BENEFITS ON CARDIOVASCULAR OUTCOMES IN THE ELDERLY
Effectiveness of Feeding Tubes Among Persons with Advanced Cognitive Impairment This application addresses broad challenge area (05) Comparative Effectiveness Research, Challenge Topic 05-AG-101: Data Infrastructure for Post-Marketing Comparati
EFFECTIVENESS OF FEEDING TUBES AMONG PERSON WITH ADVANCED COGNITIVE IMPAIRMENT
RNA cleavage is a fundamental and ancient host response for controlling viral infections in both plants and animals. In higher vertebrates, including humans, RNA cleavage as a means of controlling viruses is mediated by the type I interferons (
AMPLIFICATION OF ANTIVIRAL INNATE IMMUNITY BY SUPPRESSOR OF VIRUS RNA (svRNA)
This challenge project is based on (a) our pioneering work on IRGM as an autophagy factor 1, and (b) the genetic linkage recognition 2 of the role of autophagy and IRGM in Crohn's disease. The main objective is two-fold: (I) to delineate the ro
This application addresses broad Challenge Area (15) Translational Science and specific Challenge Topic, 15-AI-102 Develop diagnostics and drugs for multiple or extensively drug-resistant tuberculosis (MDR/XDR TB). We will develop a rapid and h
AFB Smears for drug Resistance Detection and surveillance in MTb
DESCRIPTION (provided by applicant): Improved interfaces for prostheses to improve rehabilitation Attaching exo-prostheses directly to bone-anchored, osseointegrated implants that pass percutaneously through the skin is being considered as an a
MOBILE POROUS SUBDERMAL BARRIER TO MAINTAIN THE SKIN SEAL OF PERCUTANEOUS DEVICES
This application addresses broad Challenge Area (08) Genomics and specific Challenge Topic, 08-AR-101: Genotyping of Existing Cohorts in Rheumatic, Skin, and Musculoskeletal Diseases. These studies will utilize existing clinical cohorts to crea
GENETICS OF JUVENILE IDIOPATHIC ARTHRITIS
In response to the need for treatments appropriate for adolescent smokers in rural Appalachia, this research (utilizing a two-group randomized-control design, n=35 per group) will evaluate the effectiveness and efficacy of a new and innovative
A web-based Intervention with Adolescent Smokers of Appalachian Ohio
This integrated laboratory and clinical proposal seeks to validate molecular determinants affecting [18F]-FLT PET imaging as a biomarker of response to targeted therapeutics in colorectal cancer (CRC). The introduction of molecularly targeted t
Molecular Determinants Affecting FLT-PET in Colorectal Cancer
This application addresses broad challenge area (10) Information Technology for Processing Health Care Data for Research' and specific challenge topic 10-CA-102 Predictive Mathematical Models of Normal and Cancer Processes. This proposal will
PREDICTIVE MATHEMATICAL MODELS FOR RATIONAL DESIGN OF CHEMOIMMUNOTHERAPY OF LEUKE
Genome-wide Determinants of Prognosis for Early-Onset Breast Cancer This application addresses broad Challenge Area (08) Genomics and specific Challenge Topic, 08-CA-101: Augmenting Genome-Wide Association Studies Prognosis for breast cancer is
GENOMEWIDE DETERMINANTS OF PROGNOSIS AND TREATMENT OF EARLY-ONSET BREAST CANCER
Acute lymphoblastic leukemia (ALL) is one of the leading causes of cancer related death in the adolescent and young adult (AYA) population. Relative to younger children with ALL, the overall outcomes in AYA ALL are significantly poorer. Whether
GENOMIC ANALYSIS OF ADOLESCENT AND YOUNG ADULT ACUTE LYMPHOBLASTIC LEUKEMIA
Patient navigation (PN) is a community-centered approach that can potentially reduce health disparities by enhancing access to care at an earlier stage of the disease continuum for underserved populations, such as racial/ethnic minorities or in
A COMPREHENSIVE MODEL TO ASSESS THE COST-EFFECTIVENESS OF PATIENT NAVIGATION
This application addresses broad Challenge Area (05) Comparative Effectiveness Research and specific Challenge Topic, 05-CA-104*: Comparative Effectiveness Research on Cancer Treatment. We propose to address two distinct but related challenges:
Comparative effectiveness research using NCCN data
Adjuvant endocrine therapy improves outcomes for estrogen receptor positive (ER+) early stage breast cancer.  Recently aromatase inhibitors (AIs) have been shown to provide incremental benefit over tamoxifen.  In neoadjuvant endocrine therapy s
MEASURES OF ENDOCRINE SENSITIVITY IN EARLY BREAST CANCER
The proposed project advances efficient and effective health research, and ultimately the quality of health care provided to the public, by removing unnecessary barriers to that research created by inappropriate and inconsistent privacy regulat
The relationship between the position of gene loci in the nucleus and cell physiology has emerged as an important facet of cell biology. Chromosomal translocations occur when double stranded breaks in DNA are repaired by incorrectly fusing one
Live cell imaging of lgH and c-Myc gene loci and the role of nuclear organization
Advanced, metastatic prostate cancer that progresses following hormone (androgen) suppression, has no known cure, and contributes to substantial morbidity and mortality. This proposal aims to categorize advanced castration-resistant prostate ca
Mechanism-based Classification and Targeting of Castration-Resistant Prostate Cancer
This application addresses broad Challenge Area (05): Comparative Effectiveness Research and specific Challenge Topic 05-DA-102: Treatment of Substance Abuse and Related Health Consequences Using Web-Based Technologies. Web-based videoconferenc
IMPROVING SUBSTANCE ABUSE COUNSELING ADHERENCE USING WEB-BASED VIDEOCONFERENCING
This application addresses broad Challenge Area (04) Clinical Research and Specific Challenge Topic, 04-DA-102: A New Look at Longitudinal Data. Despite decades of research on the etiology, prevention and treatment of substance use disorders, s
EMERGENCE OF ADOLESCENT SUBSTANCE USE PROBLEMS FROM THE EXTERNALIZING SPECTRUM
The ultimate goal of this research is to fundamentally change the ways in which behavioral interventions are delivered. We propose an innovative mobile Enabling Technology-iHeal-that recognizes stressors that threaten a patients recovery and th
A mobile Enabling Technology to promote adherence to behavioral therapy
This application addresses broad Challenge Area (03) Biomarker Discovery and Validation, and Specific Challenge topic 03-DA-101, Biomarkers for Pain. The challenge Pain is a central health problem that affects quality of life and productivity f
Neuroimaging-based biomarkers for two components of pain
The increasing recognition of the importance of epigenetic regulation of gene expression for numerous areas of biology and medicine has led to a growing interest in this field. Despite many advances, our understanding of the molecular aspects i
Mechanism-Based Small Molecule Epigenetic Modulators: Targeting Specific HDACs
It is projected that by 2030 there will be over 40 million adults and over 2 million children with hearing loss in the United States. The average reduction in earning potential for individuals with hearing aids is estimated to be $11,500 per y
ARRA Contrast Enhancement to Improve Speech Recognition with Hearing Devices
Proper salivary gland function is critical for oral health. Radiation therapy for head and neck cancer often causes significant secondary side effects that impact normal salivary gland function, most commonly xerostomia. The ensuing salivary gl
AUTOPHAGY & FUNCTIONAL RESTORATION OF IRRADIATED SALIVARY GLANDS
This research focuses on combining foundational and lightweight formal methods to verify the safety, security, and dependability of large-scale software systems. Foundational approaches (to formal methods) emphasize expressiveness and generalit
TC: Large Collaborative Research: Combining Foundational and Lightweight Formal Methods to Build Certifiably Dependable Software
ARRA - Nurse Faculty Loan Program provides support to students to cover tuition, fees, books and other reasonable education expenses. Eligible students must be enrolled in an eligible Master's program to prepare for a career in nursing.
Nurse Faculty Loan Program is used for making NFLP loans to eligible students and for the costs associated with collection of these loans. Goals-School offers full support requested to cover tuition and fees. Importance-Borrowers must complete
The Electronic Oral Health Record (EOHR) Project will allow expansion and dissemination of Health Choice Network's successful, multi-market, sustainable business model for adoption of EOHR into community health centers (CHCs)in West Virginia, R
ARRA - Health Information Technology Implementation
ARRA State Loan Repayment Program (SLRP) funds assist States in addressing the health professional shortages that cause disparities in access to health care. The program is an incentive used by underserved communities to recruit and retain heal
STATEWIDE HEALTH PLANNING AND DEVELOPMENT, CALIFORNIA OFFICE OF
ARRA - State Loan Repayment Program.  The purpose of this award is to assist with the repayment of educational loans for primary healthcare professionals who provide healthcare services in federally designated Health Professional Shortage Areas
New Access Piont Grant for Mountain Top Area Medical Association
Due to the recent increase in demand for services from the area's growing uninsured, Boston Mountain Rural Health Center (BMRHC) has hired a family practice physician and nurse health educator.  The educator will travel to all clinics, providin
Access to Health addresses the need for health services for the uninsured through three strategies:  community outreach, community information and awareness activities, and a mobile dental screening program.  The mobile health screening project
ARRA- Increased Demand for Services (IDS)
Junta del Centro Comunal Dr. Jose S. Belaval Inc. received the Notice of Grant Award for Increase Demand Services funds by the end of March 2009. Extensive planning was done prior to the submission of the proposal giving priority to our communi
To support approved application for funds to support Increased Demand for Services. The American Recovery and Reinvestment Act(ARRA) of 2009 included funds for increased services at existing sites, and for spikes in demand to serve uninsured po
This Increased Demand For Services grant sets out to offer additional operational hours at our clinics to increase access for residents unable to seek treatment during a traditional work week.  This grants supports staff salaries for Saturday m
The Increased Demand for Services grant will expire at the end of March 2011. IDS dollars have allowed the North Port Health Center to add 12 hours per week of Advanced Nurse Practitioner primary care time plus the time of her support staff equ
ARRA - Increase Services to Health Centers - Sarasota County
The purpose of the Increase Demand for Services (IDS) grant is to provide additional primary health care services for Mountain People's Health Councils, Inc. (MPHC) patients.  The goal of the project is to expand primary care services to patien
CUSTER COUNTY COMMUNITY HEALTH CENTER, INC.
Funding for the hiring of a Family Practice Physician and a Family Nurse Practitioner to increase the number of women, children, and the uninsured that we serve. We continue to search for a Physician provider.  We have engaged several recruiter
Increase Demand for Services Funding- to hire and retain providers to provide health care services to respond to an increased demand on capacity. Grant Name: ARRA - Increase Services to Health Services. Purpose: to retain and hire providers to
ARRA - Increased Demand for Services (IDS)  Rural Health Medical Program, Inc. (RHMP) will address the need for health services in the community and target population by providing enough staff to assure that quality services and an increase in
ARRA - Increased Demand for Services (IDS).  This grant provided funds to increase primary care staffing to accomodate a significant increase in unemployed and uninsured people to our community health center in Wautoma, Wisconsin.  The goals we
IDS Funds will be used to expand both medical and oral health services.  We will add a Physician Assistant, two dentists, two dental assistants, and a dental office assistant.  The added medical and dental staff wil be directly responsive to th
The intent of award is to provide access to those unable to access services during regular working hours with a focus on seasonal farm workers/Latinos and also working people and those dependent on transportation not available during working ho
ARRA - INCREASE SERVICE TO HEALTH CENTERS
Syracuse Community Health Center will enhance its patient care delivery system by increasing our provider staffing and expanding the hours of coverage available.  This will enable the organization to help meet the increasing demand for services
ARRA-INCREASE DEMAND FOR SERVICE - SYRACUSE COMMUNITY HEALTH CENTER, INC. LOCATED IN ONONDAGA COUNTY AND IN THE CITY OF SYRACUSE, NY
The Increased Demand for Services (IDS) funds were utilized to increase health center staffing by 2.80 FTE and extend hours of operation to include early morning hours Monday thru Friday, 8:00 am to 9:00 am and evening hours Monday and Tuesday,
ARRA - Increase Services to Health Centers:  WMCHC will implement the IDS project by recruiting a Psychiatrist and Family Practice Physician. The addition of a full-time Psychiatrist to the Behavioral Health Center in Honesdale will meet the 1.
Health care environment issues that impact service delivery in the Aiken County community health center setting includes extreme budget cuts in the state health care system that have resulted in health care provider shortages, particularly in r
SAMUEL U RODGERS COMMUNITY HEALTH CENTER, INC
The Health Center hired two interpreters that are certified in medical terminology,and understands the culture of or patients. Hired call center staff who are bilingual and bicultural and are able to reduce barriers to making appointments.  Hir
Funding from the ARRA - Increase Services to Health Centers grant will allow for much needed staffing support for our sites in Newton, Plainfield and Phillipsburg, New Jersey.  Specifically, the funding will allow for the expansion of medical s
Project Description Mental and behavioral services are vital for children and families living in homeless and transitional situations.  While our services target the child, we never forget to consider the parent/caregivers as well as others in
To assist Community Health Centers with an expected increased demand for services based on the current economic environment.
Increased outreach-based health care services to individuals experiencing homelessness
This report is for the Westside Park Elementary School-Based Health Center (WSP), Center Program Recovery Act, Increased Demand for Services (IDS) located in the city of Adelanto, California.  This service site is in a rural desert community on
ARRA--Increased Services to Health Centers
In response to the critical needs in many health care professions, there has been a rapid increase in health care education and training programs at UAA over the past decade.  Several excellent programs have developed to lead students into heal
Educating a Health Care Research Workforce in Alaska to Reduce Health Disparities
We propose to study the molecular details of ethanol action at extrasynaptic GABA(A) receptors, a subset of inhibitory neurotransmitter receptors implicated as key targets in both acute alcohol action and in adaptation to chronic alcohol exposu
ETHANOL SENSITIVITY IN DELTA SUBUNIT-CONTAINING GABA (A) RECEPTORS
The treatment of P. aeruginosa infections is often difficult: these bacteria are highly resistant to most antibiotics and grow as biofilms that cannot be effectively eradicated by antimicrobials or the human immune response. Completion of these
Regulation of Motility and Organelle Assembly at the Psudomonas Aeruginosa Pole
Nucleotide-binding oligomerization domain 2 (NOD2) is a monocyte-restricted member of a protein family critically involved in the activation of NF-?B in response to certain intracellular microbial infection. Dysfunctional mutations in the NOD2
Weill Medical College of Cornell University
CD4+CD25+ regulatory T (Treg) cells express the forkhead transcription factor Foxp3 and are essential for the maintenance of dominant immunological tolerance to the ‘extended self’, which includes self proteins and the commensal microbial f
Regulatory T Cell Selection and Specificity
To maintain tissue homeostasis and normal functions, damaged cells need to be replaced or repaired. In mammals, such process requires extensive cell proliferation. A consequence of this massive proliferation is the accumulation of mutations, so
Genetic Pathways of Replicative Senescence and its Function in Tumorigenesis
Title: SYSTEMS APPROACH TO SJOGREN'S SYNDROME PATHOGENESIS (SASSP) This proposal aims to test the hypothesis that the salivary gland pathologies in primary Sjögren's syndrome (pSS) are mediated by aberrant activities of key intracellular/inter
SYSTEMS APPROACH TO SJOGREN'S SYNDROME PATHOGENESIS (SASSP)
) in all parts of the intestinal tract. Our project investigates the specification of intestinal stem cells during development in Drosophila melanogaster. The key idea is that the genetic program that specifies stem cells during development wil
GENETIC CONTROL OF INTESTINAL STEM CELLS IN DROSOPHILA HINDGUT
The broad goal of this work is to use the C. elegans model system to understand the genetic and molecular mechanisms underlying the developmental regulation of microRNA expression. There are more than 150 distinct microRNA genes in C. elegans,
Developmental Regulation of MicroRNA Expression
EXAMINING THE EFFECTS OF HIGH PROTEIN DIET ON ADIPOSITY AND CARDIAC PERFORMANCE IN HEART FAILURE PATIENTS WITH INCREASED BODY MASS AND DIABETES. The overall goal of the study is to test the hypothesis that a high protein diet will result in sig
EXAMINING THE EFFECTS OF HIGH PROTEIN DIET ON ADIPOSITY AND CARDIAC PERFORMANCE IN HEART FAILURE PATIENTS WITH INCREASED BODY MASS AND DIABETES
A consistently replicated biological phenotype in autism spectrum disorders (ASD) is a larger head circumference (HC) in the first years of life. We hypothesize that increased brain size in ASD is attributable to altered dynamics of cell prolif
Biological Correlates of Altered Brain Growth in Austism
The purpose of this four-year study, 'School Worksite Weight Gain Prevention Intervention Study', is to determine the effectiveness of an ecological worksite intervention compared to a self-directed, print-materials only control group at reduci
School Worksite Weight Gain Prevention Intervention Study
Transforming PCI Informed Consent into an Evidence-based Decision-making Tool.
Chlamydia are human pathogens that cause sterility, blindness, pneumonia, and are strongly correlated with the number one cause of death in humans, heart disease. Chlamydia are obligate intracellular bacteria that are perpetuated through a defi
Chlamydia developmental cycle regulation by a novel transcriptional repressor
supports a research project that will run for two years. In this grant, we assess the function of Trace Amine Associated receptor 1 (TAAR1) and identifying novel polymorphisms in rhesus monkey genes associated with drug addiction and neuropsyc
Understanding how cells regulate their internal architecture is important for understanding cellular fuction, as the inside of the cell is highly organized.  Furthermore, cells in disease states frequently take on morphologies distinct from hea
Systems Biology Approaches to Identify HSP90 Functions and Substates: This grant will allow Dr. McClellan to continue her research aimed at identifying novel substrates and functions of the Hsp90 molecular chaperone.  Molecular chaperones, whic
Systems Biology Approaches to Identify HSP90 Functions and Substates
West Nile virus, an NIAID category B priority pathogen, emerged in the United States in 1999, causing over 11,000 cases of neuroinvasive disease and 1,103 fatalities. Because the threat of emerging viral diseases raises new dangers for public s
Circadian Regulation of Innate Immune Mechanisms of Viral Recognition
The mucosal surfaces of the respiratory tract are in direct contact with the surrounding environment, and as such are a primary portal of entry for human pathogens such as influenza and parainfluenza viruses.  The significant public health thre
Antigen-independent activation of memory cells during respiratory infection
T cells are involved in many beneficial aspects of the immune system including the control of infections, tumor surveillance, generation of B cell responses, and regulation of homeostasis.  In some instances, activated T cells are also detrimen
Regulation of Virus-Specific T cell Responses by TNF
By escaping signals that normally constrain dividing cells, Cancer Stem Cells display unlimited proliferative potential. Cancer Stem Cells are thought to arise from the misregulation of normal stem cells that are capable of undergoing symmetric
Proliferative control of normal and oncogenically transformed stems cells in vivo
The long-term objective of this application is to regenerate a patient-specific temporomandibular joint (TMJ) condyle using a process free of solvents, particulates and polymerization initiators. In a broader sense, this technology can be readi
Solvent-free engineering of a shape-specific osteochondral TMJ condyle
The world faces a wide array of Global Health challenges, including the HIV pandemic, the threat of an influenza pandemic, the resurgence of tuberculosis and malaria, continued malnutrition in low-income countries, and the spread of cigarette s
Framework Program for Global Health at Yale University
Anti-microbial T cell responses play a major role in determining the outcome of infection. Chronic infections are often distinguished by T cell responses that are not able to fully eliminate the pathogen. The mechanisms that explain this failur
Regulation of chronic viral infection by co-inhibitory pathways
The ability to control neuronal function in cells, tissues, and living animals is critical for understanding the role of specific proteins in neural function and behavior. Controlling protein function by light has emerged as a popular approach
OptoTFs: Geneticaly encoded light -activated transcription factors
Somatic reprogramming efforts have focused on using embryonic stem (ES) cells and their differentiated progeny to regenerate various adult tissues depleted by aging or by various pathological processes. Alternatively, this goal might be reached
Creation of adult epithelial stem cells from differentiated epithelial
The alarming increase in the prevalence of obesity is a cause of great concern given its association with many adverse health conditions, including insulin resistance and type 2 diabetes, which are associated with increased cardiovascular disea
Effects of resistant starch on lipid and glucose metabolism in insulin resistance
The use of fluorescent protein tags has revolutionized all aspects of cell biology research during the last 15 years, enabling analysis of the dynamic structures within living cells. The cloning of Green Fluorescent Protein (GFP) and the subseq
Dynamic and super-resolution imaging of endogenous proteins in Drosophila tissues
Compared to handwritten charts notes, various emerging technologies could facilitate self-documenting encounters. These technologies include speech recognition and menu-driven systems, using tablet PCs and handheld devices. However, in order fo
This application addresses broad Challenge Area (15) Translational Science and specific Challenge Topic (15-MH-105) Strategies to Support Uptake of Interventions within Clinical Community and Settings. Implementation of evidence-based treatment
Theory Driven mixed methords evaluation of PTSD treatment implementation in VA Residential Setting
This project, in response to the Enabling Technologies challenge area 06-MH-103 “New Technologies for Neuroscience Research”, will provide a powerful, content-driven approach to the identification of brains having similar geometry and shape
INFORMATICS META-SPACES FOR THE EXPLORATION OF HUMAN NEUROANATOMY
The overall purpose of the research project is to develop, using click chemistry approaches, novel antibiotics with improved activity against the major periodontal pathogens, bacteria that cause serious gum disease and tooth loss. Timely and co
CLICK CHEMISTRY FOR NOVEL ANTIMICROBIALS AGAINST PERIODONTAL PATHOGENS
Oral cancer survival has not improved for the past 20 yrs. Recently, cancer stem cell (CSC)- based therapies have shown their potential to control cancer recurrence. However, the lack of in vivo models has hindered attempts to identify markers
Identification of normal and cancer stem cells and their niche in oral mucosa
The purpose of the pilot is to estimate the effect size of the new IMET/TE system in reducing tobacco, drug, and alcohol use.  We will use these estimates and our pilot study experience to design a future study comparing iMET/TE to TAU in a muc
Dental and medical office iMET to reduce teen tobacco, alcohol, and drug use
ADPKD is a common cause of end stage renal disease (ESRD) and, hence, is of significant medical importance and economic burden. A number of different potential therapies are now in Phase III trials with the prospects for an effective therapy in
Analysis of the proteome of PKD-ELVs in polycystic kidney disease and controls
Over one million patients each year are newly diagnosed with digestive diseases, such as inflammatory bowel diseases and colorectal cancer. Digestive tracts are directly accessible by endoscopy for the diagnosis and therapy. However, current im
The goal of this project is to identify objective, quantitative bio-molecular parameters that correlate with healing outcomes for diabetic foot ulcers (DFUs). Chronic non-healing DFUs are a widespread and serious clinical problem with high rate
DEVELOPMENT OF THE CELLULAR BIOMARKER FOR DIABETIC FOOT ULCERS.
Recent studies suggest that metformin is the best oral medication for initial treatment of diabetes and that starting metformin immediately when diabetes is first detected, rather than waiting until blood sugars reach a somewhat higher target l
Effectiveness of Immediate vs. Delayed Use of Metformin in New-Onset T2 Diabetes
1. Establishing the coordinating study center (CSC) Case report forms are completed and are undergoing beta testing. The grant support continues to help retain positions within the Clinical Research Program at CHB.   Drs. Hofmann continues at 5
Development of a Pediatric Mylelodysplastic Syndrome Patient Registry
Challenge Area (11) Regenerative Medicine: 11-DK-101: Promote regeneration and repair in the digestive system, liver, pancreas, hematology, kidneys and urological system. Fecal incontinence is a condition with ramifications that extend well bey
IMPLANTATION OF PHYSIOLOGICALLY FUNCTIONAL BIOENGINEERED INNERVATED IAS CONSTRUCT
It is becoming increasingly evident that prevention of child obesity must begin very early in life, as the prevalence of child overweight in the U.S. in the past 20 years has increased even in the youngest age groups. One of the key risk factor
Prevention of Overfeeding During Infancy
The purpose of this study is to investigate potential mechanisms responsible for the delay in type 2 diabetes mellitus (T2DM) onset observed after ileal interposition in UCD-T2DM rats.  We hypothesize that IT surgery performed on prediabetic ra
Surgical Amelioration of Type 2 Diabetes: Hormones, Microbiota and Mitochondria
This proposal, entitled Vascularization of Polymeric Tissue Beds, seeks to address the broad Challenge Area of (11) Regenerative Medicine, and the specific Challenge Topic of vascular networks in engineered tissues: 11-EB-101. The major impedim
Vascularization of Polymeric Tissue Beds
This application addresses broad challenge area (14) Stem Cells and the specific challenge topic 14-EB-101 Synthetic Delivery Systems for Generating Pluripotent Stem Cells The recent advent of cell reprogramming as a means of producing induced
High throughput cell reprogramming by microfluidic jet injection
K-12 schools across the nation are implementing or considering implementing various curricula that use engineering.  From high school curricula that are fairly comprehensive (i.e. Project Lead the Way) to textbooks intended for middle or high s
Do Engineering Curricula Improve Science and Mathematics Learning in Elementary School Students?
This application addresses the broad Challenge Area (08), 'Genomics', and the specific Challenge Topic (08-ES-106), 'The role of environmental exposure in copy number variation (CNV)'. CNV events are deletions or duplications that are too small
ENVIRONMENTAL & GENETIC REGULATION OF COPY NUMBER VARIATIONS (CNV)
This project addresses 3D or virtual models to reduce the use of animals in research: Creation of miniature multi-cellular organs for high-throughput screening for chemical toxicity testing. Our long-term objective is to decrease the use of ani
The University of Montana's Air Toxics Under the Big Sky program has been used to educate high school students in rural areas of Montana, Idaho, and Alaska about indoor air quality.  In collaboration with the Alaska Native Tribal Health Consort
Air Pollution Outreach, Education, and Research Capacity Building in Alaska Native Villages
NIH identified five gateway areas to increasing public trust in clinical research: building trust through community partnerships; building relationships with patients; building partnerships with community providers; building trust in scientists
Increasing Capacity and Public Trust: A strategy for building effective sustainable
One potential result of climate change in the United States is increased frequency and intensity of wildland fires. These wildfire fires have the potential to destroy large amounts of public and private property, as was seen during the summer o
Respiratory Health Impacts of Wildfire Particulate Emissions Under Climate Change Scenarios
This application addresses broad Challenge Area 15: Translational Science and specific Challenge Topic 15-ES-101: Effects of environmental exposures on phenotypic outcomes using non-human models. Approximately 8.6 million Americans perform shif
Clock genes, environmental challenges and cardiopulmonary disease
The goal of this project is to develop and evaluate a theory-driven pedagogic minimal Geographic Information Systems (mGIS) interface to enhance spatial thinking, analysis, and learning in science, technology, engineering, and mathematics (STEM
Exploiting the power of geographic information systems to enhance spatial thinking in the science, technology, engineering and mathematics areas
Millions of individuals world-wide use aspirin for cardioprotection yet clinicians currently lack a reliable tool to accurately identify those patients who will develop myocardial infarction (MI) or stroke despite aspirin use. Our long-term goa
PHASE I CLINICAL TRIAL DESCRIBING THE PHARMACOGENOMICS OF ASPIRIN
This application addresses broad Challenge Area (06) Enabling Technologies and specific Challenge Topic 06-GM-102* .Chemist/biologist collaborations facilitating tool development. The objective of this grant is to develop fluorescent chemical t
Fluorescent Chemical Tags for Single-Molecule Imaging in Cells
This application addresses broad Challenge Area (06) Enabling Technologies and specific Challenge Topic, 06-HD-101 Improved interfaces for prostheses to improve rehabilitation outcomes. Considerable progress has been made during the last decade
This study will determine the effectiveness, mechanism, and safety of 5 treatments of 6-Hz primed low-frequency repetitive transcranial magnetic stimulation (rTMS) applied to the non-stroke hemisphere and combined with constraint induced therap
Pediatric Hemiplegia: Synergistic Treatment using rTMS and CIT
Development of the PediaFlow Pediatric Ventricular Assist Device
Develop the three portals for entry of patient generated family history data integrated with an EHR. The pathways will include: : (1) computer tablets in waiting rooms to complete the MFHP, (2) a secure internet portal to transfer data collecte
Integrating Patient Generated Family Health History from Varied EHR Entry Portals
This application addresses broad challenge area (01) Bioethics, and specific Challenge Topic, 02-HG-101: Informed Consent and Data Access Policies. Our project title is 'The Impact of Data Access Policies on Biobank Participation'. The NIH data
Impact of Data Access Policies on Biobank Participation
The number of human samples undergoing whole-genome sequencing is expected to increase dramatically in the next few years, as advances in next-generation sequencing technologies continue to lower the cost of sequencing. In addition to detection
Statistical Methods for Estimation of Copy Number from Next-Generation Sequencing
This application addresses broad Challenge Area: (04) Clinical Research and specific Challenge Topic: 04- HL-104: Perform Secondary Analyses of Existing Data to Answer Important Clinical and Preventive Medicine Research Questions. Coronary reva
ARRA Funded:  Long-Term Survival Following Coronary Revascularizations
ARRA - Weight-Related Measures and CVD in African American and White Adults  We will use the population-based samples of African American and White men and women in the Atherosclerosis in Communities Study (ARIC) to examine associations of a ob
ARRA - Weight-Related Measures and CVD in African American and White Adults
We propose to tackle the challenge (06-HL-103) of providing enabling technologies directed towards developing novel quantitative imaging approaches for the measurement of coagulation enzyme function in the intact mouse to improve basic understa
NOVEL TECHNOLOGIES FOR IMAGING BLOOD COAGULATION REACTIONS
This application addresses broad Challenge Area (04) Clinical Research, and the specific Challenge Topic 04-HL-103 Assess the role of leukocyte interaction with platelets, erythrocytes, and endothelium in the pathogenesis of heart, lung, and bl
INHIBITION OF PLATELET-LEUKOCYTE INTERACTIONS TO TREAT TRALI
A fundamental limitation in understanding the pathogenesis of congenital heart disease has been the lack of model systems to study human heart development. Studies in model organisms have been informative, but clearly interspecies differences e
Characterization of Cardiac Progrenitors Derived from 22q11-deleted Patients
Smoking Interventions for Hospital Patients: A Comparative Effectiveness Trial Project Summary/Abstract The Challenge: This application addresses broad Challenge Area (04), Clinical Research, and specific Challenge Topic, 04-HL-116: Cost-effect
Smoking Interventions for Hospital Patients:A Comparative Effectiveness Trial
Sleep loss is a major American health problem. The proposed studies will determine a biomarker for sleep loss.  We hypothesize there are molecular signatures that reflect the state of sleepiness.
Biomarker for Sleep Loss: A Proteomic Determination
This application addresses broad Challenge Area (05) Comparative Effectiveness Research and specific Challenge Topic (05-HL-102) Treatment of Obstructive Sleep Apnea. About 15-30% of obstructive sleep apnea (OSA) patients have a poor tolerance
ARRA Targeted Therapies for Selected Phenotypes of Obstructive Sleep Apnea
A new generation of highly selective, protease-specific anticoagulant drugs is entering clinical applications, but we have an incomplete understanding of how these drugs attenuate inflammatory processes in cardiovascular diseases, obesity, auto
Toward a Repertoire of Genetic Models of Coagulation Signaling in Chronic Inflammation
MAHARISHI UNIVERSITY OF MANAGEMENT RESEARCH INSTITUTE
The broad Challenge Area is: 09 Health Disparities. The specific Challenge Topic is: Develop tools to detect early indicators of health disparities, and to test collaborative interventions to reduce differential health care or outcomes for hear
RCT of Stress Reduction in the Secondary Prevention of CHD in African Americans
This application is in response to Challenge Area 04-HL-104, 'Perform secondary analyses of existing data to answer important clinical and preventive medicine research questions.' The specific topic is #8, 'Analysis of genetic markers related t
Genome-wide and Linkage Study of Quantitative Emphysema Phenotypes
This application addresses broad Challenge Area (06) Enabling Technologies and specific Challenge Topic, 06-HL-105: Develop transgenic animal models that are informative for understanding chronic inflammation in humans. Chronic noncommunicable
Serum amyloid P and chronic noncommunicable diseases
This application addresses broad Challenge Area (15) Translational Science, and specific Challenge Topic 15-OD(ORDR)-101* 'Pilot projects for prevention, early detection and treatment of rare diseases.' Lymphangioleiomyomatosis (LAM) is an ofte
The Lymphangioleiomyomatosis (LAM) Genome Atlas
Neural cell adhesion molecule (NCAM) is key in leucocyte adhesion to endothelial cells.  Upon signaling by chemokines such as MCP1 leukocytes fall into the area of endothelial cells.  Tethering of the endothelial cells to leukocyte cadherins is
Estradiol-Induced Sialyation of NCAM prevents Leucocyte: Endothelial Adhension
This application addresses broad Challenge Area (15) Translational Science and specific Challenge Topic, 15-HL-104: Characterize the role and effects of the respiratory and/or intestinal microbiota on the presence and clinical phenotype of lung
Our major purpose for this project is to identify novel biomarkers of risk for VTE among approximately 3,500 plasma metabolites detected by mass spectrometry based analysis. Work began on this project September 30, 2009 and the expected outcome
Venous Thromboembolism and Mass Spectrometry-based Untargeted Metabolomics
DESCRIPTION (provided by applicant): This application addresses broad Challenge Area (07): Enhancing Clinical Trials, and specific Challenge Topic, 07-OD(ORDR)-101* Library of Standardized Patient Registry Questions. The primary objective of th
LIBRARY OF STANDARDIZED PATIENT REGISTRY QUESTIONS FOR RARE DISEASES
The North Lawndale Diabetes Community Action Project addresses Challenge Area Comparative Effectiveness Research and the specific Challenge Topic 05-MD-102 Prevention of Chronic Diseases in Disparity Populations. The Sinai Urban Health Institut
The North Lawndale Diabetes Community Action Program (NLCAP). In the North Lawndale community the program is known as Block by Block North Lawndale.
Using new technologies to improve or measure adherence. The primary aim of this research is to develop and test a method for increasing adherence to treatment recommendations for mothers of children with emotional or behavior problems. Parental
Parents' Adherence to Treatment Recommendations:  Do It For The Children
This application addresses broad Challenge Area (15) Translational Science, 15-MH-109: Prefrontal cortex regulation of higher brain function and complex behaviors, which is directed to examine mechanisms by which the developing and mature prefr
PREFORNTAL CORTEX BDNF AND AMYGDALA-DEPENDENT EMOTIONAL
Schizophrenia is a devastating mental illness that affects approximately 1% of the global population.  Symptoms of schizophrenia can be grouped into three categories: positive symptoms, such as hallucinations; negative symptoms, such as social
IN VIVO METHODS FOR PRECLINICAL ANALYSIS OF COGNITIVE THERAPIES FOR SCHIZOPHRENIA
Developing a Community-Based ASD Research Registry This application addresses Broad Challenge Area 05 (Comparative Effectiveness Research) & Specific Challenge Topic 05-MH-104 (Building ASD Registries for Use in Comparative Effectiveness Resear
DEVELOPING A COMMUNITY-BASED ASD RESEARCH REGISTRY
This application addresses NIMH broad Challenge Area (04) 'Clinical Research' and specific challenge topic 04-MH-102: 'refining categories of clinical phenotypes for mental health research purposes'. We propose an innovative study aimed at refi
Paternal Age Related Schizophrenia as a  Discrete Disorder
This project from Virginia Commonwealth University proposes to address the challenging goal of translating best practices into the community and subsequently improving health outcomes in minority, underserved and vulnerable populations by build
Community Partnership for Ethical Research
This application addresses broad Challenge Area (04) Clinical Research and specific Challenge Topic, 04-OD-101: Develop and Validate Behavioral Metrics to Measure the Impact of Chronic Pain. Acute pain is a normal sensation triggered in the ner
Development and Validation of Measures of Pain Behaviors in Chronic Pain (ARRA Pain Metrics)
This application addresses Challenge Area 06, Enabling technologies; Specific challenge topic 06-MH-103, 'New technologies for neuroscience research' MicroRNAs are believed to contribute to schizophrenia, autism, Tourette's syndrome, mood disor
MicroRNA networks in synaptic plasticity
This application addresses the broad Challenge Area (05) Comparative Effectiveness Research and the specific Challenge Topic: 05-NS-104* Intervention vs. Best Medical Therapy in Asymptomatic Persons With Identified Vascular Abnormalities. The I
Predictors of Long-Term Outcome of Unruptured Intracranial Aneurysms
DESCRIPTION (provided by applicant): Challenge Area: (03) Biomarker Discovery and Validation Challenge Topic: Discovery of biomarkers for disease risk, progression or response to therapy in diseases of interest to NIDDK. 03-DK-101 Title: Biomar
This application addresses broad Challenge Area (08) Genomics, and specific Challenge Topic 08-CA-101* Augmenting Genome-Wide Association Studies. The development of glioblastoma (GBM) has been hypothesized to be associated with relatively comm
Identification of 9p and 20q Germline Alterations in Glioblastoma Pathogenesis
A wide variety of genetic or drug-induced mental health disorders have been linked to problems in regulation of gene expression. Gene expression is regulated by specialized proteins called transcription factors (TFs), which work with a few nucl
DEVELOPMENT OF SPLIT DAMID AS AN ALTERNATIVE METHODOLOGY TO CHROMATIN IMMUNOPRECI
DESCRIPTION (provided by applicant): This application addresses broad Challenge Area (13): Smart Biomaterials - Theranostics, and specific Challenge Topic, 13-NS-101: Developing novel biomaterials to interfaces with neural activity. Implantable
Micro-thread arrays for long-term and high fidelity neural interfaces
Epilepsy affects over 1% of the US population, and up to 30% of people suffering from epilepsy do not respond to conventional antiepileptic drugs (AEDs). The newly FDA-approved AED vigabatrin has improved efficacy in this population yet its use
Attenuating the retinal and CNS adverse effects of vigabatrin with NKCC1 inhibitor
The Food and Drug Administration Amendments Act (FDAAA) requires FDA to obtain access to multiple distributed large claims and electronic medical records databases covering 100 million lives by 2012. The pooled database will provide sufficient
Effectiveness studies with securely pooled healthcare data and adjusted analyses
Dramatic advancements in nanomagnetic sensor technology, driven by the needs of magnetic data storage industry, have now brought us disk drives with magnetic read heads addressing features of less than 80nm across, at a wholesale cos
Single-molecule nanomagnetic assays for ultrasmall sample clinical diagnostics
The goals of this project are to perform assay related to diabetes, lipid metabolism and coronary disease in the Pakistan Risk of Myocardial Infarction Study (PROMIS). This project will generate novel data  regarding the links between T2DM and
Markers of the metabolic syndrome linking type 2 diabetes and MI in South Asia
DESCRIPTION (provided by applicant): Abstract: The mechanisms of action of alcohol (ethanol) and nicotine on the nervous system have been studied extensively. However, it was not until a few years ago that microglia were recognized as an import
Mechanism of Alcohol and Nicotine Interaction
The Go grant award funded a 2-year research project investigating a new modality of therapy directed at memory impairment in the elderly. Aging is often associated with cognitive deficits, especially decline in memory functions that depend on t
BRIDGING COGNITIVE AGING IN RODENTS TO MAN USING FMRI IN AMNESTIC MCI
Facioscapulohumeral muscular dystrophy (FSHD) is a genetically dominant progressive myopathy affecting  approximately 25,000 individuals in the United States. It is the third most common muscular dystrophy by  incidence with a prevalence near o
FSHD iPS Cells: Modeling Disease Mechanisms,Genetic Correction and Cell Therapy
We propose to develop a unique approach to promoting wound healing by engineering of the wound bed. The unique approach we propose will result in changing the intrinsic properties of the wound bed to promote favorable outcomes. We will exploit
Beyond Biomaterials: Engineering the Wound Bed
Burns are one of the most common and devastating injuries known to mankind. Each year in the US approximately 500,000 patients with burns present to emergency departments. Of 40,000 annual hospitalizations, 25,000 burn victims are admitted to s
ARRA: Novel Peptide to Inhibit Burn Injury Progression
The Radiation Therapy Oncology Group (RTOG), which is one of the largest and most established cooperative groups in oncology, has developed a recursive partitioning analysis (RPA) model for malignant glioma patients, using primarily clinical an
RTOG ARRA Program-Towards A Refined Molecular Recursive Partitioning Analysis Model For Glioblastoma
The overarching goal of this project is to develop a coordinated, multidisciplinary center for the generation and synthesis of evidence to support the translation of genomic tests into improvements in cancer prevention, screening, diagnosis, tr
Comparative Effectiveness in Genomic Medicine
The award 'Predicting pancreatic cancer responses for a Parp inhibitor-based clinical trial' is part of a larger effort by our group to identify the genetic basis of pancreatic cancer and to use that information to develop personalized therapie
PREDICTING PANCREATIC CANCER RESPONSES FOR A PARP INHIBITOR-BASED CLINICAL TRIAL
Our understanding of how cancers begin, survive and progress is rapidly expanding through advances in cancer genomics and modern cancer biology.   In assembling the Target Discovery and Development Network (TDDN), the NCI has undertaken the mis
Targeting Causal Cancer Genes with Small Molecules
It is now quite clear that a subset of patients with metastatic melanoma treated with CTLA-4 blocking antibodies have durable clinical benefit. The experience of our group and others leads us to several vital questions which require answers so
Defining the Importance of Immunity to NY-ESO-1 in Melanoma Therapy and Prognosis
There is increasing evidence that antibodies targeting the CD4 induced (CD4i) epitopes on the HIV envelope spike can facilitate control of viremia and quite possibly protection from transmission after exposure (reviewed in (1, 2)). We have deve
FLSC Combined with Tat Toxoid as an HIV Prophylactic Vaccine
Improvements in cancer screening effectiveness, higher participation rates and faster introduction of new screening tests could have pronounced effects on the health of the community by reducing cancer burden. Cancer screening effectiveness in
SEARCH: Cancer Screening Effectiveness and Research in Community-basedHealthcare
Lymphocytes bearing high levels of FasL are known to suppress cell-mediated immunity and destroy the efficacy of DNA vaccines. Their ability to kill the antigen-presenting cells can be eliminated by several different mechanisms and we are explo
Protection of vaccine immunity by inhibiting Fas/FasL signalijng
HIV infection is associated with increased incidences of multiple tumors, many of which are associated with oncogenic tumor viruses like KSHV, Epstein-Barr virus (EBV), or human papillomavirus (HPV). HIV infection is a worldwide health issue af
Development of Novel Vaccine Approach against Gammaherpesvirus Infection in Prim
This application is in response to Grand Opportunity (GO) RFA-OD-09-004 for Exploratory Research in the Development of Vaccines for AIDS-associated Malignancies. We will focus explore using the Epstein-Barr virus as a persistent vaccine vector
Epstein-Barr Virus: A persistent vaccine vector
Conducting timely, high quality, comparative effectiveness research (CER) and creating and delivering recommendations for genomic tests in cancer care and prevention are major technical and intellectual challenges. Yet with the increased use of
Building a Genome Enabled Electronic Medical Record
Tobacco usage remains one of the most prevalent forms of substance abuse and exerts a tremendous cost on the world health and economy. While it is known that nicotine is the major component in tobacco smoke responsible for addiction, we current
A QUANTITATIVE PROTEOMICS PLATFORM TO CHARACTERIZE THE NICOTINE-DEPENDENT BRAIN
Accidental or purposeful exposure of people to high levels of radiation poses a serious immediate risk and potential long-term health risk. NO FDA approved radiomitigant effective 24-48h after radiation injury is available today. Thus, there is
Preclinical Development of a GI Radiation Countermeasure
Chronic pain is a major public health problem that is only growing worse as the gaps in our knowledge base continue and the population at risk grows.  We believe we have a cost effective solution that could become a model for other pain managem
Comparative Effectiveness of Interventions for Chronic Pain Management
This project addresses the design of cellular and animal screening procedures that can be used to assess the potential danger of engineered nanomaterials that are currently being introduced into the marketplace.  We will develop a predictive to
PREDICTIVE TOXICOLOGICAL PARADIGMS TO ESTABLISH INHALATION TOXICOLOGY MODELS
Zeiss Laser Scan Microscope (LSM) 510-duo - Recent advances in technology of confocal microscopy have opened new avenues for understanding the biology of cells and their interactions with other cells. For example, now that we can examine living
Zeiss Laser Scan Microscope (LSM) 510-duo
A new era of genetic research is now upon us with the arrival of massively parallel, high throughput, whole genome DNA sequencers.   These new instruments allow avenues of genetic inquiry for advanced scientific laboratories that were impossibl
COMPUTER CLUSTER AND STORAGE TO SUPPORT WHOLE GENOME SEQUENCING AND ANALYSIS
Tennessee State University, College of Health Sciences
The purpose of the SDS award is to provide scholarships for students that need financial assistance to continue their education.   Preference for this scholarship will be given to nursing students from whom the cost of attendance to the univers
This project has not started here and is in process of being relinquished to the PI's new Institution.
The Role of Type III Interferon in Innate Immunity to Respiratory Virus Infection
The purpose of this three year funding initiative is to assist the Maryland Primary Care Office (PCO) in the coordination of activities related to the delivery of primary care services and the recruitment and retention of critical health care p
The Michigan Primary Care Office (PCO) will utilize funding through this grant program to coordinate activities within Michigan related to the delivery of primary care services and the recruitment and retention of critical health care providers
Construction of sewer system for Woodlands of Millsboro Sanitary Sewer District
Highway Infrastructure Investment Grant: Areas with  Population equal to or less than 200K
San Francisco National Wildlife Refuge Complex Phase Two of building renovations: envelope and finises renovations in HQ levels 1 & 2 and all other areas of HQ levels 3 & 4; including relocation of modular office.  This action includes incident
ARRA Program Management -- overseeing various infrastructure projects through completion.
BUCKLAND HILLS AND HALE ROAD PAVEMENT REHABILITATION
Safety and Resurfacing Brokenland Parkway to Middle Patuxent River
Cedar Lake Trail - Third Ave N connection along 3rd Ave N from 12th St N to 7th St N
OJT/SS Trainee Program Commercial Drivers Licensing (CDL) Training and Certification for Women and Minorities
ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start and Early Head Start program.  Head Start promotes the school readiness of low-i
This award provides for ARRA Cost of Living Adjustment (COLA)and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start program. Head Start promotes the school readiness of low-i
Head Start 2009 ARRA COLA Quality Improvement Funding. Funding used to increase wages for employees, to initiate an employer contribution to retirement, to provide professional development for teachers and to purchase safety vests for children
ARRA COLA Quality funds will be used for: increased pay of current staff to include ARRA COLA increase of 1.84% for better retention and recruitment. Increased hours of program staff - particularly in the areas of education, family service and
MID WILLAMETTE VALLEY COMMUNITY ACTION AGENCY INC
On-going Cost of Living Adjustment (COLA) of 3.06% for all Head Start employees.  Quality Improvement funds utilized for a 12-month period to provide 1.84% COLA & wage increases varying between 6%-8% for all Head Start employees.
EDUCATIONAL OPPORTUNITIES FOR CHILDREN & FAMILIES
HEAD START 2009 COLA-QUALITY IMPROVEMENT
SKAGIT VALLEY COLLEGE EDUCATION ASSOCIATION
Head Start 2009 ARRA COLA Quality Improvement funding
This award provides for ARRA Cost of Living Adjustment (COLA), and quality Improvement Funding consistent with the provisions of Section 640(a)(5)of the Head Start Act for the Head Start and/or Early Head Start program.  Head Start promotes the
Cost of Living adjustment of 1.5% to all staff effective 8/1/09. Hired two staff part time staff to support children with disabilities and professional development. Funding will also provide support for employee benefits.
, was awarded the grant through the American Recovery and Reinvestment Act to Portland Public Schools to provide Head Start services to 40 additional children for the period of 9/30/09 to 9/30/11.  These funds support two extended-day option cl
WESTERN IDAHO COMMUNITY ACTION PARTNERSHIP
Balance of $1,330 not spent on SH0077/01.  PMS shows $3,345, so I do not know if I am allowed to draw the difference at this point.  Please advise.  This award provides for ARRA Funding consistent with the provisions of the Head Start Act for t
This award provides for ARRA Early Head Start Expansion funded to serve 72 children and ARRA Head Start Expansion to serve 18 children.  The Early Head Start and Head Start programs provide family-centered services for low-income families with
The Alaska Association of Conservation Districts (AACD) will work with the USDA Forest Service to oversee and coordinate invasive plant (IP) programs thoughout Alaska via coordinator positions stationed at Soil and Water Conservation Districts
Highway Infrastructure Investment Funds- Federal Lands Project
Critical road and recreation site recovery.
Renovate and upgrade the Emory L. Bennett State Veterans Nursing Home located in Daytona Beach, Florida.
Comm/Pack Chicken, Fozen Whole Bagged 36-43 lb ct; 2 loads of 39,600# each to deliver between 7/1/09 and 7/31/09.
Park and Ride Expansion at Blythe Dale Road
The application submitted by ESRHS to USDA requested funding for long term financing to build a 20,000 square foot facility to replace the former Onley Community Health Center and a grant of $50,000 to purchase equipment for the new facility.
Construction of Onley Community Health Center
Resurfacing East of Big Mill Pond to Linkwood Road
Cooperative agreement between the USFWS and Lower Elwha Tribe to construct and obtain the necessary permits to to install a fish management weir in the Elwha River for the purposes of monitoring and ennumerating adult salmon returns to the Elwh
This Cooperative Agreement is being implemented for the purposes of : 1) helping to reverse the trend of declining fish and wildlife habitat by removing an old irrigation dam that is a barrier to migrating fish (near City of Ellensburg, Kittita
Wastewater Treatment Plant Improvement Project
Watewater Treatment Plant Improvement Project
Support restoration actions in the 43 acres of the Miami River wetlands in Tillamook County.
Miami Wetlands Restoration Implementation in Tillamook Bay
Plan development of selected Alt. from Concept Study.
This contract is a three year phase project to preserve the brick struture at Fort Jefferson, Dry Tortugas National Park.
Upper Cub River Fish Passage Restoration--This award is being used to install a fish screen at an irrigation diversion on the Upper Cub River near Preston, ID, to prevent entrainment and mortality of Bonneville cutthroat trout and other native
Upper Cub River Fish Passage Restoration Project
WESTERN CAROLINA HIGHER EDUCATION COMMISSION
This is a continuation proposal (Year 2) for Salkehatchie Lures and its related tourism product, Salkehatchie Stew, initially funded by an RBEG in early 2008. Together, they form a community and economic development/tourism project with the pot
Technical Assistance for the second year of the Salkehatchie Stew and Lures projects and also continued economic development and tourism efforts in Salkehatchie Region of South Carolina.
Federal project 1501007, involving placing pit run subbase, bituminous pavement surfacing, chip  seal and miscellaneous work on 6.83 miles of WYO 291, beginning at reference marker 2.68,  between Cody and South Fork (Cody West) in Park County.
Funding to construct a 10 inch 3000 foot culinary water line to provide a reliable source of drinking water and fire protection to Brigham City Residents.
BIN 3305570, WARRENSBURG RD (CR3) OVER STONY CREEK, WARREN
DELAWARE AVENUE ROAD RECONSTR, ALBANY CITY
The face distinguishes one human being from another. When the face is disfigured from injuries, tumor resection, congenital anomalies or infectious diseases, the patient experiences both physical and psychosocial trauma, and therefore has stron
Regeneration of Clinically Relevant Orofacial Tissues in Pre-Clinical Models
Modulating Cortical and Sub-cortical Brain Circuits in Chronic Facial Pain Chronic pain, especially facial pain is difficult to treat because it is associated with an enormous diversity of nervous system alterations. Characterizations of these
Modulating Cortical and Sub-Cortical Brain Circuits in Chronic Facial Pain
This application proposes large-scale sequencing and genotyping in type 2 diabetes (T2D) case-control samples, addressing one of the major questions in human genetics: how and to what extent can insights into disease etiology be advanced by stu
LOW-PASS SEQUENCING AND HIGH-DENSITY SNP GENOTYPING FOR TYPE 2 DIABETES
Bisphenol A (BPA) is one of the highest production chemicals in the world. It is used in polycarbonate beverage containers, food packaging, linings of food cans, and sealants for teeth. Public health concerns have been raised about BPA because
Bisphenol A and Children's Growth and Development
This topic specifically targets developing a deep and diverse understanding of genetic maps and recombination within and between species, which is what our proposal intends to study. Project Title: Fine-scale recombination rate variation within
Fine-Scale Recombination Rate Variation within and Between Drosophila Species
Project Summary/Abstract This application addresses Grand Opportunity: Phase 2 Clinical Trials Program of Novel Therapies for HLB Diseases. Obstructive sleep apnea (OSA) afflicts > 5% of adults and is associated with a 2 to 4-fold increased ris
Phase II Trial of Sleep Apnea Treatment toReduce Cardiovascular Morbidity
This proposal is in response to the NHLBI's call for 'Novel Methods of Monitoring Health Disparities.' The University of Wisconsin (UW) School of Medicine and Public Health (SMPH) and its partners propose to build an innovative research network
Novel population health approach to address CVD and pulmonary health disparities
The need for a more efficient and effective infrastructure for clinical research has been articulated by ARRA, as well as by the NIH clinical roadmap initiative. One of the greatest national inefficiencies of the current model of clinical resea
ACC/Duke Partnership for a National Cardiovascular Research Infrastructure (NCRI)
Self-renewal is essential for the homeostasis and lifetime maintenance of many organ systems. The process of self-renewal is carried out by rare populations of adult stem cells whose key features are multilineage potential and repopulating capa
DYNAMIC REGULATION OF THE EPIGENOME DURING HEMATOPOIETIC DIFFERENTIATION
Coronary heart disease is the leading cause of mortality in both men and women worldwide and incidence is highly correlated with levels of cholesterol and triglycerides (fat) in the blood.  Plasma concentrations of LDL and HDL cholesterol, as w
Molecular mechanisms and pathways of novel genomic loci regulating plasma lipids
This research proposal, entitled 'Building on GWAS for NHLBI-diseases: the U.S. CHARGE consortium', will leverage existing population, laboratory and computational resources to identify susceptibility genes underlying genome-wide significant an
BUILDING ON GWAS FOR NHLBI-DISEASE: THE CHARGE CONSORTIUM
The purpose of the award is to translate important new concepts in cellular therapies to the clinic. The project will focus on 4 key projects using different cellular based therapeutics that have shown exceptional promise in preclinical models
Regulatory T Cells in Allogeneic Transplantation
This application addresses the NHLBI-RFA-OD-09-004 for Large-scale DNA Sequencing and Molecular Profiling of Well-phenotyped NHLBI Cohorts. We propose to establish a sequencing center to perform the production-level resequencing of exomes from
This application responds to the NHLBI 'Grand Opportunities' RC2 topic, 'Large-scale DNA Sequencing and Molecular Profiling of Well-Phenotyped NHLBI Cohorts.' We will use whole genome resequencing to identify genetic changes relevant for the pa
WHOLE GENOME SEQUENCING OF MYELODYSPLASTIC SYNDROMES
The representation of minorities in public health and biomedical research still lags behind that of whites.  This represents an ongoing challenge to the validity and generalizability of research findings, which consequently contributes to dispa
Building Trust Between Minorities and Researchers
We propose a method for answering critical questions concerning the social determinants of health and health disparities by linking 30 years of comprehensive, nationally-representative sociological data to prospective mortality data containing
A Dataset for the Study of the Social Determinants of Health
Schizophrenia is a common profoundly disabling disorder that carries a heavy burden for patients and families and is the subject of intensive genetic studies. The study of epigenetic variation is an essential complement to conventional genetic
1/5:FAMILY-BASED GENOME-WIDE METHYLATION SCAN IN SCHIZOPHRENIA
The muscular dystrophies are complex genetic diseases characterized by inherited or sporadic defects in genes that encode muscle proteins. Although Duchenne (DMD), Becker, limb girdle, congenital, facioscapulohumeral, myotonic, oculopharyngeal,
TrkB.T1 as a Genetic Disease Modifier of Muscular Dystrophy
iPS Cells As Models of ALS: To gain an understanding of the mechanisms underlying any given disease requires access to relevant cell classes on the same genetic background. Although ALS research has seen significant advances over recent years,
GENERATION AND CHARACTERIZATION OF AMYOTROPHIC LATERAL SCLEROSIS IPS CELLS
Parkinson's disease (PD) is a neurodegenerative disorder characterized by death of substantia nigra (SN) dopamine neurons (DANs), dopamine deficiency within the striatum and a clinical movement disorder. Most PD is sporadic/idiopathic that may
A Novel Monkey Model for Parkinson's Drug Discovery
This is a proposal to explore the role of RNA dysregulation in the pathogenesis of amyotrophic lateral sclerosis (ALS). The work stems from recent findings that rare patients with familial ALS have mutations in RNA binding proteins. We will use
This application addresses the broad challenge area (06) Enabling Technologies and the specific Challenge Topic of 06-ES-102: 3-D or Virtual Models to Reduce Use of Animals in Research: Creation of Miniature Multi-Cellular Organs for High Throu
3D SKIN MODEL TO TEST TOXIC AND SENSITIZING POTENTIALS OF ENVIRONMENTAL CHEMICAL
In this proposal  six faculty of the Departments of Biology and of Chemistry at MIT request funding for automated macromolecular crystallization equipment to be installed at MIT's Structural Biology Core Facility. MIT structural biologists have
Acquisition of Automated Nanoscale Crystallization Equipment
Structural analyses of cellular and tissue components provide important information regarding normal function and pathological conditions. The high-resolution transmission electron microscope and accessories requested in this application will b
The purpose of this proposal is to facilitate the purchase of a 3T MRI scanner for basic and applied research at Cornell University. This 3T scanner will be the first MRI research instrument at the Cornell Ithaca campus, providing capabilities
3T MR SCANNER FOR IMAGING FROM MICE TO HUMAN
It is proposed to expand the capability to perform modern multi-nuclear solid state NMR experiments at the University of Washington by replacing an obsolete, home-built single r.f. channel 500 MHz. NMR console with a commercial triple channel s
SOLID STATE NMR CONSOLE AND PROBE UPGRADE FOR BIOPHYSICAL AND BIOMATERIAL STUDIE
We request funds to purchase multiple instruments that will increase the throughput capacity of the DNA Analysis Facility on Science Hill (DAFSH) at Yale University. Currently DAFSH is functioning as a medium-throughput, fee-for-service and non
High-Throughput Genetic Analyzer Upgrade for Comparative Population Genomics
In this application, we are requesting an ICP-MS (Inductively Coupled Plasma Mass Spectrometer) for the Metal Ion Core in the Department of Biochemistry and Molecular Biology at OHSU. An ICP-MS determines the concentration for elements from Li
ICP-MS to Measure Elemental Concentrations
Key to the success of gene and gene expression studies is equipment capable of reproducibly measuring levels of gene expression and gene mutations using preciously small amounts of starting material.  For both gene and gene expression studies R
The goal of this proposal is to bring an Applied Biosystems 4000 QTrap hybrid tandem mass spectrometer with nano-CD to the Proteomics Core at Wayne State University. This instrument, has unique capabilities for discovery of post translational m
4000 QTRAP FOR DISCOVERY AND QUANTITATION
, is jointly submitted by NIH-supported investigators at Duke University and the University of North Carolina who primarily conduct neuroimaging research at the Duke-UNC Brain Imaging and Analysis Center at Duke University Medical School. The c
A LINUX CLUSTER COMPUTATIONAL FACILITY FOR NEUROIMAGING RESEARCH
The primary intent for the confocal core is to substantively advance the science of a selected groups of NIH funded projects here in the Translational Research Building at the University of Pennsylvania.  The secondary goals with this new equip
Confocal Microscope Core for Translational Research
Funds are requested for the acquisition of Ultraflex III TOF/TOF 200 MALDI- TOF Mass Spectrometry Imaging System, an up-to-date Ultraflex III TOF/TOF200 modular time-of-flight mass spectrometer together with corresponding software and accessori
ULTRASPEC III TOF/TOF 200 MALDI-TOF MASS SPECTROMETRY IMAGING SYSTEM
This award is for $1,944,611.50 in direct costs from the National Center for Research Resources (NCRR) High-End Instrumentation Grant Program (S10) to fund a crucial 3T quasar dual MRI scanner for multimodal and molecular imaging. This new inst
3T Quasar Dual MRI Scanner for Multimodal and Molecular Imaging
Scholarhips for Medical and Pharmacy students from disadvantaged backgrounds.
Scholarships for students from disadvantaged background that are eligible in physician assistant health profession. The program trains students in Primary Care. A total of 20 students were awarded. All funds were exhausted.
SOUTHERN UNIVERSITY AND ANM COLLEGE SYSTEM
ARRA Scholarships for Disadvantaged Students are under funds provided by the U.S. Department of Health and Human Services, Health Resources and Services Administration through the American Recovery and Reinvestment Act of 2009 to nationally acc
ARRA  - Scholarships for Disadvantaged Students
Program provides scholarship funds to financially needy students from disadvantaged backgrounds enrolled in health professional programs and helps reduce the loan amounts students need to obtain to meet their educational expenses.
HHS/HRSA Scholarship for Disadvantaged Students
EMERGENT PRODUCT DEVELOPMENT GAITHERSBURG INC.
Advance the development of the next generation anthrax vaccine, dmPA7909, to meet the nation's needs for an anthrax vaccine which will facilitate the following:  1. Rapid Immune response following 2-3 doses 2. Long-term stability to facilitate
Development of a Next Generation Anthrax Vaccine, dmPA7909
This project will produce two bivalent dengue vaccine constructs based on adenovirus vectors. A tetravalent vaccine comprising two bivalent components will be tested in pre-clinical animal model systems.
Tetravalent dengue vaccine based on complex adenovirus vectors
The Nursing Initiative Promoting Immunization Training (NIP-IT) program is a web-based curriculum about immunizations and vaccine preventable diseases designed to educate nursing students and nurses across the country. It was developed in a coo
ARRA-PARTNERSHIPS TO ADDRESS IMM. TRAINING FOR NURSES, OTHER HEALTH STAFF, COAL
Innovative therapies to eliminate persistent HIV infection ARRA Project 1:  Novel Therapeutics to Target HIV Latency -Evaluate novel HIV inducer activity in vitro and in vivo -Perform molecular profiling studies of novel inducers of HIV express
Innovative therapies to eliminate persistent HIV infection ARRA
Nine institutions of different sizes, geographical location, and culture have come together to build and implement a Federated National Informatics Network that will allow any investigator across America to discover research resources that are
Networking Research Resources Across America
Funding will assist the Minnesota Primary Care Office (PCO) in strengthening the primary care workforce administered through the National Health Service Corps (NHSC), specifically to help meet the demand to recruit, clinicians into the program,
The West Virginia Department of Education (WVDE) received funds through the American Recovery and Reinvestment Act of 2009 (ARRA) to assist in the purchase of equipment for School Food Authorities (SFAs) participating in the National School Lun
1900 Kanawha Boulevard East Building 6 Room 248
Tuberculosis is a leading AIDS-associated, opportunistic infection and globally it has been estimated that twenty percent of AIDS patients die from tuberculosis. In this study we propose to explore and develop a novel class of nitroaromatic ant
The overall goals of this project are to investigate the role(s) of the NG2 proteoglycan in mammary tumor vascularization and progression. For this purpose we will utilize the MMTV-PyMT transgenic mouse model of breast cancer. Preliminary exper
NG2-PG in Tumor Vascularization & Progressions
This grant will extend our studies on the role of ATF2, a transcription factor and DNA damage response protein, in melanoma development and progression. Our preliminary results point to the function of ATF2 as an oncogene in malignant melanoma.
ATF2 in melanoma development and progression
We believe that how one reacts to the discomfort of nicotine withdrawal and quitting smoking is a promising avenue of investigation and may have important treatment implications.  We have proposed that the inability to tolerate the distress of
Distress Tolerance Treatment for Smoking Cessation
Mice with a null mutation of the homeobox gene Hhex die mid-gestation with multiple developmental defects, including complete absence of the liver. Recently, we derived two strains of mice with a deletion of Hhex in the developing liver - at E9
Hhex- A Homeobox Gene Necessary for Liver Development
Foundations will be laid in this proposal for use of both functional magnetic resonance imaging (fMRI) maps and resting state functional connectivity maps to study brain plasticity that occurs following surgery to repair peripheral nerves injur
Preeclampsia and intrauterine growth restriction are serious complications of pregnancy that endanger maternal and fetal health. Its most severe cases are associated with a fetal mortality of 50%. In this application we propose to study the mec
Targeting Placental Pathophysiology in IUGR and Preeclampsia
Individuals born small for gestational age have increased risks of serious illness as newborns and throughout life, including hypertension, cardiovascular disease, type 2 diabetes and pregnancy-related hypertension and diabetes. Both traditiona
Maternal-Fetal Conflict: The Effect of Imprinted Genes on Fetal Growth
Endothelial cells (EC) release several factors that reduce vascular tone and counteract vasoconstriction including nitric oxide (NO) and prostaglandin (PG) I2. In the rabbit aorta and mouse mesenteric artery, endothelium-dependent relaxations t
Eicosanoids, Vascular Tone and Blood Pressure
Description of Overall Purpose-The long-term goal of the proposed research is to further develop and understand the nitric oxide (NO) and nitroxyl (HNO), the one-electron reduced form of NO, producing reactions of C-nitroso compounds (1, Scheme
The Nitroxyl/Nitric Oxide Producing Reactions of Hyrozyurea and Related Compounds
The 90 kDa heat shock proteins are proving to be extraordinary cancer chemotherapeutic targets as evidenced by the fact that more than 20 clinical trials are currently in progress. Unfortunately, all of these trials are based upon N-terminal i
Development and Evaluation of Purine and Coumarin Based Hsp90 Inhibitors
Communication and Social Marketing to Promote Seasonal Emergent Influenza Immunization for Hispanics
NCHM Program Communications (ARRA line 11 old 145)
The contractor will provide scientific services to satisfy the epidemiologic objectives of the National Center for Immunization and Respiratory Diseases, Division of Viral Diseases (DVD), Epidemiology Branch (EB).  The primary objective is to p
Capital for loans to rural small businesses seeking to expand and create jobs for local residents.
LONE WOLF HISTORIC BRIDGE/PEDESTRIAN BRIDGE
CS Fr. ON STUART PL RD,FM 0.101 MI S BUS83 To. 0.070 MILES SOUTH OF US 83;  WIDEN TO 4 LANE
Pavement & Rehabilitation, South II-VII, 2009
CR 84 (BLUE RIDGE ROAD) I87 TO CR 25 - MILL & FILL
1R - WASHINGTON AVE RESURFACING PROJECT, CITY OF ALBANY
1R - RIVER RD/PROVIDENCE AVE RESURFACING PROJECT, SCHDY CO
SR 739 FROM US 41(S OF ALICO) TO SIX MILE CYPRESS PKWY
US 191 Safford Sidewalks, Discovery Park to Relations St
The long-term objective of the proposed project is to create a unique, state-of-the-art facility for bioengineering and biomedical research within the Fitzpatrick Center for Interdisciplinary Engineering, Medicine and Applied Sciences (CIEMAS).
Extramural Research Facilities Improvement Program - CIEMAS
CIP funding will allow for the physical renovation and upgraded equipment at UC Irvine's Family Health Centers (FHC) in Santa Ana and Anaheim.  This renovation with equipment procurement will allow for additional providers, increased access to
ARRA -- Capital Improvement Program (CIP)
Primary Health Network (PHN) will utilize Capital Improvement Program (CIP) funds for renovations at 10 existing practice sites which will improve each facility's ability to provide efficient, quality care for both existing and new patients.  H
Community Medical & Dental Care, Inc.(CMADC) provides primary and oral health care to more than 15,000 residents of Monsey, Spring Valley, and surrounding areas within Rockland County, NY.  Operating a two-site FQHC in Monsey and Spring Valley,
Hyndman Area Health Center, Inc. has a satellite clinic, HAHC-Bedford, located in the borough, and township of Bedford, PA. HAHC-Bedford has currently out grown its satellite location which is not expandable. HAHC Management and Board of Direct
Hyndman Area Health Center's - Bedford Renovation Project
CommuniCare Health Centers has two proposed projects for CIP funding:   1. Davis Community Clinic (DCC) Dental Operatory Renovation - This renovation project will convert an office space in the Davis Community Clinic's dental wing into a fourth
Funding from the Capital Improvement Program will help SJMCS develop and expand the capacity as part of a planned expansion needed to respond effectively to the increased demand within the community.  SJMCS. CIP proposal includes three componen
Mammalian genomes have a complex physical structure shaped by myriad duplications, deletions and rearrangements, and this structure varies considerably among the populations and individuals of a species. These 'structural variations' are of spe
Extent, Origin, and Control of Structural Variation in Mammalian Genomes
campaign. Outdoor advertising will be employed to deliver stark facts about American inequality in predominantly African American neighborhoods, thereby raising consciousness and minimizing negative health outcomes. Taken together, the propose
Intervention Racism, the HPA Axis, and African American Health
The Nurse Faculty Loan Program provides funds to eligible schools of nursing that offer advanced education nursing programs to prepare graduates to serve as faculty in a school of nursing. The schools use the funds to establish distinct NFLP fu
Osteoporosis, resulting from increased bone resorption relative to formation, affects millions of Americans and its prevalence is increasing with the aging population. It is estimated that half of all women over the age of 50 will have an osteo
Age-related cognitive decline has been documented across many species including rodents, non-human primates, and humans. Normal cognitive aging, while accompanied by structural preservation of the brain, represents a significant compromise of t
EPIGENETIC BASIS OF NORMAL COGNITIVE AGING
Globally, a large majority of HIV-1 infection in women occurs through heterosexual transmission (HST). HST transpires when semen (considered as the principal source for both cell-free (cf) and cell-associated (ca) virus) from an infected male i
THE ROLE OF SEMINAL AMYLOID FIBRILS IN HIV-1 TRANSMISSION ON CERVICAL MUCOSA
Articular cartilage damage is a growing problem with active and increasingly aging populations. Cartilage, which is critical for frictionless and painless joint motion, has little endogenous repair capability. Aging processes and trauma lead to
DEVELOPMENT OF A TISSUE-INTEGRATED HA-BINDING MATERIAL FOR CARTILAGE REGENERATION
Neisseria gonorrhoeae is the causative agent of gonorrhea; humans are their only natural host.  Neisseria can disseminate from mucosal surfaces to cause severe diseases.  Sexually transmitted infections, including gonorrhea, cause substantial m
TRANSCYTOSIS OF NEISSERIA GONORRHOEAE THROUGH T84 EPITHELIAL CELLS
The objective of the proposed project is to evaluate the cellular immune response to Rift Valley fever virus (RVFV) wild-type (ZH501) and vaccine strain (MP-12) infections. There is very little published data pertaining to the effect of RVFV in
CELLULAR IMMUNE RESPONSE TO RVFV INFECTION
Pruritus is the clinical term for itch, an unpleasant nocifensive sensation that results in the desire to scratch the affected area. Pruritus can greatly reduce the quality of life of those inflicted, and further consequences of pruritus can in
Endocannabinoid Modulation of Pruritus Fellow: Joel Schlosburg
Temporomandibular joint disorders (TMJD), including osteoarthritis and internal derangement, have a high prevalence in the adult population and often cause pain and limited jaw function. Severe deterioration of the articular cartilage of the ma
CARTILAGE SHAPING FOR BIOLOGICAL RESURFACING/REPLACEMENT OF THE TMJ
Streptococcus pneumoniae is a major cause of morbidity and mortality worldwide. The pneumococcus is able to colonize and replicate in a number of sites in the human host including the nasopharynx (colonization), lungs (pneumoniae), blood (sepsi
BACTERIAL CATION EXPORTERS: A NEW SIGNALING PARADIGM FOR BACTERIAL VIRULENCE
NLR Regulation of Innate Immune Responses to Respiratory Virus Infection Project Summary/Purpose: Innate immune responses to viruses and other pathogens typically involve a highly conserved host-cell signaling mechanism designed to protect and
NLR Regulation of Innate Immune Responses to Respiratory Virus Infection
The goals of this study are two-fold: 1) to understand how energy-dependent ATPase enzymes function in bacterial secretion and 2) to elucidate mechanisms of ATPase regulation by accessory proteins. This application will focus on characterizing
Defining AAA+ Enzyme Function in Bacterial Secretion
Both U.S. licensed influenza vaccines provide little heterosubtypic protection, and thus, must be reformulated annually in an attempt to match the vaccine strains with those circulating in subsequent epidemics. Thus, an ideal influenza vaccine
IMMUNE MECHANISMS OF CATIONIC LIPID-DNA COMPLEX ADJUVANT
Many bacterial pathogens utilize toxins to cause serious disease. For instance, anthrax lethal toxin (LeTx) is one of the primary virulence factors that Bacillus anthracis utilizes to subvert the host immune system and induce cell death, result
Identifying Host-Factors Required for Toxin Entry and Toxicity
Approaches to therapeutic intervention for food allergies include the prevention of food allergy and the treatment with immunotherapy for an individual with an established allergy [1]. In this proposal, both of these interventions will be devel
Prevention and Treatment of Cashew Allergy via Pepsinized Allergens
Malaria and other human diseases caused by mosquito-borne pathogens are major threats to global health. The spread of insecticide-resistant mosquitoes, drug-resistant parasites and the lack of effective or affordable vaccines have all led to an
Signaling Pathways that Regulate Juvenile Hormone Synthesis in Mosquitoes
This improvement request involves animal facility equipment purchase for the North Carolina State University (NCSU) College of Veterinary Medicine (CVM), specifically, individually ventilated cage systems for mice, and support equipment, for us
Improving Animal Resources at N.C. State University
The general objective of this project is to provide support and care for the use of pathogen free and genetically modified mice at Georgetown University.  This grant will purchase ventilated racks, perform minor renovations and install a wirele
This proposal outlines a plan for capacity building at the Rocky Mountain Regional Biocontainment Laboratory (RMRBL) at Colorado State University. The RMRBL is one component of the CSU Foothills Campus Infectious Disease Research Center (IDRC).
Biosecurity Enhancements for the Rocky Mountain Regional Biocontainment Laborator
SLRP is a collaborative effort among state and federal entities that offers physicians an opportunity to practice their profession in a community that lacks adequ
The applicant cannot keep up with the current demand for medical services, primarily due to a lack of providers in relationship to the health needs of patients. BMC currently operates with five 3-member medical clinic teams per day; each team c
Mattapan Community Health Center (MCHC) proposes to use the IDS funds to hire an internist by July 2009 to fill a previously vacant position and to meet the growing demands of the uninsured and the underinsured.  The health center also plans to
Preliminary Effectiveness Analysis of Universal Rotavirus Immunization, Nicaragua   The goal of the study is to measure the effectiveness of a universal rotavirus vaccine immunization program in reducing diarrhea in a developing world setting (
Effect of Rotavirus Immunization on Childhood Diarrhea in Nicaragua
This award provides for ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provision of Section 640(a)(5) of the Head Start Act for the Head Start and Early Head Start Program.  Head Start promotes the sc
The goal of this project is to identify functional variants of environmentally responsive genes that are biologically relevant to motor neuron degeneration of sporadic amyotrophic lateral sclerosis (SALS) and primary lateral sclerosis (PLS). Co
Environment-Sensitive Genes in Motoneuron Degeneration
The following grant application is submitted in response to RFA-OD-09-005 (Recovery Act Limited Competition: Supporting New Faculty Recruitment to Enhance Research Resources through Biomedical Research Core Centers [P30]). We believe that the a
To hire an indentified faculty candidate who will join an interactive and multidisciplinary gourp of researchers at MUSC who are currently investigating the plasticity of ascohol addiction and dependence.  The proposed new faculty hire will aug
Research Core Center--Neuroplasticity of Alcohol Addiction
This P30 proposal is in response to RFA-OD-09-005 and has the goal of hiring an early stage investigator with a strong record of research productivity and interests and expertise in alcohol research of a developmental nature as a tenure-track,
ARRA:Faculty recruitment for alcohol researcher, Binghamton University
The loss of cognitive function with normal aging is well known and while clearly different from the catastrophic loss of memory seen in Alzheimer's disease and the other age-related dementias, is of concern to an increasing number of Americans.
Faculty recruitment on the Neurobiology of Aging
The purpose of this proposal is to recruit two faculty members to the Musculoskeletal Research Consortium program at the University of Michigan. The new faculty will be part of an innovative multidisciplinary program focused on the interface be
FACULTY RECRUITMENT TO MUSCULOSKELETAL RESEARCH CONSORTIUM
The UAB Comprehensive Cancer Center is the hub for cancer research activities at UAB and requests funding from the NCI through this mechanism to facilitate recruitment of two early stage investigators as part of the Center's membership. In part
UAB COMPREHENSIVE CANCER CENTER EARLY STAGE INVESTIGATOR RECRUITMENT
The major goal of the Division of Hematology at the University of Washington is to recruit and support physician/scientists to facilitate our mission of bi-directional translational research.  Dr. Eli Estey, Professor of Medicine/Hematology, ha
Recruitment of a translational researcher for leukemia
This award is for the recruitment of junior faculty who will be involved in melanoma research and will serve to expand an initiative in melanoma disase focused basic and translational research at Case Comprehensive Cancer Center.  Funds will su
New Faculty Recruitment to Enhance Melanoma Research
A critical enhancement to the Core Center for Systems Biology and Cancer at the Cancer Institute of New Jersey funded by this proposal will be a New Investigator who is an experimentalist with experience in uncovering the biological consequence
Core Center for Systems Biology and Cancer: Supporting New Faculty Recruitment
The nascent interdisciplinary field of Neuroeconomics harnesses the computational rigor of economics and the technological advances of modern biology to advance discovery in the decision sciences. Since pathologies of decision making are endemi
DESCRIPTION: Increasing evidence suggests that disturbances in attention and working memory may contribute to the development of specific language impairment (SLI) and stuttering. However, how a detriment in these functions interacts with both
Electrophysiological Indices of Attention in Language Processing
The Department of Physiology and Membrane Biology is applying for P30 funds to recruit new faculty with research focus and demonstrated achievement in the areas of membrane transporter, channel or receptor structure function analysis and or mod
Recruitment into the UC Davis School of Medicine Membrane Biology Initiative
This application seeks support from the National Heart, Lung & Blood Institute (NHLBI) through the NIH P30 mechanism (OD-09-005) for resources to recruit a newly independent assistant professor to the Diabetic Cardiovascular Disease Center (DCD
FACULTY RECRUIT FOR WASHINGTON UNIVERSITY DIABETIC CARDIOVASCULAR DISEASE CENTER
This award is being used for a physician-scientist, who joined the faculty on July 1, 2010 to expand the focus of the laboratories of airway biology within the Division of Pulmonary, Allergy, Critical Care, and Sleep Medicine at the University
NEWLY INDEPENDENT FACULTY RECRUITMENT AND SUPPORT FOR PULMONARY RESEARCH
The goal of this proposal is to provide funds for start-up packages for two new, independent tenure-track faculty members in the Department of Neurobiology and Behavior at SUNY Stony Brook. Support would be utilized to revitalize the faculty se
ARRA: Recruitment of Two Tenure-Track Faculty to Neurobiology & Behavior, Stony Brook
These are exciting yet challenging times for Dartmouth Medical School (DMS), as we strive to recruit and nurture junior-level faculty to thrive in and perpetuate Dartmouth's rich tradition of excellence in biomedical research and education. The
Recruiting Faculty in Neurophysiology of Channels, Synapses and Circuits Research
Dartmouth Medical School Dept. of Physiology
The Aim of the Program Plan that is the basis of this application is to expand the breadth of research expertise and research programs in the Center for Pain Research at the University of Pittsburgh.  Center faculty members have identified two
Pittsburgh Center for Pain Research Recruitment of a New Faculty Member
Brandeis University is home to 22 neuroscience research laboratories and is a rich and collaborative environment for neuroscience research. However, a gap exists between cellular and molecular neuroscientists using mainly in vitro techniques, a
Imaging Neural Circuit Activity in the Mammalian Central Nervous System
Impact: This P30 will unfreeze a new faculty recruitment to enhance resources through a Biomedical Research Core Center in Neural Engineering at Penn State University. The impact will be the ability to hire a powerful and unique candidate in a
INNOVATIONS AT THE INTERSECTION OF NEURAL ENGINEERING, MATERIALS SCI & MEDICINE
Preliminary data on proteins secreted by adipose tissue in the obese with high BP (OHBP) and obese with normal BP (ONBP) indicate a pro-inflammatory profile in OHBP (lower adiponectin, higher interleukin 6, higher plasminogen activator inhibito
Inflammation and Injury in Obesity Hypertension in African American Adolescents
Potential method to reduce alcohol-related problems, including various types of crime, is to decrease overall drinking rates by changing environmental factors such as the availability of alcohol. Our goal is to evaluate whether density of alcoh
Assessing Density of Alcohol Outlets, other Outlets and Crime
Alcoholic liver disease affects more than 2.5 million people and costs in excess of $1.5 billion/year for treatment and lost productivity in the U.S.. Alcohol use remains the most common cause of liver-related mortality. Worldwide, alcoholic li
Mechanisms of In Vivo Ethanol-Induced Mitochondrial Depolarization
Alcoholism and anxiety frequently co-occur in humans; however, it has been difficult to find a single treatment which is effective against both conditions. Substantial evidence suggests that the motivational aspects of alcohol withdrawal (e.g.,
Anxiety and Alcoholism: Novel BenzodiazepineTreatments
drinking level, with genetic variability originating from familial-risk for alcoholism minimized. As ERPs also are sensitive to tobacco smoking status, subjects who have never smoked will be compared to individuals who smoke daily for each bin
Alcohol and Tobacco CNS Effects in Binge Drinkers
Despite our ability to identify risk factors that may increase the likelihood of acquiring Alzheimer's (such as age, family history, and some possible genetic markers), we cannot identify with certainty those who will develop this disease. A re
Natural History of Amyloid Deposition in Adults with Down Syndrome
Elderly patients who suffer traumatic brain injury (TBI) have increased mortality and survivors have a poorer prognosis than young or middle aged adults who suffer comparable injuries. We have demonstrated that the aging brain is in a hyperinfl
Inflammation and traumatic brain injury in the elderly
The proposed studies of this application will explore the essential process of accurate transcription initiation in trypanosomatid parasites which cause major human diseases. The proteins involved in this process exhibit an unprecedented diverg
TRYPANOSOME CLASS II TRANSCRIPTION PRE-INITIATION COMPLEX
Streptococcus pneumoniae (S.p.), an important human pathogen causing pneumonia, is a major cause of morbidity and mortality worldwide. Its early mortality rate still remains the highest when compared to the pre-antibiotic era. Pneumolysin (PLY)
REGULATION OF HOST RESPONSE IN S. PNEUMONIAE INFECTIONS
This project is to define the defect in T cell positive selection Themis (previously known as MG143) knockout mice in terms of signaling pathways that are affected, the interactions with other members of the TCR-signaling cascade, and changes i
A Novel Protein Regulating Thymocyte Development
Multidrug resistant (MDR) tuberculosis (TB) is recognized as an emerging infectious disease and a major problem in global public health. MDR M. tuberculosis is also classified as a Category C Priority Pathogen for biodefense research.  The thre
Mycobacterial Siderophores: Assembly, Assembly Inhibition, and Role in Virulence
Research Grant entitled 'Salmonella Genes Associated with Colonization of Specific Hosts'. The purpose of this research is to identify salmonella genes responsible for the colonization of specific host species.
Salmonella Genes associated with Colonization of Specific Hosts
Pathogens have developed sophisticated mechanisms to enter cells, evade destruction inside the eukaryotic cell and multiply. The cytoskeleton of the host cell is a common target that is manipulated by bacteria to facilitate infection. Invasive
Defects in the appropriate regulation of T cell function and homeostasis are fundamental to the pathogenesis of Systemic Lupus Erythematosus (SLE). Classically, SLE exhibits a striking gender bias and preferentially affects women. Although sex
Cross-Talk Between Estrogen and T Cells Mediated Pathways in Lupus Pathogenesis
The magnitude and the duration of cytokine action are essential in determining the response to foreign antigens and allergens. Thus, the action of cytokines is tightly regulated both developmentally and within the cell. The Suppressor of Cytoki
The goal of this proposal is to elucidate the molecular mechanisms that control lineage-specific expression or repression of the Ifng locus as a model for understanding factors regulating effector T cell lineage specification.  Th1, Th2, and Th
CONTROL OF CHROMATIN LANDSCAPES IN EFFECTOR T CELL LINEAGE SPECIFICATIONS
The envelope of Gram-negative bacteria consists of two membranes separated by the periplasmic compartment that contains the peptidoglycan wall. The inner membrane (IM) is in contact with the cytosol while the outer membrane (OM) contacts the ex
Transport and Insertion of Outer Membrane Proteins
The COPS Hiring Recovery Program(CHRP)provides funding directly to law enforcement agencies to hire and/or rehire career law enforcement officers in an effort to create and preserve jobs, and to increase thei community policing capacity and cri
To upgrade Hawaii County Prosecutors Office server environment to improve ability and efficiency in handling case information. Fund 2 evidence specialist and purchase 2 digital camers for the Hawaii County Police Department.
Law Enforcement Planning and Research Director's Forum
Law Enforcement Organization of Planing  and Research Directors
Hammond Police Departemnt & Corrections Center Upgrade
To purchase tactical gear and misc. equipment
BJA FY 09 Edward Byrne Memorial Justice Assistance Grant Program: Local Solicitation
Grant funds will be used to upgrade office equipment.
NATIVE WOMEN'S SOCIETY OF THE GREAT PLAINS RECLAIMING OUR SACREDNESS
The grant funded the position of the public education specialist of the Native Women's Society of the Great Plains, who has provided onsite training, technical assistance and assisted in developing educational campaign plans to ten targeted mem
Native Women's Society of the Great Plains
The goal of this project is to expand the on-going work of ODVN through training and technical assistance to member programs and collaboration with state agencies regarding economic issues facing survivors of domestic violence.  The objectives
WASHINGTON STATE COALITION AGAINST DOMESTIC VIOLENCE
Grants to State Sexual Assault and Domestic Violence Coalitions: Preserve .5 FTE Legal Advocacy Program Coordinator position; Provide technical assistance and training to legal advocates and civil legal services providers; Stimulate economic re
OVW Recovery Act Grants to State Sexual and Domestic Violence Coalitions Program, U.S. Department of Justice, Office on Violence Against Women
CONNECTICUT COALITION AGANIST DOMESTIC VIOLENCE
Through the Engaging Others Project, the Connecticut Coalition Against Domestic Violence (CCADV) has three distinct areas of work within the grant period. First, CCADV will enhance the skills and knowledge of domestic violence advocates; will e
The emphasis of the Violence Against Women 2009 Recovery Act Program is centered upon the creation of jobs, the preservation of jobs and the promotion of economic stimulus.  As one of its many elements, the Recovery Act provides states with gra
Thanks to a one year extension, we are enjoying the benefits of STOP ARRA funds in a variety of ways through April 30, 2012.  The required 5% for the Courts, in addition to judicial training, has been used primarily for an initiative intended t
The Recovery Act STOP supports communities in their efforts to hire and retain criminal justice and victim services personnel that respond to violent crimes against women as a way to develop and strengthen effective law enforcement, prosecution
The Recovery STOP Violence Against Women Formula Grant is for initiatives to reduce crimes of domestic violence, sexual assault, dating violence and stalking. The STOP (Services, Training, Officers and Prosecution) Program supports communities
Recovery STOP Violence Against Women Recovery Formula Grant for the State of Maine
The ARRA VAWA funds will be used to strengthen victim services programs, including sexual assault, domestic violence and dating violence programs, provide funds for specialized domestic violence prosecutors, provide funding for domestic violenc
OVW Recovery Act STOP Violence Against Women Formula Grant Program.
Washington State Recovery Act STOP Violence Against Women Formula Grant.
Washington State Recovery Act STOP Violence Against Women Formula Grant
Legislative Building416 Sid Snyder Avenue S.W.
The STOP Violence Against Women Formula Grant program under the Act assists states in improving both the criminal justice system response to violence against women and services available to women victims.  The Office of Justice Assistance (OJA)
Wisconsin STOP Violence Act Recovery Act
PUBLIC SAFETY, MASSACHUSETTS EXECUTIVE OFFICE OF
The Violence Against Women Act (VAWA) STOP grants promote a coordinated, multidisciplinary approach to enhance services and advocacy to victims; improve the criminal justice system's response; and promote effective law enforcement, prosecution,
The La Jolla Band of Luiseno Indians has 720 community members who could be served under this project, including Tribal and non-Tribal members living on the Reservation.  The Tribe will address challenges including: 1) lack of understanding abo
This project provides transitional housing assistance for victims of domestic violence, sexual assault and stalking.  The project also offers support services for the victims.
Transitional Housing Assistance for Victims of Domestic Violence, Dating Violence, Sexual Assault or Stalking
The Recovery Act Tribal Grants Program supports Tribes in their efforts to hire and retain criminal justice and victim services personnel that respond to violents crimes against women as a way to develop and strengthen effective law enforcement
House of Ruth's Transitional Housing Assistance Project will increase the availability of transitional housing for victims of domestic violence by providing housing assistance in the form of rental subsidies and move-in assistance.  The project
The three year project will benefit 12-18 families who are homeless or in need of transitional housing or transitional assistance due to domestic violence, dating violence, sexual assault, or stalking and emergency shelter services or other cri
Susan B. Anthony Project Recovery Act Transitional Housing Assistance Program
Recovery Act Transitional Housing grant provides the necessary funding for  victims of domestic violence who reside in Rose Brooks Center's Transitional Housing Program to receive specialized support services in employment counseling along with
Rose Brooks Center's Transitional Housing Program
This project will allow the Abused Adult Resource Center to further assist victims of domestic violence, dating violence, stalking and sexual assault in locating and securing permanent housing as well as integrating into their communities.
This grant will support the recipients efforts in promoting economic recovery by empowering victim advocates and other personnel to assist victims of domestic violence, dating violence, sexual assault and stalking who are in need of transitiona
OVW Recovery Act Transitional Housing Assistance Grants for Victims of
The purpose of this grant is to increase options for Latinas experiencing domestic violence through increased access to culturally relevant transitional housing, employment and supportive services.
Increasing Access to Transitional Housing for Latina Victims of Domestic Violence
The Transitional Housing Assistance Program was reauthorized and amended on January 5, 2006 by the Violence Against Women Act of 2005 (VAWA 2005).Transitional Housing Assistance Program grant funds must be used to support programs that; a)provi
Overcoming Barriers to Independence and Safety Through Transitional Housing and Employment Supports
The Transitional Housing and Stabilization Services Project will serve rural Madison County, Kentucky. Madison County Kentucky holds the cities of Richmond and Berea, and is located in the southern portion of Appalachia. This program will provi
Recovery Act Transitional Housing and Stabilization Services
YOUNG WOMEN'S CHRISTIAN ASSOCIATION OF WESTERN MASSACHUSETTS
Supportive Housing Program for Victims of Domestic Violence, Stalking and/or Sexual Assault
NORTH CAROLINA COALITION AGAINST SEXUAL ASSAULT INC
To create a management level position to enhance the capacity of our agency and response to member rape crisis centers.
Invasive aspergillosis caused primarily by Aspergillus fumigates is an emerging source of morbidity and mortality in developed countries including the U.S.  Despite the accumulating evidence of the medical significance of this common mold, our
Host-Pathogen Interactions in Invasive Aspergillosis
Tolerance to allogeneic grafts can be achieved in a number of rodent models, and long-term graft survival has been reported in a number of non-human primate models. A consistent feature of stable graft acceptance is the control of alloantibody
An urgent need exists to prevent the sexual transmission of HIV-1 to women. Although infection rates exceed 35% in parts of sub-Saharan Africa, very little attention is devoted to the role of the female reproductive tract (FRT) in preventing vi
Hormone Regulation of Human Anti-HIV Molecules in the Female Reproductive Tract
The association of Clq with autoimmune diseases in genera!, and with systemic lupus erythematosus (SLE) in particular, has been firmly established. Genetic deficiency of Clq is in 3L? fact considered to be a strong susceptibility factor for SLE
ARRA:  The Role of C 1 q in Regulation of Monocyte to Dendtritic Cell Transition
DESCRIPTION (provided by applicant): CD4 T cells are an essential component of the immune responses against HIV and other virus, but CD4 T cells are the prime targets for HIV infection.  Hence, there are concerns that HIV vaccines which stimula
CC Chemokine Secretion to Protect Antigen-Specific CD4 T Cells fom HIV
The long-term goal of this project is to identify novel monoclonal antibodies (mAbs) that broadly recognize the HIV-1 envelope glycoprotein (Env) and block infection in vitro to guide vaccine development. This goal will be pursued in a cohort o
Broad Neutralizing Monoclonal Antibodies From HIV Controllers
Pathogenic bacteria require iron for their survival and ability to cause infection. Heme comprises 90% of the iron available within the host and plays a significant role in the colonization and virulence of many bacterial pathogens. Shigella sp
Structure-Function of the Shigella dysenteriae heme uptake operon (shu)
A mechanistic understanding of cancer rests heavily upon the mutated genes. Mutated genes include the dominant oncogenes and recessive suppressor genes that are mutated somatically to drive tumorigenesis. Pancreatic cancer has historically been
HIGH-THROUGHPUT ANALYSIS OF PANCREATIC CANCER MUTATIONS
Melanoma, the most virulent form of skin cancer, is not responsive to chemotherapy. This project proposes to develop a method to sensitize melanomas to chemotherapy by selectively acidifying the cancer cells whileminimally affecting normal cell
NMR of Melanoma Acidification, Bioenergetics, Metabolism and Therapeutic Response
The selective expression of vascular endothelial growth factor (VEGF) receptors on surface of tumor vessel endothelial cells (ECs) is an attractive target for radiotherapy. We propose to use a genetically engineered form of VEGF-A (VEGF121) lab
SCVEGF TARGETED RADIOTHERAPY OF MAMMARY AND COLONIC CANCER
In this proposal, we build upon an epidemiologic risk model for lung cancer that we recently developed from a lung cancer case-control study of 1851 Caucasian lung cancer patients and 2001 controls, matched to the cases on sex, age (15 years),
The public health implications of reliable risk prediction tools for estimating the probability of lung cancer, the leading cause of cancer mortality in the US, are immense. In this proposal, we build upon an epidemiologic risk model for lung c
We previously discovered that a protein called CYP24 is over-produced in lung cancer. The purpose of this award is to determine the role of CYP24 in stimulating the development and/or growth of lung tumors. CYP24 degrades the natural anti-tumor
Role of CYP24 in Non-Small Cell Lung Cancer
DESCRIPTION (provided by applicant): Radioresistance markedly impairs the efficacy of radiotherapy and involves cell signal transduction pathways that prevent radiation-induced cell death. Proteins in the Bcl-2 family are central and dual regul
Molecular cancer radiosensitization by targeting Mcl-1
We propose to conduct a genome-wide association study to identify loci involved in endometrial cancer causation. We plan to utilize studies with available biospecimens, 6 cohorts from the NCI Cohort Consortium and 7 case-control studies, within
Genome Wide Association Study of Endometrial Cancer
Our overarching goals are to design better therapies for the treatment of brain tumors. Medulloblastoma, a pediatric malignancy of the cerebellum with the highest incidence of all pediatric brain tumors, and glioma, the  most malignant and inva
Inhibitors of Hedgehog Signaling For Brain Cancer Chemotherapy
This proposal focuses on the design and development of a scalable PET detector with depth-of-interaction (DOI) positioning capability.  The basic module design will be suitable for high resolution, small animal PET imaging and clinical, time-of
A Scalable, Monolithic, DOI, TOF, MR compatible, PET Detector
DESCRIPTION (provided by applicant): Uveal melanoma is a rare malignancy of the eye. Survival rates are poor. Metastatic disease occurs frequently and invariably results in death. At present there is insufficient evidence to support the use of
In contrast to the well studied role of intrinsic factors in tumorigenesis, knowledge regarding the mechanism(s) whereby extrinsic factors, such as the stromal/matrix microenvironment, influence an initiated cell with permanent genetic alterati
OSTEOPONTIN AND MICROENVIRONMENT OF INITIATED CELLS
Ultraviolet (UV) radiation represents a definitive risk factor for skin cancer, particularly in combination with certain underlying genetic traits, such as red hair and fair skin. Skin pigmentation results from the synthesis of melanin in pigme
The role of pheomelanin in cutaneous melanoma
The sansalvamide A (San A) scaffold is a promising structure for the development of novel cancer therapeutics. We have used the San A scaffold to produce 7 compounds that are cytotoxic to pancreatic and colon cancer cell lines at nanomolar conc
Conformational Based Design and Development of Antitumor Agents
Cigarette smoking is the single most important preventable cause of morbidity, mortality and excess health care costs in the United States and accounts for 30% of U.S. cancer deaths. Varenicline and bupropion SR (sustained-release) are non nico
Combination Therapy with Varenicline and Bupropion for Smoking Cessation.
1. Instrument development:  We will design and implement new coherence imaging instrumentation to enable examination of colorectal tissues for ex vivo studies.  For the a/LCI surveillance studies, we will develop new fiber optic probe designs s
COHERENCE IMAGING FOR ASSESSING COLORECTAL NEOPLASIA
Specific Aims are to determine: (1) The mechanistic basis of Pak1 stimulation by DSB damage and role of Pak1 in DSB signaling in breast cancer cells; (2) The molecular basis and significance of MORC2’s contribution in DNA damage response
Role of PAK1-MORC2 Pathway in Breast Cancer
The Role of MicroRNA Alterations in Barrett?s Carcinogenesis: Patients with Barrett?s esophagus (BE) are at increased risk of developing esophageal adenocarcinoma (EAC), one of the most rapidly increasing cancers in developed nations. The molec
THE ROLE OF MICRORNA ALTERATIONS IN BARRETT'S CARCINOGENESIS
The intent of this research is to gain knowledge about how to maximize drug use prevention effectiveness under real-world conditions. This research will address the question: 'What can be done to make prevention programs more effective once the
The Impact of Adaptation on Successful Implementation
Addiction to cocaine and other illicit drugs is estimated to cost our society $181 billion which equates to $603 per U.S. citizen. The cost of addiction can be dramatically lowered through the use of treatments; unfortunately, many drugs of abu
TARGETING SYSTEM XC- FOR THE TREATMENT OF ADDICTION
To determine in a laboratory model of CM, using money as a non-drug alternative, whether: a) higher vs. lower magnitude continuous positive reinforcement increases cocaine elasticity; b) intermittent positive reinforcement conditions differenti
HUMAN LABORATORY MODEL OF COCAINE TREATMENT BEHAVIORAL ECOMOMIC ANALYSIS
Opioid abuse and dependence are growing public health problems in the United States. While rates of heroin use have remained fairly stable over the past several years, abuse and dependence on prescription opioids have shown sharp increases over
New Neural Targets for Opioid Use Disorders: Human Studies
The human sweet receptor, composed of the monomers T1R2 + T1R3, appears to be the main (and perhaps the only) receptor underlying sweet taste in humans. When co-expressed with a reporter G-protein in heterologous systems, this heterodimeric rec
AGONIST & ANTAGONIST ACTIVITY AND BINDING ON THE TMD OF HT1R3
How multimodal stimuli become integrated is a fundamental question in neuroscience. This question is particularly relevant to flavor perception, in which simultaneous stimulation of touch, temperature, taste and olfaction invariably occurs duri
Multimodal flavor integration and retronasal olfaction in the rat.
Dental progenitor cells are a unique stem cell resource for tissue repair and regeneration because of their accessibility and because of the autologous potential of tissues derived from third molar teeth.  The current proposal is based on the h
Epigenetics of Dental Stem Cells Markers and CP27 Function
It is the long-term objective of this study to understand the genetic control of root development and periodontium formation. Advances in molecular and developmental biology have linked the function of numerous genes to specific stages of organ
Molecular Regulation of periodontium Formation
Our general goal is to determine the temporal and spatial interactions among lipolytic proteins in adipocytes and myocytes. The goal will be accomplished by 2 specific aims: 1. To test specific mechanisms of lipase, co-activator and scaffold in
ANALYSIS OF LIPOLYTIC TRAFFICKING IN ADIPOCYTES
Autosomal dominant polycystic kidney disease (ADPKD) is largely caused by mutations in the PKD1 and PKD2 genes, encoding the polycystins 1 (PC1) and 2 (PC2) proteins. The pathogenesis of ADPKD entails dysfunctional ion transport and/or regulato
Micro- and macrovascular disease are major causes of morbidity and premature mortality in diabetes mellitus. Our underlying hypothesis is that vascular damage is promoted by the inter-related proceses of dyslipoproteinemia, inflammation, and ox
Lipoproteins and PEDF in the Vascular Complications of Diabetes
he overall goal of this project is to determine the role of oxidative stress with associated inflammation and abnormalities in nitric oxide synthase (NOS) in the pathogenesis of clinical cardiovascular disease (CVD), carotid IMT, cardiac MRI an
Biomarkers for Complications in Type 1 Diabetes (DCCT/EDIC)
The serine proteases are the pivotal regulators of a variety of cellular processes critical for normal homeostasis. In the gut, host intestinal serine proteases not only control digestion, but their unregulated activities contribute to the path
Protease Pathways in the Gastrointestinal Tract
Obesity is a major independent risk factor for type 2 diabetes mellitus (T2DM), obesity promotes chronic macrophage-mediated adipose tissue inflammation, resulting in increased release of free fatty acids from adipocytes and ectopic accumulatio
TPL2: A CENTRAL NODE IN OBESITY-ASSOCIATED INFLAMMATION AND METABOLIC DISORDERS
Recent evidence implicates cilia abnormalities as important in the etiology of Polycystic Kidney Disease. Our laboratory has defined an important role for polarity proteins, such as the apical transmembrane protein Crumbs3, in ciliogenesis. In
MOTIVIATION - One of MRI?s inherent biophysical contrast parameters is proton self-diffusion, which can be measured by diffusion-weighted imaging (DWI). A variant, Diffusion Tensor Imaging (DTI), is an MRI method for noninvasive quantitative ma
Novel Acquisition Methods for Diffusion MRI
Lung disease is the third leading cause of mortality in the United States, has an economic impact of over $154 billion (USD) a year and in its chronic form impacts the lives of over 35 million Americans. Interstitial lung disease (ILD), which i
Regional Assessment of the Lung Using Magnetic Resonance Elastography (MRE)
Prostate cancer is the most common male cancer, claiming almost 27,000 lives annually.1 One of the treatment options for localized prostate cancer is surgery?radical prostatectomy, which is performed in 70,000 patients every year in United Stat
REAL-TIME MULTIPHOTON MICROSCOPY OF PERIPROSTATIC TISSUE ARCHITECTURE FOR IMPROVING SURGICAL OUTCOMES DURING NERVE-SPARING RADICAL PROSTATECTOMY
DESCRIPTION (provided by applicant): Autoimmune and allergic diseases afflict millions of people worldwide. Novel immunosuppressive strategies to prevent and treat these diseases are urgently needed. Following several years of studying the pote
THE AHR AS A NOVEL PATHWAY FOR THE INDUCTION OF REGULATORY T CELLS
Endocrine disrupting compounds (EDCs) are hormonally active, synthetic or natural chemicals that interfere with normal functioning of the endocrine system. Exposure to EDCs continues to be a significant and contentious public health issue. Beca
ENDOCRINE DISRUPTORS AND FETAL DEVELOPMENT
HSV-1 virus infection of the cornea is a leading cause of infectious blindness. Corneal damage results from virus-induced inflammation of the cornea. These studies will address the role that corneal anti-inflammatory proteins play during herpet
The Role of Apoptotic Molecules in Herpetic Stromal
The purpose of this research grant is to explore the relationship between visual skills and reading using rigorous scientific methods in school settings.  Students in grades 3-5 will be assessed for visual skills (convergence, divergence, accom
Civil Rights, Social Action & Advocacy, General/Other
We previously described a naturally occurring mutation (Nuc1) in the Sprague-Dawley rat with a novel and unusual eye phenotype. Nuc1 is inherited as a single Mendelian locus with viable homozygotes and an intermediate phenotype in heterozygotes
A CRYSTALLIN MUTATION WITH ABNORMAL ASTROCYTES AND RETINAL VESSELS
The neural crest is a vertebrate innovation, sometimes referred to as the fourth germ layer; the neural crest gives rise to migrating cells that differentiate into cartilage, melanocytes, the peripheral nervous system, and the outflow tract of
NFkB Targets and Neural Crest Development
ParA systems play an important role in chromosome segregation and are responsible for the segregation of many bacterial plasmids.  This proposal focuses on the ParA partitioning system of E. coli plasmid F, which consists of the SopA (ParA) ATP
CYTOLOGY AND FUNCTION OF PARA IN E. COLI
) of intracellular Ca2+ signals help to specify which Ca2+-dependent effectors are triggered by a particular physiological stimulus. G protein-coupled receptors (GPCRs) provide one primary means of regulating VDCCs and the Ca2+ signals they gen
G PROTEIN-MEDIATED REGULATION OF CALCIUM CHANNELS
Mass spectrometry is one of the most important tools for proteomics. Especially important are new protocols recently implemented for the identification of low- concentration analytes in the presence of very large backgrounds. NEMS-based mass s
SINGLE-MOLECULE MASS SPECTROMETRY ENABLED BY NANOMECHANICAL SYSTEMS (NEMS-MS)
Human embryonic stem cells (ESCs) and induced pluripotent stem cells (IPSCs) can only be used effectively in recipients with the same (or nearly the same) histocompatibility type, to avoid rejection or toxic immunosuppression.  To overcome this
Derivation and Transplantation of Histocompatible Pluripotent Stem Cells
A-synuclein (aSyn) is an intrinsically disordered protein that appears in aggregated form in the brains of patients with Parkinson's disease. The conversion of monomer to aggregate is complex. Aggregation rates of aSyn are very sensitive to cha
Experiments & Computations to Find Aggregation-Prone Ensembles of Alpha-Synuclein
Many species of bacteria swim using flagella, which consist of thin helical filaments turned by rotary motors in the cell membrane. Assembly of the bacterial flagellum depends on a specialized secretion apparatus at the base that exports the pr
MECHANISM OF FLAGELLAR TYPE-III SECRETION
As a whole, mitochondrial diseases are among the most common hereditary diseases. They can arise from mutations of nuclear or mitochondrial (mtDNA) genes that encode for components of the oxidative phosphorylation (OXPHOS) machinery. It is clea
Modulation of Oxidative phosphorylation by mitochondrial soluble adenylyl cyclase
Neglect affects large numbers of children each year and its negative health, social, emotional and academic consequences to children are well documented. Despite this, there has been little theoretical or empirical work identifying its causes.
MATERNAL INTELLIGENCE, SOCIAL INFORMATION PROCESSING  AND NEGLECT
We are interested in understanding transcriptional regulation during early oogenesis, specifically the post-mitotic stages, and the transition from prenatal to postnatal ovary, when clusters of oocytes begin to form into primordial follicles. E
LIM HOMEODOMAIN REGULATED GENETIC PATHWAYS IN OOGENESIS AND OVARIAN FAILURE
Role of ?-Tubulin Mutations in Lissencephaly.  The purpose of this award is to characterize mutations in ?-tubulin that cause lissencephaly, with a view to developing approaches that might ameliorate the effect of these mutations. Lissencephaly
Role of ?-Tubulin Mutations in Lissencephaly
CENTER FOR CULTURAL AND TECHNICAL INTERCHANGE BETWEEN EAST AND WEST, INC.
5R03HD45508-2, PI: Retherford) that expired November 30, 2007.  	Public health relevance: The fertility of a population is an important aspect of public health. In this grant application, fertility is measured by the total fertility rate and i
Multivariate analysis of the total fertility rate and its components
This project makes publicly available via ICPSR an existing longitudinal individual-level database, the Liaoning Multi-Generational Panel (LMGP), that comprises 1.3 million triennial observations of more than 230,000 residents of approximately
MULTI-GENERATION FAMILY AND LIFE HISTORY PANEL DATASET
ARRA - Genetic by Context Influence on Trajectories of Adolescent Aggression 1R01HD057222-01A1 The overall purpose of our study is to gain a greater understanding of how the family and peer context of adolescents can buffer or exacerbate geneti
ARRA - Genetic by context influence on trajectories of adolescent aggression
Being born a girl or boy carries implications for physical and psychological health and illness. Considerable scientific and public interest is focused on the development and maintenance of these sex-related processes, but there are noticeable
GENDER DEVELOPMENT IN EARLY ADOLESCENCE PRENATAL HORMONES  & FAMILY SOCIALIZATION
HIV/AIDS continues to be a critical public health problem in the United States and men's heterosexual behavior plays a key role; 83% of women with HIV/AIDS are infected through sex with men. Among men who have sex with women (MSW), homeless men
Heterosexual HIV Risk Behavior in Homeless Men
Human pluripotent stem cells (hPSCs) will be crucial for the development of regenerative therapies, especially when autologous specialized cells cannot be obtained in sufficient quantity. Despite great promise, pluripotent embryonic stem (ES) c
Pluripotency of Amniotic Fluid-Derived Stem Cells
The development of the limb relies on reciprocal signaling between celln exists concerning the mechanisms of development to enable the majority of these defects to be detected or prevented pre-natally. An important goal is to develop animal mod
Role of Ectodermal Signals in Limb Bud Outgrowth and Development
The experiments proposed in this study were designed to investigate the role played by the phosphatidylinositol 3-kinase (PI3K) signaling pathways mediating leptin action on reproduction. These studies were proposed to better understand the rol
Role of Leptin-Mediated P13 Kinase Signaling on Reproductive Control - ARRA Stimulus 2 Yr Funding
Vitamin E was discovered in 1922 as a lipid soluble factor necessary for reproduction and named 1-tocopherol from the Greek words for 'birth' and 'to carry'. To date, a-tocopherol's role in reproduction has been impossible to approach experimen
MECHANISMS OF VITAMIN E FUNCTION STUDIED IN ZEBRAFISH
The project attempts to provide MRI correlates to the described minicolumnopathy of autism.  In this regard available postmortem MRI (both autistic and controls) will be examined for gyral window measurements and correlated to computerized imag
Gross morphological correlates to the minicolumnopathy of autism
Arterial baroreceptors (BR) are essential for reliable neural control of heart rate and blood pressure. The data quantifying the properties of these pressoreceptors and the reflexogenic consequences of BR function and dysfunction are extensive.
ARRA, Neuromechanical basis of baroreceptor function
The broad objective of this new application is to advance our understanding of the pathophysiological mechanisms of human Cardiorenal Syndrome (CRS) with a specific emphasis upon the biological interaction between diuretic therapy, the renin-an
Our tissue engineering approach to heart muscle regeneration combines heart cells with a biodegradable polymer template (scaffold) in a laboratory culture device (bioreactor) to create a contractile heart muscle graft. Such tissue engineered ca
Rational Design of a Cardiac Tissue Engineering Scaffold
This project tests a hypothesis that activation of the endoplasmic reticulum stress-related signaling pathways is a mechanism by which apolipoproteins (fats that combine with proteins for transport in the blood) in ApoE-deficient lipoprotein mi
Endoplasmic reticulum stress and foam cell formation
The long-term goal of this research initiative remains to delineate the cytoprotective role of proinflammatory cytokines in myocardial ischemia reperfusion (I/R) injury. We previously made the observation that the cytoprotective effects of tumo
CYTOPROTECTIVE CYTOKINE SIGNALING AND REPERFUSION INJURY
Ischemic reperfusion (I/R) is known to trigger an increase of reactive oxygen species in the myocardium. Although high levels of oxidants can cause damages, low doses of oxidant elicit a protective effect, such as during preconditioning induced
Translational Control of Oxidative Stress in Myocardial Infarction
Endothelial response to fluid shear stress has been strongly implicated as a key factor in the focal development of atherosclerotic lesions in human arteries. The hypothesis of this grant is that the glycocalyx plays a pivotal role in the trans
The Role of Glycocalyx in Mechanotransduction
In response to changing afferent input, neural pathways may undergo both short term (minutes) and long term (days, weeks) adjustments within the pathway in order to maintain physiological output within an appropriate range. The underlying cellu
Mechanism of Homeostatic Plasticity in a Visceral Sensory Circuit.
Evidence-based guidelines for asthma management have been available to practicing physicians since 1991.1 Randomized controlled clinical trials have demonstrated that implementation of asthma guideline recommendations can significantly improve
IMPLEMENTATION OF ASTHMA GUIDELINES IN PRIMARY CARE; COMPARISON OF 4 APPROACHES
Severe sepsis is a systemic response to infection that culminates in acute organ failure. Preclinical models of sepsis demonstrate that a disturbed microvasculature characterized by hyporesponsive vessels and heterogeneous flow contributes to o
Mechanisms and Meanings of Impaired Microvascular Responses in Human Sepsis
Cardiac valve thickening is a major cardiovascular manifestation of connective tissue disorders (e.g., Marfan syndrome (MFS) and Ehlers-Danlos syndrome (EDS)), and non-syndromic valvular diseases. In humans POSTN protein is reduced in pediatric
Regulation of Periostin by TGFbeta and BMP in Heart Development.
Macrophages are the most prominent cell type in atherosclerotic lesions, and are associated with three hallmarks of the disease:lipid deposition, inflammation, and macrophage-derived foam cell disordered apoptosis. The ability to regulate SMS a
ARRA: The Effect of Macrophage Sphingomyelin Synthase (SNS) on Atherosclerosis
CONNECTICUT SEXUAL ASSAULT CRISIS SERVICES, INC
The goal of the current project is to enhance and strengthen comprehensive, coordinated, and culturally appropriate services to sexual assault victims and their families. Accomplishment of this goal will be supported through one main objective:
The OVW Recovery Act statewide sexual assault coalitions provide direct support to member rape crisis centers through funding, training and technical assistance, public awareness activities, and public advocacy (e,g, state coalitions might work
MINNESOTA COALITION AGAINST SEXUAL ASSAULT
This project will develop and implement a train the trainer program for sexual assault advocacy trainers across Minnesota. The staff to be hired will research training best practices, evaluate current Minnesota advocacy training programs, gathe
Sexual Assault Advocacy Training and Supervision Project
NEW HAMPSHIRE COALITION AGAINST DOMESTIC & SEXUAL VIOLENCE
This award will support the state coalition's efforts in promoting economic recovery, and preserving and creating jobs that coordinate victim services and resources to their state.
Grants to State Sexual Assault and Domestic Vionece Coalition-Recovery Act Stimulus Funding
Economic Justice Program.  The Vermont Network proposes to use funds to support its Economic Empowerment Project.  The Economic Empowerment Project seeks to improve the economic well-being of victims in Vermont by building the capacity of membe
The Title of this program is: DOJ-0VW Recovery Act Grants to State Sexual Assault and Domestic Violence Coalitions Program. Coordinadora Paz para La Mujer (Peace for Women Coordinator) is the Puerto Rico Coalition against Domestic Violence and
Puerto Rico Coalition Against Domestic Violence and Sexual Assault
The District of Columbia American Recovery and Reinvestment Act supplemental funding for the Community Services Block Grant (CSBG) program allocates funds to CSBG sub-recipients to support economic and employment related activities in the areas
To make grants to States, Territories, Tribes, and tribal organizations for child care assistance for low-income families and to: (1) allow each State maximum flexibility in developing child care programs and policies that best suit the needs o
The ARRA funds will be used to upgrade the carpet in our food distribution center; to upgrade our computer; and to replace our 16 year old van.
White Earth Food Distribution was awarded a contract through the United States Department of Agriculture to renovate the existing office building, construct a garage, and to purchase a generator, a truck with a plow and a lawn tractor.
Food Distribution Program on Indian Reservations (FDPIR)
rican Recovery and Reinvestment Act Port Security Grant Program
BOARD OF TRUSTEES OF THE GALVESTON WHARVES, THE
American Recovery and Reinvestment Act for Port Security Grant Program
DEPARTMENT OF EMERGENCY SERVICES AND PUBLIC PROTECTION
for costs related to enhancing the Nation's port and maritime infrastructure to prevent, protect, respond to, and recover from threats or acts of terrorism. These funds are intended to create a sustainable, risk-based effort for the protection
Recovery and Reinvestment Act Port Security Grant Program (ARRA PSGP)
PLAQUEMINES PORT HARBOR & TERMINAL DISTRICT
ARRA Port Security Grant; award was less than request, do not which project(s) will receive support
American Recovery and Reinvestment Act Port Security Grant Progrma (ARRA PSGP)
ARRA Port Security Grant Program for costs related to enhancing the Nation's port and maritime infrastructure to prevent, protect, respond to, and recover from threats or acts of terrorism.
American Recover and Reinvestment Act Port Security Grant Program 9ARRA PSGP)
Investment A: Port Security Grant received for two investments: (1) design and construction of a Command and Control Center for $1 million; and Investment B: $725,000 to purchase a hazardous materials response vehicle
American Recovery and Reinvestment Act - Port Security Grant Program - (ARRA PSGP) - Delaware River Infrastructure Protection Project
American Recovery and Reinvestment Act - Port Security Grant Program - (ARRA PSGP) - Delaware River INfrastructure Protection Project
American Recovery and Reinvestment Act Port Security Grant Program (ARRA PSGP)include the following three projects: 1) Joint Marine Division Security Capabilities enhancement Project. 2) Redundant Deployable Trunked Radio System Project. 3)Fore
PORT OF TEXAS CITY SECURITY COUNCIL, INC.
ARRA PSGP Award for the Port of Texas City Security Council
GREATER CLEVELAND REGIONAL TRANSIT AUTHORITY
AMERICAN RECOVERY AND REINVESTMENT ACT TRANSIT SECURITY GRANT PROGRAM - LAW ENFORCEMENT.
The COPS Hiring Recovery Program funding is being used to hire fifty (50) new police officers to the Milwaukee Police Department. The additional police officers will aid the Milwaukee Police Department in sustaining its public safety initiative
The COPS Hiring Recovery Program (CHRP) provides funding directly to law enforcement agencies to hireand/or rehire career law enforcement officers in an effort to create and preserve jobs, and to increase thier community policing efforts
The COPS Hiring Recovery Program (CHRP) provides funding directly to law enforcement agencies to hrie and/or rehire career law enforcement officers in an effort to create and preserve jobs.
THE COPS HIRING RECOVERY PROGRAM (CHRP) PROVIDES FUNDING DIRECTLEY TO LAW ENFORCMENT OFFICERS IN AN EFFORT TO CREATE AND PRESERVE JOBS, AND TO INCREASE THIER COMMUNITY POLICING CAPACITY AND CRIME PREVENTION EFFORTS.
The COPS Hiring Recovery Program (CHRP) provides funding directly to law enforcement agencies to hire and/or rehire career law enforcement personnel.  We have amended the grant to 2 officer rehires.
The COPS Hiring Recovery Program (CHRP) is funded through the American Recovery and Reinvestment Act(Recovery Act) and provides funding directly to law enforcement agencies to hire career law enforcement officers in an effort to create jobs and
The 'COPS Hiring and Recovery Program (CHRP)' provided funding directly to law enforcement agencies to hire and/or rehire career law enforcement officers.
COPS Hiring Recovery Program (CHRP) - The City of Hemet's Sworn Officer Recovery Project was able to retain/rehire four sworn police officers that would have been laid off without the funds.
The COPS Hiring Recovery Program (CHRP) provides funding directly to law enforcement agencies to hire new and/or rehire career law enforcement officers in an effort to create and preserve jobs, and to increase their community policing capacity
The COPS Hiring Recovery Program (CHRP) provides funding directly to law enforcement agencies to hire and/or rehire career law enforcement officers in an effort to create and preserve jobs, and to increase their community policing capactiy and
The COPS Hirining Recovery Program (CHRP) provides funding directly to law enforcement agencies to hire and/or rehire career law enforcement officers in an effort to create and preserve jobs, and to increase their community policing capacity an
The aim of this proposal is to establish zebrafish (Danio rerio) models suitable for in vivo studies of certain processes of atherogenesis. It is widely accepted that hypercholesterolemia leads to lipid accumulation in arteries, which in turn i
ZEBRAFISH MODELS OF VASCULAR INFLAMMATION AND ATHEROSCLEROSIS
THIS PROJECT WILL TEXT THE FOLLOWING WORKING HYPOTHESIS. THE ACTIVITY OF THE HIGH AFFINITY PDE7 LOWERS CAMP LEVELS AND INCREASES BARRIER PERMEABILITY OF PULMONARY ARTERIAL ENDOTHELIAL CELLS. THE FOLLOWING SPECIFIC AIMS OUTLINE A PLAN TO TEST TH
CAMP PHOSPHODIESTERASE AND LUNG ENDOTHELIAL CELL PERMEABILITY
Nanomedicine approaches to atherosclerotic disease could have significant impact on the practice and outcomes of cardiovascular medicine. With recent concerns about the use of gadolinium and its relationship to Nephrogenic Systemic Fibrosis (NS
COLLOIDAL IRON-OXIDE NANOBEACONS FOR THERANOSTIC USE IN ATHEROSCLEROSIS
Worldwide, survival in HIV-infected patients has remarkably improved with the use of highly active anti- retroviral therapy (HAART); however, survival in HIV-infected patients remains decreased compared to the general population in part due to
Inflammatory Mechanisms and Treatment Strategies for Atherosclerosis in HIV
Heart transplantation is often the only available therapeutic option in end-stage heart disease. To monitor graft survival, recipients endure frequent invasive endomyocardial biopsies which carry a significant risk of complication and are prone
Cardiovascular disease is the leading cause of death in developed countries. Individuals with obesity, metabolic syndrome, and/or diabetes are at markedly increased risk of atherosclerotic cardiovascular disease although the underlying mechanis
Role of Serum Amyloid A in Atheroscierosis
Literature and Data Driven Hypothesis Generation for High Throughput Experiments Microarray gene expression analyses are used widely in biomedical research today. Thousands of genes can be assayed in a single experiment, and differences in thei
LITERATURE AND DATA DRIVEN HYPOTHESIS GENERATION FOR HIGH THROUGHPUT EXPERIMENTS
Rare diseases are studied in isolated laboratories, forgotten by main stream pharmacological companies, and considered almost academic curiosities. Finding variables that correlate/cause rare diseases (a condition is rare when it affects less t
Integrated discovery and hypothesis testing of new associations in rare diseases
Cyclic AMP (cAMP), the prototypical second messenger, regulates a wide variety of cellular processes. In the nervous system, cAMP has a role in many of the medium- to long-term changes that occur in neurons, and that we associate with higher-or
Resolution of Membrane Localized cAMP Signals in Neurons
Sensory information reaching the brain is processed by region-restricted neural networks leading to learning and adaptation to a constantly changing environment. Recent studies have elucidated some of the general molecular mechanisms underlying
The Role of GRP and GRPergic Circuitry in Fear Memory
Epigenetic Marks as Peripheral Biomarkers of Autism  Autism spectrum disorders (ASD) are a common phenotype with a complex etiology. While a rare single gene or genomic interval may be sufficient to lead to ASD, most patients likely owe their d
EPIGENETIC MARKS AS PERIPHERAL BIOMARKERS OF AUTISM
Acute respiratory failure is a heterogeneous disorder that results in more than 300,000 Americans requiring admission to an intensive care unit for invasive mechanical ventilatory support each year. Though acute respiratory failure is a pulmona
The Diagnosis and Treatment of Critical Illness Polyneuromyopathy in Patients wit
Glucocorticoids (GCs), the adrenal steroids secreted during stress, can compromise the ability of neurons to survive necrotic neurological insults. These deleterious effects have often been viewed as counterbalanced by the benefits of the anti-
Pro-inflammatory glucocorticoid effects in the CNS
This new, revised R01 application is based on the success in achieving the goals of a previous R21 award, i.e. the creation of a 'striatal-specific' transgenic mouse model of Huntington's disease. In brief, this mouse model, demonstrates medium
Despite significant progress in stroke prevention and its acute treatment, stroke remains the third leading cause of death and the leading cause of adult morbidity worldwide. Fundamental advances in stroke will require collecting and pooling ad
The sphingolipid storage diseases are a group of ~40 genetically distinct disorders that result from inherited deficiencies of lysosomal hydrolytic activities or lipid transport. Among this group is Niemann-Pick type C disease, an autosomal rec
Unraveling mechanisms of Niemann-Pick C neuropathology with mouse models
Purpose: to examine deficits in planning movements, specifically task switching, due to Parkinson's disease (PD).  Task switching is the ability to make a change in the plan (switching from one response option to another, e.g. pressing one butt
Subproject for Institution # 08-004048:  Neural Substrates of Switching in Parkinson's Disease
Glutamate-mediated excitotoxicity is believed to be involved in the pathogenesis of many neurological disorders, such as amyotrophic lateral sclerosis (ALS) and Alzheimer's disease (AD). Excitotoxicity is defined as excessive exposure to the ne
(ARRA) Translational regulation of glutamate transporter EAAT2 & therapeutic application
Nicotinic receptors have been implicated in a broad range of neurological disorders including Alzheimer?s disease (AD), Schizophrenia, Autism, Frontal Lobe Epilepsy,Parkinson?s disease, Tourette Syndrome and Attention Deficit Disorder. Given th
NOVEL, SUBTYPE SELECTIVE POTENTIATORS OF NICOTINIC ACETYCHOLINE RECEPTORS
Insults to the brain and spinal cord result not only in debilitating motor, sensory and cognitive deficits, but also in chronic, excruciating and relentless pain that is largely resistant to treatment. In most patients, pain starts weeks or mon
Maladaptive plasticity following spinal cord injury
The goal of this proposal is to elucidate the role of the p42/44 mitogen-activated protein kinase (MAPK) pathway as a regulator excitotoxic cell death and aberrant structural remodeling in the hippocampus. Traumatic brain injury-induced cell de
(ARRA) Mechanisms of hippocampal excitotoxic cell death and structural remodeling
Studies of familial Alzheimer's disease (AD) have revealed three important AD genes, Amyloid Precursor Protein (APP), Presenilin 1 PS1) and Presenilin 2 (PS2), in which mutations lead to autosomal dominant AD with nearly complete penetrance. Re
Impact of Presenilin 2 Mutation and Deficiency on Microglial Function
DESCRIPTION (provided by applicant): This project aims to build on the existing retirement literature within economics by using a unique combination of administrative data, quasi-experimental variation and structural estimation to analyze the l
USING POLICY VARIATION TO IDENTIFY AND ESTIMATE A STRUCTURAL MODEL OF RETIREMENT
Burkholderia (B.) mallei is a highly evolved Gram-negative bacterium that primarily infects solipeds but it is transmissible to humans by ingestion, cutaneous or aerosol exposures. Concern over this bacterium and the very closely related specie
Burkholderia:  Characterizing Lunc Innate Immunity
This project investigates the role of beta-arrestin 1 and 2 as negative regulators of inflammatory response in collagen-induced arthritis. Understanding beta-arrestin 1 and 2 expression in correlation to the disease severity, its cellular speci
The Role of Beta-Arrestins 1 and 2 in Rheumatoid Arthritis
Culture and Identification of Rickettsia-like Organisms in Maryland: the specific aims of this project are to 1) use shell-vial culture techniques to culture/isolate known and unknown Rickettsia-like organisms from man-biting ticks of Maryland
CULTURE AND IDENTIFICATION OF RICKETTSIA-LIKE ORGANISMS IN MARYLAND
ARRA Methyltransferase Inhibition Assay Development
Human cytomegalovirus is the major infectious cause of birth defects in the United States. We recently found that two current candidate vaccines fail to elicit high levels of antibodies that block viral entry into epithelial cells. Based on the
Guinea pig cytomegalovirus as a model for vaccines that target endocytic entry
The broad, long range objective is to understand molecular mechanisms that regulate initiation of skeletal muscle (skm) atrophy. The objective of this application is to explore the role of Merg1a in initiation of skm atrophy. The central hypoth
Role of Merg1, a K+ Channel in the Onset of Skeletal Muscle Atrophy
Although osteoporosis affects more than 2 million men in the United States today and nearly 12 million more have osteopenia, low bone mass often goes undiagnosed and inadequately treated in males (Wright 2006).  The overall goal of the proposed
Efficacy of Plyometrics to Increase Bone Mass in Men
In surgical education, an apprenticeship model has long been traditional. However, this model is increasingly being challenged due to the rapid development of increasingly complex and minimally- invasive procedures that are associated with stee
Does simulator training improve arthroscopy skills in orthopedic residents?
Dietary Intake Patterns of N-Nitroso Compounds
This study will explore the relationship between reported tobacco use and presence/amount of cotinine (an objective biomarker of smoking) in existing specimens linked to a large, widely available dataset often used for epidemiologic research, i
Accuracy of Self-Reported Prenatal Smoking in Child Cancer Epidemiology Studies
Head and neck cancers (HNSCC) are the fifth most common malignancy worldwide. Human papillomavirus (HPV) infection has recently been identified as an etiologic agent for development of a subgroup of HNSCC (i.e., oral-pharyngeal cancers) with up
Curcumin, a naturally occurring dietary polyphenol, has shown significant potential as a chemopreventive in cell culture models of breast cancer. However, curcumin suffers from poor oral bioavailability in vivo, resulting in sub-optimal systemi
Sustained Release Curcumin Microspheres for Breast Cancer Chemoprevention
Co-occurrent substance use and violence compromises the health, safety, well-being, and life chances for adolescents. Although research has identified important risk and protective factors for substance use and violence independently, less is k
Correlates of the Co-Occurrence of Violence and Substance Use Among Boston Youth
This present project proposes a quantitative examination of the factors that impact program completion among a population of students in the first campus drug court program in the U.S. called Back on TRAC (BOT). The BOT program addresses a grow
Individual, Social and Eduational Predictors of Program Completion for College St
Opioids such as morphine are the most effective treatment for pain. Unfortunately, this opioid analgesia is limited by the development of tolerance with repeated administration. Cannabinoids also have been shown to have analgesic effects, but t
Neural Mechanisms for Enhanced Cannabinoid/Opioid Antinocicaption
The current project is a B-Start grant that is being used to collect preliminary data to submit a R01. Specifically, hallucinogens are generally considered to be physiologically safe (i.e., they do not result in physiological dependence nor do
The impact that drug addictions have on health disparities impacting at-risk African Americans who reside in the rural South are grossly understudied. While there is strong evidence linking drug use and abuse to violent behaviors, injuries, men
Stress and Drug Use Vulnerability in Rural African Americans
065 River's Crossing; 850 College Station Rd.
Otitis media (OM) is the most common childhood bacterial infection and also the leading cause of conductive hearing loss in children. Inflammation in the middle ear caused by microorganisms is a hallmark of OM. Nontypeable Haemophilus influenza
REGULATION OF INFLAMMATION BY EGFR IN OTITIS MEDIA
Temporomandibular joint disorders (TMDs) are an important national health problem affecting more than 10 million people in the United States. Although the exact cause of TMDs is unclear, the temporomandibular joint (TMJ) disc pathophysiology (i
Biophysical Modeling of Fluid and Solute Transfport in the TMJ Disc
Overall Purpose: This proposal focuses on development of a new approach for regenerating natural bone tissues, with emphasis on developing injectable hybrid microparticles providing osteoconductivity, osteoinductivity and structural integrity i
Dual release of osteogenic factors to enhance bone regeneration
Radiological exposure from a terror event has been identified by the CDC and the Office of Homeland Security as a potential threat worthy of significant national preparedness. Little research has been done, however, to develop risk communicatio
Developing Radiological Risk Communication Materials for Low-Literacy Populations
Despite aggressive public education campaigns, maternal tobacco smoking remains an important public health problem. Our murine model of gestational maternal smoking demonstrates significant alveolarization abnormalities, including fewer alveoli
Maternal Smoking and the Developing Lung
The award will focus on a common but poorly understood disease of the human female reproductive tract, uterine leiomyomas.  Our preliminary findings deomonstrate that leiomyomas alter their molecular expression patterns to decrease retinoic aci
Molecular Dissection of Retinoic Acid Function in Leiomyoma Development
Non-motile, primary cilia are found on the surface of a strikingly diverse range of cell types and play critical roles in development and disease, including polycystic kidney disease, hydrocephalus, syndromic obesity, and retinal degeneration.
ROLE OF CILIARY PROTEINS IN ENDOTHELIAL CELLS MORPHOGENESIS
This project will investigate the influence of mastery motivation climate physical eduction programming on physical activity in rural african American children (ages 5-8) who are risk for poor health.  The long term goal is to provide school ag
Exploring Physical Activity Response to Motivational climates in african American Children
This pilot study will examine the adverse influence of prenatal and postnatal exposure to intimate partner violence (IPV: male violence toward their female partners) on one year old infants' emotional and physiological [i.e., hypothalamic-pitui
EFFECTS OF PRE- AND POSTNATAL IPV ON INFANT BEHAVIOR AND PHYSIOLOGY
Our project will consider an alternative and previously-overlooked explanation: that children born throughout the year are not initially similar but are conceived by women with different socioeconomic characteristics. To consider this alternati
Season of Birth and Later Outcomes: Old Questions, New Answers
Aggression and victimization are both risk factors for social-psychological adjustment problems and future psychopathology. The study of the developmental course of aggression and victimization among children is crucial for identifying children
ARRA: Relational aggression, victimization, and adjustment during middle childhood
Research has consistently shown that children's eating and weight status are strongly influenced by parental feeding styles and practices. Because it is infeasible to randomize naturalistic behaviors, data that relate feeding practices to child
New Methods for Estimating Effects of Parenting on Child Eating and Overweight
In the United States, 20.8 million people (7% of the population) suffer from diabetes. About 75% of all newly diagnosed cases of type I diabetes occurs in individuals younger than 18 years of age. Type 1 diabetes is a chronic autoimmune diseas
PREVENTION OF DIABETES BY PDNA ENCODED WITH IL-10
DESCRIPTION (provided by applicant): Intrauterine growth restriction is a significant cause of fetal and neonatal mortality and morbidity and is major health-related problems in the U.S. Growth-restricted infants that survive the neonatal perio
UNDERNUTRITION IN PREGNANCY AND DEVELOPMENTAL PROGRAMMING OF VASCULAR FUNCTION
Airway inflammation, airway remodeling, colonization with microorganisms, and parenchymal destruction are hallmarks of chronic obstructive pulmonary disease (COPD). In addition to cigarette smoking, infectious pathogens likely contribute to the
Pneumocystis jirovecii and macrophages in COPD
Idiopathic pulmonary fibrosis (IPF) is a progressive interstitial lung disease of unknown etiology, characterized by scaring in the lung and impaired pulmonary function. The pathogenetic mechanisms leading to IPF are poorly understood, and ther
Expression of Heparan Sulfate 6-0 Endosulfatases In Idiopathic Pulmonary Fibrosis
Department of Medicine - Pulmonary Diseases
Voltage-sensitive potassium (Kv) channels are proteins that exist in the membranes of all electrically excitable cell types. Kv1.4 (the mammalian homologue of Shaker) and all Kv4 (Shal-type) subunits generate potassium-selective current phenot
ARRA: Kv4.3 Gating Current: Mechanisms Underlying Closed State Inactivation
Glioblastoma (GB) is the most common type of brain tumor and is usually rapidly fatal. Clinical trials indicate that treatment with temozolomide (TMZ) coupled with chemotherapy is beneficial to patients. Unfortunately, only a small number of pa
ROLE OF PROMOTOR POLYMORPHISMS OF THE MFMG GENE IN ALKYLATION CHEMOTHERAPY.
Every year, thousands of humans suffer traumatic brain injury (TBI) and most of the survivors manifest moderate to severe neurological dysfunction. Currently no known therapies that can prevent secondary neuronal death and/or promote neurologic
ARRA PPAR-gamma as a therapeutic target after TBI
The long-range goal of this project is to generate a fluorescence-based microarray diagnostic platform and a rugged device capable of reading DNA and/or protein microarrays for performing the routine array-based comprehensive DNA, protein, path
Demographic Analysis of SES Stability & Well-Being Among Children of Immigrants
The transcription factor MRF4 is an important regulator of numerous other genes involved in the development, growth, and regeneration of skeletal muscle cells.  Elucidating the mechanisms that regulate MRF4 gene transcription should improve our
MRF4 Expression and Regulation in Xenopus
WWAMI Lab Integrated Science Building Room 226
Cilia are complex and essential cellular machines that propel fluid over cells and sense stimuli in the environment. Recent discoveries about the central role that ciliary defects play in many human diseases and birth defects have energized the
Roles of Cilia and Mechanisms of Ciliogenesis in Animal Development
The long-term objective of this proposal is to understand the genetic and hormonal mechanisms controlling gonad development in vertebrates.  Primary sex determination in most vertebrates results in the development of a single gonad, ovary or te
This National Institutes of Health AREA award will permit novel research at Whitman College in the area of developmental neurobiology. The proposed studies characterize the relationship between glial cells and synapse development. There is a di
Glia as a source of signals for neuron development
This research project, “Phenotype analysis of tyrosine hydroxylase neurons in rat and human cortices,” explores the neurochemical phenotype of a subset of cortical interneurons in rats and humans. Understanding the phenotypic diversity of c
Phenotype analysis of tyrosine hydroxylase neurons in rat and human cortices
Asymptomatic gonococcal cervicitis is the primary factor contributing to the prevalence of gonorrhea in the general population as well as in the chronic disease sequelae observed, disproportionately, among women. That gonococcal disease in wome
Complement and hormone receptor modulation during gonococcal cervical infection
Tuberculosis remains a major health problem throughout the world, and development of vaccine is the most effective measure to control tuberculosis epidemic. Understanding the interactions between Mycobacterium tuberculosis (pathogen) and humans
Effect of ESAT-6 on human T cell immune function
Fetal alcohol exposure in humans is recognized as a likely contributor to alcohol abuse during adolescence and adulthood. Exposure to ethanol in laboratory rodents during the first two postnatal weeks is widely used as an experimental model of
ARRA: Ontogenetic changes in ethanol's motivational properties:Involvement of kapp
The pilot research project will examine the empirical validity of key assumptions regarding the epidemiology of adolescent alcohol use that underlie current federal and state policies toward community- based prevention of alcohol use and other
EXAMINING KEY ASSUMPTIONS: PREVENTION OF ALCOHOL USE
Women who abuse alcohol are twice as likely to develop anxiety disorders compared with men, a phenomenon in which the underlying biological mechanisms are unknown.  Our overall objective is to identify the interactive effects of alcohol and est
Interactive effects of ethanol and estrogen on brain vasopressin during puberty
A Feasibility Study to Improve Older Patient - Physician Communication The purpose of this study is to evaluate the feasibility of implementing a novel health information technology during routine outpatient encounters between physicians and ol
A Feasibility Study to Improve Older Patient - Physician Communication
The overall goal of this project is to conduct a longitudinal investigation of the incidence of medically serious (sentinel) adverse medical events among older adults and to examine subsequent patterns of health, healthcare service use, and cos
Investigation of Longitudinal Consequences of Adverse Events among Older Adults
The focus of this project is to develop the formative structures and processes needed to test the efficacy of hand feeding versus tube feeding in persons with late-stage dementia through a larger randomized controlled R01 study. Feeding among p
Feeding in Elderly Late-Stage Dementia: The FIELD Trial
This research seeks to determine the role extracellular matrix (ECM) plays in the aging of skeletal muscle. The loss of skeletal muscle mass and strength that occurs during the aging process represents a major health issue facing a growing elde
The role of ageing on the regulatory effects of skeletal muscle ECM…
We propose this exploratory project to investigate the underlying mechanism of osteoporotic vertebral fracture that is frequently observed in postmenopausal women. Osteoporosis is a metabolic bone disorder, predominantly prevalent in the elderl
(ARRA) Viscoelastic deformation of bone matrix in postmenopause
There is a need to quantify cellular turnover in the context of aging. We will establish the foundations of a new method to contribute crucial information to fulfill this need. This method will permit to track stable-isotope labeled cells and t
Cell fate and tissue turnover in the aged studied with multi-isotope imaging mass
Foxp3, a 47-kDa transcription factor, is necessary and sufficient for development and function of natural Tregs. The role of Foxp3+ Tregs in controlling self-reactive T cells and preventing autoimmunity is well established. During comparison of
PROTEOLYTIC CLEAVAGE REGULATES FOXP3 ACTIVITY
The COPS Hiring Recovery Program (CHRP) provides funding directly to law enforcement agencies to hire and/or hire career law enforcement officers in an effort to create and preserve jobs and to increase their community policing capacity and cri
The COPS Hiring Recovery Program (CHRP)provides funding directly to law enforcement agencies to hire career law enforcement agencies and preserve jobs, and to increase their community policing capacity and crime prevention efforts.
'The COPS Hiring Recovery Program (CHRP)provides funding directly to law enforcement agencies to hire and/or rehire career law enforcement officers in an effort to create and preserve jobs, and increase their community policing capacity and cri
The COPS Hiring Recovery Program  (CHRP) provides funding directly to law enforcement agencies to hire and/rehire career law enforcement officers in an effort to create and preserve jobs, and to increase their community policing capacity and cr
A ARRA Community Policing Grant for three deputies to address the law enforcement needs of St. Helena Parish and directed at drug interdiction.
Working closely with the community partners to develop problem solving skills and crime prevention measures remain the primary focus of the North Adams Police Department overall policing strategy. This grant has enabled the department to provid
The CHRP provides funding directly to law enforcement agencies to create and preserve jobs, and to increase their community policing capacity and crime-prevention efforts.
The COPS Hiring Recovery Program (CHRP) provides funding directly to law enforcement agencies to hire and/or rehire career law enforcement officers in an effort to creat and preserve jobs and to increase their community policing capacity and cr
DEPARTMENT OF PUBLIC SAFTEY- FISCAL AFFAIRS SECTION
The COPS Hiring Recovery Program (CHRP) provides funding directly to the Department of Public Safety to hire career law enforcement officers in an effort to create and preserve jobs and to increase their community policing capacity and crime pr
The cop's hiring recovery program provides funding directly to law enforcement agencies to hire and or rehire career law enforcement officers.
The COPS Hiring Rocovery Program provides funding directly to law enforcement agencies to hire and/or rehire career law enforcement officers in an effort to create and preserve jobs, and to increase their community policing capacity and crime p
The COPS Hiring Recovery Program (CHRP) provides funding directly to law enforcement agencies to hire anf/or rehire career law enforcement officers in an effort to create and preserve jobs and to increase their community policing capacity and c
'The COPS Hiring Recovery Program (CHRP) provides funding directly to law enforcement agencies to hire and/or rehire career law enforcement officers in an effort to create and preserve jobs, and to increase their capacity and crime prevention e
The COPS Hiring Recovry Program (CHRP) provides funding directly to law enforcment agencies to hire and or re-hire career minded police officers.
The COPS Recovery Hiring Program provides funding directly to law enforcement agencies to hire and/or rehire career law enforcement officers in an effort to create and preserve jobs, and to increase their community policing capacity and crime p
COPS ARRA Hiring:  The agency will enhance its COP initiatives by dedicating 2 experienced officers to reorient our focus on property and nuisance crime with an objective of increasing the # of property crimes investigated by 50% and increasing
COPS Grant = Community Oriented Policing Services
TO FUND 1 FULL TIME OFFICER FOR THREE YEARS TO INCLUDE AL BENEFITS FOR COMMUNITY POLICING
The COPS hiring Recovery Program(CHRP) provides funding directly to Law Enforcement agencies to hire and /or rehire career Law Enforcement officers in an effort to create and preserve jobs and to increase their community policing capacity and c
'The COPS Hiring Recovery Program (CHRP) provides funding directly to the law enforcement agencies to hire and/or rehire career law enforcement officer in an effort to create and preserve jobs, and to increase their community policing capacity
The Cops Hiring Recovery Program (CHRP)provides funding directly to law enforcement agencies to hire and/or rehire career law enforcement officers in an effort to create and preserve jobs, and to increase their community policing capacity and c
'The COPS Hiring Recovery Program (CHRP) provides funding directly to law enforcement agencies to hire and/or rehire career law enforcement officers in an effort to create and preserve jobs,and to increase community policing capacity and crime
The COPS Hiring Recovery Program (CHRP) provides funding directly to law enforcement agencies to hire and/or rehire career law enforcement officers in an effort to create and preseve jobs, and to increas their community policing capacity and cr
The COPS Hiring Recovery Program (CHRP) provides funding directly to law enforcement agencys to rehire career law enforcement officers in an effort to create and preserve jobs and to increase crime prevention efforts.
The COPS Hiring Recovery Progran (CHRP) provides funding directly to law enforcement agencies to hire and/or rehire career law enforcement officers in an effort to create and preserve jobs, and to increase their community policing capacity and
The COPS Hiring Recovery Program (CHRP) provides funding directly to law enforcement agenices to hire and/or rehire career law enforcemnt officers in an effort to create and preserve jobs, and to increase their community policing capacity and c
The COPS Hiring Recovery Program (CHRP) provides funding directly to law enforcement agencies to hire and/or rehire career law enforcement officers in an effort to create and preserve jobs, and to increase thier community policing capacity and
'The COPS Hiring Recovery Program (CHRP) provides funding directly to law enforcement agencies to hire and/or rehire career la enforcement officers in an effort to create and preserve jobs, and to increase their community policing capacity and
'The Cops Hiring Recovery PrograM (CHRP)
City of Jackson Police Department 234 Institute Street
The COPS  Hiring recovery Program provides funding directly to law enforcement agencies to retain hire and/or rehire career law enforcement officers.
The COPS Hiring REcovery PRogram (CHRP)provides funding directly to law enforcement agencies to hire and/or rehire career law enforcement officers in an effort to creat and preserve jobs, and to increase their community policing capacity and cr
'The COPS Hiring Recovery Program (CHRP) Provides funding directly to law enforcement agencies to hire and/or rehire career law enforcement officers in an effort to create and preserve jobs, and to increase their community policing capacity and
The COPS Hiring Recovery Program (CHRP) provides funding directly to law enforcement agencies to hire and/or re-hire career law enforcement professionals.
'The COPS Hiring Recovery Program provides funding directly to law enforcement agencies to hire and/or rehire career law enforcement officers in an effort to create and preserve jobs, and to increase their community policing capcity and crime p
The COPS Hiring Recovery Program (CHRP) provides funding directly to law enforcement agencies to hireand/or rehire career law enforcement officers in an effort to create and preserve jobs, and to increase their community policing capacity and c
The COPS Hiring Program provides funding directly to law enforcement agencies to hire and rehire career law enforcement officers in an effort to create and preserce jobs and to increase thier community policing capacity and crime prevention eff
The COPS Hiring Recovery Program provides funding directly to Law Enforcement agencies to hire and/or rehire career law enforcement officers in an effort to create and preserve jobs and to increase thier community policing capacity and crime pr
The Nacogdoches County Sheriff's Office will utilize the grant to train and better equip officers within the law enforcement and correction divisions.
Law Enforcement Training & Equipment Project
The disparate jurisdictions of the county of Kent, Camden Town, Dover City, Harrington City, and Smyrna Town will share the Fiscal Year 2009 Recovery Act Justice Assistance Grant award in the amount of $390,329, with the Dover Police Department
Edward Byrne Recovery grant.  Operation Safe Sam designed to locate and apprehend on line child sex predators.
This research addresses an important public need, the protection of an estimated 10 million workers in the U.S. who rely heavily on their voice as a primary tool of trade. Evidence has been growing that occupational voice users, such as teacher
RESEARCH TOWARD OCCUPATIONAL SAFETY IN VOCALIZATION
The significance of a sound is encoded not only in the firing patterns distributed throughout the auditory system, but also by the internal and external state of the animal. In other words, the processing involves not only the auditory system b
STUDIES OF THE COCHLEAR NUCLEUS GRANULE CELL DOMAIN
We have begun with identifying cell surface markers expressed by otic progenitor cells.  To date, we have narrowed down the list of markers to 28, which we are systematically testing for robust expression on Pax2/Pax8/Dlx5-positive otic progeni
Since March, funds continue to maintain one graduate research assistant and one postdoctoral scholar. The purpose of the supplement was to increase the number of animals phenotyped for inner ear function and the number of specimens undergoing m
GENETIC BASIS FOR GRAVITY RECEPTOR DYSFUNCTION IN MICE
This project is for additional needed equipment to augment pursuit of our research activities along four specific aims of the parent grant. The long-term goal of this project is to determine how the structure and mechanical properties of human
EAR BIOMECHANICS FOR RESTORATION OF HEARING
(# ROl DC006938).  The primary aim of the supplement is to accelerate our new work with mouse models that complement and extend our studies on the effects of peripheral nerve cut on central gustatory pathways and circuits. The dependence of ta
Neural Plasticity in the Adult Gustatory System
is due to properties of the stereocilia membrane itself. Together, the experiments in this proposal will allow us to determine how lipids regulate transduction and adaptation.
We have recently demonstrated that new inner hair cells (IHCs) are generated in the mammalian organ of Corti following gene therapy. Specifically, the experiments involve in vivo inoculation of an adenovirus vector with the Atohl gene insert (M
Acoustic and electrical hearing after Atoh1 treatment
This award provides additional funding for 5R01DC008120-05. This additional funding is provided under the American Recovery and Reinvestment Act of 2009 (ARRA).  This award provides funds to develop tools to examine the coding of sound informat
Regulation of excitability in a sensory system by cellular and network components
There is an overwhelming body of evidence that links sarcopenia, the age-related changes in muscle size, strength, and function, to anatomical and physiological changes within motoneurons, nerve-muscle connections, and the muscles themselves. I
ARRA Aging, Exercise and Mechanisms of Altered Tongue Function SUPPLEMENT
The purpose of the parent project is to compare speech intervention methods for improving speech accuracy and speech intelligibility in children with Down Syndrome. In keeping with the NIDCD and broader NIH guidelines, the proposed supplement i
Treatment of Speech Disorders in Children with Down Syndrome
The hair cell, located in the inner ear, is an essential component of the hearing process. The actin cytoskeleton plays a major role in hair cell function, through both the actin filament bundle in the stereocilium and the actin web in the cuti
Biochemical consequences fo Deafness-causing actin mutations
procedure, conducting test sessions (18-24 mos; n=50) in rural areas in northern California.  Our second aim is to record substantial samples of the home language environment using the LENA speech analysis technology, which enables us to recor
Infant Speech Processing as Predictor of Language Disorder in English and Spanish
The overall goal of the proposed project is to identify the neurotransmitters and modulators involved in mediating vestibulo-autonomic synaptic interactions. The four aims address the chemoanatomy and synaptology of these vestibular projection
CHEMICAL ANATOMY AND SYNAPTOLOGY OF VESTIBULO-SYMPATHETIC PATHWAYS
Songbirds are the most easily studied of the few animal groups that learn to produce vocal signals for social communication as humans do. Among songbirds, our knowledge of the zebra finch is most advanced and provides the best developed model s
Auditory Processing and Memory for Complex Signals
Cortical processing of sensory information plays a critical role in sensory discrimination, object recognition and memory. Cortical sensory processing has been shown to be highly dynamic, with past experience, current context and expectations s
This CLIN supplement proposes four goals that extend studies outlined in the parent grant   'Effects of Asymmetric Hearing in Acoustic Listeners and Cochlear Implant Users'. The premise of the parent grant is that listening with just one ear se
EFFECTS OF ASYMMETRIC HEARING IN ACOUSTIC LISTENERS AND COCHLEAR IMPLANT USERS
This grant will upgrade the research equipment used to study the olfactory system's effects on human physiology and behavior, and also help stimulate the economy and create jobs by allowing purchases of the new equipment.
Molecular mechanisms of olfaction in mammals
The goal of this project is to assess the efficacy of a new treatment for hypophonia (decreased vocal loudness) associated with Parkinson's disease (PD). Current speech therapy strategies for hypophonia focus on increasing sound pressure level.
Use of External Cueing to Treat Hypophonia in Parkinson's Disease
DESCRIPTION (provided by applicant): These studies have direct relevance for improving our understanding of the developmental defects associated with Chd7 deficiency. Precise regulation of gene expression is critical for normal development of m
Developmental Mechanisms of the Chromodomain Gene Chd7
Little is known of the inflammatory mechanisms of chronic otitis media that lead to inner ear pathology. Therefore, the long-term goal of this research program is to identify and prevent the inflammatory processes by which chronic middle ear di
Inner Ear Impact of Chronic Middle Ear Inflammation
Cochlear outer hair cells enhance the sensitivity of mammalian hearing through active mechanical feedback powered by the membrane protein prestin. The long-term goal of our research efforts is to understand the mechanism by which prestin intera
BIOPHYSICAL BASIS OF ORGANIZATION AND DYNAMICS OF PRESTIN MEMBRANE COMPLEXES
The primary purpose of the supplementary award was to accelerate our research applying MRI imaging technology to investigate the pathological correlates of tinnitus in an animal model. The second purpose of the supplement was to significantly u
Features of Chronic Tinnitus in an Animal Model as Indicated by MEMRI and MRS
This proposal presents a multidisciplinary approach to understanding a fundamental property of sensory processing: the modulation of sensory perception by acetylcholine. The proposal addresses this question in the olfactory bulb of rats, using
CRCNS: CHOLINERGIC REGULATION OF SENSORY COMPUTATION
We investigate the physiologic regulatory mechanisms for amelogenin expression during enamel formation. In situ hybridization of in vivo developing mouse incisors identified a periodicity for amelogenin transcript accumulation wherein one sagit
Determination and Expression of Amelogenin Gene Products
Fibroblast growth factor receptors (FGFRs) play essential roles in human development and metabolism.  The overall aim of this application is to understand how the activity of FGFRs is regulated and to unveil the mechanisms by which naturally oc
Mechanisms of FGF Receptor Regulaton and Signaling
This supplement will be used to expand Aim 2 of the parent grant by determining the mechanism underlying reorganization of ductal progenitors into ductal structures and elucidating the role of myosin II and tensile forces in the stabilization o
Regulation of SMG Development by Adhesion Receptors
The purpose of this administrative supplement is to support a new collaboration (subcontract with Dr. Michael Lovett at Washington University) to use the next-generation sequencing technologies to sequence  the entire genomic region containing
Understanding how apoptosis is regulated in salivary gland cells is critical for the development of therapeutics to protect salivary glands from irradiation induced damage and for the treatment of Sjogren's syndrome, salivary tumors and other d
The purpose of this administrative supplement is to recruit a highly skilled postdoctoral research scientist who will work on the creation of anatomically shaped human bone grafts for craniofacial repair. The researcher will focus on: (a) advan
This longitudinal study addresses the relationship between birth weight and early childhood caries (ECC) in a cohort of pre-term very low birth weight (VLBW) and full-term normal birth weight (NBW) infants. VLBW and ECC disproportionately affec
Longitudinal Study of Dental Caries in VLBW Infants
For this project supported by the Recovery Act we employed two student workers and allowed them to work on hands-on lab projects related to our parent grant on amelogenin function in enamel evolution.  Tooth enamel consists of tightly packed
Enamel Structure Sophistication through Amelogenin Evolution
The overall long-term objectives of this research are to elucidate mechanisms by which cell surface metalloproteinases and their secreted counterparts are regulated and interact, activate and degrade peptides and proteins at the cell surface an
MEPRINS-METALLOPROTEINASES OF THE KIDNEY AND INTESTINE
Psychophysiology of Irritable Bowel Syndrome ARRA  The scientific aims are identical to those of the parent grant, namely to (1) identify single nucleotide polymorphisms (SNPs) associated with irritable bowel syndrome (IBS) diagnosis or subtype
Psychophysiology of Irritable Bowel Syndrome ARRA
The proposed experiments are designed to thoroughly test important aspects of the hypotheses presented in the parent grant. Thus the resulting data should greatly advance understanding of how mRNA stabilization is achieved and how this process
Control of Renal Glutaminase Expression during Acidosis
In examining the effect of vitamin C or ascorbic acid on endothelial function as part of DK050435, we made the surprising discovery that ascorbate traverses the endothelial barrier not through the cells, as expected, but around the cells in a p
and as such contribute to rapid MB reformation. Our proposal represents a direct approach to fully understand the pathogenesis and significance of MBs that were first described in 1911 by Dr. Frank Mallory, and may also impact on other inclusi
PATHOGENESIS OF KERATIN-CONTAINING INCLUSIONS IN LIVER DISEASE
In disease states, unfolded proteins accumulate in the endoplasmic reticulum because the folding capacity is exceeded, initiating a cellular stress response (the unfolded protein response or UPR). Our long-term interest is to understand the mol
Regulation of Gene Expression During Stress
Monocarboxylate transporter 1 (MCT1) is involved in the luminal absorption of butyrate in human intestinal epithelial cells (hIECs).  Since, butyrate absorption is crucial in determining colonocyte health and epithelial integrity, it is essenti
Human Intestinal Anion Exchangers:  Function and Regulation
The proposed study builds upon findings from the parent grant and expands the scope of its specific aims, research design, and methods. Specifically, the focus of the parent grant is to apply high throughput genomic approaches in human samples
Obesity is a serious health problem throughout the world, and contributes to an increased prevalence of Type II diabetes, cardiovascular disease, and cancer. Despite a need for therapeutic options to treat obesity, little is known about the mec
Perilipins and Cellular Triacyglcerol Metabolism
The overall goal of this grant is to explore the mechanisms of end-stage renal disease (ESRD) associated with hypertension and hyperhomocysteinemia (hHcys). We seek to define the molecular mechanisms that contribute to the early events mediatin
Hypertension and Glomerular Injury in Hyperhomocysteinemia
This supplement is designed to accelerate the progress in Aim 3 of the parent grant by teaching summer students to prepare mitochondria and sub-mitochondria particles and test the effects of reactive species, as outlined above, on respiration a
Metabolic Signal Transduction in Adipocytes
DESCRIPTION (provided by applicant): The long-term goal of this project is to gain a better understanding of the molecular pathogenesis of urinary stone disease or urolithiasis.  A centrally important function in maintaining urinary system home
Role of Tamm-Horsfall Protein in Urinary Track Defense
DESCRIPTION (provided by applicant): The overall aim of this work is to understand how the growth of the adult pancreas is regulated to provide an adequate supply of digestive enzymes. We hypothesize that growth can occur by two mechanisms. The
Dietary Regulation of Pancreatic Digestive Enzymes
Epithelial-mesenchymal interactions are required for normal intestinal morphogenesis and have a critical role in epithelial carcinogenesis. The focus of the parent grant is to elucidate the role of mesenchymally derived subepithelial myofibrobl
EPITHELIAL-MESENCHYMAL INTERACTIONS IN GUT MORPHOGENESIS
Defective intestinal transport is a central component of many intestinal diseases. Such transport, in the form of nutrient, ion, and water absorption, is accomplished by specific transcellular transporters as well as passive paracellular moveme
PHYSIOLOGICAL REGULATION OF INTESTINAL EPITHELIAL TRANSPORT AND BARRIER FUNCTION
Claudins are tight junction proteins that determine paracellular permeability and probably form the lining of the paracellular pore. In the renal tubule, they play important roles in electrolyte and acid-base handling. The long-term goal of thi
Expression, Function and Regulation of Renal Claudins
The overarching goals of this supplemental application are: 1) accelerate the tempo of studies outlined in the parent application to elucidate the molecular mechanisms responsible for polarized targeting of a kidney potassium channel that helps
Polarized Trafficking of K+ Channels in the Kidney
The original aims of DK64668 were to interrogate the basic mechanistic underpinnings of microvascular dysfunction that develop in the OZR model of the metabolis syndrome and to determine how these alterations contribute to a impaired state of s
Skeletal Muscle Microcirculation in Obese Zucker Rats
The nature of the signals that regulate intestinal stem cells and mediate the establishment of this hierarchical organization of the epithelium during normal gastrointestinal development has not yet been defined. We have recently found that exp
Growth Factor Signaling in Intestinal Development
cells are activated into proliferation and migration as well as to determine if the phenomenon of fusion is universal or isolated to certain hepatic injuries. This proposal is directly related to specific aim III of the parent grant.  We have
The awarded supplement relates to specific aims 1 and 2 of the parent grant (DK065872) on the effects of dietary obesity on midbrain dopamine systems. The proposed experiments are following up on progress achieved so far. We are now adding calo
Effects of Dietary Obesity on Midbrain Dopamine Systems
136 Harrison Avenue, Dept of Pharmacology
Vitamin E (Tocopherol) is the major fat-soluble antioxidant in humans, and serves a critical function in protection against a plethora of oxidative-stress-related pathologies. However, surprisingly little is known about the molecular mechanisms
Functions of Tocopherol Transfer Protein
Title:  Administrative supplement for pyrophosphate in vascular calcification of renal failure.    Pyrophosphate (PPi) is a potent endogenous inhibitor of vascular calcification.  The purpose of the project is to apply new techniques , specific
DESCRIPTION (provided by applicant): Ferroportin (Fpn, IREG1, MTP1) is the only identified transmembrane iron exporter in vertebrates. Our preliminary data indicate that hepcidin inhibits cellular iron export by inducing the internalization and
MECHANISM AND REGULATION OF IRON EXPORT BY FERROPORTIN
While bariatric surgery is one of few effective long-term treatments for obesity, it is neither risk-free nor universally effective. The costs associated with surgery and publicity surrounding surgery-related deaths and complications have left
UNDERSTANDING HOW PATIENTS VALUE BARIATRIC SURGERY
The prevailing paradigm regarding the relationship of angiotensin II (AngII) and renal injury is that AngII is uniformly injurious to the kidney.  Our recent studies have found that a chronic infusion of subpressor doses of AngII (SP-AngII) has
Supressor ANGII Determines Acute & Chronic Renal Injury
We have previously identified a point mutation in thes Transient Receptor Potential Cation Channel 6 (TRPC6) gene causing an autosomal dominant form of familial focal and segmental glomerulosclerosis (FSGS). This P112Q substitution causes a mar
CHARACTERIZATION OF TRPC6 AS A CAUSE FOR FOCAL AND SEGMENTAL GLOMERULOSCLEROSIS
The results from this project will provide new mechanistic insights into heme transport in humans and may aid in the development of heme-based nutritional interventions for human iron deficiency.  Identifying how heme-iron is acquired by humans
The Biological Role of Heme in Human Nutrition
DESCRIPTION (provided by applicant): This application is in response to Notice Number NOT-OD-09-058: NIH Announces the Availability of Recovery Act Funds for Competitive Revision Applications, and represents an expansion of our currently funded
REGULATION AND FUNCTION OF DROSOPHILA NUCLEAR RECEPTORS
The requested supplement was to support ongoing research into the effect of glucocorticoids on skeletal muscle structure and function. Many diseases, including diabetes and various cancers, are associated with severe muscle wasting in conjuncti
Subproject for Institution # 07-001092: Glucocorticoid Control of Gene Expression During Skeletal Muscle Atrophy
Obesity has become a major public health problem worldwide such .that in developed countries 10-20% of the adult population is obese. As the rates of obesity rise, so do associated health care costs. Few effective approaches for reducing body w
Effects of Dietary Macronutrients on Regulation of Energy Balance
ADMINISTRATIVE SUPPLEMENT FOR ENHANCING THE EFFECTIVENES OF A CULTURALLY SENSITIVE ORGAN DONATION INTERVENTION This Phase II randomized effectiveness trial utilizes a 2x2 simple factorial design with four conditions: (a) Enhanced DVD shown in a
ADMINISTRATIVE SUPPLEMENT FOR ENHANCING THE EFFECTIVENES
The control of gene expression is at the core of biological development and homeostasis. In recent years, an unexpected form of gene regulation has been discovered in which small RNA molecules known as microRNAs (miRNAs) repress the expression
MICRORNA IN LIVER DEVELOPMENT AND DISEASE
A number of diseases affecting the gastrointestinal tract are characterized by the dysregulation of ion and fluid transport resulting in diarrhea or constipation. Over the past fifty years, a plethora of studies have focused on possible mechani
CD48 is a member of the SLAM/CD2 family of leukocyte cell surface regulatory molecules whose gene is located within the lupus-associated Sle1b region of mouse chromosome 1. C57BL/6 (B6) mice with genetic ablation of CD48 (B6.CD48-/-) develop au
Immune and Genetic determinants of murine glomerulonephritis
DMT1 is a widely-expressed iron transporter that is essential for adequate intestinal absorption of iron and for transport of iron in red blood cell precursors for the production of hemoglobin. Rare mutations in DMT1 cause severe microcytic ane
Divalent Metal-Ion Transporter DMT1 and its Role in Intestinal Metal-Ion Uptake
Disturbances of iron metabolism increase morbidity and mortality and are among the most common disorders affecting humans. Nearly 20% of women of reproductive age in the US are iron deficient, and iron overload is increasingly being recognized
Primary Hyperoxaluria type I (PH1) is a severe kidney stone disease caused by deficiency of the protein alanine: glyoxylate aminotransferase (AGT). In many patients, deficiency of AGT results from missense mutations that decrease the stability
Supplement: Analysis of PH1-associated alanine: glyoxylate aminotranferase (AGT) using yeast
number of high school student(s)  college student(s)  science educator(s)  etc.) in health-related scientific research.
Solid State NMR Studies of Peptides and Proteins
Upgrade interoperable radio equipment for the Thibodaux Police Department
Thibodaux Police Recovery Act ARRA Project
The City of Opa-locka, through the police department, will utilize its Fiscal Year 2009 Recovery Act JAG award to increase the department's capability to carry out its public safety mandate by upgrading critical communications equipment and exp
Opa-locka Police Equipment Enhancement Project
To acquire equipment and technology that will improvelaw enforcement capabilities, combat crime, and promote community policing.
This grant program is authorized by the American Recovery and Reinvestiment Act of 2009 (Public Law 111-5)(the 'Recovery Act') and by 42 U.S.C. 3751(a).  The stated purpose of the Recovery Act are: to preserve and create jobs and promote econom
The purpose of this grant is to improve the efficiency and effectiveness of law enforcement and criminal justice programs in the city of Columbus, Georgia by providing equipment, operating supplies, improved training capabilities, and outside c
Our project is entitles 'Eyes on Target'. The Greenville City Police Department continues to stive towards the enhancement of public safety through the use of modern technology. One of these avenues, involving the scope of this project, since t
FY 2009 Recovery Act: Funds used to increase efficiency of School Resource Officers through Wireless Communication Cards added to notebook computers. The goal was to add the cards and train the SRO's on the use. That goal has been obtained and
Waterford Police Department Enhancement of Services Project: for equipment and capabilities upgrade in 6 areas - License Plate Reader, Tasers, Rifles, Treadmill, Ballistic carriers and plates, and Promethean smart board.
Waterford Police Department Enhancement of Services Project
The City of Huntsville, AL will serve as the fiscal agent for all funds awarded and the funds will be allocated to the Huntsville Police Department, Madison County Commission, and City of Madison. The Huntsville Police Department will use funds
Justice Assistance Grants - Formula - For Law Enforcement equipment purchases
FY 2009 Recovery Act Justice Assistance Program
The Onslow County Sheriff's Office have added two K-9 animals to their program to replace animals that are aging out and can no longer perform their duties . These animals will be purchased and trained along with two handlers.  The Sheriff's of
Purchase and implementation of K-9 animals, iRecord system and Veripic software into operations, digital microscope and automated finger print system
BJA FY 09 Recevery Act Edward Byrne Memorial Justice Assistance Grant Program Solicitation
The ARRA Justice Assistance Grant (JAG) provided funds to support a broad range of activities to prevent and control crime and to improve the criminal justice system.  The activities include, but are not limited to, the purchase of equipment, s
The goal of this project is to improve technology and enhance the Department's efficiency and effectiveness in detecting and deterring crime by purchasing items such as security cameras, laptop computers, prisoner transport seat and automated f
Please list the description as   - The county of Montcalm will use its Fiscal Year 2009 Recovery Act JAG award to purchase in-car video cameras for the Montcalm County Sheriff's Office's Patrol vehicle fleet.
The City of Tupelo will use JAG funding to purchase law enforcement equipment in order to enhance the safety, efficiency, and productivity of the Tupelo Police Department's 115-officer force and special operations units, and to provide medical
There are three identified areas that we anticipate using the grant funding in order to improve the areas listed below; 1.	To improve our ability to enforce State and Local traffic laws by enhancing our current processes for enforcement with te
All grant activities will improve law enforcement officer effectiveness and safety in the 943 square mile rural area that is home to more than 12,599 citizens.  The grant's purpose and expected outcomes are to strengthen local law enforcement
City of Falfurrias/Brooks County JAG Formula Local Grant Application
BJA FY09 Recovery Act Edward Byrne Memorial Justice Assistance Grant Local Solicitation
Winchester/Clark County Community Recovery Project 2009
To enhance communnications and public safety throuought the county by replacing failing radio repeater equipment utilized by all Public Safety entities.
Regional 800 MHz Radio Improvement Project
Money used for community policing projects and o purchase equipment for patrol vehicles
Mineral Wells Police Department/Palo Pinto County Sheriff's Department Recovery 2009
continued funding for Director Support Services,New Milford Police Department
This grant funds equipment for five (5) officers awarded under the COPS Grant, to include vehicles (with all related equipment), radios, uniforms, firearms and computers.  In addition, other equipment was funded through this grant, to include P
This is a BJA - Byrne Grant from FY09 Recovery Act to purchase two police vehicles in order to better protect the community.  All funds have been expended.  Vehicles were ordered on 08/13/2009 via State contract and received on November 30th.
PRISONER BOOKING, EVIDENCE COLLECTION AND MDC ENHANCEMENT
The County of Lincoln will use the Fiscal Year 2009 Recovery Act JAG award to support a program that prosecutes illicit drug dealing and manufacturing in the community.
Saginaw County, serving as the fiscal agent for this award, will share the Recovery Act JAG funds with five disparate jurisdictions within the county. In a disparate situation, the units of local government must apply for an award with a single
Saginaw County 2009 Recovery JAG Project
These funds will provide police vehicles, technology equipment to enhance the communication between officers and agencies, updated computers, software and tools for gathering and documenting evidence.  These items will be provided to the police
Kanawha County Multi-Jurisdictional JAG Program
Upgrade the existing radio communiciation equipment.  Specifically, funds will be used to purchase six radio receivers.  The replacement of these receivers will bring the City into narrowband compliance as required by the Federal Communication
The city of Indianapolis, under the Fiscal Year 2009 Recovery Act Jag grant, has selected for funding criminal justice programs that will preserve and create jobs, promote economic recovery, and prevent and control crime based on local needs an
BJA FY 09 Recovery Act Edward Byrne Memorial Justice Assistance Grant Local Solicitation
The Allegan County Recovery Act JAG funds are to support a Problem Solving Court. The program involves collaboration between multiple County agencies and the City of Allegan.  The target groups are non-violent mental health and or substance off
The City of New Haven through the New Haven Police Department (NHPD) will utilize their Fiscal Year 2009 Recovery Act JAG award for an Effective Law Enforcement and Community Policing Program. The main goal of this program is to improve NHPD ef
The Charlotte County Board of County Commissioners (CCBCC) grant proposal is designed to significantly enhance the effectiveness of our Criminal Justice System as well as to preserve jobs. This will be accomplished through the purpose areas of
Charlotte County Recovery and Technology Initiative
The JAG grant funds will be used for equipment and supplies to improve and enhance forensics, officer safety and technology on the department. The equipment and supplies will allow for more efficient and effective operations decreasing time spe
Technology, Forensic and Safety Equipment Project for the Manitowoc Police Department and the Manitowoc County Sheriff Squad Video Project.
JAG-MDT Communications System Project for Gadsden County
MDT Communications System Project for Gadsden County
Nassau County, through the sheriff's office, will utilize the Recovery Act JAG funds to improve and enhance law enforcement in the county. The Nassau County Sheriff's Office will hire four new full-time deputies to serve in two targeted areas o
2009 Nassau County Sheriff's Office Staffing Project
The Anoka County Law Enforcement Initiative. The program intends to assist in economic recovery efforts through the purchase of law enforcement and technology based equipment from American vendors and local companies.  The equipment includes bu
The Anoka County Law Enforcement Initiative
Retain three police officers for the period of April 1 thru June 30, 2010
Awarded funds to purchase camera for our Crime Camera Project.  project complete
St John the Baptist Parish Recovery Act Jag Program
Purchase In-Synch Reporting System and other miscellaneous equipment items for Wood County Sheriff Department
Equipment for Wood County Sheriff Department
This JAG Recovery Grant will be used to purchase technology equipment to enhance the police department's current patrol, investigative, and administrative support functions.
Purchase of patrol rifles and accessories, undercover camera system, and patrol office furniture.
Washington County, serving as the fiscal agent, will purchase an emergency response vehicle for the Washington County Sheriff?s Office. The Sheriff?s Office needs a car for their Crisis Negotiation Unit, who has responded to situations in which
The Auburn Police Department, in conjunction and cooperation with the Cayuga County Sheriff?s Office are applying for funding through the American Recovery and Reinvestment Act (Recovery Bill) made available through the Edward Byrne Justice Ass
BJA BY09 Recovery Act Edward Byrne Memorial Justice Asstance Grant Program
FY 2009 Justice Assistance Grant Program (FY 2009 Recovery Act (BJA-Byrne JAG)) for equipment/technology purchases. Improving Officer Response through Technology.
Funds provided computer work stations and in car video systems for patrol vehicles.
FY 2009 Recovery Act Justice Assistance Grant Program - The City of Rio Rancho, NM, is the Fiscal Agent for this grant, has received and distributed grant funds, and manage reporting for the grant.  The County of Sandoval, NM used the $31,395 i
BJA FY 09 Recovery Act Edward Byrne Memorial Justice Assistance Grant Program - Local Solicitation
Palmetto Technology Improvement Project for Police Department
Purchase of mobile data terminals for increased efficiency
The funds asisted in purchasing two police cruisers.
Leavenworth Technology, Equipment, and Investigative Personnel Project
Purchase of a records tracking system,video equiptment for police cars and finicial training.
This grant was used to purchase equipment such as firearms and computers. We also purchased a new patrol vehicle and tasers. These items were necessary for officer safety
FY2009 Recover Act Justice Assistance Grant Program
The City of Slidell, through the police department, will utilize its Fiscal Year 2009 Recovery JAG award for police technology and communications improvements.  The City of Slidell Police Department will implement a wireless mesh network in ord
Police Technology and Communications Improvements/ FY09 Recovery Act JAG Program
Slidell Police Department 2112 Sgt. Alfred Drive
FY2009 Recovery Act Justice Assistance Grant Program - Law Enforcement Digital Video Equipment Purchase
Law Enforcement Digital Video Equipment Program
The primary goal of this grant project is to enhance law enforcement in Albemarle County, Virginia.  The primary law enforcement agency is the Albemarle County Police Department (ACPD).  The original scope of the project was to use 95% of the f
Digital Mobile Radios & Fingerprinting - With the 1st phase, Digital Mobile Radios, we will purchase and install 18 digital mobile radios, thereby outfitting our entire fleet.  The digital radios will provide clear and consistent communication
To invest in law enforcement equipment and training to improve employee safety and operational effeciencies, and reduce vehicle maintenance costs so that the public is better served by the City Police Department.
St. Clair County has created a Commercial Motor Carrier Enforcement Program.  This prgram is intended to preserve our local infrastructure (such as roads) by enforcing weight restrictions on local roads and inspecting the vehicles as well.  The
The city of Leesburg, Florida, through the police department, will continue to use its Recovery Act JAG award to pay for overtime for police officers.  Funding is extraordinarily important because it is used to focus on crime prevention as well
The disparate jurisdictions consisting of Yolo County and cities of Davis, West Sacramento and Woodland California will share the Recovery Act JAG funds in the amount of $363,086 to support personnel within law enforcement agencies.  These agen
Goals of this project include the utilization of allocated funds to purchase, install, and maintain computers and servers in several municipalities. The purchase of new equipment and utilization of modern technology will improve the professiona
Lehigh County Cooperative JAG Disparate Grant
technology improvement and law enforcement programs
fy 2009 recovery act edward byrne memorial jag
BJA FY 09 Recovery Act Edward Byrne Memorial Justice Assistance Grant Program.
Sheriff's Office Economic Recovery Initiative
York County Byrne Grant.  This project supports local law enforcement agencies within York County with the use of equipment, technology and vehicles as spelled out in the ARRA Bryne grant announcement.
Sitka Police Department Blade Center Server System Upgrade to reduce the number of servers needed to operate the E-911 system, radio communication and the back up power suppliers for each system.
The project consisted of purchasing 1 police cruiser for the City of Charleston Police Department.
THIS GRANT IS BEING USED FOR PERSONNEL COSTS FOR THE INVESTIGATION AND PROSECUTION EFFORTS OF THE TRI-COUNTY DRUG ENFORCEMENT TASK FORCE.
The disparate jurisdictions consisting of Sonoma County and the City of Santa Rosa will use its Recovery Act JAG award in the amount of $704,302 to support projects for the Sonoma County Sheriff, District Attoreny, Public Defender, Health Servi
The disparate jurisdictions of Ulster County and the City of Kingston will use their Fiscal Year 2009 Recovery Act JAG award in the amount of $76,577 to purchase vehicles and support overtime.  Ulster County will use $26,074 to support task for
Investigative Overtime and Police Vehicle Project
Physical Training Continuation and Law Enforcement Equipment Purchase Grant.  The main purpose of this grant is to purchase physical exercise equipment to continue a department physical training program.
Physical training continuation. Law Enforcement equipment purchases
Grant award will fund the Suwannee County Drug Task Force, which is a multi agency unit that investigates narcotic related crimes within Suwannee County, Florida
The goal of this award is to enhance our department equipment needs, training and technology upgrades resulting in improved officer safety, job performance improvement and keeping up with technology advancements.  They outcome will be improveme
gang prevention and public safety equipment.
Purchase of 6 marked cruisers, 1 marked conveyance vehicle, 1 marked crime scene vehicle, uniforms and equipment, and 312 TASERS. Measureable outcomes will be milestones identified in the bid process, purchasing, equipping, and delivering each
Support of Officers Using Recovery Act Funding
Creating Jobs and Employment to Improve the Criminal Justice System is a project wherein 4 added employees work to capture CJ paper records to digital format, and one employee works with families of juvenile offenders.
This US Department of Justice, Office of Justice Programs', Bureau of Justice Assistance Grant will assist local government to improve the functioning of the criminal justice system through the acquision of specific equipment to aid in law enfo
To Enhance Patrol Division with Added Technology
Awarded funds will be utilized to perform upgrades to the police departments computer system and local area network (LAN)
The Fremont County Sheriff's Office and the City of Riverton, WY received the above mentioned grant on August 6, 2009. Due to the changes in Administration and the length of time since receiving the grant award, the needs of both agencies have
Project goal is to install a updated surveillance system at the Palm Springs Police Department, City Hall, Skate Park, Visitor's Center, and various locations located in downtown Palm Springs.  The project outcome is to enhance public safety by
Henderson County Texas is implementing the Patrol and Investigation Enhancement Program.  The program is disigned to reduce crime by mere visibility of law enforecement through out Henderson County Texas.  When crime does occur, the program is
Patrol and Investigation Enhancement Program
Enhanced DUI Enforcement II; purchase three in-car video systems, hardware & software
Enhancement of the operational effectiveness of patrol officers using mobil computers and software and to provide economic stimulus through purchasing supplies and service from American vendors and manufacturers.
Mobile Computer Terminal and Software Enhancement
To purchase AR-15 Rifles for our patrol officers
implementation of community based anti-gang intervention program
Santa Rosa County will use the 2009 Recovery Act JAG funds to establish an intelligence deputy position within the Santa Rosa Sheriff?s Office Narcotics Unit. Duties and responsibilities will include coordinating the overall use of criminal int
This award will address lack of common radio frequencies that impact the ability of multiple agencies to quickly and effectively communicate with each other during a disaster.
Emergency Operations Center Technology Improvements Project
to purchase software, equipment and supplies to the activities of the Rogers Police Department
It is the goal of this project to create an electronic storage system that allows us to store our digital photographs/audio/vieo recordings we seize as evidence.  This system will work with the ICOP digital recording systems we use in our patro
Edward Byrne Memorial Justice Assistance Grant Program to local law enforcement.
Crime Prevention Programs for teh City of Sparta and the City of Tomah
These funds are used to coordinate gang prevention and education strategies in our community through the Staunton, Augusta County, and Waynesboro (SAW) Coalition.  Goals of the SAW Coalition are 1) to expand the membership of the SAW Coalition,
The 2009 JAG Equipment and Technology Program is a grant awarded to the City of Iowa City representing the law enforcement agencies in Johnson County, Iowa including the Iowa City Police Department, the Johnson County Sheriff's Department, Cora
The purpose of the Recovery Act JAG awarded to the City of Salinas, California, and through the City, to eight other jurisdictions, is to support a variety of law enforcement activities to address crime and gang problems in Monterey County.  Th
The El Dorado County Probation Department proposes to utilize the 2009 Edward Byrne Memorial Justice Assistance Grant to provide Probation staffing for DUI and Behavioral Health Courts in El Dorado County. Both of these Courts have been operati
Probation DUI & Behavioral Health Courts
JUDICIARY COURTS OF THE STATE OF ARKANSAS
TO FUND THE DESHA COUNTY ADAM PROGRAM, A SUBSTANCE ABUSE EDUCATION AND PREVENTION PROGRAM FOR JUVENILES
Louisville/Jefferson County Metro Government will use the Recovery Act JAG funds of $5,030,037 to purchase approximately 146 patrol vehicles for Louisville Metro Police, create an electronic subpoena/court notification system and create a day r
The City of Chickasha has seen an increase of 20% in crime statistics during the first quarter of 2009 as compared to the first quarter of 2008.  Violent crimes has reduced but property crime has increased.  The Chickasha Police Department and
Crime reduction and criminal prosecution program
Grant to retain existing patrol officers that would otherwise loose funding.
Law Enforcement Programs - Deputy Retention
Yankton integration, updating, & enhancement project
Yankton integration and enhancement project
The disparate jurisdictions of Jackson County, and the cities of Kansas City, Blue Springs, Grandview, Independence, Raytown, Lee's Summit, and Sugar Creek will use Recovery Act JAG funding in the amount of $4,345,677 to hire staff, improve off
GOALS OF PROJECT: 1) Technology Improvement 2) Extract old law enforcement data  3) Convert and create electronic access to data  DESCRIPTION OF STATEGIES USED: 1) Evaluation & planning for most effective and cost efficient means to meet projec
Award funds were used to purchase and install digital video systems in some of our patrol units.
Purchase fingerprint technology and in car video cameras that will enhance their crime fighting and community policing capabilities.
The Morganton Department of Public Safety is the police and fire services provider for the citizens of the city of Morganton, NC; we employ 65 sworn Law Enforcement Officers (LEO) through five patrol divisions, criminal investigations and admin
Morganton Dept. of Public Safety Upgrade of In-Car Camera System
FY 09 RECOVERY ACT EDWARD BYRNE MEMORIAL JUSTICE ASSISTANCE GRANT PROGRAM
The award funds will be used to purchase twenty-one (21) electronic control devices and related equipment and materials.
Electronic Control Device Acquisition and Deployment Project
A project aimed at reducing crime by targeting criminal activity and tracking suspected terrorists through the use of audio/video surveillance equipment and tracking devices.  The equipment will be used by the Criminal Investigations Division o
With the continued violence in Mexico, particularly Ciudad Juarez, the potential for a joint response by all law enforcement agencies in the El Paso region exists.  The El Paso region is located on the border between the United States and Mexic
The City of Flagstaff and Coconino County will apply Recovery Act JAG funding towards separate initiatives aimed at enhancing law enforcement services provided to the community including Block Watch, a community crime prevention program. The ci
CITY OF FLAGSTAFF, FLAGSTAFF POLICE DEPARTMENT DISCRETIONARY OVERTIME GRANT
Technology Enhancement Goals/Outcomes: I would like to extend my sincere appreciation and gratitude for the 2009 BJA Recovery Act funds that were awarded to Pittsfield Police Department. As our department continues to search for new ideas and w
All Other Transportation Equipment Manufacturing
This project will affect all geographical portions of Lee County, FL, by establishing a multi-agency team to make an immediate impact on rising property crime and jail population related to the economic downturn. This project will aid the whole
Lee County Justice Improvement/High Impact on Jail Reduction and Judicial Caseload Caused by Economic Downturn
Grant Adjustment Notice  #3:The grant was awarded to fund non-sworn investigative/operational positions that would have otherwise been lost due the City of Tampa’s economic hardship.  The funding is for 29 positions including benefits for the
Funds are being used to pay for a new mobile database system for the Putnam County Sheriff's Office
FY2009 Recovery Act JAG Program is the Minot Police Department and the Ward County Sheriff's Department joint project for the acquisition of upgraded equipment and technology necessary to enhance efficiency and officer safety while performing e
Police 800 Mhz Trunked Radio Replacements
TO PRESERVE AND CREATE JOBS AND PROMOTE ECONOMIC RECOVERY; TO ASSIST THOSE MOST IMPACTED BY THE RECESSION
THE CITY OF CROWLEY WILL USE 26723 TO PURCHASE LAPTOP COMPUTERS FOR THE CITY POLICE DEPARTMENT. ACADIA COUNTY WILL USE 26950 TO PURCHASE A COMPUTER VOICE STRESS ANALYZER, PORTABLE RADIOS, AND DIGITAL CAMERAS FOR COUNTY LAW ENFORCEMENT.
Crime prevention and law enforcement equipment purchases.
The City of Grand Rapids with five disparate jurisdictions within the county will use the funds for activities and project that will provide meaningful and measurable outcomes consistent with the goals of the Recovery Act. Specifically, funds w
Kent County Law Enforcement Recovery Project
To pilot an enhanced youth mentoring program called Soar to Success which will target at risk students with significant behavioral and academic difficulties by having match's meet at least 90 minutes per week with the mentee.
The DREAMS Center for Arts Education, a youth development program dedicated to building assets through the arts via free-of-charge programming for high-risk, economically disadvantaged youth ages 8-18, will foster mentoring initiatives through:
OJJDP FY09 Recovery Act Local Youth Mentoring Initiative/Mentoring Through the Arts
OJJDP FY 09 Recovery Act Local Youth Mentoring Initiative - Big Brothers Big Sisters of Puget Sound is addressing the problems of juvenile delinquency and gang participation, poor academic performance, and high drop-out rates in King and Pierce
Big Brothers Big Sisters of Puget Sound - King and Pierce Counties Mentoring Programs
Under category 6, the First Judicial District Attorney's Office will use the grant award to provide comprehensive, rapid response in the prosecution of family violence cases. The enhanced intervention will provide essential new responses for th
Juvenile Probation Community Accountability Project
SR 363 NORTH OF PINE STREET CROSSWALKS & SIDEWALKS
SCENIC HIGHWAY US 98 RECONSTRUCTION AND LANDSCAPING
BROOKMEADE DRIVE SIDEWALKS CITY OF CRESTVIEW
LIVE OAK AVE FROM 20TH ST TO 25TH ST SIDEWALKS
8TH STREET FROM RIDGEWOOD AVE/US 1 TO DAYTONA AVENUE
MEMORIAL DRIVE SEBRING PARKWAY MANATEE DRIVE
MAIN STREET (CR 664) FROM DOC COIL ROAD TO HARDEE STREET
HOMESTEAD ROAD SOUTH AT MILWAULKEE BOULEVARD
SR 758 (SIESTA DR) FROM HENSON BAYOU BRIDGE TO SIESTA KEY BRIDGE
CITY OF WEST MIAMI FROM S.W. 64 AVENUE @ S.W. 18 STREET
BROAD STREET FROM UNTREINER AVE TO ALEXIA AVE
PANEL MEMBER FOR GREEN SUSTAINABILITY GRANT
Safety & Resurfacing Potomac River Bridge to I-270
Minot - 4th Ave NW from Broadway to Bypass
Minot - 11th Ave S from Hiawatha to 16th St SW
Minot - 3rd St NE from Hillcrest to 5th Ave NE
BYRON ROAD (CR 19), PROLE ROAD (CR 19B), AND COLLEGE DRIVE
WAYNE COUNTY'S PAVEMENT PREVENTIVE MAINTENANCE VPP PROJECT
LAKE AVENUE BRIDGE OVER CSX RAIL ROAD (NEAR HOLDEN) PM
Provides assistance to schools in the National School Lunch  Program to purchase equipment.
CITYWIDE          , LED TRAFFIC SIGNAL LIGHTS
Asphalt Concrete Overlay, construct bikeway and parkway, habitat restoration, wildlife protection
A/E Design Services for the construction of a bunkhouse at the Rachel Carson NWR.  Addtional funding for permitting service, fees, and Geothermal Test Well.
Architectural and Engineering (A/E) Services (Phase I and Phase II)-- Additonal funding for Geotechnical Investigation and permitting
Rehabilitation of the Rightmeyer House for the United States Department of the Interior, Fish and Wildlife Service, Back Bay National Wildlife Refuge, Virginia Beach, Virginia. Work shall include converting a residential house to offices and vi
The award funds services to the Gulf of Maine Coastal Program from the Student Conservation Association's Conservation Intern (CI) program, which recruits and places qualified young people for environmental and conservation service projects. Tw
Costal Conservation Intern - Gulf of Maine Coastal Program
Pedestrian Walkway Improvements (sidewalk, ADA, Signing, striping)
Widen Grant Avenue to construct a left turn lane  to improve safety.
City of Hercules San Pablo Ave Pavement Rehabilitation
CMC 5153 - From 4 Miles East of Surrey, N & from 17 Miles South & 1 Mile west of Sawyer, N
Tehachapi - H St and Mill St: Green St to State Route 58; Rehabilitation
Overlay, landscape, irrigation upgrade, misc. concrete work
EDGE GRIND AND OVERLAY WITH ASPHALT RUBBER
Sidewalks, curbs and ADA compliant ramps.
Rehabilitating Pavement & concrete improvements
RECONSTRUCT SIDEWALK, CURB AND GUTTER, CROSS GUTTERS, CURB AND RAMPS, GRIND AND OVERLAY, STRIPPING.
ROAD REHABLITATION, INCLUDING COLD PLANE AND ASHPHALT RUBBER
Highway Infrastructure Investment Grant: Urbanized Areas over 200K Population and Available for Use in Any Area (flexible)
Repair sidwalks to meet ADA requirements
We propose to continue our multiscale mechanical analysis of bioengineered tissues. In the current grant, we have used our two-scale model, in which the microscopic scale represents the collagen fiber network, and the macroscopic scale represen
MULTISCALE MECHANICS OF BIOENGINEERED TISSUE
polymer wafer produced using micro- replication. Each fluidic processor will consist of (1) interconnected chip(s) to feed compounds directly from titer plates to the main processor wafer; (2) micromixer that speeds reagent mixing; (3) high su
High Throughput Modular Microfluidic Systems for Drug Discovery/Development
Louisiana State University, Dept. of Chemistry
This supplement award is to support a person for one year, to work on providing test equipment that will allow complete evaluation of the new x-ray tube that is being designed in the parent grant. In the parent grant proposal, we planned to use
DESCRIPTION (provided by applicant): Improvements in the treatment of brain tumors have produced little impact on outcomes over the past three decades. We propose the development of targeted, multifunctional nanoparticles designed to improve th
Nanoparticle Enabled Intraoperative Imaging and Therapy
The goal of this study is to develop and evaluate advanced annular-array transducer technology for rapid, high-definition imaging in significant medical-research applications. The study will assess high frequency ultrasound (HFU, = 20 MHz) annu
HIGH-FREQUENCY-ULTRASOUND ANNULAR ARRAYS FOR OPHTHALMIC AND SMALL-ANIMAL IMAGING
to targeting groups for molecular imaging. We will synthesize clusters of potent, stable gadolinium-based complexes that can be linked to a targeting group in a single step, and characterize these compounds with respect to relaxivity and stabi
Stable, High Relaxivity MRI Contrast Agents
mouse models); 2) to identify mechanisms that underlie the ability of certain toxicants, such as the herbicide dichlobenil, to cause irreversible neurodegeneration to the OM; and 3) to determine the mechanisms that influence resistance to xeno
Olfactory Toxicity of Enviromental Agents
DESCRIPTION (provided by applicant): Transcription factors play essential roles in the processes of neuronal cell fate determination and expression of the mature neuronal phenotype that are necessary for normal development and function of the b
MECHANISM OF DEVELOPMENTAL TOXICITY OF BISPHENOL-A
This is a administrative supplement application for my R01ES009111 grant. It proposes to further develop methods for SNP SNP interactions and pathways based analysis of SNP data. It will support one postdoc for one year and a PhD student at par
Survival analysis methods in genetic studies
This one year supplement grant application is proposed to expand the scope of the original aims of a currently funded R01 to assess the genotoxic mechanism of targeted cytoplasmic irradiation.   The overall goal of this application is to elucid
We propose to elucidate molecular mechanisms underlying paraquat-induced dopamine neuron death in vitro and in vivo. We also propose to identify neuroprotective growth factors and elucidate downstream protective mechanisms against paraquat neur
Dichloroacetate (DCA) is an environmentally important xenobiotics, widely distributed in our biosphere. It is also employed as an investigational drug for treatment of congenital forms of lactic acidosis (CLA). The cardinal manifestations of ch
DICHLOROACETATE KINETICS, METABOLISM AND TOXICOLOGY
The goal of this proposal is to elucidate the eukaryotic DNA damage response through an integrated experimental/computational approach leading to in-silico models of signaling and regulatory networks. Comparative modeling of the networks induce
A SYSTEMS APPROACH TO MAPPING THE DNA DAMAGE RESPONSE
Since recent studies suggest that environmental toxicants can affect the integrity of the genome through effects on epigenetic mechanisms, the extent to which this occurs with different levels and types of Pb exposure need to be studied. Thus,
Environment and Gene Effects on Brian and Behavior
This ARRA supplement will help us capitalize on our recent molecular insights gained in the parent grant by developing a high-throughput assay to screen for molecules that specifically inhibit Rev1/Rev3/Rev7-dependent translesion synthesis (TLS
Mechanism of Eukaryotic Environmental Mutagenesis
The proposed research activities are within the scope and research protocol of an active NIEHS-supported research project R01 ES015988, entitled ?Glutamate Receptors, Oligodendrocytes, and Lead Neurotoxicity?. There are no major changes to the
Subproject for Institution # 06-003373: Oligodendrocytes, Glutamate Receptors and Lead Neurotoxicity, aka ES-Derived Human Oligodendroglial Lineage Cells for Testing Developmental Lead Neurotoxicity
Silicosis develops many years after initial exposure to silica particles and is characterized by chronic inflammation, lung fibrosis and ultimately respiratory impairment. There is no effective treatment for silicosis. The biochemical mechanism
The Role of ECSODF in Lung Repair after Silica-Induces Injury
The purpose of this supplement is to accelerate enrollment of the EARLI cohort as well as expand enrollment diversity and enhance retention.  Each of the four study sites will hire one additional dedicated outreach/recruitment specialist to hel
Early Autism Risk Longitudinal Investigation (EARLI) Network
The overarching goal of the parent project was to identify lifestyle factors and potential epigenetic mechanisms associated with rapid growth and subsequent obesity in early childhood. Epigenetic factors are mitotically heritable information th
Nutrition, Deregulation of Imprinted Genes
The goal of the current grant is to understand the role of ribbon synapses in communicating visual information in the retina. Visual signals originate in the photoreceptor cells, which then communicate with second-order bipolar neurons via ribb
ARRA:  Cellular Neurobiology of the Retina
This is a request for supplementary funds to support the appointment of an additional Research Scientist and obtain new instrumentation to expand the library of constructs for investigation of protein aggregation disease in vivo.  While it is w
Development and Maintenance of Lens Transparency
This supplement will allow us to greatly enhance the pace of the work on the specific aims supported by the parent grant. Specifically, we will complete the transcriptome and proteome, and develop an initial interactome of neuroprotectin D1 (NP
RPE MESSENGERS, TRANSCRIPTION & PHOTORECEPTOR RENEWAL
This supplement provides project support, both for technical personnel and equipment, to  accelerate the pace of the research.  The goals of this work are to understand the origins of amblyopia, a developmental disorder of vision, and to evalua
regions and collector channels. Preliminary studies using 3-dimensional micro computed-tomography (3D-micro-CT) suggest that this non-invasive imaging technology (resolution to 2 um) can be used to study the 3-dimensional structure and inter-r
Cellular Biology of the Trabecular Meshwork
The goal of this administrative supplement for infrastructure support is to increase the tempo of research and expand the scope of work related to all the Specific Aims of the parent grant, 'Regulation of pHi and Fluid Flux in Corneal Endotheli
Regulation of pHi and Fluid Flux in Corneal Endothelium
This supplement is requested to enhance the accomplishment of the aims of the parent grant and extend our ability to investigate new questions. This will be achieved by:  (1) hiring a new research assistant who will increase our capacity to obt
This competitive revision application seeks additional funding for new aims that are being proposed for original grant application RO1EY10343. The original application sought funds to further our studies of the mechanisms of ischemic preconditi
THE ROLE OF ADENOSINE IN RETINAL ISCHEMIA
Visual opsins maintain a weak, constitutive activity that can be modulated pharmacologically. Retinoids, including the truncated analog, b-ionone, increase the activity of opsins of rods and the opsins of all cones except the red-sensitive one.
ARRA-Multiple Ligand Binding Sites of Rod & Cone Opsins
The goal of this supplement is to utilize next generation sequencing technologies to identify novel, human glaucoma genes and identify valuable mouse mutations for studying glaucoma. Major goals of my parental R01 (EY011721) are to provide new
Award Title – Molecular Analysis of Microdissected Human Lenses.  This supplement will determine the key molecular requirements for Methionine Sulfoxide reductase (MsrA) repair of alpha-crystallin chaperone activity.  It will provide data tha
Molecular Analysis of Microdissected cataractous Human Lenses
The purpose of this application is to explore how high level planning signals can be used for control of neural prosthetics to assist paralyzed patients. This study has both scientific and engineering components. The scientific investigations e
NEURAL PROSTHESIS USING POSTERIOR PARIETAL REACH REGION
This award provided a summer research experience for three students in health-related scientific research.  Throughout development, and in the mature retina, precise control of gene expression is essential for photoreceptor integrity and functi
Coordination of Gene Expression in Retinal Development
During retinal development, the decision to exit the cell cycle must be precisely coordinated with cell fate specification and differentiation to ensure that the correct proportion of each cell type is generated. The Rb family of proteins (Rb,
CELL TYPE-SPECIFIC ROLES OF RB IN RETINAL DIFFERENTIATION
is emphasized as central to our hypothesis that the anterior segment is a dynamic system, and the iris contour is determined largely by dynamic effects. The effects of accommodation, blinking, and pupil diameter are not due to the position of
MECHANICAL INTERACTION BETWEEN AQUEOUS HUMOR AND IRIS
Neurological cytokines have shown tremendous therapeutic potential for preventing or delaying neurodegenerations, including those causing retinitis pigmentosa and dry macular degeneration. The broad-spectrum protective activity of leukemia inhi
CYTOKINE REGULATION OF PHOTORECEPTOR GENE EXPRESSION
This project examines the neural basis of spatial navigation, distinguishing between  visual and nonvisual (amodal) spatial codes. This knowledge is critical for development  of rehabilitation strategies in the blind.  In particular, further ch
PLACE REPRESENTATIONS IN THE HUMAN VISUAL SYSTEM
This proposal describes an innovative nutritional/pharmacological strategy to prevent proliferative retinopathy in a mouse model of disease with the expectation of a later clinicaltrial of patients with diabetic retinopathy(DR). DR has inflamma
Dietary control of angiogenesis in retinopathy model: basis for clinical trials
During rapid eye movements, we are not aware of the motion of the retinal image, nor do we perceive the world to be in a different place after every eye movement. This shows that, somehow, the brain corrects for the movement of the eyes when tr
The transport of proteins inside ciliary axoneme is essential for cilia formation, maintenance, and function.  It is referred to as the intraflagellar transport (IFT).  This mechanism involves a group of proteins that associate together, formin
The proposed work aims to understand early cortical mechanisms of vision in alert and in non-alert subjects. Thanks to the development of behavioral methods for the control of eye position, great advances have been made in understanding central
Cortical Processing of Visual Information During Alert and Non-Alert Brain States
A residue level visualization of protein structures changing with time through associated water in transmembrane (TM) helices, proton channels, fast folding proteins, reverse transcriptase inhibitors and fibrils will be obtained by two dimensio
ULTRAFAST PROCESSES IN PROTEINS AND OTHER ASSEMBLIES
. Since these complexes generally contain protein and nucleic acid components (as well as non-covalently bound nucleotides) it is important to monitor sedimentation patterns at multiple wavelengths so that we can determine how much of each inpu
Structure and Relations of Proteins and Nucleic Acids
The long-term objective of this project has been to understand as fully and as deeply as possible, the principles governing the action of the regulatory protein AraC of the L-arabinose operon in the bacterium Escherichia coli and to expand thes
REGULATORY MECHANISMS OF THE E. COLI ARABINOSE OPERON
We aim to conduct genome-wide global run-on and sequencing (GRO-seq) analysis to characterize promoter architecture and nascent transcription activity at a high resolution in induced pluripotent stem cells (iPS) derived from non-embryonic sourc
COORDINATE GENE REGULATION IN ANIMAL CELLS
We propose that the recruitment of endothelial progenitor cells and activation of anti-inflammatory signaling pathways are the mechanisms by which SDF-1a is beneficial in sepsis. 1. We will determine the effect of CTCE-0214 on the cecal ligatio
We will conduct two studies that will serve to improve and enable the accomplishment of the specific aims of  5R01 GM030758: 28-29.  The first addresses time and data loss due to human cells migrating off the fields of view during the time laps
Centrosome reduplication and consequences of cleavage failure/prolonged mitosis
Accurate segregation of duplicated chromosomes ensures that daughter cells get one and only one copy of each chromosome. Errors in chromosome segregation result in aneuploidy and have severe consequences on human health. Incorrect chromosome nu
ARRA - Structure and Function of a Eukaryotic Centromere
This supplement is a request to accelerate and extend the first two aims of the parent project. The production, purification and labeling of TonS dependent transporters is the most labor intensive aspect of the current project, and ongoing work
Molecular Mechanisms of Membrane Transport
The Flp ('flip') site-specific recombinase is coded for by the 2 micron circle yeast plasmid. Two key pre- chemical steps in combination are: (1) recognition of the target DNA site by Flp and (2) establishing a functional dimer interface betwee
This supplement allows us to access new imaging technology to characterize the dendritic cell intra-cellular altered signaling and receptor co localization which contribute to post injury pathology.  A new post doctorial fellow position, train
IS ABERRANT MO STIMULATION PIVOTAL IN POST-TRAUMA MODS?
and NO, and the decreased translational control of muscle protein synthesis. The sepsis-induced defect is manifested not only under basal conditions but also as a reduced responsiveness to leucine which acts as an anabolic nutrient signal. Our
CYTOKINE REGULATION OF MUSCLE PROTEIN SYNTHESIS DURING INFECTION
Signaling from G protein-coupled chemoanraetant receptors to the various functional responses of human leukocytes involves Rho small GTPases. P21activated kinases (PAKs) are important downstream mediators of Rho GTPase signaling that regulate c
Regulation of Neutrophil Receptor G Protein Interactions
DESCRIPTION: The major goal of this study is to increase our understanding, in terms of structure and dynamics, of the molecular mechanisms that regulate protein function in cellular signal transduction. Signaling pathways comprise numerous pro
NMR Structure of Peptide and Protein Complexes
Cell shape, polarity and motility are controlled by the actin cytoskeleton. How F-actin filaments are assembled into functional arrays is still poorly understood. There are numerous F-actin binding proteins that are capable of cross-linking act
91 N. Eagleville Rd. University of Connecticut
The Klein group proposes supplemental study to accelerate the tempo of scientific research on biological membranes. This research will extend our understanding of the role of proteins (fusion peptides) in facilitating membrane fusion, a key pro
Computer Simulation of Amphipilic Aggregates
mechanism, in which RNAP moves forward on DNA in each nucleotide-addition cycle. Each of these steps is a potential target for transcriptional regulators. Understanding transcription initiation, transcription elongation, and transcriptional re
The purpose of this administrative supplement was to purchase equipment essential to the project and to hire a postdoctoral research scientist to accelerate the tempo of one of the original aims of the research program.  I have purchased a new
Mechanisms of Homologous Recombination in Yeast
In the last 3 months, we developed a method for quantitative analysis of the reactive oxygen species content in mitochondria as a function of position within the yeast cell.  We performed ratiometric imaging of mitochondria-targeted GFP to dihy
The irreversible commitment to M phase requires the explosive activation of the key mitotic driver, CDK1/Cyclin B (also known as M phase promoting factor, or MPF).  Since the molecular identification of MPF in the 1980s, many investigators have
DROSOPHILA GENES AFFECTING CHROMOSOME SEGREGATION
These supplemental funds will be used to obtain additonal personnel and equipment and to replace antiquated pieces of equipment essential to this project. One of the original aims of the parent grant has broadened in scope. Because we have made
The proposed research aims to study regulation of macromolecular transport through plant intercellular connections, the plasmodesmata (PD). PD interconnect most cells within a mature plant and are critical for maintaining and regulating communi
ARRA: Regulation of Macromolecular Transport Through Plasmodesmata
Meiosis is a specialized cell division used by sexually reproducing organisms to produce haploid gametes from diploid cells. This reduction in chromosome number is accomplished by having two rounds of chromosome segregation follow a single roun
ARRA:  Analysis of Meiotic Chromosome Synapsis in Yeast
The supplement covers the cost for replacement of 25-30 year old equipment that is critical to the success of the project. We will purchase a new super-speed centrifuge (about $68K) and a new ultracentrifuge (about $50K).
HISTONE TAIL INTERACTIONS AND FUNCTIONS IN CHROMATIN
This proposal is a Recovery Act Competitive Revision as specified in notice number NOT-OD- 09-058, NIH Announces the Availability of Recovery Act Funds for Competitive Revision Applications. The parent grant is R01 GM054403, IMP Dehydrogenase.
TITLE:  Mechanisms of Tissue Morphogenesis in C. elegans     DESCRIPTION/PURPOSE:  This supplemental project will develop and implement new software for automatic cell identificaiton and tracking in C. elegans embryos.  Work from the parent pro
MECHANISMS OF TISSUE MORPHOGENESIS IN C. ELEGANS
The long term goal of this research is to understand the role of histone modifications such as acetylation and methylation and their effect on chromosome function, using the widely-studied yeast, Saccharomyces cerevisiae, to study these process
ARRA:  Histone Modifying Enzymes and Transcription
The broad, long-term objective of the proposed project is to elucidate the catalytic mechanism of Mot1, a prototypical member of the Snf2/Swi2 ATPase family. Mot1 is an essential, conserved transcription factor that uses ATP hydrolysis to disso
Molecular Analysis of a Yeast Transcriptional Regulator
Determination of a high-resolution structure of the InsP3R C-tail in complex with Bcl-xL will provide a basis for understanding how binding of Bcl-xL affects channel Ca2+ signaling functions, with relevance for cell death mechanisms in cancer a
Electrophysiology of nuclear membrane INSP3 receptor
A significant component of the parent grant is the development and analysis of very complex and biologically realistic spatially and genetically explicit individual-based mathematical models of biological populations. One can say that the compl
New Approaches for the modeling of Speciation
Dept of Ecology&Evolutionary Biology, Dabney Hall 569
The rate of protein-protein association plays critical roles in many fundamental biological processes ranging from enzyme catalysis/inhibition to regulation of immune response by cytokines. Our long-term objectives are to reliably predict assoc
This NOT-OD-09-05 Administrative Supplement Grant supplement request seeks to obtain additional experimental evidence to support a principal finding to emerge from the parent grant, namely, that conditions that enhance errors during protein syn
Mechanisms of mistranslation-mediated mutator response
The long-term goals of our laboratory are to understand though genetic analysis the evolutionary forces producing new species and species differences in behavioral and morphological traits, to identify the genes involved in such differences and
GENETIC BASIS OF SPECIES DIFFERENCES IN DROSOPHILA
The purpose of this grant is to study the function of the annealing helicase HARP in Drosophila melanogaster. In research funded by the parental grant (NIH R01 GM058272), we discovered that human HARP protein has a novel reverse (annealing) hel
Factors Stabilizing RNA Structures (supplement) - The primary purpose of the proposed supplement is the replacement of an aging UV spectrophotometer we use for measuring the free energy of RNA folding transitions. The poor quality of the data a
Maintenance of the epigenetic marks (a set of specific, targeted covalent modifications of DNA and core histone proteins) during various nuclear processes is essential for survival and development of all eukaryotic cells. However molecular mech
Mechanism Transcript Elongation in Chromatin
City of Brentwood Balfour Road Overlay Project
Perform easement boundary survey on the following easements:  Day Creek Easement, Skagit Co., WA; Jensen Easement, Snohomish, Co., WA; Skokomish Farm Easement, Mason Co., WA; Canright Easement, Skagit Co., WA
Asphalt Concrete Overlay & other improvements
W. Yosemite Avenue Asphalt Concrete Overlay in Escalon.
Asphalt Concrete Overlay and other improvements
AC Overlay, Traffic signal mod & other improvements
AC Overlay, Traffic Signal upgrade and other improvements
SELECTIVE RECONST. OF AC PAVEMENT. REMOVAL & REPLACEMENT OF DAMAGED CURB AND GUTTER. NEW HANDICAPEED
RECOVERY:  TAS::12 1142::TAS COTTONWOOD 15 DECOMMISSIONING DESIGN - THIS TASK ORDER IS ISSUED UNDER AN EXISTING IDIQ (COMPETITIVE).  THE ORIGINAL IDIQ DID NOT OBLIGATED FUNDS AND WAS NOT ENTERED INTO FPDS BY THE ORIGINAL CONTRACTING OFFICER.
City of Pleasant Hill Contra Costa Blvd Rehabilitation
City of Clayton, Clayton Road Rehabilitation
Road rehababilitation, cold plane & AC overlay.
impact aid construction formula grants, recovery act
GUIDE RAIL END REPLACEMENT; NIAGARA COUNTY
Highway Infrastructure Investment Grant: Areas of Population equal to or less than 200K
The Department of Medical Informatics & Clinical Epidemiology (DMICE) of Oregon Health & Science University (OHSU) is pleased to submit a competitive continuation for its National Library of Medicine (NLM) fellowship training program for a four
BIOMEDICAL INFORMATICS RESEARCH TRAINING AT OREGON HEALTH & SCIENCE UNIVERSITY
MOF-CRACK SEALING;VARIOUS ROUTES;CAT COUNTY 09/10
VPP-RT 20A; VILLAGE OF ORCHARD PARK WEST
ADVOCATES FOR CHILDREN AND FAMILIES, INCORPORATED
1  Old Town Clinic -  Space Reconfiguring at the Old Town Clinic in order to improve efficiencies and patient access:  Alteration/renovation of clinic work areas,  restrooms, and pharmacy.  Computer equipment installed into exam rooms.  2  12th
ARRA - Capital Improvement Program: 1) Old Town Clinic 2) 12th Ave 3) Detox 4) IT
Capital Improvement Project - Electric Health Record Project and Facility Renovation Project (EHR Implementation at 2 BCHN FQHC Sites (CFCC & FHC) and a Renovation Project at CHCC)    	 Since 1997, Bronx Community Health Network, Inc. (BCHN) an
ARRA - Capital Improvement Program. Clinica received $265,800 to implement a new Practice Management System, and $508,675 to renovate our dental department at our main site at 123 S. Alvarado Street.
CIP/Project 1:  (a) To provide medical equipment for existing space at our Grants Pass medical site to help meet rising demand for sliding fee services and (b) purchase specialized medical and dental equipment.  CIP/Project 2:  To purchase comp
ARRA-Capital Improvement Program Grant These funds were specifically for a small renovation project which allowed for the creation of a call center for our community health center. Patients needing an appointment call and speak to a dedicated s
ILIULIUK FAMILY AND HEALTH SERVICES, INC.
This ARRA-Capital Improvement Program grant award is being used to update much of our lab, other facility and computer equipment and to purchase and install elements of our integrated EHR/EDR/LIS system.  There are three main goals of the proje
The MidMichigan Health Services Capital Improvement program grant is to 1) update and improve medical equipment and instrumentation; and 2) to update and complete minor renovations to the two main primary care clinic sites.
In 2008 Prince William County sponsored a program that enables a local hospital to provide a limited amount of access to prenatal care services for uninsured women below 100% of the FPL. The program served roughly 150 women in 2008. But gaps ex
Project is for immediate capital needs of a Community Health Center including renovations of existing space to increase number of exam rooms, technology improvements (including EMR), and equipment purchases/upgrades. These funds will assit in c
This is a New Access Point (NAP) grant.  The purpose of this grant is to enable the organization to establish and operate a community health center in North Kingstown, Rhode Island.  The goal is to ensure the continuing availability of primary
This IDS grant will allow us to increase medical staff to address the increasing needs of new and uninsured patients.
ARRA - Increase Services to Health Services
The MidMichigan Health Services Increased Demand for Services grant is intended to: 1)increase and expand primary care services, 2) increase mental services, 3) increase outreach services, and 4) increase QI/Staff development
IDS funds have provided resources and support for increased demand for health services at our community health center.  Metro Community Provider Network (MCPN) has used these funds to retain staff. Metro Community Provider Network (MCPN) reques
H8BCS11769-ARRA-Increased Demand for Services Grant
ARRA - Increased Demand for Services (ARRA ? IDS). To expand existing services by increasing health center staff with the addition: of a full time Mid-level providing access to quality primary care with an emphasis on woman?s health; a part tim
GREATER HUDSON VALLEY FAMILY HEALTH CENTER INC, THE
The dire limitations of our current space prohibited expansion of services or improved access to care for patients.  IDS funds have been used to expand services at our satellite site located at 91 Blooming Grove Turnpike, New Windsor, NY. Previ
Retain a case management position that will facilitate outreach and case finding efforts to increase the number of patients seen, the number of encounters provided and the number of follow-up visits completed.  We projected we would see 66 new
UMC received a grant for Health Center Integrated Services Development Increased Demand for Services award to increase services in our new dental program order to meet a large demand for oral health care by low income and uninsured patients. Pr
Arterial Streets Resurfacing - Project #50
RT 15 WATSON CK PRESHO PHASE I EXPRESSWAY CONSTRUCTION
PLATTE RIVER WHOOPING CRANE MAINTENANCE TRUST, INC
This project will partially restore and enhance the ecological functions and values of riverine/grassland habitat along the central Platte River by: 1) restoring approximately 27,000 linear feet of riverine backwater and wetland slough habitat;
Central Platte Valley Wet Meadow and River Channel Restoration Project
Replacement of office air conditioner with energy efficient  R410a SEER 14 unit
I86/ 415 PAINTED POST BRIDGE REPLACEMENT
National Institute of Standards and Technology
The Rice University Brockman Hall for Physics will be a state-of-the-art facility that meets the exacting requirements of modern physics. This building will not only enable new types of experiments, but will also consolidate research activities
Through this award, we will construct a unique Marine Technology and Life Sciences Seawater research building (MTLSS) that will provide an opportunity for transformative multidisciplinary research. At the core of the proposal, the SUrge STructu
MARINE TECHNOLOGY AND LIFE SCIENCES SEAWATER (MTLSS) RESEARCH BUILDING
Elevator and Moving Stairway Manufacturing
S. Toppenish Ave. and Washington Ave. Improvements
The goal is to understand the evolution of microRNAs (miRNAs), the coevolution between miRNAs and their targets, and the role miRNA-target interactions play in the expression divergence between closely related species of Drosophila. miRNAs are
MICRORNA EVOLUTION AND SPECIES DIVERGENCE IN DROSOPHILA
This supplement request outlines our plan to purchase new imaging equipment to accelerate the pace of discovery, and to broaden the approach described in the original grant proposal, which will lead to new discoveries and result in high quality
Signaling mechanisms in cell polarity in yeast
We seek support from the Recovery Act Funds for Administrative Supplements to supplement ongoing NIH grant GM059940, which bears the title,  Mechanism of Mitotic Exit in Budding Yeast . The proposed supplement will allow us to investigate in g
MECHANISM OF MITOTIC EXIT IN BUDDING YEAST
Each cell independently interprets extracellular signals to decide its fate. An outstanding question in developmental biology is how these decisions are coordinated across the developing tissue primordium to produce a functional organ of approp
TGF-beta family regulation of epithelial morphogenesis
The parent grant to this supplement investigates how origins of DNA replication are epigenetically regulated using Drosophila as a model . A DNA consensus for origins has not emerged in multi-cellular eukaryotes. Instead, evidence suggests that
In two previous stages of this project, both funded by the National Institute of General Medical Sciences and carried out successfully, we developed GeneWays, a completely automated system that efficiently distills information about molecular i
COMPUTER SYSTEM FOR FUNCTIONAL ANALYSIS OF GENOMIC DATA
In this proposal, we focus on the mechanisms of assembly and disassembly of mitotic checkpoint complex (MCC).
Regulation of Anaphase-Promoting Complex by Spindle Checkpoint - ARRA Stimulus Admin Suppl
It is now broadly appreciated that the formation of specific tissues and organs within the body arises from the activity of a conserved regulatory network, primarily driven by transcriptional regulatory interactions. In Drosophila, mesodermal c
Genetic regulation of muscle fiber diversity
Acetaminophen (APAP) is the most commonly used medication in the United States but is also the most frequent cause of drug-induced hepatotoxicity. The long-term objective of this research is to elucidate the pharmacogenetic mechanisms that cont
This supplement will allow us to continue our progress in two areas. First, we determined whether our cheY mutants generated by gene shuffling have increased affinity for the target protein FliM in the activated and inactive forms. This informa
Protein complexes Involved in Signal Transduction
With the completion of the human genome project, it has become clear that the number of genes cannot account for the complexity of the human proteome.  This conclusion has lead to a dramatic increase in our appreciation of the abundance and imp
Mechanisms of Enhancer Dependent Splice Site Activation
The ARRA was a supplement to R01GM62437 which relates to basic science research on enzymes that are involved in epigenetics. Specifically, the award covered the purchase of major equipment used to allow more rapid progress toward achieving the
HISTONE MODIFICATION MECHANISMS AND INHIBITION
The goals of our parent grant encompass the development and implementation of new methodology for directed evolution of enzymes, specifically glycosidases (with the potential for use in drug discovery and synthesis) and cellulases (with applict
A Genetic Assay for Protein Evolution and Proteomics
Lipoic acid is an essential sulfur-containing cofacor that is found in several multienzyme complexes that are involved in energy metabolism. In its functional form it is covaleritly attached to the epsilon amino group of a specific lysine resid
MECHANISTIC STUDIES OF LIPOIC ACID SYNTHASE
Retroviral Genomic RNA Dimer Structure and Function  The long terms goals for the parent grant were motivated by the large consequences of retroviruses on human health.  Retroviruses like HIV and HTLV are serious human pathogens and cause extra
Retroviral Genomic RNA Dimer Structure and Function
Endosomes segregate endocytosed macromolecules destined to be degraded in the lysosome from molecules that are either recycled back to the cell surface or routed to other intracellular organelles. The multivesicular body (MVB) is a late endosom
Molecular Analysis of Multivesicular Body Formation
Specifically we will use these additional resources to (1) define the molecular function of a protein domain, which can prevent degradation of ubiquitinated proteins and thus transmit the non-proteolytic ubiquitinsignal. (2) To understand how a
The parent grant, ?Molecular Structure and Function of the Human Kinetochore Outer Plate?, funds efforts to determine the structure of the human kinetochore in order to better understand how it functions. The human kinetochore performs several
MOLECULAR STRUCTURE AND FUNCTION OF THE HUMAN KINETOCHORE OUTER PLARE
We have a bioluminescence monitoring apparatus that assays the circadian bioluminescence rhythms of cyanobacteria and is absolutely essential for Specific Aims D?2 and D?3 and to a lesser extent, Aim D?1 of our grant. This apparatus was constru
We requested funds to obtain an instrument that will allow us to accomplish the same goals described in the parent grant in more than 20-fold less time resulting in a significant acceleration of the pace of our scientific research. This request
STRUCTURAL BIOLOGY OF MITOCHONDRIAL FISSION
E. coli RecA protein promotes the central DNA strand-exchange step of homologous recombination, a fundamental process in all cells for the repair of double-stranded DNA breaks and other types of DNA lesions. RecA (Mr 38 kDa) is an ATPase that p
(ARRA) Structural studies of RecA-DNA complexes
The aims of the parent grant, R01 GM068061, are to elucidate the structures of bacterial single-stranded (ss) DNA-binding proteins (SSBs) cooperatively bound to ssDNA, to reveal how enzymes take advantage of direct binding to SSB to process ssD
Physical Mechanisms of Bacterial Genome Maintenance
Neurospora crassa, which has one of the best understood systems in clock function and light entrainment, offers an excellent experimentally-accessible paradigm for undertanding the clock mechanism.  These studies will help us to describe the mo
Posttranscriptional Regulation of Neurospora Circadian Clock - ARRA Stimulus Admin Suppl
projects will move us most rapidly and efficiently toward the identification, among a surprisingly large set of candidates, of specific polymorphisms and genes responsible for 15 deformed eye (dfe) quantitative trait loci (QTL), illuminating t
Genetic Architecture of Hsp90-buffered variation
The goal of this research project is to test key organizational and functional aspects of centromeres. Centromeres are critical for chromosome segregation, as they are the site of kinetochore formation and mediate chromosome movements during mi
Organization and Regulation of Eukaryotic Centromeres
Innate immune mechanisms are conserved in evolution. The NPR1 protein of Arabidopsis is a master regulator of gene expression in plant defense. Similar to the mammalian immuno- regulator NF-kB, the NPR1 protein is nuclear translocated upon indu
Functional analyses of NPR1 in plant defense
Most modern methods dealing with detecting genetic factors of complex human disorders require the usage of substantial markers. In our parent proposal (awarded 2005) we proposed to study and develop a fundamentally different approach that has s
New Approach Towards Mapping of Complex Human Disorders
Epigenetic changes caused by DNA methylation, histone modifications and histone variants play crucial roles in the regulation of chromatin structure and genome stability, developmental specific gene regulation, genomic imprinting and transcript
DNA Demethylation and Transcriptional Gene Silencing
Phosphorylated inositol phospholipids (phosphoinositides) regulate a multitude of cellular functions via downstream lipid-binding effector proteins. Phosphoinositide-controlled processes include cytoskeletal organization, gene expression, cell
Characterization of Sac1 lipid phosphatases
The purpose of this Administrative supplement is to accomplish new objectives within the scope of the parent award that will 1) increase the scientific value of the project, 2) preserve the job of the current postdoc and 3) strengthen the data
RTE, A PLANT GROWTH GENE WITH A CONSERVED ROLE IN METALS
This Supplement to research grant R01GM072663 (“The Electrochemistry of Diheme Cytochrome c Peroxidases') supports additional spectroscopic studies of bacterial cytochrome c peroxidase (CCP) enzymes, which are studied in the parent grant usin
THE ELECTROCHEMISTRY OF DIHEME CYTOCHROME C PEROXIDASES
DESCRIPTION (provided by applicant): The role of solid-state form in determining the properties of Pharmaceuticals is a critical issue in drug delivery. The ability of a solid to exist as more than one polymorph, supramolecular isomers that dif
POLYMER-BASED APPROACHES FOR EXPLORING POLYMORPH SPACE
Our proposalwill investigate the genetic and molecular basis of complex traits and their interactions with theenvironment using the model plant Arabidopsis thaliana. We will implement a multi use, high density oligo- nucleotide tiling array for
GENOME WIDE ASSOCIATION MAPPING IN ARABIDOPSIS THALIANA
The field of promoter prediction holds almost limitless potential, but has had very limited success. Instead of analyzing DMA sequence homology, we propose a novel method of eucaryotic promoter prediction based on the physical properties of DNA
PROMOTER PREDICTION USING THE OPENING PROFILE OF DNA
NEW KIND OF QUALITY MANAGEMENT FOR X-RAY AND NMR MODELS
GenePattern is a freely available computational genomics environment, with over 11,000 users world-wide, that aims to bring advanced mathematical methods and computational algorithms for the analysis of microarray and other genomic data to the
An Integrative Genomics Data Viewer to Support the TCGA Project
This supplemental effort would take advantage of an exciting collaborative opportunity to cap off the aims and accomplishments of the parent grant, while providing a major service to the biological and biomedical research communities and a job
INVERSE KINEMATICS, STERICS & DATA - TO FIT RNA BACKBONE
The research will provide fundamental understanding of the factors that prevent protein misfolding which is the cause of diseases like cyctic fibrosis and huntington's disease.  The central hypothesis of the proposed research is that non-random
Conformational Properties of Protein Denatured States.
on plant chromosomes. Therefore  each gene must be individually isolated  which is a time-consuming painstaking process. Primarily for this reason  the biosynthesis of the terpene indole alkaloid remains largely unelucidated at the genetic lev
The proposed work focuses on basic structure/activity studies of two molybdenum-containing enzymes, xanthine oxidoreductase and carbon monoxide dehydrogenase. The first enzyme catalyzes the final two steps in purine metabolism in humans, and is
Structure/Activity Studies of Two Molybdenum Enzymes
over the last year thanks to very promising results, which have already resulted in 2 major publications (Bushey et al., Journal of Neuroscience 2009; Gilestro et. al., Science 2009). The parent grant covers 2 full-time salaries (2 post-docs,
Characterization of Sleep Mutants of Drosophila
UNIVERSITY AUXILIARY AND RESEARCH SERVICES CORPORATION
Project Summary/Abstract for more than 30 years, there has been a nationwide effort to encourage students from underrepresented ethnic minorities to pursue careers I nthe sciences.  Despite widespread intervention programs, there remains a sign
specifying common patterns of interactions or pathways, in order to help uncover novel instances. (3) To develop a general structural bioinformatics approach for leveraging properties of specific protein interaction interfaces, and to apply th
PREDICTING AND ANALYZING PROTEIN INTERACTION NETWORKS
that holds cells together, but also direct gene expression in the nucleus. The multifunctional protein, b-catenin, is widely viewed as a model for such adhesion signaling. b-catenin transduces extracellular Wnt signals by interacting with T-ce
Mechanism of b-catenin Targeting to Adhesive or Transcriptional Complexes
The proposed research will investigate the interaction of a protein called dynamin, specifically mutant forms of dynamin, that are implicated in a disease known as Charcot-Marie-Tooth syndrome. The proposed studies will track the movement of th
Dynamin: Ligand Interactions and Conformational Dynamics (Competitive Revision)
The overall goal of this project is to define the role of the cellular ESCRT machinery in the budding and release of intralumenal vesicles in multivesicular endosomes and in the topologically related process of viral budding.  The specific aims
MOLECULAR MECHANISMS OF MULTIVESICULAR BODY BIOGENESIS
We are currently in the last year of the parent grant and have made significant progress toward our stated goals. We have identified a number of novel cis-regulatory modules (CRMs) that support expression along the dorsoventral axis of developi
PATTERNING OF DROSPHILA EMBRYOS BY THE DORSAL-DEPENDENT GENE NETWORK
These studies address the fundamental mechanisms by which SUMO modification regulates gene expression in human cells.  Altered SUMOylation is associated with cancer, neurodegeneration and other diseases in humans.  Increased understanding of SU
MECHANISMS OF TRANSCRIPTIONAL REPRESSION BY SUMO
Central biological functions such as replication, transcription, mRNA splicing, transport, and signaling are performed by molecular machines. Standard structural techniques fail to deal with the large size of molecular complexes and provide min
Embryonic cells polarize to develop specializations needed for morphogenesis and differentiation. Using the C. elegans embryo as a simple model, our long-term goal is to understand how early embryonic cells acquire an inner-outer polarity that
Mechanisms of Contact-Medicated Cell Polarization in the C. elegans Embroyo
Heterotrimeric G proteins play a fundamental role in cell signaling by shuttling the ligand binding information received by G protein-coupled receptors (GPCRs) on the cell surface to effector enzymes and ion channels on the intracellular face o
Co-chaperone role of phosducin-like protein in G protein subunit assembly
A central issue in healthy and diseased cells is how cells sense signals from the outside, and how these signals are used to organize cellular responses. The small GTPase families Ras and Rho are intimately involved in these processes, and muta
CAAX PROCESSING AND CELL SIGNALING IN DICTYOSTELIUM
This award combines two supplemental requests:    1)Double-strand breaks (DSBs) are a major result of endogenous DNA replication errors and of exposure to exogenous DNA damaging agents, and failure to repair such breaks leads to the gross chrom
ENZYME INTERACTIONS AT THE DNA REPLICATION FORK
This is a administrative supplement. It is for expansion of studies relating to the engagement of the heterotrimeric G protein G13 by Sonic hedgehog and other agonists as they relate to the activation of Gli transcription factors.
Engagement of heterotrimeric G proteins by Sonic hedgehog
Heterotrimeric G proteins (123) mediate the majority of signaling pathways in mammalian cells. It is long held that G protein function is localized to the plasma membrane. Observation of the spatio-temporal dynamics of G protein localization in
The goal of this supplement is to initiate a new research direction for the PI in iPS field. The RFWD3 protein is originally identified as a putative ATM substrate in response to DNA damage. Subsequent biochemical analysis in our lab revealed t
FUNCTIONAL ANALYSIS OF A PUTATIVE ATM/ATR SUBSTRATE RFWD3
This supplement request is to accelerate the process of the parent grant entitled “A new role of MEPE/OF45 as a co-factor of CHK1 for DNA damage response,” by hiring new employees. The research design/proposed scientific activities, methods
This application requests supplemental funding for the parent grant 1 R01 GM081510, 'SIS Multicenter Study of Duration of Antibiotics for Intraabdominallnfection.'  The main purpose of these supplemental funds is to hire of an additional resear
SIS multicenter study of duration of antibiotics for intraabdominal infection
This administrative supplement under the American Recovery and Reinvestment Act is to update our spinning disk confocal microcope with a motorized stage and faster camera to facilitate both Aims of the parent grant. These microscope updates wil
Mechanisms of 'End On' Microtubule Attachment by the Kinetochore
This application is to seek a Recovery Act Administrative Supplement to the parent project, 1R01GM081601-1A2 “Functions of tRNA modifications”, which investigates the mechanism of tRNA(m1G37) modification by the bacterial TrmD and the eukar
Our goal is to understand the mechanism of Adeno-associated virus (AAV) receptor recognition and internalization.  AAV is important both as a simple mammalian T=1 icosahedral virus model and also as a successful vector for human gene therapy th
Structural studies of AAV capsids and their glycan receptor interactions
Fires and burns are among the most common causes of death from unintentional injury. In the United States, almost 1.2 million burn injuries are reported annually and despite significant advances in burn care, infection remains a major cause of
Bioformatics Analysis of Control Mechanisms of Hypermetabolism
The capacity for tissue repair is a fundamental property of multicellular organisms that is often critical for survival. Despite its biological and clinical importance, the signals that initiate and terminate epidermal wound closure remain obsc
HUMANIZED MOUSE MODELS FOR THE P53 R72P SNP
Genetic recombination is responsible for the re-assortment of alleles at each generation; for our own species, this means the assortment of disease susceptibility alleles across generations and populations, and for all organisms, generating the
TRANSACTING GENES REGULATING RECOMBINATION HOTSPOT ACTIVITIES
which is known to contain about 20 proteins. An important challenge for the future will be to identify and characterize any proteins that are missing from the current model. The experiments proposed here concern three newly discovered E. coli
Discovery and Characterization of New Bacterial Cell Division Genes
Acetylation of histone H4 N-terminal tail plays a crucial role in gene activation in chromatin environments; and alterations in this epigenetic process can lead to various diseases. Our long-term objective is to understand how H4 acetylation re
Role of Histone H4 N-Terminal Tail in Transcription Regulation
We are establishing C. elegans as a model for studying prostaglandin metabolism, genetic regulation, and biological functions.  Using a combination of genetic analyses, in vivo bioactivity assays, and liquid chromatography-tandem mass spectrome
PROSTAGLANDINS IN C. ELEGANS FERTILIZATION
Proposal to focus on the production of G protein coupled receptors and their structural characterization by a novel NMR based approach. The requested funds will allow us to purchase equipment and hire additional technical help for the productio
A novel approach to integral %26 anchored membrane protein structure %26 function
The proposed work focuses on the development of advanced methods in nuclear magnetic resonance (NMR) spectroscopy for metabolomics-based studies. The rapidly expanding field of metabolomics provides new information on biological perturbations b
Advanced Methods in NMR-Based Metabolomics
The overall scope of the parent EUREKA grant is to characterize the structures of G-quadruplex/i-motif complexes found in promoter regions of a number of important genes involved in proliferation, apoptosis, and development, which will serve as
Establishing a Molecular System for Drug Targeting of Transcriptional Control
In year 2 of the grant, we will have identified the ligand which binds to CG4395, synthesized it and raised antibodies to it. We originally planned to develop competitive ELISA assays to do this, using fluorescence detection. However, we recent
NEUROPEPTIDE MODULATION OF COURTSHIP BEHAVIORS
This project will develop software that is usefule for computational screening in drug discovery projects and takes advantage of otherwise idle computers. The Supplement will support the accelerated development and deployment of a distributed M
DEVELOPMENT AND MAINTENANCE OF THE MEAD SOFTWARE SUITE
that drives sequential Hb-Kr-Pdm-Cas transcription in neuroblasts; and identifying new temporal identity genes. Each of these approaches takes advantage of the powerful genetic and anatomical tools available in Drosophila, but our results shou
Genetic and Molecular Studies of Neurogenesis
The goal of this administrative supplement will be used forjob creation,job retention, and procurement of additional needed equipment that will streamline data collection and analysis enormously.
Linking Early Linguistic and Conceptual Development
developed during the initial funding period, will allow us to test specific hypotheses about the role of cohesion, DMA sequence, and the synaptonemal complex in the establishment of meiotic exchanges. The combined data from these studies will
GENETIC CONTROL OF MEIOTIC CHROMOSOME SEGREGATION
Biotechnology Life Sciences Building 340
The objective is to provide students, educators and researchers accurate, inexpensive and easily accessible visual data on human embryonic development. Aligned digital images of the serial sections of the best normal human embryos in the Carneg
COMPLETION OF HUMAN EMBRYO SECTIONS ON DVDS
The supplement will provide funds for deep sequencing of mutant lines and for bioinformatic analyses of the data. The use of deep sequencing technology will greatly accelerate the pace of discovery for this project.
MUTATIONAL ANALYSIS OF NOTOCHORD DEVELOPMENT
Federal projects STIM-E-6598005 and STIM-E-P511018 combined, involving grading, draining, placing crushed base and bituminous pavement surfacing, electrical and miscellaneous work on 0.32 mile of urban route 051, beginning at reference marker 4
This award is for medical equipment funding for the purchase of a I-CT Scanner.
I-675 ATMS/COMM/SURVEIL FROM I-75/HENRY TO I-285/DEKALB
The award was for (3) pieces of medical equipment Retinal Camera, Electric Exam Table and Podiatry chari. The purpose is to upgrade equipment to improve service delivery and safety related to services which will lead to imporoved patient outcom
Equipment ,Construction, Maintenance, and Sanitation
Grand Forks - Mill Road from Gateway Drive N to Urban limit
Grand Forks - 17th Avenue S from Washington Street to 42nd Ave S
ARRA-Capital Improvement Program For the Health Center at 100 Bullocks Point Ave which included three project. Project #1 Fire detection System,Project #2 HVAC System, and Project #3 Window Replacement at 100 Bullocks Point Ave,Riverside RI.
This award is used to increase the capacity and access to primary medical care provided by our organization. Our plan is to hire or retain a provider and medical support staff, and to extend our hours of operation in our Murray County Georgia l
Grant funds provided to increase service availability for low income uninsured individuals requiring medical care.  Funds are used to offer extended clinic hours for medical and dental services.  Nine additional evening clinic hours were added
ARRA-INCREASE SERVICES TO HEALTH CENTERS
by expanding our current nutrition program and beginning and in-house cardiology program in order to treat our hypertensive and cardiac patients and track our patients compliance.  Affordable services will be made available through diet, exerc
ARRA- Increased Services to Health Centers
AGRICULTURE AND FORESTRY, LOUISIANA DEPARTMENT OF
The Emergency Food Assistamce Program (TEFAP) provides funds to assist with administrative functions of sub-recipient food banks.  100% of administrative funds are passed thru from Louisiana Department of Agriculture & Forestry to the five regi
Assist States in providing schools with funds for the purchase of school cafeteria equipment.
ARRA Equipment Grants for School Food Authorities
Three major renovation projects (floor, walk-in cooler, HVAC unit).
Seminole Nation Food & Nutrition Services Grocery Center Rennovation Project
The purpose of the Salmon Rearing Habitat Restoration & Protection Project at Lynwood Park & Related Habitat Improvements is to implement approximately ¼ mile of streambank restoration in addition to watershed and related riparian habitat impr
Salmon Rearing Habitat Restoration & Protection Project at Lynwood Park & Related Habitat Improvements
Reconstruction Maryland Avenue from Jefferson Street to Short Street
Construction and Mining (except Oil Well) Machinery and Equipment Merchant Wholesalers
Williston - West 2nd Avenue W Frontage Road from 6th Ave W to 42nd Street
STC-8001, MAIN ST; BOISE AVE TO WASHINGTON, EMMETT
Provide a part-time contractor to work under the Asst. Regional Director of External Affairs and assist Regional Office program and information managers with American Recovery and Reinvestment Act communications including 1) internal comunicati
Bridge Deck Replacement Program Roff Avenue over Rt 46,  Construction
This career development plan seeks to build the foundation of the PI's long-term career on integrated research and education regarding sketch-based construction and interaction with geometric content in creative design environments. Studies in
CAREER: Sketch-based Construction and Interaction with Geometric Content in Creative Design Environments
The purpose of the Lead Based Paint Hazard Control Program is to assist local governements to undertake a comprehensive program to identify and remove lead-based paint hazards in privately owned rental and owner occupied housing.
WESTCHESTER COUNTY BRP TRAFFIC DATA COLLECTION
YONKERS TRAFFIC AND PEDESTRIAN SIGNALS LED UPGRADE
Fargo - Old HWY 81 from Dakota Dr to Co. Rd 20
Wahpeton - 7th Street N from 2nd Ave N to 8th Ave N
BRIDGE OVER THE MIDDLE FORK OF THE NORTH BRANCH OF THE CHICAGO RIVER IN NORTHFIELD
SR 155 AT SHOAL CREEK - REPL CLVT; TRN LN AND REMOVE PED BR
This project will investigate the structure of several classes of groups defined by generators and relations, including Golod-Shafarevich groups and Kac-Moody groups. The Principal Investigator will study various asymptotic invariants for these
Kazhdan's property (T), Golod-Shafarevich groups and Kac-Moody groups
FWS SUPPORTS PAYMENTS TO INDIVIDUAL STUDENTS THROUGHT THE ACADEMIC YEAR
TOYOTA TECHNOLOGICAL INSTITUTE AT CHICAGO
RI: Medium: Collaborative Research: Explicit Articulatory Models of  Spoken Language, with Application to Automatic Speech Recognition  ------  Project Description:  One of the main challenges in automatic speech recognition is  variability in
RI: Medium: Collaborative Research: Explicit Articulatory Models of  Spoken Language, with Application to Automatic Speech Recognition
ROUTE 17 OCCANUM TO DAMASCUS, MILL & SINGLE COURSE PAVING
American Recovery and Reinvestment Act:  Funds provided classroom supplies, onsite training, training resources, student salaries, and mileage, to increase the level of education of teachers.  Quality Improvement:  Funds provided the replacemen
ILLINOIS ASSOCIATION OF COMMUNITY ACTION AGENCIES
Funding to provide capacity building and technical assistance to the community action network for their non stimulus activities.
Illinois Association of Community Action Agencies CSBG T&TA: Supported by the American Recovery and Reinvestment Act
COMMUNITY DEVELOPMENT INSTITUTE HEAD START
This award provides ARRA funds for Head Start Quality Improvement and Cost of Living Adjustments (COLA) in accordance with FY 2009 Funding guidance ACF-PI-HS-09-06.  Head Start promotes the school readiness of low-income children through the pr
Head Start-National Interim Management (NIC)
Carretera 874, Kilometor 1.2 Edificio #2
This award provides ARRA funds for Head Start and Early Head Start Quality Improvement and Cost of Living Adjustments (COLA) in accordance with FY 2009 Funding guidance ACF-PI-HS-09-06.  Head Start promotes the school readiness of low-income ch
ARRA for COLA and Quality Improvment for Head Start Program
This is an award for the Head Start Program for Region 12 (Migrant and Seasonal Head Start) ARRA Cost of Living and Quality Improvement increases.  Head Start provides comprehensive educational and health service for children from lo-income fam
This awards Community Action Partnership of San Luis Obispo County (CAPSLO), ARRA funding for Cost of Living Adjustment (COLA) and Quality Improvement (QI) for our Migrant and Seasonal Head Start Program (MSHS). These funds were awarded for two
The overall purpose of the Red Cliff Head Start/Early Head Start ARRA Project was to support Head Start and Early Head Start staff in their work to enhance services to children and families 1) During the fourth quarter, all Head Start staff rec
Red Cliff Head Start/Early Head Start ARRA Project
This award includes: 1) A cost-of-living adjustment (COLA) increase of 1.84% totalling $203,279 for Migrant and Seasonal Head Start staff salaries over the 12-month period following the effective date and 2) quality improvment funds of $317,478
Head Start is and early childhood program that serves children three to five years of age whose parents meet income eligibility guidelines.  The Pueblo of Acoma Haak'u Learning Center Head Start Program serves 112 children and focuses on social
American Recovery and Reinvestment Act Cost-of-Living and Quality Improvement
ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640 (a)(5) of the Head Start Act.   ARRA funds supported a 1.84% COLA for all staff for a total of $12,408.  ARRA funds also were u
LAC DU FLAMBEAU BAND OF LAKE SUPERIOR CHIPPEWA INDIANS (INC)
(1) Full Time Assessment Coordinator/Full Year.  The overall purpose of this award was to hire one full-time Assessment Coordinator for a period of one year to compile and publish a triennial community assessment.  The Award also includes fundi
Head Start-Full Year (this Project Name does not our Early Head Start Program)
The Chickasaw Nation Head Start Program will allocate the ARRA Cost of Living Adjustments (COLA) where each staff member will receive a 3.5% increase in salary. This program will also purchase educational and development classrooms supplies, fu
ARRA Head Start COLA & Quality Improvement
Increase the compensation and benefits of staff though a cost of living adjustment to improve the overall quality of the program and to provide professional development to teaching staff to improve staff qualifications.
Early Head Start/Head Start COLA&Quality/ARRA Funding
This award provides ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start program.  The Head Start program promotes school readiness o
This award provides for ARRA cost of Living Adjustment (COLA) and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start and/or Early Head Start program.  Head Start promotes the
Laguna Headstart ARRA Project/Pueblo of Laguna/Cibola County New Mexico. To address 140 Preschool Headstart Center Based and 70 Early Headstart (38 Home Based and 32 Center Based) children and families and Headstart staff.
Head Start and Early Head Start early childhood education and development program.
The award provides for ARRA Cost of Living Adjustment (COLA) and Quality Improvement funding consistent with the provisions of 640 (a)(5) of the Head Start Act for the Head Start and Early Head Start programs. Head Start promotes the school rea
COMMUNITY DEVELOPERS OF BEAUFORT HYDE INC
ARRA Strengthening Communities Fund Nonprofits Capacity Building Program.  The goal of this program is to build the capacity of our nonprofit partners in order to address the broad economic recovery issues present in our community, including he
Strengthenng Capacity of Eastern North Carolina Nonprofits
ARRA Strengthening Communities Fund Nonprofits Capacity Building Program   The goal of this program is to build the capacity of our nonprofit partners in order to address the broad economic recovery issues present our community, including helpi
ARRA of 2009 Strengthening Communities Fund Nonprofit Capacity Building Program
PENNSYLVANIA FAMILY SERVICES, MONTGOMERY COUNTY OF
The goal of the program is to build our capacity to partner with community-based and faith-based non-profits and to provide training and technical assistance to help nonprofit faith-based and community organizations better serve those in need a
Strengthening Communities Fund State, Local and Tribal Government Capacity Building
BUSINESS, ECONOMIC DEVELOPMENT AND TOURISM, HAWAII DEPARTMENT OF
ARRA Strengthening Communities Fund/State, Local and Tribal Government Capacity Building Program - This award is made to State, city, county, and Indian/Native American Tribal governments (or organizations designated by such governments) in ord
ARRA of 2009 Strengthening Communities Fund State, Local and Tribal Government Capacity Building Program
MONTANA HUMAN RESOURCES DEVELOPMENT COUNCIL DIRECTORS
Title:  CSBG Training and Technical Assistance State Association and Capacity Building (ARRA).  The purpose of the grant is to provide strategic planning, coordination, and technical assistance related to ARRA programs being implemented by Mont
Montana Association CSBG ARRA Planning and Coordination Grant
NORTH DAKOTA COMMUNITY ACTION ASSOCIATION
CSBG T and TA supported by ARRA of 2009. These funds support the Community Action state association to conduct activities to enhance the capacity of the seven ND Community Action agencies.  Activities include organization of meetings, trainings
CSBG Supported by the American Recovery and Reinvestment Act of 2009
WASHINGTON STATE COMMUNITY ACTION PARTNERSHIP
This award will provide critical training and technical assistance to 30 Community Action Agencies in Washington State.  The funding will be used to implement a Community Relations strategy to help better inform the public of  programs created
CSBG Training and Technical Assistance State Association and Capacity Building (ARRA)
FUNDS TO BE USED FOR WATER TRETMENT PLANT IMPROVEMENTS TO CHANGE THE CITY OF MAYVILLE'S WATER SOURCE FROM SURFACE WATER TO GROUND WATER FOR BETTER QUALITY OF WATER FOR MAYVILLE'S RESIDENTS
Loan is to complete the North Central Rural Water Consortium's rural water system in the Phase II area within the CONAC REAP Zone in central North Dakota, providing rural residents with a safe potable water supply.
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  The major objective of this project is to develop the fundamental theoretical framework and algorithms that realize human context awareness in an
CSR: Small: Infrastructure-free Human Context Awareness with a Wearable Sensing and Computing System
Health Diagnostic, Intervention & Treatment Services
The Village proposes to extend the public sewer system to the areas currently not served. The proposed combination gravity/grinder pump-low pressure collection system being considered is a gravity sewer system north of Highway 540, a low-pressu
Village of Logan Wastewater Improvement Project
Contractor payments for this period (payroll and materials); Advertising and Bond requirements for project
Loan for Sewer System Improvements from USDA Rural Development, Water and Wastewater Programs.
Loan for expansion of the Louisa County Regional Wastewater Treatment Plant
Upgrades to Harrison Avenue Area and the South Gardiner Pump Station
In plants, the distinction between species is often not complete, allowing for the production of hybrids that frequently perform poorly. Conversely, within a single species, genetic differentiation may develop between isolated populations resul
Collaborative Research:  Population differentiation in an herbaceous plant: genetic divergence and outbreeding depression
Head Start 2009 ARRA COLA Quality Improvement Funding awarded to improve staff qualifications and credentials, enhance classroom environments and reduce program operating expenses to support the restructuring and relocation efforts.
Head Start Quality Improvement and COLA  (ARRA)
We are hoping to hook up to the existing water and sewer main running along Route 3 here in Tilton, following Daniel Webster Highway.  Our septic tanks are getting older, they haven't been replaced since the park was founded.  We're right by a
White Rock Cooperative Estates Sewer Project
Project-based learning, especially in courses where students work in groups on real-world problems for industry sponsors, is common in engineering curricula. These courses offer students the opportunity to move forward in their trajectory from
Group Cognition: Learning in Engineering Project Teams
This agreement provides funding under the American Recovery and Reinvestment Act of 2009 to the state of Pennsylvania to capitalize its revolving loan fund for the financing for the construction of drinking water facilities, green infrastructur
DRINKING WATER STATE REVOLVING FUND STIMULUS GRANT
All Other Nondepository Credit Intermediation
To study two hybrid organic/inorganicsystems for which the effects of employing IPM Materials will specifically address a primary limitation in each system.  The first is in organic nonvolatile memory devices, where the use of IPMs can lead to
Columbus Municipal School District is awarded a National Clean Diesel Funding Assistance Program Grant to fund a replacement project targeting our school bus fleet.  The general purpose of the grant is to reduce diesel emissions and improve air
ENVIRONMENTAL QUALITY, ARKANSAS DEPARTMENT OF
This project supports water quality management planning activities that are authorized under the Clean Water Act and the American Recovery and Reinvestment Act of 2009.  TMDLs (Total Maximum Daily Loads) for select waterbodies listed on the mos
ARRA - AR - CWA 604(b) - Water Quality Management Planning
The purpose of this application is to build a ten (10) bed replacement hospital and medical clinic in which all ten patient rooms will be private.  The new building(s) includes a 21,410 square foot replacement hospital and 10,208 square foot me
ENVIRONMENTAL PROTECTION, PENNSYLVANIA DEPARTMENT OF
This grant is to be used for Leaking Underground Storage Tank Assessments and Cleanups throughout Pennsylvania.
FFY 2009 ARRA LEAKING UNDERGROUND STORAGE TANK PROGRAM
SOUTHSIDE DRIVE BRIDGE REPLACEMENT, TIOGA COUNTY
COUNTY ROUTE 21, MILL & SINGLE COURSE PAVING
HIGHWAY SIGNAGE UPGRADES, CHENANGO COUNTY
TRAFFIC SIGNAL UPGRADES, SULLIVAN COUNTY
Statewide Guardrail Repair and Replacement
Highway Infrastructure Investment for the Puerto Rico Highway Program.  This poeject consist in the Pavement Rehabilitation and Minor Repairs on the East Region, Unit II.  This highway improvement is a Restoration and Rehabilitation (4R)
Pavement Rehabilitation and Minor Repairs, East Region Unit II
SR6/Raymond to Chehalis River Br - Centerline Rumble Strips
TRANSPORTATION, NEW HAMPSHIRE DEPARTMENT OF
STC-9033, 8TH ST SCHOOL SIDEWALKS, MERIDIAN
North Road Improvement & Pathway Under Railroad Trestle
The purpose of these ARRA-HRSA Public Health Traineeship funds is to increase the number of underrepresented professionals working in the designated shortage areas (Biostatistics, Epidemiology, Maternal and Child Health, Public Health Nutrition
college student drinkers who will be assigned to one of three conditions: a Protective Behavioral Strategies Feedback condition, an education-only control condition, and a Personalized Normative Feedback condition. This latter condition will a
ARRA Protective Behavioral Strategies and Brief Alcohol Interventions
LABOR AND WORKFORCE DEVELOPMENT, ALASKA DEPARTMENT OF
WIA Youth Grants, CFDA 17.259, $3,936,018; WIA Adult Grants, CFDA 17.258, $1,679,456; WIA Dislocated Worker Grants, CFDA 17.260, $3,546,444:The overall purpose of the award is training and reemployment for Adult, Dislocated Worker and Youth.  A
WIA Youth/Adult/Dislocated Workers Formula Combined
WORKFORCE SERVICES, ARKANSAS DEPARTMENT OF
Awards for WIA Youth (CFDA 17.259) $12,065,555, Adult (CFDA 17.258) $5,072,930 and Dislocated Worker (CFDA 17.260) $7,518,483 Formula Grants are designed to provide quality employment and training services to assist eligible individuals in find
WIA - Youth, Adult & Dislocated Worker Activities
To provide work related and training services, including job training opportunities to unemploymed and underemployed as well as expanded summer youth work experiences.
Recovery Act - WIA Adult Activities, Youth Formula Grants, and WIA Dislocated Worker Formula Grants to States.
Recovery Act Workforce Investment Act Formula Programs - WIA Youth $2,918,025 CFDA No. 17.259; WIA Adult $1,234,406 CFDA No. 17.258; WIA Dislocated Workers $2,832,818 CFDA No. 17.260.
COMMERCE AND ECONOMIC OPPORTUNITY, ILLINOIS DEPARTMENT OF
For WIA Youth Grants: To provide employment-related services and high quality work experience, including an expanded summer youth work experience component, to America?s youth ages 14-24 to prepare them for the workplace. For WIA Adult Grants:
Workforce Investment Act - WIA Dislocated Workers Program
EMPLOYMENT AND TRAINING, KENTUCKY DEPARTMENT OF
American Recovery and Reinvestment Act of 2009 (ARRA) funding allocations to supplement PY 2008 WIA Title I Dislocated Worker program. The total award amount of $44,615,045 is separated as follows: WIA Adult $8,192,097, CFDA 17.258; WIA Youth $
ARRA Funded Workforce Investment Act Programs (CFDAs): 17.258 Adult, 17.259 Youth and 17.260 Dislocated Worker
The Workforce Investment Act (WIA) of 1998 created a nationwide federally funded employment and training program and provides resources to states and to local Workforce Development Boards to assist jobseekers and employers with a number of work
ARRA - Workforce Investment Act, Employment and Training programs for Adult, Youth, and Dislocated Workers - under CFDA numbers 17.258($10,337,165), 17.259($25,070,698) and 17.260($44,419,273).
EMPLOYMENT, TRAINING AND REHABILITATION, NEVADA DEPARTMENT OF
WIA Dislocated Worker Grant $14,311,733, CFDA 17.260 To provide a variety of work-related employment and training services, including job training opportunities, to laid-off individuals to support their reentry into the job market.; WIA Youth G
Programs funded under the Workforce Investment Act: WIA employment and training services for adults, dislocated workers, and youth (year round and summer employment).  Adult CFDA =17.258, Youth CFDA = 17.259, and Dislocated Workers CFDA = 17.26
LABOR AND TRAINING, RHODE ISLAND DEPT OF
WIA Adult (CFDA 17.258) - The purpose of this program is to improve the quality of the workforce, reduce welfare dependency, and enhance the productivity and competitiveness of the nation's economy by providing workforce investment activities t
The funds are to be used to assist in the employment and training of dislocated workers, youth, and adults who qualify for services under the workforce investment agency.   The WIA Youth Grants:Provision of employment-related services and work
Install a new 80,000 gallon water storage tank to provide 2.5 days of storage.
The Award was a Summer Supplement to the NIH Parent Grant 2RO1HD042215-06, Left-Right Asymmetry of the Developing Diecephalon under direction of Dr. Marnie Halpern
Left-Right Asymmetry of the Developing Diecephalon
We received notification of our grant award (grant # 3R01HD046589-04S1) on September 22, 2009. Tissue for the two microarray projects have been isolated and shipped to Genome Explorations, Inc. in Memphis, TN on December 9, 2009 for processing.
Prenatal Virally Induced Brain Disorder in Mouse, Supplement
Current nutritional strategies for very preterm infants in this country are resulting in postnatal growth failure from which the neonate does not recover by the time of hospital discharge. Undernutrition, particularly insufficient protein intak
Maximizing Protein Growth in the Early Neonatal Period
Fetal growth restriction (FGR) increases the already substantial risk of prematurity for infants' survival, overall function and later learning competence. Of the 12% of prematurely born infants in the US each year, more than 5% failed to grow
Preterm Fetal Growth Restriction and Development Care
Traumatic brain injury (TBI) is a significant public health problem, with 1.5-2.0 million Americans injured each year.  Cognitive deficits, particularly in the domains of memory and attention are frequently the source of lingering disability af
RCT Methylphenidate & Memory/Attention Training in Traumatic Brain Injury
Muscle atrophy and weakness secondary to disuse are common clinical phenomena, which can significantly impact activities of daily living and present a major challenge in rehabilitation. Rehabilitation programs designed to maximize strength gain
MOLECULAR SIGNATURES OF MUSCLE REHABILITATION
All vertebrates have internal asymmetries along the left-right (LR) axis, such as the asymmetric placement of organs about the midline. Correct asymmetric placement of organs is critical for their function, as it allows for proper connectivity
ANALYSIS OF ZEBRAFISH NPT AND SWT MUTANTS IN LEFT-RIGHT PATTERNING
The childhood obesity epidemic raises important clinical and public health questions about the effects of both obesity and obesity treatment on bone development. Osteoporotic fractures are a major cause of morbidity and mortality in the aged. H
BONE HEALTH OF OBESE ADOLESCENTS DURING WEIGHT LOSS
Endometriosis is a poorly understood gynecologic condition defined as the presence of endometrial tissue at ectopic sites. This condition is characterized by severe pelvic pain, dyspareunia, dysmenorrhea, and infertility. Endometriosis continue
SNP ANALYSIS OF ENDOMETRIOSIS CANDIDATE GENES
Embryonic cells use the Hedgehog signaling pathway to convey information that controls cell fate, proliferation, and survival. Misregulation of this pathway leads to birth defects and a variety of cancers in humans. Recent data point to key mec
HEDGEHOG SIGNALING AND INTRACELLULAR TRANSPORT
Executive functioning (EF) refers to self-regulation of thought and behavior. It has been implicated in several areas of cognitive and social development and deficits in EF are found in childhood disorders of autism and ADHD. Surprisingly littl
PSYCHOMETRICS /EXECUTIVE FUNCTION IN PRESCHOOL CHILDREN
We received notification of our grant award (grant # 3R01HD052074-03S1) on September 17, 2009. Since then we have contacted a sales representatives from Thermo Fisher Scientific, Nanodrop Products regarding the Nanodrop 2000 spectrophotometer.
GABAergic Dysfunction in Autism:Admin Supplement
The parent grant supports research to synthesize and analyze the major experimental early childhood intervention programs and non-experimental studies of family influence.  Three tasks were delineated in the original proposal:  (1) to put the i
Synthesizing and Interpreting the Evidence on Early Interventions
Congenital Diaphragmatic Hernia (CDH) is a frequent and often fatal developmental condition of diaphragm defects associated with lung hypoplasia caused by diverse factors that we hypothesize are predominantly genetic, but heterogeneous. Project
Gene Mutation and Rescue in Human Diaphragmatic Hernia
The supplement will provide detailed pharmaceutical data to determine if women who receive an epidural during delivery are at higher risk for premature breastfeeding termination or early supplementation with formula. The parent grant will use
COMMUNITY PARTNERSHIP FOR BREASTFEEDING PROMOTION AND SUPPORT: CREATING SYSTEM CH
The overall goal of the experiments performed in this laboratory are to identify the mechanisms controlling the activity of the hypothalamus-pituitary-adrenal (HPA) axis in fetal sheep. Providing a more complete understanding of the activity of
Renal Transporters and Fetal Neuroendocrinologhy
The purpose of this project is to examine how a group of low-income parents from New Orleans, most of whom are single African American women, have coped with the effects of Hurricane Katrina. The 1,019 low-income parents in our sample are part
ADVERSITY AND RESILIENCE AFTER HURRICANE KATRINA
: Undergraduate research experiences are essential to providing important skills and encouragement for students to pursue careers in the health related sciences. These opportunities are often very difficult for undergraduate students to obtain
ARRA SUMMER RESEARCH EXPERIENCE SUPPLEMENT FOR:
The inability to communicate underlies one of the most disabling aspects of injury to the central nervous system, and includes the inability to perform rudimentary tasks such as flexing and extending ones' limb or moving a simple cursor on a sc
Neuronal Based Prothestic Control of Volitional Movement
A General Bayesian Polymorphism Discovery Tool: This project is aimed at the creation of a computer software package that can be used for the discovery of single-nuclotide polymorphisms (SNPs) and short insertion / deletion type genetic variati
A General Bayesian Polymorphism Discovery Tool
The award supported summer research of undergraduate student. It was a great educational opportunity for students, which allowed hands-on laboratory research experience and active contribution to laboratory work. In addition the student was abl
Role and Regulation of Protein Kinase C Isoenzymes
While there are a number of surgical alternatives to autologous large diameter vascular grafts, i.e. allografts, xenografts, and synthetic vascular graft substitutes, there are no clinically acceptable alternatives to healthy autologous small d
EPC ADHESION TO TEFLON-AF AND EPTFE VASCULAR GRAFTS
The goal of this project is to structurally understand how the thromboxane A2 synthase (TXAS), coordinates (couples) with the upstream cyclooxygenase (COX) isoform-1 (COX-1) vs. isoform-2 (COX-2) in the biosynthesis of TXA2 (a key pro-thromboti
Prostaglandin I Synthase Thromboxane A Synthase and Prostaglandin E Synthase
The purpose of the requested supplement was to promote summer job creation for faculty from a non-research intensive institution.  The administrative supplement was awarded to Dr. Mary Russell, a science educator at the Trumbull campus of Kent
Propofol and Protein Kinase C: Molecular Interactions in Cardiomyocytes
This application proposes to continue our studies of the Na,K-ATPase and is directed toward several ongoing goals. One of these is to test whether the cardiac glycoside binding site of the alpha2 or alpha3 isoforms of this enzyme, which is high
DESCRIPTION (provided by applicant): Protein drugs are currently administered systemically by injections. For individuals requiring chronic therapy, self administration with a needle is an unpleasant everyday experience. Development of injectab
Protein Stability in Polymer Delivery Systems
. The identified educator (visiting scientist) will join our laboratory team, which conducts research into the structure and function of blood coagulation factor IXa. The work that will be involved with this summer research is directly related
Structural Mechanisms of Factor IXa Function
University of Texas Health Science Center at Tyler
The goal of this Administrative Supplement is to support the employment of additional laboratory personnel.  Increased support is needed to bolster our efforts to identify and characterize genes that regulate oxygen sensing, smooth muscle respo
Mechanisms of Ductus Arteriosus Regulation
The decline of contractility with ischemia - reperfusion is multifactorial. The parent grant, HL78845, aimed to define the root causes of the contractility decline by focusing on three specific aims: 1) To test the hypothesis that ischemia - re
Regulation of Contractility During Ischemia-Reperfusion
DESCRIPTION (provided by applicant): The long term objective of this work is to understand the mechanisms of genetically defined inherited cardiomyopathies in order to shed light on common mechanisms and devise therapies for cardiovascular dise
The reported association between an unfavorable fetal environment and adult diseases may be confounded by a genetic predisposition toward specific diseases (eg, vascular diseases) as the maternal genes that are transmitted o the fetus may also
IN UTERO PROGRAMMING OF ADULT VASCULAR FUNCTION
In this Administrative Supplement, we will examine the potential role of PECAM1 in fluid shear stress-mediated VEGFR2/Gab1/eNOS signal pathway, which is involved in flow atheroprective effects.
RECEPTOR TYROSINE KINASES IN MECHANOTRANSDUCTION
This is an administrative supplement to the parent R01. We propose to study a refined approach for quantification of contractile function of the heart. The supplement is expected to increase the tempo of scientific research and create one job p
IMAGING STEM CELL GRAFTED IN THE INFARCTED MYOCARDIUM
The main objective of the parent grant is to understand the relationship between sleep disordered breathing (SDB) and excessive daytime sleepiness in patients with obstructive sleep apnea hypopnea syndrome (OSAHS), at baseline and following the
Relating sleep disordered breathing to daytime function.
In the United States, homeless people number at least four million, a figure that is currently growing rapidly due to the recent rise in mortgage foreclosures across the nation.  Despite progress made in reducing cigarette smoking in the genera
Improving Varenicline Adherence and Outcomes in Homeless Smokers
This project award will retain a pre-doctoral graduate student (FTE). The overall aim of the parent grant (PG, HL081682) proposal is to determine the mechanisms by which calcium (Ca) signaling differentially regulates vascular smooth muscle cel
Calcium-dependent Regulation of Smooth Muscle Phenotype
Aim 1 of the parent grant focused on characterizing the regulation and localization of several catenin proteins as a function of the hemodynamic environment in vitro and in vivo in the context of atherosclerosis.  One of our major observations
Hemodynamic Adaptation of Intercelluar Junctions in Human Endothelium
The aims of this supplement are to to determine if genetic variation in thromboxane synthase, ET-1, or Rho-kinase determine six minute walk distance and response to therapy in PAH.     Samples are undergoing genetic and statistical analysis cur
A Clinical Trial of Aspirin and Simvastatin in Pulmonary Arterial Hypertension
The purpose of this grant is to elucidate the regulation of mitochondrial turnover by O-GlcNAc signaling.  Because O-GlcNAc is a metabolic signal, it may affect mitochondrial abundance during pathologic events, such as myocardial infarction (is
Metabolic Mechanisms of Cardiac Injury and Protection
Effect of Adenosine A2 receptor activation on the mitochondrial death pathway (A The main purpose of the supplement is to characterize the exact role of zinc released during reperfusion in the cardioprotective effect of A2 receptor activation i
Effect of Adenosine A2 receptor activation on the mitochondrial death pathway (A
Intracranial aneurysms are abnormal dilations of brain arteries that may rupture in some patients causing stroke and possibly death. Some treatment modalities are available, but they carry risks to patient health and hence best performed only o
Assessment of intracranial aneurysm shape as an indicator of rupture risk
Pathobiology of HIV(SIV)-Induced Angioproliferative Pul*
We requested funds to hire a new staff member to assist us in adding polysomnography (sleep recording) and sleep scoring to these studies.  This will expand the scope of the studies in the original grant.  This new staff member will gain experi
Sleep Length and Circadian Regulation in Humans
LOVELACE BIOMEDICAL & ENVIRONMENTAL RESEARCH INSTITUTE INC
The broad long-term objectives of the application are to determine the mechanisms by which the Severe Acute Respiratory Syndrome (SARS)-associated coronavirus (SCoV) causes acute lung injury and to identify new therapeutic strategies. The centr
SARS CORONAVIRUS VIRULENCE FACTORS AND LUNG PATHOGENESIS
The student will participate in testing how different PAR agonists differentially regulate barrier function using ECIS in an endothelial cells as a model. We will further explore the ability of different PAR agonists to differentially regulate
Regulation of Vascular Permeability by Thrombin Medicated Signaling Pathways
The parent application for this administrative supplement focuses on the mechanism by which inhaled carbon monoxide (CO) exerts its therapeutic actions in the mouse model of experimental pulmonary hypertension. In the process of conducting rela
Role of Caveolin-1 and eNOS in Mediating the Therapeutic Effects of CO in PAH
Idiopathic pulmonary fibrosis (IPF) is characterized by fibroblast and myofibroblastic foci, and has excessive extracellular matrix protein accumulation. Focal-adhesion-kinase-related-non-kinase (FRNK) mediates integrin-mediated cell migration.
THE ROLE OF FAK-RELATED-NON-KINASE (FRNK) IN LUNG FIBROSIS
There is considerable interest in the mechanisms underlying the regulatio of transalveolar fluid clearance. The main goal of the parent grant is to study the contribution of the cGMP-activated ä ENaC-containing channels to transepithelial salt
Regulation of lung epithelial sodium channels by cGMP
The primary aim of the project, as mentioned in the parent grant proposal (1R01HL087795-01A1), is to utilize an ontology?]driven problem solving environment (PSE) for the human pathogen Trypanosoma cruzi.  The PSE will enable the identification
Semantics and Services Enabled Problem Solving Environment for Trypanosoma cruzi
The treatment with cardiovascular medical devices enhances survival for many patients with otherwise hopeless medical conditions. Unfortunately, in many cases these devices cause dangerous pathological complications, in particular thrombosis an
Linking Multiscale Dynamics of Shear-induced Blood Damage to CFD modeling
To develop a reproducible, bioreactor-based system to expand and differentiate adult bone marrow and skeletal muscle-derived side population (SP) stem cells to determine their regenerative and reparative potential.
Expression and Directed Differentiation of Adult Side Population Stem Cells
Intimal hyperplasia, which is caused by proliferation and migration of smooth muscle cells (SMCs), contributes to restenosis (the re-occlusion of vessels) after arterial reconstruction. We have recently found that carotid artery injury results
Role for S1P2 in the Arterial Injury Response
This supplement will advance our scientific discovery by accelerating data analyses on a funded-study involving approximately 620 adolescents, assessed in infancy, 3 to 5 years and 10 years as part of a NIH-supported cohort study of the behavio
BIOPSYCHOSOCIAL DETERMINANTS OF ADOLESCENT OBESITY/CARDIOVASCULAR RISK
Mammals that hibernate depress their metabolic, heart and respiratory rates, as well as their core body temperature (Tb) to enter a state called torpor. In hibernators such as ground squirrels, torpor is precisely controlled and fully reversibl
Biomarkers for the two phase switches of mammalian hibernation
This proposal seeks supplemental funding through the Recovery Act to extend the Specific Aim #2 of the parent grant. Our long-term objective is to elucidate the endocytic trafficking pathways of the Cystic Fibrosis Transmembrane Conductance Reg
Regulation of the Endoytic Trafficking of CFTR
This application raises the possibility that the myocyte compartment of the embryonic, fetal and post-natal heart is generated by activation and lineage commitment of a pool of resident c-kit-positive cardiac progenitor cells (CPCs) which are c
The second and third aims focused on two potential mechanisms that may restrict post-transcriptional activation of Ets within heart founder cell progeny; A) exposure to different levels of FGF (the gradient model) or; B) differences in the ab
SIGNALING PATHWAYS IN EARLY HEART DEVELOPMENT
This administrative supplement provides an opportunity for Dr. Manjunath Harlapur, a post-doctoral fellow, to receive high quality training in conducting patient-oriented translational research in the area of preventive cardiology. Dr. Harlapur
Cardiovascular Disease: Depression and Telomere Length - Administrative Supplement
through the measurement of circulating levels of endothelial cell biomarkers as well as direct visualization of microcirculatory flow with in-vivo videomicroscopy. Accordingly, the broad, long-term objective of this project is to study the rol
ENDOTHELIAL CELL SIGNALING AND MICROCIRCULATORY FLOW IN SEVERE SEPSIS
cDNA microarrays are a powerful tool to uncover genetic mechanisms underlying any condition. A major limitation is that the microarrays are not designed for rare species, such as in this grant, hibernating woodchucks.  Accordingly this suppleme
Mechanisms of Intrinsic Cardioprotection in Marmota momax
The incidence of congenital heart disease, including heart valve abnormalities, is approximately 1% of live births, and structural anomalies of heart valve leaflets and supporting structures are commonly observed. Mature heart valve structures
MOLECULAR REGULATION OF HEART VALVE DEVELOPMENT AND FUNCTION
The challenges of warfarin therapy are significantly greater among patients with chronic kidney disease (CKD) and ESRD compared to that among patients with normal renal function. CKD can significantly reduce non-renal clearance and alter the bi
GENETIC AND ENVIRONMENTAL DETERMINANTS OF WARFARIN RESPONSE
Sepsis affects more than 300,000 individuals in the US annually, costs more than $16 billion/yr to treat, is associated with an acute mortality of 30%, and is expected to increase in incidence, making this disease a major public health concern.
Mutation in the gene for the ABCA3 transporter cause a variety of lung diseases that result in either death in the immediate newborn period or chronic lung disease in children and into adulthood.  We have created mouse models of the human ABCA3
ABCA3 and Response to Lung Injury - ARRA Stimulus Funding - Diversity Suppl
Description (provided by the applicant): Coagulation factors V (FV) and factor VIII (FVIII) are both secreted glycoproteins that share pivotal roles in both hemostasis and thrombosis. Although many secreted proteins (referred to as cargo) are b
ER-TO-GOLGI TRANSPORT OF COAGULATION FACTORS V AND VIII
Arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) is a genetic form of cardiomyopathy, which is typically characterized by right but also recently left ventricular dysfunction, fibrotic/fatty replacement of the ventricle and ve
THE MOLECULAR MECHANISMS UNDERLYING ARRHYTHMOGENIC RIGHT VENTRICULAR DYSPLASIA/CA
The parent grant of this application is focused on 1) determining the mechanisms mediating the repsonses to stimulation of NTS adenosine receptor subtypes and 2) the role of adenosine receptors in NTS in modulating cardiovascular responses from
NTS ADENOSINE RECEPTORS IN CARDIOVASCULAR CONTROL
In this administrative supplement request, we propose to accelerate a subset of our proposed tasks for this grant.  In particular, we propose to:   1.  Accelerate the software engineering activities in creating a reference implementation of FEA
ANNOTATING FUNCTIONAL SITES IN 3D BIOLOGICAL STRUCTURES
National Oceanic and Atmospheric Administration
Provide and install a new Heating, Ventilating and Air Conditioning (HVAC) system at the Pacific Fisheries Environmental Laboratory, Southwest Fisheries Science Center, Pacific Grove, CA
Automatic Environmental Control Manufacturing for Residential, Commercial, and Appliance Use
Biologist support services.  Support services will satisfy the overall operational objectives of promoting the protection, conservation, and recovery of salmons and their habitat.  The primary objective is to provide services and deliverables t
INSTITUTE FOR INDIAN DEVELOPMENT INC, THE
WIA Youth Activities-Native Americans: To provide summer youth employment to Native American youth from Federal Recognized tribes who are economically disadvantaged and are between the ages of 16-21. The purpose of the summer employment is to p
To provide ARRA youth employment opportunities and work readiness skills training to Indian and Native American youth.
To provide summer youth employment opportunities, work readiness skills training and year-round services to Indian and Native American youth under Section 166 of the Workforce Investment Act
To provide summer youth employment opportunties, work readiness skills training and services to Native Americans
ABSENTEE SHAWNEE TRIBE OF OKLAHOMA, INC., THE
ARRA Supplemental Youth funding is awarded to Native American Youth between the ages of 14 and 24 to acquire the educational skills, traning, and the support needed to achieve academic  and employment success and successfully transition to care
To provide summer youth employment opportunities, work readiness skills training and year-round services to Indian and Native American youth under Section 166 of the Workforce Investment Act.
Seminole Nation of Oklahoma Summer Youth Work Experience
To provide summer youth employment, iopportunities, work readiness skills, training to Indian & Native American Youth under Sec. 166 of the Workforce Investment Act.
To provide summer employment and work readiness to Indian and Native American Youth under Section 166 of the Workforce Investment Act program.  The Ute Indian Tribe covers expenditures and is reimbursed for expenses at the end of the quarter.
Ute Indian Tribe/Workforce Investment Act
To provide summer youth training opportunities to eligible youth, and develop work readiness skills training, life skills, and financial skills training to help youth inter act with the workforce and provide year round services to  Native Ameri
Puyallup Tribe Summer Youth Employment and Training Program.
To provide summer youth employment opportunities, work readiness skills training and year-round services to Indian and Native American youth.  The Tribe operates on a reimbursement basis and does submit for reimbursement monthly.
CALIFORNIA INDIAN MANPOWER CONSORTIUM, INC.
SYS ARRA Program to provide summer youth employment opportunities, work readiness, and year-round services to Indian and Native American youth under Section 166 of the Workforce Investment Act.
LABOR AND INDUSTRY, MONTANA DEPARTMENT OF
The ARRA Senior Community Service Employment Program (SCSEP) will provide subsidized, part-time training opportunities in community service for low income people 55 years of age or older.
Current SCSEP grantees will use the ARRA funds to support additional training and employment opportunities for unemployed low-income seniors.  Grantees will expand the number of SCSEP participants assigned to community service work, especially
Senior Community Service Employment Program (SCSEP) AD 18399-09-60-A-53 $350,475 awarded, $340,866.25 expended, CFDA 17.235, 0 jobs created.   To provide subsidized, part-time, community service work-based training for low-income persons age 55
Community Service Employment Funded Through the Senior Community Service Employment Program Authorized by the Older Americans Act
Experience Works Senior Community Service Employment Program (SCSEP) provides subsidized, part-time, community service work-based training for low-income persons age 55 or older who have poor employment prospects.
Community Service Employment Funded Through the Senior Community Service Employment Program Authorized by the Older Americans Act.
1.	National Able Network?s modified slot count for ARRA was originally 151.  By the close of the program year, Able had placed 211 SCSEP Participants in community service training assignments in the states of Maine, Massachusetts and New Hampsh
Senior Community Services Employment Program (SCSEP)
NATIONAL CAUCUS AND CENTER ON BLACK AGED, INC.
To provide subsidized, part-time, community service work-based training for low income persons age 55 or older who have poor employment prospect.
Title:  Senior Community Service Employment Program (SCSEP), American Recovery and Reinvestment Act (ARRA) of 2009.  Description:  In accordance with Title V of the Older Americans Act, SCSEP provides part-time temporary paid employment to unem
SER-Jobs for Progress National (SER National) through funding provided by the American Recovery and Reinvestment Act of 2009 (Recovery Act) is to provide services in partnership with the current SER National SCSEP Program Partners to adminster
S & S GENERAL CONTRACTORS & EQUIPMENT RENTAL, INC.
Install two government supplied bridges on USFS roads in Southeast Alaska
wide to water treatment room door. Propane Piping: Upgrade 80 lf propane piping. Install proper propane flex connectors to stove, water heater, refrigerator, freezer, and 2 bedroom heaters. Water Heater Stack: Replace stack on water heater and
USDA, Office of the Chief Financial Officer
This is the 1st part of the 4th Phase of a multi-phase renovation program for the modernization program for the South Building of the US Department of Agriculture, Washington DC.  The purpose is to provide updated, safe, comfortable and accessi
USDA, Office of the Chief Information Officer
Other Computer Peripheral Equipment Manufacturing
PROVIDE PROCUREMENT ACQUISITION SUPPORT SERVICES FOR USDA FOREST SERVICE WASHINGTON, DC
ADVANCED ENVIRONMENTAL MANAGEMENT GROUP, LLC
Pre Acquisition Environmental Database Records Search
Design of rehabilitation measures for a multi-purpose dam to increase flood carrying capacity and provide downstream scour/erosion protection.  Project will involve field surveying, engineering, and design activities to develop documents (drawi
Bailey Edward architecure was contracted to conduct a Pre-Design study related to the repair of the exterior brick and re-sealing of the windows at teh reasearch facility in Madison.
A-E design, bid phase and construction phase services to repair/replace the 100-Ton Air Conditioner and Cooling Tower with Aircooled Chiller and associated piping for the Harned Building located at the ARS Research Facility located in Starkvill
Akron USDA/ARS Bldg 1 HVAC Repairs - Design Services.
Replace Air Distribution system at the Appalachian Fruit Research Station, Kearneysville, WV
Prepare landline contracts for trail & trail bridge maintenance
clean crushed aggregate to be supplied and tailgate spred on various roads on the Fredericktown Ranger District on the Mark Twain National Forest in Missouri.
This project involved structural analysis and design for the resoration of Historic Red Bridge
Surface blading (road grading) on Mark Twain Forest
RECOVERY - CELINA DAM ACCESS ROAD MAINTENANCE PROJECT.
Chemically treat kudzu with boardcasy spraying equipment
Archaeological review and Section 106 documentation for proposed ARRA trail maintenance projects.
perform land line surveys for wildland fire management at Francis Marion National Forest
SWIFT & STALEY MECHANICAL CONTRACTORS, INC.
REPAIR DAMAGE TO ROADS AND TRAILS, DUE TO THE ICESTORM AT LAND BETWEEN THE LAKES NATIONAL RECREATION AREA.(MOD 5 DEOBLIGATED $6904.34 9/26/11)
Baldwin RD Mast Lake Fuels Cadastral Survey
Survey of Wetland Reserve Program Easement
MARTIN & WHITACRE SURVEYORS & ENGINEERS, INC.
The nature of work under this task consists of Expert Resident consultant functions performed on-site in support of the installation, training, configuration, and successful deployment and effective use of the Precise i3 Application Performance
minus aggregate on the Apache National Forest, Springerville District at Rolfe C. Hoyer Campground, Greer, AZ.
FUEL REDUCTION ACTIVITIES ON BITTERROOT NATIONAL FOREST. * HELICOPTER YARDING * LEAVE TREE PROTECTION * LIGHT SLASHING
RECOVERY PROJECT FOR REPLACEMENT OF LABORATORY FACILITIES? HVAC SYSTEMS AND COMPONENTS at the Red River Agricultural Research Center 1605 Albrecht Blvd. in Fargo, N.D.
Big Horn WUI Fuels Treatment IDIQ Pussyfoot Thinning-Slashing Yard & Pile
Manufacture, deliver and install 21 prefabricated, precast concrete restroom buildings in the Pike San Isabel National Forest.
2009 CLRD and South Zone Tree Thinning and timber Stand Improvement Projects.  Support activities for forestry.
fusion proteins. Understanding the molecular mechanism of class II membrane fusion will provide insights into virus disease mechanisms, enable the design of specific antiviral therapies, and advance our knowledge of viral and cellular membrane
MOLECULAR ANALYSIS OF ALPHAVIRUS MEMBRANE FUSION PROTEIN
Food allergy (FA), a condition caused by an immunoglobulin (Ig) E-mediated hypersensitivity reaction to food, is a growing clinical and public health problem in the U.S. and worldwide.  FA affects approximately 5-8% children and 1-4% of adults.
Genome-Wide Association Study of Food Allergy
Airport Development for New Hampshire Block Grant (ARRA 2009) including funds for the following locations/projects:  Laconia Municipal Airport to rehabilitate the terminal apron in the amount of $835,420; Dillant-Hopkins Airport to rehabilitate
New Hampshire Block Grant (ARRA 2009) including funds to rehabilitate aircraft parking aprons at the following locations:  Laconia Municipal Airport; Dillant-Hopkins Airport; and Nashua Airport - Boire Field.
Project is to close old landfill and open new as the old site is in danger of eroding into the Yukon River and leachate from the old site enters the Yukon river which is the source for drinking water for several communities.  Project will inclu
The Fairbanks North Star Borough is investing in Public Transportation by making various capital purchases to include bus enunciators, a new bus wash, security cameras for our paratransit vehicles and fixed route buses, gates at our maintenance
09 ARRA 5307 Vans (4), P&R, ADA Fac, equip
Bus and Other Motor Vehicle Transit Systems
Construction Contract with Capstone Construction. Contractor started work on August 9, 2010 and is complete
Initial installation of HVAC and window/security screens at selected sites.
Conduct modernization activities at various Public Housing developments.  This funding can be expected to result in providing employment for architects, construction workers and product manufacturers.  In addition this funding can be expected t
FUQUA AND WALDING MANAGEMENT SERVICES, INC.
These apartments consists of 28-1BR and 8-2BR Section 8 Apartments
Rental assistance for HUD 202/Section 8 housing
EPA provided IHS $317,211 of Drinking Water Infrastructure Grants Tribal Set Aside funds through Interagency Agreement DW-75-95766001-0 for this project.  Project scope: This project will replace degraded water mains in the Canada area in McCar
Midtown Apartments consists of 8-1BR and 8-2BR Section 8 Apartments.
HHA plans to do modernization work at various Public Housing communities.  This grant will also provide funding for fees and costs and relocation associated with another project where funding was not available in another grant.
ARRA Capital Fund Public Housing Modernization Program
Conduct Modernization activities in PHA Units.  This funding can be expected to result in providing employment for architects, construction workers and product manufacturers.
HOUSING AUTHORITY OF REFORM, ALABAMA, THE
Conduct modernization activities.  This funding can be expected to result in providing employment for architects, construction workers and product manufacturers.  In addition this funding can be expected to modernize the units.
Conduct moderization activities at various Public Housing developments.  This funding can be expected to result in providing employment for architects and engineers, construction workers and product manufacturers.
Conduct modernization activities. This funding will result in providing employment for architects, construction worker and product manufactures.
Contract awarded for modernization of existing low income housing units.
The Scottsboro Housing Authority is implementing the following activities using Capital Fund Recovery Act funding: 166 units of the SCOTT/HUNTER HOMES ADDN (AL099000001) public housing development are being rehabilitated; 20 units of the PLEASA
HOUSING AUTHORITY OF THE CITY OF PIEDMONT ALABAMA INC, THE
Remove & replace all existing windows & screens. Remove all outside hose bibs & recess them under lock boxes for the maintenance department since we pay the water in this property.
Conduct modernization activities. This funding can be expected to result in providing employment for architects, construction workers and product manufacturers.  In addition this funding can be expected to modernize units including rewiringk ga
Money will be used in modernization of elderly units to put in energy efficent HVAC, replacement of windows and doors with energy ones
Public Housing Capital Fund Stimulus (Formula)Recovery Act Funded
HOUSING AUTHORITY OF THE CITY OF DALEVILLE ALABAMA , THE
Modernization activities of the Public Housing Units; This funding will result in providing employment for general contractors & some specialized contractors.
HOUSING AUTHORITY OF GREENE COUNTY, ALABAMA
544-(combo loan and grant)water only-09/10 Stimulus
7/14/2010- Grant Amendment No. 1: Grant amendment no. 1 programs remaining ARRA Section 5307 Federal Funds in the amount of $1,023,565.00 to further the activities outlined in the initial grant application. This grant amendment included $493,56
ALASKA NATIVE TRIBAL HEALTH CONSORTIUM INC
EPA provided IHS $3,151,040 of Clean Water Act Indian Set Aside funds through Interagency Agreement DW-75-95765901-0 for this project.  Project scope: Complete construction of new sewage lagoon and force main.
EPA provided IHS $146,340 of Clean Water Act Indian Set Aside funds through Interagency Agreement DW-75-95765901-0 for this project.  Project scope: Replace existing shallow buried sewer mains to eliminate freeze failures.
American Reinvestment & Recovery Act Equipment (NR) +35,000 for Colposcope with digital camera for magnification & documentation and laptop computer and monitor.
To purchase five dental chairs, freight and the installation of the five chairs by the bio-med team with the Alaska Tribal Health Consortium.
The International Trans Antarctic Scientific Expedition (ITASE) was formed with the goal of understanding the past 200-1000+ years of physical and chemical climate over Antarctica and adjacent reaches of the Southern Ocean. ITASE has resulted i
ARRA: Collaborative Research: Antarctic Climate Reconstruction Utilizing the US ITASE Ice Core Array (2009-2012)
This project will construct a geomagnetic paleointensity record from the Shaldril NBP05-02 sediment core collected from Maxwell Bay, Antarctic Peninsula.  This core contains the rare combination of a strongly-magnetic silty-clay lithology and c
Enhancing Holocene Ice Sheet and Ice Shelf Geochronology using Geomagnetic Paleointensity Variations
Global climate change is altering polar marine ecosystems through rising temperatures and ocean acidification. Benthic communities in Antarctica face an additional threat: the unprecedented, climatically driven invasion of predators from temper
COLLABORATIVE RESEARCH CLIMATE CHANGE AND PREDATORY INVASION OF THE ANTARCTIC MARINE ENVIRONMENT
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). The RAGES project (Robotic Access to Grounding zones for Exploration and Science) is one of three research components of the WISSARD (Whillans Ice
Collaborative Research: Integrative Study of Marine Ice Sheet Stability and Subglacial Life Habitats - Robotic Access to Grounding-zones for Exploration and Science (RAGES)
The Ross Sea is a highly productive area within the Southern Ocean, but it experiences substantial variability in both physical (temperature, ice concentrations, salinity, winds and curent velocities) and biogeochemical (chlorophyll, productivi
This award supports a project to make continuous major ion analyses in the West Antarctica Ice Sheet Divide (WAIS Divide) ice core by sampling the brittle ice zone (approximately from 500 m to 1500 m). The intellectual merit of the project is t
Major Ion Chemical Analysis of Brittle Ice in the WAIS Divide Ice Core
Ironwood Drive - US 60 to Southern Resurfacing and Reconstruction
FIRST PRESBYTERIAN CHURCH CHILD CARE CENTER, INC.
Two (2) police cruisers and four(4) taser guns
Replacement of windows in family development with energy efficient windows and upgraded to a master key lock system.  Also addition of new kitchen cabinets.
HOUSING AUTHORITY OF THE CITY OF MAGNOLIA, THE
HOUSING AUTHORITY OF THE CITY OF NEWPORT (AR028)
The Housing Authority of the City of Newport is implementing the following activities using Capital Fund Recovery Act funding:  264 units of the NEWPORT (AR028000001) public housing development are being rehabilitated.
HOUSING AUTHORITY OF THE CITY OF HOT SPRINGS, THE
Rehabilitation/modernization of apartments at various locations.
Funds were used for the modernization activity at the Imboden Public Housing.
Housing Authority of The City of Imboden
remodeled 17 bathrooms, removed trees on Kelly street and Replaced water valves
HOUSING AUTHORITY OF THE CITY OF CROSSETT
The Housing Authority of the City of Crossett is implementing the following activities using Capital Fund Recovery Act Funding: bathroom renovations, kitchen renovations, interior/exterior improvements, ranges, refrigerators, exterior and inter
Our parent grant, entitled “Answering Information Needs in Workflow”, proposes to explore technologies to help clinicians articulate information needs that arise during clinical practice, and address them in a timely manner that fits with c
Knowledge of protein function serves as a corner stone for biomedical research, which is fundamental for understanding biologic systems, the mechanism of disease and ultimately the human health.  Decades of biomedical research has accumulated a
Automatic Literature-Based Protein Annotation - Administrative Supplement
As new technologies such as virtual microscopes, multi-spectral imaging, and antibody-conjugated quantum dot probes (QD) continue to gain acceptance we have capitalized on the modular, flexible design of the imaging tools that we are developing
IMAGE MINING FOR COMPARATIVE ANALYSIS OF EXPRESSION PATTERNS IN TISSUE MICROARRAY
The principal objective of this project is to develop methods that combine pathogen genotyping and patient epidemiology data that can be used in the control, understanding, and tracking of infectious diseases.
Discovering Hidden Groups Across Tuberculosis Patient and Pathogen Genotype Data
Neurophysiological Studies of Schizophrenia: Translational Science: Innovative Targets and Models for Developing Treatments for Mental Disorders. The overall goal is the creation of an in vitro animal model of high frequency (gamma band; approx
DESCRIPTION (provided by applicant): This application is the first competitive renewal of a project designed to understand the effects of abuse on children's brain-behavioral development. Studies of non-human animals have shown that adverse par
Emotion processing: Risk for psychopathology- Diversity Supplement
Schizophrenia is currently thought to be a complex genetic disorder, with early developmental abnormalities in brain structure and function, being important in determining vulnerability to illness. This study will examine changes in smell abili
Olfactory Function in Schizophrenia: A Lifespan Analysis
the sources of functional input to a single neuron. Combining this method with paired intracellular recordings and cross-correlation analyses of postsynaptic currents allows identification of shared inputs on a fine scale. Results from these s
Local Connections of Inhibitory Cortical Neurons
The parent grant is focused on identifying cognitive and neural components of working memory (WM) deficit, a core feature of schizophrenia (SZ).  Since WM deficit is linked to poor social functioning and outcome, it is very important to develop
Etiology of Working Memory Deficit in Schizophrenia
The overall objective of the present proposal is to develop, evaluate, distribute, and apply tools for quantitative meta-analysis of the human functional brain mapping (HFBM) literature. The BrainMap database may be used as an internet-based re
This competitive revision is to enlarge the scope of the current R01 - ‘Dysfunctional Corticolimbic Activity and Connectivity in Bipolar Disorder' to also study at baseline 20 bipolar disorder (BD) patients in the euthymic state (BDE) and 40
Endophenotypic Role of Corticolimbic Activation and Connectivity Abnormalities in Bipolar Disorder
This proposal describes a rational system for the identification of genes that controlnaturally occurring variability for fear conditioning (FC) in mice using a quantitative trait locus (QTL) mappingstrategy. As QTL strategies and technologies
FINDING GENES THAT CAUSE QLT FOR FEAR LEARNING AND ANXIETY
The ARRA award provides supplemental funds to an existing research grant, ?Effectiveness Of A Depression Care Management Initiative In Home Healthcare? (R01 MH082425, PI: Martha L. Bruce).  The goal of the research is to improve depression trea
Effectiveness of a Depression Care Management Initiative in Home Healthcare
Our principal objective is to identify genetic variation that underlies liability to schizophrenia and other psychotic disorders (henceforth called Scz) in the Oceanic population of Palau. We will accomplish this goal by capitalizing on a wide
ARRA: Genetics of Schizophrenia in Oceanic Palau
Chemotherapy, Pain, Sleep, Fatigue in Children and Parents Symptom management is a critical issue in both acute and chronic illness care. Studies with adults repeatedly demonstrate the deleterious effects of symptoms on health outcomes such as
Chemotherapy, Pain, Sleep, Fatigue in Children & Parents
mechanism in the SDH to modulate the development and persistence of nociception induced by NRTIs, and we will explore this in detail in this proposal. Lay language: A common problem for people with HIV is severe pain in the legs caused by thei
BDNF Signal Strength Modulates NRTI-Induced Allodynia in the Mouse
This grant provides a summer research experience for one undergraduate student in health-related scientific research.
Award description: A fundamental question in neuroscience is to understand how inputs from our hands, eyes and ears are processed in the central nervous system. At the input level for each sensory system are arrays of receptors that are sensiti
CORTICAL PROCESSING OF TACTUAL SPACIAL INFORMATION
Brain becomes more resilient to injury through activity, including that from spreading depression (SD). While, mechanisms for this intrinsic process remain undefined, they involve innate cytokines. Importantly, innate cytokines are redundant an
Molecular Studies of Spinocerebellar Ataxia Type I
Nicotinic acetylcholine receptors (nAChRs) are essential to behaviors as basic as breathing and as mysterious as motivation, memory and mood. Loss of cholinoceptive sites, evident as decreased nAChRs and deterioration of central cholinergic pro
ARRA:  Expression of Neuronal Nicotinic Acetylcholine Receptors
UMDNJ-ROBERT WOOD JOHNSON MEDICAL SCHOOL
Administrative Supplement for a Summer Undergraduate Student for RO1 NS032401, “PACAP Regulation of Neurogenesis and Survival” (PI: E. DiCicco-Bloom).  I requested this supplement so that we may 1) accelerate the tempo of scientific researc
PACAP Regulation of Neurogenesis and Survival
The neuronal ceroid lipofuscinosis (NCLs) are recessively inherited childhood disorders, with an incidence of approximately 1:12,500 in the U.S. NCL is a problem of selectively impaired mitochondrial autophagy, as neuronal cells in the CNS feat
The overarching goal of this award was to examine the effects of lesions to specified areas in posterior parietal cortex.  We examined the effects of lesions to area 5 on two well defined manual and bimanual behaviors, as well as the effects th
Subproject for Institution # 960426: Somatosensory Cortex and Thalamus
Songbirds provide an animal model for human speech perception and production, and for developmentally restricted forms of learning and memory, in which it is possible to causally link specific behaviors and their underlying neural circuitry. Bi
Mental retardation is a prominent clinical feature of the lysosomal storage disorders (LSD's), due to the severe pathology in the central nervous system (CNS). The LSD's constitute a significant number of the human genetic diseases that affect
Thalamic injury has been poorly investigated in mild traumatic brain injury (MTBI). The thalamus is important to communication among many associative brain regions including sensory, motor, cognitive, and behavioral functions; it is one of the
Quantitative MRI and 1H-MRS Traumatic Brain Injury
Our currently funded studies from NINDS were designed to test the overall hypothesis that rapid rotations of the immature brain (as associated often with abuse, motor vehicle accidents and falls) produce brain injury via both mechanical and bio
Regulatory T cells (Tregs), a special subset of T cells, serve as a primary regulator for immune response. The major function of Tregs is to oppose and control Th1, Th2 and Th17 cells. Here we will test a novel hypothesis that in addition to co
Activation of NF-kB in glial cells and CNS of EAE
The overall goal of the parent grant is to perform cognitive neuroscience experiments using electrocorticographic ECoG recordings in human subjects (EEG recorded from the brain surface with electrodes surgically implanted for epilepsy surgery).
ELECTROCORTICOGRAPHIC STUDIES OF HUMAN CORTICAL FUNCTION
This award is intended to provide (1) a summer research experience for an undergraduate student with an interest in pursuing a career in neuroscience and to accelerate the tempo of work on the parent grant.  The hypothesis of the parent proposa
RECIPROCAL SIGNALING BETWEEN SYNAPSES AND ASTROCYTES
Temporal lobe epilepsy (TLE) with mesial temporal sclerosis (MTS) is often associated with a history of febrile seizures (FC). However, the proposed causal relationship between FCs and MTS remains controversial. Identification of children at hi
Consequences of Prolonged Febrile Seizures in Childhood
The competitive award was requested to explore the role of mitochondria in HIV neuropathy and specifically the interaction between HIV envelope protein gp120 and mitochondrial function in causing distal axonal degeneration. We have already obta
This award is issued in response to Notice OD-09-060, Recovery Act Administrative Supplements Providing Summer Research Experiences for Students and Science Educators. DESCRIPTION (provided by applicant): The specification of cell types in the
GENETIC ANALYSIS OF MOUSE NERVOUS SYSTEM DEVELOPMENT
Viral-induced encephalitis remains a major cause of morbidity and mortality throughout the world. Effective therapies are available for only a few neurotropic viruses, and even when these infections are optimally treated, residual mortality and
Mechanisms of Apoptosis in the central nervous system
Our research program is toward the understanding of molecular basis of myelin regeneration and repair after injury in the central nervous system.  This critical event is facilitated by specialized cells called oligodendrocytes, which insulate a
Olig2 in Oligodendrocyte Myelination and Remyelination-ARRA Stiumlus Admin Suppl
We are requesting an Administrative Supplement to our Grant ?Neurotoxins from Marine Algae and Cyanobacteria? (NS053398) so as to increase the pace and tempo of the research on aims previously approved in peer review.  The broad, long term obj
NEUROTOXINS FROM MARINE ALGAE AND CYANOBACTERIA
Scripps Institution of Oceanography 9500 Gilman Dr
This administrative supplement is slated for upgrading a spinning disk confocal microscope for live cell imaging.  So far, we have purchased from Morrell Instrument Company a 60x Nikon lens ($10,020), which will allow us to visualize the entire
Structural Basis of CA2+ channel function and regulation
In addition to their bioenergetic function, mitochondria are critical regulators of Ca signaling in neurons. Mitochondria efficiently buffer Ca2+ influx during excitation and limit the amplitude of the cytosolic Ca2+ concentration ([Ca2+]i) inc
Mitochondrial Calcium Cycling in Neuronal Function
Molecular Pathogenesis Studies of Rett Syndrome
Title: Combination therapy in human ES cell transplantation after neonatal stroke Embryonic stem cell transplantation has been widely investigated as a novel therapeutic strategy in ischemic stroke. The original Specific Aims address three key
COMBINATION THERAPY IN HUMAN ES CELL TRANSPLANTATION AFTER NEONATAL STROKE
Among the billions of neurons and glia in the vertebrate central nervous system (CNS) is a rich milieu of extracellular matrix (ECM) proteins. Most CNS cells interact with ECM components via members of the integrin family of cell surface adhesi
ANALYSIS OF ALPHAVBETA8 INTEGRIN IN GLIOMAGENESIS
Spinal cord injuries with consequent paralysis affect more than 250,000 people in the US and several million worldwide. The biological causes that prevent axonal regeneration to occur in the central nervous system (CMS) are still elusive. The l
FEMTOSECOND LASER AXOTOMY FOR IN VIVO NERVE REGENERATION STUDIES IN C. ELEGANS
The goal of this proposal is to understand the role of the Sen1 helicase in termination of RNA Polymerase II (PolII) transcripts and to establish how mutations in the human homolog of Sen1, Senataxin (SETX), cause the neurodegenerative disorder
Pathogenesis of Neurodegenerative Diseases Caused by Mutations in Senataxin
There are persistent questions regarding the evolution and function of the immune system. Previously studies performed in non-mammalian vertebrates have helped to reveal basic features of the immune system that are universal. In other cases, st
The goal of this proposal is to determine the biological mechanisms that regulate male-typical sexual partner preference, and, thereby, to develop a better understanding of mammalian sexual differentiation and psychosexual development. The succ
This research proposal is a revised R01 application in response to the Program Announcement 'Continued Development and Maintenance of Bioinformatics and Computational Biology Software' for five years of funding to continue development and maint
Bioinformatics Software for MRI of Brain Development
flow cell (for bio-mineralization study) and a small-volume solution cell (for precious bio-materials), will be assembled and initially tested at Stony Brook, and then incorporated into the X27C beam line in the National Synchrotron Light Sour
ARRA: Instrumentation Development on Multi Scaled Scattering for Bio Molecular Solution
Researchers in bioinformatics and computational biology (BCB) continue to require virtually unbounded high performance computing (HPC) capability:  New scientific insights emerge with each significant advance in HPC technology.  The current HPC
This supplemental grant supports our investigation of ApoEr2?s interaction with the protein Reelin, and the effects of this interaction on synapse and dendritic spine formation (which are known to be important for learning and memory) in the br
ApoE and ApoE receptors in the molecular mechanisms of synapse formation
Supplement to NIH R03 award to advance progress on the analysis of human cytomegalovirus tegument proteins. This will be accomplished through the hiring of a new research assistant
REGULATION AND FUNCTION OF THE HCMV PP71 TEGUMENT PROTEIN
This supplement supported an undergraduate summer research student.  The project is ongoing, and involves back-crossing knockout mice into another genetic background. He performs genotyping and overall maintenance of the colony.  His work has p
DNA polymerase iota as a putative tumor suppressor
This grant provided a summer research experience for 2 undergraduate college students in health-related scientific research.
Hybrid Atomic Force-Optical Imaging System to Investigate Prenatal Nicotine
The P.I. proposes to study the role of auditory perception in mediating vocal learning in a songbird, the zebra finch. Young male zebra finches learn their songs from adult models through a process of imitation that resembles human speech acqui
Mechanisms Underlying the Development of Auditory Perception in Songbirds
The cochlear microcirculation is essential for normal hearing. A reduction of cochlear blood flow is involved in a number of hearing disorders. Pericytes, surrounding blood microvessels, play important roles for many organs in the regulation of
THE ROLE OF COCHLEAR PERICYTES IN CONTROL OF COCHLEAR MICROCIRCULATION
of the motor, and transient kinetic measurements to determine selected rate constants for the substrate binding to and product dissociation from the wild type and mutant myosin VIIA and actomyosin VIIA complexes. Thus the rate limiting step of
THE EFFECT OF DEAFNESS ASSOCIATED MUTUTATIONS ON MYOSIN VIIA FUNCTION
The basic functional of the auditory system is to allow listeners to detect signals in quiet as well as noisy environments. The ability to detect sounds in noisy environments is compromised in the elderly and the hearing impaired. The represent
This supplement is for 5R03HD055216-02, ?Mothers' attitudes about elective cesarean: results, expectations & satisfaction? (MADRES).  The original goals of the MADRES study were to study the attitudes and expectations of pregnant women with re
Mothers' attitudes about elective cesare
This RO3 addresses the fundamental question related to gonadotropin secretion from the anterior pituitary.  Specifically, why FSH is secreted constitutively and LH is primarily released through the regulated pathway.  This is an intriguing issu
EXPRESSION OF AN FSH ANALOG WITH A REROUTED SECRETION PATTERN IN TRANSGENIC MICE
Novel Intracellular Pattern Recognition Receptor Expression by Resident CNS Cells  While glial cells are recognized for their roles in maintaining neuronal function, there is growing appreciation of the ability of resident brain cells to initia
Novel Intracellular Pattern Recognition Receptor Expression by Resident CNS Cell
Fund two undergraduates and one high school student for summer resesarch.  These students will be working on the synthesis of novel glycodendrimer structures (undergraduates) and the generation of quantitative amounts of oligomeric sugars to be
Synthesis of Novel Water-Soluble Glycodendrimers as Anti-HIV Agents
This project investigates the potential of targeting two amino acid transporters, ASCT2 and LAT1, as therapy for human hepatocellular carcinoma (HCC), and to determine their role in HCC development and growth. The incidence of HCC is on the ris
Amino Acid Transporters ASCT2 and LAT1 in Human Hepatocellular Cancer Growth
This is an administrative supplement award to the existing parent R-15 grant (R15CA119253) that was awarded for a 1-year period.  The objective of this administrative supplement award is to purchase an equipment (intensified charge coupled de
Hand-held optical probe for fluorescence imaging of breast cancer
The purpose of this study is to elucidate the biochemical and molecular mechanisms by which the interaction of selenium (Se) and phytoestrogens reduces the risk for prostate cancer. The objective is highly significant; if successful, the study
Selenium, Isoflavones, Androgen Metabolism and Prostate Cancer Risk Reduction
Angiogenesis is required for the growth and metastasis of cancers.  One of the critical events that occurs during tumor formation, is the remodeling of the angiostatic vascular microenvironment to a pro-angiogenic microenvironment.  This remode
Mechanisms by which MAGP-2 Promotes Angiogenesis
Focus on manufacturing RNA-bound nanoparticles (RNPs). For this purpose gold, manganese or zinc-based core nanoparticles (NPs) will be prepared and RNA attached via delivery-enhancing materials (protamine or PAMAM dendrimer). Ultimately, as pro
Advances in obesity treatment may be provided by continued resolution of the neural circuits that mediate leptin, ghrelin, and insulin responses. Considerable recent research has detailed first and second order sites in hypothalamic regions tha
Role of Parabrachial Nucleus Neuropeptides in Feeding
Our aim is to compare the structure and function of different eukaryotic and archaeal Pus10 protein orthologs.  We will bioinformatically identify candidate residues and structures, which confer &#216;54 and &#216;55 activity in Pus10 using hom
Biochemistry & Molecular Biology 1245 Lincoln Dr
The molybdenum cofactor (Moco) is a remarkable metal center that lies at the catalytic heart of a variety of enzymes. The unique and `universal' Moco has the same core structure in all mononuclear molybdenum enzymes (MMEs) and is found in all f
MODELS FOR NITRATE REDUCTASES AND RELATED ENZYMES
Signaling Pathways and Microtubule Function
Research will be conducted to improve the performance and capability to resolve the widest possible variety of racemates of solid phase supported oligoproline chromatography columns.  One goal is to equal or surpass the capabilities of the best
Oligoproline chiral selectors and their applications
Development of Artificial Agonists for a Bacterial Riboswitch  The threat of bacterial infections due to lack of effective antibiotics has come to the forefront as these pathogens become resistant to almost every antibiotic available to the pub
Development of Artificial Agonists for a Bacterial Riboswitch
Epigenetic Biomarkers of Early Psychotropic Medication Exposure   The use of antipsychotics, antidepressants, and anti-epileptics in both pre-pubertal and post-pubertal windows of brain development raise concerns about the functional effects of
This application addresses Broad Challenge Area '(04): Clinical Research' and Specific Challenge Topic '04-MH-103: Interventions That Target Symptom Dimensions of Childhood-Onset Mental Disorders.' The family of cognitive-behavioral therapies (
Effect of D-Cycloserine on Treatment of PTSD in Youth
This application addresses broad challenge area (15) Translational Science and specific challenge topic 15-MH-101, Effects of Psychotropic Medications on Neurodevelopment and Behavior in Animal Models'. Antidepressants and anxiolytics are incre
USE OF A MOUSE MODEL OF ANXIOUS DEPRESSION TO ASSESS THE SAFETY OF PEDIATRIC ANTI
This proposal is called: A Vision of Hope: Integration of Palliative Care in Chronic Pediatric Disease. The project is directly responsive to the specific challenge topic, Methods to Enhance Palliative Care and End-of-Life Research. It is desig
A VISION OF HOPE: INTEGRATION OF PALLIATIVE CARE IN CHRONIC PEDIATRIC DISEASES
This application addresses broad Challenge Area (15): 15-NS-102: Translation of Gene Silencing Therapeutics. The proposed challenge set forth in the RFA is to extend the current understanding of the feasibility and safety of RNA interference (R
RNA Interference Therapy for Huntington's Disease: Studies in Non-Human Primates
This project is significant as it addresses scientific knowledge gaps in sophisticated quality of life and neurocognitive assessment tools, specifically the Neuro-QOL and the NIH Toolbox neurocognitive battery, through the use of a well-control
Validating New NIH Clinical Tools in Parkinson's Disease With and Without Depression - ARRA Stimulus Challenge Grant
Project Title: Analysis of Neural Circuits using a Genetically-encoded Silencer. Two postdoctoral students and one research technician will direct their effort to generate the constructs requited to generate these mice and to carry out analysis
ANALYSIS OF NEURAL CIRCUITS USING A GENETICALLY-ENCODED SILENCER
The Hastings Center (the nation's first and foremost bioethics research organization), NOVA (the nation's most-watched science program) and WGBH (PBS's leading producer of programming) have partnered to research whether a multi-platform media p
Designing Life: Stories from the Bioethical Frontier
Research and Treatment in Comparative Effectiveness, Quality Improvement (QI) and Investigational New Drugs (IND) Research examines the research-treatment interface in the context of traditional clinical trials, comparative effectiveness resear
RESEARCH AND TREATMENT IN COMPARATIVE EFFECTIVENESS, QI AND IND RESEARCH
Current experimental evidence supports a J- or U-shaped association between alcohol consumption and heart attack and/or high blood pressure. As such, while light-to-moderate drinking has been associated with protection from heart disease, heavy
NOVEL MITOCHONDRIAL MECHANISMS OF ETHANOL-INDUCED CARDIAC INJURY IN AGED FEMALES
Our goal is to determine the clinical, cognitive, imaging, genetic, and biochemical biomarker characteristics of the early (pre-dementia) stages of Alzheimer's disease (AD). The project builds on the NIA-funded AD Neuroimaging Initiative (ADNI1
Amyloid Imaging, VMCI, and Analysis for ADNI
The recent report that rapamycin increases the lifespan of mice is a major breakthrough in aging because it can be translated easily to humans. However, the critical question is whether long-term rapamycin treatment improves healthspan/quality-
CAN RAPAMYCIN RETARD AGE-RELATED DISEASES?
The major goal of this project is to assess the associations of genetic markers with cognitive decline among older African Americans and Africans so as to identify genetic factors that are related to this problem.
Genome-Wide Association Study of Cognitive Decline Among Older African Americans
illustrating the mitigating effects of CBLB502 on various elements of GI infrastructure damaged by radiation, (ii) define the target organs that contribute to the GI radiomitigation activity of CBLB502 with specific focus on bone marrow and li
Mechanisms of mitigation of radiation damage of GI tract by Protectan CBLB502.
Natural products and nature-derived materials continue to represent major analytical challenges in biomedical research. Their innate chemical complexity is of biogenetic origin, and can obscure correlations between chemical structures and obser
Spectrometric Validation of Botanical Materials and Reference Standards
This RC2 proposal is responsive to this Specific Topic because: 1) It focuses on an often lethal but rare disease: Merkel cell carcinoma (MCC), with prevalence of well under 200,000 cases in the US. 2) We will generate preliminary results that
Targeting MCPyV to overcome immune evasion in Merkel cell carcinoma
The class IA phosphatidylinositol 3 kinase (PI3K) signaling axis is perhaps the most frequently activated pathway in human cancer. In response to the activation of receptor tyrosine kinases (RTKs), G-protein coupled receptors (GPCRs) or Ras, cl
Targeting PTEN Null Tumors via Inhibition of the p110beta Isoform of P13 Kinase
Through a partnership between investigators in the Cancer Research Network (CRN) and Dana-Farber/Harvard Cancer Center, we propose to develop a resource with sufficient depth and breadth to support high quality cancer comparative effectiveness
Building CER Capicity: Aligning CRN, CMS, and State Resources to Map Center
Emerging imaging technologies are an important component of efforts to effectively detect and treat cancer. The American Recovery and Reinvestment Act of 2009 specifically targets the development of comparative effectiveness research (CER) to i
Comparative Effectiveness of Advanced Imaging in Cancer
1.	We purchased and received a mass spectrometer and have developed protocols for using it to sequence peptoids.  2.	We successfully created an on-bead 5-mer peptoid library with individual library members composed of all combinations of ten po
Novel Vaccine to Prevent HCV Infection and Hence Liver Cancer-ARRA Stimulus Grand Opps
Kaposi's sarcoma-associated herpesvirus (KSHV), or human herpesvirus 8, is the etiologic agent of Kaposi's sarcoma (KS), and other proliferative disorders. KS was one of two sentinel diseases that heralded the AIDS epidemic. Althought the level
KSHV proteins eliciting neutralizing antibodies and T cell responses
The central goal of this GO RC2 application is to leverage the collective resources of three institutions (VCU/Massey Cancer Center, MD Anderson Cancer Center, H. Lee Moffitt Cancer Center) and various associated support mechanisms (i.e., R01,
Proteasome/HDAC Inhibition in Leukemia/MDS; Phase I Trial and CorrelativeStudies
Cancer is a disorder of unrestrained cell proliferation, but increasingly it seems that not all proliferating cells in a tumor matter equally. As with cells in normal tissues, tumor cells appear to progress through lineage stages, in which the
Feedback, Lineages, and Cancer:  A Multidisciplinary Approach
HIV-caused AIDS is a potentially lethal disease with no vaccine or cure available at the moment. The obstacles to overcome when developing an effective HIV vaccine include devising a strategy that would generate cellular and humoral immunity wi
Project Title: A Six-Month, RCT of Probuphine Safety and Efficacy in Opioid Addiction.  We are conducting a  six-month, randomized, placebo and active-controlled, multicenter clinical trial of Probuphine in patients with opioid dependence for t
A SIX-MONTH, RCT OF PROBUPHINE SAFETY AND EFFICACY IN OPIOID ADDICTION
The long-term goal of this research project is to improve the efficacy of anti-nicotine vaccination/immunotherapy for smoking cessation. The proposal relates to the special interest of NIDA in RFAOD- 09-004: “Nicotine and Tobacco Research”
Improving the efficacy of anti-nicotine immunotherapy
Despite increasing recognition that BPA has harmful effects on the reproductive, nervous and immune systems. While higher urine BPA concentrations are associated with cardiovascular disease in humans, the effect(s) of BPA at environmentally rel
Defining the Impact of Dietary Bisphenol A on Heart Health in the C57BL/6 Mouse
Rapid advances in nanotechnology will be accompanied by the exposure of millions of individuals to products containing nanomaterials. Carbon Nanotubes (CNTs) are engineered nanomaterials designed for multiple uses (electronics, engineering, med
Lung Toxicity of Carbon Nanotubes in Models of Pre-Existing Respiratory Disease
Obesity and its complications are a major health concern in the US and other industrialized nations. Based on the coincident increase in industrial chemical production and the meteoric rise in body weight in recent decades, a mechanistic connec
Defining the role of BPA in promoting obesity & associated metabolic complication
This grant is responsive to recent data suggesting that bisphenol A (BPA) may contribute to asthma, possibly through heightened inflammation and T regulatory cell dysfunction. Preliminary data show a dose-dependent association between early-lif
Early-life Bisphenol A, Immune Dysregulation, and Inner-city Pediatric Asthma
While it is now recognized that the manufacture of nanomaterials may present unique risks to humans and the environment, the field of nanotoxicology remains at an early stage. Nanomaterials, the building blocks of nanotechnology, constitute a v
Integrated Nanoparticle Characterization and Toxicity Assessment
An important potential enabling resource for Personalized Medicine is the combination of a DNA repository with Electronic Medical Record (EMR) systems sufficiently robust to provide excellence in clinical care and to serve as resources for anal
VESPA:  Vanderbilt Electronic Systems for Pharmacogenomic Assessment
Mammalian development is driven by the successive restriction of developmental potential as the totipotent zygote generates the diversity of mature cell types present within an adult animal. The characteristics adopted by each cell within the a
EPIGENETIC DYNAMICS OF DEVELOPING GERM CELLS AND EARLY EMBRYOS
Title: CNV Atlas of Human Development Abstract: The recent discovery that copy number variations (CNVs), the loss or gain of small genomic segments, is common in all normal individuals and plays a major role in human phenotypic variation and di
Population-based biobanks are a critical resource for identifying disease mechanisms and developing screening tests for biomarkers associated with certain disorders.  The California Department of Public Health has been banking newborn specimens
Development of a Research-Ready Pregnancy and Newborn Biobank in California
DESCRIPTION (provided by applicant):  DNA sequencing is currently in the midst of disruptive technological shifts, with 454, Illumina, and Solid providing us with enormous throughput increases and large reductions in cost per base. Massively pa
A Universal Front End to Improve Assembly Outcomes for Next-Gen Sequencing andRe-Sequencing
In this program, we will enable direct DNA methylation profiling during real-time DNA sequencing, without bisulfite conversion. We will accomplish this by tailoring Pacific Biosciences? high throughput Single-Molecule Real-Time (SMRT) DNA seque
Direct Single Base-Pair Real-Time DNA Methylation Sequencing
Personalized medicine will depend on molecular signatures to match the right patients to the right drugs, first in clinical trials, then in clinical practice. Personalized medicine is a new paradigm in which information technology, science, and
This stage one TRIP application will enable a phase II clinical trial of a new therapy to treat sickle cell disease (SCD) in two years. The basis of our proposal is our recent discovery that invariant NKT (iNKT) cells contribute importantly to
CTRIP: Treatment of Sickle Cell Crisis with inhibitors of NKT cell activation
Hutchinson-Gilford Progeria Syndrome (HGPS or progeria) is a rare autosomal dominant 'premature aging' disease. Children die at a median age of 13 years due to heart attacks and strokes caused by accelerated, global arteriosclerosis. The HGPS m
Phase II Trial of Lonafarnib, Pravastatin and Zoledronic Acid in Progeria
Patient recruitment and retention Patient recruitment and retention of study subjects has been excellent in this study.  The COMET Network was able to screen 108 potential subjects.  From these there were 12 screen fails, 3 subjects withdrew co
CTRIP: MOLECULAR PHENOTYPES OF RAPIDLY PROGRESSIVE IDIOPATHIC PULMONARY FIBROSIS
Comparative phenotypic, functional, and molecular analysis of pluripotent stem cells arguably the most significant challenge in stem cell biology today is determining whether human induced pluripotent stem cells (hiPSC) are truly equivalent to
Comparative phenotypic, functional, and molecular analysis of ESC and iPSC
We are embarking on contributing to a large catalogue of DNA sequence variation in phenotyped samples and to pioneering the application of this depth and scale of data to the analysis of key cardiovascular phenotypes. We propose to do this by (
Comprehensive Sequencing and Analysis of Variation in NHLBI Cohorts
Twin studies have provided insights into multiple disease and developmental endpoints. Because their genetic and environmental similarities are easily understood, twins can elucidate the contributions of genetic and environmental factors to ill
Building a Unique Resource: A National, Community-based Twin Repository
American Indians and Alaska Natives (AI/ANs) are at increased risk for Type 2 diabetes when compared to other Americans, a gap that continues to widen. Cardiovascular disease (CVD) has become the number one cause of death among AI/ANs, is now m
Addressing Diabetes/CVD Health Disparities among American Indians: A Transdiscipl
Chronic illness and health disparities are prevalent in the United States. More than 61 million Americans have heart disease, 20 million have diabetes, 50 million have hypertension, and 7.4 million have kidney disease. Those from racial and eth
Electronic Self-Management Resource Training to Reduce Health Disparities
Convincing evidence of the importance of the social determinants of health and health inequity continues to be documented. Relatively few students and even fewer health practitioners, however, receive training in taking action. Healthy People 2
Design and Implementation of A Health Equity Educational And Social Networking We
The purpose of the project is to develop and test new performance measures in community care coordination using the Pathways Model as the framework for developing the measures.  There are four major goals for this project, which are to: (1) ref
Standardizing Community Care Coordination Measures Linked to Improvement in Qual
Major depressive disorder (MDD) is the leading cause of disability in the world (WHO). The severe, recurrent form often onsets during childhood or adolescence and becomes chronic. Heritability (35-70%) is similar to that of other common disorde
Depression susceptibility genes and networks: expression, eQTL and GWASanalysis
Common and Rare Genetic Factors in an Ethnically Homogeneous Schizophrenia Cohort:  This project aims to perform a genomewide association study (GWAS), as well as extensive next-generation resequencing, in a large cohort of Ashkenazi Jewish pat
Common and Rare Genetic Factors in an Ethnically Homogeneous Schizophrenia Cohort
Advances in genomics are revolutionizing medicine with novel discoveries that help understand mechanisms and design novel treatments. For mental illnesses to join genomics we need robust phenotypic developmental data linked to brain function. T
Neurodevelopmental Genomics: Trajectories of Complex Phenotypes
Advancing new therapeutic targets into innovative drugs is a major translational bottleneck in the southwestern United States.  To address this urgent need, we aim to build a critical resource closing major medicinal chemistry resource gaps for
The Southwest Comprehensive Center for Drug Discovery and Development
Proteomics remains virtually without context.  The project will show context-specific proteomic maps of wild type neurons in the intact brain, furnishing a much-needed intellectual infrastructure to transform definitions of the molecular circui
IN SITU PROTEIN-PROTEIN INTERACTION NETWORKS (PIN) OF NEURONS.
DESCRIPTION (provided by applicant): Evaluation of research effort, such as estimation of the proportion of treatment successes in clinical trials, has important ethical, scientific, and public policy implications. Researchers, policymakers, fu
Treatment Success and Ethical Principle of Equipoise
Histone deacetylases (HDACs) are enzymes that regulate the functions of histone proteins by catalyzing the removal of acetyl groups from lysine residues. They play a pivotal role in the regulation of gene transcription and are indispensable in
Regulation of non-histone protein functions by hostone deacetylases
Onchocerciasis is a debilitating disease caused by infection with the parasite Onchocerca volvulus. The public health importance of onchocerciasis has been recognized by the international community, which has sponsored several programs whose go
Collaborative Research: Spatial Modeling of Onchocerciasis Foci in Africa by Remote Sensing
Colorectal cancer is a preventable yet highly prevalent disease worldwide. Poor patient compliance with screening procedures increases the mortality due to colorectal cancer. There is an urgent need for chemopreventive measures for this tumor t
This award will provide partial support for the acquisition of a Biacore T100 surface plasmon resonance system at the University of Texas Medical Branch (UTMB) in Galveston. Molecular recognition is one of the most important problems in biology
A STATE-OF-THE-ART BIACORE T100 FOR UTMB
This application covers the acquisition of a quadrupole time-of-flight (Q-TOF) ion mobility hybrid mass spectrometer. This instrument will be added to an existing core facility in the University of Georgia, College of Pharmacy and be directly i
Q-TOF Ion Mobility Mass Spectrometer for Drug Discovery
College of Pharmacy, Room 153 RC Wilson Building
This award was for the purchase of a Illumina GAIIx high-throughput sequencer. (HTS)
This is an instrumentation grant. Every cell and tissue biology research program has needs for microscopic visualization of research specimens. While some of these needs are best addressed by traditional, routine light and confocal microscopy o
Ultrasound offers unique capabilities for investigating tumor development in terms of anatomy and perfusion. The new instrument will accelerate development of new therapies in our institution, which will be directly translatable to the clinic,
Small Animal Ultrasound System - ARRA Stimulus Equipment Funds
This project, funded under the American Recovery and Reinvestment Act of 2009 (Recovery Act), promotes diversity among health professions students and practitioners by providing scholarships for students from disadvantaged backgrounds. Eligible
The purpose of the program is to provide scholarships to full-time students who demonstrate strong financial need and who are majoring in the Pharmacy or Physician assistant disciplines. we are identifying students who demonstrate need as based
The university follows the guidelines that has been provided by HRSA to identify all students that qualify based on racial/ethnicity
ARRA - Scholarship for Disadvantaged Students
Scholarships for Disadvantaged Students in Allopathic Medicine
The long term goal of our program is to develop novel broad spectrum chemotherapeutics that can be used for Phase 1 clinical trials for treating the diseases caused by priority pathogens such as Francisella tularensis, Burkholderia pseudomallei
Development and Formulation of Broad Spectrum Antimicrobials for Biodefense
Orthopoxviruses (Smallpox, Monkeypox, etc.) have the potential for causing serious human health problems.  Although Smallpox has been eradicated from the wild, it is feared that there may be rogue stockpiles that have the potential to be used a
Development of a Therapy for Smallpox, Vaccinia, and Monkeypox
Influenza virus infections cause significant morbidity and mortality in the US and the world. Cytolytic CD8 T lymphocytes are critical for the control of respiratory viral infections, and their recruitment into tissues is essential for local im
Regulation of T lymphocyte immunology to influenza virus
The proposed work will establish national networking of scientists by providing a new software system (VIVO) and support for scientists using VIVO.  Scientists using VIVO will be able to find other scientists and their work.  Conversely, scient
VIVO: Enabling National Networking of Scientists
This proposed Patient-Reported Outcomes Measurement Information System (PROMIS) Statistical Center (PSC) will advise and educate members of the network on a range of qualitative research methods; develop and implement processes to ensure data q
Pt Reported Outcomes Measurement Information System Statistical Center(U54)
The Department of Health has received a grant award from HRSA for the expansion of the National Health Services Corps in Vermont. These funds will be used to support a subgrant to the Bi-State Primary Care Association to carry out recruitment a
Title: MODELING HIV- 1 SIRNA THERAPY  The overall hypothesis to be tested in this proposal is that RNA interference can be developed as a therapeutic modality for HIV-1 disease. RNA interference is a highly evolutionary conserved cellular mecha
This project will characterize the role of the ubiquitin ligase RNF5 in ER stress response in breast cancer and melanoma tumors, where its expression is elevated. Our preliminary results established a novel link between RNF5, ER stress and key
Characterization of RNF5 - A Novel RING Finger Protein
The research investigates a mutation that affects the number and placement of glutamate receptors at the synapse.  Chemical transmission in the central nervous system (CNS) relies on effective communication between neurons.  This process is de
Investigating the Role of Atgl in the Regulation of Glutamate Receptors.
NIH Announces the Availability of Recovery Act Funds for Competitive Revision Applications. This competing revision supports a significant expansion of the scope of the parent R01 Ag16613. The parent R01 investigates regulation and targeting of
AKAP Regulation of PKA Targeting in the Heart
measures and therefore not subject to recall biases, and a new diary-based approach to measuring quality of life, the Day Reconstruction Method (DRM). We intend to begin to test the usefulness and validity of these measures among lower extremi
MEASURING HEALTH-RELATED QUALITY OF LIFE IN OLDER ADULTS WITH CHRONIC ILLNESS
This Competitive Revision application is in response to NOT-OD-09-058 'NIH Announces the Availability of Recovery Act Funds for Competitive Revision Applications.' We request competitive supplement to our NIH grant R21AG032567 entitled 'Role of
Role of p62 in Protein Aggregation and Neurodegeneration in ALS
Alzheimer?s disease (AD) is characterized by a dominant component of inflammation, which in concert with enhanced amyloid production leads to secondary neuronal degeneration. Additionally, recent evidence also suggests a strong link between cer
Validation of the PGE2 EP4 Receptor as a Therapeutic Target in AD
In our knowledge of the mechanism of sexual transmission of HIV-1 there is a very important gap. The population of HIV viruses soon after infection is, in most cases, monotypic; it is as if a single virus initiated infection. The population of
HIV-1 subtype B transmission in a heterosexual incident
Herpesvirus-encoded protein kinases (HPKs) have attracted increasing attention lately due to the growing evidence of their involvement in different aspects of the viral life cycle, making them appealing targets for antiviral therapy. The broad
Definition of Srtuctural Organization and Enzymology of the EBV Protein Kinase
This administrative supplement is requested to provide salary and supplies for a talented post-doctoral student who will extend the analysis of human IL13 polymorphisms by generating and analyzing additional TG lines representing the Th2 locus-
Mouse Models for the Functional Analysis of Asthma-Associated Human Polymorphisms
is to provide hands-on experience with laboratory research, encouraging the student's pursuit of graduate school. We also hoped this bright student might develop laboratory expertise quickly enough to generate data that would aid in our labora
On the parent R21 award, we have established a system of passively transferring protective anti- influenza nucleoprotein monoclonal antibodies into both B lymphocyte-deficient mice as well as normal mice. This is a significant step in allowing
MECHANISMS OF NON-NEUTRALIZING ANTIBODY-MEDIATED PROTECTION FROM INFLUENZA VIRUS
This competitive revision of R21 AT004234-01 'Effectiveness of Integral Yoga on Objective and Subjective Menopausal Hot Flashes' is in response to NOT-OD-09-058: NIH Announces the Availability of Recovery Act Funds for Competitive Revision Appl
Effectiveness of Integral Yoga on Objective and Subjective Menopausal Hot Flashes
Parent R21 Grant: Surrogate and Sentinal Technologies to Monitor Stability of Cancer Phosphoproteins                                                                                                                    The purpose of this ARRA sup
Surrogate and Sentinal Technologies to Monitor Stability of Cancer Phosphoprotein
ARRA award funds will  carry out a pilot study where we will examine MCJ expression in tumor tissues of breast cancer patients. Since no previous published studies have examined MCJ in breast tumors the purpose of this Revision application is t
MCJ function in mouse mammary tumor properties
This application is submitted in response to NIH Notice Number NOT-OD-09-058 entitled 'NIH Announces the Availability of Recovery Act Funds for Competitive Revision Applications'. Current techniques for full karyotype analysis rely on metaphase
Accelerating Cancer Research with Single Cell Arrays
Characterization and Use of Fluorescent Endocannabiniod Transporter Substrates.
The goal of this research proposal is to understand the nature of the interactions between sweet proteins and sweet taste receptor (STR). Recent chimera and mutagenesis studies show that both the Venus Flytrap Module (VFTM) and Cysteine Rich Do
We are conducting an experiment to examine how adults learn a grammar involving combining sounds of an artificial language.  Grammar learning provides an advantage for investigating the interaction between genes and language acquisition because
DESCRIPTION (provided by applicant): Positional cloning has helped identify the molecular causes of many of Mendelian disorders. Genes involved in the more common forms of deafness and ataxia have been identified and are often clinically tested
Comprehensive genomic approach to rare hearing disorders and ataxia
Selection of odorant receptor (OR) and maintainence its expression in the olfactory sensory neuron (OSN) is not well understood.  To investigate the mechanism of OR selection and maintenance, in the parent application we proposed to define OR s
Subproject for Institution # 08-003807: Regulation of Odorant Receptor Gene Expression in Olfactory Sensory Neurons
. Candida albicans causes both mucosal and disseminated disease. Oropharyngeal candidiasis (OPC) results in significant morbidity in many patients, especially those with HIV/AIDS. Hematogenously disseminated candidiasis (HDC) is a healthcare-as
GENETICS OF SUSCEPTIBILITY TO CANDIDIASIS
Project Summary The association between the physical environment and the risk of being overweight or obese are difficult to estimate because residents are not randomly distributed by neighborhood. When neighborhood selection bias exists, estima
NEIGHBORHOOD CHARACTERISTICS & BODY MASS INDEX: SELECTION OR CAUSATION?
1. The holographic recording material proposed on the parent grant proves to be too insensitive for practical application. We plan to explore a range of other holographic materials including near infrared (NIR) sensitive materials (InPhase Tech
INITIAL BIOMEDICAL STUDY OF TURBIDITY SUPPRESSION BY OPTICAL PHASE CONJUGATION
The significant contribution of the Administrative Supplement would be to provide for the long-term hiring of a Research Assistant at UAB which will allow us to increase the rate at which we record using fMRI and electrophysiology in this study
STEREOSCOPIC MOTION-IN DEPTH PERCEPTION FMRI AND NEUROPHYSIOLOGICAL STUDIES
Sexual dysfunction, including disorders of sexual desire, arousal, orgasm and sexual pain, affects approximately 40% of American women, often with significant consequences on quality of life. Despite the prevalence, the causes of female sexual
The broad, long-term objective of this study is to validate Measurement of Youth Media Exposure (MYME), a multimethod instrument designed to obtain a more sensitive and comprehensive assessment of adolescent use of and exposure to entertainment
Measurement of Yourth Media Exposure and Health Outcomes
DESCRIPTION (provided by the applicant) In women, one function most adversely affected by the age-related decrease in ovary reserve is decreased fecundity. The basis for this age-related change is the failure of dominant follicles to release eg
A NOVEL FUNCTION OF THE OOCYTE IN ESTROGEN-REGULATED FSH ACTION
The broad, long term objective of the parent proposal, Sequence Acquisition from Mapped Single DNA Molecules, is to develop a scheme for acquisition of sequence information using large genomic DNA molecules. Sequence information is revealed by
ARRA Sequence Acquisition from Mapped Single DNA Molecules
In vascular diseases, contractile genes are often downregulated in smooth muscle cells (SMC). A crucial regulator of their expression is a complex involving coactivators of the Myocardin family recruited to a conserved DNA sequence, the ‘CArG
Role of BMP Signaling in Vascular Wall Homeostasis
DESCRIPTION (provided by applicant): Cardiomyopathy and heart failure are potentially fatal complications of diabetes, but the molecular mechanisms leading to diabetes-induced cardiomyocyte damage are not well understood and therapies targeting
TXNIP: A Novel approach to prevent diabetic cardiomyopathy and heart failure
Myocardial infarction is a major cause of morbidity and mortality in the United States and most developed countries. Heart transplantation is an effective therapeutic modality in reconstituting the function of damaged heart. However, widespread
ARRA: Scalable bioprocess for cardiomyocyte generation from human embryonic stem cells
Gene therapy has long been touted to hold the promise of cure for a variety of congenital diseases. However, gene therapy trials are still small in number and scale due to several problems that have prevented wider application of current techno
Testing the safety and efficacy of inhibitory RNA mediated purine analog resistan
This administrative supplement would accelerate work on the two aims of the parent R21 grant:  1) Develop, evaluate, and make freely available an end-user natural language processing (NLP) development tool suite to facilitate rapid and effectiv
Investigating the generalizability of natural language processing of EMR data
The study's aim is to develop a bedside assay to detect pulmonary micro-aspirations of gastric contents. Such a test is needed to differentiate between frequent and infrequent aspirators so that interventions can be planned accordingly. A total
Development of a 'Nurse-Friendly' Bedside Rest for Aspiration
Title: Regulation of Synapse Specificity in the Developing CNS. This award supports undergraduate research in the laboratory by providing them with paid employment during the summer and fall. Three undergraduate students will work on this proje
The aim of the current project is to utilize empirical electrophysiological data (magnetoencephalography; MEG and functional magnetic resonance imaging; FMRI) to inform a human model of the putative pathology underlying cognitive deficits and s
Attentional Dysfunction and Recovery in Traumatic Brain Injury (TBI)
This award is to support Summer Research Experiences for Students and Science Educators. It will focus on further characterizing the expression pattern of IFN- and TNF, by RT-PCR and qPCR. In parallel, we will also generate constructs to expres
A XENOPUS LAEVIS RESEARCH RESOURCE FOR IMMUNOBIOLOGY
Herpesvirus latency and reactivation in macaque models of human disease  --  The goal of the parent grant is to characterize the life cycle and biology of the two distinct lineages of macaque rhadinoviruses related to human herpesvirus 8 that a
Herpesvirus latency and reactivation in macaque models of human disease
This project provides short-term experience and training in biomedical research for undergraduate students from underrepresented and disadvantaged groups. The Principal Investigator, Judith S. Bond, PhD, is an NIDDK funded investigator for more
PREPARING FOR RESEARCH CAREERS RELATED TO DIABETES, DIGESTIVE & KIDNEY DISEASES (ADMIN SUPP)
This proposed STEER program is intended to support the annual participation of eight academically talented undergraduates in the Environmental Health Sciences Summer Undergraduate Research Program (EHS-SURP). The overall goal of EHS-SURP is to
EHS SUMMER UNDERGRADUATE RESEARCH PROGRAM (EHS-SURP)
The goal of the MBRS RISE Program is to increase the number of young people who will enter biomedical fields.  This supplement proposal will provide opportunities to implement a plan to strengthen and support the CAU RISE students while also pr
Enhancement of Student Training in Biomedical Sciences
The Post-Baccalaureate Research Education Program (PREP) at the University of California Irvine (UCI) aims to increase the pool of admitted underrepresented minority graduate students by encouraging, orienting and better preparing recent baccal
Post-Baccalaureate Research Education Program (PREP)
This program is designed to provide interim positions for under-represented minority students and students from disadvantaged groups with post- baccalaureate degrees interested in pursuing graduate education. The focus is on research training u
Post Baccalaureate Research Education Program (PREP)
The supplement is to enhance the University of Minnesota Duluth 'Pathway to Advanced Degrees in Life Sciences Program.'  The program supplement will increase participation by underrepresented minorities in biomedical research. Program activitie
Pathway to Advanced Degrees in Life Sciences
This administrative supplement focuses on the design and implementation of a comprehensive evaluation of the mobile laboratory program created by BUSM and replicated in substantially equivalent forms at SEPA and non-SEPA funded sites throughout
CityLab: A Systems Approach to Biology- Phases I/II
DESCRIPTION (provided by applicant): The overriding goal of this Phase II project is to promote national dissemination of the Phase I HealthRICH products and resources, as these materials effectively encourage young teens and their families to
HEALTHRICH: HEALTH RISKS, INFORMATION AND CHOICES. PHASE II
This award is a supplement to a NIH-NCRR Science Education Partnership Award (SEPA) grant, which is designed to teach high school students about clinical research.  As part of the parent grant, a partnership was formed between the University of
EDUCATING HIGH SCHOOL STUDENTS AND THEIR FAMILIES ABOUT CLINICAL RESEARCH (PHASE
There is a serious gap nationwide in the number of individuals whose training emphasizes global health issues. The number of professionals with firsthand experience in global health issues is critically low. The overall objective of the Case Fr
Integrated Programs & Curricula for Global Health Education
Macrophages are central to our innate immune responses to infection and malignancy. Bacterialproducts, such as Gram negative lipopolysaccharide (LPS), and cytokines, such as interferons (IFNs),program the expression of an array of pro- and anti
Differentiative Signals for Macrophage Activation
We seek to establish mechanisms for quite general processes, such as membrane fusion and perforation, as well as to lay the groundwork for discovering novel classes of antiviral therapeutics and for designing new vaccines.
Molecular Genetic Analysis of Colorectal Cancer: Activation due to phospho-peptide binding To fully elucidate the activation mechanism of the oncogenic mutations of PI3K? we designed mutants at the interfaces of the SH2 domains (both nSH2 and c
MOLECULAR GENETIC ANALYSIS OF COLORECTAL CANCER
Cigarette smoking causes 30% of all cancer mortality in the developed world. Tobacco-specific nitrosamines, the subject of this proposal, are accepted causes of cancer in people who use tobacco products. The two most carcinogenic of these compo
METABOLISM OF CARCINOGENIC TOBACCO-SPECIFIC NITROSAMINES
cellular iron. This in turn reduces susceptibility to subsequent             stress. In this proposal we explore the hypothesis that ferritin regulation is       instrumental in modulating the magnitude and character of the cellular response
Ferritin, Iron Homeostasis and Cellular Stress
Accumulation and switches of laminin isoforms is a feature of glomerulonephropathy ) and aging kidney.  In the current R37 funding we developed powerful strategies to study transcriptional expression of laminin genes in their native genomic env
Laminin Gene Expression in Glomerular Cells
The large?conductance Ca2+?sensitive potassium (BK) channel plays an important role in urinary bladder (UB) function, as evidenced by the fact that targeted disruption of the BK pore?forming ??subunit results in detrusor overactivity and urinar
Ca2+ Sparks and Urinary Bladder Smooth Muscle Excitability
ARRA - Mechanisms of Mitotic Spindle Assembly and Function: Supplement  Our goal is to discover how protein interactions between kinetochores and spindle microtubules function to achieve accurate chromosome segregation in mitosis and meiosis. O
ARRA - Mechanisms of Mitotic Spindle Assembly and Function: Supplement
This award is issued in response to Notice OD-09-060, Recovery Act Administrative Supplement brings together three scientist from two institutions to develop new bianalytical tools and methods to understand the molecular changes that signal par
Metalloregulation by MerR and Fur Protein Families
Dosage compensation is a striking example of the interplay between gene-specific regulation and chromosomal architecture. This process has evolved to make X-linked gene expression equivalent in males with one X chromosome and females with two.
Molecular Genetics of Dosage Compensation in Drosophila
Resolution of the genetic and environmental components of a disease trait is an important step in developing methods for prevention and treatment.Identification of genes through family-based designs has increased understanding of the biology un
METHODS FOR THE GENETIC EPIDEMIOLOGY OF COMPLEX TRAITS
Department of Statistics, Padelford Hall
A protein complex named Saga, is located in every cell of the human body.  It is a major regulator of gene transcription and is implicated in the development of several forms of cancers and neurodegenerative diseases. To understand the role of
Mechanisms of Transcriptional Regulation in Chromatin
As described in the parent proposal, RNA dynamics and conformational transitions are unbiquitous in RNAmediated cellular events and processes such as pre-mRNA splicing, translation, and RNA catalysis/self-splicing. Within this context, P1 duple
This award will purchase microscope image acquisition and processing equipment that is essential for the studies that use fluorescence image analysis to study bacterial cell cycle events and the structure and function of the bacterial cytoskele
THE DEVELOPMENT OF SUSTAINED ATTENTION IN INFANTS The objectives are to study the development of sustained attention in young infants and to relate development in sustained attention to concurrent heart rate (HR) changes and brain activity (EEG
THE DEVELOPMENT OF SUSTAINED ATTENTION IN INFANTS
' This application is a request for an administrative supplement from the American Recovery and Reinvestment Act of 2009 (announcement NOT-OD-09-056) for our parent grant, HD33438, “Analysis of Reproductive Function Using Transgenic Mice”.
ANALYSIS OF REPRODUCTIVE FUNCTION USING TRANSGENIC MICE - PARENT GRANT R37HD33738
The overall goal of this work is to understand how the motor cortex constructs movement plans and implements them as actions. Previous work in this project demonstrated that neural population activity in the macaque monkey primary motor cortex
Our work addresses the functions and mechanisms of long-range growth factor signaling in vivo and in vitro. The title of our work is: The control of synapse assembly by target-derived Nerve Growth Factor (NGF). The overall purpose of this proje
NEUROTROPHIN SIGNALING AND REGULATION OF GENE EXPRESSION
The long term goal of this project is to develop new technology that will allow rapid user- defined patterning of proteins on cell culture substrates at dimensions ranging from 50 nanometers to millimeters. Patterned cell culture substrates are
Nanometer-scale protein patterns for cell culture by laser inactivation
Transmission electron microscope (TEM) tomography provides three-dimensional images at the nanometer scale. It is a mainstream technique in biological electron microscopy, and is rapidly finding applications in the semiconductor and nanotechnol
Supplement for System for generation of frozen-hydrated samples using the Focused Ion Beam Microscope.
The purpose of the AARA funding is to enhance the randomized evaluation of a Internet  program to train Nursing Assistants (NAs) in long term care facilities  (LTCs).  Participants will learn to  prevent aggressive behaviors by residents, or
Staff Training to Manage Aggressive Resident Behaviors
Project Title: 'Optoacoustic imaging enhanced by gold nanorods' Supplemental funding will accelerate the development and market potential for a laser optoacoustic imaging system with enhanced sensitivity and resolution that uses a novel optoaco
Optoacoustic imaging enhanced by gold nanorods
Title: Visual Programming Tool for Integrated Gene/Protein Networks in Cancer Research. Under the parent award, the team is developing a software tool that will allow multidisciplinary teams of researchers to meaningfully integrate knowledge ab
Visual Programming Tool for Integrated Gene/Protein Networks in Cancer Research
Development of Oncomine Professional as a Platform for Biopharmaceutical Research (Supplement): DNA microarray studies, largely sponsored by the NIH and other granting agencies, have generated a wealth of data uncovering the complex gene expres
Development of Oncomine Professional as a Platform for Biopharmaceutical Research (Supplement)
The aim of this research is to develop an improved, synthetic bone graft material for use in dentistry. The loss of teeth is often accompanied by the loss of jaw bone. Restoring this lost bone is often a prerequisite for the installation of den
Calcium Sulfate Based Bioactive Bone Graft
For this research project we developed a new method for concentrating submicrometer and ultrafine airborne particles, which has application to characterization for environmental health studies. The project used PhD and BS scientists and enginee
A Miniature Monitor for Time-Resolved Airborne Particle Chemistry
DESCRIPTION (provided by applicant): The current state of the art of in silico drug discovery relies almost exclusively on molecular mechanics force fields, such as AMBER, and empirical potentials. It is well known that while these approaches a
Deploymentment of Quantum Mechanical Pairwise Energy Decomposition for Drug Discovery
Human cytomegalovirus (HCMV) infection has serious consequences for immunocompromised individuals, such as AIDS and organ transplant patients and congenitally infected newborns. Of symptomatic newborns, 12% die and many of the survivors suffer
Early interactions of DNA viruses and host
To obtain a detailed understanding of both innate and adaptive immune responses to bacterial pathogens that cause repeated respiratory tract infections in chronic obstructive pulmonary disease (COPD) patients. We are studying how key outer memb
Innate and adaptive immune response to bacterial infections in COPD infections
Respiratory synctial virus (RSV) is a major cause of often serious, life-threatening lung disease in infants and young children, immunosuppressed organ transplant recipients, patients suffering from cystic fibrosis, congenital heart disease, an
(ARRA) Antiviral activity of leflunomide against respiratory suncytial virus
Abstract An exciting development in the innate immunity field is the discovery that macrophages enlist autophagy to protect their cytoplasm from infection. Nutrient deprivation has long been known to induce autophagy, but how infection rapidly
Autophagy as a component of the innate immune response
In the parent grant, we proposed to 1) Determine the ability of human PTH (hPTH) to mitigate or prevent radiation-induced thrombocytopenia in response to a radiation dose resulting in 30% lethality by 30 days (LD30/30) or 95% lethality by 30 da
Parathyrad Hormone in Prevention and Mitigation of Thrombocytopenia
As specified in our application, the purpose of the administrative supplement is:  1. Keep our GI radioprotection team together as we continue to submit related proposals, pursue other funding opportunities, and mentor new students. a. Provide
Protection against radiation-induced damage to intestinal nutrient transport
With the scientific progression, we found that the radiation-induced alteration of electrolyte transportation could be reversed towards normal as evidenced by the Ussing Chamber assay. The supplemental money allowed us to facilitate this part o
A NOVEL MITIGATION AGENT FOR GASTROINTESTINAL SYNDROME OF ACUTE RADIATION INJURY
Stroke induces infiltration of peripheral immune cells into infarct territory and thus exposes blood/serum components to the brain. Because CD36, an inflammatory mediator that contributes to stroke-induced injury, is expressed in peripheral org
The role of CD36 in ischemic inflammation and injury
The overall purpose of our project funded by the Recovery Act is to structurally and functionally analyze the small nuclear RNA (snRNA) variants in humans.  Our supplemental proposal aims to examine the assembly into splicesomes and the splicin
Tissue Specific and Developmental Expression of snRNA Variants in the Silk Moth
The capability to regenerate lost or damaged organs is severely limited in humans and most vertebrate animals. Other animals, in contrast, have remarkable regenerating abilities. Among these are the echinoderms, a group of animals closely relat
Molecular Control of Intestinal Regeneration
This project will provide critical information on the mechanisms leading to different forms of epilepsy, a devastating and very common neurological disorder. This project seeks to tackle problems related to the neurotransmitter release machiner
Molecular Determinants of Mossy Fiber Presynaptic Channelopathies in Epilepsy
Pif1P's Regulation and Role in Telomere End Protection in S. cerevisiae
Pif1p's Regulation and Role in Telomere end Protection in S. cerevisiae
which was funded by NIGMS and NIDDK. The primary aims of the proposed supplement are to increase the number of hours of the current part-time registered nurse and research technician and to procure an ultrasound machine to add a measure of the
Characteristics of Metabolically Obese but Normal-Weight Hispanic Women
The long-term objective of this project is to develop an environmentally friendly method for the preparation of 2-deoxy-C-aryl glycosides, a family of natural products which demonstrate important biological properties such as antitumor, antibio
AN ENVIRONMENTALLY BENIGN METHOD FOR THE SYNTHESIS OF C-ARYL GLYCOSIDES
Individual investigator-initiated research projects for faculty at MSIs to conduct research of limited scope in environments with limited research infrastructure/facilities.
A Periplasmic Global Regulator, ExoR, for Bacterial Invasion of Host Cells
Project Title:  Identification of Transamidated Protein Involved in Cell Death Induction.  Aim #1: Induction of protein transamidation by using the unique active TG that has never been used in cellular transfection.  Aim #2: Identification of t
Identification of Transamidated Protein Involved in Cell Death Induction
The goal of this training grant continues to be the training of pre and post-doctoral students in the discipline of cancer biology research so that they can participate in finding solutions to the problems associated with human cancer. The appr
Predoctoral Training in Pharmacological Sciences  This predoctoral training program is dedicated to training outstanding scientists in the pharmacological sciences. A highly productive and well-funded faculty provide a broad diversity of resear
This competitive grant renewal requests a continuation of support for years 26-30 for some of the predoctoral students in the Brown University Graduate Program in Molecular Biology, Cell Biology and Biochemistry (MCB). Students are admitted to
TRAINING IN MOLECULAR AND CELL BIOLOGY AND BIOCHEMISTRY
Multidisciplinary research at the Chemistry:Biology interface has expanded so rapidly in the past few decades that such cross-training is now crucial for the development of the next generation of chemists and biologists. The objectives of the p
TRAINING AT THE CHEMISTRY: BIOLOGY INTERFACE
The goal of the Medical Scientist Training Program (MSTP) is to train students in clinical medicine as biomedical research scientists.  Training is offered in a diverse number of medically related scientific areas.  This is accomplished by  mea
We seek one additional training slot for the Biotechnology Training Program (BTP) at UVa.  In the first nine (9) years of funding, we built the BTP into a highly interactive community of Ph.D. trainees drawn selectively from an annual spring co
One student has been appointed to the training grant due to ARRA funds.  A second student will be appointed effective July 1, 2010.  This will complete the training funded by ARRA.
Cellular and molecular foundations of biomedical science
The goal of this training program is to train biostatisticians to take a leadership role in developing new interdisciplinary scientific research. This will be achieved by providing rigorous training in the disciplines of statistics and microbio
Statisics in Microbiology, Infectious Diseases and Bioinformatics
The first goal is to train future investigators to characterize human genetic variation and its phenotypic implications. The research may be either direct studies of human traits or studies of animal models of human traits. The second goal is t
Training Program on Genetic Variation and Human Phenotypes
This program will train Ph.D. students at The Scripps Research Institute in the principles of evolutionary mechanisms in biological systems, and in the application of those principles in the laboratory to problems of biomedical science. ARRA fu
Predoctoral Training Program in Molecular Evoluation
This administrative supplement will enable support of the tuition and stipend of a student in the Computational and Systems Biology (CSB) Ph.D. Program, helping the program to maintain a critical mass of at least 6 students in each entering cla
Graduate Training in Computational and Systems Biology
Purchase the equipment and provide supplemental instruction to build skills in reading for comprehension, writing, analyzing and representing scientific data.
San Francisco State University MARC U*STAR Program Supplement
Through a carefully monitored system of support, instruction, advisement and guidance, undergraduate students prepare for a career in biomedical research. Students receive intensive training and oversight to ensure success and persistence in g
NORTH CAROLINA AGRICULTURAL AND TECHNICAL STATE UNIVERSITY
ARRA Supplement for the NC A & T MARC U STAR Grant.  The purpose of this supplement  is to intensify our efforts to increase the number of minority students at NC A & T who will pursue research training and careers in biomedical research. Fundi
ARRA Supplement for the NC A & T MARC U STAR Grant
The proportion of persons living with HIV/AIDS who are over 50 rose to 22.5% of all cases in 2004, and with the increasing use of Highly Active Antiretroviral Therapy (HAART), more than nearly three-quarters of HIV-infected individuals over 50
The Centers for Innovative Research to Control AIDS (CIRCA) Clinical Trial Unit (CTU) at Columbia University Mailman School of Public Health (MSPH) was established to conduct HIV prevention studies in New York City and New Jersey and to focus o
Centers for Innovative Research to Control AIDS
The purpose of the administrative support supplement is to support the work of HPTN 061 by providing research infrastructure. The purpose of this study is to determine the feasibility and acceptability of a multifaceted intervention among Black
Administrative Supplement to Support Participation In HPTN 061:  A Feasibility Study Of A Community-Level, Multi-Component Intervention For Black Men Who Have Sex With Men.
PUBLIC HEALTH FOUNDATION ENTERPRISES, INC.
The San Francisco Vaccine and Prevention Unit (SFVPU) provides scientific leadership, capacity to recruit study volunteers into vaccine and non-vaccine prevention trials, innovative methods for community engagement in research, and mentorship o
San Francisco Vaccine and Prevention Unit:  CTU Supplement
This proposal includes two components to increase the pace of discovery in our project titled 'Viral Triggers of Alloimmunity and Autoimmunity in Pediatric Lung Transplantation' (1U01AI077810-01), address the economic stimulus priorities, and p
VIRAL TRIGGERS OF ALLOIMMUNITY AND AUTOIMMUNITY IN PEDIATRIC LUNG TRANSPLANTATION
Correlative studies for a Phas I Dose Escalation Study of the Sonic Hedgehog Smoothened Antagonist GDC-0449 (NSC # 747691) Plus Pan-Notch Inhibitor RO4929097 (NCS # 749225) Administered in Patients with Breast Cancer.
EARLY CLINICAL TRIALS OF NEW ANTI-CANCER AGENTS
This proposal responds to RFA-CA-07-505 'The American College of Radiology Imaging Network' and addresses the needs of ACRIN's Biostatistics and Data Management Center (BDMC). This proposal is submitted in coordination with a proposal from the
BIOSTATISTICS DATA MANAGEMENT CENTER FOR ACRIN
This is a request to supplement our parent award, which is to discover and develop biomarkers for the early detection of liver cancer and hepatitis, with funds from American Recovery and Reinvestment Act as in NOT-OD-09-056.  In the parent gran
This supplement award supports Accelerating Clinical Trials of Novel Oncologic Path Ways (ACT NOW) program for Protocol ADVL0911, which is a Phase I Dose Escalation Study of Seneca Valley Virus (SVV-001), a Replication-Competent Picornavirus, i
Children's Oncology Group Phase 1/Pilot Consortium
The Siteman Cancer Center (SCC) Program for the Elimination of Cancer Disparities (PECaD) is a multidisciplinary community-focused program established to eliminate pervasive disparities of cancer education, prevention, and treatment. The SCC Se
PROGRAM FOR THE ELIMINATION OF CANCER DISPARITIES PECAD
NPCC is proposing to adopt Cancer 101 as one of its outreach and education activities. We will expand and update the Cancer 101 curriculum to reflect recent developments in cancer science, prevention, and treatment. We will also explore new way
REGIONAL NATIVE AMERICAN COMMUNITY NETWORKS PROGRAM
Improving Patient Outcomes Through System Navigation Supplement - Build on the objectives of the parent Patient Naviation award through increasing education for the patient navigators and the community health educator.  In addition, develop new
Improving Patient Outcomes Through System Navigation
Emerging Infections Program (EIP) Vaccine Effectiveness:  13-valent Pneumococcal Conjugate Vaccine (PCV13), Quadrivalent Meningococcal Conjugate Vaccine (MCV4) and Human Papilloma Virus Vaccine (HPV) - For PCV13, funds will be used to evaluate
Emerging Infections Program (EIP) Vaccine Effectiveness
In this proposal, the California Department of Public Health (CDPH); selected local and county health departments; the University of California, Berkeley School of Public Health (UCB SPH); and other partners request additional support for the C
This is an ARRA supplement to our currently-existing Emerging Infections Program (EIP) cooperative agreement (project period ends on December 30, 2011). With this supplemental funding, CDC is proposing to evaluate the effectiveness of 2 vaccine
This grant provided a summer resaerch experience for three undergraduate students in health-related scientific research.  The goal of this project is to develop a personal, self-contained circadian light and activity measurement device to corre
Light Measuring Device for Correcting Circadian Disruption
Principal Investigator/Program Director (Last, first, middle): Miller, Josef, M. RESEARCH & RELATED Other Project Information 1. * Are Human Subjects Involved? l Yes m No 1.a. If YES to Human Subjects Is the IRB review Pending? l Yes m No IRB A
MICRONUTRIENT INTERVENTION TO REDUCE NOISE-INDUCED HEARING LOSS
Look AHEAD is a multi-center randomized clinical trial to determine the long-term impact of weight loss on cardiovascular morbidity and mortality in over 5000 overweight individuals with type 2 diabetes. Participants were randomly assigned to
Health Outcomes of Weight loss: Look AHEAD -Action for Health in Diabetes
Look AHEAD is a multi-center randomized clinical trial to determine the long-term impact of weight loss on cardiovascular morbidity and mortality in over 5000 overweight individuals with type 2 diabetes.  Participants were randomly assigned to
Look AHEAD: Action for Health in Diabetes
Acute liver failure is a rare but devastating disease that has been studied for 11 years by our established consortium of 23 academic centers.  We now propose an administrative supplement to support more intensive management of all aspects of t
Multi-Center Study of Acute Liver Failure in Adults - ARRA Stimulus Admin Suppl
These supplemental funds are being used to improve both event ascertainment collection and retention efforts at the University of Illinois at Chicago (UIC) Chronic Renal Insufficiency Cohort (CRIC) Study Clinical Center.  UIC has enrolled 521 p
chronic renal insufficiency Cohort study
The primary aim of this Administrative Supplement proposal is to provide funding for study coordinator salary support at CKiD participating sites. The ability to secure the dedicated time of coordinators well trained in carrying out the CKiD pr
Chronic Kidney Disease in Children (CKiD
The NIDDK provides funding to four different basic science consortia.  Each of these groups has established an informatics infrastructure, but has done so independently.  This poses major limitations for the NIDDK since there is no direct way f
Coordinating Center for Beta Cell Biology Consortium
The overall goal of the Hemodialysis Fistula Maturation Consortium (HFMC), a U01-funded partnership of NIDDK with six Clinical Centers (CCs) & a Data Coordinating Center (DCC), is to better understand the causes and consequences of arteriovenou
VASCULAR STRUCTURE AND FUNCTION IN ARTERIOVENOUS FISTULA MATURATION
Many arteriovenous fistulas (AVFs) suffer thrombosis or fail to mature and become usable. The Univ. of Utah will participate as a Clinical Center to conduct a prospective multi-center observational cohort study, investigating factors associated
MATURATION OF HEMODIALYSIS ARTERIOVENOUS FISTULAS
The overall objective of the two proposed Center Collaborative Research Projects is to fill specific gaps in our knowledge of the impact of in utero, early postnatal and pubertal environmental exposures on mammary gland development at the cellu
Breast Cancer and the Environment Research Center
DESCRIPTION (provided by applicant): One critical need for the development of reliable docking and scoring (d/s) is a large dataset containing high quality experimental protein-ligand complex structures, together with accurate binding affinity
PUBLIC/PRIVATE COLLABORATION FOR HIGH-QUALITY PROTEIN-LIGAND DATA
HIV infection in the US occurs disproportionately among racial/ethnic minority youth in urban areas. The Adolescent Trials Network for HIV/AIDS Interventions (ATN) has developed a community-based primary HIV prevention infrastructure in 13 citi
DESCRIPTION (provided by applicant): Pelvic floor disorders, such as urinary incontinence, pelvic organ prolapse, and fecal incontinence, are common and significant health-related problems for women in the United States. Outcomes following surg
PELVIC FLOOR DISORDERS NETWORK-DATA COORDINATING CENTER
DM-STAT serves as the Data Coordinating Center (DCC) for the Collaborative Programs of Excellence in Autism (CPEA)/Studies to Advance Autism Research and Treatment(STAART) Networks.  The DCC intends to perform the analysis of the primary S002 (
Although the prevalence of 'family-friendly' policies in US workplaces has increased dramatically in recent years, few have been studied using scientifically sound designs. To address this critical gap, the NIH and the CDC formed the Work, Fami
Center for Work-Family Stress, Safety and Health
This application is a request for an administrative supplement for our parent grant, U01 HD060496, “Identification of Small Molecule Contraceptives that Target the Male Germline” from the Eunice Kennedy Shriver National Institutes of Child
IDENTIFICATION OF SMALL MOLECULE CONTRACEPTIVES THAT TARGET THE MALE GERMLINE - PARENT GRANT 1U01HD060496
The generation of complete or nearly complete eukaryotic genome sequences has produced an explosion of insights into the coding potential and evolution of genomes. However, we have less information about how key processes involving DMA are regu
Genome-Wide Mapping of Chromosomal Proteins in Drosophilia
Our modENCODE parent grant U01-HG004261 is aimed at annotating the functional short regulatory RNAs of Drosophila melanogaster using deep sequencing methodology. These include known classes of Argonaute-bound RNA such as microRNAs, small interf
Annotation of the Small RNA/micro RNA component Drosophila Genome
The C. elegans transcriptome group of the modENCODE project has applied second-generation sequencing of cDNAs from a variety of worm stages, sexes and growth conditions to greatly improve the annotation of the C. elegans genome.  With supplemen
Global Identification of transcribed elements in the C. elegans genome
Scope of the overall project and anticipated contribution of the requested supplement: Scope of parent grant: The discovery of putative causal (genuine) genetic variants associated with complex diseases and traits, such as cardiovascular diseas
Epidemiology of putative genuine genetic variant:  The Women's Health Intiative
is funded to use DNA samples from the National Health and Nutrition Examination Surveys for characterizing genetic variations identified through genome-wide association studies (GWAS) and candidate genes as being associated with common, comple
Epidemiologic Architecture for Genes Linked to Environment (EAGLE)
The Philadelphia Department of Public Health (PDPH) in collaboration with the Centers for Disease Control and Prevention (CDC) will conduct a matched, case-control study to examine the incremental effectiveness of the 2-dose varicella vaccinati
American Recovery and Reinvestment Act (ARRA) – Section 317 Immunization Program:  Strengthening the Evidence Base Measuring Effectiveness of Two Doses of Varicella Vaccine – U01
Measuring the effectiveness of two doses of varicella vaccine in Los Angeles County. Grant application to ARRA Section 317 Immuinzation Program Strengthening the Evidence Base Measuring Effectiveness of Two Doses of Varicella Vaccine (U01)  Mea
Measuring Effectiveness Two Dose Varicella Vaccine LA
A Multilevel HIV-Prevention Strategy for High Risk
The overarching aims of the REGARDS project are to advance the understanding of the causes for the excess stroke mortality among residents of the Southeastern Stroke Belt (SB) and among African Americans (AA) regardless of residence. To accompl
ETIOLOGY OF GEOGRAPHIC AND RACIAL DIFFERENCES IN STROKE
Generation of functionally competent B lymphocytes is essential for producing antibodies (also called immunoglobulin, B cell receptor), the molecules mediating body's humoral immunity against pathogens and tumor cells. Abnormal B cell function
Transcriptional Repression and Activation by YY1
Inflammation is a process essential for host defense and tissue repair. However, exuberant defense may cause pathogenic changes leading to vascular diseases such as atherosclerosis. This is because multiple cytokines are involved in the process
Inhibiting JNK A New Anti-Infammatory Strategy
Prince William County (PWC) will expand and enhance its community corrections program by creating new positions equivalent to two full time employees (2 FTEs).  The new positions include 3 part-time program officers (1 FTE) and one full-time me
ND 1 - From W Jct I-94 N To Jct ND 26-DAZEY
'The COPS Hiring Recovery Program (CHRP) provides funding directly to law enforcement agencies to hire or rehire career law enforcement
To supply pediatric vaccines for CDC's Vaccine for Children contract.
Jamestown Community Center-Blyn Rd Trail
'The JAG Hiring Recovery Program provides the funding directly to law enforcement agencies to hire and/or rehire career law enforcement officers in an effort to create and preserve jobs, and to increase their community policing capacity and cri
Preserve Current Commissioned Officers Staffing Levesl in the Department
Interstate Bridge Maintenance, South (PE)
Interstate Bridge Maintenance, North (PE)
Pavement & Rehabilitation, South I-III, 2009
The Grant will enable the weatherization of elegible dwelling units in Essex County. The weatherization conservation measures to be undertaken will provide immediate and long range relief of New Jersey's elegible clients by lowering high fuel b
Cooperative State Research, Education, and Extension Service
The purpose of this project is to form a National TAAF Training Coordination Center (TAAF Center) to deliver Trade Adjustment Assistance for Farmers technical assistance to producers of eligible commodities. The TAAF Center will design a rapid
National TAAF Training Coordination Center
Purchase equipment inclduing K9 cage, flashlights, radio rack, digital camera & camcorder, surveillance equipment, computer and communications upgrade
To purchase a Multi- propuse k-9 and quipment as well as train an officer for k-9 duty.
Clarksburg Police Department - K-9 Program
Grant funds to be used for equipment and information systems for criminal justice law enforcement programs.
The Philippine Mollusk Symbiont ICBG (PMS ICBG) project links a biodiversity survey of marine mollusks in one of the world's hotspots of diversity, with drug discovery and enzyme bioprospecting aimed at bacterial symbionts of mollusks. Mollusks
DIVERSE DRUG LEAD COMPOUNDS FROM BACTERIAL SYMBIONTS IN TROPICAL MARINE MOLLUSKS
FRONTIER SCIENCE & TECHNOLOGY RESEARCH FOUNDATION, INC.
The E4508 randomized phase II clinical trial will evaluate the combination of chemotherapy with EGFR inhibition, IGF-1R inhibition or both. Although the clinical study accrual rate is estimated at 12 months, there will be an interim toxicity an
Eastern Cooperative Oncology Group Operations Office - ACTNOW Protocol E4508
The main objective of this grant to provide support for the integration, standardization, and coordination of standardized information-technology (IT) tools and operational procedures for the Radiation Therapy Oncology Group (RTOG).  Specifical
RTOG ADOPT ARRA Program-Integration of OPEN, CTCAEv4 and eCRF Upgrades with the RTOG Clinical Trials Management System
The Gynecologic Oncology Group (GOG) is the foremost multidisciplinary cooperative clinical trial research group devoted to the study of gynecologic malignancies. Since its inception in 1970, the GOG has been a recognized leader in the developm
The Southwest Oncology Group is an adult, multi-disease, multi-modality clinical cancer research organization with 35 Member Institutions, 29 Community Clinical Oncology Program (CCOP) institutions, including 7 Minority-Based CCOPs, 27 Urologic
SOUTHWEST ONCOLOGY GROUP - OPERATIONS OFFICE
This award is designed to fund a research nurse navigator program with the goal of accelerating the tempo of scientific research by increasing registration and patient recruitment  to national cooperative group research trials and allow for job
Michigan Cancer  Research Consortium CCOP
The Studies of the Ocular Complications of AIDS Research Group is dedicated to understanding and improving the outcomes of the ocular complications of AIDS. The Longitudinal Study of the Ocular Complications of AIDS (LSOCA) is a prospective coh
STUDIES OF OCULAR COMPLICATIONS OF AIDS - CHAIRMAN'S OFFICE
The Collaborative Observational Study of Myopia in COMET Children (COSMICC) is a longitudinal study that has followed the cohort of children who participated in the Correction of Myopia Evaluation Trial (COMET. Currently, at an average age of 1
ARRA: Collaborative Observational Study of Myopia in COMET Children 2-Coordinating Ctr
This grant application is a companion to the application submitted by Dr. Mark Kupersmith for the Neuro-Ophthalmology Research Disease Investigator Consortium (NORDIC). This application describes a Data Coordination and Biostatistics Center (D
DATA COORDINATION AND BIOSTATISTICS CENTER FOR THE NORDIC NETWORK
The North Carolina Collaborative Pediatric Pharmacology Research Unit (NCC-PPRU) will be composed of personnel from Duke University and the University Of North Carolina (UNC). The NCC-PPRU will help develop new medications with pediatric indica
North Carolina Collaborative PPRU Network
DESCRIPTION (provided by applicant): Pelvic floor disorders are common, bothersome, and inadequately treated. The overarching aim of the investigators from the proposed University of Utah Pelvic Floor Disorders Clinical Site is to improve women
DESCRIPTION (provided by applicant):  The objectives and aims of this application are for San Diego to become the first western United States clinical site in the Pelvic Floor Disorders Network (PFDN). The San Diego Clinical Site is a collabora
DESCRIPTION (provided by applicant): There has been a long standing research and clinical collaboration between Urology and Reproductive Endocrinology at the University of Michigan. This proposal describes the qualifications and experience of t
COOPERATIVE MULTICENTER REPRODUCTIVE MEDICINE NETWORK (U10)
This project represents a Recovery Act Administrative Supplement for parent grant 1U10HD055942-01: ?Letrozole Therapy for IVF/ET: Effects on Multiple Pregnancy and Treatment Burden?. The parent grant established the University of Texas Health S
LETROZOLE THERAPY FOR IVF/ET: EFFECTS ON MULTIPLE PREGNANCY AND TREATMENT BURDEN
This project would entail expanding the current 12-color panels we have in two ways:  1) to create new 12-color panels that in addition to 6-8 anchor markers that recognize the main populations also incorporate markers of activation, inhibition
AUTOIMMUNITY CENTER OF EXCELLENCE - ROCHESTER
The overall goal of our current U19 grant is to understand how a successful vaccine, the live yellow fever virus (YFV-17D) vaccine, induces long-term immunological memory and protective immunity in humans. The YFV-17D vaccine is recommended by
VACCINE INDUCED IMMUNITY IN THE YOUNG AND AGED
Our primary objective is to obtain further information about the mechanisms of acute episodes of asthma both in adults and children. This requires knowing details of the patients, including exhaled nitric oxide (FeNO), exhaled breath pH, eosino
This proposal seeks a renewal of funding for the United States based International Breast Cancer Study Group (IBCSG) Statistical and Data Management Center, a resource that contributes to International-US collaboration in the following areas: Â
IBCSG Statistical Center - A Breast Cancer Study Resource
New, sensitive and specific diagnostic and prognostic tests for early detection of cancer are desparately needed. This award aims to significantly expand the number of novel cancer-related assays that our project will develop. A second componen
Measuring Cancer Biomarker Candidates by Targeted MS & Ab Enrichment
Our long-term objectives are to continue to provide outstanding phenotyping services to the scientific community, provide a resource of expertise and knowledge for consulting on research projects, and encourage the collaboration among researche
MMPC: Diabetes and Diabetic Complications
National Center for Canine Models of Duchene Muscular Dystrophy   ARRA This administrative supplement of $95,000 will allow purchase of equipment to support our grant, 1 U24 NS059696-01A1, which established the National Center for Canine Models
National Center for Canine Models of Duchene Muscular Dystrophy   ARRA
DESCRIPTION (provided by applicant): We propose establishing the UCSC ENCODE Data Coordination Center to collect, organize, store, and provide access to data from the ENCODE project and other related projects, based on the well-established UCSC
The UCSC ENCODE Data Coordination Center
Activity A: Coordination and Reporting of State HAI Prevention Efforts - Objectives of Activity A are to develop a sustainable state plan to collect HAI data and report aggregated state progress toward national HAI prevention targets. By Decemb
Epidemiology and Laboratory Capacity - ARRA - HAI
The Department of Health (VDH) has received a grant of $830,600 from the Centers for Disease Control and Prevention to support efforts to prevent healthcare-associated infections in Vermont. These are ARRA funds available for expenditure betwee
This ARRA funding will enable the Massachusetts Department of Public Health (MDPH) to enhance identification and investigation of all cases of meningococcal disease and all cases of invasive Haemophilus influenzae disease in the Commonwealth.
The goal of the Epidemiology and Laboratory Capacity for Infectious Diseases Grant is to build and help sustain the state's capacity for preventing Healthcare Associated Infections (HAI). This grant will address coordination and reporting and H
Epidemiology and Laboratory Capacity for Infectious Diseases
The prevention and control of vaccine preventable diseases is a major priority for the Philadelphia Department of Public Health (PDPH).  Invasive meningococcal disease, pertussis, and invasive Haemophilus influenzae serotype b infections (Hib)
American Recovery and Reinvestment Act (ARRA)-Strengthening the Evidence Base Epidemiology and Laboratory Capacity for Infectious Diseases (ELC) Evaluation of Meningococcal Conjugate Vaccine and Other High-Priority Vaccine Preventable Diseases
The Illinois Department of Public Health (IDPH) collaborated with four authorized health jurisdictions (Cook, DuPage, Kane and Lake) serving the residents of the greater metropolitan Chicago area (excluding Chicago). This collaboration  establi
The Epidemiology and Laboratory Capacity (ELC) program coordinates and implements prevention activities in two or more Action Plan targets. This includes increased reporting to CDC and enhancing and enlarging current HAI prevention activities.
The purpose of this Recovery Act Healthcare – Associated Infections (HAI) supplement is to address the Health and Human Services (HHS) Action Plan by using the existing Epidemiology and Laboratory Capacity (ELC) cooperative agreement to build
Rotavirus is not a nationally reportable disease and clinicians do not routinely test for rotavirus among pediatric cases of acute gastroenteritis, so active surveillance for rotavirus gastroenteritis is considered a valuable resource. Addition
Strengthening the Evidence Base Epidemiology and Laboratory Capacity for Infectious Diseases (ELC) Rotavirus Vaccine Effectiveness
These funds are intended to reduce preventable Health Care associated infections through State health department efforts to prevent HAI's including leveraging the National Health Care Safety Network to support the dissemination of HHS evidence
This Recovery Act supplement to the Epidemiology and Laboratory Capacity for Infectious Diseases (ELC) cooperative agreement includes three major activities.  Activity A is the basic staffing and coordination to draft the State Healthcare-Assoc
Epidemiology and Laboratory Capacity for Infectious Diseases - ARRA - HAI
) is a research consortium comprising 28 projects clustered within six programs. The Center also features five core facilities that serve the entire region. All four states (AZ, CA, HI, and NV) of Region IX are represented among the 21 educatio
Pacific Southwest RCE for Biodefense & Emerging Infectious Disease Research
This supplement to Meharry Medical College's cancer research center grant  provides support to hire a physician scientist such as a surgical oncologist with experience in breast,  prostate, or colon cancer research.
MMC and VICC: Partners in Eliminating Cancer Disparities
The purpose of this supplement is to: 1. To employ a CHE (one of two, based at each partner institution) to increase the LlU/CU U54 Partnership's cancer education and outreach efforts to our communities and to train community health workers (CH
Cancers in Older Minority Populations: Caribbean American Emphasis
This supplemental award provides funds to support project 2 and to accelerate the tempo of the parent grant. There are two specific tasks: Task 1: Systematically study and optimize the circulation lifetime of drug delivery motherships and nanop
CENTER OF NANOTECHNOLOGY FOR TREATMENT, UNDERSTANDING, *
The Goal of this supplement will be to adding both personnel and equipment.It will aid in increasing output by reducing the time spent on complex procedures and increasing experimental yield.
Center for Reproductive Research at Northwestern University
This is a partial award for the consortium with the Hugo W. Moser Research Institute at Kennedy Krieger effective 9/30/09.  These supplemental funds are intended to accelerate the pace of biomarker discovery for FSHD therapeutics and will be ta
This award is part of the NHLBI basic and translational research program in sickle cell disease
Washington Area Basic and Translational Research Program
This is a revised U56 application to the National Cancer Institute to support the planning and development of a 'Comprehensive Minority Institution and Cancer Center Partnership' between the University of Maryland Eastern Shore (UMES--a minorit
Cooperative Planning Grant for Comprehensive Minority
The goals of this supplemental award are to enhance the research workforce development and dissemination activities of the University of California Davis (UCD) Clinical and Translational Science Center (CTSC) and to enhance use of workforce res
Subproject for Institution # 06-000931: UC Davis Clinical and Translational Science Center - UL1
The CTSA Consortium Strategic Goal #1 seeks to improve clinical and translational research management capability. The administrative and regulatory infrastructure supporting clinical research is often a key determinant of the success of funding
Mayo Clinic Center for Clinical and Translational Research
project is an important initiative that will further increase awareness about the community based participatory research (CBPR) approach to public health and help foster future research.  In order to foster community engagement and CBPR, this
University of Pittsburgh Clinical and Translational Science Institute
The Collaborative to Build Community Capacity for Research is a joint project of Vanderbilt University Medical Center, Meharry Medical College, and Tennessee State University which proposes to create sustainable mechanisms and processes to deve
The Vanderbilt Institute for Clinical and Traslational Research (VICTR)
This is a collaborative community engagement ARRA supplement request. There are over 80,000 clinical trials conducted each year in the US, and yet, less than 1% of the population participates in them. The so-called ?leaky pipe of clinical trial
While the Washington University Institute of Clinical and Translational Sciences (ICTS) has made significant progress in deploying comprehensive resources to facilitate research, the ICTS  is still hampered by inefficient communication and coor
TThe Hunter School of Nursing, City University of New York (HCSON) is an active partner of the Weill Cornell Medical Center Clinical and Translational Science Center (CTSC), a cluster of institutions forming a unique and cohesive biomedical com
Clinical and Translational Research Award - Community Engagement with Nursing and Science (CENS)
The University of Washington, the ITHS' home institution, serves as the medical school for five states -- Washington, Wyoming, Alaska, Montana, and Idaho (WWAMI), providing the ITHS with enormous potential for collaboration and development of t
ITHS Support to Develop Regional Translational Research Capacity
This Administrative Supplement will enable an extensive collection of valuable medical images obtained during clinical care to be discoverable by the scientific community for research by using the i2b2 framework to support queries for medical i
Harvard Clinical and Translational Science Center- NCRR ARRA Supplement- Translational (Imaging)
The proposed Administrative Supplement for Collaborative Community Engagement Research will provide additional support to the NCRR-funded Indiana CTSI and 10 other collaborating CTSA centers and community partners to develop new resources that
Indiana Clinical and Translational Science Institute (UL1)
The vision of the University of Cincinnati Academic Health Center (AHC) Institutional CTSA is to create an environment to facilitate translating discoveries to clinical application. Our new academic home for clinical and translational research,
NCRR ARRA Administrative Supplement: Workforce Development and Dissemination
US 2 - From 3 Miles West of Jct 52 East TO 1 Mile West Jct 83
TOLSON, SIMPSON & ASSOCIATES, CONSULTING ENGINEERS, INC.
Initial Site Visit & Compliance Report at Bon Secour Nunley House
Cost Estimating Services for the MATOC Solicitation and  TaskOrder for Tennessee NWR, Mammoth Spring, Arkansas NWR, Coastal NC NWR
GENESEE VALLEY GREENWAY TRAIL BRIDGE OVER THE RIVER AT RT 36
LOIS DRIVE BRIDGE WEST OF TAMMI DR-TAVARES REPLACE BRIDGE #114052
RT 96 FROM I490 TO THE VILLAGE OF PITTSFORD MBC
This grant award provides funding under the American Recovery Reinvestment Act of 2009 to the State of Pennsylvania through the Pennsylvania Infrastructure Investment Authority (“PENNVEST”) to capitalize its revolving loan fund for the fina
NE 44TH STREET CITY OF LIGHTHOUSE POINT SIDEWALKS
ROUTE 261 FROM ROUTE 104 TO ROUTE 18 VPP
CR 589(DELTONA BLVD) FM CR 574/SPRING HILL DR TO PHILATELIC DR
BURWELL RD FR PASCO CO/L (LACOOCHEE) TO SR 50 (CORTEZ BLVD)
CR 491 (LECANTO HWY) FROM N OF PINE RIDGE BLVD TO SR 200
UNITED STREET FROM PEARL STREET TO GEORGE STREET
WEST 29TH STREET FROM SR 25/OKEECHOBEE RD. TO WEST 4TH AVENUE
PALM AVENUE FROM 45TH STREET TO 47TH STREET
CR 129/LAKE JEFFREY FROM: SR 10/US 90 TO: CSX RR
CR 231 FR: REGIONAL MEDICAL CENT TO: BRADFORD COUNTY LINE
The Phoenix CeaseFire project applied for a funding under Category I: Comprehensive Community-Based Data-Driven Approaches to Preventing and Reducing Violent Crime. Goals and objectives applicable to the project:  Goal:  To reduce the level of
BJA FY 09 Recovery Act Edward Byrne Memorial Competitive Grant Program: Hiring of Civilian Law Enforcement Personnel (Support Personnel).  The grant project funds three full-time crime analysts in the Santa Clara County Sheriff's Office. One cr
Crime Analysis Reduction and Eradication
'The Recovery Act Edward Byme Memorial Competitive Grant Program (Byme Competitive Program) will help communities improve the capacity of state and local justice systems and provide for national support efforts including training and technical
Under category 1, Fund for the City of New York will use the FY 2009 Recovery Act Byrne Competitive funds to support the Crown Heights Community Mediation Center with the Crown Heights CeaseFire (CHCF) Program.
BJA FY09 Recovery Act Edward Byre Neighborhood Probation and Parole Re-Entry Supervision Program.
This grant establishes the Hennepin County DNA Property Crime Initiative which will significantly expand the use of DNA testing in property crime investigations throughout the county and reduce the backlog of DNA property crime cases currently
Reduce DNA Backlog in Sheriff's Crime Lab
This award is funded under the American Recovery and Reinvestment Act of 2009, Edward Byrne Memorial Competitive Grant Program, Category V: Enhancing Forensic and Crime Scene Investigations. Grants funds awarded to NYC Office of Chief Medical E
Edward Byrne Memorial Competitive Grant Program - Enhancing Forensic and Crime Scene Investigation
Our plan is to improve the ability of the State Police Crime Laboratory (LSPCL) to provide timely forensic analysis to law enforcement, in significantly reducing the backlog of samples waiting for DNA and forensic analysis.  Finally, to increas
Washoe County Sheriff's Office Community Work Program
STATE PATROL, WASHINGTON STATE DEPARTMENT OF THE
Advancing Active Analysis in the Washington State Patrol - Produce context-sensitive analysis in support of data-driven strategies in an evidence-based “Data-Driven Approaches to Crime and Traffic Safety” (DDACTS) structure that reduces vio
Advancing Active Analysis in the Washington State Patrol
The city of Tacoma will use grant funds to continue comprehensive community-based,data-driven approaches to prevent and reduce violent crime. The city's Law Enforcement Support Agency (LESA)is responsible for providing integrated 911 communicat
LARIAT (LESA Accelerated REsponse using Integrated Analysis & Technology
This proposal requests support to continue and extend the Bureau of Justice Assistance (BJA) training and technical assistance (TA) program known as the Drug Market Intervention (DMI) Training Program. This will be achieved through two cycles o
Drug Market Intervention Program ? Training, Technical Assistance, Public Awareness and Outreach
Assign a full time investigator to investigate narcotic crimes and gang activity in the area of St. James and Watonwan County.
BJA FY 09 Recovery Act Rual Law Enforcement Assistance: Combating Rural Crime
Under Category I, the Nevada City Police Department will provide additional staff to assist in preventing and responding to crime in the city.  This will be accomplished by creating one new police officer position, filling two vacant positions,
Restoring Police Department Deployment Levels
SCINT is a multi jurisdictional narcotics team. SCINT has been in operation for 21 years serving the citizens of the South Western Oregon coast. This area is composed of 3,200 square miles and a population of 90,000.  We have lost over half of
Columbia County improving Jail Mental Health Services Project.This will increase our capacity to be able to provide safety and security for civilian contractors to enter our facility and provide mental health services to our inmates.  They will
2009-11 Columbia County improving Jail Mental Health Services Project
The Justice Information Sharing Grant will allow Grand Traverse Band (GTB) to create data sharing capability to share criminal history information within GTB and with other Michigan Tribes.  GTB will acquire case tracking software, hire a Proje
The Assistance to Rural Law Enforcement to Combat Crime and Drugs Program, Under Category I, the City of Portsmouth, through the police department, will improve intelligence collection, compilation, and analysis of crimes by hiring three police
Title: Investigations Division to Combat Methamphetamine Production and Delivery. Award funds purchase of vehicles and equipment to form an Investigations Division with in the Sheriff's Office of Decatur County.
Investigations Division to Combat Methamphetamine Production and Delivery
Project Rope: Release on Pretrial Evaluation
Hire two patrol deputies to expand the current multi-agency drug task force.
To augment the Bureau of Investigation and Intelligence (BII) Investigative Support Teams (IST) program and the Intelligence Operations Program (IOP) with special agents and criminal intelligence specialists that will focus their efforts on the
Mortgage Fraud in Rural Areas of California Category: Category I - Combating Rural Crime
The goals of the project are: to increase the number of arrests for computer-related offenses; to increase the number of convictions for computer-related offenses, with special emphasis on crimes against a victim who is a minor; to increase the
Crime Scene Unit Implementation This project is designed to implement a full time crime scene unit comprising of two crime scene analysts, one full time administrative assistant and one grants administrator.  The goals of the crime scene unit a
The Morehouse Parish Sheriff's Office plans to utilize grant funding to create 5 new correctional officer positions, preserve 10 correctional officer positions that would have been eliminated due to budget constraints, and fund one full time co
Enhancing jail operations by creating and preserving employment positions and improving training programs for correctional officers
The Lee County Sheriff's Office is located in central North Carolina and is requesting $235,700 to support our proposed project called, 'Lee's Recovery Enhancment for Detention.' The grant is covered under category III, Enhancing Rural Detentio
Lee's Recovery Enhancement for Detention
2009 Rural Law Enforcement Grant Detective /Metro
Kanabec County Sheriff's Office goal is to hire seven Correctional Officers, two Food Service Personnel, one Maintenance Person and one Jail Sergeant to open our new Kanabec County jail January of 2010. Our Major deliverables and coordination p
The Assistance to Rural Law Enforcement to Combat Crime and Drugs Program helps rural states and rural areas prevent and combat crime, especially drug-related crime, and provides for national support efforts, including training and technical as
Vermont's Rural Law Enforcement to Combat Crime and Drugs Grant: Category I Combating Rural Crime
FUNDING FOR 1 POLICE OFFICER, 1 POLICE CLERICAL STAFF, & 1 INFORMATION SYSTEMS TECHNICIAN & 1 MOBILE RECORDS MANAGEMENT SYSTEM MODULE, 15 SQUAD CAR COMPUTERS, 15 DOCKING STATIONS, 15 PRINTERS, CABLES, 28 CELLULAR AIR CARDS
ASSISTANCE TO RURAL LAW ENFORCEMENT  FACILITATING RURAL JUSTICE INFORMATION SHARING INITIATIVE
The purpose of this  project is to retain an Information Technology Specialist Job in Pend Oreille County to facilitate Rural Justice Information Sharing.  Deliverables of the proposed project will be: 1. Hire an Information Technology Speciali
Retain Information Technology Specialist Job
Rural Law Enforcement Drug Interdiction Grant -
To develop and deliver training for the nation's rural law enforcement agencies, with priority given to communities ineligible to receive direct allocations of Byrne JAG funds.
Rural Law Enforcement Training Initiative
Compensate victims of crimes for lost wages, lost support and out-of-pocket medical expenses as result of the crime.
FY 09 Recovery Act-Victims of Crime Act (VOCA) Victim Compensation Formula Grant Program
Recovery Act-OVC fy09 VOCA Victim Compensation Formula Grant Program.  This is to compensate victims of violent crime.
Recovery Act-OVC fy09 VOCA Victim Compensation Formula Grant Program
CRIMINAL JUSTICE COORDINATING COUNCIL, GEORGIA
OVC FY 09 VOCA Victim Assistance Formula Grant.  States and territories use State Crime Victim Assistance funds to support community-based organizations that serve crime victims. Organizations provide services such as crisis intervention, couns
FINANCE AND ADMINISTRATION, ARKANSAS DEPT OF
Services under this grant program will (1) respond to the emotional and physical needs of crime victims; (2) assist primary and secondary victims of crime to stabilize their lives after a victimization; (3) assist victims to understand and part
The Recovery Act - OVC FY 09 VOCA Victim Assistance Formula Grant Program award will be used to enhance and expand crime victim assistance services.
This award provides new positions or helps to retain positions lost within the last two years to state and local government agencies, non-profit agencies, tribal, and faith-based organizations that provide direct services to victims of crime in
This grant is to create more positions at the Maine Computer Crimes Task Force. There will be two additional people to work in the area of child exploitation, investigations and related prosecutions and one Computer Forensic Analyst working hal
Internet Crimes Against Children (ICAC) Task Force - ME
The Recovery Act Internet Crimes Against Children Task Force grant funding will be utilized to support a percentage of the employment of current members of the primary grantee, the Burlington Police Department and will also be utilized support
There continues to be dramatic increases in sexual child abuse and child exploitation facilitated by the use of computer technology and the Internet. The Maryland Internet Crimes Against Children (MDICAC) Task Force has improved the ability of
The Internet Crimes Against Children (ICAC) Recovery Act grant covers a single project that expands the efforts of the Arizona ICAC Task Force to identify, arrest and prosecute predators who use the Internet to sexually exploit children.  The I
Expansion of the Internet Crimes Against Children Unit
The Internet Crimes Against Children Task Force for the Southern Part of Texas addresses the continuing problem of online distribution of child pornography and online solicitation. OAG prosecutors and investigators will provide the necessary su
Internet Crimes Against Children Task Force Program Southern Texas
The National White Collar Crime Center (NW3C) will deliver training and provide technical assistance designed to serve the Internet Crimes Against Children (ICAC) task force agencies. The target audience is law enforcement, prosecutors, and oth
NW3C ICAC Training and Technical Assistance Program
ICAC Task Force Training and Technical Assistance
Among other purposes, the American Recovery and Reinvestment Act provides funds to preserve and create jobs and promote economic recovery and to provide investments needed to increase economic efficiency by spurring technological advances in sc
Geo-Query - Linking Geo-Time Information to Law Enforcement Queries
This research is a collaborative effort between Development Services Group, Inc. (DSG), and the California Department of Corrections and Rehabilitation (CDCR) to conduct a process and outcome evaluation of CDCR’s Global Positioning System (GP
An Evaluation of a Global Positioning System for Monitoring High-Risk Gang Offenders
SEARCH will develop a set of standard service interfaces, along with a default implementation of those interfaces available under an open source license, for entity resolution and correlation.  The service interfaces will conform to the guidanc
Law Enforcement Technology Research and Development: Entity Resolution and Correlation Service Project
APD?s designed the following program to control, reduce, and/or prevent criminal narcotics activity, including drug-related crime and violence, in High-Intensity Drug Trafficking Areas in order to combat criminal narcotics activity stemming fro
Reduce Crime and Narcotics Activity stemming from the southern border of the United States through apprehension of defaulting probationers on probation for drug related offenses.  Outcome 1:  Retain five (5) surveillance officer jobs.  Outcome
Apprehension of defaulting probationers with drug-related offenses
The State and Local Law Enforcement Assistance Program: Combating Criminal Narcotics Activity Stemming from the Southern border of the United States.
BJA FY 09 Recovery Act Combating Criminal Narcotics Activity Stemming from the Southern Border of the United States: Combating Criminal Narcotics Activity along the Southern Border
The Eastern Band of cherokee indians, under Category II, will enhance their detention and law enforcement capacity by funding the construction of a Multi-purpose Justice Center.
BJA FY 09 Edward Byrne Memorial Justice Assistance Grant.  The JAG Program allows states and local governments to support a broad range of activities to prevent and control crime and improve the criminal justice system. JAG grants support to al
Recovery Act - BJA FY 09 Edward Byrne Memorial Justice Assistance Grant Program
The Justice Assistance Grant (JAG) Program permits funding for a broad range of activities to prevent and control crime based on local needs and conditions.  JAG funds may be used for state and local initiatives, technical assistance, training,
2009 PENNSYLVANIA STATE JUSTICE ASSISTANCE GRANT (JAG) STIMU
FY 2009 Recovery Act Justice Assistance Grant Program Recovery Act Funding Goal: Improve the functioning of New Mexico’s criminal justice system, for the purpose of reducing violent crime, and the sale of illicit drugs.
The Indiana Criminal Justice Institute (ICJI) will use their Fiscal Year 2009  Recovery Act Justice Assistance Grant (JAG) award funds to work closely with the Governor's Offices, State Budget Agency and the ICJI Board of Trustees.  They will w
FY 2009 Recovery Act Justice Assistance Grant  Program
The Montana Board of Crime Control will use its Fiscal Year 2009 Recovery Act Justice Assistance Grant (JAG) funds to support local law enforcement and multi-jurisdictional drug task force programs throughout the State.  Programs to be funded i
Montana Recovery Act Edward Byrne - Justice Assitance Grant
2009 Utah Justice Assistance grant (JAG) - ARRA Stimulus grant.   The Utah JAG - ARRA grant will  allocate funding to units of state and local government along with private providers of criminal justice services.  JAG - ARRA funding will awarde
This ARRA project is being implemented in order for the FWS and D and R ranches to work together to restore habitat (approx. 1.296 acres) for the candidate lesser prairie-chicken and other grassland dependednt species.
CENTER OF EXCELLENCE FOR HAZARDOUS MATERIALS MANAGEMENT
This Award (Cooperative Agreement) is being implemented in order for the Service and the Cooperator to work together on privately owned lands for the purpose of improving native short-grass sand scrub, sand dunes, and desert grassland habitats
R2EC-Lesser Prairie Chicken Habitat Restoration
Highway Infrastructure Investment Grant: Transportation Enhancements, Rural Areas with Population under 5K
Highway Infrastructure Investment Grant: Available for Use in Any Area (flexible) , Rural Areas with Population under 5K
Safety and Resurfacing MD 410 to Holton Lane
SR 826/SR 836 FROM N OF SW 8 ST TO S OF NW 25 ST & FM NW 87 TO 57 AVE'S
HOUSING AUTHORITY FOR THE CITY OF LAKE CITY
This ARRA money has been used to re-roof 7 buildings out of 19 buildings.
Capital improvements for public housing units in Malvern Arkansas
Public Housing Capital Fund Stimulus Formula Recovery Act Funded
Modernize Public Housing and provide employment to Construction Workers.
Rehabilitation of units, install HVAC units, site preparation.
To provide technical assistance to Farmers within the EAEC service area (as well as those surrounding areas) in order to expand their current businesses; and to continue to provide services and assistance to beginning and existing small busines
East Arkansas Enterprise Community's Small Business Technical Assistance and Training Initiative
HIGHWAY AND TRANSPORTATION, ARKANSAS DEPARTMENT OF
The Arkansas Highway and Transportation Department will invest American Recovery & Reinvestment Act funds in Arkansas' Public Transportation by purchasing 126 replacement buses for transit providers throughout the State of Arkansas. In addition
544 - (Combo Loan & Grant) Water Only - 09/10 Stimulus
Fort Smith Transit will invest in public transportation by completing the transfer station facility at 200 Wheeler Avenue in Fort Smith, Arkansas, purchase four demand response buses, purchase and install approximately 30 bus shelters, purchase
MCGEHEE-DESHA COUNTY HOSPITAL FOUNDATION, INC.
To purchase an Aquilion 32 Fast Whole Body CT Scanner
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).   Broad-scale investigations of the ecological consequences of changing climate and seasonality in the Arctic are imperative to improving our unde
Timing is everything: seasonality and phenological dynamics linking species, communities, and trophic feedbacks in the Low- vs. High Arctic
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  Of the planet?s ecosystems the Arctic is the most sensitive to climate change. Recent increases in the rate of environmental change in the Arctic
The Arctic is undergoing structural & functional changes that appear to be the result of climate change, including shifts in vegetation distribution, increases in CO2 & CH4 efflux from ecosystems to the atmosphere, and the acceleration of disso
Collaborative Research:  Environmental changes alter the carbon cycle of High Arctic ecosystems:  shifts in the ages and sources of CO2 and DOC
HWY. 49-HWY. 242 (HELENA-W. HELENA) (REHAB)
Asphalt Paving Mixture and Block Manufacturing
This project reconstructs Taxiway D, which is at the primary intersection of Taxiways A, E, & D.  The pavement at this location has failed.  The reconstruction of the Taxiway D will allow Bellingham International Airport (BLI) to meet the curre
Award provideds framework for the US Forest Service and the Leech Lake Band of Ojibwe to work together in providing the resources neede to more efficiently and effectively implement fire management operations, including but not limited to, fire
Dr. Begelman will study the formation and growth of the most massive black holes in the cosmos. These are the powerhouses for the luminous active nuclei that are found at the centers of luminous galaxies. The black holes must grow rapidly, sinc
Formation of Supermassive Black Holes by Direct Collapse
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).The Akamai Workforce Initiative (AWI) is an interdisciplinary project that partners the University of Hawaii Institute for Astronomy, the Center fo
The PI will execute an integrated research plan to address several problems that are at the forefront of supermasslve black hole research: 1. How supermassive black holes merge, 2. How supermasslve black hole growth is influenced by the galaxy
Career:  Survival of the Privileged:  Exploring the Conditions that Allow Supermassive Black Holes and Minority Physicists to Thrive
Title : The Observations of Redshift Evolution in Large Scale Environments (ORELSE) Survey  This program centers on the Observations of Redshift Evolution in Large Scale Environments (ORELSE) survey, a systematic search for structure on scales
The Observations of Redshift Evolution in Large Scale Environments (ORELSE) Survey
RUI: Preparing for the era of the cosmic microwave background polarimetry.  The investigations funded by this award will address several timely questions about the analysis and interpretation of observations of the cosmic microwave background (
RUI: Preparing for the era of cosmic microwave background polarimetry.
Neptune?s atmosphere is one of the most dynamically active atmospheres in our solar system, and yet it is (still) poorly constrained. In order to gain a better understanding of the global circulation in this atmosphere, new sets of observations
The award will be used to fund the research on recently discovered very high energy gamma-ray sources. Working together, UF and Penn Sate teams will carry out a systematic multiwavelength analysis of all available archival data to determine the
Collaborative research: Unidentified Galactic TeV Sources: Neutron Star Connection
We propose to further investigate the formation and evolution of asteroids, comets, and planetary bodies in young exo-systems, by comparing astrophysical mid-infrared observations of dust in exo-solar circumstellar disks to planetary astronomy
Infrared Studies of Circumstellar Dust in Planet-Forming Exo-Systems
Dr. Di Stefano and her co-investigators will use gravitational lensing to explore the local neighborhood of the Galaxy, the region within 1 kiloparsec.and will develop methods to identify local neuron stars, to measure their masses and transver
Mesolensing: Employing the Power of Lensing in the Solar Neighborhood
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  Dr Charlton and her collaborators will conduct a multi-wavelength survey of twelve nearby Hickson compact groups of galaxies. Space-based infrare
Exploring Compact Groups as a Laboratory for Morphological Transformation
'This award will be used to augment the project team with key staff to complete the design efforts, prepare for construction start, support recommended risk reductions and assist in vendor contracting preparation in support of the construction
Funding  Augmentation for the design and development phase of the advanced technology solar telescope
Infrastructure Improvements at the National Optical Astronomy Observatory (NOAO):   NOAO, a Federally Funded Research and Development Center under a Cooperative Agreement with the National Science Foundation, is charged with the oversight and m
Infrastructure Improvements at the National Optical Astronomy Observatory
This project will use the opportunity afforded by the PRE-Depression Investigation of Cloud-systems in the Tropics (PREDICT) field experiment, currently planned for August and September 2010, to investigate the pre-genesis and genesis of North
ARRA Funded:  North Atlantic Tropical Cyclone Genesis Pathways
Research over the past few decades has established that much and perhaps most of the interannual to interdecadal variation of tropical cyclone activity integrated over ocean basins is controlled by the large-scale atmospheric and oceanic enviro
COLLABORATIVE RESEARCH: ENVIRONMENTAL CONTROL OF TROPICAL CYCLONE ACTIVITY
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  Low-frequency atmospheric variability, with time scales from one week to a few months, will be studied by identifying a small number of flow stat
Collaborative Research: Study of the Relationship between Regionally Localized and Zonally Symmetric Anomalously Persistent Weather States
ARRA:  Collaborative Research:  Intermittent and Steady State Processes in Orographic Precipitation
This project aims to conduct a comprehensive investigation of meteoric smoke particles in the polar mesosphere using D-region observations from the Poker Flat incoherent scatter radar (PFISR) in Alaska as well as extensive measurements previous
CEDAR Postdoc: Meteoric Smoke Studies at High Latitude using the Poker Flat ISR
The increased concentration of greenhouse gases in the upper atmosphere is associated with global warming in lower troposphere. It has been suggested that the increasing amounts of these radiatively active gases would lead to global cooling in
ARRA: SPATIO-TEMPORAL STATISTICAL FRAMEWORK FOR THE EVALUATION OF GLOBAL CHANGE IN THE IONOSPHERE
'The project will combine field and modeling investigations to address how the physico-chemical properties of long range transported African dust (LRTAD) aerosol influence Caribbean cloud properties and precipitation levels in a unique Puerto R
Impact of African Dust on Clouds and Precipitation in a Caribbean Tropical Mountain Cloud Forest
ADA  Improvements to Bristol Ferry Road from West Main Rd to Boyd's Lane
ADA Downtown Providence Streets, Washington, Weybosset and Westminster Streets C-2
The Maricopa Small Business Training Program will provide for the deployment of training sessions, a spring series and a fall series, that make up a comprehensive program for entrepreneurial growth. The program will include a curriculum to help
Rural Business Enterprise Grant- Maricopa Small Business Training Program
Conduct moderization activities at various Public Houing developments (All of AMP 1 and a portion of AMP 2).  This funding can be expected to resulting in providing employment for individuals working in heating and cooling industry as installer
Formula Capital Fund Stimulas Grant.  Improvements to Low Rent Public Housing.
Conduct modernization activities at various Public Hoising developments.  This funding can be expected to result in providing employment for architects and engineers. In addition this funding can be expected to substantially modernize public ho
545 - (Combo Loan & Grant) Waste Disposal Only - 09/10 Stimulus
Federal project B082008 involving contract patching and miscellaneous work at various locations  in Transportation District 2 in Johnson and Platte counties.
HPRP funds have been made available under the Title XII of the American Recovery and Reinvestment Act of 2009 with the purpose of providing financial assistance and services to either prevent individuals and families from becoming homeless or h
City of Norfolk Homeless Prevention & Rapid Re-housing Program
Downtown sidewalk accessibility improvements to remove obstacles from existing sidewalks.  The project includes removing existing curbs, installing ramps, installing small segments of sidewalks, installing handrails, and striping street crossin
Federal project B091005, involving crack sealing and miscellaneous work on 85.15 miles on various  roads in Transportation District 1, in Albany, Carbon, Laramie and Sweetwater counties.
The Community Development Blocak Grant Recovery (CDBG-R) program budget includes $140,113.75 for state administration, $6,909,322.25 in Community Development Block Grant - Recovery Funded (CDBG-R) for construction and local administration. The
Public Facilities Improvements  - CDBG/States program and Non-Entitlement Grants in Hawaii (Recovery Act Funded)
AL Dept of Economic and Community Affairs, CED Programs
Communtiy Development Activities:  Public infrastructure improvements for five Idaho communities. The five projects are: City of Dubois - water system improvements to include construction of storage tank, replacement of water lines, booster pum
Idaho Community Development Block Grant - Recovery Program
HOUSING AND COMMUNITY DEVELOPMENT, MASSACHUSETTS DEPT OF
Community Development Block Grant (CDBG-R) funds for infrastructure improvements and public housing modernization awarded to non-entitlement communities.
Community Development Block Grant - ARRA
This award came from the Department of Housing and Urban Development in the form of a Commmunity Development Block Grant to the state of Michigan to be distributed to non-entitlement communities in Michigan.  It is expected that this award will
The Montana Distressed Wood Product Industry Recovery and Stabilization Program (WPIRS) is a federally and state-funded, statewide loan program designed to help businesses in the wood products industry retain or create jobs.  The program was es
Wood Products Industry Recovery and Stabilization  /  Judith Basin County Emergency Services Facility
ECONOMIC AND COMMUNITY DEVELOPMENT, TENNESSEE DEPARTMENT OF
To enable non-entitlement local governments to undertake a wide range of activities intended to create suitable living environments, provide decent affordable housing and create economic opportunities, primarily for persons of low and moderate
Community Development Block Grant Recovery Funds
Community Development Block Grant-Recivery funds for  CDBG Entitlement communities.
CDBG-R funds will be used to consturct a Drainage Project along 16th Ave.
Community Development Block Grant Recovery (CDBG-R)
The award will be used to invest in public facilities and infrastructure improvement projects to help stimulate the economy, create jobs, increase energy efficiency, and expand educational and job training opportunities for low income residents
Community Development Block Grant Recovery
ENTITLEMENT CITY  I ASSUMED THE AWARD DATE WAS THE DATE PER THE FUNDING APPROVAL/ AGREEMENT WHICH WAS THE DATE USE OF FUNDS MAY BEGIN IS 6/04/2009 however the obligation date in IDIS is 9/24/2009.
BARBER ST FROM SCHUMANN DR TO COUNTY RD 512
BAKER ROAD FROM 600 FT. EAST OF US-1 TO SAVANNAH ROAD
CR 315 FROM: SLEEPY HOLLOW DRIVE TO: INTERLACHEN LIBRARY
NE 25TH AVE FROM NE 24TH ST TO NE 34TH PL
TROUTMAN BLVD FROM PORT MALABAR TO PALM BAY RD
CR 466A (MILLER ST) FROM CUTOFF RD TO US 27/441
OCEAN BEACH BLVD FROM WAKULLA LANE TO YOUNG AVENUE
ST. JOHNS AVENUE FROM: SR 19 TO: PALM AVENUE
RINEHART ROAD FROM CR 46A TO LAKE MARY BLVD
NW/NE 111 STREET FROM NW 2 AVENUE TO NE 2 AVENUE
NW 67 AVE/LUDLAM RD AT NW 38 TERRACE AND AT NW 40 STREET
S.W. 80 STREET FROM S.W. 57 AVENUE TO S.W. 47 AVENUE
FRANJO ROAD FROM SW 184 STREET TO OLD CUTLER ROAD
S.W. 127 AVENUE FROM CORAL WAY TO S.W. 8 STREET
MIAMI-DADE CO COMMSN DISTRICT 4 - ADA BUS STOP ACCESS(VARIOUS LOCATIONS)
SW 320 STREET FROM SW 192 AVENUE TO SW 177 AVENUE`1
SUNSET DRIVE BRIDGE #876708  FROM 22 STREET TO 23 STREET
CROSS SEMINOLE TRAIL OVER HOWELL CREEK MULTI-USE TRAIL
TWELFTH STREET FROM FLAGLER AVENUE    TO K-MART/PATTERSON ST.(ADA)
EISENHOWER DRIVE FROM PALM AVENUE TO TRUMAN AVENUE    (ADA)
N.W. 95 STREET FROM N.W. 36 AVENUE TO N.W. 33 AVENUE
LEHMAN CSWY PATH FROM W. COUNTRY CLUB DR. TO E. COUNTRY CLUB DR.
S.W. 72ND STREET FROM S.W. 157 AVENUE TO S.W. 127 AVENUE
S.W. 82 AVENUE FROM S.W. 40 ST/BIRD ROAD TO S.W. 8 STREET
SW 212 STREET FROM SW 122 AVENUE TO SW 119 AVENUE
SW 56 STREET FROM SW 162 AVENUE TO SW 157 AVENUE
SR 77 PHASE 1 SIDEWALK-CITY OF CHIPLEY 2009 ECONOMIC STIMULUS
CR 953 (BALD EAGLE) FROM CR 92 (SAN MARCO RD) TO ELKCAM CIRCLE
M.L.K JR. STREET FROM BOOKER T WASHINGTON TO US 17/SR 35
85TH STREET FROM GULF DRIVE TO MARINA DRIVE
SR 789 LONGBOAT KEY FROM N OF NEW PASS BRIDGE TO MANATEE C/L
HOLMES BOULEVARD FROM 54TH STREET TO 66TH STREET
CR 453 W STREET FROM NORTH SR 95 (US 29) TO FAIRFIELD DRIVE
CR 30A FROM SR 30E CAPE SAN BLAS ROAD TO APPROX. 0.3 MILE EAST
SR 79 FIRST AVENUE SIDEWALKS 2009 ECONOMIC STIMULUS
IDLEWILD DRIVE FROM SR 20 APALACHEE PKWY TO PROCK DR/PICCADILLY CI
CR 30A BIG REDFISH LAKE PEDESTRIAN BRIDGE
STATE PARK RD SR 77 FALLING WATERS ENTRANCE
WASHINGTON COUNTY PAVEMENT MARKINGS 2009 ECONOMIC STIMULUS
PINE AVENUE FROM GULF DRIVE TO BAY BOULEVARD
CR 832 (KERI ROAD) FROM SR 29 TO 9.0 MILES E OF SR 29
HOME AVE FROM SEBRING PKWY TO SR 17 (NORTHGATE DR)
S.W. 109 AVENUE FROM S.W. 8 STREET TO WEST FLAGLER STREET
S.W. 114 AVENUE FROM S.W. 7 TERRACE TO WEST FLAGLER STREET
To purchase capital items for a business incubator/training facility necessary for small winemaking enterprises to enter the market. As of 10/01/10, all equipment for this project has been ordered and delivery is expected before the end of Octo
Southern Oregon Wine Institute: The wine incubator
Bridge Deck Replacement Program Main St (CR 543) over Rt 206, Construction
Highway Infrastructure Investment - Bridge replacement, added capacity (added travel lanes) - From funding for use in any Area (flexible)
Interstate 480 Southbound / US-75 over 30th St. Exit, Omaha
Interstate 480 Westbound Bridge over 24th St., Omaha
Evaluation panel member tasked with reviewing applications received in response to a solicitation for grant applications (SGA).
evaluation panel member tasked with reviewing applications received in response to a solicitation for grant applications (SGA). Grants awarded as a result of the SGA will be related to ARRA initiatives and are funded with ARRA funding
Minot - 31st St SE from Burdick Expressway to 11th Ave SE
Minot - 21st Ave NW from US 83 Bypass to 20th St NW
American Recovery and Reinvestment Act funds enabled Connecticut's two food banks, Foodshare, Inc. and Connecticut Food Bank, Inc. to pay costs associated with the distribution of USDA foods donated for use in The Emergency Food Assistance Prog
CITY OF ROCHESTER'S PAVEMENT MAINTENANCE PROJECT
RIDGE ROAD SIDEWALK REPLACEMENT (HAMLET OF WILLIAMSON)
Safety and Resurfacing MD 201 to Riverdale Road
Rehabilitate 24 Road Segments in Stockton.
FAU 8609, BROOKSIDE AVE FROM 15TH ST TO 17TH ST IN WAMAC
Bridge and roads Widening from 5 to 8 lanes,  upgrade traffic signals, & RR improvements
Portola Ave,East Ave, E. Stanley Blvd., and Murrieta Blvd.
Traffic Related - Purchase and Installation of GPS Emergency Vehicle Traffic signal Preemption (EVP)
GATEWAY BLVD. FROM TRAVIS BD TO PENNSYLVANIA , PAVEMENT REHABILITATION
Install E/B & W/B dual left-turn lanes within existing RW, and minor ITS elements
SIDEWALKS REMOVAL, REPLACEMENT & PED. RAMPS
Capitol Boulevard Sidewalk and Bike Lane Project
Asphalt Concrete Overlay, Curb & gutter, Minor local repair
Road rehabilitation and replace curb, gutter, and sidewalk
Asphalt Concrete Overlay  and other improvements
Raised landscape Island, other improvement
LED Internally Illuminated Street Name Sign Replacement
CMC 5351 - FROM From 4 Miles South of US 2, N
Campus Drive Rehab; Reconstruct Pavement, construct ADA ramps, driveways, and curb & Gutters
The City's current sweeper is 24-yrs old, unreliable, and requires 3 hrs. of maintenance for 5 hours of operation. Current capital and operating reserves are not sufficient to meet the need to replace both the sweeper and two other trucks that
City of Stevenson Street Sweeper Purchase-to purchase a used street sweeper to replace existing sweeper.
Regulation and Administration of Transportation Programs
Asphalt Concrete Overlay and Microsurfacing (seal coat)
MINNESOTA STATE COMMUNITY TECHNICAL COLLEGE
Hiring of business entrepreneur center staff and start up equipment for the business incubator.
Minnesota State Community and Technical College Business and Entrepreneurial Services, business incubator program
3 ARRA PROJECTS; MAIN ST & ONTARIO ST & 11TH ST RESURFACING
4 ARRA PROJECTS;PACKARD&LINDBERGH&HIGHLAND&56TH ST RESURFACE
NASH RD RESURFACE;CHERRY HILL-STEIG RD&ERRICK-LOCKPORT RD
NY RT 430/CR 128 & CR 44/CR 13; BEMUS POINT - ELLERY CENTER
Asphalt Concrete Overlay, center left-turn lane
Upgrade County Highway J-59 - Reconstrution and Repaving
Pavement rehabilitation and intersection improvements
Ped and vehicle circulation improvements including sidewalks, curb ramps, parking improvements, etc.
Dickinson - 21st Street W from 10th Avenue W to 10th Ave E
The Mississippi Department of Human Services (MDHS) received funds through the American Recovery and Reinvestment Act of 2009(ARRA) to pay cost associated with the distribution of USDA foods purchased for use in The Emergency Food Assistance Pr
Mississippi Department of Human Services, CAP Recovery Act - TEFAP Administrative Funds
NORTH CAROLINA DEPARTMENT OF AGRICULTURE & CONSUMER SERVICES
ARRA administrative financial assistance has been made available to six of the State's food banks for the storing, handling and delivering of USDA donated food commodities.  Funding has provided nutritious food to an increased number of senior
USDA ARRA funds provided on a competitive basis to LEAs/SFAs to purchase equipment.
MOF-CRACK SEALING;VARIOUS ROUTES; CHAUT COUNTY; SFY 09/10
MOF-CRACK SEALING;VARIOUS ROUTES;NIAGARA COUNTY;SFY 09/10
This grant award is providing the Community Health Center with an Electronic Health Record and Patient management System.  The CCCHC is also upgrading much of the clinical equipment so that vital signs and diagnostic test results can be recorde
ASIAN HUMAN SERVICES FAMILY HEALTH CENTER
Asian Human Services Family Health Center (AHSFHC) will increase its efficiency and ability to serve its community through an approach using two projects:  renovation project with equipment/IT - build out of a shell area in the current facility
This grant enables Project Renewal to upgrade all components of E Clinical Works (EHR) network infrastructure. New healthcare information technology equipment will significantly increase uptime and availability at our shelter based clinics, inc
San Diego Family Care was awarded CIP funds for the purpose of purchasing/implementing a Certified EHR-related system and also for the purpose of purchasing IT Equipment. The funds enabled the conversion of paper medical records to electronic m
MOUNTAIN COMPREHENSIVE HEALTH CORP., INC.
MCHC operates in an area with considerably higher rates of health disparities than both state and national averages. The communities served by MCHC report rates of poverty more than double and unemployment significantly higher than comparable n
to improve the health status of homeless persons in the New Orleans area by providing a holistic multi-disciplinary team appoach to problems facing homeless individuals and their families.
ARRA-Health Center Integrated Services Development
Wasatch Homeless Health Care, Inc.'s CIP grant covers $290,050 in Renovation/Repair expenses and $160,000 in Electronic Health Record (EHR) conversion expenses. The renovation and repair project aims to create better internal efficiencies by pr
ARRA - Capital Improvement Program funds will address our community's immediate needs in several ways:  1)  a new facility is needed to replace the old Bogard Center which is severely undersized for its purpose, and has both structural and drai
MOREHOUSE COMMUNITY MEDICAL CENTERS, INC.
The purpose of this award is to increase access to primary health care by expanding the number of exam rooms available at the clinic, relocating the administrative offices, and renovating a school based health center. The project includes using
Katy Trail Community Health Capital Improvement Program grant to resurface our parking lot, install four dental chairs and to support Information Technology infrastructure. All three project are complete and we have hired 5 full time staff.
ARRA - Capital Improvement Program  The original YVFWC CIP described 5 projects: 1) Toppenish Clinic Call Center & Front Office Remodel (A/R/R)project, 2) Mountainview Interior Upgrade (A/R/R) project, 3) Dental Automation (HIT-only) project, 4
Mobile Dental Van.   Capital Improvement Program (CIP)funds will be used by San Mateo Medical Center (SMMC) for the purchase of a 4 chair, wheelchair accessible mobile dental clinic.  This will provide SMMC with the capacity to increase service
Agency for Toxic Substances and Disease Registry
PHS will use IDS dollars strategically in the next two years to 1) maintain its capacity to provide a comprehensive primary care home to an increasing number of people in need of its services, and 2) retain jobs.  The IDS funding will allow us
The IDS award funding was to hire patient care staff to address the ever growing need for health services among our target population in Lincoln, Nebraska.  New patients to the Health Center were waiting 14-16 weeks for an appointment and estab
MANATEE COUNTY RURAL HEALTH SERVICES, INC.
Manatee County Rural Health Services, Inc. (MCRHS) will address increased access and increased capacity for individuals and families utilizing the following strategies and methods.  The IDS project will result in an additional 13.4 new FTE or 1
AMMONOOSUC COMMUNITY HEALTH SERVICES INC
ARRA - Increased Demand for Services.  The purpose of this grant is to meet the increasing need for services from new patients and uninsured patients.  We expect to add 600 new patients and 100 new uninsured patients over the project period.  T
ARRA IDS Increase Service for the Health Center.These funds will enable EBCAP to hire a Quality Improvement Coordinator to oversee the ongoing evaluation of quality improvement plans that include performance measurement of health outcomes again
HRSA-ARRA-Increase Services to Health Centers.  The goal of the grant is to provide increased primary health services to low-income individuals in southern Ohio.  It is expected that services will be provided to 1,000 new health center patients
ARRA Grant ? Increased Services to Health Care Centers to support staff positions in order to allow vitally needed uninsured and poverty level adult and children patient access to (1) mental health counseling and medication therapy management,
ARRA - Increased Services to Health Care Centers
NEIGHBORHOOD HEALTH ASSOCIATION OF TOLEDO, INC.
ARRA - Increased Services to Community Health Centers
REGENESIS ORGANIZATION COMMUNITY HEALTH CENTER (ROCHC)
ARRA IDS-Immediate Demand for Services to cover new uninusred health care seekers.
Jefferson Comprehensive Health Center, Inc. used grant funds to extend the hours of operation, hire additional staff and retain staff.
Jefferson Comprehensive Health Center, Inc.
Increased Demand for Services. Off hours medical and dental clinics.
Central City Concern (CCC) will add capacity for medical services at the Old Town Clinic and at the 12th Ave Recovery Center, which is a Community Mental Health Center, and retain medical capacity that would have been lost at  Hooper Urgent Car
The IDS project will help Pueblo Community Health Center remove people from our waiting list and enroll more people into PCHC while creating health care homes for those in need. When people do not have health care coverage and/or access to care
ARRA - Increase Services to Health Centers; Increased Demand for Services (IDS)
The name of the award is Increase Demand for Services (IDS. It is part of the ARRA funding. The goal of the ARRA funding was to assist health centers in employing sufficient staff to support on going operations in light of increased numbers of
Grant Name: Increased Demand for Services (IDS) Purpose: IDS funds were awarded by Health resources and Services Administration (HRSA) to address the primary health care needs of Asian Human Services Family Health Center (AHSFHC) growing uninsu
Asian Human Services Family Health Center
US 2 - From Michigan Bypass E To County Line
This grant was awarded to Maniilaq Association for a one time purchase and implementation of telepharmacy for Selawik Clinic
Work consists of design, fabircation and installaion of reconditioned flatbed railcar bridge including, cast-in place or pre-cast fabricated abutments
Remove & Replace asphalt entrance roads DC Booth National Historic Fish Hatchery Lawerence County South Dakota
Electrical work at the Sand Lake NWR, 39650 Sand Lake Drive, Columbia, SD
Replacement of (3) 100K unit heaters with 83% efficient heaters.
ND 66 - From S Jct 81-St. Thomas E TO I-29
ND 66 - From S JCT 32-Gardar E To Crystal
The Hematology Coagulation Analyzer is a piece of equipment used for monitoring coumadin therapy or blood clotting in patients.  For fiscal year 2009, the Chicksaw Nation Health System did 3,703 of these tests using this piece of equipment.  Ou
Hematology Coagulation Analyzer and Glidescope Video Larynscope Equipment
Loan awarded for the construction of potable water infrastructure in the rural community of Yahuecas in the municipality of Adjuntas.
(RD 131) Improvements to the Yahuecas Aqueduct System Phase II
SOIL AND WATER CONSERVATION COMMISSION, GEORGIA
The Georgia Soil & Water Conservation Commission has received Recovery Act funding from United States Department of Agriculture to implement REHAB Program to perform modifications on five Watershed Flood Control structures in three counties in
Georgia Soil & Water Conservation Commission Rehabilitation of Five NRCS Watershed Dams
WASHINGTON AVENUE ELMIRA HIGHWAY RECONSTRUCTION
CUBA LANDMARK CONNECTION - GVG ENHANCEMENT
rehabilitation construction of Sugar Creek Site L44 in Caddo County Oklahoma
remedial construciton of Uncle John Creek Site 5 seep in Canadian County Oklahoma and Bear Fall Coon Creek Site 6 seep in Logan County Oklahoma. Award amount decreased July 2010 due to lower bids.
Uncle John 5 seep and Bear Fall Coon 6 seep
The purpose of this task order is for the Ruston/North Tacoma Study Area project. The period of performance for this work is 09/22/2009 to 06/30/2010. This work is to prepare a remedial design (RD) for the completion of residential yard remedia
Mitigation area preparation and planting of trees, irrigation of trees, shredding mitigation area.
Grand Forks - University Avenue from 3rd Street N to State Street
Grand Forks - 8th Avenue N from 3rd Street N to Columbia Road
HOUSING AUTHORITY OF THE CITY OF DALLAS GA INC, THE
replace vinyl siding, fascia, and re-roofing in GA-148-4, also re-roofing in GA-148-5. We expect to hire unemployed workers.
This proposal will enable Camillus Health Concern (CHC) to upgrade its information technology and facility capacities. Upgrading its EHR to Sage Intergy, a certified EHR system, will maximize workflow efficiencies and enhance CHC's ability to i
The Capital Improvement Program grant allows funding for projects that feature construction and alteration/repair/renovation, IT/Equipment only, health information technology, and overall electronic health record projects.  The $443,375 award w
ARRA - Capital Improvement Grant covers three projects: 1. renovation of our Alto dental clinic into medical exam rooms; 2. renovation of our Southside dental clinic into medical exam rooms; 3. renovation of the Alto and Southside clinic locati
The purpose of this grant is to improve the access to primary care madical services to an estimated 3,644 individuals in Washington and Yamhill Counties, Oregon.
The Texas Department of Agriculture received funds through the American Recovery and Reimvestment Act of 2009 (ARRA) to assist in the purchase of equipment for School Food Authorities (SFA's) participating in the National School Lunch Program (
To imporve migratory fish passage on Wasilla Creek at Grantham Road by building a bridge to replace an undersized culvert.
Fish Passage Restoration on Wasilla Creek at Grantham Road (Barrier CC047), AK
Restore fish passage for coho salmon, pink salmon, and cutthroat trout to improve rearing and spawning habitat in Eccles Creek and tributary Whiskey Creek. This will be accomplished by replacing two culverts associated with Whiskey Creek and on
Funds the Division of Agriculture, Plant Materials Center to eradicate and evaluate efforts to eradicate spotted knapweed from the state of Alaska.  Spotted knapweed is a notorious invasive weed that costs millions of dollars in management and
Eradication of spotted knapweed from known locations in Alaska
The purpose of this grant was to manage small incipient infestations of invasive weeds across Alaska.  Targeting small infestations of weeds, before they grow out of control, is known as early detection and rapid-response.  EDRR is the most cos
Early detection and rapid response to eradicate invasive plants across Alaska
Rt 35 Restoration Toms River Twp to Mantoloking, Design
a grant to allow the extension of the sewer service area to serve existing homes with failing septic systems and to allow access for undeveloped lots in a subdivision.  Also, will upgrade the existing pump station and generator.
Quaker Neck/Lover's Lane/Prestwick Wastewater Collection System Extension
Funding to continue Highway Enforcement Apprhension Team.
Purchase of public safety equipment for law enforcement.
Combined Law Enforcement Technology Program
Computer and Computer Peripheral Equipment and Software Merchant Wholesalers
DOJ grant to purchase 2 patrol vehicles and equipment.
The overall purpose for this program is to create a position within our Agency that will work full-time on criminal and gang investigations with an emphasis on breaking the Spanish language and cultural barriers. This person will have expertise
Purchase of radar units,police vehicles adn related equipment
Purchase of radar units and police vehicles.
The City of Boone Police Department was awarded $28,313 thru the Byrne Jag Grant. The monies will be used for training law enforcement officers. The purpose of this training is to better prepare our new/current Police Officers to handle emergen
The Redmond Police Department will utilize the Federal Fiscal year (FYY) 2009 Edward Byrne Memorial Justice Assistance Grant (JAG) to fund the following four areas;  1-Focused enforcement areas for the Truancy Prevention Program, city parks, do
Technology Improvement:Goal-To provide all municipalities along with the District Attorney, the school district and other county and state agencies the ability to view our case management system in order to have real-time information on probati
Greenville County government is seeking a grant for law enforcement and judicial supposrt programs with the objective of enhancing and continuing programs established  in the County?s public safety, law enforcement and judicial departments.  Fu
Public Safety and Judicial Enhancement Programs
This award aids the Mount Vernon Police Department by providing supplementary part-time assistance, training and minor equipment related to crime prevention.
2009 Mount Vernon Police Department Edward Byrne Memorial Justice Assistance Grant
BJA - Byrne JAG - Technology Improvement
The award will reduce costs by eliminating unnecessary court appearances and discouraging frivolous or unfounded law suits by recording and preserving evidence to refute unfounded claims.  There will also be reduced costs by decreasing injuries
Marshall Police Department 2009 Edward Byrne Local Project
Update PD's outdated in-car video system
Digital in-car video system for patrol vehicles
The Justice Assistance Grant (JAG) Program funded under the Recovery Act provides federal criminal justice funding to local jurisdictions.  These funds support all components of the criminal justice system.  Recovery JAG funded projects may add
Justice Assistance Recovery Local Solicitation Award. This funding has allowed the City of Jackson to fund ten (10) officer positions that otherwise would have been eliminated. The primary goal of the COPS Officer positions was to allow the pol
To provide overtime and equipment to enhance law enforcement efforts in Richland County, South Carolina.
The goal of this proposal is to provide law enforcement agencies within this region with the required resources to promote and support strategies to reduce crime.  The following strategies will ensure success of the grant: (a) A member from eac
2009 Regional Wake County JAG Grant (BJA FY 09 Recovery Act Edward Byrne Memorial Justice Assistance Grant)
Evansville Community Police Partnership Progam.  Funds will provide necessary equipment for six new officers.  The funding will also be used to purchase equipment to be used in a firing range that will be used by multiple agenices in Southweste
FY 2009 RECOVERY ACT JUSTICE ASSISTANCE GRANT PROGRAM
To purchase lap top computers for road deputies vehicles. Replace old radar units. Purchase a prisoner holding cell for safety.
Westfield City Recovery Act Justice Assistance Grant Program
The Campbellsville Police Criminal Invesigations Enhancement Program will allow us to aquire equipement to enhance the ability to increase the number of latent prints collected and the ability to increase arrest. The implementation stratedy is
Campbellsville Police Department Criminal Investigations Enhancement Program, to purchase forensic evidence equipment.
The Edward Byrne Memorial Justice Assistance Grant (JAG) Program is the primary provider of federal criminal justice funding to state and local jurisdictions.  JAG funds support all components of the criminal justice system.  JAG funded project
Edward Byrne Memorial Justice Assistance Grant (JAG)
The objective of this grant funding is to retain a position in the Chatham County Sheriff's Office that will be dropped without grant funding.  Funding will allow the continuation of a Criminal Enforcement/K9 Team Field Supervisor, who will con
This grant was to fund an in-car computer system. All equipment has been received, installed, and is now operational. Close out will begin soon.
To purchase equipment for the Hanford POlice Department.
to purchase quipment for the Hanford POlice Department
FY'09 Recovery Act Justice Assistance Grant Program Local Solicitation to promote economic recovery by assisting local law enforcement agencies in improving the effectiveness and efficiency of criminal justice systems, processes, and procedures
FY'2009 Recovery Act Edward Byrne Memorial JAG Program Local Solicitation
Rockingham Co. will use its FY 2009 Recovery Act JAG funds for the following 3 purposes:  1) to reduce & ultimately prevent incident of youth crime & violence & youth gang involvement in each school in Rockingham Co. by creating a proactive app
2009 Rockingham County Specialized Equipment Grant
Lawrence Police Department Interoperable Communications Improvement and Crime Prevention and Control Grant
The goal of the Baltimore County Police Department's Recovery Act Formula Grant program is to serve and protect the citizens of Baltimore County, Maryland through enhancement of its law enforcement services.  The Department will hire and train
The North Slope Borough will use funds to purchase emergency 911 equipment; off road police patrol vehicles; and satellite telephones for officers in each of seven remote village.
Purchase a radio console to upgrade dispatch
The purchase of an American-made full-size sport utility police patrol vehicle will create and preserve American jobs.  Said vehicle will also enhance the performance of the police patrol fleet.  This vehicle will allow for police officers to b
JAG Recovery Act Police Vehicle Purchase
This grant utilized funds to purchase another police vehicle that is was not budgeted for this year. The condition of our police vehicles are very poor to say the least and this additional vehicle will assist us in combating crime by giving us
Walker County Law Enforcement Technology and Safety Upgrades
The Town of Florence was awarded funds to assist the Florence Police Department with the cost of providing basic clothing and equipment for two new police officers, plus providing necessary add-ons to two new police patrol vehicles.
Hiring and retaining personnel, and acquiring equipment and technology in Tulare County. Seven jobs will be preserved and one will be created: Animal Control Officer, School Resource Officer, Elder Abuse Investigator, Witness Coordinator, Prose
Recovery Act: Edward Byrne, Justice Assistance Grant Program, Tulare County. As a disparate jurisdiction, we submitted a single joint application to address the purposes of the Recovery Act and several JAG Purpose areas.
We accomplished our goal from installing more of the portable video surveillance equipment and we have 24/7 surveillance of the Business District along with the ability to place overt cameras wherever they are needed.
NSB PD Portable Mobile Video Surveillance System
The Paulding County Sheriff's Office plans to update and improve the equipment and technology available to our law enforcement personnel.
Law Enforcement Equipment and Technology Improvements
Purchase of mobile data terminals for police vehicles.
Rehire of career law enforcement officers.
Holyoke Police Department Hiring Program
5 Police Segways, 10 Police Mountain Bikes, 1 Police Motorcycle, 16 E-TIX
The City of Houston and Harris County are listed as disparate jurisdictions under the fiscal agent for this grant.  JAG funds will be used to fund contracted positions, law enforcement equipment, training and information technology upgrades.
The Alameda County Justice Assistance Grant Joint Consortium.
Expansion of Ecite and MOVE in patrol units of the Shelby County Sheriff's Office.  The programs and equipment will enchance the ability of deputies to handle workloads more efficiently.  This will allow other personnel assigned to Federal Task
Purchase two (2) Mobile Vision Flashback Video systems for  police cruisers; upgrade telephone system in the public safety building; and purchase five (5) new Tasers making one available to each active officer.
Van Zandt County Sheriff's Office Technology Improvement Project.  Project will allow for the purchase of digital mobile video/computer hardware and software to improve the abilities of Sheriff's Patrol Deputies to video events and communicate
One year of funding for 50% of wages and fringes for four (4 )School Resource Officer positions that were slated for lay-off due to economic downturn. Two (2) FTE positions will be retained as a result of Recovery Act funding.  The funding for
Upgrading of patrol cameras from obsolete cameras to court required digital cameras
Recovery Act funds (ARRA) to be utilized for crime prevention and  police equipment.
This grant serves three agencies; the Rocky Mount Police Department, the Nashville Police Department, and the Nash County Sheriff?s Department.  The objective of this project is to utilize grant funds for the purchase of equipment and technolog
Equipment and Technology Improvement Project
The Town of North Brookfield will use JAG funds to purchase 2009 Ford Crown Victoria to replace 2006 model that is unreliable and unsafe
Electronic Control Device (Taser) program
This award was received under the Recovery Act Edward Byrne Memorial Justice Assistance Grant (JAG) Formula Program: Local Solicitation and will fund the 2009 Mobile Area Law Enforcement Initiative. The purpose of this award is to purchase upda
2009 Mobile Area Law Enforcement Initiative
The disparate jurisdictions consisting of Kalamazoo County, the cities of Kalamazoo and Portage, and Kalamazoo Charter Township will use their Fiscal Year 2009 Recovery JAG award in the amount of $553,309 to enhance service delivery, increase o
Edward Byrne Memorial Justice Assistance Grant Program, Recovery Act, Kenai Peninsula Borough.  Funds to be utilized by the various recipients to further law enforcement services to the community, improve existing communications and enhance wor
Communications and Computer Systems Stabilization and Improvement Project
Combating Criminal Theft and VICE Operations.
Combating Criminal Theft and Vice Operations
The grant will be used to purchase police equipment and/or technology.
Public Safety System - Wide Upgrade Project
Alexander City, city of Dadeville, and the county of Tallapoosa will share the Recovery Act JAG award. The Alexander City Police Department will serve as the fiscal agent managing the Recovery Act JAG award. AJexander City will purchase equipme
BJA FY 09 Recovery Act Edward Byrne Memorial Justice Assistance Grant Program Local
FY09 Recovery Act Edward Byrne Memorial Justice Assistance Grant Program Local Solicitation - The Kitsap County Sheriff's Office is a 24/7, 365 days a year operation.  With funding for Deputy Sheriff salaries and the purchase, installation, and
Allegany County Combined Equipmwnt Funds
Purchase of long term lease of Automated Fingerprinting Identification System hard and software.
Pelham Police Vehicle Grant:  To monitor and patrol the streets and highways of Pelham, Alabama and to promote the safety and well being of its citizens.
Police cruiser, computerized voice stress analyzer aquisiton program.
Police cruiser and voice stress analyzer aquisiton program
FY 2009 Recovery Act Justice Assistance Grant Program. The Justice Assistance Grant Program funded under the Recovery Act is the primary provider of federal criminal justice funding to state and local jurisdictions.  Recovery JAG funds support
The City of Acworth will apply Recovery Act JAG Funds towards essential equipment for its police department's traffic safety unit.  The unit is responsible for educating the public on issues relating to traffic safety, enforcing traffic laws, a
Recovery Act JAG provides IT equipment, consulting services, and law enforcement equipment.
The City of Chelsea, through the Chelsea Police Department (CPD), will utilize its Fiscal Year 2009 Recovery Act JAG award to support the Chelsea Police.  The goals are to retain two part-time positions, fund overtime for the gang, drug, and an
El Paso de Robles will use Recovery Act JAG funds to support technological upgrades for the police department. Funds will be used to purchase Taser units to prevent officer injury, radar units for speed enforcement, and an electronic ticketing
These disparate jurisdictions; City of Casper, Town of Mills, and Natrona County will use their Recovery Act JAG award to support law enforcement, make equipment purchases and improve officer safety.  The City of Casper and the Town of Mills ar
City of Casper2009 Justice Assistance Grant
BJA FY 09 Recovery Act Edward Byrne Memorial Justice Assistance Grant Program Local Solicitation. This grant has been used to pay for Spanish Immersion Training, firearms, online crime reporting, forensic computer equipment, a camera, and AED b
Live Scan Fingerprinting and Nist Archive Equipment.
Edward Byrne Memorial Justice Assistance program
Recovery act:).  The stated purposes of the Recovery Act are; to preserve and create jobs and promote economic recovery; to assist those most impacted by the recession; to provide investments needed to increase economic efficiency by spurring t
This award will be utilized to fund training and equipment purchases to enhance the underwater investigations, recovery, and rescue needs. The Sheriff's Underwater Investigations and Recovery Team will attend training to meet the minimum capabi
Underwater Investigations & Recovery Enhancement Project
BJA FY 09 Recovery Act Edward Byrne Memorial Justice Assistance Grant Program Local Solicitation - Anderson County Sheriff's Office Equipment.  To increase the number of apprehended fleeing suspects and missing or lost persons by 100% during th
Purchased computers, evidence software, printers, radios and scanners to enhance technology within the department. Items purchased replaced old, worn out equipment or provided items not previously owned. The expected outcome is improved perform
Blackman Township Public Safety: Technology Enhancement Grant
2009 South Bend Police Department interdepartmental Justice Assistance Grant (JAG) Application. The goals of the project which are improved officer safety, increased productivity will be accomplished through the purchase of equipment which has
City of South Bend Collaborative equipment initiative
PALMERTON BOROUGH AND MAHONING TOWNSHIP JOINT RECOVERY ACT JAG PROJECT
$37,554.00 has been awarded to the Medford Police Department's Equipment Enhancement Program to purchase 3 items that would assist in making the Medford Police Department a more thorough and efficient police Department. Those items are a Automa
Medford Police Equipment Enhancement Program
JOSEPHINE COUNTY JUVENILE SHELTER & DETENTION CENTER
The purpose of the project is to maintain 1.85 fte to Child Advocacy in Josephine County.  It is expected that the total award will be expended over the three year period to attain this goal.
Josephine County Juvenile Justice Child Advocacy Preservation Program
FY 2009 Recovery Act Justice Assistance Grant Program.  The Disparate Jurisdictions of Eugene City and Lane County will use the award funds to fund a full-time training sergeant, critical training in the areas of EVOC and Defensive Tactics, and
BJA FY 09  Recovery Act Edward Byrne Memorial Justice Assistance Grant Program Local Solicitation
To purchase two dual-purpose police motorcycles that will be used to patrol off-road areas where under-age alcohol consumption, clandestine drug lab operations and marijuana usage are known to exist. Funds will also be used to purchase crime st
BJA FY 09 RECOVERY ACT EDWARD BYRNE MEMORIAL JUSTICE ASSISTANCE GRANT PROGRAM LOCAL SOLICITAION
The Uvalde County Sheriff's Office will utilize its portion of funds to purchase the following items for its officers: mobile radar units, digital cameras, traffic enforcement equipment, less-than-lethal devices, and ammunition.  The city of Uv
DNA.  The new technologies make profiling and identifying local offenders of property crimes and burglary a viable option for law enforcement officials to solve crimes and make arrests.  Creation of a comprehensive local database will assist i
Washington County Sheriff's Office K9 Vehicle.
Washington County Sheriff's Office K9 Vehicle
Justice Assistance Grant for Law Enforcement
The City of Roanoke will use the Recovery Act JAG funds to pay the salary of the part-time information technology specialist (crime analyst) position to identify crime trends/hot spots in the community; purchase expendable and technology equipm
Roanoke Bicycle Patrol, Crime Prevention and Technology Improvement Program
The City of Hampton will use the Recovery Act JAG funds to purchase much needed equipment for the police department.  As technology improved over the past decades, local fiscal constraints limited the police department's abillity to secure equi
Hampton Police Equipment Innovation, Upgrade and Capability Enhancement Project
Recovery Act/BJA-Byrne JAG Jefferson County Sheriff SAR Program Creation
Jefferson County Sheriff's Office SAR Program Creation
Equipment award directed toward budget reduction.
Pageland Police Departments Equipment Directed Budget Reduction Program
Operation Equipment for Enhanced Patrol Activities
Automobile and Other Motor Vehicle Merchant Wholesalers
Blacksburg Police are using the grant funding to purchase fourteen Panasonic laptop computers to be installed into patrol vehicles for use by officers to perform daily police functions in a timely manner and without delay of service to the comm
Purchase six police cruisers with ancillary equipment
Purchase of Six Police Cruisers with Ancillary Equipment
The goal of our program is to improve efficiency and effectiveness of current police operations in an effort to reduce crime, specifically, violent crime.  We plan to enhance our technological abilities for Patrol, Investigation, Crime Analysis
Automatic License Plate Recognition System
Equipment/Technology for the Conyers Police Department - In-Car Video Camera Systems and Mobile Voice System
Equipment/Technology for the Conyers Police Department
Flagler County Law Enforcement Equipment Grant
City of Midland - Acquisition of equipment and technology  Midland County - Tactical team support and training
City of Midland - FY2009 JAG Equipment and Technology Acquisition/Midland County - Tactical Team Support and Training
Revised Award Description (Grant Adjustment Notice for revision approved 6/7/10):         The objectives for the use of the JAG funds are:  1. Augment Neighborhood Patrols: Field additional police officers on select weekend nights to focus on n
Funding for overtime to augment neighborhood and downtown police patrols and records processing.
Memorandum of  Understanding w between the Paducah Police and McCracken County Sheriff Departments to purchase 12-AR-15 replacement  weapons; 26-pocket printers;10-scanners, and 50-tasers for  patrol division. Smaller  equipment  items  such as
Our department plans to spend $16,784 for a new dispatch console for our communications area.  The plan for the remainder of the money is to purchase digital recording systems for our patrol units.
Goal of award is to provide in car computers for the Hereford Police Department and Deaf Smith County Sheriff's Office.  Grant monies have been partially expended.
The City of Norcross will use Recovery Act JAG funds in the amount of $70,993 to purchase law enforcement equipment that will improve the efficiency and effectiveness of its police department.  Specifically, grant funds will be used to purchase
BJA FY09 Recovery Act Edward Byrne Memorial Justice Grant Program Local Solicitation. The City of Virginia Beach will use its Fiscal Year 2009 Recovery JAG Act award to enhance law enforcement, courts, corrections, and drug programs. The Virgin
BJA FY09 Recovery Act Edward Byrne Memorial Justice Grant Program Local Solicitation
The Tri-City Tactical Team TEMS and Equipment program is a two-part program.  The first element will fund two tactical paramedics to work with the Tri-City Tactical Team (TCTT).  The funds will be used to pay salaries and benefits for the param
Equipment and training costs for five area law enforcement agencies.  The goals of the project will be to improve the capabilities of agencies in order to better serve the communities, while preserving and creating jobs through carfeul and cons
Creating a dispatch position in Mower County
Newaygo County's 2009 ARRA Justice Assistance Grant Award was used to purchase 10 toughbook laptops for road patrol vehicles.  This enables officers to run information on suspects without needing to call Central Dispatch.  It also brings the Co
Newaygo County Sheriff's Office Technology Improvement Program
Grant monies will aid in the funding of the Ypsilanti Police Department's Technology Reinvestment Initiative. This initiative will aid in the replacement of ailing technology which will help to enhance community based programs.
BJA FY 09 Recovery Act funds to be utilized for the purchase an Automated License Plate Reader to be installed in a patrol vehicle.
Reducing crime through the recovery of stolen vehicles and tracking of known offenders' travel.
Corinth/Alcorn County Law Enforcement Training Center
The Indian River County Sheriff's Office proposes to utilize $100,076.00 of the $132,883.00 allocation to the County to purchase much needed equipment for the agency. The Substance Abuse Council proposes to utilized the remaining $32,807 for dr
FY 2009 RECOVERY ACT JAG PROGRAM -- DINWIDDIE COUNTY THROUGH ITS SHERIFF'S OFFICE WILL USE THIS AWARD TO PURCHASE TRAFFIC RADAR AND SURVEILLANCE EQUIPMENT TO BE USED TO SUPPORT LAW ENFORCEMENT INVESTIGATIONS AND TRAFFIC MONITORING INCIDENTS.
Communications infrastructure upgrade to meet FCC narrow banding requirements.
The City of Jacksonville Beach is an eight and one-half square mile, incorporated city within Duval County, Florida.  The city has 21,500 full-time residents and the county has approximately to 750,000 residents.  The city has over 2,500 busine
Jacksonville Beach Police Department Radio Equipment Upgrade
Superior Police Night Protection Project: 1. Purchase and deploy ANSI certified reflective vests for officers. 2. Purchase and deploy rechargeable flashlights for Superior Police Officers 3. Purchase and install two radar units for Douglas Coun
Superior Police Night Protection Project
Enhanced Neighborhood Crime Prevention through Increased Sex Offender Registration and Warrant Obsconder Policing along with Enhanced Radio, Camera, and Arrest Processing Technology Improvements.
Enhanced Neighborhood Crime Prevention through Increased Sex Offender Registration and Warrant Obsconder Policing along with Enhanced Radio,
The coalition is working in our community to assist in the essential change needed to reduce Sexual Assault, Domestic Violence, Youth Violence, and Stalking to Native American women, their families, and their community.
Tribal Domestic Violence and Sexual Assault Coalitions Program
NORTH CAROLINA COALITION AGAINST DOMESTIC VIOLENCE
This project provides training and technical assistance to the 92 NCCADV member programs and allied professionals. The provision of training and technical assistance helps to coordinate services on a statewide basis to victims of domestic viole
NCCADV Training and Technical Assistance Project
DISTRICT OF COLUMBIA COALITION AGAINST DOMESTIC VIOLENCE (THE)
Expanding Access to Community-based Technical Assistance and Training (EXACT)
ILLINOIS COALITION AGAINST DOMESTIC VIOLENCE
State Sexual Assault and Domestic Violence Coalition Grant Program
OVW Recovery Act State Sexual Assault and Domestic Violence Coalition Grant Program
OVW Recovery Act STOP Violence Against Women Formula Grant Program.  These federal funds enhance victim advocacy and criminal justice responses to violent crimes against women, including domestic violence, sexual assault, stalking and dating vi
Developing, implementing and strengthening effective law enforcement strategies to combat violent crimes against women, to improve the criminal justice system's response to violence against women, and to develop and strengthen victim services.
Recovery Act - OVW FY09 STOP Violence Against Women Formula Grant Program
Recovery Act - FY2009 STOP Violence Against Women Formula Grant Program - Funds will help creat and retain jobs for Victim Services personnel who respond to violent crimes against women.
Recovery Act - FY2009 STOP Violence Against Women Formula Grant Program
The goals and objectives of Maryland's Governor's Office of Crime Control & Prevention (GOCCP) in administering the Recovery Act S*T*O*P Violence Against Women Formula Grant (VARA) funding are to further the purposes of the Recovery Act—namel
Maryland's Recovery Act STOP Violence Against Women
The State will use STOP funds to promote a coordinated, multidisciplinary approach to enhance services and advocacy to victims, improve the criminal justice system's response, and promote effective law enforcement and prosecution strategies to
PUBLIC SAFETY, SOUTH CAROLINA DEPARTMENT OF
The South Carolina Department Public Safety, acting as the State Administrative Agency, administers and manages the Violence Against Women Act funds under the ARRA.  The purpose of the program in South Carolina is to develop or strengthen effec
Award Title: Recovery Act STOP Violence Against Women Formula Grant Program Description: The Recovery Act STOP will support communities in their efforts to retain criminal justice and victim services personnel that respond to violent crimes aga
Recovery Act STOP Violence Against Women  Formula Grant Program
The Alabama Department of Economic & Community Affairs will use these Recovery Act funds to award grants to governmental and nonprofit agencies to enhance programs that provide effective responses to violence against women.  These funds will as
Alabama Recovery Act STOP Violence Against Women Formula Grant Program
The Office of the Attorney General will continue its efforts to develop and strengthen coordinated community responses to violence against women in our State.  Through this program we will implement effective, victim-centered law enforcement, p
OVW-Recovery Act-Indian Grants to Tribal Governments Program
WOMEN'S SHELTER PROGRAM OF SAN LUIS OBISPO COUNTY
The overall purpose of the Transitional Housing Assistance Program is to provide transitional housing, short-term housing assistance (including rental or utility payments and assistance with related expenses such as payment of security depots a
SD NETWORK AGAINST FAMILY VIOLENCE & SEXUAL ASSAULT
This project supports programs that provide assistance to victims of domestic violence, dating violence, sexual assault, and stalking who are in need of transitional housing, short-term housing assistance, and related support services.  This pr
Recovery Act Transitional Housing Assistance Grant for Victims of Domestic Violence, Dating Violence, Stalking, or Sexual Assault
INTERIOR ALASKA CENTRE FOR NON VIOLENT LIVING
This award is to provide support services for victims of domestic violence residing in a 24 month transitional housing program.  In addition, this grant provides temporary rental assistance for victims in scatterered site transitional housing.
The YWCA Cass Clay will use funds from the OVW Recovery Act Transitional Housing Grant to provide housing and supportive services to women and women with children who are domestic violence survivors to assist them in achieving independence.  Su
OVW Recovery Act Transitional Housing Assistance Grant for Victims of Domestic Violence, Dating Violence, Stalking or Sexual Assault; U.S. Department of Justice Office on Violence Against Women.
Transitional Housing Grant for Victims of Domestic Violence providing housing services to victims fleeing domestic violence situations, providing transportation, couseling, child care services, case management and employment counseling.
CITIZENS AGAINST PHYSICAL AND SEXUAL ABUSE, INC.
The Recovery Act Transitional Housing Program increases the availability of transitional housing units and services for 21 additional families over the three year grant and enhances the existing support services by increasing our efforts in the
Transitional Housing for elder victims of domestic violence, sexual assault and stalking
Transitional Housing for Elder Victims of Domestic Violence, Sexual Assault and Stalking
Domestic Violence Transitional & Supportive Housing
This award is for transitional housing for victims of domestic violence or sexual assault. This award allows Safehouse to provide housing, job training, counseling, and other important services to help the victims towards self-sufficency.
The Sunnyside Neighborhood Association of Flagstaff Incorporated (SSAFI) will use the grant award to continue comprehensive community-based data-driven approaches to prevent and reduce violent crime.  SSAFI is expanding its current GENISIS-X ne
The GENISIS-X Program (Growth and Empowerment Neighborhood Initiative for Strengthening the Individual Success of eX-offenders)
Community Service Block Grant Stimulus - The monies will be used  for the reduction of poverty, the revitalization of low-income communities and the empowerment of low-income families and individuals within the territory of the Virgin Islands t
Community Service Block Grant Stimulus, American Recovery and Reinvestment Act (Recovery Act) of 2009.
1303 Hospital Ground, Knud Hansen Complex
LABOR AND INDUSTRIAL RELATIONS, HAWAII DEPARTMENT OF
Community Services Block Grant - American Recovery and Reinvestment Act of 2009
ARRA Supplemental Funding for the Child Care and Development Fund (CCDF). CCDF is utilized to increase availability, accessability, and affordability of child care.
ARRA SUPPLEMENTAL FUNDINGFOR THE CHILD CARE AND DEVELOPMENT FUND (CCDF) PROVIDE CHILD CARE FINANCIAL ASSISTANCE TO LOW-INCOME WORKING FAMILIES AND FUND ACTIVITIES TO IMPROVE THE QUALITY OF CHILD CARE
CHILD CARE & DEVELOPMENT FUND (CCDF) STIMULUS
The ARRA funds assisted the Hopi Child Care Program by allowing the program to purchase a playground shade for the children which is much needed for the summer months when children are out in the playground area to provide them with shade.  The
MASACHUSETTS DEPARTMENT OF EARLY EDUCATION & CARE
The Child Care Development Fund assists low-income families, families receiving temporary public assistance, and those transitioning from public assistance in obtaining child care so they can work or attend training/education.  The ARRA Child C
Child Care Development Fund (CCDF) - ARRA
PORT OF CORPUS CHRISTI AUTHORITY OF NUECES COUNTY, TEXAS
The project is the installation of a backbone fiber optic infrastructure for the transmission security related video and data
Port-wide Fiber Optic Infrastructure Installation
BROWNSVILLE NAVIGATION DISTRICT OF CAMERON COUNTY, TX
American Recovery and Reinvestment Act 3D Sonar Procurement
ORANGE COUNTY NAVIGATION AND PORT DISTRICT
American Recovery & Reinvestment Act Port Security Grant Program (ARRA PSGP)
American Recorvery and Reinvestment Act Port Secuirty Grant Program (ARRA PSGP)
American Recorvery and Reinvestment Act Port Security Grant Program (ARRA PSGP)
American Recovery and Reinvestment Act Port Security Grant Program (ARRA_PSGP) 0388
American Recovery and Reinvestment Act  - Port Security Grant Program (ARRA PSGP)
SOUTHEASTERN PENNSYLVANIA TRANSPORTATION AUTHORITY - SEPTA
NORTHEAST ILLINOIS REGIONAL COMMUTER RAILROAD CORPORATION
ARRA Transit Security Grant Program-Law Enforcement
American Recovery and Reinvestment Act Rail and Transit Security Grant Program-Law Enforcement (ARRA TSGP - LE)
SAN FRANCISCO BAY AREA RAPID TRANSIT DISTRICT
American Recovery and Reinvestment Act  Transit Security Grant Program Capital Projects (ARRA TSGP-CP)
The COPS Hiring Recovery Program (CHRP) provides the City of Oakland - Oakland Police Department (as a primary law enforcement authority within our jurisdiction) with grant funds to create and preserve law enforcement positions.  The CHRP funds
ST LOUIS OFFICE FOR DEVELOPMENTAL DISABILITIES RESOUCRES
The COPS Hiring Recovery Program (CHRP) award will allow the City of St. Louis to hire an additional 50 police officers that it otherwise would not have been able to.
The COPS Hiring Recovery Program (CHRP)provides funding directly to law enforcement agencies to hire and/or rehire career law enforcement officers in an effort to create and preserve jobs, and to increase their community police capacity and cri
The COPS Hiring Recovery Program (CHRP) provides funding directly to law enforcement agency's to hire law enforcement officers in an effort to create and preserve jobs. Salt Lake City Police Department will increase their community policing cap
Cops hiring recovery program(CHRP) provides funding directly to law enforcement agencies to hire and/or rehire career law enforcement officers in an effort to create and preserve jobs, and to increase thier community policing capacity and crime
The COPS Hiring Recovery Program (CHRP) provides funding directly to law enforcemtn agencies to hire and/or rehire career law enforcement officers in an effort to create and preserve jobs, and to increase their community policing capacity and c
The COPS Hiring Recover Program (CHRP) provides funds directly to law enforcement agencies to hire and/or rehire career law enforcement officers in an effort to create and preserve jobs and to increase their community policing capacity and crim
The funds will be used for crime prevention and for an electronic citation program for law enforcement, which will assist the entire criminal justice community.
Installation of fiber optic cable to connect the North Platte Police Department with the Lincoln County Sheriff's Office/County Court to allow secure, reliable and fast exchange of information, reports, pictures, booking information, drug traff
BJA FY 09 Recovery Act Edward Byrne Memorial Justice Assistance Grant Program Local Solicitation - Law Enforcement Information Sharing
The City of Los Angeles, the County of Los Angeles, and 75 jurisdictions within the County of Los Angeles are using their ARRA JAG allocations to fulfill the public safety needs of their individual jurisdictions. Examples of projects are law en
Police Eye Against Criminal Engagements with Police Interoperability
The Montgomery County Fiscal Court will purchase equipment for the Montgomery County Sheriff's Office, to acquire eight patrol rifles, and 12 AR-15 electric locking mounts for patrol vehicles.  The rifles will be equipped with carrying handles
Montgomery County Sheriff's Department Equipment Acqusition Project
Utilize funding to purchase law enforcement related equipment needed to prevent and control crime.
Socorro police department Patrol Vehicle Project and Socorro County Technology Project
This grant is authorized by ARRA of 2009 which will allow this agency to purchase and install cell block equipment, material and technological upgrades.
this projected funded the purchase of a commercial vehicle enforcement truck and a police canine unit.
The project would fund the purchase of a commercial vehicle enforcement truck and a police canine unit
Lebanon City Joint Recovery Act JAG Project
The City of Riviera Beach will use these funds to preserve a crime analyst and police technician position position in the City's Police Department. Both of these positions were in jeopardy of being eliminated.
The Village of Royal Palm Beach will enhance the surveillance capabilities of the Palm Beach County Sheriff's Office District 9 by purchasing a speed trailer, rifle and shotgun lights, thermal imager and night vision accessories.
Award Description NO FUNDS HAVE BEEN REQUESTED/RECEIVED AS OF THIS DATE Purpose The purpose of this project is ?to improve the functioning of the criminal justice system and to assist local . . . efforts to prevent or reduce crime and violence
Purchase of police vehicle and equipment for new officer
Purchase and install in car cameras and related software supplies
Grant to upgrade the City of Marianna's Police Department dispatch.
Marianna Police Department Dispatch and Reporting Technology Upgrade
The City of Bowling Green will purchase additional modern technology to both protect and assist its officers in their daily duties.  The Bowling Green Police Department intends to purchase approximately twenty-six (26) digital in-car cameras fo
Bowling Green Police Department/Warren County Attorney's Office Joint Project
FY 2009 Recovery Act JAG Program: Justice Assistance Grant will be used to incorporate underutilize law enforcement technologies in communication, global positioning systems, digital imaging, less lethal weapons and safety equipment to aid job
The city of Lynn, along with the Lynn Police Department will utilize funding to support The Economic Stimulus, Community Policing, and Technical Assistance project.  The primary goal of this project will be to hire two data clerks for a three y
City of Lynn Economic Stimulus, Community Policing and Technical Assistance Project
Edward Byrne local solicitation JAG recovery act grant
Gaffney pd fleet and narcotic unit upgrade
Funding to purchase equipment for Patrol to enhance their day to day operations.
Critical Incident Phone Negotiation Equipment
BJA FY09 Recovery Act Edward Byrne Memorial Justice Assistance Grant Program Local Solicitation. The Justice Assistance Grant (JAG) Program funded under the Recovery Act is the primary provider of federal criminal justice funding to state and l
Laramie County will use this award to fund three law enforcement activities relating to mental health and substance abuse.  One: Fund a mental health professional to conduct mental health evaluations and provide treatment systems in the county'
The county of Flathead will use its Fiscal Year 2009 Recovery Act JAG Grant in the amount of $106,197 to expand communication capabilities in the Northeast section of Flathead County which contains Glacier National Park and an unmanned Canadian
The American Recovery and Reinvestment Act Justice Assistance Grant (ARRA JAG) provides funding directly to law enforcmenet agencies for the procurement and implementation of equipment. The agency's is intent is to purchase aircards for compute
American Recovery and Reinvestment Justice Assistance Grant (ARRA JAG)
This grant was approved for the purpose of restoring one lost police officer position.  That officer is assigned to our Street Crimes Unit with a goal of fighting the onslaught of drugs and gangs in our high crime neighborhoods.  The position i
Recovery through System Improvement. Funds will be used to update equipment and improve community service.
The Lincoln County Sheriff's Department Edward Byrne Memorial Justice Assistance Grant Patrol Video Camera Program
The Lincoln County Sheriff's Dept Edward Byrne Memorial Justice Assistance Grant Patrol Video Camera Program
Shelby County, serving as the fiscal agent for this award, will share the Recovery Act JAG funds with five disparate jurisdictions within Shelby County. Each jurisdiction?s allocation will be used for activities and projects that will provide m
2009 Recovery Act Edward Byrne Justice Assistance Grant
Shawnee Police Department/Pottawatomie County Sheriff's Office equipment Enhancement Program.  This is to purchase much needed investigative equipment for the S.O., weapons and tasers.  The P.D. received tasers, road spikes, undercover wire sys
Shawnee Police Department/Pottawatomie County Sheriff's Office equipment Enhancement Program.
The Brownsville Police Department and the disparate agency will use all funds towards equipment and increase intelligence and communication across the county.
2009 Recovery Act Justice Assistance Grant
The Recovery Act:Edward Byrne Memorial Justice Assistance Grant Program provides funds directly to law enforcement agencies for the purpose of purchasing a broad range of equipment and information technology software and hardware to assist in t
The Recovery Act: Edward Bryne Memorial Justice Assistance Grant Program
tactical and interoperable communications with emergency responders, negotiators, and command staff. Replacement of critical equipment for patrol officers.
Cops Communication and critical equipment
Prime and sub-recipients are using the funds to purchase patrol vehicles otherwise unavailable
The City of Charleston will use its American Recovery Act JAG grant to boost its crime reduction and prevention strategy. The funds will be used by the Police Dept. to deploy and maintain a wireless network and camera system in high risk areas.
City of Charleston Police Department Project ONE-STOP
To improve law enforcement by hiring part-time deputy(s) to concentrate in high crime areas. It is expected that the additional deputy(s) will reduce overall crime in the targeted areas.
The County of San Luis Obispo will use the 2009 Recovery Act JAG funds to support the efforts of the following public safety agencies: the Sheriff's Office, the Chief Probation Officer, and the District Attorney.  These agencies will obtain com
Criminal Justice Automation Replacement Project
The purpose of this grant is to use the approved funds to purchase law enforcement equipment under the Law Enforcement Programs sections of approved expenditures. Our office will purchase two unmarked Chevrolet Impala police cruisers, one ITT N
Purchase Police Vehicles, Night Vision Technology and Related Equipment.
The disparate jurisdictions consisting of Napa County and the cities of Napa and American Canyon will use the Recovery Act JAG award in the amount of $203,335 to fund law enforcement initiatives.
Retain the position of Crime Analyst. Increase Analysts role in the department. Make Crime Analyst more visible to staff.Our main objective is to preserve this position through JAG funding for not only this year, but the next three years.  By k
The Town purchased eighteen (18) new radios for the East Haven Police Department.
The Cities of Vineland, Millville and Bridgeton and the County of Cumberland will utilize Recovery Act JAG Program funding to support the needs of the local law enforcement agencies in the areas of training, personnel, equipment, supplies and i
Branson Police Emergency Communications Project - To equip patrol vehicles with mobile computers and reporting technology.
Branson Police Emergency Communications Project
Police:  Upgrade and supplement current technology projects and the implementation of the department?s new Advanced Records Management System (ARMS). This will allow the department to disseminate information throughout the department and partic
FY09 Recovery Act JAG Public Safety Enhancement Project
Pinal County will use its Recovery Act JAG award to improve public safety through  increased traffic enforcement and to maintain criminal  prosecution and community-based probation supervision.
Improving traffic enforcement; maintaining criminal proscution; and maintaining probation supervision services in Pinal County, Arizona.
BJA FY 2009 RECOVERY ACT MEMORIAL JUSTICE ASSISTANCE GRANT PROGRAM - LOCAL SOLICITATION
The Justice Assistant Grant (JAG) Program funded under the Recovery Act is the primary provider of federal criminal justice funding to state and local jurisdictions.  Recovery JAG funds support all components of the criminal justice system, fro
Hennepin County FY09 JAG Stimulus Projects
Pre-trial: increase number of clients screened before advisory hearing by 50%; increase clients accepted to 2800; increase program compliance by 85%. Technology:improve system by electronic transmission of records instead of paper based; improv
BJA FY09 Recovery Act Edward Byrne Memorial Justice Assistance Grant Program Local Solicitation - Funding to provide substance abuse assessments, outpatient counseling, and drug screening for Adult Drug Court program participants.
Funds for the purchase of law enforcement equipment.
The City of Staunton will use its Fiscal Year 2009 Recovery Act JAG award to purchase a computer, gang tracking software and a property and evidence control room bar coding system for the Staunton Police Department.  The award will also be used
2009 RECOVERY ACT JAG PROGRAM:  JEFFERSON COUNTY SHERIFF'S DEPT. TO PURCHASE 24 P25 COMPATIBLE PORTABLE RADIOS FOR THE PATROL DIVISION.  THESE RADIOS ARE TO REPLACE CURENT WIDEBAND NON-CAPABLE OF BEING REPROGRAMMED TO NARROWBAND, WHICH IS NOW F
The disparate juridictions of Rutherford County, Town of Smyrna, and the cities of LaVergne and Murfreesboro will use these funds for equipment and related projects
This grant allows Fayette County to use grant funds to pay for law enforcement overtime hours worked.
The disparate jurisdictions consisteing of the Rapides Parish Sheriff's Office, the Cities of Alexandria and Pineville, and the Town of Glenmora will use these funds to purchase law enforcement equipment, supplies and technology to enhance law
Rapides Parish Recovery Act JAG Projects - Equipment Purchases
TO FUND THE ASHLEY COUNTY ADAM PROGRAM, A SUBSTANCE ABUSE EDUCATION AND PREVENTION PROGRAM FOR JUVENILES
FY 2009 Recovery Act Justice Assitance Grant Program
TO PROVIDE TRAINING AND EQUIPMENT TO ALL OF THE ACTIVE DUTY OFFICERS. THE OVERALL GOAL TO TO HAVE BETTER TRAINED OFFICERS AND TO HAVE THE NECESSARY EQUIPMENT TO KEEP THE COMMUNITY SAFE.
Funding under the FY 09 Recovery Act Edward Byrne Memorial Justice Assistance Grant Program Local Solicitation for law enforcement equipment purchases.  The Fayetteville Police Department has been awarded $207,129 for the purchase law enforceme
The Payne County Recovery Program establishes meaningful outcomes consistant with the goals of the Recovery Act through cost savings associated with acquiring technology and equipment.  The grant purchases an intoxilyzer for a neighboring polic
The disparate jurisdictions of Maricopa County and the cities of Avondale, Buckeye, Chandler, El Mirage, Gilbert, Glendale, Goodyear, Mesa, Peoria, Phoenix, Scottsdale, Surprise, Tempe, Tolleson and Youngtown will use their Recovery Act JAG awa
MIAMI-DADE COUNTY CRIMINAL JUSTICE SYSTEM EFFICIENCY AN
This system enhancement will address the critical need to automate the law enforcement reporting system using state of the art technology to greatly reduce an officers time on administrative tasks, returning the officer to the road and the comm
MIAMI-DADE COUNTY CRIMINAL JUSTICE SYSTEM EFFICIENCY AND ENHANCEMENT
technology enhancements for Riverhead Police Department.
2009 Riverhead Police Technology Initiative
'The COPS Hiring Recovery Program (CHRP ) provides funding directly to law enforcement agencies to hire and/ or rehire career law enforecment officers in an effort to create and preserve jobs, and to increase their community policing capacity a
The COPS Hiring Recovery Program (CHRP) provides funding directly to law enforcement agencies to hire and or rehire career law enforcement officers in a effort to create and preserve jobs, and to increase their community policing capacity and c
The COPS Hiring Recovery program (CHRP) provides funding directly to law enforcement angencies to hire and/or rehire career law enforcement officers in an effort to create and preserve jobs, and to increase their community policing capacity and
The COPS Hiring Recovery Program (CHRP) provided funding directly to law enforcement agencies to hire and or rehire career law enforcement officers.  This is the (CHRP) Grant. Cops Hiring Recovery Program.
The COPS Hiring Recovery Program (CHRP) provides funding directly to law enforcement officers agencies to hire and/or rehire career law enfrocement officers in an effort to create and preserve jobs, and to increase their community policing capa
The COPS Hiring Recovery Program (CHRP) provides funding directly to law enforcement agenices to hire and/or rehire career law enforcement officers in an effort to create and preserve jobs and to increase their community policing capacity and c
The COPS Hiring Recovery Program (CHRP) provides directly to law enforcement agencies to hire and/or rehire career law enforcement officers in an effort to create and preserve jobs, and to increase their community policing capacity and crime pr
'The COPS Hiring Recovery program (CHRP) provides funding directly to law enforcement agencies to hire career law enforcement officers in an effort to create and preserve jobs, and to increase their community policing capacity and crime prevent
The COPS Hiring Recovery Program provides funding directly to law enforcement agencies to hire and/or to rehire career law enforcement personnel.
The COPS Hiring Recovery Program (CHRP) provides funding directly to law enforcement agencies to hire and/or rehire career law enforcements officers.
COPS Hiring Recovery Program (CHRP) providing funding directly to enforcement agencies.
Henderson COPS 2009 (COPS Hiring Recovery Program (CHRP))
The COPS Hiring Recovery Program(CHRP)provides funding directly to law enforcement agencies to hire and/or rehire career law enforcement officers in an effort to create and preserve jobs, and to increase their community policing capacity and cr
The COPS Hiring Recovery Program (CHRP) provides funding directly to law enforcement agencies to  hire and/or rehire career law enforcement officers in an effort to create and preserve jobs, and to increase their community policing capacity and
The COPS Hiring Recovery Program (CHRP) provides funding directly to law enforcement agencies to hire and/or rehire career law enforcemnt officers in an effort to create and preserve jobs and to increase their community policing capacity and cr
The COPS Hiring Recovery Program (CHRP)provides funding directly to law Enforcment agencies to hire and / or rehire law enforcement officers.
The COPS Hiring Recovery Program (CRHP) provides funding directly to law enforcement agencies to hire and/or rehire career law enforcement officers in an effort to create and preserve jobs and to increase their community policing capacity and c
The Cops Hiring Recovery Program(COPS) providing funding directly to 1 law enforcement officer in an effort to divert lay-off and create a police officer position
The COPS Hiring Recovery Program (CHRP) provides funding directly to law enforement agencies to hire and/or rehire career law enforcement officers in an effort to create and preserve jobs, and to increase their community policing caapacity and
The COPS Hiring Recovery Program (CHRP) provides funding directly to Law Enforcement Agencies to hire/ Re-hire career Laqw Enforcement Officers in an effort create and preserve jobs, and increase thier community policing capacity and crime prev
'The COPS Hiring Recovery Program (CHRP)' provides funding directly to law enforcement agency's to hire and/or rehire career law enforcement officers in an effort to create and preserve jobs, and to increase their communtiy policing capacity an
The COPS hiring recovery program (CHRP) provides funding directly to law enforcement agencies to hire and/or rehire career law enforcement officers in an effort to create and preserve jobs.
'The COPS Hiring Recovery Program (CHRP)provides funding directly to law enforcement agencies to hire and/or rehire career law enforcement officers in an effort to create and preserve jobs, and to increase their community policing capacity and
The COPS Hiring Recovery Program provides funding directly to law enforcement agencies to hire or rehire career law enforcement officers in an effort to create and/or preserve jobs, increase/expand community policing, and further crime preventi
'The COPS Hiring Recovery Program (CHRP) provides funding directly to law enforcement agencies to hire and/or rehire career law enforcement officers in an effort to create and preserve jobs and to increase their community policing capacity and
The COPS Hiring Recovery Program (CHRP) provides funding directly to hire and/or rehire career law enforcement officers.
The Cops hiring recovery program(CHRP) provides funding directly to law enforcement agencies to hire and/or rehire career law enforcement officers in an effort to create and preserve jobs and to increase their community policing capacity and cr
The COPS Hiring Recovery Program (CHRP) provides funding directly to law enforcement agencies to hire and/ or rehire career law enforcement officersin an effort to create and preserve jobs, and to increase their community policing capacity and
Community Policing Award for officer hiring. Neighborhood Watch, community cleanups, youth programs.
The COPS Hiring Recovery Program (CHRP) provides funding directly to law enforcement agencies to hire and / or rehire career law enforcement officer's in an effort to create and preserve jobs, and to increase their community policing capacity a
The COPS Hiring Revocery Program (CHRP) provides funding directly to law enforcement agencies to hire and or rehire career law enforcement officers in an effort to create and preserve jobs, and to increase their community policing capacity and
PUBLIC SAFETY, SOUTH DAKOTA DEPARTMENT OF
Cops Hiring Recovery Program has provided funding to OSTDPS to hire 2 career law enforcement officers in an effort to increase the community policing capacity of the department.
The Cops Hiring Recovery Program CHRP provides funding directly to law enforcement agencies to hire and re-hire career law enforcement officers in an effort to create and preserve jobs, and to increase their community policing capacity and crim
The COPS Hiring Recovery Program provides funding directly to law enforcement agancies to hire and/ or rehire career law enforcement officers in an effort to create and preserve jobs, and to increase their community policing capacity and crime
The COPS Hiring Recovery Program [CHRP]provides funding directly to law enforcment agencies to hire and/or rehire career law enforcment officers in an effort to creat and preserve jobs, and to increase their community policing capacity and crim
The COPS Hiring Recovery Program (CHRP)provides funding directly to Law Enforcement agencies to hire and/or rehire career Law Enforcement Officers in an effort to create and preserve jobs, and to increase their community policing capacity and c
Public Facilities- Community facility- neighborhood center design and repairs. Economic Development- Business/kitchen incubator and/or facade enhancements. Housintg Rehabilitation- rehab for elderly/handicapped low/moderate income homeowners. D
Community Development Block Grant ARRA Entitlement Grant. Local use is intended for infrastructure improvements.
Community Development Block Grant ARRA Entitlement Grants (CDBG-R) (Recovery Act Funded)
SACRAMENTO HOUSING AND REDEVELOPMENT AGENCY
The Community Development Block Program Recovery (CDBG-R) funds will invest in: 1. Township 9 Infrastructure Design.  The purpose is to provide infrasturcture improvements to support affordable Housing. 2.  Four Public Service contract to suppo
Township 9 Infrastructure Design - Construction Self Help Housing - Public Service Volunteers of America - Public Service Lutheran Social Services - Public Service Salvation Army - Public Service
CDBG-R allocation:  1.  Housing Rehabilitation Loan Program  ($190,440) 2.  Minor Home Repair Grant Program ($111,780) 3.  Small Business Revolving Loan Program ($111,780)
Energy Efficiency Improvements to a 23 unit multifamily building occupied by low income to reduce housing costs
Housing First Energy Efficiency Improvements
CDBG-R funds are provided to states and local governments for primarily economic development, housing, infrastructure and other public facilities activities that will quickly spur further economic investment, increased energy efficiency and job
$183,902 in CDBG-R Funds.   The Department of Housing and Urban Development (HUD) awarded the City of Mountain View $183,902 in CDBG-R Funds on August 21, 2009.  The City has used the CDBG-R funding in combination with regular CDBG funding and
Maryce Freelen Green Administration Project
The CDBG-R award for the City of Palo Alto is $183,477.  It will be awarded to subrecipients in the following manner:  Shelter Network for the Haven Family House, $27,500, to provide transitional housing for low income homeless families ~ jobs
CDBG-R activites include public service, adminsitration and capital/rehabilitaiton projects
The award is CDBG-R Funding (Community Development Block Grant recovery funds).  A Substantial Amendment to City of Santa Clara Fiscal Year 2008-09 Annual Plan for the use of CDBG-R funds was added.   Two infrastructure, public facilities proje
Substantial Amendment to City of Santa Clara Fiscal Year 2008-09 Annual Plan for Use of CDBG-R Funding
The award name isCDBG Recovery (CDBG-R)and it is supplemental appropriation to entitlement communities to carry out eligible activities under the CDBG program.
Installation of water savings devices and energy savings devices at 100 units of low income housing family complexes.
Water and Energy Conservation - Eden Housing
Conduct community development activities through several programs benefitting low income persons in Pleasanton, California.  CDBG-R funds were used to coordinate health care access for the uninsured, provide hot meals for low-income persons and
CDBG-R activities include a wide variety of community development projects directed toward housing, neighborhood revitalization, economic development, and the provision of improved facilities and services.
The Community Development Block Program Recovery (CDBG-R) funds will invest in the Pearson Park & Ride Project.  The purpose of this project is to improve pedestrian walkways and create parking in a HUD established low-mod income area as part o
Storm drain improvements to alleviate flooding in low income neighborhoods.
Community Development Block Grant Recovery (CDBG-R) Program funds under the American Recovery and Reinvestment Act of 2009.  The City has invested these funds in infrastructure improvements.
CDBG-R funds will be used to implement a variety of ADA improvements throughout the City of Alhambra.  The ADA curb ramp project will increase mobility of disabled or elderly persons in the target area by installing appoximately 100 curb ramps,
The purpose of this program is to make necessary improvements (3 projects) to Arden Street in preparation of a larger development referred to as the El Monte Transit Village.  The El Monte Transit Village will result in the development of marke
2009 CDBG-R Arden Street Improvement Projects
Curb Ramp ADA Improvements Project at the following intersection locations on Northeast, Northwest, Southeast, and Southwest corners requiring improvements: Rindge & Plant, Grant & Green, Grant & Blossom, Blossom & Rockefeller, Green & Rockefel
Curb Ramp ADA Improvements Project and Commercial Rehab Program
Community Development Block Grant - Recovery funding for South Gate Park Infrastructure Project
The Bartolo Square North Neighborhood Street Improvement Project involves the construction and installment of a new polyvinyl chloride (PVC) 8? water main pipe lines to replace existing 8? cast iron pipes that are corroded. The new water main p
Purpose: To create suitable living environments, and to provide decent, affordable housing: Expected results: benefit 69 households with affordable housing and create 10 construction jobs.
The CDBG-R project provided for ADA improvements to five (5) city park facilities.
ADA Playground Resurfacing / Accessibility Improvements Project
The City of Oceanside will use Community Development Block Grant - Recovery Act(CDBG-R)  funds for capital improvement projects at facilities that provide services to defined benefit populations including women and children made homeless by dom
Community Development Block Grant - Recovery Act projects in the City of Oceanside, California
Replacing 63 roof-mounted air conditioner condenser units and 63 in-unit heaters at the lower-income Bella Vista Apartments on Los Feliz Drive in Thousand Oaks.
CDBG-R funds will be used to improve the Tustin Area Senior Center facility by replacing air conditioning and heating units, wall coverings, and flooring, all of which are original to the building when it was built in 1989.
Senior Center - HVAC, Flooring and Wall Covering
The City received an entitlement allocation of CDBG-R funds from the U.S. Department of Housing and Urban Development.  In accordance with the City's Substantial Amendment to the 2008-09 Action Plan, Paramount is using CDBG-R fund to implement
CDBG-R Sidewalk Improvement, Building Entry Improvements, Planning and Administration Projects
CDBG-R funds to acquire and construct missing sidewalk section within a low- moderate-income CDBG eligible neighborhood.
CDBG-R 14th Avenue Sidewalk Installation
Community Development Block Grant-Recovery  For ADA accessibility to services at City Hall, to include a new elevator and ADA accessible restroom.
Recovery funds will be used conjunction with regular CDBG funds for construction of a multi-purpose addition to Northeast Recreation and Community Center.
CDBG-R funds will be used to address the infrastructure needs in qualifying census tract areas with the reconstruction of streets and curbs in the City of Dover.  Funding for this project will maxmize job creation by creating jobs for contracto
The City of Gainesville will utilize the CDBG-R funds to fund a public infrastructure project, The Booker T. Washington Subdivision Roadway and Drainage Improvement project.  The proposed project is to provide roadway pavement restoration/recon
Booker T. Washington Subdivision Roadway and Drainage Improvement Public Infrastructure Project
Grant Award via Recovery Act of 2009 Program.
The Community Development Block Program Recovery (CDBG-R)funds will invest in the purchase of land adjacent to a structure that will become a cultural and arts education center in the City of Fort Pierce as well as economic development projects
structure course of SP-9.5.  Drainage improvements will be made as necessary to comply with current state regulations.  Planned deliverables include the retention of 3 low/mod skilled and unskilled laborer jobs for the course of the project.
Northeast Palm Bay CDBG-R Asphalt Paving and Road Construction Project
Community Development, Energy Efficiency Improvements, Senior Services
Community Development Block Grant ARRA Entitlement Grants (CDBG-R)(Recovery Act Funded)
The Town of Davie will utilize $49,513 to make upgrades and retrofit existing public facilities within the Towns's CDBG Target Areas to improve energy efficiency. The Town proposes to replace existing a/c units and lighting fixtures in the Neig
Public Service,Program Administration, Homebuyer Assistance,Homebuyer Rehabilitation
additional funding to create jobs and improve services.
The primary objective described by HUD in the ARRA of 2009, is for communities to invest in economic development, housing, infrastructure and other public facilities that will quickly spur economic investment, increased energy efficiency, and j
North Ave Phase I / State Street / Anderson  Street Resurfacing Projects
Community Development Block Grant-Recovery is providing funding for the Purchase-Rehab Program to aquire property, rehab said property and sell it to a single family that meets the low to moderate income eligiblity.  Funding also supports the a
CDBG-Recovery award will support the following activities:  Martin Luther King Center Expansion and Renovation, Commercial/Industrial Revolving Loan Fund, Targeted Rehabilitation Forgivable Loan Program and the Emergency Forgivable Loan Program
Targeted Rehabilitation Forgivable Loan program and Emergency Forgivable Loan Program and Commercial Industrial Revolving Loan Program
Project funding has been awarded through the American Recovery and Reinvestment Act (ARRA) of 2009, to achieve the ARRA's goals of job creation and renewed economic development, and the Department of Housing and Urban Development's (HUD's) goal
Community Development Block Grant - Recovery funds
108 District-wide Social, Emotional & Behavioral Curriculum
Community Development Block Grant - Recovery Act formula allocation
Community Development Block Grant Recovery Funds (CDBG-R)
Assist a new company with the purchase of heat treating equipment. The main focus of this facility will be the reconditioning of railroad car couplers by a process that rebuilds these components back to gauge.  These parts will then be resold b
Four activities, in addition to Planning and Administration, will be carried out through CDBG-R.   Activity #1 addresses the Recovery Act by fostering energy independence through the installation of geothermal heating, ventilation, and air cond
City of South Bend, IN CDBG-R Projects:  Activity #1 W. Washington Geothermal Project; Activity #2 Salvation Army Outreach Offices; Activity #3 Aging in Place Program; and Activity #4Housing Rehabilitation at 208 Chapin St.
Energy Efficiency upgrades and neighborhood sidewalk improvements.
Energy Efficiency upgrades and sidewalk improvements
Act #1: Neighborhood Infrastructure Improvement Program; Activity #2 Eco-Smart Housing Retrofit Program
The City of Bowling Green will use its CDBG-R entitlement funding to install storm water improvements in downtown Bowling Green.  The project area is located in the vicinity of 8th and State streets.  The project has been bid and awarded but co
Weatherization of 35 owner occupied low to moderate income housing units that will create temporary construction jobs.
1)Lower Ninth Ward Sustainable Infrastructure Project -  The city of New Orleans endures high annual rainfall and localized flooding and is currently employing an off-site management approach, which requires extensive infrastructure.  Our goal
)Lower Ninth Ward Sustainable Infrastructure Project -
The Community Development Block Grant Program Recovery (CDBG-R) funds will invest in the CDBG Target Area Sidewalk Repair and Improvement Program. Improving the sidewalks of the CDBG Target Area will motivate the area residents to walk more and
CDBG-R for Infrastructure project.  This project is part of a larger project to  improve a streetscape on Main Street between Academy Street and the Little Androscoggin River.  The ARRA portion of the project involves the  reconstruction that c
Community Development Block Grant - Recovery (CDBG-R)
The Town of Weymouth, MA funded a Neighborhood Paving Project with its American Recovery Reinvestment Act funds under its Community Development Block Grant (CDBG-R) Program.  The total funding amount under CDBG-R is $217,173.00.  The CDBG-R fun
Georgia, Kent, Verndale, Durant Road, Bates Avenue, Ree
CDBG-R funding for housing, community and economic development, and assistance for low- and moderate-income persons and special populations.
Long Pond Drive Sidewalk Accessibility Improvements
People/Families with of People with Physical Disabilities
CDBG-R funds will invest in the City of Royal Oak's public infrastructure by resufacing segements of E Third St and S Center St.  Public infrastructure improvement will also occur within the Devon Road right-of-way.
Road Resurfacing: E Third St & S Center St; Infrast Improv Devon Rd r.o.w.; program admin
A severe reduction in state revenue sharing and a decrease in property values resulting in lower property taxes collected have resulted in the City's General Fund no longer being able to support local street projects. Consequently, the lack of
Community Development Block Grant - Recovery
CDBG-R funding was awarded by HUD to carry out Housing Rehabilitation and Down Payment Assistance programs, and associated administration.
The Community Development Block Program Recovery (CDBG-R)award will invest in The White Street Project.  The purpose of this project is to pave one of the last unpaved streets in the City of Muskegon.
Funds allocated to Senior Citizens furnace replacement. The award date is the agreement between HUD and Clinton Township.  We received the Funding Approval/Agreement which states box 4. Date of use of funds is 6/26/2009.  The signature date of
Heritage Senior Center Furnace Replacement
Community Development/Neighborhood Revitalization/Energy Efficiency/Jobs - Central Minnesota Habitat for Humanity ? was selected by the City of St. Cloud and the St. Cloud Housing and Redevelopment Authority to receive $128,350 from the America
Eden Prairie Community Development received CDBG-R funds to be used for rehabilitation to benefit low income Eden Prairie residents. These funds were used by Frasier, City Hill Fellowship, and PROP.
The City of Springfield, MO proposes to utilize the CDBG-R funding to provide approximately 16,200 linear feet of sidewalk reconstruction in CDBG income eligible neighborhoods.  The areas were chosen because of the deteriorated condition of the
Family Enrichment Program and ADA Sidewalks Empire Elementary School area
The City of Bridgeton will use Community Development Block Grant-Recovery (CDBG-R) funds on behalf the Bridgeton Free Public Library in recognition of the critical services the Library provides to low and moderate income (LMI) persons and famil
Curbs & Sidewalks - Replace, add curb cuts(Handicap),for the safety and ease of passage for disabled, seniors and children within the CDBG Areas, prominently South Clinton Avenue
The CDBG-R award for the City of Asbury Park will provide funding for  Neighborhood Revitalization/ Infrastructure Improvements and the administrative costs associated with the reconstruction of curbs, sidewalks and pavement in selected locatio
Neighborhood Revitalization/ Infrastructure Improvements and Administration
Reconstruction and rehabilitationo of existing roadway in the Borough of Sayreville. The road was added to a 2008 project that we did not have the funds to complete.
Community Develop Block Grant Recovery projects to stimulate the economy with property acquisition for affordable housing, infrastructure improvements and economic development improvements.
CDBG-R Community Development and Infrastructure Projects
The Buffalo Urban Renewal agency administers the Community Development Block Grant - Recovery Grant (CDBG-R) activities include a variety of community development projects including funding in the amount of $1,355,345 for rehabilitation of owne
Owner Occupied Single & Multi Family Rehabilitation - Citywide,   Demolitions - Citywide,   Street Improvements - Citywide,   Sidewalk Improvements - Mid City Strategy Area,   Employment Training (YouthBuild),  and  General Administration
65 Niagara Sq., 920 City Hall (administrative office)
City of Elmira Community Development Block Grant Recovery Program
E Byrne Memorial Justice Assistance Grant.  This grant was awarded to seven disparate police departments.  The departments used the grant to purchase much needed equipment.  The equipment purchased consisted of: unmarked vehicle, mobile data te
Edward Byrne Memorial Justice Assistacne Grant (JAG) Program/Grant
This grant is being used for  computer programs during this reporting period.
The Superior Police Department will fund the overtime and backfill created by the staffing of the forensic computer and technology office.  The Douglas County Sheriffs Department will purchase a Total Station and associated hardware and softwar
FY2009 Recovery Act Jusice Assistance Grant Program
Interoperable communications information sharing and equiipment manufacturing installlation and support
Cranston Police Department Alcohol Related Crime Enforcement Support Initiative
Grant for the acquisition of hardware, software and licenses to install laptop computers in patrol cars
Grant award for new fully equipped police cruiser and PBTs.
Versailles Police Department New Cruiser and PBTs
The disparate jurisdictions of the City of Tulsa, Tulsa County, City of Bixby, City of Broken Arrow, City of Owasso, City of Sands Springs, and the City of Skiatook will use their Recovery Act JAG funds to support Tulsa County Sheriff*s Departm
Crime Site Imager, K-9 Vehicles, Vests, Command Post Tracker, Prisoner Transport Vehicle, Video and Audio systems, Cameras, Scanners, Auto-Tracking Crime Software, Computers, Polygraph Systems, Surveillance Equipment
Jefferson County Consortium Recovery Act Plan -- law enforcement crime prevention programs, technology, equipment and part-time personnel.
Jefferson County Consortium Recovery Act Plan
BJA FY09 Recovery Act Edward Byrne Memorial Justice Assistance Grant Program Local Solicitation  Palm Beach County received a direct award of $1,246,822 for the following nine (9) proposals: 1) the State Attorney?s Office for $60,000 for the Co
The objective of this award is to have two investigators to identify, investigate, apprehend, and successfully prosecute offender who use the internet, online communication systems, or other computer technologies to sexually exploit children
Benton County Sheriff's Office Internet Crimes Against Children
BJA FY 09 Recovery Act Edward Byrne Memorial Justice Grant Program Local Solicitation
The City of Casa Grande will use the Recovery Act JAG award to pay for overtime hours and fringe benefits for officers and sergeants who are conducting policing activities.
Community Policing  Crime Prevention Activities
Alliance Police Department and Box Butte County Sheriff's office will purchase necessary law enforcement equipment.
We have improved interdepartmental communication to create efficencies. We have increased safety to our deputies and the public by adding secrutiy cameras and intercoms in the court holding area. We will continue to use the new technolgy to imp
Interdepartmental Safety and communication Enhancement Project
Mitchell Area Law Enforcement Shooting Range Bullet Retention System.
The City of Trumann will use the Recovery Act JAG funds to purchase essential equipment for the police department.
Kershaw County communications and less lethal project. These funds are being used to support training and equipment enhancements to purchase radio equipment/ to comply with new fcc mandates, tasers for officers.
Kershaw County Communications and Less Lethal Project
OJJDP FY Recovery Act Local Youth Mentoring Initiative.  Sacramento County School-Based Mentoring Program.  The Sacramento County Office of Education (SCOE), in collaboration with community and school partners, will expand school-based mentorin
Sacramento County School-Based Mentoring Program
BIG BROTHERS BIG SISTERS COLUMBIA NORTHWEST
The purpose is to hire 3.0 FTE to expand mentor matches in Multnomah County, Oregon and Cowlitz County, Washington. This award will also allow additional opportunities to expand the mentoring opportunities available to underserved and diverse p
Big Brothers Big Sisters Columbia Northwest Mentoring Expansion Project
LUTHERAN SOCIAL SERVICES OF SOUTH DAKOTA
The Rural Mentor Program is a partnership between Lutheran Social Services of South Dakota and nine rural public school districts in Lincoln and Minnehaha Counties in South Dakota. Our project goal is to reduce juvenile offenses and school fail
School-Based Mentoring in Underserved Rural School Districts
Hillsborough County Board of County Commissioners will use FY 09 Recovery Act Byrne Competitive funds to support the Tampa/Hillsborough Community Anti-Gang Expansion and Enhancement (CAGEE) with the Safe Neighborhood Family Violence Treatment P
Expansion and Enhancement of Community Anti-Gang Initiative
JUDICIARY COURTS OF THE STATE OF FLORIDA
Targeting Violent Crimes and Gangs Through a Data-Driven Approach.  Funds from the BJA Discretionary Grants Program will be used to support prosecutors, paralegals, and trial coordinators for the Gang Unit and the Gun Violence Enforcement Team.
Targeting Violent Crimes and Gangs Through a Data Driven Approach
Under Category 6 of the Recovery Act Edward Byrne Competitive Grant Program, Nationwide Children's Hospital was awarded $541,190 to augment and expand an enhanced child advocacy center model.  The Center for Child and Family Advocacy (CCFA) is
Co-location of health-care providers and investigators to enhance support and justice for crimes committed against children and adolescents- A national model.
The City of Mansfield will use the grant award to retain three positions and stabilize budgetary issues to avoid reductions in essential services provided to the local community and the law enforcement agencies.  The city will use funds to: res
To create four new civilian positions in the Division of Police and to redeploy three sworn positions to perform active law enforcement duties.  This will improve the capacity of Lexington's Division of Police to prevent and reduce crime.
Recovery Act Byrne Competitive--Lexington Redeployment Project
BJA FY09 Recovery Act Edward Byrne Memorial Competitive Grant Program :  Hiring of Civilian Law Enforcement (Support Personnel)
The $660,000.00 ($330,000.00/year) will fund the salaries for two (2) detectives who will become full time members of the Violent Crimes and Firearms Task Force (VCFTF).  It will also fund the salary and benefits for four (4) entry level attorn
Allegheny County District Attorney - Violent Crimes and Firearms Task Force
Under Category V the city of Duluth will use the grant award to hire toqualified forensic evidence technicians: provide additional professional training to assist the Duluth Police department in bringing its evidence department up to 'best prac
Hiring Evidence Technicians for the Duluth Police Department
Baltimore's Crime Analysis Expansion Program seeks to provide a coordinated analytical response to promote public safety, reduce the occurrence of violent crime, and offer the greatest economic benefits for Baltimore City.  This will be achieve
Baltimore's Crime Analysis Expansion Program
This award will fund the cost of one forensic scientist position for 18 months.  The new forensic scientist position will be responsible soley for postmortem toxicology work, which will reduce the case bqacklog and bring caseloads and turnaroun
Enhancing Forensic Services with additional Toxicologist
PURPOSE: Under Category 1, the City of Vancouver will use this award to provide additional support to the Vancouver Safe Streets Safe Communities Anti-Gang Initiative.  The Vancouver Safe Streets Safe Communities Anti-Gang Initiative is a colla
Vancouver Safe Streets Safe Communities Anti-Gang Initiative
Reducing Mortgage Fraud and Crime Related to Vacant Properties
PARTNERSHIP FOR A DRUG-FREE AMERICA, INC.
Based on the model of its Meth360® program, the Partnership for a Drug-Free America will create and implement the Police And Communities Together (PACT 360) program as a law enforcement-led community prevention education system to deal with ex
This grant is designed to reduce the recidivism of Franklin County Jail inmates and return productive citizens to the community. Thirty-two (32) new individuals received services consisting of job readiness, job placement, vocational skills, co
The initiative we have entitled Improving Law Enforcement Investigations within the Village of Penn Yan will help us to provide an efficient, proactive approach in the areas of crime prevention as well as investigating criminal activity.  The f
Improving Law Enforcement Investigations within the Village of Penn Yan
Pulaski County has utilized this award to improve and enhance its rural detention and jail operations through the addition of staff for the Pulaski County Jail.
Enhancing Rural Corrections, Detention and Jail Operations.
This grant application is made under category one, Combating Rural Crime. Our project is designed to respond and prevent drug, illegal gang, and criminal activity. It is a multi-agency, multi-jurisdictional, and multi-disciplined approach based
600000 to create a police department to service Bolton and surrounding areas.
The District's Domestic Violence Program is very short staffed with limited Prosecutors.  This grant enables the program to concentrate on domestic violence in all 5 counties.  The goal of the program is to prosecute batters to the full extent
Domestic Violence Program in the 24th District
The award was granted for Sex Offender Registration Detective, Crimes Analyst/Evidence Technician, Information Sharing Reporting System
FY09 Recovery Act Rural Law Enforcement Assistance: Facilitating Rural Justice Information Sharing
1)	Fund the position of crime analyst for an additional two years at a total cost of $90,889.00  2)	Fund the purchase of six (6) subscriptions to the Lexis/Nexis database for use by investigators assigned to the Jackson County Project Safe Neig
Retention of the Jackson County Sheriff's Office Crime Analyst
The Cordele Police Department has retained five civilian staff positions.  These incumbents have been cross-trained with basic skills of analysts.  The department has used these funds to puchase and install 64 wireless video cameras and related
The Tohono O'odham Nation is awarded a grant from the Bureau of Justice Assistance, Assistance to Rural Law Enforcement to Combat Crime and Drugs Program, under Category (1) combat rural crime.  The funding activities will be conducted by the T
PROJECT TITLE: Operation First-Line Defense for Using Intelligence-Led Policing to Combat Narcotics Trafficking.  Solicitation Title:  BJA FY09 Recovery Act Rural Law Enforcement Assistance:  Combating Rural Crime
Creation of a Montana Department of Justice Drug Diversion Unit to address the growing problem of prescription drug abuse and misuse in the state of Montana.
The award is designed to increase the number of arrests for computer-related offenses; to increase the number of convictions for computer-related offenses, with special emphasis on crimes against a victim who is a minor; to increase the sentenc
Transforming a Rural County Jail into a Community Corrections Facility the project goals are 3: * To expand & Improve Operations *Improve the management of offender * Provide greater security for increase in the inmate population.
Facilitation of Move from a Rural County Jail to a Community Corrections Facility
Mackinac County will use this award to increase the number of interdications, drug and money siezures, and arrests for sales and possession of illegal narcotics in and around Mackinac County and the Strait's region.  Mackinac County will use th
Combating Drug in Mackinac County through SANE
To share information within our County with other agencies and build data bases that can be used to solve cases within Yell County. We anticipate that all finger print cards will be entered into a local data base of local criminals so that poss
The Assistance to Rural Law Enforcement to combated drugs and crime purpose is to decrease the high crime rate on the White Earth Reservation. The White Earth Police Department hired or reassigned three investigators to continue our investigati
BJA FY09 Recovery Act Rural Law Enforcement Assistance: Combating Rural Crime
Recovery Act Rural Law Enforcement Assistance: enhancing Rural Corrections, Detention, and Jail Operations.
Aberdeen's Community Corrections Enhancement and Diversion Program
BJA FY 2009 Recovery Act Assistance to Rural Law Enforcement to Combat Crime and Drugs: Enhancing Rural Corrections, Detention & Jail Operations.
Cat. III Enhancing Rural Corrections, Detention & Jail Operations
Goals:		The goals/objectives of this project are very simple and are as follows: 1. To improve applicant's capability to positively and correctly identify individuals that are the subject of action taken by the Adair County Sheriff's Office. 2.
Adair County Enhanced Criminal Identification Project
Assistance to Rural Law Enforcement to Combat Crime
Jail Inmate Education, Programs, and Corrections Enhancement Project to provide comprehensive inmate education and programming utilizing incarceration time to assist in breaking the cycle of recidivism.
Jail Inmate Education, Programs, and Corrections Enhancement Project
INTERNATIONAL ASSOCIATION OF CHIEFS OF POLICE
While the major goal of the Leading by Legacy Program is to provide training and technical assistance strategically targeted to address the needs of rural law enforcement agencies, it will also help to meet the goals of the Recovery Act by crea
Project Name or Title: Leadership and Managerial Training for Rural Law Enforcement Agencies
This project has two primary goals, within the over-arching Recovery Act objective of creating and sustaining jobs: • Assess the current state of justice information sharing in rural jurisdictions and provide strategic technical assistance by
Rural Law Enforcement Technology Assessment
Minnesota's crime victims compensation program used these funds to reimburse victims or their service providers for crime-related expenses such as medical costs, mental health counseling, funeral and burial costs, lost wages or loss of support.
FY09 Recovery Act- Victims of Crime Act (VOCA) Victim Compensation Formula Grant Program
Recovery Act - OVC FY 09 VOCA Victim Compensation Formula Grant Program. Funds to assist victims of violent crime with crime related medical, wage loss, counseling and rehabilitation.
Recovery Act - OVC FY 09 VOCA Compensation  Formula Grant Program
FY09 Recovery Act Victims of Crime Act (VOCA) Victim Compensation Formula Grant Program.  This program pays expenses and losses to or on behalf of individual victims of violent crime.  These expenses and losses include medical, counseling, fune
Compensation to innocent victims of crime for out-of-pocket losses and costs associated with administration.
EXECUTIVE OFFICE OF THE STATE OF SOUTH CAROLINA
The South Carolina Crime Victim Compensation program pays expenses and losses to or on behalf of individual victims of violent crime. The expenses and losses include medical, couseling, funeral bills and loss wages. These payments contribute to
State VOCA Victim Compensation Formula Grant Recovery Act Funds
1205 Pendleton Street,Room 401, EAB Bldg
Recovery Act - State Victim Compensation Formula Grant will be used to supplement state efforts to compensate crime victims.  New Jersey will use these funds to reimburse victims for crime related expenses, such as medical costs, mental health
Recovery Act - State Victim Compensation Formula Grant
This is for the Recovery Act OVC FY 09 VOCA Victim Compensation Formula Grant Program.  These funds will be used to assist victims of violent crime  with out of pocket losses as a result of the crime.  These expenses include medical, mental hea
Recovery Act Office For Victims of Crime FY 09 Victim Compensation Formula Grant.
The grant will provide financial assistance to and on behalf of eligible victims of violent crimes.  The funds will pay such things as medical and dental bills, mental health counseling, prescription drugs needed and loss of wages.  Funds are p
This Grant award provides funds from the American Recovery and Reinvestment Act of 2009 (the Recovery Act) to enhance State victim compensation payments to eligible crime victims.
To assist public and private non-profit agencies in providing services to crime victims.
350 East 500 South Suite 200 Salt Lake City 84111
The stated purposes of the Recovery Act are: to preserve and create jobs and promote economic recovery; to assist those most impacted by the recession; to provide investments needed to increase economic efficiency by spurring technological adva
This grant award provides funds from the American Recovery and Reinvestment Act of 2009 to enhance crime victim services in the State.  The Recovery Act - OVC FY09 Victims of Crime Act (VOCA) Victim Assistance Formula Grant Program funds are co
The State of Connecticut Judicial Branch, Office of Victim Services, plans to use Recovery Act VOCA Assistance Formula Grant Program funds to provide funding to subgrantees in the State of Connecticut for community based services to victims and
Recovery Act - OVC FY 09 VOCA Assistance Formula Grant Program
Recovery Act - OVC FY 09 VOCA Victim Assistance Formula Grant Program.
This grant award provides funds from the Recovery Act to support the provision of services including, but not limited to, 24 hotlines, crisis intervention, court accompaniment and assistance in preparing compensation claims to victims of crime.
RECOVERY ACT OVC FY 09 VOCA VICTIMS ASSISTANCE FORMULA GRANT
States will use Victim Assistance funds to support community-based and governmental organizations which serve crime victims.  Services include, but are not limited to crisis intervention, counseling, emergency shelter, criminal justice advocacy
The purpose of the Victim Assistance Recovery Act grant is to provide direct services to crime victims, maintaining the current level of statewide crime victim services.  Three agencies operating four programs will be able to maintain their cur
Recovery Act OVC FY09 Voca Victim Assistance Formula Grant
The COPS Hiring Recovery Program (CHRP) provides funding directly to law enforcement agency?s to hire and/or rehire career law enforcement officers in an effort to create and preserve jobs, and to increase their community policing capacity and
The COPS Hiring Recovery Program (CHRP) provides funding directly to law enforcement agencies to hire and/or rehire career law enforcement officers in an effort to create and preserve jobs, adn to increase thier community policing capacity and
The Recover Sct Preserves and creates jobs in law enforcement and creates economic recovery. The Somerville Police Dept. hired a skilled victim advocate for crisis intervention and liaison work to help victims of Domestic Violence.
Creating and Preserving Jobs in Law Enforcement
FY 09 RECOVERY ACT EDWARD BYRNE MEMORIAL JUSTICE ASSISTANCE GRANT PROGRAM LOCAL SOLICITATION
Winchester City Recovery Act Justice Assistance Grant
The City of Wilmington will use its Fiscal Year 2009 Recovery Act JAG grant to boost its crime reduction and prevention strategy. The funds will be used by the Wilmington Police Department (WPD) to enhance nine of its programs. The WPD will upg
The City of Rohnert Park will use JAG funds to retain officers within the police department.  Funding will provide a police presence in neighborhoods.  The goal is to deter criminal activity and prevent crime in the city.
The grant was awarded under a project to procure American source law enforcement equipment for the Farmington Police Department and San Juan County Sherrif's Department.  The Farmington Police Department plans to utilize the funds to purchase v
Award allows for the purshase of equipment for the police department.  Said equipment will help the department and help with recovery
FY 09 Recovery Act Edward Byne Memorial Justice Assistance Grant
The city of La Quinta will use its Recovery Act JAG funds to increase the police department's ability to effectively investigate and prosecute crimes. Specifically, the JAG funds will be used for officer overtime to continue the Latch-Key After
Latch-Key After School Patrol Program & Special Enforcement Equipment
Purchased new 2010 police cruiser in September 2009.
Purchase of equipment to enhance communications and intelligence gathering capabilities.
purposes are to preserve and create jobs and promote economic recovery; to assist those most impacted by the recession; to provide investments needed to increase economic efficiency by spurring technological advances in science and health
Recovery Act Edward Memorial Justice Assistance Grant Program Local Solicitation
The project has utilized funding to purchase communications equipment to upgrade systems and ensure interoperability.
Law Enforcement Equipment and technology
The Assumption Parish Sheriff's Office will increase the use of information sharing, radio interoperability and work towards a wireless mobile data solution among Federal, State, and Local multijurisdictional task force by purchasing P25 compat
Santa Barbara County Cumulative Crime Prevention Program
The Community Policing Retention and Enhancement Program
The Arcadia Police Department purchased a new Police Cruiser & all emergency equipment
Arcadia Police Vehicle & equipment Grant
The funds will be used to purchase of three cruisers and related equipment to keep the police fleet operation at optimum level, fund overtime for a Problem Oriented Policing team with a strategy to address crime, disorder and other quality of l
Town of Manchester 2009 Recovery Act JAG grant program
The City of University City plans on purchasing equipment to replace outdated and deteriorating equipment currently being used by the department and officers.
The town of Windsor used its Fiscal Year 2009 Recovery Act JAG award to improve traffic safety by purchasing equipment used for traffic enforcement.  The equipment purchased is three hand held Lidar guns and a solar powered stationary speed mon
Grant funds will be utilized to provide directed patrol activities as well as to purchase equipment to assist police officers in dealing with criminal activity.
FY 2009 Recovery Act Justice Assistance Grant Program.Purchase of digital capable radios to enance interoperability and officer safety.  As well as video and audio systems, cameras, scanners, auto tracking crime software, computers, plygraph sy
2009 Recovery Act Justice Assistance Grant Program
BJA FY09 Recovery Act Edward Byrne Memorial Assistance Grant, local Solicitation.
COP & Technology: Enhancing Criminal Justice
BYRNE/JAG Federal Stimulus Recovery grant
The Modesto Police Department will retain 3 Police Officer positions for Fiscal Years 2009-2010 and 2010-2011. These positions would otherwise be unfunded until the economy and City of Modesto revenue recovers. These funds will be used in a man
We use this grant to fund our Community Oriented Policing Project. These funds allow us to continue paying our deputies to go to community events and functions and educate the public on ways to prevent crime and stay safe.  We also use funds to
Our proposed program is to provide evidentiary advancements and public awareness as it relates to front line officer interactions with the public.   Based upon the formula allocation of funds to the Stuart Police Department we felt the best use
Recovery Act JAG Program - Evidentiary advancements and public awareness as it relates to front line officer interactions with the public.
Kennewick, Washington Police Department is the prime recipient of the 2009 ARRA JAG and is disseminating funds to 2 other agencies since we are disparate. Those agencies are Benton County, Washington Sheriff's Office and Richland, Washington Po
Kennewick, Washington Police Department 2009 ARRA JAG Program
Las Cruces Police Department has requested a purchase order be prepared for the purchase of the mobile operations center and surveillance equipment for Las Cruces Police department, the Tasers and cameras have been purchased for Dona Ana County
Recovery FY2009 Justice Assistance Grant Program
BJA FY09 Recovery Act Edward Bryne Memorial Justice Assistance Grant Program Local Government. To provide funding for police for patrol vehicles and equipment purchase.
BJA FY09 Recover Act Edward Byrne Memorial Justice Assistance Grant vehicle replacement/purchase computers
Polk County Sheriff's Office Uniform Replacement Progject.  We replaced old outdated uniforms for roughly 80 deputies.  This could not have been done without the grant funding that we received.
Polk County Sheriff's Office Uniform Replacement Project
This award is to create and retain jobs to support law enforcement programs and provide supplies and equipment to update and enhance the capabilities of local law enforcement in Solano County. The jobs created and retained include police office
Solano County Law Enforcement Job Creation, Job Retention, Budget Stabliziation and Service Enhancement Project
FY09 Recovery Act Edwrd Byrne Memorial Justice Assistance Grant Program Local Solicitation
ARRA - Byrne non-competitve funding which will be used for implementation of online tip reporting system, for software upgrades, equipment, a vehicle, and other crime fighting efforts.
The Capitola Police Department is developing a an Emergency Communications Enhancement Project to ensure adequate radio communications throughout the City for its law enforcement personnel. The police department's objective for this program is
Capitola Police Department Emergency Communications Enhancement Project
JAG award for technology improvements for the Monroe Police Deparment
To Purchase License Plate Recognition System, Digital X-Ray system, EOD-9 Bomb Suit, Automatic Vehicle Locator (AVL), Camcorder, Vehicle Tracker, In-Car Vedeo Camera, Laptop Replacement and Digital Voice Recorders.
The City of Lawrence, through the Lawrence Police Departmetn (LPD) will utilize FY2009 Recovery Act JAG award funds to support the LPD's Police Retention Program
Technology upgrade for the Town of Summerville, Police Department.
FY 09 recovery act justice assistance grant program   Additional information that was requested: The Berkeley County Sheriff's Office goals were to provide updated communications, enhance investigative evidence gathering, enhance crime preventi
The grant project falls within two purpose areas 1) Law Enforcement Programs and 2) Prosecution and Court programs.  The goals are essentially to insure continuation of core services to law enforcement in deterring crime.  The overall goal is t
Recovering Core Services in Law Enforcement
BJA FY 09 Recovery Act Edward Byrne Memorial Justice Assistance Grant Program Local Solicitation: JAG Recovery grant to be used for law enforcement, prosecutorial, and court programs and equipment in order to provide effective criminal justice
1) Equip all active deputies with ballistic vests (never issued or currently have a vest that is well past its recommended service life).  2) Significantly increase the number of patrol vehicles with video and audio recording capabilities.  3)
Recovery Act 2009 Edward Byrne Memorial Assistance Grant
In Car & Body Worn Digital Cameras and Media Storage
Officer safety and efficency. The City of Prattville Police and the Autauga County Sheriff?s Office, in join collaboration, are using federal grant funds to purchase equipment to focus on safety and efficiency.
The purpose of this program is to improve the quality of life of the citizens in and around the city of Anderson, South Carolina, by means of pro-active arrests, convictions, and incarceration of offenders, thereby removing the perpetrators of
Overtime Funding for the Operation of the Street Level Criminal Apprehension Program
The award will be used to support a community outreach program, enhance professional development and for the purchase of equipment.
Community Outreach Project, Professional Development, and Equipment Purchase Program.
The City of Seattle, serving as the fiscal agent for this award, will share the fiscal year 2009 Recovery Act JAG award with 18 disparate jurisdictions within King County. In a disparate situation, the units of local government must apply for a
Edward Byrne Memorial Justice Assistance Grant Program Local Solicitation
The funds will provide information and communications infrastructure that will allow our Police, Sheriff, District Attorney, and Indigent Defense Services of the Administrative Office of the Courts more cost-efficient and effective ways to bett
Byrne Memorial Justice Assistance Grant Formula Program
Byrne Justice Assitance Grant Recovery Local Assistance
To purchase equipment and technology for the Police Department that increases operational efficiency, provides officers with much-needed replacements of older, obsolete equipment.
Upgrade the need to additional officer safety, evidence collection, crime prevention, and report writing.
Implementation of shared digital mugshot system; equipment additions to in-car video system; purchase of body worn digital video equipment for undercover use; mobile data and TraCS software interface for use in writing traffic and ordinance cit
CR 815/ANNEEWAKEE RD BRIDGE AT ANNEEWAKEE CREEK
SR 570 FR W CORP LIMITS OF MCCOMB EAST .9 MI                 NOTE: P.E. IS 100838
Salem Street Bridge over Rt 10, Deck Replacement
Bridge Deck Replacement Program Rt 159 WB over Rt 46 EB, Construction
The funding from this grant will be used to finance the construction of wastewater treatment facilities related appurtenances and its associated infrastructure, green infrastructure, nonpoint source projects, estuary projects and program admini
ND 1804 - From Beaver Creek W TO E BN Overpass
GENERAL ADMINISTRATION, WASHINGTON DEPARTMENT OF
The State of Washington Department of General Administration received funds through the American Recovery and Reinvestment Act of 2009 (ARRA) to pay costs associated with the distribution of USDA foods donated for use in The Emergency Food Assi
State of Washington TEFAP CAP Recovery ACT
Replace HVAC Systems at Klamath Basin NWRC
YERBA BUENA ENGINEERING & CONSTRUCTION INC
Project consists of providing all labor, materials, & equipment required to remove and replace existing  Long Beach CSMS Bldgs, F, D, B, & C  roof and HVAC systems.  Work will include:  Replacement of existing roof systems and installation of n
ATMS/ATIS: WESTCHESTER COUNTY PARKWAYS TRAFFIC SENSORS
Development of economically viable, highly integrated and modular solar power conversion, control, and communication architecture to enable higher penetration of solar power in the electric grid
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). The purpose of this proposal is to acquire Optically Stimulated Luminescence (OSL) dates from whole cobbles within raised beach ridges and boulder
Constraining the Deglaciation of the Antarctic Peninsula Using OSL Dated Beach Deposits
This project is a collaborative biodiversity informatics that builds on strengths at the MT James Entomological Collections (JEC) at Washington State Univrsity and Western Washington University.  This project will complete the computerization,
In this experimental program highly excited atoms are exposed to microwave fields with two goals. The first is to understand how a many level atomic system interacts with a radiation field over a broad range of atomic states, from one in which
Office of the Secretary of Housing and Urban Development
NOTRE DAME HOUSING DEVELOPMENT FUND CO INC
The Section 8 Housing Assistance Payments program is a rent subsidy program for eligible low-income families that makes up the difference between what a family can afford (usually 30 percent of household income) and the market rent for suitable
Funds allocated to assist low income homeowners with substantial repairs and job training programs for hard to employ residents.
REPLACEMENT OF CR 77 BRIDGE OVER RONDOUT CREEK
UPGRADE 60 WESTCHESTER CO SIGNALS TO 2070 TYPE CONTROLLERS
RUSTIC RAIL REPLACEMENT WESTCHESTER COUNTY
SFY 09/10 PMI PAVING; ROCKLAND AND WESTCHESTER COUNTIES
'Bicycle Sharing Program','Purchase and install 40 SmartBike stations and 480 SmartBikes throughout the city'
Bicycle Sharing Program (Phase 2 Smartbike)
'Streetscape Construction','Upgrade 25 block faces to comply with Downtown Streetscape and Streetlight regulation and promote economic development'
Light Truck and Utility Vehicle Manufacturing
Wahpeton - 4th Avenue S from 6th St. S to 11th St. S
Wahpeton - 7th Street N from 8th Ave N to 16th Ave N
Lawn and Garden Tractor and Home Lawn and Garden Equipment Manufacturing
CONNECTICUT ASSOCIATION FOR COMMUNITY ACTION
CSBG T/TA ARRA to provide Strategic Planning and Coordination resulting in improved information and reporting systems through consistent sharing of best practices (including monitoring ARRA data collection and reporting to fully document commun
CSBG T & TA Supported by the American Recovery and Reinvestment Act of 2009
Functional integrals were introduced by R. P. Feynman as a conceptual tool for the understanding of the quantum field theory of elementary particle physics. They provide a bridge from classical mechanics and field theory to their quantum counte
Measures on function spaces, statistical mechanics and the rigorous renormalization group
Non-technical: The project addresses basic research issues in a topical area of materials and chemical sciences with technological relevance. The success of this project is likely to have impacts on the advancement of the emerging area of spint
Manganese-Doping During Germanium Quantum Dot Self-Assembly for Spintronics Applications
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  Using a participatory action research model the research team will investigate the roles, strengths, and needs of Alaska Native grandparents resi
From Their Perspective Alaskan Grandparents' Roles, Strengths, and Needs
Investment in local Community Action Agencies to enhance communications and provide training and technical assistance:  Funds are being used to implement major website renovations to help clients find services through their local Community Acti
CSBG T&TA:  Supported by the American Recovery and Reinvestment Act of 2009
ARRA Strengthening Communities Fund Nonprofits Capacity Building Program - The goal of this program is to build the capacity of our nonprofit partners in order to address the broad economic recovery issues present our community, including helpi
ARRA 2009 SCF - NON-PROFIT CAPACITY BUILDING PROGRAM
ARRA funds for Head Start Cost of Living Adjustments (COLA) in accordance with FY 2009 Funding guidance ACF-PI-HS-09-06.
This award provides ARRA funds for Early Head Start Quality Improvement and Cost of Living Adjustments (COLA) in accordance with FY 2009 Funding guidance ACF-PI-HS-09-06.  Early Head Start provides family-centered services for low-income famili
The award provides for ARRA cost of Living Adjustment (COLA), and Quality Improvement funding consistent with the provisions of Section 640(a)95) of the Head Start Act for the Head Start and Early Head Start program. Head Start promotes the sch
ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act.  80 children were served with this funding.  We have 5 classroom at four different sites.  Our Bin
ARRA COLA and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act to create 1 position as well as provide partial benefits to all staff and pay for tuition and books for HS and EHS staff.  Gila
Head Start Cost of Living Adjustments and Quality Improvements.  Early Head Start Cost of Living Adjustments and Quality Improvement.
Prairie Band Potawatomi Nation Early Childhood Education Center.  Head Start and Early Head Start.
This award provides for ARRA Cost of Living Adjustment (COLA), to Head Start staff and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Head Start program. Head Start promotes the sch
ARRA funds were used to provide COLA increases for Head Start staff in accordance with the FY 2009 Funding Guidance ACF-PI-HS-09-06 dated 4/2/09; to provide training; and program improvements.
OREGON CHILD DEVELOPMENT COALITION, INC.
This award provides for ARRA Cost of Living Adjustment (COLA) and Quality Improvement Funding for Migrant and Seasonal Head Start Programs consistent with the provisions of Section 640(a)(5)of the Head Start Act for the Head Start and/or Early
ARRA Cost of Living Adjustment(COLA), and Quality Improvement Funding consistent with the provision of section 640 (a)(5) of the Head Start Act
ARRA funds will be used to supplement but not increase current staff's pay.  The QI funds will be awarded to staff as an incentive to pursue their educational goals and to contract with persons to be in the classroom while staff attend classes
This award provides for ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act for the Migrant Seasonal Head Start program. Head Start promotes the school
Award Title: ARRA COLA and Quality Improvement. The overall purpose of this funding is three fold. Number one is to provide a one time cost of living to the staff of the Ute Tribe Head Start program.  Each employee will receive a monthly stimul
Quailty Improvement and Cost of Living funds for Ute Indian Tribe Head Start program
Head Start Program Improvement Award for 2009/2010 Year.
Head Start- full year, Cola Raises and Training
The goal of this program is to build the capacity of our nonprofit partners in order to address the broad economic recovery issues present our community, including helping low-income individuals secure and retain employment, earn higher wages,
ARRA Strengthening Communities Fund Nonprofits Capacity Building Program    The goal of this program is to build the capacity of our nonprofit partners in order to address the broad economic recovery issues present our community, including help
ARRA Strengthening Communities Fund Nonprofits Capacity Building Program   The goal of this program is to build the capacity of nonprofit partners in order to address the broad economic recovery issues present in our community, including helpin
ARRA Strengthening Communities Fund State, Local, and Tribal Government Capacity Building Program: This award is made to State, city, county, and Indian/Native American Tribal governments (or organizations designated by such governments) in ord
ARRA of 2009 Strengthening Communities Fund State, Local, and Tribal Government Capacity Building Program
The goal of the program is to build our capacity to partner with community-based and faith-based non-profits and to provide training and technical assistance to help nonprofits improve their core capacities which will help them to better serve
This funding will provide economic stimulus to the nation while furthering the ACF mission to promote the economic and social well-being of children, youth, families, and communities.The objectives of the Strengthening Communities Fund (SCF) ar
NATIONAL ASSOCIATION FOR STATE COMMUNITY SERVICES PROGRAMS
To support performance training and technical assistance on data collection, analysis and dissemination issues faced by State community services programs within the CSBG Network in response to the American Recovery and Reinvestment Act of 2009
Training and technical assistance program: Capacity Building for Ongoing Community Services Block Grant Programs and Strategic Planning and Coordination. The purpose of this grant is to assess the needs of all four Community Action Agencies in
Purpose: Iowa Community Action Association (ICAA) will provide technical assistance to the 18 community action agencies in Iowa to assist in the process of informing communities of local services supported by ARRA, document and communicate comm
CSBG T&TA: Supported by the American Recovery and Reinvestment Act of 2009
Project Description: Nevada?s ARRA Supported CSBG T&TA program works with Community Action Agencies to conduct the following activities:   ?	Work to assure that Nevada CAA?s have put in place an Agency Strategic Plan.   ?	Update the NCAA websit
UTAH COMMUNITY ACTION PARTNERSHIP ASSOCIATION, INC.
In order to continue to assist Utah?s CAAs, Community Action Partnership of Utah will provide a series of services that will build awareness of poverty issues and strengthen the Community Action Network in Utah.  Community Action Partnership of
CSBG T/TA Program: Strategic Planning & Coordination supported by the ARRA of 2009
Energy Efficiency and Renewable Energy, Recovery
The goal of this project is to develop and test a new method for measuring the rate of metamorphic processes including nucleation, growth, and strain.  We hypothesize that the Mn content of garnet subvolumes will correlate with age.  We propose
The City of Santa Rosa Wastewater Treatment Facility Improvement Project requires significant improvements to meet the National Pollutant Discharge Elimination Systems(NPDES) requirements; and meet anticipated limits for land application of sol
Santa Rosa Wastewater Treatment Facility Improvements
Construction of Wastewater Treatment Plant that services the Village of Ruidoso and the City of Ruidoso Downs in Lincoln County, Nre Mexico.  Both Ruidoso and Ruidoso Downs are tourist based communities and population may at times rise to 40,00
BRIDGE APPROACH SLAB REPAIR (I88 EAST OF ONEONTA)
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  On March 24, 1989, the tanker vessel Exxon Valdez ran aground on Bligh Reef, a well-marked navigational hazard in the Valdez Arm of Prince Willia
Collaborative Research to Investigate and Document Social Impacts of High-Stakes Litigation Resolution in a Renewable Resource Community
The Economic Recovery in ACTION project is a two-year statewide initiative geared toward ensuring the effectiveness of the state's Community Action network in utilizing, communicating, and documenting the impact of American Recovery and Reinves
CSBG T & TA Program: Capacity Building for Ongoing CSBG Supported by ARRA of 2009
The Arkansas Department of Environmental Quality was awarded a State Clean Diesel Program Grant to fund a retrofit, engine upgrade, engine and equipment replacement and idling reduction technology program targeting public, non-profit and privat
Arkansas Diesel Emissions Reduction Funding Assistance Program
The Service requires contractor assistance to successfully implement, execute and / or mointor the braod array of reuirements outlined in the implementing guidance and various memos issued by OMB and the Department of the Interior, as well as o
Highway Infrastructure Investment for the Puerto Rico Highway Program.  This project consist in the Pavement Rehabilitation and Minor Repairs on the South Region, Unit I.  This highway improvement is a Restoration and Rehabilitation (4R)
Pavement Rehabilitation and Minor Repairs South Region, Unit I
Pavement Rehabilitation and Minor Repairs Metro Region, Unit I.  This highway improvment is a Restoration and Rehabilitation (4R)
Pavement Rehabilitation and Minor Repairs Metro Region, Unit I
Highway Infrastructure Investment for the Puerto Rico Highway Program.  This project consist in the Pavement Rehabilitation and Minor Repairs East Region, Unit IV.  This highway improvement is a Restoration and Rehabilitation (4R)
Pavement Rehabilitation and Minor Repairs, East Region Unit IV
Highway Infrastructure Investment for the Puerto Rico Highway Program.  This project consist in the  Pavement Rehabilitation and Minor Repairs on Metro Region, Unit III.  This highway improvment is considered as a Restoration and Rehabilitation
Pavement Rehabilitation and Minor Repairs Metro Region, Unit III
When behavior thought to be characteristic of humans alone, is found in other animals using carefully controlled experiments, it may not be necessary to posit complex theories that are difficult to test. In the present proposal we will investig
WIA Supplemental Youth Services program gives youth between the ages of 14 and 24 the opportunity to gain work experience, good work habits while at the same time earning money to purchase clothes and school supplies. The youth worked closely w
DOL WIA Supplemental Youth Services under ARRA
SH 48, RIGBY HIGH SCHOOL TO YELLOWSTONE HWY
SH 7, N FK CLEARWATER RV BR, CLEARWATER CO
STC-5705, BENEWAH CREEK RD PHS 1, BENEWAH CO
STC-1777, 1ST EAST; SCL TO HWY 30, BANCROFT
STC-1720, S PLEASANT VALLEY RD, POWER CO
The University of Michigan School of Public Health is committed to being a leading contributor to the achievement of the national Healthy People in Healthy Communities objectives, as outlined in Healthy People 2010. The second goal of Healthy
EMPLOYMENT DEVELOPMENT, CALIFORNIA DEPARTMENT OF
WIA Adult,Youth, Dislocated Workers Formula.      WIA Dislocated Workers $221,906,888.00, CFDA 17.260; WIA Youth $186,622,034.00, CFDA 17.259; and WIA Adult $80,117,954.00, CFDA 17.258.
WIA Youth, Adult, and Dislocated Worker Formula Combined.
LABOR & EMPLOYMENT, COLORADO DEPARTMENT OF
1.RECOVERY-ACT-WORKFORCE INVESTMENT ACT (WIA)-DISLOCATED WORKERS FY09 FORMULA-STATES 09-A200-ARDZ-4123-5DWRI-000/17.260/$14,464,916.002. RECOVERY-ACT-WIA-ADULT FY09 ACTIVITIES-STATES 09-A200-ARDY-4123-5ADR1-000/17.258 /$4,792,362.00 3. RECOVERY
RECOVERY-ACT-WORKFORCE INVESTMENT ACT-DISLOCATED WORKERS FY09/RECOVERY-ACT-WIA-ADULT/RECOVERY-ACT-WIA-YOUTH FY09
WORKFORCE INNOVATION, FLORIDA AGENCY FOR
ARRA Workforce Investment Act (WIA) Dislocated Worker $80,551,937, CFDA 17.260 to provide employment and training activities for workers that have lost their jobs as a result of plant/business closures and layoffs: WIA Youth $42,873,265, CFDA 1
Recovery Act-WIA Adult-$2,702,158.00, CFDA 17.258; Recovery Act-WIA Dislocated Worker $5,203,888.00, CFDA 17.260; Recovery Act-WIA Youth $7,121,714.00, CFDA 17.259; WIA Adult Grants:  To provide a variety of work-related employment and training
WIA YOUTH-ARRA CFDA # 17.259 Total Award Amount $2,918,025:  Provide summer employment opportunities to youth ages 14-24 to help them attain work readiness skills through work experiences and for older youth the skills needed to obtain permanen
WIA Program - Youth/Adult/Dislocated Worker
WIA Dislocated Workers 6,023,463 CFDA 17.260; WIA Youth $ 8,708,036 CFDA 17.259; and WIA Adult  $  3,650,170 CFDA 17.258
WORKFORCE INVESTMENT ACT (Youth, Adult, and Dislocated Worker)
WIA Youth Formula Grants - States $2,918,025, CFDA #17.259; WIA Dislocated Workers Formula Grants-States $1,749,098, CFDA #17.260; and WIA Adult Formula Grants -States $1,234,406, CFDA #17.258.
CRIT WIA Youth Program- Work Experience & Classroom Training.
To provide summer youth employment opportunities, work readiness skills training and year-round services to Indian and Native Youth
To provide summer youth employment opportunities, and work readiness skills training, to Indian and Native American youth under Section 166 of the Workforce Investment Act.
Summer Youth Employment and Training Program
TO PROVIDE SUMMER YOUTH EMPLOYMENT OPPORTUNITIES, WORK READINESS SKILLS TRAINING AND YEAR ROUND SERVICES TO INDIAN AND NATIVE AMERICANS YOUTH UNDER SECTION 166 OF THE WORKFORCE INVESTMENT ACT.
Native American youth and assisting them with summer employment, job readiness skills, dropout prevention, leadership skills and culturally-relevant activities.
The Yankton Sioux Tribe is on Cost reimbursement.To provide youth employment opportunities,work readiness skills training for native american youth under section 166 of the workforce investment act.
Ihankton Nation Employment & Training Program
Recovery Act WIA-Youth Activities for Native Americans
Provide youth employment and work readiness skills training for 15 native american youth
Employment and training for Native American Youth
To foster individual economic self sufficiency; provide training in meaningful part-time opportunities in community service activities for unemployed low-income persons who are age 55 years of age or older, particularly persons who have poor em
The SCSEP grant  funded through ARRA is to support additional training and employment opportunities for unemployed low-income seniors that are 55 and older. The grant will expand the number of SCSEP participants assigned to community service wo
Programs that provide subsidized, part-time, community service work-based training for low-income persons age 55+ who have poor employment prospects.  It is intended that these community service experiences serve as a bridge to other employment
SCSEP-American Recovery Act - This program will provide part time community employment to individuals aged 55 and over, with poor employment prospects.
SCSEP - American Recovery Act (Stimulus)
ARRA provided funding to serve additional unemployed low-income senior citizens as part of the Senior Community Service Employment Program (SCSEP).  SCSEP is a community service and work based training program for older workers.  It was authori
ARRA Title V Senior Community Service Employment Program
To provide subsidized, part-time, community service work-based training for low-income persons age 55 or older who have poor employment prospects. It is intended that these community service experiences serve as a bridge to other employment pos
Fifteen local Area Agencies on Aging (AAAs) and Experience Works will enroll a minimum of 105 individuals to receive work experience training at public and private non-profit community service agencies.  These individuals will receive $7.25 pe
ARRA - SENIOR COMMUNITY SERVICE EMPLOYMENT PROGRAM (SCSEP)
Older Workers Program - To foster individual economic self sufficiency; provide training in meaningful part-time opportunities in community service activities for unemployed low-income persons who are age 55 years of age or older, particularly
Senior Community Service Employment Program (SCSEP) - American Recovery Act (Stimulus)
The overall purpose of this grant is to create job training/community service activities for eligible participants, persons 55 and older with low income, and with host agencies.  The expected outcome is unsubsidized employment of these particip
Senior Community Service Employment Program (SCSEP - Older Workers Program)
Purchase Digital dashboard camera systems for police cruisers to replace outdated VHScameras
Purchase of police cruisers dash cameras and administrative overtime
The Broomfield Police Department will be using this grant to fund one otherwise frozen Police Officer-Detention position.  The Police Department, in conjunction with the City and County of Broomfield Human Resources Division, will advertise, in
Money Provided to pay overtime to trained officers's to make drug arrest when the time exceeds their normal working hours. Equipment purchased will be used to transport officers from community to community through wooded areas and to better equ
The Kinston Department of Public Safety and the Lenoir County Sheriff Department will enhance their ability to better serve the citizens $ protect their officers, as it relates to this project, by procuring & implementing proven technology. Wok
Funds will be used to purchase crime crameras and protective vest.
Equipement Grant to purchase in car cameras
Community Policing through a Rapid response
JAG ARRA Grant funds will be used to fund 10 new jobs and retain 2 jobs.  AVL/GPS equipment will be purchased for Cobb County Sheriff's Office to increase response time.  Uniforms and equipment will be purchased for eight new deputies to allow
Job Creation/Retention and Equipment Purchases
Joint Williston PD and Williams County S.O. Safety Award
Joint Williston PD and Williams S.O. Safety Award
ARRA JAG Grant for a Automated Mobile License Plate Reader Program
Edward Byrne JAG Progam is to facilitate the installation of mobile data upgrade systems and to facilitate compliance with ANSI Safety regulations with regards to traffic vests and coats, as well as to provide officers with proper bullet-proof
Coweta County and Newnan City Recovery Act Justice Assistance Grant Program
The grant program is authorized by the American Recovery and Reinvestment Act of 2009. The stated purposes of the Recovery Act are:  to preserve and create jobs and promote economic recovery; to assist those most impacted by the recession; to p
Equipment, Supplies, Overtime, and Youth Services Program
Award Description Citizen volunteers have relieved patrol officers of routine tasks such as vacation security checks, morning and afternoon patrols around six schools, patrols of the City parks and bike trails, and close patrol in high crime ar
2009 (JAG) Local Solicitation for funds to help defray the cost of the salary for the Rolla Community Police Officer/ Volunteers in Police Service Program Assistant Coordinator
The Recovery Act provides the U.S. Department of Justice with funding for grants to assist state, local and tribal law enforcement, to combat violence against women, to fight internet crimes against children, to improve the functioning of the c
Recovery Act Justice Assistance Grant (JAG)
The purpose of this JAG grant is to fund the purchase of specialized equipment, radio technology upgrades, and vehicle purchases to support patrol and criminal investigation operations in these jurisdictions.  Some of this equipment will be use
The City of Albuquerque Police Department and the County of Bernalillo Sheriff’s Department (BCSO) are submitting a joint application as required by the Disparate Certification.  The Albuquerque Police Department (APD) will serve as the admin
City: 09 JAG Law Enforcement Request / APD         County: 09 JAG Law Enforcement Request / BCSO
The city of Naperville and DuPage County, as disparate jurisdictions, will share this Recovery Act JAG award. The city of Naperville will serve as the fiscal agent and use their share of the funds ($41,626.50) to purchase electronics and variou
Purchase of emergency vehicles and equipment
Operation Safe Tiger:  MHHS SRO Program.  The Mountain Home Police Department intends on improving the overall safety and welfare of individuals on the campus of the Mountain Home High School by employing community oriented and problem solving
cOMPUTER SOFTWARE EQUIPMENT PURCHASED FOR MANDATORY ENCRIPTION REQUIRED. OTHER SOFTWARE EQUIPMENT TO ALLOW FOR MOBILE UPDATES FOR SWORN POLICE OFFICERS.
K-9 Unit with vehicle, equipment, and firearms
The City of Athens will use the Recovery Act JAG funds to purchase equipment that will improve the radio communication system of the city police department.  The equipment will be utilized to make technological improvements and enhance the deli
Printer mounts for mobile data terminals were also be purchased to access information from other agencies to help identify subjects for warrants and other offenses.  Specific training will be scheduled to enhance officers' skills in combating c
LPD Violent Crimes and Criminal Apprehension
Stark County has used the funding received to purchase 2010 Ford Crown Vic cruisers and necessary equipment.  These purchases are complete.  These vehicles have replaced unsafe and costly repaired fleet., and at the same time increased officer
Thornton's Proactive Community Crime Reduction Initiative
Seneca Police Department Equipment Project
Law enforcement initiatives to reduce the impact of drugs and violent crime and enhance public safety in Dane County through the purchase of equipment and services which otherwise would be unfunded.
The city of Ogden, serving as the fiscal agent for this award, will share the Recovery Act JAG funds with the cities of South Ogden, Roy, Riverdale, Harrisville, Washington Terrace and the county of Weber.  Some of the types of projects are pur
Ogden City Joint Recovery Act JAG Project
The Lake Havasu City Police Department implemented the E-Ticketing Project, which involves the use of a handheld device that can scan a driver's license, read the bar code of a vehicle registration, populate the location from GPS coordinates, a
The City of Blackfoot will use their Recovery Act JAG award to purchase law enforcement equipment adn supplies for the Blackfoot Police Department
Improve the function of the Criminal Justice System
The cities of Columbus and Eagle Lake and Colorado County are disparate jurisdictions.  The three jurisdictions will share the Recovery Act JAG award.  The city of Columbus will serve as the fiscal agent for the grant award.  Colorado County an
Monies used for the funding of three police officers.  These full time officers' salaries funded through this grant would continue the spirit of the Malden Police Department mission to serve the public.
Malden Police JAG 2010 Police Salary Grant
City of Owensboro and Daviess County 911 Dispatch Center Project
The City of Post Falls Police Department plans on purchasing two (2)new patrol cars and the equipment to outfit said vehicles.  The car computers and wireless sytems for the patrol cars will allow the officers a faster response time as they wil
Post Falls Police Department Equipment Purchase
FY09 Recovery Act JAG Program.  This 88K will allow the purchase of in car camera sustems for the PD along with 2 tasers.  As well it will provide funding for the purchase of a In car radios plus the cost of installing the radios for the Oktibb
Purchase of Digital In-Car Cameras for patrol and traffic vehicles
The City of Alexandria will use the Recovery Act JAG funds for several law enforcement and courts-related purposes and programs.  The Alexandria Police Department will obtain equipment needed to improve tactical, crime analysis, and crime scene
Enhancing Public Safety through Public Safety, Court Security, and Youth Programs
Botetourt County Recovery Act JAG project.  Upgrade to in car camera systems through the purchase of four digital in car camera systems.
Botetourt County Recovery Act JAG project
The Forensic Social Worker (FSW) performs their duties at the Orange County Jail through Corrections Health Services Division.  This grant position is an integral part of the Jail Diversion staff.  The FSW position works with mentally ill inmat
Forensic Social Worker for Corrections Dept./Radio purchases for Sheriff's Office
Communication Technology Upgrade -  a)  Asset Forfeiture Training b)  MDT Computers c)  Viper Radios
Combating Domestic Violence against Women
FY 09 Recovery Act Edward Bryne Memorial Justice Assistance Grant Program Local Solicitation. Clovis/Curry County CAD & RMS Upgrade.  This project will promote interoperability and enhance regional communications.  The Clovis Police Department
The overall purpose of this grant program is to enhance the effectiveness of the local criminal justice systems and to contribute to the economic recovery effort through the acquisition of additional law enforcement equipment technology (prime
Grant funds will be used to purchase a Digital Imaging Mangement System (DIMS) which will allow the Sheriff's Office to have an evidence chain of custody.  The DIMS System allows images to be stored on a central system where they are protected
The disparate jurisdictions consisting of the City of Huntington and Cabell County will use their Fiscal Year 2009 Recovery Act JAG award in the amount of $562,398 to support personnel, overtime, and equipment purchases.  The City of Huntington
BJA FY 09 Recovery Act Edward Byrne Memorial Justice Assistance grant Program Local Solicitation
Patrol and Special Response Equipment Enhancement Program
Edward Byrne Memorial Justice Assistance Grant Program for Local Solicitation used for technology upgrades in the Accomack County, VA Sheriff's Office.
Park County will use its Fiscal Year 2009 Recovery Act JAG award in the amount of $58581 to purchase two standard package patrol vehicles.  In addition, training for rural law enforcement will be provided to enhance law enforcement knowledge of
Selinsgrove Borough and Snyder County will be using their 2009 JAG Recovery fund to support the hiring of the 6th COPS program patrol officer for the Borough of Selinsgrove.  This will include uniforms, gear, weapons, and radios.  In addition,
Local Enforcement Combatting Local Crime - This award provides desparate jurisdictions in Lake County Indiana with funds to advance local law enforcement goals with technology.  The items listed for purchase are not available to the municipal d
Equipment enhancement to support operational needs by purchasing police cars, CCTV equipment, key tracking system, upgrades to computer data storage system and EOC equipment purchases.
EXPANSION AND CONTINUED OPERATIONS OF THE ST MARY PARISH MULT-JURISDICTIONAL TASK FORCE
EXPANSION AND CONTINUED OPERATIONS OF THE MULTI-JURISDICTIONAL TASK FORCE
St. Augustine Police Department Equipment Improvement Program
The JAG Program provides states, tribes, and local governments with critical funding necessary to support a range of program areas including law enforcement, prosecution and court, prevention and education, corrections and community corrections
The Henry County Police Department project entitled 'Training, Retention, Expansion, and & Education' or 'T.R.E.E.' was awarded a grant of $95,993.00 under the Edward Byrne Memorial Justice Assistance Grant (JAG) Formula Program: Local Solicita
Training, Retention, Expansion, and & Education or T.R.E.E.
To provide subsidized, part-time, community service work-based training for low-income persons age 55 or older who have poor employment prospects.  It is intended that these community service experiences serve as a bridge to other employment po
Senior Community Service Employment Program (SCSEP)
The purpose of the Senior The purpose of the Senior Community Service Employment Program (SCSEP) is to provide part-time (20 hours per week) work experience for low-income individuals age 55 and older.   The work experience assignments provide
RECOVERY ACT-OLDER AMERICANS-OTHER NATIONAL SPONSOR
To provide subsidized, parttime, community service work-based training for low income persons aged 55 or older.
Senior Community Service Employment Program.
Quartz-Cottonwood Road Design. Requisition to DJ&A to include site visit, survey and design of the Quartz-Cottonwood Road system involving portions of Roads 416, 334, and 239.  The existing roadway is a narrow single lane loop road with three p
Thinning and Handpiling on the Crooked River National Grasslands for a total of 1939 Acres. Wildfire and Hazardous Fuels Reduction.
Painting Interior and Exterior alter. misc. maintenance bldg
slash, pile, thin, burn silvicultrue units in Waters Cr. by cutting down trees and brush that no one wants and then piling it by hand and then lighting it on fire with gas, diesel and matches
Manual handpiling in the Bend Fort Rock Ranger District (Myst Units)
AARA DES NF, BFR IDIQ THINNING. HAND THINNING & BUCKING & LOPPING
Inspection Services for Road Maintenance Projects in New Mexico--part of USFS EROC-SW
Other Support Activities for Road Transportation
Acquisition Support Services to support USFS Vallejo, CA EROC-SW.  Original award was 1,769,208.00 but subsequent funding mods have increased it to $3,501,208.
The purpose of this procurement is to obtain the services of a broadband industry consultant to implement the statutory requirements of the American Recovery Act and Reinvestment Act of 2009 (the Recovery Act) § 6001, Pub. L. No. 111-5, 123 St
DELTA ENGINEERS, ARCHITECTS, & LAND SURVEYORS, P.C.
Bid Phase and Construction Administration Services for the Replacement of a Chiller, Generator, and UST at the HNRCA in Boston, MA.
Contractor shall install a new HVAC system and exhaust for fume hood and all necessary controls.  Installing insulation above the ceiling and underside of roof decking.  Installing ceiling system and light fixtures.
Surveying, posting, marking, and painting of US Forest Service boundary lines.
Repaving Cascades Parking Lot on the George Washington/Jefferson National Forest
Replace bridge on Forest Service road 112A, HRD, National Forest in Mississippi.
Road 112A, Milepost 1.40, Homochitto National Forrest
Road Maintenance IDIQ,provide road grading, brushing,place gravel and clean ditches.
PAOLI EXPERIMENTAL FOREST ROAD MAINTENANCE PROJECT AT HOOSIER NATIONAL FOREST.
Furnish, deliver and install 23 precast concrete toilet buildings in the Mark Twain National Forest.
Manufacture, deliver and install 2 prefabricated, precast concrete restroom buildings in the Mark Twain National Forest.
Other Crushed and Broken Stone Mining and Quarrying
Baldwin RD Idlewild Fuels Cadastral Survey
Wayne National Forest Ironton District Non Native Invasive Species reduction project (clearing forest fire fuels)
Equipment & materials for reconstruction of Hoyer Campground Roadways
Ft. Collins, CO Replace NCGRP Light Fixtures
Recovery Roof Replacements to Auto Shop, Echo Summit Chalet and Fire Cache in the Eldorado National Forest
Highway improvements along John Neff Drain # 390.
The dimorphic fungus Histoplasma capsulatum var. capsulatum [Hc] is the most prevalent cause of fungal respiratory infections.  Hc infects approximately 500,000 individuals in the USA each year.  Infection usually results in a mild, often asymp
Coxiella burnetii is an obligate intracellular gram-negative bacterium that causes the worldwide zoonotic disease, Q fever. Natural human infections commonly occur via inhalation of infectious aerosols, manifest clinically as atypical pneumonia
The Role of Antibody-Mediated Protective Immunity Against Q Fever
DESCRIPTION (provided by applicant): Asthma has been increasing in prevalence and severity for unknown reasons. Though our understanding of the pathophysiology remains poor, it is widely accepted that asthma is an inflammatory disease and CD4+
Posttranscriptional Gene Regulation in Asthma
Yersinia pestis translocate virulence factors from the bacterial cytoplasm into host immune cells during infections through the Type III Secretion System (TTSS). This system allows for rapid activation of injection of Yops, proteins that go on
Regulation of Yersenia pestis virulence genes in response to host cell contact.
U.S. Agency for International Development
SYSTEMS RESEARCH AND APPLICATIONS CORPORATION
The scope of this work is to complete the GLAAS Development and Mainteance work to enable full deployment of the system as outlined in the GLAAS Integrated Baseline Review (IBR) and SRA Work Breakdown Structure (WBS), and provide GLAAS Tier-3 s
Reconstruction of Runway 12-30 at the Las Cruces International Airport.  The runway is 7499 feel long and 100 feet wide and is in poor condition with significant rutting and pavement failure.  It will be completely reconstructed, including remo
Invest in public transportatin throughout the state.
9 units of the VERNON COURTS (AL084000010) public housing development are being rehabilitated.
REGIONAL HOUSING AUTHORITY OF LAWRENCE CULLMAN AND MORGAN COUNTIES
Replace outdated HVAC units to more energy efficient HVAC units in 126 low income apartments.
The Capital Fund Recovery Act funds were used as follows:  188 apartments in Riverview Court received new roofs with several vacants having extensive modernization including plumbing and electrical upgrades, central heating and air, new kitchen
Public Housing Capital Fund Recovery Act
HOUSING AUTHORITY OF THE CITY OF DECATUR
The ARRA Capital Fund Grant AL09S04850109 awarded to Decatur Housing Authority will be used for roof replacements and related items at 191 public housing units located in 70 buildings at our Sterrs Homes, Sterrs Homes Addition and Westgate Gard
Conduct modernization activities at various Public Housing developments.  This funding can be expected to result in providing employment for architects and engineers, construction workers and product manufacturers.  In addition this funding can
Housing Authority of the City of Roanoke, Alabama
Unit stabilization on two buildings, replace facia and soffit, install french drain system.
Conduct modernization activities at various Public Housing developments; Perform comprehensive physical needs assessment
To renovate an elderly development consisting of 20 units.  Work will consist of re-roofing all buildings, replacing windows and replacing applliancs
modify 49 units by adding storage rooms to units.
modernization of older units, upgrade the hvac and electrical system and convert to electric hotwater heaters
New metal roofing for all buildings to better insulate the buildings and create a greener project.
Roofing, Siding, and Insulation Material Merchant Wholesalers
conduct modernization activities at various public housing developments.  Comprehensive modernization of family units at Everett and Lakeview developments; Replacement of 48 units of windows and screens; complete renovation of 48 units of bathr
Comprehensive modernization of 22 family units.  Conver-sion from Gas to Electricity with HVAC installation, energy efficient windows/screens, storm doors, roofs, ranges & refrigerators, water heaters, paint interior
Public Housing Capital Fund Stimulus Recovery Act Funding
The American Recovery and Reinvestment Act of 2009 awarded one contractors job as well as provided new bathtubs, tub surrounds and new bathroom fixtures for eight public housing apartments.
Conduct modernization activities in PHA units. This funding can be expected to result in providing  employment for architects, construction workers and product manufacturers.
HOUSING AUTHORITY OF THE BIRMINGHAM DISTRICT
Conduct Monernization activities at various PH developemnt.  This funding will allow us to replace windows, install screen doors and security screens for the windows.
Modernization of 15 family units, replace roofs, site improvement
REPLACEMENT/EXPANSION OF ROLLING STOCK, ACQUISITION OF HISTORICAL STYLED BUS SHELTER.
ARRA - (10) Replacement; (2) Expansion; equipment
Invest in public transportation by purchasing 17 new compressed natural gas buses and related tools for repair, rehabilitating a bus maintenance garage, and replacing a bus wash and vacuum cleaning system.
Purchase of 17 replacement buses. Rehabilitaion of maintenance garage. Purchase of bus washer and vacuum cleaning system. Purchase of diagnostic equipment and tools.
EPA provided IHS $614,580 of Clean Water Act Indian Set Aside funds through Interagency Agreement DW-75-95765901-0 for this project.  Project scope: This project will provide the funding to import the gravel to Kivalina and ensure sufficient fu
ALASKA NATIVE TRIBAL HEALTH CONSORTIUM, INC
This project will provide washeteria improvements and will replace flooring and floor joists in the men’s and women’s bathroom and the mop sink area as needed. The floor will be crowned and more floor drains will be installed to allow water
EPA provided IHS $2,192,530 of Clean Water Act Indian Set Aside funds through Interagency Agreement DW-75-95765901-0 for this project.  Project scope: This project will provide a new piped sewer system and closure of two in-town percolating sew
Purchase a complete portable dental operatory suite equipment and associated system components.
The Recovery Act funds will be used for projects to improve the condition, fire-life safety, energy conservation, and operational efficiency of existing Tribally operated, Indian Health Service (IHS) owned and Tribally owned healthcare faciliti
FY 2009 Alaska ARRA Maintenance and Improvement Project
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). The proposed project will investigate the coldest and driest parts of the Transantarctic Mountains (Ong Valley at Nimrod Glacier and Moraine Canyo
This award is for a pilot study on Antarctic diamictite samples from two cores in the Ross Sea area. Core samples are collected at the Antarctic Research facility at Florida State University by a graduate student and the faculty. Samples locati
Determining Middle Miocene through Pliocene Changes in Paleo-Ice Flow and Basal Ice conditions in East Antarctica through Sedimentological Analyses of Core Samples
Marine mammals of the Southern Ocean have evolved diverse life history patterns and foraging strategies to accommodate extreme fluctuations in the physical and biological environment.  In light of ongoing climate change and the dramatic shifts
Collaborative Research:  Weddell seals as autonomous sensors of the winter oceanography of the Ross Sea
Collaborative Research: Integrative Study of Marine Ice Sheet Stability and Subglacial Life Habitats - Robotic Access to Grounding-zones.
'This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).'An interdisciplinary team of researchers will focus on describing the high productivity patchiness observed in phytoplankton blooms in the mid to
Collaborative Research: Modified Circumpolar Deep Water Intrusions as an Iron Source to the Summer Ross Sea Ecosystem
The project will employ a sophisticated meteor radar at the Brazilian Antarctic station Comandante Ferraz on King George Island for a number of synergetic research efforts of high interest to the international aeronomical community. The locatio
Large- and Small-scale Dynamics and Meteor Studies in the MLT with a New-generation Meteor Radar on King George Island
This study propose to use data collected from 2008 (and ongoing) to study CIR signatures at high geomagnetic latitudes.  2008 is a period of extremely low solar activity as compared to the past few solar cycles, sllowing one to study CIRs apart
Collaborative Research:PENGUIN-A High Latitude Window to Geospace Dynamics
ENERGY GRANT HEAT AND AIR ENERGY INSTALLATION OF ENERGY EFFICIENT FURNACES AND AIRCONDITIONING WITH INSULATION TO INCREASE THE SAVING OF ENERGY
HOUSING AUTHORITY OF THE COUNTY OF SEVIER
Comprehensive modernization of units. Rehabilitation of six (6) units. Replace toilets with economy friendly toilets. Replace old hot water heaters. Landscaping. Concrete driveway. Install new exterior doors. Remodel bathrooms.
Window replacement Roof replacement Sewer line replacement Remodel bathrooms
ARRA grant for modernization of low rent properties at Mount Ida, AR Housing Authority
Conduct Modernization activities at various Public Housing developments. Provides employment funding for Architect, cabinets Installer, AC installer and product manufacturers and install storm doors.
This is sewer expansion project to service the remaining homes within the city limits. Appox 70 plus homes
Purchase of Early Warning System and Fire Brush Truck
2009 Purchase of Early Warning System and Fire Brush Truck
Fire support appartus for the Huntsville Volunteer Fire Department
Community Facility Grant of $50,000.00 to City of Huntsville to purchase Fire Truck
Ozark Health seeks funding from the United States Department of Agriculture Rural Facilities Program to purchase needed Cardiac Support and Medical Cardiac Telemetry Equipment that is essential to the day to day operations of our facility from
A three-year interdisciplinary research program will be undertaken at Cape Espenberg, located on the northern coast of the Seward Peninsula (Alaska), with a focus on the history of human settlement and response to climate change between AD 800
IPY: Human Response to Climate Change at Cape Espenberg AD 800-1400
This award supports the continued development of the Exchange for Local Observations and Knowledge of the Arctic (ELOKA). It provides data management and user support to facilitate the collection, preservation, exchange, and use of local observ
ELOKA Phase II:  Toward Operational Data Management Support for Community-Based Observations Contributing to the Arctic Observation Network
On March 24, 1989, the tanker vessel Exxon Valdez ran aground on Bligh Reef, a well-marked navigational hazard in the Valdez Arm of Prince William Sound (PWS), Alaska spilling 11 million gallons of crude oil into the surrounding ecosytem. In va
Collaborative Research: To Investigate and Document Social Impacts of High-Stakes Litigation Resolution in a Renewable Resource Community
This award will support the continued implementation of the Bering Sea Sub Network (BSSN), a regional initiative of community-based organizations in Western Alaska and Northeast Russia.  The 'Intellectual Merit' of BSSN lies in its operation as
Bering Sea Sub Network:  A Distributed Human Sensor Array to Detect Arctic Environmental Change
AON: Continuing the Beaufort Gyre Observing System to Document and Enhance Understanding Environmental Change in the Arctic
RFCUNY - JOHN JAY COLLEGE OF CRIMINAL JUSTICE
This project includes 30 months of interdisciplinary research aimed at understanding how people in Arctic Communities form social connections in response to high levels of social change. The research will take place in the communities of Nain a
A Comparison of Informal Networks in Two Labrador Communities
A three year study is proposed to reconstruct the Holocene Paleomagnetic records of the Arctic and investigate linkages with regional climate using lake core studies.  At present, there are no terrestrial Arctic paleomagnetic data to the west o
Collaborative Research: The Holocene paleomagnetic record of the Arctic
Collaborative Research: A Winter Expedition to Explore the Biological and Physical Conditions of the Bering, Chukchi and Southern Beaufort Seas
This study will look at the relationships between the planktonic food web of the Barents Sea and changing sea-ice conditiions.  It will focus on the role of microzooplankton (MZP), which have been suggested to be more important herbivores than
Impacts of Climate Change and Ice Conditions on Microbial Food Web Dynamics in the Barents Sea
ARRA - TRANS-NSF RECOVERY ACT RESEARCH SUPPORT
Improving Surface Mass Balance Estimation of the Greenland Ice Sheet Through  Assimilation of Multi-sensor Satellite Products and Ground Measurements into a Regional Climate Model
Using pollen to assess local environmental variation during the viking age
Using pollen to assess local environmental variation during the viking age in skagafjordur
J STREET-HWY. 326 (RUSSELLVILLE) (REHAB)
SHADY GROVE RD-NO. OF HWY 270 (HOT SPRINGS)
Alcohol abuse is one of the most common cause of liver fibrosis/cirrhosis in western developed countries. Alcoholic liver fibrosis is caused by the excessive accumulation of extracellular matrix (ECM) in the liver. Type I collagen is the major
Treating Alcoholic Liver Fibrosis by Reversal of Type I Collagen
Lincoln Park High Rise Flooring Replacement Project
Firm fixed price for cheese manufacturing
This grant distributes money to eligible aquaculture producers that suffered financial losses associated with high feed inputs during 2008.  This may be done in one of two ways:  1)  Provide cash payments directly to eligible aquaculture produc
Postdoctoral Program in theoretical and observational astrophysics
Funding was p[rovided for the acqusition of law enforcement equipment including vehicels, ballistics shields, investigations equipment, and id card development system
2009 Law Enforcement Enhancement Program
Washington County will use these funds to fund 3 positions (2.5 FTE) within the criminal justice system.
Washington County Public Safety Collaboration
WARRICK COUNTY SRO/TECHNOLOGY UPGRADE/CRIMINAL INTERDICTION
This award was made pursuant to the FY09 Recovery Act Edward Byrne Memorial Justice Assistance Grant, Local Solicitation.  This disparate jurisdiction elected to fund projects within the program's Law Enforcement purpose area.  The overall outc
Jeffersonville-Clarksville-Clark County Law Enforcement Equipment Upgrade and Enhancement
This grant will be used to streamline the law enforcement records system for all police departments in Stearns County as well as the Sheriff.  This will complete a centralized records system that all jurisdictions can use for records.  The syst
Metro Stearns Joint Law Enforcement Server Project
Purchase forensic video enhancement equipment and attend training on equipment
The disparate jurisdictions consisting of Sedgwick County, the City of Wichita, the City of Derby, the City of Haysville and the City of Park City will share these grant funds as stated in the Interlocal Agreement with Sedgwick County handling
Justice Equipment Acquisition and Safe& Secure Communities Project
Providing up-to-date technology and equipment for law enforcement officers at Valparaiso Police Department, Portage Police Department, and Porter County Sheriff's Office in Valparaiso, Indiana
Upgrading Technology for Porter County, Indiana, law enforcement officers
The Adams County Sheriff?s Office, on behalf of Adams County, requested JAG monies to support multiple projects within the agency as well as two multi-jurisdictional task forces in which this agency is involved.   With current budget constraint
The City of Suffolk will apply Recovery Act JAG funds towards a multi-faceted approach of improving the criminal justice capacities of the city to purchase tactical equipment, computer software and other equipment for the police department. The
The Edward Byrne Memorial Justice Assistance Grant (JAG) application is a cooperative effort by The Lawrence Kansas Police Department, The Douglas County Sheriff?s Department, and the Eudora Kansas Police Department. Although the grant is being
The Collier County Sheriff's Office Overtime Program is expected to result in overtime (OT) hours which is the equivalent of 4.865 FTEs over the course of this ARRA grant.
Collier County Sheriff's Office Overtime Program
2009 Recovery Act Edward Byrne Memorial Justice Assistance Grant Program Local Solicitation allows states and local governments to support a broad range of activities to prevent and control crime and to improve the criminal justice system.
Coffeyville PD PSAP (911 Equipment) Upgrade & Independence PD Undercover/Surveillance Vehicle
Funds will be used to purchase advanced crime scene technology, an interactive white board, personnel training, software and hardware for server upgrades, and in-cruiser audio/video hardware and software.
Equipment Acquisition and Service Enhancement
Bureau of Justice Assistance FY09 Recovery Act Edward Bryne Memorial Justice Assistance Grant Program Local
Gettysburg and Littlestown Boroughs Joint Recovery Act JAG Project
Funding assistance has been and will continue to be used to purchase vital equipment needed to provide efficient and effective police service.
New Patrol Vehicles for DeKalb County Sheriff's Office
BJA FY 09 Recovery Act Edward Byrne Menorial Justice Assistance Grant Program Local Solicitation - These funds are to provide the following:   Criminal Investigations Unit - Soundproof and technology upgrades for three interview rooms; Funds fo
Community Bike Patrol And New Technologies
Laptop Computers for patrol cars project
THREE AGENCIES AGREE TO CONTRIBUTE 20% OF THE FUNDING TO THE LEE CO. NARCOTICS TASK FORCE; EACH AGENCY PLANS THE PURCHASE OF A POLICE CRUISER; KPD PLANS TO INITIATE A FORENSIC COMPUTER EXAMINER PROGRAM; TACTICAL WEAPONS TRAINING PROGRAM; UPDATE
FY 2009 RECOVERY ACT JUSTIC ASSISTANCE GRANT PROGRAM
With the Byrne/JAG money allocated to the Johnston RI Police Department, we plan to immediately deploy these funds within ninety (90) of receipt from the Federal Government.  The goal of this program is to further outfit our officers with the t
The Johnston Police Department ARRA Fund Deployment Program
Circuit Attorney Drug Crimes Task Force - To concentrate prosecutorial efforts on chronic drug users, sellers and crimes associated with drug houses; Archival Records System - $38,000:  to archive required records for compliance with state stat
City of Saint Louis Recovery Act JAG Project
The Cape Girardeau Police Department will use a portion of the funds for directed enforcement patrols to combat criminal behaviors in targeted neighborhoods, thereby enhancing the quality of life of residents and reducing criminal activity. Off
The Recovery Act Edward Byrne Memorial Justice Assistance Grant
Monroe County will use the Recovery Act JAG funds to assist the Monroe County Sheriff?s Office with overtime to provide law enforcement patrols in the neighborhoods and subdivisions of the county and re-establish its drug interdiction program o
The BJA FY 09 Recovery Act Edward Byrne Memorial Justice Assistance Grant Program Local Solicitation grant funds will be used to initiate a polygraph program, purchase covert equipment and flashlights. The cost of the polygraph program will be
The Anderson Police Department and the Madison County Sheriff's Department are disparate units of government working collaboratively to reduce crime and crime related problems in Anderson, Madison County, Indiana.  The goal of this project is t
BJA FY 2009 Recovery Act Edward Byrne Memorial Justice Assistance Grant Program Local Solicitation / Recovery Act JAG Program
Equipment grant to provide equipment for five (5) new police patrol vehicles.
The Recovery Act: Edward Byrne Memorial Justice Assistance Grant Formula Program provides funding directly to law enforcement agencies to support all components of the criminal justice system.  The funds provided by this grant will be used for
JAG Law Enforcement Equipment  we were looking to purchase equipment for in car video systems and interview recording system.  we were able to get both pieces of equipment, with the use of these pieces of equipment to record incidents that happ
BJA FY 09 Recovery Act Edward Byrne Memorial Justice Assistance Grant Program Local Soliciation
The ARRA Edward Byrne Memorial Justice Assistance Grant Program will be used to support the Leon County Enhanced Pre-Trial/Probation Monitoring, the Juvenile Assessment Center, and the purchase of Law Enforcement Equipment.
Police Patrol Rifle Program. A  program to allow for the arming  of uniformed patrol officers with  AR-15 style rifles to assist in  officers response to violent  encounters. K9 Service Dog  Program A program to allow for  the purchase and trai
Police Patrol Rifle/Police K9 Service Dog Program
BJA FY 09 Recovery Act Edward Byrne Memorial Justice Assistance Grant Program Local Solicitation  Project A - Contra Costa County:  $299,535 Outcome:  Job preservation  Project B - Antioch City: $328,062 Outcome:  Job retention   Project C - Br
The Gainesville Police Department has received $448,816 from the Edward Byrne Memorial Justice Assistance Grant (JAG) Program - Formula Program.  This funding will allow the department to support a broad range of activities to prevent and contr
City of Gainesville, FL Law Enforcement, Crime Prevention and Technology Enhancement Project
IT improvements for outdated computer systems, software and equipment.
Purchase necessary law enforcement equipment & training such as cruisers, restraints and tasers.
Strafford County Justice Assistance Grant Project
Purchase two (2) patrol cars to replace aging cars in current fleet.
Beaufort COunty Emergency Management Department will utilize all authorized grant funds in the amount of $314,777 for the procurement of police cruisers, DNA Extraction Work Stations and monitors with wall mounts to support local law enforcment
Recovery Act Justice Assistance Grant funds support all components of the criminal justice system. The disparate jurisdictions consisting of Cass Sheriff's Office and the Fargo and West Fargo Police Departments will use funds for proactive crim
The county of Caroline will use its Fiscal Year 2009 Recovery Act JAG award in the amount of $59,867 to support a new records management system and training for the sheriff's office.  The main function of the system is to complete reports and r
The City of Ukiah, along with the Ukiah Police Department, will utilize the 2009 Recovery Act AJG award to hire and train a non-sworn Community Service Officer (CSO) to support their sworn Peace Officers.
Escambia County will use the Recovery Act JAG funds across multiple agencies to ensure that maximum coordination and benefits are achieved. Specifically, funds will support a gang state attorney, jail mental health case management, gang law enf
Recovery Act/JAG Program.   Computer Aided Dispatch, Records Management System, Mobile Computing Solution, and Field Based Reporting in support of efficient delivery of law enforcement services.  Key/major deliverables are: 1) procurement; 2) i
Planning, evaluation and technology improvement program. Computer Aided Dispatch, Records Management System, Mobile Computing Solution and Field Based Reporting.
Pickaway County will apply Recovery Act JAG funding towards essential equipment aimed at enhancing law enforcement services provided to the community.  Specifically, the county Sheriff's Office will purchase less-than-lethal weapons in an effor
TO IMPROVE OR ENHANCE THE SHARING OF CRIMINAL JUSTICE INFORMATION ACROSS RURAL LAW ENFORCEMENT AGENCIES AND OTHER CRIMINAL JUSTICE COMPONENTS.
FY 2009 RECOVER ACT JUSTICE ASSISTANCE GRANT PROGRAM
Keeping Offfiers fighting Drugs and the crimes they cause.
Funding from the grant allows the Bossier City Police Department to provide over-time money to officers working on the DWI Task Force, Armed Robbery Task Force, and the Community Oriented Policing Walking Patrol.  This grant also provides fundi
JAG Overtime Enforcement and Equipment Purchase
Upgrade computer-aid dispatcher and upgrade the computer server.
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). This award will establish a new Research Experiences for Undergraduates (REU) Site at the University of Arkansas. Ten REU students work with facul
REU site: Interdisciplinary Research Experiences in the Astronomical, Space and Planetary Sciences
Dr. Michal Simon and students will undertake a project to explore the formation of single and binary stars. The research will provide theorists with precisely measured masses of young stars to enable critical tests of theoretical calculations o
ARRA: Astrophysics of Single and Binary Star Formation
Intellectual Merit: The question, Who are our neighbors? is addressed from many different angles by this proposal, focusing on discovering and characterizing the fainter members of the solar neighborhood — red dwarfs, white dwarfs, brown dwar
Fundamental Stellar Parameters from the CHARA Array
UNIVERSITY OF NORTH CAROLINA AT ASHEVILLE
This project employs time-intensive radio astronomical observations to study rapidly varying phenomena.  The Dedicated Interferometer for Rapid Variability (DIRV) at the Pisgah Astronomical Research Institute (PARI) will be used to observe intr
RUI: A Muli-University Study fo Rapid Variations and Transient Events at Radio Frequencies
University of North Carolina at Asheville
Intellectual Merit: Silicate dust plays an essential role in many astrophysical environments. The 'amorphous' silicate spectral features have been observed in our solar system, young stellar objects, star formation regions, novae, and the diffu
Collaborative Research:  An integrated experimental and observational study of cosmic silicate astromineralogy
Through this award, Dr. Pascucci, along with students and collaborators, will complete an on-going ground-based campaign to spectrally resolve bright gas emission lines detected with the Spitzer Space Telescope toward many protoplanetary disks.
Water Transport and Dispersal of Gas in Protoplanetary Disks
The project is designed to support for development of major research instrumentation: CHIRON (CTIO High Resolution Spectrometer.)
ARRA: MRI Development of Chiron:  CTIO (Cerro Tololo Inter-American Observatory) High Resolution Spectrometer
A major objective of the Geospace Environment Modeling (GEM) Focus Group on Space Radiation Climatology is to investigate the relationships between interplanetary conditions and trapped radiation belt particles and how these relationships chang
GEM:  Phase Space Density Gradient of Energetic Electrons at Geosynchronous Orbit During Sharp Solar Wind Pressure Enhancements
This project aims to better delineate the global manifestations of non-migrating tides from the stratosphere through the thermosphere and to better determine the origin of the non-migrating tides which is largely in the troposphere. The investi
Atmospheric Tides and Their Effects on Ionosphere-Thermosphere-Mesosphere (ITM) Dynamics, Composition, and Structure
Magnetohydrodynamic Modeling of Current Sheet Structure and Magnetic Reconnection Using a Realistic Description of Transport Processes
REU Program in Solar Physics. The students' main activity is carrying out individual research projects in Solar Physics under the supervision of CFA staff scientist for ten weeks during the summer. Most of the projects involve the analysis of d
Solar Physics at the Harvard-Smithsonian Center for Astrophysics
RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK
RECOVERY ACT RESEARCH Experience for undergratduates collaborating with the Goddard Institute for Space Studies Center for Global Climate Research
REU Site:  The City University of New York/Goddard Institute for Space Studies Center for Global Climate Research
Further development of solid phase microextraction (SPME) techniques for the successful sampling and analysis of biogenic sesquiterpenes (SQTs) emitted from vegetation.  The key result of the work will be published data describing emissions of
RUI:  Application of Solid Phase Microextraction to Determine Emission Rates of Sesquiterpenes from Terrestrial Vegetation
The objective of this proposal is to strengthen our understanding of the atmospheric chemistry of nitrous acid (HONO) and nitric acid (HNO3) in forested environments. Understanding the behavior of atmospheric HONO and HNO3 is very important for
MEASUREMENTS OF NITROUS ACID AND NITRIC ACID DURING BEARPEX2009
This University of New Hampshire team has recently developed a fully automated version of a popular and familiar shock analysis code, based on the solution of the Rankine-Hugoniot relations, creating a tool that is accessible via the internet.
NSWP: Automated Shock Analysis for Space Weather Predictions
3-year research project will test the ability of a high performance aerosol lidar to measure the wind in the lower atmosphere. The project will also evaluate the usefulness of the lidar in frontiers in microscale atmospheric research. If shown
Study of the evolution of coronal magnetic configuration and the corresponding free magnetic energy is the key to understanding and forecasting solar explosive phenomena such as flares and coronal mass ejections (CMEs). We propose a 3-year prog
Three-Dimensional Magnetic Configuration and Evolution of Flare Productive Active Regions
This award is a collaboration between SIUC and the Storm Peak Laboratory. It supports gas samples collected in western Colorado forests that have been infested with the mountain pine beetle.  Forest emit volatile organic compounds (VOCs) that r
Collaborative Research: RAPID--Investigating Potential Secondary Organic Aerosol (SOA)
'•The Low Level Underwater Multispectral Imaging System (LUMIS) design was finalized by Marine Physical Lab (MPL) personnel at the Scripps Institution of Oceanography and fabrication was begun. After testing, more powerful fluorescence strobe
Computer Vision Coral Ecology: Cyber-Enabled Image Classification for Rapid, Large Scale, Automated Monitoring of Climate Change Impacts on Coral Reefs
The Yuma County Housing Department is implementing the following activities using Capital Fund Recovery Act funding: 102 units of the MOCTEZUMA (AZ013000001) public housing development are being rehabilitated.
Safety Upgrade Replacement of Bridge Guiderail End Treatments at 82 Bridges, Ocean County.
Federal projects B091008 and ARSCT-B091A01 combined, involving contract patching and  miscellaneous work at various locations in Transportation District 1 in Albany and Laramie counties.
The Community Development Block Grant Recovery Act (CDBG-R) program enables local governments to undertake a wide range of activities intended to create suitable living environments, provide decent affordable housing and create economic opportu
State Community Development Block Grant Recovery (CDBG-R)- Owner Occupied Housing Rehabilitation and Community Infrastructure
HOUSING & COMMUNITY DEVELOPMENT, CALIFORNIA DEPARTMENT OF
To fund housing activities, public improvements, public facilities projects, as well as business expansion serving lower-income people.  In selecting projects to be funded, priority was given to projects that can award contracts based on bids w
Community Development Block Grant - Recovery Program
ECONOMIC AND COMMUNITY DEVELOPMENT, CONNECTICUT DEPARTMENT OF
The State of Connecticut has awarded six municipalities with grants that will cover activities from infrastructure - including streets and sidewalks, demolition of properties to construct new housing, and neighborhood stabilization activities.
Sidewalks & Street Improvements in Naugatuck, Plainfield, Torrington, Wallingford and Windsor.  Housing Acquisition & Improvements in Enfield & Windsor.
The Community Development Block Grant Recovery (CDBG-R) program funds will invest in energy-efficient housing rehabilitation.
The Department of Housing and Urban Development (HUD) awarded the State of Georgia $10,866,994 on August 14, 2009 for the purpose of making awards to local governments in order to allow them to carry out local community and economic development
Community Development Block Grants/State's Program and Non-Entitlement Grants in Hawaii - (Recovery Act Funded) (Note that HUD has designated this as the CDBG-R program.)
Community Development Block Grant Recovery (CDBG-R) Funds Authorized Under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5, February 17, 2009).  The purpose of the award is to carry out, on an expedited basis, eligible comm
Community Development Block Grant Recovery (CDBG-R) Funds
The CDBG program enables local governments to undertake a wide range of activities intended to create suitable living environments, provide decent affordable housing, and create economic opportunities primarily for low- and moderate-income pers
FINANCE & ADMINISTRATION, NEW MEXICO DEPARTMENT OF
The purpose of the Community Development Block Grant Program (CDBG-R) is to improve the quality of infrastructure for the benefit of areas of low to moderate income. The State of New Mexico funded 8 communities with CDBG-R funds in which 70.7%
Community Development Block Grant Program
407 Galisteo St. Bataan Memorial Bldg #202
Community Development Block Grant Recovery (CDBG-R) Program funds are to be used to stimulate the economy through measures that modernize the Nation’s infrastructure, improve energy efficiency, and expand educational opportunities and access
Community Development Block Grant funds are used to enhance public systems through the investment of federal and state resources.  Commerce provides the support needed by communities to enhance infrastructure, facilities, and conduct the strate
Community Development Block Grant/States program and Non-Entitlement Grants in Hawaii (Recovery Act Funded)
The County of Hawaii's Office of Housing and Community Development (OHCD) was award CDBG-R funds to stimulate the economy through infrastructure activities that provide basic services to residents or activities that promote energy efficiency an
Kamuela Elderly Housing - Solar Water Heating System and Hospice of Hilo - In-Patient Facility Site Improvements
The Community Development Block Program Recovery (CDBG-R) funds are investing in the rehabilitation of two public facilities: Maui Food Bank and the Easter Seals Hawaii Facility in the J Walter Cameron Center. The purpose of these projects is t
Renovation and restoration of the Project Pay Building in Historic Zinn Park located at the intersection of Moore Avenue and 13th Street.
Renovation and Restoration of Project Pay Building
Community Development drainage and street improvements
The City of Opelika plans on utilizing its $68,431 in CDBG-R funding for two activity: Curb and Gutter installation and Emergency Home Repair. Of this amount, $67,821 has been spent. The curb & gutter program has used $7,890 to construct 160 LF
Between Alabama Ave. to 1904 S. Long St.
The City of Mesa has given priority to the East Valley Mens' Center rehabilitation project.  This project will rehab the shelter that serves hundreds of homeless men each year. The project consists of three phases: Renovation of the freestandin
East Valley Men's Center Rehabilitation - Shelter for homeless men
Community Development Block Grant (CDBG-R). In the current Consolidated Plan one of the highest priorities was to improve housing conditions for low and moderate income people. These funds will be used for the City's Housing Rehabilitation Prog
Community Development Block Grant Energy Conservation
CDBG-R Public Facilities and Improvements (Traffic Signal Upgrade Project)
The City of Alameda is partnering with the Alameda Housing Authority (AHA) to acquire and rehabilitate a 9-unit residential building in an effort to preserve the units has affordable housing stock in Alameda.  The AHA intends to make the units
(1)Expansion of Trower Neighborhood Center;(2)Continued and expanded code compliance related rehabilitation activities and (3) Planning and General Administration.
Rehabilitation (Improvement and Expansion in the Supply of Affordable Housing)
1. Milpitas Food Pantry ($18,293)-Provides daily supplemental supplies of food to very low and low-income families. Approximately 1,000 Milpitas residentrs will benefit from these services.2) Support Network for Battered Women ($5,000)-Provides
CDBG-R Entitlement award. The funds will be used for owner-occupied housing rehabilitation program.
HUD?s Recovery Act funds support three themes that align with the broader goals of the Recovery Act: (1) promoting energy efficiency and creating green jobs, (2) unlocking the credit markets and supporting shovel-ready projects, and (3) mitigat
Horn Road ADA Accessibility Improvements
Reconstruction of two alleyways, renovate 104 wheelchair ramps and construction of 8 new wheelchair ramps.
Renovation of two alleyways, reconstruction of 104 wheelchair ramps and construction of 8 new whweelchair ramps
CDBG-R funds will be used for the Water Service Improvement project which will replace substandard water lines and meters in low and moderate income areas.  Also, CDBG-R funds will be used for the Administration of the program.
Community Development Block Grant Recovery Act (CDBG-R) program funds will invest in the following projects for public improvements and job training and placement activities: 1) East Garfield Neighborhood Revitalization, 800 S. Maryland Ave., 2
Glendale, CA CDBG-R Program  1. E. Garfield Neighborhood Revitalization public improvements, 2. New Horizons Child Car Development Center, 3. Youth Employment and Training Program, 4, Community Work Program, and 5. CDBG-R Administration.
CDBG ARRA activities will preserve and create jobs through acquisition of land for affordable housing, public and private development projects such as street and sidewalk improvements and financial assistance to businesses to increase job train
ARRA-Community Development Block Grant (CDBG-R)
CDBG-R SIDEWALK AND PEDESTRIAN RAMP REPLACEMENT PROJECT
Sanborn Ave. and Mulford Ave. Street Improvement Project. Part of the funds will be used for the design of the project.  The balance of funds will be used to reconstruct failed/cracked street pavement, improve street drainage, replace damaged/m
Sanborn Avenue Street Improvment Project
The award was allocated to three projects. The two of three projects have already been completed and consisted of a concrete improvement street and sidewalk infrastructure that included the replacement of 4000 square feet of substandard sidewal
CDBG-R Public Facility and Infrastructure Improvement Projects
CDBG-R funds will be used to preserve Shelter from the Storm's bilngual Ddomestic Violent & Advocacy Center in the City to provide a comprehensive range of crisis counseling & supportive services; to assist very low-income homeowners with minor
Community Development Block Grant - Recovery funds of $107,683.
Melba Street Sidewalk, Curb & Gutter Improvements
Los Serranos Infrastructure Phase 1B - Storm Drain Improvements
City of El Centro Sidwalk Program focuses on areas with non-existant sidewalks, or sidewalks in need of re-construction to make them ADA accessible.  There are currently thirteen locations on the project list with four more being investigated.
The award benifits energy efficency at a low income school, public housing, and upgrades at the Fire House serving a low income census track.
The Community Development Block Grant-Recovery Act funding will allow the City of Sarasota to provide economic development in a low- and moderate-income neighborhood, primarily along the Dr. Martin Luther King, Jr. Way corridor.  Two to three b
Port Orange Adult Activity Center Facility Improvements -Interior and exterior renovations to existing Port Orange Adult Activity Center, to include, handicap accessibility retrofit to existing restrooms, improvements to kitchen facilities, des
Port Orange Adult Activity Center Facility Improvements
Washington Avenue Streetway Improvements project, to improve pedestrian access and drainage, install street lighting, roadway improvements, landscaping and irrigation.  To improve LMI neighborhood.
Two projects within the community qualify and meet the criteria for funding under CDBG-R.  These projects provide the city with the opportunity to improve its public facilities and provide long-term economic benefits within the identified areas
Storm Drain & Pedestrian Walkway Rehabilitation
CDBG-Recovery.  City of Savannah, Georgia.  I.  MOSES JACKSON COMMUNITY CENTER.  These funds will be used to build out a portion of the Moses Jackson Community Center located in West Savannah (CT 6.01).  When construction is complete, the Cente
CDBG-R funds have a clear purpose to stimulate the economy through measures that modernize the nation?s infrastructure, improve energy efficiency, and expand educational opportunities and access to healthcare.  The City of Warner Robins plans t
2008 phase of multi-year sidewalk design and construction project in designated CDBG target areas (40.7%) on Roswell Road in Sandy Springs, GA. CDBG-R funds ($146,909) are targeted to surveying and design costs required for future sidewalk cons
Roswell Road Multiyear Sidewalk Improvement Program
Improve pedestrian ramps in LMI neighborhoods to increase ADA compliance and accessibility.
The Community Development Block Grant Recovery (CDBG-R) funds will invest in Five Mile Creek Pathway and W.8th Street Pedestrian Lighting projects. The purpose of these projects are to create/sustain jobs in construction, consulting, and govern
Five Mile Creek Pathway and W.8th Street Pedestrian Lighting
The Community Development Block Grant - Recovery Act(CDBG-R) funding was allocated to the Village's Public Works Department. The purpose of this project is to improve seven deteriorated alleys and one deteriorated street in eligible low- and mo
Village of Oak Park, Public Works Engineering CDBG-R Street and Alley Improvement Project
Telemarketing Bureaus and Other Contact Centers
The Village will use CDBG-R funds to conduct energy audits and retrofits on non-profit agencies that assist low-moderate inocme residents.  Retrofits may include the replacement of necessary appliances, repalcemnet of HVAC, roof, windows or oth
Community Development Block Grant funds to provide community development through the improvement of public facilities along the Wells Street corridor.
CDBG-R funds for the City of Terre Haute, Indiana.
Construction, Mining, and Forestry Machinery and Equipment Rental and Leasing
LAFAYETTE CITY PARISH CONSOLIDATED GOVERNMENT
ARRA, CDBG-R to be used by LCG for the purpose of overlaying or reconstructing 11 streets in the jurisdiction previously identified as needing to be addressed.
Focus on economic development with the emphasis on job creation and retention and services to disadvantaged neighborhoods.
CDBG R funds received due to our status as an entitlement community.  The funds will be used for sidewalks and LED streetlight conversions.
The award will be used to stimulate the economy by making 3 infrastructure improvements within the city of Fitchburg - and will retain full time permanent municipal positions. The Rollstone Street Sidwalk and Fence Project Phase 2 will include
City of Fitchburg, MA. CDBG-R Substantial Amendment. Activities include: Administration and Delivery Costs; Rollstone Street Sidewalk and Fence Project Phase 2; Sheldon Street Riverside Trail; and Elm Street Sidewalk and Street Resurfacing Proj
Funding was used for infrastructure and public improvement projects such as side walk repair, accessibility adaptations, street repaving and utilities connections
Rose Kennedy Lane Sidewalk and Street  Repair, Winthrop Street Accessibilt Sidewalks
Sidewalk reconstruction in low/moderate income residential areas, Dwight Street corridor and environs.
The Community Development Block Grant Program Recovery (CDBG-R) funds will invest in Pellegrini Park Accessibility Improvements and ADA Compliance, Stearns Park Accessibility Improvements and ADA Compliance, Nahanton Accessible Pathway and Hand
CDBG-R entitlement grant. Will be used for replacement of water, sewer and drainage lines under the full length of Curtis Street, in Waltham's CDBG Target Area. Low and moderate-income people comprise 52% of the population in the Curtis Street
The Community Development Block Grant Program Recovery (CDBG-R) funds will invest in the Town of Barnstable Micro-Enterprise Loan Program.  The purpose of the project is to provide assistance to income eligible entrepreneurs to facilitate econo
COMMUNITY DEVELOPMENT- US Department of Housing and Urban Development Community Development Block Grant Funding under the American Recovery and Reinvestment Act of 2009 (CDBG-R). In order to meet or exceed the expedited timeframes contemplated
Street Resurfacing & Water Main Replacement (CDBG-R)
Renovation to Human Services Building - Simmons House, HAVEN funding- Public service agency focus on domestic violence victims and their families & Administration
Community Development Block Grant - Recovery (CDBG-R) funds were used to support the following five (5) public facility/improvement projects:   Residential Street Improvements - Involves curb and gutter reconstruction and asphalt resurfacing fo
Replace deteriorated and defective sidewalks in low to moderate income areas to improve roads and pedestrian access safety and walkability for residents in eligible census tract areas.
Minneapolis 2008 Consolidated Plan Amendment #3, application for Community Development Block Grant ARRA Entitlement Grant (CDBG-R). Funds will support nine projects in the City of Minneapolis addressing Recovery Act goals. Funded projects will
Community Development Block Grant Recovery (CDBG-R) Funds Authorized and Appropriated Under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5, February 17, 2009) ? City of Minneapolis, MN
Sidewalk Construction on Independence Ave.
CDBG-R money will be used to expand three existing CDBG program administered by the City of St. Peters including a Home Improvement Loan Program, a Home Ownership Program and a Transportation Program.
All Other Transit and Ground Passenger Transportation
The Community Development Block Program Recovery (CDBG-R)funds will invest in the Administration Program, Emergency Homeless Prevention Program, and the Window Replacement Program.  The purpose of this project(s) is to assist residents on the b
Administration/Public Service Agency Assistance/Window Replacment Program
1) Center For Mental Health  - The project consists of $61,000 of CDBG-R funds for the rehabilitation of the leaking, deteriorated roof on the Center West, a former motel being rehabilitated into a transitional living center for people with sev
Great Falls Community Development Block Grant Recovery Program
Infrastructure improvements including installation of two fire hydrants in a lower-income neighborhood and repairs to a pedestrian bridge connecting two other lower-income neighborhoods. Administration.
Community Development.  LED pedestrian lights and street trees, Marix Code 03L at 2 locations:  4th Street, A to J and 10th Street, Charleston to Military.  ADA park accessibility project at Hayward Park, N. 9th and Military Road, Matrix Code 0
CDBG-R activities include 2 public infrastructure projects (LED pedestrian lights and street trees, Marix Code 03L and 1 ADA park accessibility project, Matrix Code 03F.
The CDBG-R funds allocated to the City of Las Vegas will be used to increase energy efficiency as well as create and retain jobs.  Specifically, these funds will be utilized to cover three solar covered carports that will produce electricity, t
CDBG-R: Zephyr Way Pedestrian Improvements
Public Facilities Improvements. The original scope was six (6) streets, including Park Slope between Main Avenue and Manilla, will be improved and resurfaced. An additional three (3) streets have been added as an award amendment.
Community Development Block Grant (CDBG) Recovery Act Funded
Funds used within the scope of an ongoing development to improve the streetscape and building facades along the Central Avenue business district.
Grant funds will be used to make improvements to 30th and 31st Streets. Work will include catch basins, handicapped accessible curb cuts & repaving.
1) Installation of drainage system & road reconstruction on two streets in the Cedargrove Heights neighborhood to eliminate storm water and eliminate street flooding.  This project will enhance property values and eliminate potential property d
CDBG-R funds to replace 500 linear feet and re-line 1,650 linear feet of sanitary sewer on Allenhurst Road in the Eggertsville section of the Town.
Community Development - These funds will be used for the South Street Streetscape Improvement project, in a deteriorated, low/mod area of the City's downtown. The overall project includes curbs, sidewalks, streetlighting and drainage.
water line that will eliminat leakage, thus conserving water and increasing water pressure within this neighborhood.
State Street and Big Tree Road Water Line Reconstruction
Community Development Housing Rehabilitation: Activities undertaken in this activity will particularly address issues related to energy efficiency and retrofitting existing homes with green technologies.
Single Family Rehabilitation for enregy Efficiency
Project replaced undersized drainage with a larger prefabricated culvert designed to manage stormwater flow more efficiently and reduce flooding in a target area.  Infrastructure improvement benefits a low to moderate income neighborhood.  Proj
Community Development Block Grant-Recovery funds will be used for Clearance and Demolition, Rehabilitation, Acquisition, and Planning and Administration.
Community development activities including housing rehabilitation, energy efficiency, ADA compliance and green job training.
1. City of Raleigh, Community Services Department, Youth Employment Program - $60,000. The City of Raleigh Youth Employment Program promotes Raleigh?s youth by helping them develop quality Life Skills. Youth perform public service while earning
St. Monica's Public Facility rehabilitation and Ship of Zion job readiness training - Youth Employment  Program
ARRA will be used for the North Green Street Sidewalk Project in combination with regular CDBG funds
North Green Street Sidewalk Enhancement Project
CDBG-R Funds for public facility improvements.
Kerneywood Streets Project; Day Drive Repair Program
Funding was used for the construction-rehab of the Men's Gateway Shelter and infrastructure/traffic calming improvements in the Wright-Dunbar and Oregon Business Districts.
1.  Water/sewer improvements will install new water line or sanitary sewer line in low income neighborhoods and/or for low income homeowners,  2.  Neighborhood facilities improvements to a facility used for youth/adult programs. Building is in
CDBG-R funds will be used to for a $10M mixed use development with 40 senior housing units, 13 to 15 market rate housing units and approximately 9,500 s.f. retail space on the first floor called Watermark located in low/mod census block on S. F
12-Construction of Housing & 04-Clearance and Demolition
The City of Edmond will utilize the CDBG-R funds for two activities: (A) PUBLIC INFRASTRUCTURE and (B) HOUSING REHABILITATION & WEATHERIZATION. These activities, along with a unique public/private partnership between the City of Edmond, Central
Community Development- two programs are funded.  One for homeowner repair of low/moderate income citizens and one for the rehabilitation of a low income 8-unit apartment complex.
Community Development Block Grant Entitlement, Sec 106(b)
Through the CDBG-R allocation, the City of Harrisburg acquired and is rehabilitating 4 vacant, abandoned, and blighted single-family housing units in targeted city neighborhoods. Rehabbed units will utilize ENERGY Star rated applicances, furnac
CDBG-R funds to be used for Public Facilities-Infrastructure Reconstruction: Curbs Sidewalk Streets
CDBG funds will provide financing for small businesses, infrastructure activites such as Crisp Ave Bridge, Mount Pleasant Center and paving and handicap curb cuts
Complete drainage restructuring in low income neighborhood. This will provide for better quality of living and increase property values in this area.  It will allow for better drainage in an adjoining commerical area.
To assist low-to-moderate income owner-occupied homeowners by helping to lower energy costs and providng energy efficient products where neede.
The proposed project is a public improvement project for the redevelopment of vacant land as a result of the 2003 tornadoes.  The project will prepare the site for future development of a mixed use development for commercial and housing.  The a
Administration - $11,946 Street Improvements - $33,000 Water/Sewer Improvements - $74,523
Morrell Blvd., 7th St., Decature St., W of N 6th St.
100 block through 600 block Morrell Blvd.
The CDBG-Recovery program invests in the rehabilitation of affordable housing and improves key public facilities, stabilizing communities and creating jobs in their communities.  The City of Dallas CDBG-Recovery program includes the following a
Public Improvements 03E, Monitoring Grant Compliance 21A, Community Courts 05, Public Services 05, 05M, Grant Administration and Oversight 21A, Indirect Cost 21B
Park Place Neighborhood - Reconstruction of streets, sidewalks, water and sewer lines.
2200 Blocks of Nix, Sam Houston, Reagan, Crosby, Nolan
2200 Block of  Ridgedale, Crockett, Bowie and Heartside
Originally funded seven construction projects; however, one project was cancelled.  This does not include CDBG-R administration.
The funding will be used to provide rehabilitation assistance for approximately eleven eligible low income families whose dilapidated homes are in need of repair.
CDBG-R funds were awarded for the construction of sidwalks and curb cuts in low income areas
CDBG-R Entitlement Funds.  The City of Fredericksburg, Virginia will use its CDBG-R funding to provide capital improvements at three sites.  One site is the Thurman Brisben Center, the local emergency homeless shelter.  The project will provide
South East Community Center/Renewal Community Infrastructure
USE CDBG-R FUNDS TO REHAB HOUSES IN COMBINATION WITH A NON-PROFIT* WEATHERIZATION PROGRAM TO BRING APPROXIMATELY 8-10 HOUSES TO LOCAL STANDARDS, ENHANCE ENERGY CONSERVATION, ASSIST THOSE MOST LIKELY IMPACTED BY THE RECESSION AND TO CREATE OR PR
CFDA COMMUNITY DEVELOPMENT BLOCK GRANT ENTITLEMENT/RECOVERY ACT FUNDED (CDBG-R)
Community Development Block Grant ARRA Entitlement Grants (CDBG-R - Recovery Act funded)
Kitsap Community Resources Weatherization and Minor Home Repair
Engineering and design service for Stormwater diversion project (mult-year).
Community development.  Street lights have been replace with LED lights to conserve energy and save money on energy costs.  A summer jobs program has been completed.  Family Services of Racine had an elevator installed in the entry way of their
CDBG-R activities include a wide variety of community development projects directed towards jobs training, education, handicap accessability, energy savings through streetlight retrofit.
The Recovery Act funding is intended to stimulate the economy through modernizing infrastructure and improving energy efficiency.
to replace fire suppression system in building E at LifeSteps Campus
LifeSteps Campus Fire Suppression System Replacement
The Community Development Block Grant (CDBG-R) program will enable the grantee to undertake elegible activities intended to create suitable living environments, provide decent affordable housing, and create economic opportunities, primarily for
Installation of solar hot water heating system
In complying with HUD's intended use of Recovery Act funds, it is proposed that Broward County will utilize $600,000 of its CDBG-R funds to address specific capital improvement and infrastructure projects in CDBG eligible low/moderate income ce
Single Family Residential Rehabilitation and Redevelopment Hard Costs, City of Dania Beach, City of Oakland Park, Town of Pembroke Park.
JAG funds will be used for law enforcement programs in the cities of Longview, Kelso & Woodland as well as Cowlitz County as part of a joint application.
The disparate jurisdictions of the Ponca City Police Department, Blackwell Police Department, and Kay County Sheriffs Office, all of Kay County, Oklahoma will use their Recovery Act JAG funds to support equipment and training enhancements. The
Ponca City Training Enhancement and Equipment Blackwell Police Department Equipment                Kay County Sheriff Equipment
2009 Recovery Act:  Law Enforcement Program Equipment  Through identified equipment purchases, the Prescott Police Department will enhance selected law enforcement programs to improve efficiency and service to the community.
2009 Recovery Act Law Enforcement Program Equipment
Funds for the expansion of the Lynnwood Police Department vehicle fleet (equipment) and expansion and enhancement of wireless access points.
This project is supported under FY09 Recovery Act(BJA-Byrne)Pub.L.No.111-5,42 USC 3750-3758.  The city of Grass Valley will use the Recovery Act Justice JAG funds to purchase one marked patrol vehicle for the Police Dept.  The acquisition of a
The City of Indianola and Sunflower County are disparate. The City of Indianola will purchase two vehicles.  Sunflower County will purchase one vehicle more suited for county rural roads.
Equipment is to be purchased for the Sheriff's Department as well as the City of De Queen Police Department
Fy2009 Recovery Act Justice Assistance Grant Program
The Vermilion Parish Sheriff's Office will use the Recovery Act JAG award to purchase a police interceptor for the Uniform Patrol Division to replace an existing patrol vehicle with higher mileage and multiple incidents of repair; acquire a mob
Vermilion Parish Sheriff's Office Technology Upgrade/Narcotics Enforcement
the disparate jurisdictions of City of Kenosha, Kenosha County and Village of Pleasant Prairie will use the grant funds to purchase and upgrade law enforcement equipment and technology.
The Brazoria County Sheriff's Department together with the cities of Angleton, Alvin, Pearland, Clute, Lake Jackson, and Freeport are purchasing law enforcement equipment enhancements.  The goal is to have better communication within each agenc
NORTHERN MAINE AND AROOSTOOK COUNTY LAW ENFORCEMENT EQUIPMENT UPDATE
LAW ENFORCEMENT COMMUNICATIONS AND EQUIPMENT UPGRADE
The Torrington Police Department will use its Fiscal Year 2009 Recovery Act JAG award to Purchase : (1) Mobile Radio with accessories (1) Portable Radio with accessories (2) Police Bikes with accessories (6) In car computers with accessories. A
Enhanced Law Enforcement Technological improvements for City of Muskogee Police Department and County of Muskogee Sheriff's Department to include but not limited to Vehicles, Vehicle Video Systems and Procurement of new patrol vehicles to repla
THIS PROGRAM IS GEARED TOWARDS UPDATING OUR OFFICERS EQUIPMENT FOR SAFETY AAND EFFICIENCY PURPOSES.
The disparate jurisdictions consisting of the City of Watertown and Jefferson County will use the ARRA funds to purchase equipment not funded and unable to be purchased otherwise.
Hiring of two new Communications Officers and Purchase of Equipment
Recovery Act Edward Byrne Memorial JAG Program
BJA FY09 Recovery Act Edward Byrne Memorial Justice Assistance Grant Program Local Solicitation.
FY 2009 Recovery Act JAG Program for Bristol County communities
The JAG will fund the continuation of the Kansas City Police Department Teleserve Unit. The Teleserve Unit takes police reports by which enables the Kansas City, Kansas, Police Department to operate more efficiently by allowing patrol officers
Equipment enhancement for the Lake Village Police Dept., Eudora Police Dept. & Chicot County Sheriff's Dept. with equipment enhancement such as new radars, digital cameras, handguns, etc.
Improvement of Public Safety and Prosecution through the use of technology
EL CENTRO FOR THE STUDY OF PRIMARY AND SECONDARY EDUCATION
El Centro for the Study of Primary and Secondary Education will develop Project Amigos, a community-based mentoring program developed in collaboration with San Manuel School District, Adelante Juntos Coalition, Sun Life Family Health Clinic, Sa
Adelante Juntos Coalition Project Amigos
BIG BROTHERS BIG SISTERS OF COLORADO, INC.
Local Youth Mentoring Initiative. The purpose of this project is to strengthen and expand Big Brothers Big Sisters of Colorado (BBBSC)'s one-to-one mentoring program for at-risk youth in Aurora, Colorado. To do this, BBBSC will partner with the
Big Brothers Big Sisters of Colorado's mentoring partnership to serve at-risk students in Aurora, Colorado
The Youth Opportunities Program (YOP), provides community-based mentoring for students at risk for dropping out of the Lawrence, Massachusetts schools.  The YOP program partners with the Lawrence Public Schools to identify students who have spe
South Bay Community Services (SBCS) provides comprehensive, neighborhood-based services for victims of domestic violence (DV) in close collaboration with local law enforcement agencies.  The Domestic Violence Resposne Team, which responds to ca
Resources and services for victims of domestic violence
Goodwill Industries International received a 24-month grant from the Office of Juvenile Justice and Delinquency Prevention to provide mentoring to youth, ages 12-17, who are at risk for juvenile delinquency.  The Goodwill GoodGuides Youth Mento
Goodwill GoodGuides Youth Mentoring Program
This Recovery Act Edward Byrne Memorial Competitive Grant Program supports the Santa Rosa Police Department with the preservation of eight police civilian personnel.
Preserving Santa Rosa Police Civilian Personnel
The Lowell Civilian Staff Hiring and Retention Initiative will enable the Lowell Police Department to retain and rehire civilian personnel, which will allow the LPD to maintain police presence on the streets of the city.
The Lowell Civilian Staff Hiring and Retention Initiative
WASHINGTON COUNTY YOUTH SERVICE BUREAU & BOYS & GIRLS CLUB
Residential Program for young men ages 18-22, just getting out of jail, that helps provide intensive case management, healthy lifestyle habits and life skills, structure and support while under DOC supervision.
Return House Transitional Living Reentry Program
BIG BROTHERS BIG SISTERS OF MEDDLE, TENNESSEE
OJJDP FY 09 Recovery Act Local Youth Mentoring Initiative
Big Brothers Big Sisters of Middle Tennessee Operation Mentor
The Charlotte-Mecklenburg Police Department (CMPD) was awarded $483,825 to fund its Neighborhood Crime Reduction program under Category IV: Hiring of Civilian Staff in Law Enforcement. The grant money will be used to fund four (4) crime analyst
Cass County Michigan Family Dependency Treatment Court
ALCOHOL & DRUG ADDICTION SERVICES, OHIO DEPARTMENT OF
Byrne Competitive Grants - provides funding for competitive, peer reviewed grants for units of state, local, and indian tribal governments, and to local, regional and national non-profit organizations to prevent crime, improve the administratio
BJA FY 09 Recovery Act Edward Byrne Memorial Competitive Grant Program: Supporting Problem Solving Courts
Enhancement of Therapeutic Services for survivors of sexual violence.
Enhancing Therapeutic Services for Survivors of Sexual Assault
This grant project is entitled the Prison Re-entry Initiative.  The project targets individuals who have a community based probation sentence in Maricopa County that follows a sentence of imprisonment with the Arizona Department of Corrections.
Maricopa County Recovery Act Prison Re-entry Initiative
Operation Home Defense will expand the City of Phoenix's capacity to address the alarming rise in border-related crimes. It incorporates a targeted joint law enforcement component utilizing the police department's expanded Home Invasion and Kid
The Amachi Mentoring Coalition Project is designed to prevent and reduce delinquent behavior and victimization and preserve and create jobs to serve youth and families most impacted by incarceration.
The purpose of this competitive grant is to help prevent and reduce violent crime in the Community by enforcing sex offender registration requirements and by educating the community on how to access sex offender registration resources.  Project
Multnomah County District Attorney?s Office Sex Offender Registration Detail (SORD)
Gender Specific Women's Case Management - Clark County District Court Corrections Women's Program. Purpose - Retention of a community-based probation supervision program that is a strategic, multi-dimensional, and research-based response to fem
Gender Specific Women's Case Management - Clark County District Court Corrections Women's Program
BYRNE COMPETITIVE: PROVIDE FOR FUNDING FOR NEIGHBORHOOD PROBATION AND PAROLE OFFICERS.
The National Criminal Justice Association (NCJA) is partnering with the Bureau of Justice Assistance (BJA) to work collaboratively with state administering agencies (SAAs) in developing statewide plans and using evidence-based practices and dat
Recovery Act Training and Technical Assistance Program
To implement an effective and sustainable investigative capability within the police department, to reduce drug related crime and to increase felony and drug related crime cases solve rastes.  An investigator was hired and will recive specializ
Ellington Drug and Crime Investigations Capability Implementation Program
Project Goals:  - Reduce the number of narcotics traffickers through the professional investigation, apprehension and conviction of criminals  - Enhance the drug detection canine program - Enhance DHE training to increase officer and community
BJA FY 09 Recovery Act Rural Law Enforcement Assistance:  Combating Rural Crime
Enhance Ohio AFIS to Include Palm Prints and Mug Shots:  The purpose of this project is to improve access to criminal justice data for law enforcement agencies located in rural Ohio counties. At the conclusion of the project, rural law enforcem
FY 2009 Recovery Act Rural Law Enforcement Assistance.   Combating Rural Crime.  Administered by BjA, helps rural states and rural areas prevent and combat crime, especially drug-related crimes, and provides for national support efforts includi
Nevada Law Enforcement Submissions to N-DEX
BJA FY 09 Recovery Act Rural Law Enforcement Assistance Combating Rural Crime - For retention of two Shelton Police Department commissioned officers in order to continue crime prevention activities within the City and surrounding areas.
The city of Fortuna will use its award to support the Fortuna Police Department (FPD), which is a small department of 15 sworn personnel serving a rural community. Crimes have increased steadily over recent years, and staffing shortage affects
Fortuna Police Department Investigations Unit Project
BJA FY 2009 Recovery Act Assistance to Rural Law       Enforcement to Combat Crime and Drugs: Enhancing Rural Corrections,       Detention & Jail Operations.  The goals are to increase manpower over the long term to limit liability and saftey i
Multi-County regional Records Management System - Bates County, Dade County, Vernon County, and St. Clair Coounty, MO
The project objective for this program will be first and foremost to maintain the department's force size, which will enable the Police Department to more adequately fulfill the traditional police duties. The sworn officers that will be funded
West Frankfort City Anti Drug and Crime Initiative
Restoring Proactive Drug Enforcement in Arenac County
FY09Recovery  Act rural Law Enforcement Assistance; Combating Rural Crime
The Idaho State Police (ISP) will expand its criminal information-sharing capabilities. ISP hosts the Idaho Criminal Intelligence Center (IC)2, a  federal, state, and local criminal information-sharing facility. (IC)2 is implementing a pioneer
Assistance to Rural Law Enforcement to Combat Crime and Drugs
JUDICIARY COURTS OF THE STATE OF LOUISIANA
Hiring community member as entry-level Probation Officer. Each will undergo a basic level of training conducted by experienced staff.  Each will perform basic probation duties to enhance the Tribal Court and gain work experience.
The award will allow Laurens County Sheriff's Office to fill five positions frozen by the Laurens County Commission. It will also assure the retaining of three other positions that were being considered for layoffs. The five frozen positions co
Tri-County Community Corrections will utilize the award to achieve its fundamental goal of reducing offender recidivism by establishing three specific project goals.  These project goals are expanding options for managing inmate behavior; enhan
Tri-County Community Corrections Rural Detention/Jail Operations Project is a three rural northwestern Minnesota counties project for improvement of jail classifications, jail programming and staff training.
Combating Rural Crime Through Saturation and Reduction of Crime
The Navajo Nation Nabinahaazlaago Initiative will ensure assessments, services, and treatment are provided for juveniles in detention, and ensure data collection and reporting on recidivism; and in doing so create 11 new jobs.
Vermont's Rural Law Enforcement to Combat Crime and Drugs Grant
Category IV: Facilitating Rural Justice Information Sharing  Funding this application will provide the resources to complete the final link allowing law enforcement officers in Grant County WA to access local, state and federal data bases and i
CRIME CONTROL AND PUBLIC SAFETY, NORTH CAROLINA DEPARTMENT OF
The North Carolina Victim Compensation program pays expenses and losses to or on behalf of individual victims of violent crime.  These expenses and losses include medical, counseling, funeral bills and wage losses.  These payments contribute to
North Carolina Victim Compensation Commission
The purpose of this project is to support the provision of crucial financial assistance to victims throughout Idaho. Through VOCA Recovery Act funding, Idaho will provide compensation to victims and survivors for the following four categories o
The Crime Victims' Compensation Program will provide benefits to victims of violent crime in Texas who meet eligibility requirements according to Texas Code of Criminal Procedure, Chapter 56, Subchapter B.
The MT Crime Victim Compensation Program provides payment of medical expenses to or on behalf of victims injured in a personal injury crime.
VICTIM COMPENSATION AND GOVERNMENT CLAIMS BOARD
Grant - The funds will be used to compensate victims and survivors of crime for the following expenses: medical expenses, mental health counseling and care, loss of wages, and funeral expenses.  Other expenses may be authorized by a state statu
VCGCB 400 R Street, Ste 500, Sacto., CA 95811-0000
Provided additional compensation assistance to victims of crime for loss of earnings, burial, medical bills, counseling, loss of support.
Recovery Act - OVC FY 09 VOCA Victim Compensation Formula Grant Program.
OVC FY 09 VOCA Victim Compensation Formula Grant.  The State Crime Victim Compensation Program supplements states’ and territories’ efforts to compensate crime victims. States and territories use these funds to reimburse victims for crime-r
Recovery Act-OVC FY 09 VOCA Victim Compensation Formula Grant Program
I-4/SELMON EXPRESSWY FROM S OF SELMON EXPRSSWY TO I-4
SR 260 Porter Mountain Rd - Woodland Rd - Pinetop
The Minnesota Chippewa Tribe is operating a business development center to service Native Americans residing in the rural counties of St. Louis, Koochiching, Mahnomen, Becker, Clearwater, Cook, Beltrami, Cass, Hubbard, Carlton, Itasca, and Mill
Minnesota Chippewa Tribe Business Development Center
The purchase of two Police vehicles will save the City on repair and fuel costs.
I-287 Vicinity of Stelton Road to Vicinity of Main St, Resurfacing, construction
Bridge Deck Replacement Program I-287 NB over Rt 46, Construction
Highway Infrastructure Investment Grant: Areas with Population equal to or less than 200K, Urbanized Areas over 200K Population
50 S American Fork 700 East to 1100 East
The New York State Department of Transportation was awarded a National Clean Diesel Funding Assistance Program Grant to fund a repower project targeting one railroad switch locomotive in Albany County, New York. The general purpose of the grant
CSX Genset Technology Switch Locomotive Engine Repower
MID-ATLANTIC REGIONAL AIR MANAGEMENT ASSOCIATION INC
MARAMA was awarded a National Clean Diesel Funding Assistance Program Grant to fund vehicle replacement, repower and retrofit projects targeting transit buses, non-road vehicles, boats, dump trucks, a locomotive, and diesel-powered materials ha
2009 Mid-Atlantic Diesel Emission Reduction Campaign
SOUTH COAST AIR QUALITY MANAGEMENT DISTRICT
South Coast AQMD was awarded a Clean Diesel Emerging Technology Program Grant to fund a retrofit project targeting Class 8B heavy-duty, on-highway, diesel trucks in California's South Coast Air Basin.  The general purpose of the grant is to red
Georgia Department of Natural Resources (DNR) was awarded a National Clean Diesel Funding Assistance Program Grant to fund a truck stop electrification project targeting truck stop parking spaces in Georgia.  The general purpose of the grant is
National Clean Diesel Funding Assistance Program - Georgia Truck Stop Electrification (TSE) and Green Corridors
ETCFC was awarded a National Clean Diesel Funding Assistance Program grant, to fund the installation of 50 truck electrified spaces at the Plateau Travel Plaza in Crossville, TN in order to reduce diesel emissions like nitrogen oxides and fine
Puget Sound Clean Air Agency was awarded a National Clean Diesel Funding Assistance Program Grant to fund a repower project or program targeting private locomotive switcher engines operating in the Puget Sound region.  The general purpose of th
Locomotive Repower Project for Puget Sound
Cascade Sierra Solutions was awarded a National Clean Diesel Funding Assistance Program Grant to fund a retrofit program targeting fleets and single trucks in Connecticut, Maine, Massachusetts, New Hampshire, Rhode Island and Vermont. The gener
NORTH CENTRAL TEXAS COUNCIL OF GOVERNMENTS
North Central Texas Council of Governments (NCTCOG) was awarded a National Clean Diesel Funding Assistance Program Grant to fund a replacement and repower program targeting on-road heavy-duty diesel vehicles traveling in or through the Dallas-F
The State of Wyoming was awarded a National Clean Diesel Funding Assistance Program Grant to fund a retrofit (EUGs) and repower project targeting non-road equipment in Sublette County. The general purpose of the grant is to reduce diesel emissi
ARRA National Clean Diesel Program - WY DEQ
Cascade Sierra Solutions was awarded a National Clean Diesel Funding Assistance Program Grant to fund a retrofit program targeting fleets and single trucks in Colorado, Montana, North Dakota, South Dakota, Utah, Wyoming. The general purpose of
ARRA National Clean Diesel Program - CSS
Revolving Loan Fund Program to support the cleanup of brownfields properties located in the City of City of Saint Paul, with special emphasis on the Phalen Corridor, the Great Northern Corridor and the University-Midway Corridor.
Revolving Loan Fund Program (Hazardous Substances) for the City of Saint Paul with special emphasis on three Corridor Project Areas.
EPA funding for Revolving loan funds to remove hazardous substances and petroleum hazards through awards for cleanup activity  to eligible entities.
BROWNFIELD REDEVELOPMENT AUTHORITY OF JACKSON COUNTY, THE
ARRA-Jackson County Brownfield Redevelopment Authority Revolving Loan Fund.
This agreement provides ARRA funds as an additional financial assistance source for the recipient's efforts to cleanup hazardous substance and petroleum-contaminated Brownfield sites in Indiana.
Revolving Loan Fund for Hazardous Substances and Petroleum; provides supplemental funding to Indiana's RLF Program for cleanup loans and sub-grants to eligible entities.
American Recovery and Reinvestment Act funds will be used by Land of SKy Regional Council to provide loans and subgrants to eligible entities for cleanup planning and remediation of hazardous and/or substances and petroleum contaminants at Brow
Combined Haz Substances & petroleum revolving loan fund.
Stimulus regional hazardous substances assessment grant.
Cleanup of hazardous substance contaminants at the H.J. Mills Property Lot 49-50 site along with community involvement activities to encourage redevelopment of the site such that the future reuse of property will create/retain jobs and does not
Hazardous Substances Cleanup at H.J. Mills Property Lot 49-50, Bristol, CT - Cooperative Agreement
GPCOG Brownfields Assessment program for petroleum sites.
New Bedford Brownfields Assessment Program
Community Wide Environmental Assessment  Cooperative Agreement
This award provides stimulus funding to the City of Worcester, MA for a Revolving Loan Fund to assist with  cleanup planning and remediation activities. The purpose of these activities is to promote the redevelopment and future reuse of sites i
Worcester Supplemental Revolving Loan Fund
City of Camden Redevelopment Agency 2009 U.S. EPA Brownfields Hazardous Substances Assessment Grant
Performing environmental assessment activities at eligible brownfields properties contaminated with hazardous substances located in Camden.
Jersey City Redevelopment Agency U.S. EPA Brownfields Cleanup Grant: JR Transportation Site
Conducting a hazardous substances cleanup at the JR Transportation site.
US EPA Petroleum Grant for Phase I and II Environmental Assessment
Immediate Office of the Administrator of EPA
This award provides American Recovery and Reinvestment Act funds to the St. Louis Development Corporation (SLDC) to provide a Brownfields Revolving Loan Fund (RLF) for the community to assist funding cleanup planning and remediation activities.
ARRA St. Louis Development Corporation Brownfields Supplemental RLF
Grant to fund Revolving Loan Fund program for the City of Missoula to facilitate hazardous substances cleanup loans and grants to eligible entities.
City of Missoula Brownfields Revolving Loan Fund
Hazardous Substances Site Specific Cleanup
Asbestos Abatement at Paxson Building Site
ENVIRONMENTAL PROTECTION, NEVADA DIVISION OF
This federal grant provides funding to the State of Nevada to support the School Bus replacement program. The project has two goals: 1) to reduce the exposure of school-age children to particulate matter and other harmful components of diesel e
Vermont Department of Environmental Conservation was awarded a State Clean Diesel Program Grant to fund a replacement program targeting school buses in Vermont. The general purpose of the grant is to reduce diesel emissions and improve air qual
STIMULUS Vermont State Clean Diesel Grant Program
NMED WAS AWARDED A STATE CLEAN DIESEL PROGRAM GRANT TO FUND A RETROFIT TECHNOLOGY PROGRAM FOR FLEET IN NEW MEXICO. GENERAL PURPOSE OF THE GRANT IS TO REDUCE DIESEL EMISSIONS AND IMPROVE AIR QUALITY.
Wilmington, Greenwood, Smyrna, Millsboro, Seaford, and Bridgeville will receive funding for drinking water infrastrucutre improvements.  The grant will also fund associated administrative FTEs through the 4% set-aside.
Funding under ARRA 2009 to capitalize revolving loan fund for financing construction of drinking water facilities, green infrastructure, program admin and drinking water related activities.  Will preserve and create jobs & promote economic reco
These funds will be utilized by the State of Tennessee to capitalize its revolving loan fund for the financing for the construction of drinking water facilities, green infrastructure, program administration and drinking water related activities
Drinking Water State Revolving Fund (SRF) American Recovery and Reinvestment Act of 2009 (ARRA) capitalization grant for the State of Florida to fund Public Water System treatment, storage and distribution systems.
The Safe Drinking Water State Revolving Funds are awarded under the American Recovery and Reinvestment Act of 2009 to the State of Mississippi to capitalize our revolving loan fund for the financing for the construction of drinking water facili
Mississippi Drinking Water State Revolving Loan Fund
The award will be used to fund infrastructure improvements to the State’s public drinking water systems.  The outcomes will be operational and maintenance improvements of public health protection and drinking water quality for water system us
ENVIRONMENT AND NATURAL RESOURCES, SOUTH DAKOTA DEPARTMENT OF
This is the Federal Fiscal Year 2009 Drinking Water State Revolving Fund (DWSRF) stimulus grant provided by the American Recovery and Reinvestment Act of 2009.  It will provide a source of financing for the construction of water treatment facil
FY 09 Stimulus Grant for Large Valve Replacement Contract 8
This award provides stimulus funding for training local residents in the skills necessary to gain employment with companies that assess and remediate brownfield properties in the City of Richmond.
Richmond Brownfields Job Training Cooperative Agreement
ARRA funding to train City residents in skills necessary to gain employment with firms, and contractors that are directly involved in Brownfield Cleanup and Redevelopment, and all related green industry positions in the City of Miami Florida.
American Recovery and Reinvestment Act, Brownfield Job Training Grants
Citizens impacted by Brownfields receive Environmental job training in projects that will facilitate the creation of jobs dealing with assessment, remediation or preparation of Brownfields sites.
Brownfield Job Training Cooperative Agreements
This agreement provides ARRA funds as an additional financial assistance source for the recipient's efforts to assess and cleanup petroleum releases from leaking underground storage tank (LUST) sites in Mississippi. The agreement will fund seve
Formula Grant to State Agency for cleaning up releases from petroleum underground storage tanks.
This agreement provides American Recovery and Reinvestment Act funds as an additional assistance source for the recipient's efforts to assess and cleanup petroleum releases from leaking underground storage tanks (LUST) sites in South Dakota.  T
ENVIRONMENTAL QUALITY, MICHIGAN DEPARTMENT OF
The Michigan Department of Environmental Quality (MDEQ) received $1,702,100 from the U.S. Environmental Protection Agency under the 205(j) Water Quality Management Planning Program, funded from the 1% reserve from the Clean Water State Revolvin
FY 2009 American Recovery and Reinvestment Act Water Quality Management Program
The Biodemographic Determinants of Life Span-a collaborative effort between demographers/ biologists to bear on questions that are at the interzone between the biology of aging/formal demography, particularly  questions concerned with the evolu
The Biodemographic Determinants of Life Span
Program Director/Principal Investigator (Last, First, Middle): Kuhn, Richard J. 2 P01 AI055672-06A1 ABSTRACT The current understanding of alphavirus and flavivirus life cycles at the molecular level is incomplete because we lack a structural fo
Structure-function Studies of Alpha- and Flaviviruses
Overall Project : Francisella tularensis is considered to be a Category A agent by the NIAID because of its extreme infectivity, ease of dissemination, and substantial capacity to cause illness and death. This Program Project brings together a
Mucosal Immunopathogenesis of Francisella tularensis
Project 1 aims to identify the brain networks influenced by acupuncture and to explore the interactions among those brain regions in both healthy subjects and in patients with major depressive disorder (MDD). We hypothesize that the limbic syst
Neuroimaging Acupuncture Effects on Human Brain Activity
The overall purpose of this award was to fund the conduct of an in-progress research study.  The purpose of the research study is to find out if melanoma can be treated by removing only a few lymph nodes (called ?sentinel nodes?) from a lymph b
Funds will support efforts to promote long term economic benefits for the state by planning for the provision of water resources. The State of Georgia will complete analytical modeling tools and generate data on assimilative capacity for select
This project supports water quality management planning activities that are authorized under the Clean Water Act and the American Recovery and Reinvestment Act of 2009.  This project will fund two objectives: 1) to assess green infrastructure a
Water Quality Management Planning - American Recovery and Reinvestment Act
This project supports water quality management planning activities authorized under the Clean Water Act and the American Recovery and Reinvestment Act of 2009. This project will develop limits for the loading of pollutancts into the Green Cay-T
2009 Maryland Department of the Environment ARRA WQMP Grant.  This project supports water quality management planning (WQMP) activities that are authorized under the Clean Water Act and the American Recovery and Reinvestment Act of 2009 (ARRA).
FY 2009 Maryland Department of the Environment ARRA WQMP Grant
Pneumonic plague is highly lethal in humans, and the agent of this disease, Y. pestis, is considered a major threat as a biological weapon. Current strategies to prevent pneumonic plague, such as the use of vaccines or antibiotics, are non-effe
ARRA:  Agents of Bioterrorism:  Pathogenesis and Host Defense
NATIONAL OLDER WORKER CAREER CENTER, INC.
This Cooperative Agreement will provide support for Senior Environmental (SEE) Program enrollees to work in the various offices in EPA's Region VII Operations and to support EPA stimulus activities in accordance with the American Recovery and R
SEE Program for Region 7 Operations Stimulus Activities
Study of Osteoporotic Fractures Renewal. Data analysis and manuscript preparation.
Leishmaniasis is a major health problem in humans and is caused by the protozoan parasite Leishmania. Depending on the species, Leishmania-induced pathology ranges from self-healing, cutaneous lesions to fatal, visceral diseases. Our laboratory
DRUG RESISTANCE AND PTERIDINE METABOLISM IN LEISHMANIA
The murine antibody repertoire experiences a series of expansions and contractions that coincide with specific stages of B-cell development and differentiation. The initial repertoire of antibody specificities generated by V(D)J recombination i
Analysis of the Murine Antibody Repertoire
Amalgamating the tools and techniques of molecular biology, genetics, biochemistry, and pharmacology, this competing renewal application offers an experimental paradigm to validate key components of the polyamine pathway of Leishmania and to im
Comstock, Laurie E. A10441 93-A2 The Bacteroides are one of the numerically dominant genera of bacteria of the human intestinal microbiota where they are mutualistic symbionts providing beneficial properties to the mammalian host. If Bacteroide
Regulation of the Multiple Polysaccharides of Bacteroides Fragilis
Klebsiella pneumoniae is an opportunistic pathogen frequently implicated in respiratory and urinary tract infections of hospitalized patients. In addition, it is a leading cause of pneumonia in chronic alcoholics and has also been associated wi
Molecular Pathogenesis of Klebsiella Pneumonia
The proposed studies will not only help elucidate the pathogenic mechanisms of autoimmune encephalomyelitis but also aid in developing specific strategies targeting c Rel for the treatment of multiple sclerosis.
that spans both the inner and out membranes of the bacterium, projecting a filamentous needle-like protein into the extra-cellular space. The virulence factor substrates of T3SS are biochemically diverse, manipulating host cell biological syst
Structural studies of bacterial virulence factors
Cryptosporidium parvum and C. homonis are opportunistic protozoan parasites frequently infecting AIDS patients and other immune-compromised individuals. The long-tem objective of this research is to use genetic methods to identify genes control
This NIH NIAID RO1 competing continuation grant received ARRA support for years 6 and 7 to investigate how West Nile virus [WNV] persists and amplifies within the varied biomes of California.  The project start date was 1 Jun 09.  Funding trans
Persistence of West Nile virus in California
This grant award provides funds from the American Recovery and Reinvestment Act of 2009 (the 'Recovery Act') to enhance crime victim services in the state. The Recovery Act - OVC FY 09 Victims of Crime Act (VOCA) Victim Assistance Formula Grant
This grant award provides funds from the American Recovery and Reinvestment Act of 2009 to enhance crime victim services in the state.  The Recovery Act Victims of Crime Act (VOCA) Victim Assistance Formula Grant Program funds are competitively
Victims of Crime Assistance Program - ARRA
Recovery Act - Office for Victims of Crime, Victim Assistance FY09 VOCA Victim Assistance Formula Grant Program
Title of Project: Traffic Safety and Speed Reduction Project  Traffic safety poses an increasing challenge for the Breckenridge Police Department.  The Police Department is seeking new methods for educating citizens and visitors, reducing vehic
Traffic Safety and Speed Reduction Project
This study is designed to help law enforcement combat technology-facilitated child exploitation crimes. It will gather detailed national data on a number of policy and practice relevant topics including: 1) new developments and numerical trends
Study of Scope, Investigation, and Prosecution of Technology-Facilitated Child Exploitation Crimes: The 3rd National Juvenile Online Victimization Study
The proposed research project is a content and process evaluation of internet safety education materials currently utilized by the Internet Crimes against Children (ICAC) Task Forces in school and community settings across the country. Despite
Process Evaluation of Current Internet Child Safety Activities by ICAC Task Forces
FY 09 Recovery Act Internet Crimes Against Children Task Force Program Grants Program - The Delaware Department of Justice (DOJ) requests OJJDP Recovery Act ICAC funding to enhance the Delaware Internet Crimes Against Children Task Force’s ab
Delaware Child Predator Task Force - Enhancing the task force's ability to arrest and prosecute online child exploitation offenders.
The North Florida ICAC Task Force will utilize the grant to maintain and expand state and regional ICAC task forces to address technology-facilitated child exploitation to prevent, interdict, investigate, and prosecute Internet crimes against c
OJJDP FY 09 Recovery Act Internet Crimes Against Children Task Force Program Grants Program
Reduce the number of backogged child sexual exploitation investigations pending forensic examination of seized computers.  A forensic examiner will be hired with grant funds to conduct backogged forensic examinations.
Recovery Act Internet Crimes Against Children Task Force Program grants seek to maintain and expand state and regional ICAC Task Forces to address technology-facilitated child exploitation.
The Arkansas State Police Internet Crimes Against Children Task Force ($580,983.00) will use ARRA grant funds to support 3 positions:  a Forensic Specialist, an Intelligence Analyst, and an Administrative Specialist for 48 months each.  The ICA
The Recovery Act grant monies will address personnel needs, technology, and training that supports protection of children from exploitation via technology. This focus will be directed at the addition of dedicated personnel to support the effor
PURPOSE:  To employ an organizational strategy to build new partnerships with entities and institutions that can provide further technological assistance through current federal funding.   POPULATION TO BE SERVED:  To provide funding for staffi
Grant No. 2004-IJ-CX-K035 required the fabrication/demonstration of a high power solid state (SS) radio frequency (RF) directed energy (DE) weapon brassboard. This was essentially a lab demonstration model and does not resemble the envisioned h
Continuation of Award No. 2004-IJ-CX-K035, Less-Lethal Technologies-Area Denial of Personnel; Solid State Active Denial System Demonstration Program
Military Armored Vehicle, Tank, and Tank Component Manufacturing
The objective of Phase II of this program is the fielding of a universal cutting tool that will interface with any of the existing common EOD robots such as the Andros series, Talon, Pacbot and Vanguard.  The system will be designed to fit with
Double Dervish: EOD Universal Cutting Tool
Program Abstracts:  The U.S. Department of Justice Office of Justice Programs has approved TDCJs application for funding under the FY09 Recovery Act Combating Criminal Narcotics Activity Stemming from the Southern Border of the United States: C
The grant funds a two-year project through which The Pima County Attorney's Office will: organize and work in tandem with law enforcement to collect, analyze and share information about drug-related crime trends stemming from the County's  shar
The Enhanced Prosecution of Drug and Border Related Crimes
FY 09 Recovery Act (BJA -Tribal Lands Correctional Facilities Construction/Renovation. Renovation of Correctional Facilities on Tribal Lands Discretionary Grant Program assists tribes in developing strategies to cost effectively construct or re
The Edward Byrne Memorial Justice Assistance Grant (JAG)Program is the primary provider of federal criminal justice funding to state and local jurisdictions.  JAG funds support all components of the criminal justice system, from multi-jurisdict
State of Colorado 2009 Edward Byrne Memorial Justice Assistance Grant Recovery Act Program
The Arizona Criminal Justice Commission (ACJC) is a statutorily authorized entity mandated to carry out various coordinating, monitoring, and reporting functions relating to the administration and management of criminal justice programs in Ariz
The 2009 ARRA JAG program initially  focused on priortizing funding to multi-jurisdictional task forces at the state and local level, information technology projects primarily through the Nebraska Criminal Justice Information System (NCJIS) and
The Office of the Governor - Criminal Justice Division (CJD) will utilize its Fiscal Year 2009 Recovery State allocation to fund programs under the following purpose areas:  law enforcement, drug treatment and enforcement, prosecution and court
The purpose of the Recovery Act-Tribal Crime Data Collection, Analysis and Estimation program is to improve the utility of tribal crime and justice data for use in the Edward Byrne Memorial Justice Assistance Grant Program formula grant calcula
BJS FY09 Recovery Act - Tribal Crime Data Collection, Analysis and Estimation Project.
The rapid technological and procedural developments surrounding the use of forensic DNA make this science one of the most exciting and effective tools in criminal justice today. For crime victims, more widespread collection and use of DNA evide
Training and Technical Assistance on the Impact of Forensic DNA on Victims for Victim Service Providers and Allied Professionals
Ex-Offender Community Service/Employment Initiative in a Weed and Seed District
Community Service Employment Initiative in a Weed and Seed District
WEST HOUSTON ADVANCED TRAFFIC MANAGEMENT SYSTEM
This ARRA project is being implemented in order for the FWS and TNC to work together for the purpose of implementing prescribed burns on private lands targeting HUC units associated with the black bear recovery efforts in East Texas.  With the
This ARRA project is being implemented in order for the FWS and Mallet Ranch to work together to restore habitat (approximately 1,737 acres) for the candidate lesser prairie-chicken and other grassland dependend species.
Highway Infrastructure Investment Grant:  Available for Use in Any Area (Flexible) and Rural Areas with Population under 5K
Safety and Resurfacing Chestnut Grove Road to Lee Road
SR 23 (BFCR) OVERPASS @ PLANTATION OAK BLVD.
The City of Noblesville is using its Fiscal Year 2009 Recovery Act JAG award to purchase e-citation printers for patrol cars, moving radar equipment, and F/X conversion kits for firing range training.
Equipment for Noblesville Police Department
CMC 2215 - From 5 Miles South of ND 36, N
TCAP funds to rehabilitate multi-family housing
Highway Infrastructure Investment Grant:  Avaiable for Use in Any Area
Safety and Resurfacing Improvements Milestone Drive to Venice Drive
SYLVAN BEACH PEDESTRIAN CONNECTION PROJECT, V/ SYLVAN BEACH
MOHAWK ST BEAUTIFICATION ENHANCEMENT PROJECT, V/ HERKIMER
SR32 REPLACE 4 BR BETW YALO C/L & SR 330 & SR32 REPLACE 5 BR BETW OLD SR 7 & CALHOUN C/L Bridge
Wisconsin Department of Commerce was awarded a National Clean Diesel Funding Assistance Program Grant to fund a retrofit project targeting Wisconsin motor carriers statewide.  The general purpose of the grant is to reduce diesel emissions and i
Wisconsin Diesel Truck Idling Reduction Grant Program
The city of Phoenix was awarded a National Clean Diesel Funding Assistance Program Grant to fund a retrofit and replacement project targeting heavy duty diesel on road vehicles in the Phoenix metropolitian area. The general purpose of the grant
Southern Research Institute was awarded a Clean Diesel Emerging Technology Program Grant to fund a retrofit project or program targeting on-highway and nonroad diesel vehicles in Durham, NC. The general purpose of the grant is to reduce diesel
Emerging Technologies Southern Research Institute
The South Carolina Department of Education was awarded a State Clean Diesel Program Grant to fund a retrofit/replacement project targeting the school bus fleet in South Carolina.  The general purpose of the grant is to reduce diesel emissions a
National Clean Diesel Assistance Program
Miami-Dade County was awarded a National Clean Diesel Funding Assistance Program Grant to fund a project or program targeting agricultural irrigation sets in Miami-Dade County.  The general purpose of the grant is to reduce diesel emissions and
National Clean Diesel Funding Assistance Program Miami-Dade Clean Diesel Repower Subgrant/Rebate Program for Local Farmers
The Oklahoma Department of Environmental Quality was awarded a National Clean Diesel Funding Assistance Program Grant to fund a retrofit/replacement project or program targeting School Busses the potential non-attainment areas of the Oklahoma a
Oklahoma Clean Diesel School bus Program for Large Schools in Potential Non-Attainment
Cascade Sierra Solutions was awarded a National Clean Diesel Funding Assistance Program Grant to fund a retrofit program targeting fleets  in New Jersey and New York. The general purpose of the grant is to reduce diesel emissions and improve ai
Grace Hill Settlement House was a awarded a National Clean Diesel Grants Funding Assistance Program Grant to fund a retrofit/replacement/repower in St. Louis, Missouri.  The general purpose of the grant is to reduce diesel emissions and improve
American Revocery and Reinvestment Funds to Grace Hill - Naltional Clean Diesel Grant Program
Colorado Department of Public Health and Environment was awarded a National Clean Diesel Funding Assistance Program Grant to fund a retrofit project targeting over-the-road trucks in the Denver Metropolitan Area. The general purpose of the gran
ARRA National Clean Diesel Funding Assistance Program
The Regional Air Quality Council was awarded a National Clean Diesel Funding Assistance Program Grant to fund a retrofit and engine repower program targeting over-the-road trucking fleets, oil and gas fleets and school districts.  The general p
Stimulus funding to be used to conduct community-wide assesments at brownfield sites potentially contaminated with hazardous substances
Stimulus Brownfields Hazardous Substance Assessment
The Idaho Department of Environmental Quality (IDEQ), the State of Idaho?s environmental authority, was recently selected to receive a $650,000 award for an Environmental Protection Agency (EPA) Coalition Assessment Community Wide Hazardous Sub
Pend Oreille Bay Trail Brownfields Assessment Coalition Grant
This is an American Recovery and Reinvestment Act funded site assessment in the City of Merced, California. A site specific assessment will be performed on a parcel with gasoline impacts to groundwater.  The Redevelopment Agency of the City of
EPA community-wide assessment grants (petroleum & hazardous substances) for the West Oakland area of the City of Oakland, CA
ARRA Brownfields Assessment Cooperative Agreement.  This award provides stimulus funding to be used to conduct Community-Wide assessments at potential Brownfields sites contaminated with petroleum products and/or hazardous substances.  South Tu
Brownfields Community-Wide Assessment for Hazardous Substances and Petroleum Products within the City of South Tucson, Arizona
American Recovery and Reinvestment Act funds will be used by the Housing Authority of the City of Aiken to conduct community-wide environmental assessments at brownfield sites which are potentially contaminated with petroleum and/or hazardous s
Performing environmental assessment activities at eligible brownfields properties contaminated with hazardous substances and petroleum located in targeted community.
City of Tampa, Florida $400.000 Community-Wide Brownfields Assessment Grant for Hazardous Substances and Petroleum Products Project
The vitamin D receptor (VDR) is a transcription factor that mediates the actions of 1,25-dihydroxyvitamin D3 (1,25(OH)2D3) in the nucleus of target cells. The receptor binds in a cell-specific manner to target genes and regulates their transcri
ARRA BONE CELL REGULATION OF THE VITAMIN D RECEPTOR GENE
Angiogenesis, the growth of new blood vessels, promotes tumor growth and metastasis. During the previous grant cycle, we found that the fibronectin receptor integrin a4_1 promotes tumor angiogenesis by distinct endothelial cell- and myeloid cel
The proposed research is designed to develop a novel way to engage killer T cells and helper T cells (two important players in the immune system) to work in a collaborative and synergistic manner so as to orchestrate a robust and long-lived cel
TCR ENGINEERED CD4 CELLS AS HELPERS IN TUMOR IMMUNITY
Cancer is caused by the activation of oncogenes and the inactivation of tumor suppressor genes. The targeted inactivation and repair of these gene products may be a specific and effective therapy for cancer. Previously, we have shown that the i
Molecular and Cellular Basis of oncogene Addiction
Environmental and endogenous exposure to chemicals that produce DNA-protein and DNA-peptide crosslinks are correlated with an increased risk of several cancers, asthma, and other diseases. Currently many thousands of individuals in the US popul
Cellular Responses to DNA-Protein Crosslinks
The psychoactive component of marijuana, ??9-tetrahydrocannabinol, binds to and activates cell surface receptors called cannabinoid receptors. Activation of these receptors produces intense responses in humans, which suggest that endogenous can
Characterization of a Novel Brain Cannabinoid Ligand
DESCRIPTION (provided by applicant): The dopamine transporter (DAT) is the primary mechanism by which extracellular dopamine (DA) is cleared from the synaptic space. As such it performs a key role in terminating dopaminergic neurotransmission
PHOSPHORYLATION AND REGULATION OF DOPAMINE TRANSPORTERS
The relevance of this research is for providing guiding information and principles concerning the understanding of both the normal processes and the drug-induced changes involved in the long-term consequences of drug exposure in the neural circ
Cocaine-Induced Metaplasticity in the Hippocampus
The long-term objective of this project is to identify new, more effective, and less toxic therapies for Head and Neck Squamous Cell Carcinoma (HNSCC) and related cancers, by understanding the function and regulation of the p53 family members p
P63 Mediators as Therapeutic Targets in HNSCC
Illuminating the arc of molecular events from chronic hepatic injury and fibrosis through hepatocellular carcinoma (HCC) remains the most fundamental challenge in investigative hepatology The overall goal of this application is to elucidate th
THE ROLE OF KLF6 TUMOR SUPPRESSOR IN HEPATOCELLULAR CANCER
During aging, an increasing proportion of total lens proteins becomes water insoluble (WI) either due to aggregation and/or cross-linking. The increased sizes of cross-linked multimers of crystallins become so large that they finally become wat
PROTEINASE INHIBITORS & CRYSTALLIN FRAGMENTS IN CATARACT
The goal of this grant proposal is to use newly developed transgenic mouse models to 1) elucidate the role of keratocan-expressing cell lineage in corneal morphogenesis during development and in the maintenance of corneal stromal homeostasis in
This is an ARRA award to support the research of R01 EY013135 entitled, 'Spatiotemporal Maps & Interactions in V1 & V2 Neurons.' The proposed experiments will use physiology to measure single-neuron responses to classical visual illusions, whic
Spatiotemporal Maps and Interactions in V1 and V2 Neurons
Abstract: DESCRIPTION (provided by applicant): Hypoxia is a natural state in the lens. In order to prevent hypoxia-driven apoptosis the lens has two stress switch protein kinase C (PKC) isoforms, PKC3 and PKC5. Both of these PKC isoforms have C
Our long term objectives are to understand the biochemical mechanisms that cause the feedback inhibition of hormonal or drug stimulation of the 22-adrenergic receptor (22AR) that mediates several important components of the 'fight-or-flight' re
BETA ANDRENERGIC RECEPTOR STRUCTURE AND DESENSITIZATION
Epigenetic modifications modulate gene expression in normal development and in diseases, such as cancer. X chromosome regulation is an example of coordinate epigenetic regulation of gene expression at the level of an entire chromosome. Our goal
Carbohydrates can be used as vaccines if they are covalently conjugated to a carrier protein. However, some carbohydrate antigens remain poor immunogens even when coupled to a protein. To overcome this weakness, chemical alteration of the nativ
Computational Analysis of Carbohydrate Antigenicity
Abstract: The objective of this proposal is to understand the mechanism for the 5’ strand-specific end processing of DNA double-strand breaks (DSBs) in eukaryotes. DSBs are among the most deleterious types of DNA damages. If not properly repa
Werner Syndrome Protein, DNA End Processing, and Double-Strand Break Repair
The long-range goals of this project are to use polypyrrolebased anion receptors to understand the fundamental factors that regulate anion recognition and transport processes in biology and to develop synthetic systems that are useful in the di
Dicer is a nuclease involved in processing double-stranded RNA (dsRNA) into small RNAs called siRNA and miRNA. These small RNAs are involved in regulating the expression of numerous genes, in diverse organisms, including humans. The proposal wi
THE RIBONUCLEASES INVOLVED IN RNA INTERFERENCE
DExD/H-box proteins are required for virtually every process carried out by structured RNAs, from premRNA splicing and translation to intracellular trafficking of proteins and RNAs. These proteins are thought to use energy from ATP to facilitat
Physical and functional probing of DEAD-box proteins as general RNA chaperones
The encapsulated fungus Cryptococcus neoformans is responsible for life-threatening disease, particularly in the context of compromised immunity, and current therapy is not adequate. Extracellular glycans define the interface between this oppor
GLYCAN BIOSYNTHESIS IN CRYPTOCOCCUS NEOFORMANS
Albino Deletion Complex and Early Mouse Development - ARRA  Cellular differentiation from pluripotency is dependent on global shifts in genomic expression patterns and preservation of inherited transcriptional states throughout development of t
Albino Deletion Complex and Early Mouse Development - ARRA
The prevalence of childhood overweight (CO) has tripled in recent decades, and related health care costs have quadrupled. While lifestyle interventions for CO have produced promising short-term results, a substantial percentage of children rega
CHILDHOOD OBESITY TREATMENT: A MAINTENANCE APPROACH
The major goal of this study is centered on biochemical characterization of molecular mechanisms that regulate thrombin generation and blood clotting pathways with specific aims focused on factor V, HDL and HDL lipids.  Once clinical research a
This renewal proposal explores mechanisms that regulate alternative pre-mRNA splicing in differentiating erythroid cells, focusing on cis-regulatory sequences and trans-acting splicing factor proteins that regulate erythroid stage-specific swit
Red Cell Band 4.1--Developmental Changes in RNA Splicing
Elevation of blood triglycerides, primarily as triglyceride-rich lipoproteins (TGRL), is a known risk factor for the development of atherosclerotic cardiovascular disease and increasingly linked to vascular inflammation. TGRL consist of chylomi
Interactions of Lipoproteins with the Vascular Wall
Title: Dietary Patterns and Risk of Cardiovascular Disease Conventional classifications of saturated, monounsaturated, polyunsaturated, and trans fat incompletely capture the wide heterogeneity across >50 unique fatty acids. In this proposal, w
Dietary Patterns and Risk of Cardiovascular Disease
The longterm goal of our research program is to elucidate the complex neural processing of chemical and mechanical respiratory afferent inputs that underlie the control of breathing by brainstem nuclei in health and in cardiopulmonary diseases.
Pontomedullary Integration of Respiratory Afferents
Atrial fibrillation (AF) is a common arrhythmia and is assuming increased public health importance as the population ages.  The overall objective of this project is to identify novel risk factors for the development of incident AF and to evalua
Atrial Fibrillation: Incidence, Risk Factors, and Genetics
Nonviral Gene Medicine for Hemophilia A -- The goal of this study is to develop a safe, efficient, and clinically feasible nonviral gene therapy strategy for the treatment of hemophilia A. Currently hemophilia A patients are treated with repea
'This project is aimed at developing rational  strategies for the prevention and treatment of lung diseases such as  BPD and ARDS in humans..  Hyperoxia is frequently used in the treatment of pulmonary insufficiency in premature infants.  Howev
Molecular mechanisms of cytochrome P4501A regulation by hyperoxia
High avidity CD8+ T cells are known to be the most effective mediators of viral clearance. Thus understanding how avidity is controlled following viral infection is of critical importance for designing optimally effective therapeutics and vacci
Cellular Immune Response to Respiratory Infection
Light is the most potent stimulus to shift the phase of the endogenous circadian timing system. If properly timed, it is effective in the treatment of circadian phase misalignment as seen in circadian rhythm sleep disorders (e.g., delayed sleep
Adaptation of Circadian Response to Light Treatment
Perception and memory are central to the ordinary but important activities of everyday life. When cooperative interactions between the two processes are undermined by genetic or acquired disorder, by drugs of abuse, by inattention, or by age-re
Visual Recognition Memory: Integrating Perception and Cognition
Two years of support for this project will allow us to perform the experiments proposed in Aims 3 and 4 of the original application. We have been able to complete the bulk of Aims 1 and 2 with support from the American Heart Assoc. This support
The motor cortex of all mammalian species, including humans, contains a gross somatotopic representation of the major divisions of the body, such as hindlimb, forelimb, and face. Within each body part, there are multiple, non-contiguous, partia
Brain function depends critically on the normal operation of synapses and their capacity for modification. An understanding the basic properties of synaptic transmission and plasticity is necessary for illuminating the mechanisms of synaptic dy
Synaptic Vesicle Trafficking in Hippocampal Synapses
Our primary objective is to identify specific gene variants that are related to the formation and rupture of intracranial aneurysms (IA). Our experienced collaborative and highly productive team of Familial Intracranial Aneurysm (FIA) Investiga
Familial Intracranial Aneurysm Study II (FIA II)
Family Study of Stroke Risk and Carotid Atherosclerosis (2-R01-NS040807-07) Tenth ARRA Quarterly Report: October 1st, 2011 – December 31st, 2011  The goal of the Family Study of Stroke Risk and Carotid Atherosclerosis is to identify genetic d
FAMILY STUDY OF STROKE RISK AND CAROTID ATHEROSCLEROSIS
This application is a revised competitive renewal of our grant that is focused on understanding the mechanisms by which mutant huntingtin impairs mitochondrial function. In March 2007 I relocated to the University of Rochester specifically to j
MUTANT HUNTINGTIN COMPROMISES MITOCHONDRIAL FUNCTION
. Of the point mutations (associated with familial AD) within the A¿ sequence itself, most are at positions 21-23, adjacent to the bend region that is essential for association of the two ¿-sheets of wild-type A¿ in fibrils. New solid-state
STRUCTURAL HETEROGENEITY AND COVALENT CHANGES IN BETA AMYLOID FIBRILS
Endothelial cells (ECs) are among the first cells to die acutely after contusive spinal cord injury (SCI), triggering secondary degeneration, including axon and myelin loss.  We showed that i.v. treatments with the Tie2 ligand angiopoietin-1 (A
ARRA Vascular responses as therapeutic targets after SCI
Ischemic injury to the deep white matter is frequently seen in patients with vascular cognitive impairment (VCI). Brain tissue from patients with VCI has matrix metalloproteinases (MMPs) in regions of myelin loss. VCI patients have increased MM
MATRIX METALLOPROTEINASES AND THE BLOOD-BRAIN BARRIER
This proposal has the objective to develop a rational treatment approach for patients with malignant glial-derived brain tumors (glioma). Gliomas and are among the most difficult cancers to treat and typical symptoms include intractable headach
AMINO ACID TRANSPORT AND THE BIOLOGY OF HUMAN GLIOMAS
In multiple sclerosis and other inflammatory disorders of the central nervous system, white blood cells leave the circulation and invade the brain and/or spinal cord, where they cause significant destruction of nerve cells leading to severe dif
CNS INFLAMMATION IN NERVOUS AND MENTAL DISEASE
Developmental Pathways in the Nervous System -- The development of the vertebrate nervous system requires the generation of a large number of different types of neurons, characterized by the specific expression of neurotransmitters and t
Developmental Pathways in the Nervous System
How cells regulate and execute cytokinesis, the final step in cell division, remains one of the major unsolved questions in basic biology. Our long-term goal is the systematic dissection of temporal and spatial control during cytokinesis. It ha
Cell-cell interactions in cerebellar development
Chagas disease, caused by Trypanosoma cruzi, causes nearly 50,000 deaths a year in Latin America and is a concern in the United States (US) because of the high prevalence of T. cruzi in wildlife, presence of competent reduviid vectors, high num
Molecular & Biological Characterization of Trypanosoma cruzi from United States
Wildlife Health Bldg, College of Vet Med
Menisci function to distribution load and increase stability of the knee joint. Both partial and complete meniscectomy have been shown to increase the incidence of osteoarthritis. Meniscal replacement with allograft, synthetic or tissue enginee
Structure and Function of Meniscal Horn Attachments
Several lines of evidence suggest that there is a fundamental relationship between blood flow and secretory function in salivary glands, and it has been hypothesized that salivary hypofunction in diabetic patients results in part from abnormali
BLOOD FLOW AND SALIVARY GLAND FUNCTION IN DIABETES
The focus of this project is the further development of a concise and versatile route for the preparation of differentially substituted heteroaromatics based on the regioselective one-pot polycoupling of polyhalogenated heteroaromatics. The bas
Two million Americans suffer a moderate to severe traumatic brain injury (TBI) each year. In addition, current military action is resulting in a large spike in the number of additional TBI cases. These injuries produce enduring disabilities tha
The Effects of Vitamin B3 on Traumatic Brain Injury
Throughout the World Chlamydia trachomatis is the most common sexually transmitted bacterial pathogen. In areas with poor sanitary conditions C. trachomatis causes trachoma the most common cause of preventable blindness in the World. In symptom
Scanning Chlamydia Proteome for Vaccine Antigens
High Throughput Web-based Image Analysis of Mouse Brain MR Imaging Studies Project Narrative The shapes of structures in the human brain, imaged using MRI, have been associated with a multitude of pathologies and drug-related effects in psychia
High Throughput web-based Image Analysis of Mouse Brain MR Imaging Studies
This SBIR project is designed to develop and demonstrate photoreactive nanofibers for tissue engineering scaffolds. Tissue engineering offers the possibility of aiding regeneration of tissue damaged by disease or trauma and, in some cases, of c
Novel Photoreactive Nanofibers for Bone Regeration Scaffolds
The primary objective of the current research program is to define and characterize the molecular basis for innate resistance and susceptibility of inbred strains of the snail Biomphalaria glabrata to infection by larvae of the human blood fluk
ARRA IMMUNOBIOLOGY OF SCHISTOSOME/MOLLUSC INTERACTIONS
Chemoattractant-induced phagocyte activation is an important mechanism of host defense. In phagocytes, induced activation of the nicotinamide adenine dinucleotide phosphate (NADPH) oxidase leads to robust production of reactive oxygen species (
Molecular Mechanisms of Leukocyte activation
Staphylococcus aureus is the leading cause of community and nosocomially-acquired infectious and toxin-mediated syndromes, some life-threatening that affect patients of all ages.  As a species, S. aureus has become resistant to antibiotics of a
ROLE OF SIGNAL TRANSDUCTION IN RESISTANCE TO CELL-WALL ANTIMICROBIALS IN MRSA
M. tuberculosis (Mtb) is one of the leading causes of death worldwide and claims millions of lives annually. Approximately ~1.7 billion people worldwide are asymptomatically infected with the tubercle bacillus and constitute a major impediment
Role of WhiB3 in M. tuberculosis Virulence
Despite significant efforts, our understanding of clinically relevant mechanisms underlying human pituitary tumorigenesis remains ashamedly meager. My lab has focused on defining the precise molecular mechanisms by which ubiquitous components o
The overall aim of this proposal is to elucidate the mechanism(s) regulating hepatic urea synthesis in case of nonalcoholic fatty liver disease (NAFLD) or metabolic syndrome. The long-term goal is to develop a clinically applicable protocol to
REGULATION OF 15N UREA ISOTOPOMERS PRODUCTION
According to the World Health Organization, obesity in developed countries has reached epidemic proportions. There are globally more than 1 billion adults overweight, with around 300 million of them clinically obese. As consequence, the study o
PROTRH GENE TRANSCRIPTION AND BIOSYNTHESIS BY LEPTIN
The purpose of this Recovery Act-funded Remedial Action Cooperative Agreement is to augment and expedite the current Basin Property Remediation Program (BPRP) by cleaning up an additional 500 to 540 lead and arsenic-contaminated properties in t
American Recovery and Reinvestment Act of 2009 Coeur d' Alene Basin Cooperative Agreeement (STRACA)
This  award will fund portions of the Central City/Clear Creek Superfund Site Operable Unit 4 remedial design, specifically the design of a new water treatment plant.  This plant will treat acid mine drainage from the National Tunnel, Gregory I
ARRA Hazardous Substance Response Trust Fund
The purpose of this predoctoral and postdoctoral research training program is to provide rigorous training in the general fields of social, medical, and economic demography of aging. A major focus is placed on five substantive areas: a) biodemo
SOCIAL, MEDICAL & ECONOMIC DEMOGRAPHY OF AGING
This grant provides funds for training five pre-doctoral students in disease oriented basic neuroscience with an emphasis on aging and age-related neurological disorders.  The program is designed to offer Ph.D. students rigorous and specialized
Basic Neuosciene Training in Age-Related Disorders
This application requests five years of funding for the UTMB training program in Health of Older Minorities. This program was originally funded in 1999 and now supports three pre-doctoral and three postdoctoral positions. In this application we
67 projects were funded (3 have completed construction) and provided principal forgiveness; includes 14 green projects.
This agreement provides funding to the state of Wisconsin for financing the construction of wastewater treatment facilities and associated infrastructure, green infrastructure, nonpoint source projects, estuary projects and program administrati
American Recovery & Reinvestment Act-Clean Water-Wisconsin DNR
This agreement provides funding under the American Recovery and Reinvestment Act of 2009 to the state of Arizona to capitalize its revolving loan fund for the financing and construction of wastewater treatment facilities and associated infrastr
MASSACHUSETTS WATER POLLUTION ABATEMENT TRUST
Award Description: This agreement provides funding under the ARRA of 2009 to the State of Massachusetts to capitalize its revolving loan fund for the financing of construction of wastewater treatment facilities and associated infrastructure, gr
DEPARTMENT OF CONSERVATION & NATURAL RESOURCES
This federal grant provides funding to the State of Nevada to capitalize its revolving loan fund for financing the construction of wastewater treatment facilities, green infrastructure, program administration and clean water related activities.
ARRA grant award to capitalize the West Virginia Clean Water State Revolving Fund for the financing of construction of wastewater treatment facilities and associated infrastructure, green infrastructure and nonpoint source projects. The primary
This agreement provides funding under the American Recovery and Reinvestment Act of 2009 to the state of North Carolina to capitalize its revolving loan fund for the financing for the construction of wastewater treatment facilities and associat
Capitalization Grants for Clean Water State Revolving Fund
COLORADO WATER RES & POWER DEV AUTHORITY
Capitalization Grant for the State of Colorado under the American Recovery and Reinvestment Act of 2009 - Water Pollution Control Revolving Fund.  Funded 12 projects with $15,673,850 of the funding in principal forgiveness; $7,784,856 for green
The Capital Improvement Program is part of the American Recovery Reinvestment Act of 2009.  The grant will address equipment needs of the grantee which are needed to provide state-of-the-art diagnostic and treatment services to a population una
Orange County utilized CDBG-R funds to stimulate the local economy through measures to modernize infrastructure and provide energy efficiency improvements. The funding was allocated in two projects: Project #1: Pine Castle Sidewalks and Drainag
Project #1: Pine Castle Area Sidewalks and Drainage Improvements; Project #2: Energy Efficient Improvements to Orange County Community Centers
Substantial Amendment to Fiscal Year 2008 /2009 Action Plan under the American Recovery and Reinvestment Act (CDBG-R) for Volusia County in the CDBG program funding. CDBG-R projects are: (1) City of Daytona Beach Shores - Public Infrastructure
Community Development Block Grant (CDBG-R)
Program that will create housing to encourage re-population after Hurricane Katrina and prevent blighting and deteriorating conditions withing its residential areas. The purpose of this project is that approximately 7-10 homes will be rehabbed
Katrina Affordable Rebuilding Efforts (KARE)
Funding is intended to address critical employment and economic development needs, particularly through investment in infrastructure that will creat or sustain jobs in the near-term and generate maximum economic benefits in the long-term.
The County will utilize funds from the ARRA in the amount of $234,670 for street improvements (03k)to Belmont Avenue between Burhans Avenue and Haledon Avenue in Halddon, NJ.    Belmont Avenue is a County road that is in terrible condition.  It
03k - Belmont Avenue Street Improvements in Haledon
The Community Development Block Grant Recovery (CDBG-R) program provides funding that have been, or will be, invested in various infrastructure projects in low/mod areas in Monroe County.  The purpose of these projects is to improve existing in
Community Development Block Grant - Recovery.  Funding for home improvements, public improvements, and public facilities to benefit low and moderate income persons and neighborhoods.
Street, Sidewalk, Neighborhood Facility, Residential Rehab Improvements - project locations: Brookhaven, Smithown, Riverhead, East Hampton, Southampton, Southold, Patchogue.
Wake County, NC was awarded $380,721 in CDBG-R grant funds.  The funds will be used for 2 projects and administrative expenses.  The first project is replacement of the HVAC unit in the Cornerstone building,  A day services center for homeless
CDBG-R funding through a competitive process to identify two municipalities that received grants of $500,000 each.  The awards were approved by the Board of County Commissioners to two  sub-grantees the Cities of Maple Heights and Parma Heights
Replace deteriorating concrete sewer pipes with plastic pipe. The process reduces the amount of groundwater that enters the sanitary sewer system, thus reduces cost of wastewater treatment.
Lincoln Street Sewer Rehabilitation Project
COMMUNITY DEVELOPMENT BLOCK GRANT RECOVERY (CDBG-R) funds will invest in 12 projects.  The purpose of these projects to address employment and economic development needs.
Earth Conservancy (03I) & King Ed Econ Dev, (13C)  Fairmont & Ross Twps & Swoyersville Boro St Imp, (03I) Conyngham & Wilkes-Barre Twps & Forty Fort Boro ADA, Hoyt Library Infrastructure, Newport & Plains Twps Demo & Ruth's Place Emer Shelter R
An Industrial Park was developed in Sweeny to provide jobs in a volitile market controlled the petro-chemical industry.  This industrial park will bring light industry to the project area and help offset the unstable unemployment rate in the ar
Sweeny Industrial Park Phase I - Matrix Code 03J - Water/Sewer, Phase II - 03K - Street Improvements, Phase III - 04 - Clearance/Demolition. This project is designed to complete the infrastructure for light manufacuturing businesses.
The Community Development Block Program Recovery (CDBG-R) funds have been invested in several projects throughout the County of Hidalgo. Projects consists of drainage improvements to Hidalgo County Precinct No. 1: Encinal No. 1 and 2 Subidision
This project involves the service connection of approximately 39 houses (approximately 140 individuals) to public water infrastructure for the first time.  The homes are located in Plain View Estates, a primarily low to moderate income neighbor
Home Rehabilitation: Plain View Estates Water Connections
Pursuant to the authority of Title 1 of the Housing & Community Development Act of 1974, HUD will make funding assistance available to the Grantee to provide loan guarantee assistance. Entitlement, Sec 106(b).  The Community Development Block G
Center for Veterans Issues ? acquisition of real property (matrix code 01)
Sandridge Road Overlay & Signalization Project
The Longitudinal Development of African American English and its Role in School Achievement  This research examines the development of African American English (AAE) from childhood through adolescence and its potential impact on literacy acquis
The Longitudinal Development of African American English and its Role in School
CAREER: Testing a Memory-Systems Model of the Expression and Reduction of Racial Prejudice: A Plan for Research and Training
Absolute dates and ages for key geomorphic events in the Midwest U.S. are sorely lacking, mainly because of the paucity of wood in glacial deposits for radiocarbon dating.  This coallaborative research project will address the paucity of geochr
Collaborative Research: Theoretical and Paleonevironmental Implication of Dating and Characterizing Loess Deposits in the Upper Midwest
Logitudinal Investigation of Maternal Influences on Infant Outcomes Mediated by Physiological Investment and Behavioral Care during Lactation in Rhesus Macaques (Macaca Mulatta).
Longitudinal Investigation of Maternal Influences on Infant Outcomes Mediated by Physiological Investment and Behavioral Care During Lactation in Rhesus Macaques (Macaca mulatta)
The pervasive and growing influence of humans on ecosystem functioning and the concurrent decrease in the extent of 'natural' areas have prompted a reconceptualization of the long-term study of ecosystems to include a human dimension. Human sys
Human-Nature Interactions in an Urbanized Island Setting: Hilo and Kailua-Kona, Hawaii as Model Socio-Ecological Systems
Indian Health Service, through an Interagency Agreement with EPA, approved funding for one individual tribal member to correct a sanitary deficiency, which consisted of a sewer lateral that needed replacement due to slope.
This Project will allow the Grand Traverse Band of Ottawa and Chippewa Indians to renovate existing space for the purpose of constructing a dental clinic to be located within the Grand Traverse Band Medicine Lodge. The Grand Traverse Band Medic
Health Center Renovation for Dental Wing
Provide the United States Department of Energy (DOE), Richland Operations Office (RL) with a Program/Project Manager with TRU waste management experience to support the ARRA accelerated scope for RL-013.  Specifically, the contractor shall prov
Acadia National Park- Schoodic Educational & Research Center Building Rehabilitation in coordination with reconstructed roads to make a campus
This project shall consist of the preparation of a Request-for-Proposal (RFP) for Design-Build services for a new maintenance facility in King Salmon Alaska. The Design-Build RFP will consist of schematic design drawings and technical specifica
JOHN G. WAITE ASSOCIATES, ARCHITECTS, PLLC
Title II Design Services Rehabilitation of the Roosevelt Home, Carriage House and Laundry.
Predesign and schematic design services in support of installation of submarine cable through the San Francisco Bay to Alcatraz Island, San Franscisco (cable)
Design services for design development and construction documents for historic stone guardwalls Blue Ridge Parkway.
Gateway National Recreation Area - Replace and Rehabilitate heating system in historic hanger B
In accordance with the terms and conditions of the Indefinite Delivery/Indefinate Quantity (IDIQ) Contract the Contractor shall perform the work of this task for the National Park Service (NPS) as described. The work consists of preparing a dra
BEYER BLINDER BELLE, ARCHITECTS AND PLANNERS, LLP
Architectural & Engineering Services - Rehabilitate Arlington House, Outbuildings and Grounds, Phase 2b:  Construct New Comfort Station.  BBB is to assist the NPS NCR with gaining approval of the CRA and NCPC for the design of the Comfort Stati
surface asphalt overlay of tour roads and parking areas at Guilford Courthouse National Military Park.
Design Development and Construction Documents - Rehabilitation and Expansion of Visitor Center
Predesign Services, Evaluation of Septic System
AtlantiCare Health Services (AHS), located in Atlantic County, New Jersey is a 330 Health Care for the Homeless Federally Qualified Health Center is requesting Capital Improvement Project funds in the amount of $364,170 in order to provide1964
Capital Improvement Program. The purpose of the program is the implementation of the EHR system and renovation/alteration of the existing space in readiness of EHR implementation. The project is expected to facilitate an efficient and effective
BATON ROUGE PRIMARY CARE COLLABORATIVE, INC.
The original purpose of these funds was to purchase the Plank Road Plaza Medical Facility. However, following a period of negotiations, it was decided that this facility would not be suitable for BRPCC. A change in grant type was made and appro
Sonoma Valley Community Health Center (SVCHC) submitted three projects to be addressed with the CIP Funds:   1) Implement a Certified EHR/Practice Management System (PMS):  Over the last 2 years, SVCHC has been preparing for the implementation
The CIP funding will allow for Community Health Services to repair and renovate both the Main Office and the Fremont Family Practice office. The Main Office has three areas that require significant repair. First, the roof on the older section o
Grant was awarded for renovation and additional space in the Stedman Wade Dental Clinic in Stedman, North Carolina.  Additional operatories and administrative space were needed to accommodate the rural population of Stedman and its surrounding
The capital investment project award is to implement a new telephone and electronic medical records sytem to increase operational efficiency and increase patient satisfaction.
Capital Improvement Program -The purpose of this award is to provide funding for the renovation of space in the Metta Health Center of Lowell Community Health Center.  This renovation will result in the addition of exam room and behavioral heal
MEDICAL RESOURCE CENTER FOR RANDOLPH COUNTY, INC.
Building Expansion and Implementation of EHR
LACHC CIP funds will be used to increase capacity to provide primary and preventive health care services across our comprehensive service areas to all lifecycles. Joshua House and Pico Aliso will implement alteration/repair/renovation projects
ARRA Capital Improvement Project.  The HOMES program delivers health care to homeless individuals and families in Dallas County through the use of four mobile medical units and a fixed site clinic. The mobile units range in age from three to th
SAINT CROIX REGIONAL FAMILY HEALTH CENTER
ARRA Capital Improvement Program award for St. Croix Regional Family Health Center provides for two projects: 1.) Certified EHR Project to implement electronic medical records, and 2.) Facility Renovations to replace flooring on both the 1st an
ARKANSAS VERDGRIS VALLEY HEALTH CENTERS INC
Plans to increase clinical services through the  addition of over 3000 square feet, including six exam rooms, 2 mental health rooms and 3 dental operatories.  All admin offices and clinic facilities will be in one building. Currently we are in
Sunrise Community Health (Sunrise) Electronic Health Record (EHR) proposal included bringing safety net partners from the community onto Sunrise's EHR.  Sunrise is accomplishing this goal with two modifications:  1.  Implementing wireless acces
KO'OLAULOA COMMUNITY HEALTH & WELLNESS CENTER, INC
The Hau?ula Clinic Expansion Project  In December, 2008 the Ko?olauloa Community Health and Wellness Center (KCHWC) established a new clinic in Hau?ula next to our administrative offices and also relocated the existing Kahuku clinic onto the gr
ARRA Capital Improvement Program- Neighborcare Health (previously Puget Sound Neighborhood Health Centers) received funding for two projects. The first is a Multi-Site Equipment Upgrade that will replace worn and outdated equipment across our c
Systems Enhancement Project (SEP).  The goals for the SEP project are to increase access to health care (medical and dental) for farm workers, improve security at the health center in Moorhead, and reduce expenses for telephone services. Access
ARRA Funding for Four Capital Improvement Projects -  1 - A/R/R - Borrego Medical Foundation Renovation Project.  Renovate the flooring at our Borrego Springs clinic.  2 - Certified EHR-Related purchase - EMR system wide project.  Purchase the
The United Community Health Center of Storm Lake (UCHC) became funded as a 330(e) grantee in March of 2006. UCHC serves Buena Vista and Sac counties of northwestern Iowa. UCHC operates a single, freestanding, medical facility in the City of Sto
The current method of calling and notifying patients of their appointments, clinic closures and other information is handled by the office staff walking into the waiting room and calling for the patient in question.  Due to the campus-style lay
Health center renovation and certified-EHR purchase.
The purpose of this grant is to enable community health centers and federally qualified health centers such as the Matilda Theiss Health Center (MTHC) to improve facilities in anticipation of an increase in demand for services during the econom
will ensure that the Erie Humboldt Park Health Center remains a major source of health services for the community.  The current building where the health center is housed is in need of urgent repairs to the mechanical, electrical and plumbing
CENTRO DE SERVICIOS PRIMARIOS DE SALUD DE PATILLAS INC.
Grant Name: Patillas Capital Improvement Program Purpose:Increase the limited spaceof Pharmacy,Immunization and Pediatrics. Buy the equipment and make the necessary adjustments to the infrastructure of the computerized system for the Electronic
The Seattle-King County Department of Public Health’s Health Care for the Homeless program has completed implementation of a health center Capital Improvement Project (CIP) award that included projects designed to improve access to and qualit
Embedded in the CIP proposal are renovation projects which address much need building renovations including replacement of leaking roofs; replacement of inadequate and inefficient heating and cooling systems; re-paving of parking lots which are
The Capital Improvement Program grant for the The Lake County Health Department and Community Health Center (LCHD/CHC) consists of three projects: 1. A Certified Electronic Health Record-Related Purchase/NextGen Server; the LCHD/CHC will increa
This report is for the previous quarter and this quarter combined,#2 and #3. ARRA Capital Improvement Program Grant #C81CS13859 funds in the amount of $293,820 were awarded to Ashland Community Health Center on 6/25/2009 and were utilized for t
CIP Funding, awarded to Chota, was redirected during the summer of 2010 to allow for the purchase of a new electronic medical records system. The original Madisonville Renovation and Equipment Project and the Tellico Construction Project, were
Chota Community Health Services:  Madisonville Renovation and Equipment; Tellico Renovation and Installlation of a Electronic Medical Records System
Spectrum Health Services proposed three major projects in response to the Capital Improvement Program initiative.  The first project is an Alteration/Repair/Renovation project in which  Spectrum proposes to use the CIP funds to make renovations
MOUNT VERNON NEIGHBORHOOD HEALTH CENTER, INC.
The CIP will provide needed construction of a new facility for Comprehensive Community Development Corp, d/b/a Soundview HealthCare Network (SHCN) at its flagship site, Soundview Health Center (Soundview). The new construction will better accom
FAMILY HEALTH CENTERS OF SAN DIEGO, INC.
Family Health Centers of San Diego (FHCSD) will address the community’s immediate need for expanded access to affordable healthcare services by relocating and expanding its City Heights Family Health Center (CHFHC).  CHFHC is currently locate
CIP award funds the Construction of a 10,500 sq.ft. Medical Facility and Alteration and Renovation of the existing San Juan Clinic. The strategic plan for this ARRA funding is to build a 10,500 sq ft building to move our Pharmacy, OB/GYN, MIS a
By building a new facility for the Vermillion-Parke Community Health Center, the quality of care provided by the facility will increase and serve the meet the needs of the community. The proposal will address our community?s immediate needs of
Capital Improvement Program (CIP) Friend Family Health Center, Inc (FFHC) The purpose of the award is to substantially enhance the delivery of health care and social support services to the community.  FFHC realizes that there must be adequate
ARRA-Capital Improvement Program.  Funding was awarded to expand Sea Mar's medical and dental clinics in Marysville and Mt. Vernon, WA, and to renovate its medical, dental and outpatient clinic in Puyallup, WA.  Sea Mar submitted a Prior Approv
ARRA-CIP:  NOGA for this award was initially delayed.  Grant was officially accepted by the city of Manchester on October 6, 2009; when  CIP start up ensued.  CIP project #1 covered Alterations & Renovations of the HCH Manchester clinic space l
Renovation of the HCH Manchester Shelter Clinic space at New Horizons Shelter
Capital Improvement Program (CIP) - Electronic Health Records, Modular Building, and Equipment Only projects
SETTLEMENT HEALTH AND MEDICAL SERVICES, INC.
Community Health Center, Inc's (CHC) CIP grant award will allow the following strategic objectives to be met by the organization:   A.	Electronic Health Record - CHC will purchase and implement an electronic health record that will be used by a
BELINGTON COMMUNITY MEDICAL SERVICES ASSOCIATION
The CIP will enhance HCCC's ability to serve the medical, dental, mental health and pharmaceutical needs of the highest risk residents of Muskegon County.  One aspect of the CIP will be to expand and renovate the medical and mental health area
CDBG 2008 Recovery Act Amendment- Road Construction
The City of Newburgh Planning & Development Department, as a part of the CDBR-R funding, developed a Housing Affordability Program that includes Sealed Bid Financing program and a Home Rehabilitation Program.  To date, the City has disposed of
Tier II Emergency Home Repair, $75,000. Sub-recipient: Mountain Housing Opportunities (MHO). Extensive repair of five homes owned by very-low and low-income, special need households. Maximum investment per home is $15,000. Repairs facilitated e
CDBG-R activities include a wide variety of community development projects directed towards housing, neighborhood revitalization, economic development, and the provision of improved facilities and services.
Community Development Block Grant Entitlement Program -The program focus is to develop additional housing opportunities for low to moderate income households within the communty along with economic development that spurs job creation.
Community Development Block Grant Entitlement Program
Community Development Block Grant ARRA Entitlement Grants (CDBG-R)(Recovery Act Funded).  Funds will invest in the rehabilitation of single-family, owner-occupied housing; rehabilitation of Burton Street Apartments transitional housing for home
Community Development Block Grant ARRA Entitlement Grants (CDBG-R) Rehabilitation
Funds will be used to make safety improvements to public housing units. Upon completion of a deck replacement project, the units will be much safer for the residents. Funds will also be used to replace toilets in the Town's public housing commu
Funds will be used for 3 proejcts: Construction of Infrastructure (Habitat for Humanity); a water conservation project (public housing); and rehabilitation (public housing).
The Community Development Block Grant ARRA Entitlement Grant is for the revitalization of neighborhood economic development and improving community facilities and services.  The award is expected to facilitate the improvement of various City st
Program is focused on six activities, plus administration of a foreclosure rescue program, infrastructure, exterior repairs and rehabilitation collaboration, rental rehab, and new construction of a senior center, designed to stimulate local pro
Funding enables the city of Bowling Green, Ohio to implement added community development and housing programs for low and moderate income persons.
Loan Program for Residential Renewable Energy Technologies and measures to be utilized for installation of Residential Renewable Energy Technologies that could include:  Solar Hot Water Systems, Solar Power Systems, Solar Heating Systems, Resid
Loan Program for Residential Renewable Energy Technologies
Construction of curb cuts for handicapped accessibility in accordance with the latest ADA requirements in  primarily residential neighborhoods.
CDBG-R Program for infrastructure improvements
Upper Darby CDBG-R Storm Sewer reconstruction
Funds from this award will be used to enhance the Municipality of Penn Hills existing CDBG Program. We will be funding the following activities: YMCA Scholarship Program LPCC Food Pantry Jefferson Manor Food Pantry WPHCA Neighborhood Beautifica
People/Families with of People with Disabilities
CDBG-R funds will provide for the rehabilitation of 2 to 3 substandard, single family, owner-occupied housing units for compliance with HUD Section 8 Housing Quality Standards.
Millcreek Township Single Family Housing Rehabilitation Project
The City of Greenville, SC was able to focus it's CDBG-R funds on two primary activities:  Activity Name:Tindal Community Residence Renovation - Greenville Mental Health $125,373.29 in funds was used for the renovation of the 8-bed Tindal Commu
Community Development Block Grant funds provided for CDBG eligible projects focused on neighborhood stabilization and job retention/creation.
Community Development Block Grant Recovery Program
This award is a Community Development Block Grant - Recovery (CDBG-R) which the City of Murfreesboro is using to reconstruct substandard housing.
Community Development:  The Mission East Dallas CDBG-R activity will assist those most impacted by the recession; uninsured low-income residents.  This activity will offer acute medical and dental care to uninsured low-income residents.  Patien
Funding will be used for South Waco Community Center Improvements to include renovations to create multipurpose community meeting spaces and two classrooms. The area will house the daily senior group meeting, periodic community and neighborhood
Community Development Block Grant ARRA Entitlement Grants(CDBG-R)(Recovery Act Funded)
Community Development Block Grant Recovery (CDBG-R) Infrastructure - Eastside Waterline Replacement Project - Purpose of program is replacement of failing waterlines in a low-income residential neighborhood that directly affects adjacent househ
CDBG-R Eastside Waterline Replacement Project (Matrix Code 03J)
The Day Labor Center (DLC) is one of the City of Plano's public facilities and assists hundreds of unemployed and/or under-employed individuals in obtaining contract labor jobs.  On average, 250 individuals come to the DLC daily for employment.
City of Plano Day Labor Center Improvements
CDBG-RA funds in the amount of $66,501 to do two rehabs.
CDBG ARRA Entitlement Recovery Act Funds
Frisco Housing Authority Unit HVAC and Electrical Replacement
funds will be used to stimulate the current economic situation by creating/retaining jobs, principally to low-to-moderate-income individuals, thus increasing their economic opportunities. funds must also meet one of HUD's national objectives fo
(1) 14A Rehabilitation: Single-Unit Residential -Proyecto Azteca, (2) 05M - Health Services - Dentists Who Care
COMMUNITY DEVELOPMENT BLOCK GRANT-RECOVERY FUNDS IN THE AMOUNT OF $135,573, SUPPLEMENT TO 2008 CDBG ENTITLEMENT FUNDS.
CDBG - ARRA funding to the City of New Braunfels
The funding will be used to resurface the asphalt parking lot at the Southwest Community Center, provide drainage improvements to Karrh and Scott Joplin Parks, repair the driveway at Karrh Park and dredge the pond at Karrh Park. These improveme
In accorandance with CDBG-R regulations, the City will make $1,370,992 of ARRA funds available in support of the following programs:                                                     Chesterfield Heights Resource Center -  $750,000 Traffic Si
land acquisition, infrastructure improvements, loan loss reserves, micro-enterprise assistance.
Community Development: CDBG-R Recovery act funding used for sidewalk, curb and gutter construction on E. Gay St., Harrisonburg, VA.
Community Development Block Grant-R Grant Avenue Sewer Extension- Provides for the design and construction of 1,400 linear feet of sanitary sewer main along Grant Avenue between Berkeley Street and Orchard Street. The project also requires the
CDBG-R funds will be directed to infrastucture activities (street repairs, curb & sidewalk repairs) in the city of Charleston, that will provide long term economic benefits and will provide or retain construction jobs.
Community Development Block Grant Recovery Funds.
The Municipality is proposing the rehabilitation of existing deteriorated sidewalks at Margarita, Boquerón and Las 35 Communities. Safe, pedestrian-friendly neighborhoods are a priority for our community.  Using CDBG-R funds the Municipality o
Community Development Block Grant ARRA Entitlement Grant (CDBG-R) Recovery Act Funded.
Utilities and infrastructure is the focus of the project. Utilities include gas, electric, and telephone/cable lines throughout a new 44 site sub-division on the reservation. Infrastructure includes water lines through a portion of this sub-div
Keweenaw Bay Indian Community Early Childhood Education Center
Installation of water meters on approximately 288 housing units
Indian Community Development Block Grant-Preserve and create jobs, promote, economic recovery, assist those impacted by the recession, and invest in transportation, environment and infrastructure that will provide long term economic benefits
CDBG-R funds will be used to provide low interest loans to businesses wishing to expand or relocate to east Montgomery Co., TX.  In exchange for low interest loans, businesses agree to hire low income local residents, per standard procedures se
Economic Development Business Loan Program
Street resurfacing of Red Fox Road. The scope of work has been expanded to include an additional mile of resurfacing of Red Fox Road.  This additional mile will be paid by the County's general fund.
Street Resurfacing Project/ Red Fox Fox Road
Community Development  Fund staffing, travel, materials and supplies to oversee and operate the County's Community Development Block Grant ARRA Entitlement Grant (CDBG-R).  Fund three public works and infrastructure improvement activities.  Tra
Reedley Central Area Street Improvements, Tranquillity Park Playground Equipment, Kerman California Avenue Storm Drainage Improvements
CDBG-R funds will mostly be used for the removal of architectural barriers at various barriers at various public facilities throughout the County of San Luis Obispo.
Community Development: CDBG-R funds will be used to preserve and create jobs and economic recovery by investing in infrastructure and energy efficiency.
CDBG-Recovery Program helps to stimulate the economy through measures that modernize the Nation's infrastructure, improve energy efficiency, and expand educational opportunities and access to health care.
Community Development Block Grant ARRA Entitlement Grant
AID Rehab, Monroe St. Reconstruction, Ecker Center Elevator Upgrade
CDBG-R funded Housing Rehab, Youth Development, Crime Prevention,  Concentrated Code Enforcement, and Planning/Admin  For additional detail see activities description below
Community Development.  Specifically, funds will be used to rehabilitate 150 units of affordable rental housing for low income families in Annapolis, Maryland.  Funding Agency Code*
Annapolis Gardens/Bowman Court Redevelopment Project
This grant will assist in converting a former office building into a domestic violence shelter for abused women and their dependent children.
Community Development projects benefitting low and moderate income households.
Community Development activities including Public Facilities Improvements, ADA Recreational Improvements and Downtown Revitalization
Community Development Block Grant Program - Recovery
Preserve jobs and promote economic recovery by investing in infrastructure that will provide long term economic benefits. We anticipate the retention of 33 jobs and improvements to transporation, accessiblity and quality of life for 100's of re
Community Development Block Grant Recovery Act funding to be used for economic stimulus through the creation of permanent jobs.
The Community Development Block Grant Recovery Program (CDBG-R) will fund the following projects:Project 1-Mobile Home Park Resident Relocation-assistance to residents of mobile home park who need to move due to blighting/condemning influences.
Demolition Economic Development, Public Facilities
Funds are to be used for an Revolving Loan Fund (RLF) program, Eastlake Senior Center roof replacement, and the creation of a Special Improvement District (SID) to finance energy efficiency projects.
Machine Tool (Metal Forming Types) Manufacturing
The County of York has been authorized to receive $702,477 in Community Development Block Grant Recovery (CDBG-R) Program funding. The American Recovery and Reinvestment Act of 2009 (ARRA) appropriated $1 billion in CDBG funds to states and loc
$276,897.00 in CDBG-R funds be used to fund the following three community development activities in the amounts identified below:  Dixon-Robinson Water Line (Arlington, TN)	 $152,450.00 West Street Sidewalk Improvements(Collierville, TN)$71,897
CDBG-R; seven public works projects improving water and sewer systems and street and drainage systems for Urban Tarrant County and the entitlement cities of Euless and North Richland Hills. North Richland Hills will also use funds to rehabilita
The U.S. Department of Housing and Urban Development has allocated an additional $2,919,475 in Community Development Block Grant funds to Harris County as part of the American Recovery and Reinvestment Act of 2009 (Recovery Act).  This addition
1. HCWCID 36 N. Zone 1 Wastewater Improvements; HCWCID 36 N. Zone 2 Wastewater Improvements; HCWCID 36 S. Zone Wastewater Improvements.
The Community Development Block Grant Recovery (CDBG-R) Program funds will be used to complete emergency and minor housing repairs for low-income homeowners in Henrico County and to complete improvements related to safety and ADA-accessibility
This award initally provided funding for three shovel-ready infrastructure projects.  These high-priority need projects are located in Rockford, WA; Fairfield, WA; and Carnhope Irrigation District in Spokane Valley, WA.  The Town of Rockford, w
Community Development Block Grant funds for park improvements, youth shelter improvements, handcaped accessability improvments to community center, and repair and replacement of failed septic systems of low income homeowners.
CDBG funds for improvments to low income communitites and households.
This research project develops analytical/mathematical and computational modeling tools for evaluating the fit between theoretically posited syllabic parses and experimental data on the timing or coordination of speech movements registered from
Collaborative Research: A Pilot Study of the Spatiotemporal Scales of Diversification in the Pandora Moth/Ponderosa Pine System Using Dendrochronology and Evolutionary Biogeography
The award provides funding to the UG to be used to conduct community wide assessments at potential brownfields sites contaminated with hazardous substances. Funds will also be used for public outreach in the planning process.
Unified Government of Wyandotte County, Kansas City, Kansas Brownfield Hazardous Assessment
BLACKFEET TRIBE OF THE BLACKFEET INDIAN RESERVATION MONTANA
THE AWARD WILL SUPPLEMENT AND SUPPORT THE COMPLETION OF THE BLACKFEET COMMUNITY WATER PROJECT-PHASE 3 WATER MAIN FROM THE WATER TREATMENT PLANT CONSTRUCTED NEAR THE LOWER TWO MEDICINE RESERVOIR TO THE COMMUNITY OF BROWNING.
EPA provided I.H.S. $1,033,610 of Clean Water Act Indian Set Aside funds through Interagency Agreement DW-75-95765901-0 for this project.  Project scope: INSTALL NEW FOUR CELL AERATED LAGOON TO THE WEST OF EXISTING FACILITY located at Crow Agen
Recent progress in podocyte biology suggests that glomerular capsular cell, namely glomerular parietal cells have the potential to contribute to podocyte regeneration/renal repair after kidney development concludes. My results derived from proj
Role of Stem Cells in Renal Repair after Inducible Epithelial Ablation
Administrative supplement to parent grant:  Genome-wide promoter methylation profiling of glioma  Since the beginning of the award in 9/1/2008 for the parent K-award entitled Genome-wide promoter methylation profiling of glioma, progress has be
GENOME-WIDE PROMOTER METHYLATION PROFILING OF GLIOMA
BRCA1 mutations trigger high penetrance breast carcinogenesis. Most such tumors are triple negative/basal-like. How loss of BRCA1 function elicits breast cancer development and why it does so at markedly high rates and, often, at abnormally you
Title: Induced pluripotent stem cell differentiation along neuronal, germ cell, and hematopoietic lineages.  This supplemental funding was requested to accelerate the pace of research towards eventual clinical use of stem cell lines by providin
CONTROL OF MULTILINEAGE HUMAN ESC DIFFERENTIATION
The Nebraska Research Network in Functional Genomics has two major components, the undergraduate campuses located throughout the State and the research campuses located in Omaha and Lincoln. On the undergraduate campuses, INBRE will support 24
Nebraska Research Network in Functional Genomics
This administrative supplement supports a new pilot funding program in Translational Cancer Medicine that will effectively leverage scientific activities within the research programs of the Kimmel Cancer Center.  As with many Cancer Centers, a
Tfiis is a K99 to ROO transition application which seeks further support for studying the association of four opioid receptor genes (0PRM1, 0PRD1, 0PRK1, and 0PRL1) and four opioid peptide genes (POMC, PDYN, PENK, and PNOC) genes and substance
Association and Function of Opioid Receptor GeneVariants to Substance Dependence
This fund is an ARRA administrative supplement to Fund #50437N entitled, 'Behavioral and MRI Evaluation of Prenatal Alcohol Exposure.' The supplement will provide support for an undergraduate college student who will support the research effort
ARRA: Behavioral EEG and MRI Evaluation of Prenatal Alcohol Exposure
Mechanisms of GABA-A receptor plasticity in alcoholism Alcohol abuse represents a significant problem in our society. Chronic intermittent ethanol (CIE) treatment of rats (60 doses of intermittent intoxication and withdrawal), encompasses all o
MECHANISMS OF GABBA RECEPTOR PLASTICITY IN ALCOHOLISM
This is an award for equipment to supplement with the prime research award program described by the award title. We have requested a sole-source purchase and are awaiting Dept. Purchasing approval.
The Role of Alcohol in HIV Therapy Hepatotoxicity
Title: Physiological Factors in Hyperthermia.   Description:  The focus of the supplemental research will be to use our newly commissioned small animal conformal radiation research system (SACRRS) to apply simultaneous conformal radiation thera
Although treatment has steadily improved in the past 20 years for children with high-risk metastatic neuroblastoma (stage 4), only 40% of these patients survive long-term.  Our overall goal is to improve survival for these children. Problem: It
Clinical Correlative Studies of Neuroblastoma
ARRA Admin Supp (NOT-OD-056) for 2R01 CA093897-05A1; Myeloma-Microenvironment Interaction Dynamics. Multiple myeloma, a malignancy characterized by accumulation of monoclonal plasma cells in the bone marrow, is associated with severe osteolytic
ARRA Admin Supp (NOT-OD-056) for RO1 CA134522-01, Potentiating Natural Killer Cell Anti-Myeloma Effects.  Multiple myeloma, a malignancy of plasma cells, is a major health issue in the United States, with 100,000 people currently living with th
ARRA Admin Supp (NOT-OD-056) for RO1 CA134522-01, Potentiating Natural Killer Cell Anti-Myeloma Effects
Administrative supplement to an active NIH Research Grant entitled 'Molecular Determinants of Oral Tongue Cancer Metastasis' This is an application requesting administrative supplement, for equipment, to an active NIH Research Grant entitled 'M
MOLECULAR DETERMINANTS OF ORAL TONGUE CANCER METASTASIS
, we created, manualized, and pilot tested a unique contingency-management (CM) intervention that combined abstinence-based voucher incentives with contingency management training for parents. A small randomized, clinical trial provided encoura
Behavioral Treatment of Adolescent Marijuana Use
Reducing Sexual Risk Behaviors among Rural African-American Cocaine Users.  This project will utilize a grounded theory approach to conduct a developmental formative evaluation to examine the local characteristics of organizations, providers, a
Reducing Sexual Risk Behaviors among Rural African-American Cocaine Users
This Competitive Revision of my currently funded RO1 (DE DE012459-12) is submitted in response to, and in accordance with Notice Number NOT-OD-09-058, titled, NIH Announces the Availability of Recovery Act Funds for Competitive Revision Applica
The renal preglomerular microvasculature is critically involved in achieving the homeostatic functions of the kidneys, including the regulation of Na+ and H2O excretion. The primary Na+ retaining hormone, angiotensin II (AngII), acts via AT1 re
Tyrosine Kinases In Renal Vasoconstrictor Signaling
Studies will exploit the power of Drosophila genetics and the relative ease of administering toxins to flies to determine how genes and the environment may interact to promote the death of dopaminergic neurons and to inhibit the function of mit
ENVIRONMENTAL TOXIN INTERACTIONS WITH GENETIC RISKS FOR PARKINSON'S DISEASE
The objective of the NIH Grant Number R01EY009859 is to identify the genetic basis of age-related Maculopathy (GARM). This project is committed to the prospective study of genetic, environmental and early clinical risk factors for the developme
Funds were provided to purchase a specialized microscope (total internal reflectance microscope) that will be used to visualize the movements of single molecules or single synaptic vesicles.  We will use this microscope to analyze the mechanism
PROJECT SUMMARY: Proper functioning of the cell cycle and its regulation in response to both internal and external stimuli is essential for the normal growth, division, and differentiation of cells and tissues. Major control over cell cycle pro
Myxococcus xanthus is an established model bacterium and hallmark for microbial social behaviors, which has provided valuable information about socio-microbiology for decades.  Our laboratory has been supported by NIGMS for the past 12 years to
INTERCELLULAR SIGNALING IN MYXOCOCCUS XANTHUS
To understand normal development and differentiation, it is necessary to determine the mechanisms by which cells initiate new programs of gene expression and promote formation of specific cell lineages.  Typically, this involves activation of g
Transcription Factor Function in Chromatin
This is a request to NIH for a Recovery Act Administrative Supplement  to accelerate the tempo of research  currently supported by  5R01GM056766-08, which is titled Computer Simulations of Protein Aggregation. The supplement would be used to hi
Computer Simulations of Protein Aggregation (See 1998-1850)
The overall goal of the project is to characterize the structures and interactions of the BCL-2 family proteins, the principal regulators of the mitochondrion-dependent pathway for programmed cell death or apoptosis. Their opposing pro- or anti
Structures of membrane-bound Bcl-2 apoptotic proteins
Signaling through the RAF-MEK-ERK1/2 MAP kinase pathway is critical for a wide variety of biological processes in both normal and disease states. Our long term goal is to determine mechanisms underlying regulation of this pathway and identify t
Adhesion Regulation of ERK Trafficking to the Nucleus
Toll-like receptors (TLRs) are the key sensors of microbes in innate immune cells. TLR activation is central for host defense; nevertheless dysregulation of TLR activation might lead to acute or chronic inflammatory diseases. Thus, the extent a
Ubiquitination of Toll-like receptor signalsome
Human cytochrome P450 (CYPs) are essential enzymes involved in clearing drugs and foreign chemicals from the body. The last decade of cytochrome P450 research suggests that many P450 proteins undergo induced fit in response to ligand binding an
Structural Basis of Cytochrome P450 2A13 Activity
Our overall goal is to identify transcription factors (TFs) that can bind C. elegans gene promoters. This will further our understanding of the networks that control gene expression and to delineate the regulatory genomic code. In the first yea
Identifying Transcription Factor Binding Sites in the C. elegans Genome
Hsp90 is a unique chaperone that is essential in eukaryotes and that helps to produce and maintain the active state of a select set of biologically and medically important substrates/clients including many signal transduction proteins. Through
Conformational Cycles of Molecular Chaperones
Interventions to promote continued abstinence and the avoidance of risky sexual behaviors are far more likely to be successful than attempts to alter established patterns of high-risk sexual activity. The proposed project is a randomized, contr
Comprehensive Elementary School Risk Prevention
This focus of this award is two-fold. First, funds will be used to support the salary of a postdoctoral fellow, who will help to coordinate the experiments described in the proposal. Second, funds will be used to purchase two new eye trackers f
Alveolar destruction and pulmonary fibrosis are juxtaposed in COPD and pulmonary fibrosis. Surprisingly, the relationships between these responses and the mechanisms that destroy alveoli while simultaneously nducing fibrosis have not been defin
Genetic Factors controlling effector function of TGF-Beta in COPD and Fibrosis
Non-receptor tyrosine kinases have been implicated in protection of the ischemic myocardium, but the intracellular sites of action, and the molecular identity of the specific tyrosine kinases responsible for the effects attributed to pharmacolo
NOVEL MECHANISMS OF TYROSINE KINASE SIGNALING IN HEART
Control of HSC proliferation and migration by the transcription factor EGR1 - EGR1 (Early Growth Response 1) is a well-known transcription factor of the immediate early gene family. My lab recently discovered an unexpected and intriguing role f
Control of HSC proliferation and migration by the transcription factor EGR1 - EGR1
Title - Telemedicine-Based Collaborative Care to Reduce Rural Health Disparities      Description - To interpret the estimated relative effectiveness of the two models of collaborative care, it is necessary to know how well the care manager pro
Telemedicine-Based Collaborative Care to Reduce Rural Health Disparities
Stroke is a major cause of morbidity and mortality in the United States and presents challenges in the development of disease prevention strategies. Deprivation of nutrients and oxygen supply to brain cells produces immediate death in the most
Mitochondrial Ion Channels in Hypoxic Neurons
Glutamate-receptor ion channels (iGluRs) participate in brain functions that range from fast synaptic transmission to activity-dependent changes that underlie certain forms of learning and memory. These receptors are also implicated in a variet
Single Channel Properties and Structure of Glutamate Receptors
The proper function of axons, the output of neurons, is critical to the proper functioning of the brain, particularly the cerebral cortex. Numerous neurological disorders result from disruption of axonal function. Our study will use newly devel
Properties of Axons and Synaptic Communication in the Neocortex
The ARRA Summer Supplement grant was awarded to hire medical, undergraduate and high school students to perform research directly related to the parent R01 NS38992 grant.   Three students were identified to be recipients of this award: Snow T.
PATHOPHYSIOLOGY OF DEVELOPING DYSPLASTIC HUMAN CORTEX
This country lacks a cohesive, informative surveillance system for vascular disease that can provide insights into national patterns of stroke and reveal national trends over time. Stroke is a major public health problem in the United States. I
Stroke hospitalization in the elderly with medicare FFS (SHEFF) study
This ARRA administrative supplement will fund pre-clinical work that will lead up to a human clinical trial for HIV-associated cognitive decline testing the peptide cytokines erythropoietin in conjunction with insulin-like growth factor-I.  We
Erythropoietin PLUS IGF-IN NEUROPROTECTION FROM AIDS
To determine how fl-mhtt expression in CPNs may influence cell autonomous gene expression in the cortex and non-cell-autonomous gene expression in the striatum, we will profile cortical and striatal gene expression from BACHD, BE, and WT contro
CONDITIONAL MODELS: NON-CELL-ANTONOMOUS TOXICITIES IN HD
Neural progenitor cells (NPC) are present throughout life and replenish neurons and glia (astrocytes and oligodendrocytes) through neurogenesis, a process that requires proper migration, proliferation and differentiation of NPC. Neurogenesis ap
SDF-1 and Neurogenesis in HIV-1 Associated Dementia
This award is designed to investigate the role of protein kinase C epsilon (PKCe) in the  antiadrenergic action of adenosine.  The antiadrenergic action of adenosine via adenosine A1 receptors limits the responsiveness of the heart to beta-adre
The goal of our studies is to determine the functional role of Runx2 expressed by vascular smooth muscle cells in regulating vascular calcification. In the parent grant, we have designed complementary studies using cultured vascular smooth musc
MOLECULAR SIGNALING IN OXIDATIVE STRESS-INDUCED VASCULAR CALCIFICATION
, we proposed to disover and validate serum protein biomarkers for metastatic oral tongue cancer. Development of these biomarkers will lead to clinical tools for accurate detection of metastasis and improved treatment decision making for patien
QUANTITATIVE SALIVARY PROTEOMICS FOR HUMAN ORAL CANCER (R03)
The $80,000 administrative supplement to accelerate work on two specfic taskd required to achieve Specific Aim 2 of our original grant request: 1. to create image processing software for automated analysis of AFM images and 2. to implement modi
NOVEL HIGH-THROUGHPUT TECHNOLOGY FOR GENE EXPRESSION PROFILING BASED ON AFM
In order to continue to enhance and expand our goal of introducing authentic problem based learning into K- 12 schools, the NCRR SEPA Building Bridges to Health Science Literacy (BBHSl) program at the University of Tennessee Health Science Cent
Building Bridges to Health Science Literacy
Support is requested for three undergraduate students and a high school science teacher to participate in summer research projects on one of the principal themes of the parent grant, namely the role of SLC26A6 and related transporters in the in
Roles of SLC26A6 in Renal NaCL Transport and prevention of OXalate Urolithiasis
Mediomics is  requesting funds to purchase a new fluorescence plate reader with the capability of performing time-resolved flourescence experiments. With this new instrument, we will be able to transfer the technology co-developed in Dr. Heyduk
apid homogeneous antibody-based detection of proteins
Biomedical research continues to expand the use of detailed atomic-scale structure in developing a detailed understanding of the molecular basis for life and for disease. Tools for the identification of means for intervention at the molecular l
APPARATUS FOR NMR SPECTROSCOPY OF ENCAPSULATED PROTEINS
HCV NS3 and NS5A: Biochemical Mechanisms and Biological Functions;  The long-term goal of this project is to determine the mechanism of RNA replication of HCV.  The immediate focus of this proposal is on those proteins that bind and manipulate
HCV NS3 and NS5A: Biochemical Mechanisms and Biological Functions
This supplement requests support for an additional method, molecular electron microscopy (EM), to be included in the studies involving all three aims of the prime.
Recombinant Amelogenin Matrices for Aopatite Nanofibers
The timeline for finishing the construction of the entire 250 antisense clones in E. coli is the middle of funding period 3 (Y3), while the timeline for completely developing the target identification assay is by the middle of funding period 4
Antibacterial Target Identification Using Expression of Essential Genes
Medical Imaging Informatics Training Program- Administrative Supplement for additional trainee slots. The purpose of this administrative supplement is to request the restoration of several pre- and post-doctoral slots to the UCLA Medical Imagin
MEDICAL IMAGING INFORMATICS TRAINING PROGRAM
The funds will be used to complete the HLA-typing of DNA specimens obtained from children participating in Pediatric AIDS Clinical Trials Group / International Maternal Pediatric Adolescent AIDS Clinical Trials Group protocols which will provid
Supplement-Arkansas Cancer Community Network (AR-CCN) Patient Navigators for the Cancer Care Continuum. The purpose of this application is to expand an existing Patient Navigation Program to address a critical disconnect between incidence and m
Arkansas Cancer Community Network (AR-CCN) Patient Navigators for the Cancer Care Continum
On behalf of the Reproductive Medicine Network (RMN), we, as the Data Coordination Center, submit this request in response to NIH announcement NOT-OD-09-056 for a Recovery Act administrative supplement. We will use the supplement to field a com
The award is for 1. Alteration/Renovation/Repair and 2. Equipment purchase at two clinic sites; one in Avenal and the second in Lemoore, California.  The main objectives include the investment in the infrastructure of the Health Center which wi
ARRA -  Capital Improvement Program: the purpose of CUHCC's CIP Project, Improving the Infrastructure, is to purchase new medical and dental equipment that allows the clinic to better meet the community's need for primary care and dental servic
ARRA Capital Improvement Program.  Two projects exist under the CIP award.  1) Kuakini Site Renovation; and 2) HIT Enhancement.  The Kuakini Site Renovation Project involves West Hawaii Community Health Center's main facility.  The purpose of t
Planned purchase of new digital radiography system to replace conventional film-based X-Ray.
ARRA- Capital Improvement Program: Detroit Community Health Connection, Award#C81CS14160  This project contains three (3) components, which include renovations at two sites and the purchase of equipment for all five of our sites.   The importan
Capital Improvement Program--The CIP funds were used to purchase, train employees, and implement an Electronic Medical Records System and at all location; and to purchase computer equipment to facilitate the implementation of the equipment.
The grant funds are to support work at 6 sites as well as to purchase equipment and IT supplies. 1.  At the Whipple building worn and unsanitary carpet was replaced with vinyl flooring which is easier to keep clean and to maintain. 2.  At Scarb
VISITING NURSE ASSOCIATION OF CENTRAL JERSEY COMMUNITY HEALT
ARRA - Capital Improvement Program.  The award was made available to support capital improvement needs, such as construction, repair, renovation and equipment purchases.  Funds were awarded for two projects.  The first project was to renovate o
Access Community Health Network (ACCESS) received $2.5 million in Capital Improvement Program funding for two projects: the expansion of ACCESS Kedzie Family Health Center and the relocation and construction of ACCESS Cabrini Family Health Cent
ARRA - Capital Improvement Program. These funds were awarded to SCMRC to purchase equipment for its new facility.  It is important to have quality equipment to serve patients.
UNITED NEIGHBORHOOD HEALTH SERVICES, INC.
Grant Name:  Capital Improvement Project for Nashville/Davidson County.  Purpose:  The purpose of this capital improvement grant project is to renovate two clinics in Nashville, Tennessee.  It will enable UNHS to expand the Main Street Clinic a
Primary Health Care, Inc. (PHC) is central Iowa's only community health center.  We have an area population of nearly 600,000.  Consequently, to best serve this large geographic area, we operate from four major decentralized sites plus a freest
Relocation and Renovation of Outreach and Pharmacy; Relocation and Renovation of Marshalltown Dental Clinic
Capital Improvement Program funds were requested to be redirected in March of 2010.  A notice of grant award released the funds in December 2010.  CIP funding is being used to purchase equipment for a new site which opened in February 2010, pur
The Capital Improvement Program (CIP) grant allows funding for projects that feature construction and alteration/repair/renovation; IT/Equipment only; health information technology; and electronic health record projects.  The $ 914,619 award al
ARRA - Capital Improvement Program. Approximately 47,000 residents in Kalamazoo County have unmet needs. FHC has identified four key projects that effectively address the infrastructure necessary to address additional oral, behavioral and prima
UNITED CEREBRAL PALSY ASSOCIATION OF THE NORTH COUNTRY, INC.
ARRA-Capital Improvement Program-The purpose of CIP (Capital Improvement Program) is to create projects that will lead to improvements in access to health services for underserved populations and create health center and construction-related jo
LOWER LIGHTS CHRISTIAN HEALTH CENTER INC
LLCHC will use its $250,000 of CIP money to create a state-of-the-art administrative, billing, and management facility with room for future growth in the location that is eventually planned to be the future permanent site of the health center.
The purpose of the ARRA-Capital Improvement Project for the Kentucky Mountain Health Alliance, Inc. is to construct a newly rennovated facility for our Little Flower Clinic Site. We accessed funds from USDA Rural Development Facilities Loan/Gra
ARRA-Capital Improvement Program-Kentucky Mountain Health Alliance, Inc.
Capital Improvement Program:  These funds will address the needs of the service area, which covers 4251 square miles, by increasing capacity in each site.  Efficiency and effectiveness will increase through modernization and modification of the
The ARRA Capital Improvement Program award will increase the capacity of Alameda County Health Care for the Homeless (ACHCHP) to provide medical services to homeless persons at existing service sites, and enable ACHCHP to expand numbers and hou
BLUE RIDGE COMMUNITY HEALTH SERVICES, INC.
CIP - Capital Improvement Program Blue Ridge Community Health Services proposes to manage patient information by implementing an Electronic Health Record (EHR) as well as a new practice management system which will be linked to the EHR, togethe
ARRA - Capital Improvement Program.  Award funded three projects; HIT Upgrade, Purchase of Medical and Dental Equipment; and Facility Expansion.  All three projects helped support the orgnaizations ability to provide increased access to healthc
The CIP will provide for completion of two projects to enhance the effectiveness, efficiency, quality of care and patient outcomes in two central Illinois community health centers.  The 1st project is an E.H.R. project that will eliminate the m
Component 1, construction of an administrative office, provides the space necessary to allow for component 2 of the project to be accomplished. In order to expand patient services at the Shreveport site these offices would be relocated to a new
ARRA CIP funds were used to purchase telephone and IT equipment for the community health center. The equipment enhanced interdepartment communication, improved our use of our electronic medical system, ultimately affecting over 14,000 patients
The new Utica Community Health Center and particularly the area in which the Utica CHC is located is medically underserved and impoverished. The Utica Project will create a full-service primary care site, including medical, dental and pharmacy
These funds will be used for 3 separate projects (64190-01 Renovation  of Clinica Santa Maria, 64190-02 Dental and Vision Equipment Purchase and 64190-03 EHR Readiness at Clinica Santa Maria). We expect the proposed projects will have several i
A total of $1,418,300 in award funds will be divided between two projects: the renovation of space at Komed Holman Health Center for use as a wellness center, 340b pharmacy, office space and x-ray laboratory ($918,300); and the repair and renov
HOUSING AUTHORITY OF THE CITY OF LOS ANGELES, THE
The Housing Authority of the City of Los Angeles (HACLA) in an effort to create energy efficient green communities, proposes to connect the Rancho San Pedro public housing development to a pedestrian grid with the Public Housing Capital Fund Re
Public Housing Capital Fund Competitive (Recovery Act Funded)
Install continuous automated turbidity, chlorine, and tank level monitoring equipment. Install data logger and satellite radio with transmitter. Install solar panel and battery to power monitoring equipment and radio transmitter. Continuous rea
The Housing Authority of the City of Oxnard has implemented the following project activities using  Capital Fund Recovery Act funding: Project 1:Conducted inspection of lateral drain pipes in Plaza Vista senior building (CA031000005)consisting
1: Stoves & Refrigerators 2: Electrical Upgrades 3:Lanudry drain & Lateral Drain 4: Sliding Glass Doors 5:Vinyl Fencing 6: Units door 7: Trash Compactor 8:Bathrooms Rehab 9: Elevators10: Vinyl Carports
HOUSING AUTHORITY OF THE CITY OF SAN BUENA VENTURA
Conduct modernization activities at various public housing communities.  This funding can be expected to provide employment for architects and engineers, construction workers and product manufacturers.  In addition, this funding can be expected
SACRAMENTO HOUSING & REDEVELOPMENT AGENCY
The County of Sacramento Housing Authority is implementing the following activities using Capital Fund Recovery Act funding: 72 units of the ALTA ARDEN/6045 DRY CREEK/FAIR OAKS/EL P (CA007000202) public housing development are being rehabilitat
County of Sacramento Housing Authority Capital Fund
HOUSING AUTHORITY OF CONTRA COSTA COUNTY
Interior improvements to Public Housing Units.  Project is currently under construction.
Interior improvements to Public Housing Units
HOUSING AUTHORITY OF THE CITY OF LIVERMORE
Public Housing Capital Stimulus and Recovery Grant
1715 (Preventive Maintenance) & 1716 (ADA/Paratransit)
Sustain mass transit service by funding Alameda Contra Costa Transit's (AC Transit) Preventive Maintenance ($29,179,377), and AC Transit/Bay Area Rapid Transit jointly funded Complementary Paratransit Service (East Bay Paratransit): ($3242,152)
Preventive Maintenance and ADA Complementary Paratransit Service
Fiscal Year 2009 Transportation Enhancement projects eligible for funding under the Federal American Recovery and Reinvestment Act (ARRA) for the City of Simi Valley/Simi Valley Transit include funding for the following:  1) TRANSIT SHELTER PRO
Shelters, Buses, Garage Modernization, Wheelchair Scale, Operating Assistance and Non Fixed-Route ADA Paratransit Service
The project is to construct track of the UPRR mainline south of the BNSF crossing. This will give trains the ability to chamber off the mainline track to let other trains pass.
This grant applies the 2009 ARRA Urbanized Area Formula grant allocation of $8,022,665 to bus replacement for a portion of the City of Los Angeles' transit fleet.  The City of Los Angeles Department of Transportation will purchase a total of si
Invest in public transportation by providing assistance to the following projects: COP debt service payment, capital cost of contracting, capitalized preventive maintenance, non-fixed ADA paratransit service operations and transit enhancements.
1.) COP Debt Service, 2.) Capital Cost of Contracting, 3.) Preventive Maintenance, 4.) Non Fixed Route ADA Paratransit Service, 5.) Transit Enhancements
Transit Capital - Bus Replacement of six 1997 diesel buses with six Hybrid Gasoline-Electric buses.
Invest in Public Transportation- Replace five 15+ yeal old diesel buses with new, clean air, gasoline/electirc hybrid buses.  In addition, funds will be used to construct a multi-modal Park and Ride facility featuring: commuter parking, transit
Purchase 4 hybrid buses, 4 gasoline buses; and construct multi-modal Park and Ride Facility
Improve services currently offered at our medical clinic in Niland by replacing aging and failing medical equipment, and purchasing needed office equipment and software to better manage the provision of health care services to our patients. In
Medical Clinic Equipment Purchase Project
Funding will be used to purchase new self contained breathing apparatus (SCBA)at the Fresno County Fire Protection District, Mendota Fire Station in the community of Mendota, Fresno County, California.  The new SCBA will replace worn out and no
Mendota Breathing Apparatus & Driveway Replacement
will be young people in schools, drug traffickers and other suspects who move through our town, Police Officers who benefit by the dog's ability to locate suspects, drugs, and evidence; Search and Rescue teams who need help to locate lost pers
Interpretive exhibit planning and design, design development through final production documents and misc. exhibit needs at Hamilton Grange.
Stablization of Ellis Island Baggage and Dormitory Building, Ellis Island, New York  Hazmat Inspection and Report, Design Development & Construction Document Services.  The building is a 3-story 121,000 square foot structure originally building
Supplemental services and schematic design services for stabilization of seawall at Ellis Island up to 6,450 lineal feet.  Modification includes sea wall core samples and testing not included in original task order
The work consists of preparing pre-design, schematic design, and construction documents for the canopies adjacent to the historic train station at Valley Forge National Historic Park
AE DESIGN SERVICES FOR SCHEMATIC DESIGN DEVELOPMENT AND CONSTRUCTION FOR FURNACE CREEK VISITORS CENTER AT DEATH VALLEY NATIONAL PARK.
Modification 0008, Construct Patchogue Ferry Terminal - Add $82,581 for Option B, Photovoltaic System to include roofing clips.
Jefferson Memorial on the National Mall The work shall be performed during the solicitation, construction, and close-out phases of the construction contract. The work during solicitation phase consists of the review ofbidder Request for Informa
SEDAN: INDEPENDENCE RD RS 97 E 3.5 MILES
Three-day Scoping Meeting & Site Visit to Calumet, Michigan's Union Building, Keweenaw National Historical Park to collect information to prepare a task order proposal for the Phase 2, Interior Rehabilitation.
Death Valley National Park - Title I Preliminary Design Services for Installation of Photovoltaic Systems at Cow Creek Maintenance Comples
Redwood National Park, CA -Title I Preliminary Design Services for Installation of Photovoltaic System at Headquarter/Visitor Center
Manzanar National Historic Site, CA - Title I Preliminary Design Services for Installation of Photovoltaic Systems at Visitor Center Auditorium
JONES & JONES ARCHITECTS AND LANDSCAPE ARCHITECTS, LTD
John Day Fossil Beds National Monument, Oregon -PMIS #146613
Scoping Trip and Preliminary Design Services for Rehabilitation and Expansion of Visitor at Big Hole National Battlefield
LA CLINICA DEL VALLE FAMILY HEALTH CARE CENTER INC
Our CIP grant will provide needed equipment, including IT, and renovations at four health centers managed by La Clinica del Valle Family Health Care Center.  CIP support will allow us to meet the critical health care need in our community by im
CENTRAL OKLAHOMA FAMILY MEDICAL CENTER, INC.
The Capital Improvement Project funds focused on upgrading our practice management/electronic health records systems.  The funds also were used to acquire equipment that was currently on lease through a buy-out plan.
KOKUA KALIHI VALLEY COMPREHENSIVE FAMILY SERVICES
Purpose and scope of award: This CIP project was proposed to alleviate overcrowding at KKV?s main health clinic and to satisfy the ongoing need to maintain secure, reliable and appropriately sized IT equipment for KKV?s growing clinical and adm
CIP, the award will address the needs to the selected VH sites.  The majority of the sites have had significant wear and tear on the facility.  The major construction project, Valley Health Upper Kanawha, will replace a deteriorating 1920?s era
The Capital Improvement Program grant allows funding for projects that feature IT/Equipment enhancements, alteration/repair/renovation projects, and upgrades to the electronic health record.  The $410,335 award will allow the organization to me
STEPHEN F AUSTIN COMMUNITY HEALTH CENTER, INC
For purchase and installation of dental equipment.
ARRA - Capital Improvement Plan.  Crossroads Clinic, a program of Community Action of Laramie County, is working to improve technology at the Clinic.  These funds purchased technology which allows the clinic to better report on medicare claims,
This is an application for a CIP grant to improve the infrastructure associated with three in-scope facilities that compose Houston Community Health Centers, Inc. (HCHC): Airline Children?s Clinic, Denver Harbor Family Medicine Clinic and Denve
NORTHEASTERN OKLAHOMA COMMUNITY HEALTH CENTERS, INC.
Northeastern Oklahoma Community Health Centers (NEOCHC) was awarded grant funds from the Capital Improvement Program (CIP), from Department of Health and Human Services Health Resources Services Administration, June 2009. NEOCHC is a non-profit
ARRA - Capital Improvement Program  The renovation and construction of a new facility has allowed for increased access to healthcare in the Loris community; an area previously lacking in affordable primary care.  The funding has allowed for the
Central Counties Health Centers, Inc. was awarded the Capitol Improvement Program grant.  CCHC is using this funding to purchase equipment necessary to implement an electronic health records (EHR) system at the community health center site in S
This award is the ARRA - Capital Improvement Program. The purpose of this award is to do the following:   1) Fairbanks Facility Energy Efficiency and Dental Operatory Repair and Upgrade. ICHC will perform energy efficient upgrades, install new
SOUTH COVE COMMUNITY HEALTH CENTER, INC.
The renovation of two existing clinics located in the Boston Area.  The first will include the renovation at the medical clinic located at 885 Washington Street which will result in a relocated laboratory and a 57% increase in exam rooms.  The
Capital Improvement Program This award provides for the purchase of replacement and new equipment to provide new and enhanced  services to patients.    Needed supplies for direct patient care and equipment purchased through this project will en
As a result of the Department of Health and Human Services Health Resources and Services Administration Capital Improvement Program (CIP) grant funding through the American Recovery and Reinvestment Act (ARRA), Lamprey Health Care (LHC) will be
A total of 99,942 people live in Franklin County Missouri (U.S. Census Bureau, American Community Survey Estimates, 2008), 10,768 of whom receive Medicaid (Missouri Department of Health and Senior Services). In addition, it is estimated that 15
ARRA - CAPITAL IMPROVEMENT PROGRAM. This funding addresses five of InterCare?s high priority capital expenditure goals including two facility renovations, dental equipment upgrades, a comprehensive technology proposal, and electronic health rec
ARRA-Capital Improvement Project for the renovation/alteration of Bell Gardens Family Medical Health Center, Hawaiian Gardens Health Center, Reggie Rodriguez Park
This proposal includes the following seven projects: Project #1 - Westside Health Center (Alteration, Repair & Renovation): This project includes modifying workflow design in the Health Center; medication dispensing equipment using bar code tec
SOUTHWEST UTAH COMMUNITY HEALTH CENTER, INC.
Grant Name:  ARRA  Capital Improvement Program Purpose:  To renovate a larger space in a facility one block south of the current facility to increase access and be a more efficient use of space. List of Goals: 1.	Improve access to health servic
The purpose of this Capital Improvement Grant award is to expand access to needed primary health care services specifically by creating better efficiencies and productivity through renovations and updating equipment. All funds will be expended
ARRA - CAPITAL IMPROVEMENT PROGRAM (CIP). This funding will be utilized to expand the facility to accommodate three additional exam rooms; expand the waiting rooms for our pediatric and OB/GYN populations; repave the parking lot; add three admi
UNITED METHODIST WESTERN KANSAS MEXICAN- AMERICAN MINISTRIES, INC.
The ARRA Capital Improvement Program award is to address pressing needs in health centers, such as construction, repair, renovation and equipment.  Our agency expanded exam rooms at two of our locations; without these funds we would not have be
ARRA - Capital Improvement Program.  Funding used to purchase computer, dental and medical equipment.
The award provides funding for three distinct capital improvement projects.  The intent is to maintain/enhance the organization's ability to meet the health care needs of the communities we serve, as well to improve clinical and operational eff
The Capital Improvement Program (CIP) will assist our organization in improving efficiency, safety and accessibility of our facility to ensure that we are able to serve more patients in a cost effective and efficient manner. The medical renovat
Replacement of service delivery site-Cottonwood Arizona.  The Capital Improvement Program (CIP) grant funding was used as one-third of the funds required to construct a new Community Health Center of Yavapai (CHCY) facility.  The facility was b
The purpose of this project is the creation of Nestor Community Health Center so that low-income and uninsured residents of Imperial Beach and South San Diego, CA will have increased access to affordable, high quality, primary health care. The
ARRA-Health Center Integrated Services Development Clinic Ole's mission is to be the medical and dental home for Napa County's underserved, providing high-quality, affordable, compassionate and culturally sensitive primary health care.  We are
This award will fund the purchase and implementation of an Electronic Health Record (EHR) for the medical clinics and an Health Information Technology system (Electronic Dental Record) for the dental clinics. The primary goals and objectives fo
North County Health Project, Inc. (NCHS) received funding under the ARRA Capital Improvement Program for 3 projects.  The largest project ($2,018,572) was for the selection and purchase of a certified Electronic Health Records (E H R) software,
The CIP will assist in the Health Care for the Homeless Project's compliance with the Hennepin County Board's direction for the Public Health Department to achieve a shared electronic health record.  This funding will allow us to implement an e
We have twelve projects under this grant; ten of them under Alteration/Repair/Renovation (A/R/R) projects, one IT/Equipment only purchase project and one HIT only purchase project.  The grant funding will allow National Health Services, Inc. (N
COMMUNITY HEALTH CENTERS OF GREATER DAYTON
Capital Improvement Grant awarded under ARRA in the amount of  $250,000 to be allocated as follows: 1. $9,330 for the purpose of expanding the waiting room capacity at Corwin Nixon Health Center to accommodate more patients and provide a more c
The CIP award will address an array of medical issues and the needed capital improvements that accompany those issues. The serviced population comes with a high incidence of tuberculosis and COPD concerns. Specialty clinics staffed by volunteer
COMMUNITY HEALTH CLINICS OF NORTHEAST TEXAS
CHCNET utilized Capital Improvement Program funding to purchase a back-up generator, new phone system, automated patient reminder system, A/C units, AED and dental furnishings and equipment.  CHCNET also utilized funding to purchase a dental EH
The Capital Improvement Program grant allows funding for projects that feature construction and alteration/repair/renovation, IT/Equipment only, health information technology, and overall electronic health record projects. The $460,035 award wi
Overview The CHC submitted a change in scope request, in consultation with the Grants Management Specialist, to eliminate the Certified-EHR purchase, re-allocating funds for this project to the alteration/renovation of the Charnelton Community
Grant Name: Capital Improvement Program (CIP) Purpose: 1. Purchase New Phone System  Project Goals: To update, expand, and improve both internal communications and patient access through purchase, installation, and launch of a new IP telephone
INLAND BEHAVIORAL AND HEALTH SERVICES, INC.
Inland Behavioral and Health Services (IBHS) has carefully considered use of CIP funding so as to have the biggest possible impact on service quantity, quality and efficiency at its three sites in the City of San Bernardino, CA.   Our proposed
The ARRA CIP project is for the purchase of a new, larger and ergonomically improved mobile medical van.  This new van will accommodate the increase in demand for services exemplified by 1840 unduplicated clients and 9932 total visits in the ye
Relocating the existing Eloy clinic into a to be constructed larger building for future growth.  Existing building is leased and has several deficiencies that are not conducive for continued use as a medical clinic.  Eloy is a town with a popul
With the acquisition of a 20 year-old building for our East Tulsa site, there are various repairs, renovations and updates that need to be made to the facility, including the installment of a new roof, resurfacing of the parking lot and signs f
CIP grant funds will provide a)replacement/additional medical, dental and office equipment to better meet the needs of our patient population and enhance our operation efficiencies, b) allow the organization to upgrade its IT infrastructure and
SCRANTON PRIMARY HEALTH CARE CENTER, INC.
Scranton Primary Health Care Center's (Center) Capital Improvement Project (CIP)grant funds three projects; namely, Exterior and Interior Repair Project #1, EHR Project #2 and Equipment Project #3. The $578,300 granted under this CIP award will
ARRA Capital Improvement Program - Loudoun Community Health Center  CIP funds are being used for equipment and improvements to service delivery. We have installed a new telecommunications system to help modernize our telephone and Health IT cap
The Capital Improvement Program (CIP) grants allow funding for projects that feature electronic health records and alteration/repair/renovation.  Arroyo Vista?s CIP projects, Information Technology Improvement Project (ITIP) and Lincoln Heights
Walker Mill Renovation and Expansion: Add 2800 square feet to the Walker Mill Health Center, and renovate existing site.  Project will permit increase in capacity at health center, and facilitate efficiency. Upgrade Equipment at multiple sites:
Capital Improvement Program grant was awarded to expand services at Whitehall Family Health Center by adding new exam rooms, and finish up administrative space in a current shell space. The 2nd project was to include minor refurbishment of the
Whitehall Family Health Center Renovation
COMMUNITY HEALTH CENTERS OF SOUTHERN IOWA, INC.
Project Title:  Leon Facility remodel/repair Project Number: 64174-01 Project Type:  Renovation Grant Number:  C81CS13908 Grantee Name:   Community Health Centers of Southern Iowa Grant Name:  ARRA-Capital Improvement Program  Purpose of Grant:
Because of this, we anticipate that initially the visits for our new patients will focus on addressing existing conditions and providing lots of health education.  When existing conditions are stabilized, these patients will be encouraged to
KONZA PRAIRIE COMMUNITY HEALTH CENTER INC
ARRA - Capital Improvement Program. These funds will allow our clinic to experience patient encounter growth by expanding the facility. The expansion will not result in additional employment for clinic staff, but rather provide work for the con
CENTRAL MISSISSIPPI HEALTH SERVICES, INC.
ARRA - CAPITAL IMPROVEMENT PROGRAM - Central Mississippi Health Services (CMHS), a community health center, provides comprehensive primary care to the poor inner city population of Jackson, a MUA within Hinds County, Mississippi. Over the past
UPPER PENINSULA ASSOCIATION OF RURAL HEALTH SERVICES, INCORPORATED
Grant Number: C81CS13961-01-02		$483,485 Grant Name: ARRA ? Capital Improvement Program  The purpose of this grant is to provide supplemental funding to Federally Qualified Health Center(FQHC) programs to allow for capital improvement projects
ARRA - Capital Improvement.  The purpose of this funding is to improve the Indian Health Board Facility for low income and underinsured individuals in the Minneapolis area.  Specifically, this funding is focused on updating exam and waiting are
COLUMBUS NEIGHBORHOOD HEALTH CENTER, INC.
The CIP Grant will provide needed renovation and construction for our Administrative Office (600) and St. Stephens Health Center (STS). The 600 Project will increase staff efficiency by grouping various departments together i.e. Medical Affairs
ARRA-Capital Improvement Program is a grant which has given us the oportunity to maximize our facility and services to the patients of our community.This is achieved by permiting the construction of administrative offices, which will leave more
Hudson River HealthCare received federal CIP funding to: 1. expand dental services in New Paltz, NY   2.  expand dental services in Monticello, NY   3.  improve organizational efficiency be relocating and consolidating administrative services i
LAB RENOVATION PROJECT Review of the Goals for the Project:  As the center has increased the number of patients it serves, space accommodations have not kept pace with the patient growth.  The center identified reconfiguring currently unused sp
SOUTHEAST ALABAMA RURAL HEALTH ASSOCIATES
SARHA received its NGA for its CIP application on June 25, 2009 yet, due to an error in HRSA?s system, the release of any of SARHA?s CIP funds was delayed until October 30, 2009.  SARHA was issued a new Notice of Grant Award on October 30, 2009
This award will be utilized to purchase computers, software licenses, e-scribing and a IT support. The updated computer equipment will enhance the operations of the centers to effectively manage the electronic medical record and expedite e-scri
PENINSULA INSTITUTE FOR COMMUNITY HEALTH, INC
Grant Name:  ARRA - Capital Improvement Program for the Alteration-Renovation-Repair of Stoneybrook Physicians, 48th Street Physicians, East End facility and the IT/ equipment purchase for multi-sites. The purpose of the project is to perform a
Community Vehicle: to be used for elderly and handicapped transportation.
FRIENDS OF THE ROUND VALLEY PUBLIC LIBRARY
A Rural Development grant in the amount of $100,000 to the Friends of the Round Valley Public Library to purchase new equipment and furnishings for the new library.
Purchase of new digital mammography unit for Digital Imaging Center at Mendocino Coast District Hospital.
The purpose of the USDA award is to fund the purchase of equipment for a Federally Qualified Health Center site.  The health center site is concurrently completing a construction project to expand its women's health program (also funded by ARRA
ARRA - Community Facilities Grant Program
GRANT FUNDS USED TO EXERCISE OPTION TO PURCHASE FIRE APPARATUS AND COMMUNICATONS EQUIPMENT SECTION OF PROJECT
Community Facility Grant for Preschool modular classroom
Replace old water lines, valves & Hydrants, water storage tanks & elecrical systems & and other old water system components.
SISKIYOU COUNTY ROLLING HILLS MUTUAL WATER COMPANY, INC.
steel pipelines and water storage tank.  Install water meters and fire hydrants. Replace three 10,000 gallon storage tanks with one 130,000 gallon steel storage tank.
Water pipeline and tank replacement project.
The multidisciplinary research team assembled for this proposal will apply an integrated chemical, biological, and hydrological approach in field and laboratory studies to investigate the relationships between nutrient loading, endocrine-disrup
Endocrine-Disrupting Compounds in a Rocky Mountain Stream:  Effect of a Major Wastewater Treatment Plant Upgrade
The goal of this project is to examine the breakup and vaporization of liquid droplets in supersonic flow using numerical simulations and to complement an experimental study funded by a companion award (to the University of Washington). The sim
The overall goal of this project is to develop a technical and economically feasible method to obtain and extract high energy storage products from microalgae through environmentally friendly processes. This goal will be achieved by testing the
Microalgal-based Production of Biofuels and High Energy Combustion Materials
College of Engineering/3304 Patrick F. Taylor Hall
Project Summary. The project is aimed at the full demonstration of an intermediate-band solar cell based on the recently discovered multi-band semiconductor alloy AlyGa1-yAs1-xNx. The research to be undertaken targets fundamental questions in p
Implementation of Intermediate-Band Solar Cells using Multi-Band Semiconductors
Structured illumination(SI) is one of a new generation of techniques which have recently been demonstrated to break the diffraction limit in microscopy. The SI approach to super-resolution involves illuminating the object with a spatial frequen
Advanced Biophotonic Structured Illumination Imaging System Design
Title: ARRA Supplemental Funding for Child Care and Development Fund (CCDF); Description: Provide child care financial assistance to low-income working families and fund activities to improve the quality of child care.
ARRA – Child Care and Development Block Grant
Develop, construct, own and operate a thin-film solar photovoltaic manufacturing facility
Intellectual merit: High-level computation is a necessity of much modern research in chemistry. In particular, electronic structure calculations have become a vital tool for inorganic, organic, and biochemical research. UC Irvine Chemistry is a
Establishment of a Cyber-Enhanced Computational Modeling Facility for Teaching and Research in Chemistry
The award is for purchase of a CD Spectrophotometer for use in the Louisiana State University College of Basic Sciences' Protein Facilty.  The new equipment will serve the research needs of multiple laboratories.
Purchase of Equipment for Polypeptide Synthesis, Purfication, and Analysis
Experimental and Theoretical Investigations of Electrostatic Interactions and Ordering in Highly Charged Colloidal Assemblies  We aim to unveil the form of the fundamental electrostatic interactions by direct measurements of electrostatic inter
Experimental and Theoretical Investigations of Electrostatic Interactions and Ordering in Highly Charged Colloidal Assemblies
This project focuses on the development of a novel method for the formation of organocatalysts using the self-assembly of designed precatalyst modules and its application in asymmetric catalysis. While organocatalysts have been shown to rival t
Modularly designed Organocatalysts for Asymmetric Reactions
Title: Low-Valent Chromium - Molecules, Reactivity and Catalysis  This award supports research on synthetic and mechanistic organometallic chemistry of chromium.
Low-valent Chromium - Molecules, Reactivity and Catalysis
This project will continue work on the further development of Ir(I)-catalyzed enantioselective decarboxylative allylic amidation reaction and the corresponding intermolecular allylic amidation reaction, with particular emphasis on their synthet
Decarbonoxylative Allylic Amidation:  Methods and Synthetic Application
The primary objective of this research is to gain fundamental information and new knowledge on the formation and growth mechanisms of complex organics including polycyclic aromatic hydrocarbons (PAHs), oligomers and polymers in the gas phase, i
Polymerization and Growth Mechanisms of Volatile Organics in the Gas Phase, in Clusters and on Supported Nanocatalysts
This project aims to synthesize and evaluate a new series of fluorescent dyes for potential applications in bioimaging, in bioanalyses or in medicine. These new materials offer a number of unique opportunities compared with currently available
Syntheses and Properties of Near-IR BODIPY-based Fluorophores
SGER: Single Nanoparticle Surface Plasmon Resonance Imaging Proposed here is the development and demonstration of single particle surface plasmon resonance spectroscopy probes of local dielectric constant for label free imaging of nanostructure
SGER: SINGLE NANOPARTICLE SURFACE PLASMON RESONANCE IMAGING
MRI:Acquisition of a 500 MHz NMR to Support Teaching and Research with Undergraduates
'MRI: Acquisition of a Quartz Crystal Microbalance and a Dynamic Light Scattering Apparatus for Undergraduate Education'  This grant will support for the acquisition of a Quartz Crystal Microbalance (QCM) and a Dynamic Light Scattering (DLS) Ap
Chandler Blvd/Dobson Road Intersection, and Dobson Road from Chandler Blvd to Frye Road
Funds will support research into boosting the sensitivity and lowering the power consumption of micro-electromechanical systems, or MEMS. The improvements of these tiny sensor devices that are embedded into semiconductor chips will benefit a wi
CAREER:  Nonlinear Mechanically Amplified MEMS for Sensing and Communication
This CAREER proposal will be awarded using funds made available by the American Recovery and Reinvestment Act of 2009 (Public Law 111-5), and meets the requirements established in Section 2 of the White House Memorandum entitled, Ensuring Respo
Career: Fusion of Multi-scale Sensing and Simulations for Bridge Scour Risk Management
CAREER: Fabrication of Surface Modified Hydroxyapatite Nanofibers and their Composites
The global climate crisis, coupled with the rising cost and growing scarcity of oil, mean that cities throughout the world need to more actively embrace greener, more sustainable modes of transport, including public transit, bicycles and walkin
The research objective of this award is to non-intrusively measure cutting forces during milling at sufficient bandwidth to enable closed-loop control. The research approach consists of extending finite difference time domain methods to accurat
Low Cost, High Bandwidth, and Non-Intrusive Machining Force Measurement System
MRI: Acquisition of a High Speed Imaging System for Fundamental and Applied Research/Teaching at Bradley University
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  Abrasivity is an important property of soil which it is often overlooked due to its less than critical impact in many applications, including con
Study of Soil Abrasivity and Development of a Reliable Soil Abrasivity Index
A critical component of earthquake and tsunami loss reduction is the accurate prediction and design of the response of pile-soil systems under dynamic loading. Despite many years of significant advances in theoretical and experimental research,
NEESR Payload: Characterization of Dynamic Soil-Pile Interaction by Random Vibration Methods
The objective of this study is to develop a photopatternable superhydrophobic nanocomposite coating to achieve a moisture-resistant surface using an innovative micro-condensation principle, mimicking nature. The presence of the biomimetic micro
EAGER: Biomimetic Moisture-Resistant Micro-Condensation Surfaces for Civil and Architectural Engineering
This EAGER program seeks to achieve a substantial increase in knowledge of the healthcare services aimed at improved sustainability decision-making.  The initial focus is on patterns of energy consumption.
EAGER:  Energy Use in Health Care Services
CAREER:  A Low-Cost Efficient Wireless Architecture for Rural Network Connectivity
This award provides funding for a new Research Experiences for Undergraduate site focused on human-centered computing at Clemson University. The objective of the REU site is to provide talented undergraduate students genuine research experience
REU Site: Undergraduate Research in Human-Centered Computing
REU-Research Experiences for Undergraduates Site for Artificial Intelligence, Natural Language Processing and Information Retrieval.  Broaden intellectual horizon of participants through exposure to opportunities available.  Utilize a combinati
REU Site for Artificial Intelligence, Natural Language Processing and Information Retrieval
Collaborative Research: CRI-RUI: II-New Attract: Aerial and Terrestrial Testbed for Research in Aerospace, Computing and Mathematics  -  The objective of this project is to inspire students at Tuskegee University and Auburn University in mathem
Collaborative Research: CRI-RUI: II-New Attract: Aerial and Terrestrial Testbed for Research in Aerospace, Computing and Mathematics
The project develops cryptographic protocol reasoning techniques that take into account algebraic properties of cryptosystems. Traditionally, formal methods for cryptographic protocol verification view cryptographic operations as a black box, i
TC:  Medium:  Collaborative Research:  Unification Laboratory:  Increasing the Power of Cryptographic Protocol Analysis Tools
The growing popularity of wireless networks at the periphery of the Internet, combined with the need for ubiquitous access to video on demand (VoD) applications, calls for a new generation of video streaming technology. This research is investi
NeTS: Small: Scalable Wireless Mesh Network Technology at the Edge for Efficient Mobile Video Data Access on Demand
Human-observer based methods for measuring human motion are labor intensive, qualitative, and difficult to standardize across laboratories, clinical settings, and over time. Moreover, many conditions that affect normal human movements must be d
CPS:Medium:Collaborative Research:Monitoring Human Performance with Wearable Accelerometers
After receiving approval in March 2009, the Housing Authority of the City of Pueblo immediately began preparing bid documents to obligate and expend the ARRA funds.  The first contract was awarded in June 2009.  The final contract was completed
HOUSING AUTHORITY OF CITY OF TRINIDAD INC
This award is a Capital Fund Grant used to assure the continuing integrity of existing public housing units thorugh capital improvements, implimentation of energy efficiency measures, and home modifications to meet Uniform Federal   Accessibili
ARRA Capital Improvements Scattered Sites
concrete sidewalk repair, patio enlargement and door installation, signage,parking lot paving
Upgrade landscaping, vinyl siding, doors and A/C in Comm. Rooms
Public Housing; MacGregor and MacGuffie Bldgs.
Modernization activities for the public housing building.  This funding is expected to employ new roofing jobs.
Replacement of windows in public housing units for the elderly and disabled with energy efficient windows.
Invest in public transportation through building a fleet maintenance facility,  purchasing new or replacement vehicles,  providing some operating and or capital assistance to various grantees around Colorado.
ARRA Colorado Department of Transportation-Transit and Rail Division Primary Recipient Record
This project invests the American Recovery and Reinvestment (ARRA) funds to preserve and enhance public transportation service by funding fleet maintenance, fund transit operational services, renovate existing transit facilities, install state
Fixed Route and Paratransit Transit Operational Costs, Capital Construction and Improvements, Securtiy Upgrades, and Service Vehicle Acquisitions.
Former Wayne Miner Housing Project Properties - Kansas City, Missouri.  Phase I and Phase II Brownfields Assessment.
The purpose of the HPRP Regional Grant Trainings is to provide basic program information to grantees to support nationwide program implementation and success. The task order to Lockheed Martin, through the Community Connections Technical Assist
The purpose of the DRGR Information Referral and Technical Assistance Center is to provide technical assistance and information referrals to new grantees to help them understand the critical timeframe and their responsibilities in setting up ac
HOUSING AUTHORITY OF THE CITY OF NORWALK
Senior court-CT2-3,Thermal pane windows-work is completed. Install PV panels that will supply domestic hot water to residents-completed. Door installation has begun.
Energy Resources Conservation & Development
Capital Improvement Program. DMC received a $979,855 award that will allow our organization to achieve the goal of enhancing DMC?s service delivery in the community.  With CIP funding, DMC implemented three distinct projects which include renov
The SIHB is proposing four project types:  Facility Alteration/Repair, IT/Equipment Purchase, HIT purchase & Certified EHR-related purchase.  Need for improvements in each of these areas have been identified through patient surveys and by provi
Capital Improvement Program to renovate and repair areas within the health center that are worn or malfunctioning from long-term use; utilize outdated technology, tools and equipment and require refurbishing to improve patient flow, accessibili
ARRA - Capital Improvement Program The purpose of the grant is to make capital improvements to improve the quality of service we provide.  At the same time the stimulus money is meant to stimulate the local economy and wherever possible we have
This award titled ARRA - Capital Improvement Program was funded with the purpose and goal of making capital improvements within our organization.  This award is for 4 projects: 2 Leasehold improvements; purchase/install electronic medical recor
Canyonlands Community Health Care received funding for 3 projects to address immediate needs in several rural/frontier Arizona communities. The primary project will be enhancement of existing Certified EHR system. Through the purchase of data c
The grant funds will be used to construct an addition to the current building on the same lot and adjacent lot where LCHCS's Fairfax Clinic is located.  The adjacent lot is owned and is the property of LCHCS. It will add 3,789 new square feet,
FAMILY HEALTH SERVICE OF DARKE COUNTY INC
Remodel main campus to add dental and imaging services and install new roof on old building.
Remodel main campus to add dental and imaging services and install new roof.
HRSA BPHC Capital Improvement Project Grant The Capital Improvement Program(CIP) grant allows PrairieStar to renovate several areas in our office to double the dental department space, provide more in-house laboratory testing, expedite the Medi
The ARRA Capital Improvement Program funds were made available to address capital improvement needs in health centers, such as construction, repair, renovation, and equipment purchases, including health information technology systems.  Tri-City
Phase I--Asher Community Health Center main clinic expansion
Phase I--Asher Community Health Center main clinic expansion.  Demolish the SW corner of the building with a sagging foundation.  Replace with an up to date urgent care room, physical therapy facility, an additional treatment room, and two offi
BELOVED COMMUNITY FAMILY WELLNESS CENTER
Funds were used for partial construction of the Beloved community Family Wellness Center second floor.  The construction project is completed as of January 31, 2010.  Funds were use to constuct office space and a health education room to expand
Beloved Community Family Wellness Center Capital Construction Project Phase 2
Title:  IT/Equipment Purchases, Equipment for Dental and Optometry Departments Purpose:  Purchase dental x-ray equipment, computers, optometry equipment, and other medical equipment. Dental Equipment ? Gardner Family Health Network (GFHN) provi
EAST ARKANSAS FAMILY HEALTH CENTER, INC.
The purpose of the ARRA - Capital Improvement Program was to provide efficient and enhanced services, ultimately generating better patient and staff outcomes.  It was EAFHC's intent to purchase an electronic health record/practice management sy
COMMUNITY HEALTH CENTERS OF THE CENTRAL COAST, INC.
Community Health Centers of the Central Coast, Inc. (CHCCC) was awarded $2,394,065 to fund four projects under the ARRA Capital Improvement Program. (1) Alteration/Renovation/Repair of Nipomo Clinic - this clinic is also where the main administ
Renovations will be completed to expand our pharmacy, purchase an EHR, make eqiupment purchases, add a dental operatory and expand one of the clincs waiting rooms to meet the needs of increasing patients.
To utilize the ARRA grant funds (CIP) for the purpose of purchasing and implementing an electronic medical record with a practice management system.  The funds will cover most of the cost of the hardware, software and training needed to   maxim
FAMILY HEALTH CENTER OF SOUTHERN OKLAHOMA
Grant funding has been used by FHCSO to purchase a CCHIT approved electronic record system (EHS) and associated licenses, hardware, and software.  This project has assisted FHCSO maintain its mission to improve access to care for those most in
SAN FRANCISCO MEDICAL CENTER OUTPATIENT IMPROVEMENT PROGRAMS
RURAL ALLIANCE FOR BETTER FAMILY HEALTH, THE
ARRA - Capital Improvement Program:  This award is allowing us to finish remodeling existing clinic space to establish a dental clinic in a service area where there is only one other dental provider who accepts Medicaid thereby expanding access
CAMcare?s ARRA CIP projects expand our capacity to provide primary and preventive health care services to medically underserved populations, and employment opportunities in the communities we serve. Capital improvements include repair, renovati
ARRA - Capital Improvement Program (CIP).  The CIP grant of $519,570 will enable HealthLinc to create a pediatric suite, expand the dental suite, and to implement a electronic health record (EHR) system.  The pediatric suite is necessary to pro
With the awarded Capital Improvement dollars we will purchase equipment for improved physician services. Abaxis, urine analyzers, hemoglobin A1c, and lead testing machines will enhance point of care knowledge allowing providers to more appropri
The overall purpose of CIP is to enhance CMC's health care delivery system within its network of care.  Renovation of its health centers is designed to improve used of existing space, enhancing patient flow and clinic work patterns and to moder
Community Health Service Agency (CHSA) and the Board of Directors have been implementing a facility improvement program over the last three years in which all Agency facilities were upgraded to meet life and safety standards and were designed f
CIP award for electronic health records and renovation project.
ARRA - Capital Improvement Program.  Construction of a new medical & dental clinic to serve patients in the Rifle Colorado area.  Goals of this were to add staff of 18; see 4500 more patients in 11250 visits, dental and Medical.  THis is very i
ARRA Capital Improvement Program (CIP). This funding is allowing us to purchase equipment to upgrade our Electronic Medical Record, telecommunication system and dental laboratory. These upgrades   will allow current systems to run more efficien
Clinical and non-clinical equipment to improve quality of existing services.  This project is replacing outdated clinical equipment and allowing the purchase of additional equipment for patient care (vital signs monitors, diabetic analysis, aud
Dayspring strives to provide high quality care to our patients and to meet or exceed our patient expectations.  Our current hard copy medical record has increasingly become an obstacle to providing such care. AS a multi-site Community Health Ce
Hana Health Nutrition Center -Construction. Development of a Nutrition Center to allow for expansion of nutrition based health and wellness programs in the geographically remote district of Hana,Maui.
Hana Health Nutrition Center - construction
The CIP grant allows funding for projects that feature construction and alteration/repair /renovation. The $385,835 will allow the organization to meet goals of improved access by enlarging and expanding the physical space of the clinic by addi
Capital Improvement Project  Project One ? Certified EHR -HMS will replace 30 computers in its health centers that are over 5 years old and prone to repairs.   -The CIP will be used to pay for employee training and two years of on-going costs o
COMMUNITY HEALTH CENTER OF CENTRAL WYOMING, INC.
Our CIP funding will be primarily directed toward HIT and infrastructure support, but it will also expand healthcare access for 240 new patients and generate 1400 additional visits. The CHCCW will utilize CIP funding to make vast organizational
NORTHWEST BUFFALO COMMUNITY HEALTH CARE CENTER
The Capital Improvement Project is providing funds needed to prepare NWBCHCC for Electronic Health Records.  This includes purchasing licenses for Allscripts Practice Management and Eleectronic Health Records.  In addition, the funds are being
The Rosa Parks site contains, with 198 dwelling units for seniors/persons with disabilities, and a separate senior center community facilities building. The $2,780,755 in CFRC grant funds will be used for three activity types and address the ne
ARRA Capital Fund Program Competitive Grant
This project will remove clay sewer line and replace with DUC pipe.
HOUSING AUTHORITY OF THE COUNTY OF RIVERSIDE
ARRA Capital Fund Recovery Grant (Formula)
AREA HOUSING AUTHORITY OF THE COUNTY OF VENTURA
Window replacement at 5 Public Housing Sites. These new dual glazed windows, will increase energy efficiency of the units by using less gas and electricity to heat and cool.
MOUNTAINVIEW VILLAGE OF HUMBLE COUNTY INC
HOUSING AUTHORITY OF THE COUNTY OF TULARE
Modernization of family units with energy efficient windows, replacement of patio doorsm roofs, repairs of carports.
Capital Fund Recovery Act formula grant for Public Housing
Pulbic Housing Capital Fund Stimulus (Formula) Recovery Act Funded
Conduct modernization activities at Kottinger Place, a 50-unit Public Housing development located in Pleasanton, California.  This funding can be expected to result in providing direct and indirect employment for architects, engineers, construc
The Housing Authority of County of Marin is implementing the following activities using Capital Fund Recovery Act funding:  The  Kruger Pines (CA052000002) public housing development units are being rehabilitated to increase UFAS accessibility
Capital Fund Competitive (Recovery Act Funded) UFAS Grant
nvest in public transportation. These funds will partially finance the purchase of one replacement hybri bus. The bus to be replaced is a 1998 40', low floor diesel fixed route bus. This bus will have met the end of its useful life by 2010. The
5311 Transit Improvements in non-urban areas
The overall purpose of the grant is to invest in public transportation to improve the safety and reliablity of the transit system and to improve the passenger comfort in the modified revenue vehicles.  Therefore, the BART passengers should have
Replacement of Train Auxiliary Power Equipment, Cables on Transbay Tube, and Coverboards, Improve walkway safey at a station, Car Interior Modifications, and Wheel Truing Machine Study.
Invest in public transportation by imrpovement of bus stop including, but not limited to, installation of bus shelters, benches, and trash recepticles at over 50 locations. The City of Tracy currently operates 5 fixed bus routes serving over 90
Invest in public transportation by rehabilitating light rail vehicles; engaging in preventive maintenance activities to preserve/extend the functionality of the SFMTA's assets; rehabilitating articulated motor coaches; upgrading the SFMTA’s m
Infrastructure Enhancement and Maintenance Projects
Invest in public transportation Projects 1. Fund preventative Maintenance on transit vehicles 2. Repower MCI Coaches by replacing diesel particulate filters to comply with Ca Air Resources Board regulations and prolong the life of the vehicle 3
Invest in public transportation by providing funds for transit operating, preventive maintenance of buses, ADA paratransit service operations, and transit enhancements including solar bus shelters, benches and map display cases from Tolar Manuf
Transit Operations, ADA Paratransit Operations, Preventative Maintenance, Transit Enhancements
Monterey-Salinas Transit Capitalized Preventive Maintenance;Lease (46) 40-Ft Buses, Acquire Mobile Fare Coll Equip.
Lease (46) 40-Ft Buses, Fare Equip. PM & OP
SAN JOAQUIN REGIONAL TRANSIT DISTRICT RTD
This grant, CA-96-X045, will provide funds for preventive maintenance for upkeep of San Joaquin Regional Transit District's buses and paratransit vehicles.  Funds will also be used for the following projects: Construction of the Mall Transfer S
Public Housing Capital Fund Stimulus Funds
HOUSING AUTHORITY OF THE CITY OF ANSONIA
Award to be used decentralize utilities for 4 tenant-occupied buildings.
Conduct mdernization activities- more specifically the renovations or near-gut rehab of kitchens and bathrooms in vacant low income public housig units.
Public Housing Capital Fund Stimulus (formula) Recovery Act Funded
Conduct modernization activities in public housing unit
Replacement of out-dated baseboard heaters with Energy Efficient baseboard heaters and Energy Efficient thermostats.
545 - Combination Loan & Grant - Waste Disposal Only - 09/10 Stimulus       The facility was constructed in 1972 and many components of the treatment process have exceeded their useful life expectancy.  In 2003, the Connecticut Dep directed the
Estimated project cost is $55,211.  This 0.8 mile project consists of rehabilitation of the paved surface and safety improvements along the entire road corridor. The safety improvement portion of the project is phase I and will include removal
Estimated Project cost is $74,586.  The project is 0.9 miles long and consists of rehabilitation of the paved surface and safety improvements along the enire road corridor.  The safety improvement portino of the project is phase I and will incl
ARRA/IRR Lodge Grass Housing, YC00370014
This project is 2.4 miles long. There is a considerable amount of crack sealing to be completed on this project and well as substantial repair to the aged right-of-way fencing. The safety improvement portion of the project will include removal
This 3.3 mile long project consists of rehabilitation of the paved surface and safety improvements within the road corridor. The safety improvement portion of the project is phase I and will include removal of any obstructions in the right-of-w
This project is 3.0 miles long. The safety improvement portion of the project will include removal of any obstructions in the right-of-way, repair curb, gutter and sidewalk, clean and repair drainage structures, and update/install road signs an
This project is 1.5 miles in length and consists of rehabilitation of the paved surface. Work will include removal of any obstructions in the right-of-way, repair right-of-way fence, clean and repair drainage structures, and update/install road
Estimated project cost is $117,137.  This project is 1.5 miles in length and consists of rehabilitation of the paved surface. Work will include removal of any obstructions in the right-of-way, repair right-of-way fence, clean and repair drainag
This Project is located on Route 2 and is 9.7 miles in length. The project consists of a rehabilitation of the paved surface and safety improvements along the entire road corridor. The safety improvement of the project is phase I and will inclu
ARRA- IRR Project Sangrey School and Laredo
Identify and remediate priority health hazards in high risk target housing where environmental conditions may contribute to a child's illness or risk of injury; support public education and outreach that furthers the goal of protecting children
South Kitsap Industrial Area Connector Phase 1
ARRA- Health Careers Opportunity Program.  YVFWC ConneX: Connecting Students to Health Careers  The goals of the Yakima Valley ConneX program are to improve access to healthcare in underserved areas and decrease health disparities among vulnera
ARRA - Health Careers Opportunity Program
The goal of the Health Careers Opportunity Program (HCOP) is to assist individuals from disadvantaged backgrounds to undertake education to enter a health profession. The HCOP program works to build diversity in the health fields by providing s
'The goal of the Centers of Excellence (COE) is to assist eligible schools in supporting programs of excellence in health professions education for underrepresented minority individuals. To qualify as a minority Center of Excellence, a health p
Manufacture, deliver and install precast concrete restroom facilities.
Manufacture, deliver and install precast concrete restroom at the Point Reyes National Seashore.
RESEARCH FOUNDATION FOR MENTAL HYGIENE INC
This application will use PET radioligand imaging, which is the only modality currently available to investigate the neurochemistry of cocaine addiction in the human brain in vivo. The advantage of this methodology is that it allows the more di
PET Imaging of the mGluR5 in Cocaine Abuse
Steam and condensate repair in building mechanical rooms.
Implement the Science and Engineering support, mobilization and demobilizations, construction site temporary facilities, excavates, separate and process ready for shipment radiological contaminated soils and debris, transportation for disposal
U.S. Army Corps of Engineers, except civil program financing
As a part of Military Program Operation & Maintenance, Air Force, Recovery Act, Spill Prevention Control/Countermeasures for Above Ground Storage Tank Inspections for various Air Force Installations in support of AFCEE.   The Contractor shall p
ANDERSON CONSTRUCTION COMPANY OF FORT GAINES
ARRA Notice 55 - The purpose of this modification is to add critical repair upgrades to campsites at Bluff Creek, Cotton Hill, Hardridge, and White Oak, construct replacement gate attendant stations, renovate Fish Cleaning Station at Cotton Hil
Receive and Dispose of 11(e) 2 Materials generated prior to November 8, 1978, in the stated quantities, for Maywood Formerly Utilized Sites Remedial Action Program (FUSRAP) Site, Maywood, New Jersey. A generator is required to schedule delivery
Recovery Project # 116941, Kentucky Lock & Dam, Tennessee River, KY. Engineering during construction services for the Paducah and Louisville railroad relocation at Kentucky Lock and Dam of the Nashville District U.S. Army Corps of Engineers.
Intellectual merit. Coherent anti-Stokes Raman scattering (CARS) microscopy is maturing as the method of choice for rapid chemically selective imaging of label-free biological cells and micro-structured materials. At present, the resolution of
CAREER:  Super-Resolution in Coherent Anti-Stokes Raman Scattering (CARS) Microscopy
The University of Akron REU Site provides a research program for undergraduates during the summers of 2009-2011.  Six students were selected for this first of three years to participate in an intensive 10-week research program in 'Ecology at th
REU: Site:  Ecology at the Urban-Rural Interface
In this project, we propose several advancements of the GEOLocate toolkit, including 1) enhancing its web services for natural language processing and georeferencing of locality descriptions; 2) improving GEOLocate’s core algorithm for more e
Improving GEOLocate to Better Serve Biodiveristy Informatics
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  Much of biology is regulated by the specific and high-affinity binding of ligands to proteins and nucleic acids. In most cases, however, the inte
MRI: Acquisition of High-Throughput Calorimeters for Ligand-Biopolymer Discovery and Characterization
MRI: Acquisition of a Scanning Electron Microscope for a Multi-User Core Facility in Science, Engineering, and Technology
The immediate goal of this project is to increase the number of students from under-represented groups who enter graduate programs in biological research upon graduation from Wilkes University. The ultimate goal is to increase the number of PhD
URM: Mentoring Minority Students to Graduate Success through Year-Round Research Projects
CFRC funds will be used for modifications to dwelling units to make them fully accessible in accordance with UFAS,improvements to non-dwelling areas to make them accessible and ADA-compliant, and improvements to and construction of non-dwelling
Lead Hazard Reduction Demonstration Grant
Award funds used for demolition of Riverside Apartments, the renovation and occupancy of 59 vacancy reduction units in Northeast, renovation of vacancy reduction units at Southbridge, vacant unit reduction at Scattered Sites, and bathroom renov
142727 - Concentrating Solar Power - National Solar Tower Testing Facility (NSTTF) Upgrade (Capital Equipment Project);  Funds are provided for the Concentrating Solar Power Program and are used to upgrade the Molten Salt Facility instruments,v
Advanced Research Projects Agency-Energy (ARPA-E):  ORNL has received funding for two subprojects from ARPA-E.  The first award occurred in September 2009 for ARPA-E Reviews.  This award provided funding of $20,000 for ORNL employees to review
Title:  58100  Merit Review  Purpose:  Provide Merit Reviewers for DOE Biomass Solicitation  Description:  To provide technical experts to assist in reviewing biomass proposals submitted to DOE  Milestones:  Complete reviews, November 30, 2009
Award Title:  Enhance and Accelerate FEMP Service Functions t the Federal Government Purpose:   PNNL will provide technical assistance to enhance and accelerate Federal Energy Management Program (FEMP) service functions to the Federal governmen
1. Award Description field should include the following elements;  a. Award Title  Environmental Molecular Sciences Laboratory   b. Award Purpose  The Recovery Act funding will accelerate the planned capital equipment improvements to the Enviro
There are two scopes of work for this project.  1)  Idaho National Laboratory (INL) will provide direct Technical Assistance to the Energy Efficiency Conservation Block Grant (EECBG) Recovery Act recipients including assisting with developing a
WASHINGTON RIVER PROTECTION SOLUTIONS LLC
The American Recovery and Reinvestment Act (ARRA) provided funding to accelerate Tank Operations Contract (TOC) out year work scope into Fiscal Years 2009 thru 2011. The benefits of acceleration were increased reliability and availability of in
The goal of this procurement is to provide technical and drilling services for the ARRA project at Los Alamos Site Office. The Contractor shall provide expert drilling subject matter expert (SME) support to provide technical oversight assistanc
National Environmental Policy Act Support Services.
Support of all Task Order pre-award support under the DOE IDIQ.
The Hawaiian Islands provide an unparalleled system for understanding species formation. This biodiversity hotspot contains large numbers of species that occur nowhere else in the world. One very diverse group is the Hawaiian files (Diptera). D
A Comparative Approach to Dating the Diversification of Hawaiian Diptera
One Shields Ave, University of California
Grant to study climate change effects on sand dune restoration using lab and field experiments and field surveys, with scientific papers and management recommendations being the main outputs and outcomes.
Collaborative research: can microbial symbionts mediate effects of climate change on the functioning of an ecosystem engineer?
Genome evolution in natural populations and synthetic lines of allopolyploids in Tragopogon (Asteraceae)  Most of what we know about the genetic and genomic consequences of polyploidy (genome doubling) is derived from the study of crops, synthe
Collaborative Research: Genome evolution in natural populations and synthetic lines of allopolyploids in Tragopogon (Asteraceae)
The major goal of this research is to understand the molecular genetic basis of adaptation to seasonality in the model organism Drosophila melanogaster. Although this species is endemic to sub-Saharan Africa, a form of reproductive diapause (an
ARRA: COLLABORATIVE RESEARCH: Evolutionary Dynamics  of a Molecular Polymorphism for Diapause and Life Histories in Drosophila Melanogaster
Assembling the Viral Tree of Life research project will focus on understanding the evolutionary relationships between viruses and cellular life; helping to bridge the gap in our knowledge of archaeal viruses and their evolutionary relationships
SOUTHERN CALIFORNIA REGIONAL RAIL AUTHORITY
Invest in public transportation for 1) Improve Keller Rail Yard; 2) Partial funding for Positive Train Control (PTC) system on the Southern California Regional Rail Authority's (SCRRA) Metrolink commuter train system Los Angeles, Orange, Rivers
Invest in transportation, environmental protection, and other infrastructure that will provide long-term economic benefits.  Expansion of the commuter fleet with the purchase of three 45 foot, 57 passenger, clean diesel buses
Perchase 1 replacement coach for Clean Air Express,2 ADA vans, 4 replacement buses for local service, 6 particulate traps for existing buses, bus security cameras, and 6 bike racks.  The Clean Air Express Coach and the 4 replacement buses have
Capital equipment and security improvements
investment in public transportation through the design engineering and construction of a transit transfer terminal in the downtown area of the City of El Centro
Invest in public transportation by purchasing new replacement paratransit vehicles.
Purchase of 2 replacement paratransit vehicles.
Invest in public transportation by purchasing replacement transit vehicles and implementing bus stop improvements. The funds will be utilized to 1) purchase up to three 18 passenger, up to 30-foot, CNG-powered cut-away buses that have an expect
30' and 35' Bus Replacement and Bus Stop Improvements
Funding is for improvement of current medical services and addition of transportation services at the Winterhaven clinic. Purchases include  replacement of facility water heater,  software licenses and a transportation vehicle. The new water h
Awarded grant will assist in purchasing a new police vehicle and related emergency equipment required, acquire a new K-9 dog and necessary equipment/materials, assist in covering personnel training.  The K-9 will be certified breed and will be
City of Firebaugh K-9 dog and police vehicle
Purchase of Miscellaneous Police Department Items and Equipment
SURPRISE VALLEY JOINT UNIFIED SCHOOL DISTRICT
USDA grant funds to be used to supplement the district's funds to move and rehabilitate three modular classrooms to become a childcare facility.
Seating in Multipurpose Building Project
DRIVE IN REFRIGERATOR FOR COMMUNITY FOOD BANK
Replace an existing building with a new modular building for the family ed. center.
City of Long Beach Healthy Homes Demonstration Program
544-(Combo Loan and Grant) Water Only - 09/10 Stimulus
Water Pipeline and tank replacement project
Watewater Treatment Plant Upgrade and Expansion
Helical mesoporous silica is attractive because of its potential applications in chiral catalysis and separations, which are of great interest in the pharmaceutical industry. The objective of this proposed research is to fabricate helical mesop
Fabrication of Helical Mesoporous Silica Tubes with Confined Assembly Process
This project is to obtain a state-of-the-art high resolution inductively coupled plasma mass spectrometer (HR-ICP-MS), which will be located at the University of Mississippi (UM), Department of Chemistry and Biochemistry. The instrument utilize
MRI: Acquisition of a High Resolution Inductively Coupled Plasma Mass Spectrometer for the Mid-South Region
In this project a system will be developed, built and tested, that can perform multiscale, time resolved, 3D velocity measurements within a finite sample volume of a fluid flow. This instrument integrates and extends the capability of two state
MRI: Development of Combined Holographic and Tomographic PIV Systems for Time Resolved, Multiscale, 3D Velocity Measurements Within Turbulent Shear Flows
In initial work the PIs have achieved efficient solar conversion of carbon dioxide and water vapor to methane and other hydrocarbons using nitrogen doped titania nanotube arrays, with a wall thickness low enough to facilitate effective carrier
EFFICIENT PHOTOCATALYTIC CONVERSIONS OF CO2 AND WATER VAPOR TO HYDROCARBON FUELS USING SUNLIGHT
Although the formation of amorphous oxide thin films by low-temperature oxidation of metals is of significant importance for many technological applications including heterogeneous catalysis, electronics, corrosion protection, and surface coati
ARRA: Making Superior Alumina Thin Films Via Ozone Oxidation of Aluminum: Correlation Between Oxidation Mechanism and Nanoscale Atomic Sstructure in Amorphous Oxide Films
The overall goal of the proposed research is to functionalize Si nanoparticles to target common cancers, enhance the NMR signal of these particles using dynamic nuclear polarization (DNP), and characterize the hyperpolarized particles in vitro.
Understanding Dendrite Abatement in Reaction-Engineered Battery
Many emerging and future electronics applications require large amounts of digital signal processing, and operate with very limited power budgets. Examples include: many types of wireless communications, medical imaging such as ultrasound, sens
Architectures for Highly-Efficient 1000+ Core Chips for Compute and Data-Intensive Applications
Summary: Formal Analysis of Complex Systems A Collaborative Proposal Involving CMU, CUNY, NYU, Stony Brook, UMD, Cornell, JPL This Expedition, under the directorship of Lead PI Edmund M. Clarke, will develop new computational tools to help scie
ARRA: Collaborative Research: Next-Generation Model Checking and Abstract Interpretation with a Focus on Embedded Control and Systems Biology
Intersection of Tom Darlington Drive and Ridgeview Place
ARRA Energy improvements at Broad Park Manor
Support the NBL's plutonium fire upgrad project for the duration of the project
The Analytical and Surface Chemistry (ASC) Program of the Division of Chemistry and the Solid State and Material chemistry (SSMC) Program of the Division of Material Research (DMR) supports the highly synergistic collaborative research project
Two-Dimensional Systems of Molecular Rotors
The goal of the proposed research is to dramatically enhance the technical capabilities available in the Wayne State University Department of Chemistry through the acquisition of a new, 600 MHz NMR spectrometer.  The instrument including a micr
ACQUISITION OF A CYBER-ENABLED 600 MHz NMR SPECTROMETER FOR RESEARCH AND TEACHING
Purchase of an X-Ray Diffractometer' Purpose:  Purchase of X-ray diffractometer molecular structure determination by collection of X-ray diffraction data from single crystals.
The research projects proposed are initiated by a recent discovery from PI's research group: novel synthesis of 4,5-disubstituted-NH-triazoles and their application in Rh(I) and Au(I) catalyzed reactions.  The focus of this proposal is to inves
CAREER: Developing 1,2,3-triazole skeletons as novel chiral building blocks in asymmetric catalysis
Research Overview  The proposed work is focused on the development and application of a new chemical modification- and mass spectrometry-based technique, termed SPROX (Stability of Proteins from Rates of OXidation), that can be used to measure
A Chemical Modification- and Mass Spectrometry-Based Method for Thermodynamic Analysis of Protein-Ligand Binding
that will aid chemists in the design of polymers with sophisticated sequence control.
Metal Redox Control of Polymer Properties
John Tully of Yale University is supported by an award from the Theoretical and Computational Chemistry program within the Division of Chemistry to engage in research to advance our atomic-level understanding of dynamical processes in large mol
Chemical Dynamics in Condensed Phases and at Surfaces
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).   This project will continue work on the development and optimization of different chemoselective oxidation procedures using water-soluble hyperva
RUI: Selective Oxidative Transformations Using Water-Soluble Hypervalent Iodine Reagents
This award will support year-round research in asymmetric catalysis with undergraduate students in the Chemistry Department at Vassar College.  The research focuses on applying multiple asymmetric induction phenomena with the objective of enhan
RUI:  Enhancing Enantioselectivity in Lewis Acid Catalysis through multiple asymmetric induction
Professor Martin Jarrold and his students will study melting and freezing transitions in isolated metal nanoclusters with 10-1000 atoms. Phase transitions like melting and freezing are normally associated with bulk objects. This work will exami
Phase Transitions and the Properties of Liquid Nanoclusters
Through this award from the Major Research Instrumentation (MRI) program, Professor Fadi Bou-Abdallah at SUNY Potsdam will acquire an isothermal titration calorimeter. It will support the research of colleagues at Potsdam, and nearby St Lawrenc
ARRA: MRI: Acquisition of an Isothermal Titration Calorimeter
Grant award supports the acquisition of an Olis DSM 20 circular dichroism (CD) spectrophotometer for the Departments of Chemistry and Biological Sciences at Wellesley College. The acquisition of a CD spectrophotometer will allow Wellesley facul
Acquisition of Mass Spectrometry Instrumentation for Chemistry and Biology research - With this award from the Major Research Instrumentation (MRI) program, the Chemistry Department at Grinnell College will acquire an ion trap gas chromatograph
MRI: Acquisition of Mass Spectrometry Instrumentation for Chemistry and Biology research
Price Road from Germann Road south to Queen Creek Road
The Alabama Department of Public Health (ADPH) Healthcare-Associated Infections (HAI) Reporting and Prevention program will coordinate and develop the State HAI plan, submit the plan by January 1, 2009, and implement prevention activities towar
Epidemiology and Laboratory Capacity for Infectious Diseases (ELC) Healthcare-Associated Infections - Building and Sustaining State Programs to Prevent Healthcare -Associated Infections
The research objective of this Faculty Early Career Development (CAREER) project is to study the systematic analysis and design of distributed controllers that guarantee constraint satisfaction in large scale networked dynamical systems. The pr
CAREER: Distributed Control and Constraints Satisfaction in Complex Networked Systems
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  The research objective of this award is to advance the manufacture, the fundamental understanding, and the device application of graphene-nanocry
Collaborative Research: Exploration of Graphene-Nanocrystal Metamaterials
Recent earthquakes have provided numerous examples of the devastating effects of earthquake surface fault rupture on structures. Several major cities are built in areas containing active faults that can break the ground surface (e.g., Los A
Earthquake Surface Fault Rupture Interaction with Building Foundations
The objective of this work is to develop accurate and efficient  computational methods for the simulation of resonant damping in  micro-electromechanical devices such as are planned for next generation  sensing-arrays and communication circuitr
High Performance Simulation Tools for Complex MEMS Resonator Design
This award is an outcome of the NSF 09-524 program solicitation ''George E. Brown, Jr. Network for Earthquake Engineering Simulation (NEES) Research (NEESR). This project will utilize the NEES equipment site at the University of California at D
NEESR-CR: Seismic Earth Pressures on Retaining Structures
Hundreds of billions of dollars and thousands of lives are at risk when a major earthquake shakes a metropolitan area. Building damage or collapse is one of the primary contributors to the risk. Huge investments are being made to improve perfor
NEESR-CR:  Design of Soil and Structure Compatible Yielding to Improve System Performance
Engineering versatile drug delivery vehicles that enable simultaneous delivery of several agents is a key challenge in medicine. Liposomes would gain significant stability and functional capacity from having a solid core, tethered to the bilaye
CDI Type II:  Cyber-Engineering Functional Nanoparticles for Targeted Drug Delivery
This is a renewal of the previously funded REU Site NSF Award No. 0552758. This 10 week REU Site program in MAS-net (Mobile Actuator Sensor Networks) provides eight undergraduate students an opportunity to participate in the ongoing research ac
REU SITE: MOBILE ACTUATOR AND SENSOR NETWORKS (MAS-NET)
Given the U.S. demographic trends (aging population, increasing prevalence of chronic diseases), nursing staff shortages, and decreasing hospital capacities, it is no surprise that the U.S. healthcare system faces immense challenges on a daily
II-NEW: miSense: Platform for Medical Sensing Applications
CSR: Large: Collaborative Research: Multicore Application Modeling Infrastructure (MAMI)
It is commonly understood that to achieve a desired level of security in wireless networks is a bigger challenge than in wired networks. The denial of service (DoS) attack is a prominent threat in wired networks, and is a more potent threat in
NeTS: Small: xBeam: Cross-Layer Beamforming Against Denial of Service Attacks in Wireless Networks
Modern automobiles and flight avionics systems form complex distributed real-time and embedded (DRE) systems. A key challenge for these DRE system developers, however, is that the techniques for determining the best way of deploying software co
SHF: Small:  Automating the Deployment of Distributed Real-Time and Embedded System Software Using Hybrid Heuristics-Based Search Techniques
This research will develop a Holistic Transparent Performance Assurance(HTPA) framework to support performance sensitive wireless applications, which will provide merit to Fine-grained Spectrum Profiling, Medium Access Control Virtualization, a
NeTS:  Small:  Collaborative Research:  Holistic Transparent Performance Assurance Within The Crowded Spectrum.
HOUSING AUTHORITY OF THE CITY AND COUNTY OF DENVER
The new construction of a senior/disabled high-rise building will include 100 replacement public housing units and community facilities as part of a mixed-finance project.  The proposed 100 unit senior/disabled building will be designed to meet
10th & Osage Senior/Disabled Housing and Community Center
Rehabilitation of 42 Public Housing Units for Energy Efficiency, including energy efficient lighting, high efficiency furnaces and boilers,irrigation controllers with rain sensors to conserve water and insulation.
Rehabilitation of 154 Public Housing Units with Energy Upgrades including high efficiency furnaces, air conditioners and efficient lighting. Insulation was added to some units as well.
replace windows to entry doors, replace appliances, insualtion, thresholds, door sweeps, outlets
Project includes installing a water efficient sprinkler system, new white vinyl privacy fences, and new energy efficient hinged patio doors
Public Housing Capital Fund Stimulus Recovery Act Funded
United States Soldiers' and Airmen's Home
Public Housing Capital Fund Recovery Grant.
Invest in public transportation by purchasing Automated Passenger Counter (APC) for Light Rail Vehicles, the 16th Street Mall Shuttles, and buses that operate on the I-25 HOV lanes.  The APC's register detailed data on passenger boarding and al
ARRA Purchase Automated Passenger Counter
The ARRA contract action funded under M0039 to the HITS contract #C-OPC-22807 covers the HITS Work Request #WR-0900327 requirements to provide infrastructure upgrade services to support the Recovery Act Management and Performance System (RAMPS)
Environmental Management Program Support - Provide environmental regulatory compliance support including review of regulatory documents, support for Environmental Management Division oversight activities, assessment of environmental compliance
Provide assistance processing all types of contract modifications. Ensure the timely and accurate compliance with ARRA reporting requirements. Coordinating with DOE-RL Integrated Project Teams (IPT) to ensure timely and compliant resolution of
The Maryland Energy Administration (MEA) has developed a four-pronged approach to promote affordable, reliable and clean energy using monies from the federal American Recovery and Reinvestment Act and Maryland's state Strategic Energy Investmen
ARRA Supplemental Funding for Weatherization Assistance to Low-Income Persons: To reduce energy costs for low-income families, particularily for the elderly, people with disabilities, and children, by improving the energy efficiency of their ho
ARRA Department of Energy Weatherization Assistance Program
2009 ARRA Weatherization Assistance Program
ARRA Supplemental Funding for Weatherization Assistance to Low-Income Persons: To reduce energy costs for low-income families, particularly for the elderly, people with disabilities, and children, by improving the energy efficiency of their hom
Weatherization Assistance for Low-Income Persons
The Montana State Energy Program (SEP) ARRA plan will create and retain Montana jobs, save significant amounts of energy and taxpayer dollars in public and residential buildings, and lead to an increase in renewable energy production. SEP ARRA
ARRA - Supplemental Funding for Weatherization Assistance to Low-Income Persons:  To reduce energy costs for low-income families, particularly for the elderlly, people with disabilities and children, by improving the energy efficiency of their
Recovery Act - Weatherization Assistance Program for Low Icome Persons
• Facility Retrofit:  A grant program to promote a pre-selected set of energy efficiency upgrades for public, Tribal entities, non profit and joint powers boards owned facilities.  Specifically, the grants would only be used to improve seven
Recovery Act - State Energy Program for the State of Wyoming
FUNDING TO BE USED TO INCREASE THE ENERGY EFFICIENCY OF DWELLINGS OWNED OR OCCUPIED BY LOW-INCOME PERSONS, REDUCE THEIR TOTAL RESIDENTIAL EXPENDITURES AND IMPROVE THEIR HEALTH AND SAFETY.
WEATHERIZATION ASSISTANCE FOR LOW-INCOME PERSONS
Recovery Act - The State Energy Program -- This award will be used for activities related to increasing energy efficiency and reductions in energy costs and consumption for consumers, businesses, government, and schools; reductions in the relia
Recovery Act:  Commonwealth of Kentucky State Energy Program
The purpose of this grant is to support the implement the American Recovery and Reinvestment Act of 2009 in Arkansas.  The goal is to preserve and create jobs and promote economic recovery; to assist those most impacted by the recession; to pro
The proposed project was to improve the energy efficiency of the City of Spartanburg's owned buildings. The grant funds will be utilized to replace occupancy sensors, windows, doors, heating and air conditioning. The program will result in sust
Energy Efficiency and Conservation Block Grant.
Sysco Houston, Inc. will deploy 72 class 3 fuel cell forklifts and 26 class 2 fuel cell forklifts at its new 585,000 ft2 distribution center in Houston, Texas.   Also, hydrogen fueling infrastructure will be installed to provide the fuel for th
Fuel Cell-Powered Lift Truck Fleet Deployment
Other Grocery and Related Products Merchant Wholesalers
The Project will develop a new and revolutionary materials coating technology which allows a PV module maker to apply an antireflection coating to the cover glass of their modules in their own facility, and thus gain at least a 3% increase in t
A Low Cost Solar PV Anti-reflection Coating
In this program, we will enhance the Aerosol Jet technology to enable the production of fully printed collector lines by significantly increasing the material output of the system while continuing to reduce the width of printed lines to further
10% Efficiency Gain, at Lower Costs, for Crystalline Solar Cells
Recovery Act: Municipality of Anchorage, AK Energy Efficiency Conservaiton Block Grant Program:  The Municipal Facilities Retrofits Activity will implement energy-savings by retrofitting Municipal facilities and parking garages with lighting up
Recovery Act: Municipality of Anchorage, AK Energy Efficiency Conservation Block Grant Program
The City of Omaha will develop Energy EfficiencyConservation Strategy(EECS) to guide expenditure of Energy Effic Conserv Block Grant.EECS outlines City of Omaha energy efficient projects that will decrease the city's energy consumption & stimul
The City of New York's implementation plan for the use of Energy Efficiency and Conservation Block Grant (EECBG) funds incorporates a citywide, multi-sector approach to create a strong foundation on which to achieve the goals of the Long-Term P
Energy Efficiency and Conservation Block Grants (Formula)
Regulation and Administration of Communications, Electric, Gas, and Other Utilities
The Energy Efficiency and Conservation Block Grant dollars awarded from the Department of Energy will be used to advance the City of New Orleans' efforts to reduce the carbon footprint of the City as well as generate green jobs and rebuild sust
The Energy Efficiency and Conservation Block Grant Program
The purpose of this award is to implement the Recipient's Energy Efficiency & Conservation Strategy in order to reduce fossil fuel emissions; reduce total energy use of the eligible entitles; and improve energy efficiency in the building sector
The purpose of this grant is to advance clean technology and energy efficiency goals at the community level.   This grant will be administered through 4 major funding activities:  (1) More than 80% of the grant will be allocated to clean techno
Mass Energy Efficiency and Conservation Block Grant
Energy Efficient and Conservation Block Grants (EECBG) will enable cities and counties to perform energy efficient retrofits, system upgrades, and develop sustainable community initiatives.  MDA Energy Division will provide grants to cities and
Energy Efficiency and Conservation Block Grants
The City of Durham will use funds in two tracks: (1) improving energy efficiency and conservation in city-owned facilities and (2) developing and implementing a residential energy efficiency retrofit program.  Goals and objectives for this stra
Recovery Act: Durham Energy Efficiency and Conservation Block Grant Program
Orange County was officially awarded $7,522,900 from the DOE EECBG on September 15, 2009. The purpose of the project is to reduce fossil fuel emissions, reduce total energy use, and to improve energy efficiency in buildings, transportation and
RECOVERY ACT:  COUNTY OF ORANGE, FL ENERGY EFFICIENCY AND CONSERVATION BLOCK GRANT
Palm Beach County's Energy Efficiency and Conservation goals and objectives will be through an open bidding process final selection contingent upon Dept. of Energy approval to achieve the following: * Implementation of renewable energy technolo
Palm Beach County's Energy Efficiency and Conservation Project Activities
Energy Efficiency and Conservation Block Grant:  The purpose of this award is to implement Lake County's Energy Efficiency and Conservation Strategy in order to reduce fossil fuel emissions, reduce total energy use of eligible entities, improve
County of Lake, IL Energy Efficiency and Conservation Block Grant
The purpose of this award is to implement the City of Fort Wayne's Energy Efficiency and Conservation Strategy.
Recovery Act:  Energy Efficiency and Conservation Block Grant
The purpose of this grant is to support the implementation of the American Recovery and Reinvestment Act of 2009 in Arkansas through the Energy Efficiency and Conservation Block Grant (EECBG).  The goal is to assist eligible entities in creatin
This assistance agreement provides funding to the City of Phoenix Public Works Department under the American Recovery & Reinvestment Act of 2009.  This funding will enable the City to benchmark City facilities, coordinate energy audits and perf
Energy Efficiency and Conservation Block Grant Program
MINES MINERALS AND ENERGY, VIRGINIA DEPARTMENT OF
The funding is provided through the American Recovery and Reinvestment Act. Sixty percent of the funding will be targeted to smaller Virginia localities to develop and conduct energy efficiency programs and projects in areas such as EE&C strate
Recovery Act: State of Virginia Energy Efficiency and Conservation Block Grant
Energy Efficiency & Conservation Block Grant
Recovery Act: Energy Efficient Facilities     Project consists of energy conservation measures at the recently purchased Travis County Administration Building located at 700 Lavaca Street, Austin, Texas. This building is a 15 story office build
Energy Conservation Measures at 700 Lavaca
Development of a Sustainability Plan The City of Colorado Springs is developing a Sustainability Plan for the organization. A component of that plan uses technical consultant services to include a greenhouse gas emissions inventory of our munic
Recovery Act: City of Colorado Springs, CO Energy Efficiency and Conservation Block Grant
STATE OF COLORADO GOVERNOR'S ENERGY OFFICE
Fund energy efficiency and renewable energy programs and projects in small communities of 35,000 and less in Colorado.
Recovery Act: State of Colorado Energy Efficiency and Conservation Block Grant
The purpose of this grant is to provide sub-grants to 142 Connecticut Municipalities not elegible for direct grants from U.S. DOE under a formula grant program and to provide competitive opportunities for all 169 Connecticut municipalities to p
State of Connecticut Energy Efficiency and Conservation Block Grant
Clackamas County Energy Efficiency and Sustainability Program. An Energy Efficiency Conservation Strategy has been developed that establishes six specific energy efficiency activities.  These include a program to retrofit Clackamas County publi
Clackamas County Energy Efficiency and Sustainability Program
The purpose of this project is to enhance the development of ultra-high efficiency fuel cell systems including the market-ready Direct FuelCell (DFC) as well as the next generation Solid Oxide Fuel Cell (SOFC) system.  Implicit in this purpose
Development of a Microchannel High Temperature Recuperator for Fuel Cell Systems
Energy Efficiency improvements to Chickaloon Village Traditional Council Government/Health & Social Services Building
EECBG Tribal Energy Efficiency Improvements
The initial purpose of the program is to set up a small solar sytem inorder for the Tribe to become familier with how it functions.  As they beome more familier with the functions and the benefits, it will be easier for the Tribe to then invisi
Solar project for the Emergency Operation Center.
City of Mansfield Master Plan Design of an Advanced Traffic Management System to serve the existing and future traffic signal throughout the City.  The expected result of this system to the allow the City to have a central monitoring location f
Mansfield Signal Timing Design and Implementation and ATMS Masterplan Design
SOUTH CAROLINA OFFICE OF STATE TREASURER
The program is designed to provide rebates to customers purchasing certain Energy Star appliances.  The goal is to stimulate the economy by providing an incentive for residents to replace old, inefficient appliances with new energy efficient on
Recovery Act - State Energy Efficient Appliance Rebate Program
Appliance rebates program objective is to save energy by encouraging appliance replacement through consumer rebates, make rebates available to consumers, enhance existing programs by leveraging Energy Star national partnerships and local progra
Recovery Act- State Energy program for the Commonwealth of Virginia
The Wyoming State Energy Office (WYSEO) plans to utilize ARRA-SEEARP funds totaling $511,000 be used to implement and fund a mail-in rebate program administered through sub-contract to a qualified third party contractor.  The ultimate goal of t
State Energy Efficient Appliance Rebate Program (SEEARP)
ADMINISTRATION, RHODE ISLAND DEPARTMENT OF
The Energy Effecient Appliance Rebate Program objectives are to save energy by encouraging appliance replacement through consumer rebates; make rebates available to consumers; enhance existing rebate programs by leveraging ENERGY STAR national
Energy Efficient Appliance Rebate Program
Recovery Act: Caddo Nation Energy Efficiency Audit and Renewable Energy Implementation Program
EECBG for Confederated Tribes of Siletz Indians
Increasing Energy Efficiency in CTSI Residential, Government and Commercial Buildings
The purpose of this grant is  to provide funds to make energy efficiency upgrades in the Sanford Town Hall Annex.  These upgrades will result in reduced fossil fuel usage, reduced emissions and carbon footprint, and result in significant taxpay
Energy Efficiency Upgrades in the Sanford Town Hall Annex
The purpose of the State Energy Efficient Appliance Rebate Program (SEEARP) is to stimulate the sale of energy efficient appliances and decommission existing high consumption home appliances.  Appliances eligible for the first section of progra
State Energy Efficient Appliance Rebate Program
The Appliance Rebate Program Objectives are:  1. Save energy by encouraging appliance replacement through consumer rebates, 2.  Make rebates available to consumers, 3.  Enhance existing rebate programs by leveraging ENERGY STAR national partner
INSTALLATION OF SOLAR PANELS CELLS ON THE ROOF OF CITY HALL BUILDING TO GENERATE ENERGY
INSTALLATION OF SOLAR CELLS ON CITY HALL BUILDING
Electric Lamp Bulb and Part Manufacturing
The objective of this project is to manufacture and distribute a zero tailpipe emission light duty commercial electric vehicles (EV) to the United States.  Navistar shall develop and demonstrate at least 950 commercial medium duty EVs (Class 2c
Commercial Electric Vehicle (EV) Development and Manufacturing Program
Texarkana, Texas Energy Efficiency and Conservation Strategy  The strategy will cover local government operations and the entire Texarkana community. The strategy will identify opportunities to minimize energy use and cost, increase the use of
Texarkana, Texas Energy Efficiency and Conservation Strategy
Building retrofits for eight township buildings, energy audits for eight township buildings and a comprehensive energy plan from Rutgers EJ Bloustein.
award of energy funding to improve energy efficiency in public schools
Complete Climate Action Plan Offer residential home energy audits and referrals Replace streetlights with energy efficient lights
Clmate action plan, home energy audits and street lights
Energy Efficency and Conservation Block Grant Program
Replacement of the lights of traffic signals with LED lights, replace lighting fixtures in five facilities and, an building energy retrofit. Replace windows at City Hall with energy efficient windows. Grant admnistration costs.
City of Kearney Transportation and Energy Efficiency Program
Retrofit building with new boiler and energy efficient lights
Other Services to Buildings and Dwellings
Energy Efficiency grant to allow the replacement of inefficient heating units at Streamwood Village Hall
These funds may be utilized to implement programs or projects that results in establishing energy efficiency and conservation
Establish Li-Ion Battery Pack manufacturing facility in Brownstown, Michigan.  Activities include the procurement and installation of equipment and tooling, manufacturing engineering, manufacturing process and battery pack build validation, wor
Assistant Secretary for Energy Efficiency and Renewable Energy
ENERGY EFFICIENCY FOR A MORE SUSTAINABLE ROSEVILLE
The City of Cypress used awarded Energy Efficiency and Conservation Block Grant (EECBG) funds to offset the costs incurred to replace an outdated and inefficient Heating Ventilation and Cooling (HVAC) system that has served the Cypress City Hal
retrofit of Air handler for City Hall Annex
retrofit of Air Handler in City Hall Annex
The City of San Luis Obispo's Energy Efficiency and Conservation Strategy consists of meeting goals and accomplishing programs defined in the City's General Plan, the U.S. Mayors Climate Protection Agreement endorsed by the Council in 2005, for
San Luis Obispo - Energy Efficiency and Conservation
The program provides financial and technical assistance to State and local governments create and implement a variety of energy efficiency and conservation projects. The program's objectives are : 1) To reduce fossil fuel emissions created as a
Energy Efficiency and Conservation Block Grant (EECBG)
Material Conservation includes Human Resources software, Click2Gov Core Module, Click2Gov for online job applicants and training fees. The Energy Retrofits include lighting upgrades to City facilities, recyling bulbs and ballast, purchasing HVA
Material Conservation and Energy Efficiency Retrofits
Retrofit Street Lights, retrofit 2 municipal buildings: conduct energy audit at Town Library
HOUSING AUTHORITY OF THE CITY OF BRIDGEPORT
Comprehensive modernization of various public housing developments to include:  * modification of a parking lot and walkway replacement, installation of fencing, lighting and overhead walkway canopy to comply with 504 accessibility requirements
Conduct modernization activities at Public Housing Communities. Should opportunity present itself, the Auhtority may re-program thses funds (revise the grant) to federalize existing properties in its state housing portfolio.
Conduct modernization activities at various public housing communities. This funding can be expected to result in providing employment for architects, engineers, construction workers, and product manufacturers. In addition this funding can be e
Public Housing Captial Fund Stimulus (Formula) Recovery Act Funded
1) Capital Needs Assessment to confirm most reasonable use of ARRA funding 2) Contracted services for roof replacement project for 4 buildings, encompassing 11 public housing units: Removal of existing shingles, roof deck, rotted plywood, trim,
This ARRA grant provides $493,947 of Section 5309 Fixed Guideway Modernization -American Recovery and Reinvestment Act (ARRA) funds for the replacement of one 45-ft commuter express over the road coach bus operating in the Hartford region along
ARRA Section 5309 - Purchase of one Commuter Express Bus for the Hartford Region.
This Road Repair and Restoration project is located 2 miles east of Lodgepole and extends south to the intersection with State Highway 191. The Pavement on this route is in severe distress and therefore, no pavement preservation activities will
The project is 0.7 miles long and consists of rehabilitation of the paved surface and safety improvements along the entire road corridor. The safety improvement portion of the project will include removal of any obstructions in the right-of-w
This 2.1 mile long project consists of rehabilitation of the paved surface and safety improvements within the road corridor. The safety improvement portion of the project will include removal of any obstructions in the right-of-way, repair righ
This project is located on BIA Route 114 starting at the reservation boundary and proceeding south to Bear Paw Ski area. The project consists of a rehabilitation of the paved surface and safety improvements along the entire road corridor. The p
The Project will provide for the surface renovation of approximately 14.8 miles of Indian Service Route 18, the Ponemah Road, from Minnesota Trunk Highway No. 1 North to Sucker Creek near the village of Ponemah, Minnesota and 0.3 miles of India
Construction of single famiy homes for low income families
ARRA Fuels Project; pile and remove biomass on the reservation.
Repair Building 204-Sewage Pump Station, IMCOM
Upgrade Electrical Systems, Repair Gutters, OMB Project #38915, Army Family Housing Residences 5 and 8 added to Gutter Replacement and Gutter Guard Supply/Installation under CLIN 0006CE awarded on a Firm Fixed Price basis.
ARRA Notice 43 - The scope of work for this modification is to restore all services as originally required which includes the restoration of manpower, materials, supplies & operating expenses. ARRA Notice 45 - The scope of work for this modific
ARRA Notice 44 - The scope of work for this modification is for Invasive Plant Species Control and includes the installation of a farm type fence, approximately 3,910 lineal feet in addition to providing goats for invasive species control.
dated April 8, 2009. Tasks 1 through 4 of the SOW are awarded at this time (120 days of dredging operations). The work to be performed primarily consists of dredging, desanding, dewatering and wastewater treatment necessary for the remediation
We are requesting funding for the creation of a next generation sequencing center, dedicated to plant genomics.  Such centers were recently called for by a report on the plant genome project by the National Research Council.  We will use the fa
MRI: Acquisition of Next Generation Sequencers
Rehabilitation of 2 Scattered Sites units.  Activities to be funded by the CFRC grant:  In order to achieve a reduction of 35% or more of energy/water consumption, the following activities will be funded by the CFRC grant:  ? Energy Star© 93%
The Arthur Capper Carrollsburg project is a formerly blighted and severely deteriorated public housing community comprised of the former Arthur Capper Family, Arthur Capper Senior, and Carrollsburg public housing developments located in the Sou
Replacement of fifteen old and inefficiant HVAC units at 145 West B. st. and 115 North Ada st. Fallon Nevada, 89406 with highley those have twice the SEER rationg of those removed.
The National Synchrotron Light Source (NSLS) II is a major scientific user facility being constucted at Brookhaven National Laboratory to deliver x-rays with unprecendented intensity and brightness as probes for solving some of the most importa
Geothermal Technologies Program Enhanced Geo Science R&D 1) CPS #20007 (Project-Base Technologies-144299) Design, develop, and field test highly integrated, high temperature data loggers using silicon on insulator and silicon carbide technologi
Smart Grid Investment Grant Program SNL will provide technical assistance to the Office of Electricity Delivery and Energy Reliability, specifically for the Smart Grid Investment Grant program as requested.
JEFFERSON SCIENCE ASSOCIATES, LLC, A SURA/CSC COMPANY
Nuclear Physics - Enhanced AlP funding at NP user facilities (2005220), KB/OR39/9/ ARRA-4:  This Work Authorization is issued for the sole purpose of authorizing work in support of the American Recovery and Reinvestment Act of 2009, (Pub. L. 11
57402 - Title:  Land-Use Change Modeling Studies  Purpose:  The purpose of the project is to improve land-use change modeling capabilities to help ensure biofuels can be produced sustainably  Description:  The project will Increase the scope of
Award Title: Recovery Act ? Greenhouse Gas Tools and Resources Support  Award Purpose: To have FEMP develop and provide comprehensive GHG management and abatement services to Federal agencies as they begin to focus attention on mitigating clim
The overall purpose of this effort is to provide technical programmatic assistance to the National Energy Technology Laboratory's (NETL's) Project Management Center (PMC) to support implementation of the ARRA.  The scope of this work will be fo
Support DOE  in the preparation of 8 environmental assessments to access the potential for impacts to the environment as a result of DOE's participation in a coop agreement with BASF.
TECHNOLOGY AND MANAGEMENT SERVICES, INC.
Support to the offices of the Loan Guarantee Program and the Chief Financial Officer.
JONES AND COMPANY PROFESSIONAL CORPORATION
Project Facilitator, to support ESPC efforts for the US Capitol project.
Black flies are a worldwide group of more than 2,000 species of medically important, blood-feeding insects that breed in flowing water. They are structurally similar and many species, known as cryptic species, defy distinction under the microsc
Discovery and Predication of Hidden Biodiversity in Black Flies
The islands of the Southwest Indian Ocean are renowned for exceptional biological diversity and high concentrations of endemic species. A complex process of continental fragmentation, island emergence and habitat isolation has produced a unique
Collaborative Research: Ants of the Southwest Indian Ocean and East Africa (ASWEA): assessing phylogenetic diversity   and biogeographic linkages across the Mozambique Channel
Some of the most compelling questions in evolutionary biology relate to the origin of our own species.  Fossil and genetic data have provided incredible insights into human evolutionary history, and yet there are many important questions left u
Career: Population genetics of Pediculus humanus using coalescent approaches with multi-locus data.
Despite numerous ecological and behavioral studies focusing on Neotropical cichlids, Heroini, the largest tribe comprising 160 nominal species, has received little taxonomic attention. Heroini includes many well-known fishes kept as pets (e.g.,
REVSYS:  Reconstructing Heroini (Teleostei: Cichlidae) - Of Heroes, Convicts, Angels and Red Devils
Louisiana State University Museum of Natural Science
Intellectual merit. Elucidating the causes and consequences of polyploid evolution is central to understanding the origin and diversification of most lineages of eukaryotes. Polyploids experience the combined challenge and potential of having t
Collaborative Research: Genome Evolution in Natural Populations and Synthetic Lines of Allopolyploids in Tragopogon
Title: Competition and the origins of diversity: Experimental evolution of resource polymorphism, character displacement, and reproductive isolation in viruses  Project description: A central goal of evolutionary biology is to explain why livin
Competition and the origins of diversity: Experimental evolution of resource pol
Booz Allen Hamilton will assist with conducting and coordinating all aspects of finance, accounting, loan valuation, and collateral and credit analysis for the Advanced Technology Vehicle Manufaturing Loan Program (ATVM).
SMS will provide the necessary resources and technical capability to provide management support to the DOE Office of Electricity Delivery and Energy Reliability (OE) in conducting the 2009 Smart Grid Investment Grant Program FOA application mer
The purpose of this contract is to develop the Performance and Accountability for Grants in Energy (PAGE) module for the Energy Efficiency Block Grant Program. This solution provides DOE grantees a web-based tool for gathering and submitting t
Energy Efficiency and Conservation Block Grant Program. The City of Grand Island has completed an Energy Efficiency and Conservation Strategy that proposes the completion of three activities to improve energy efficiency and reduce energy costs
Energy Efficiency Conservation Strategy for the City of Grand Island, NE
Energy Efficiency and Conservation Block Grants - Formula Grants
City of Brookfield Public Safety Building Energy Conservation and Sustainability
Replace utilities and conduct retrofits on municipal building, and replace traffic signal lights.
Replace utilities and conduct retrofits on municipal buildings, & replace traffic signal lights
This is a Firm Fixed Price Task Order in accordance with the terms and conditions set forth in the Basic Contract DE-EM0000156. The contract is for one full-time equivalent (FTE) at the Progam Manager III level to serve as support at the Richla
500-SREL will organize a series of short courses on technical topics for SRS environmental professionals /501-SREL is developing an automated stream monitoring system that responds to transient flow conditions in a manner designed to evaluate t
Managing distribution system resources for improved service quality and reliability, transmission congestion relief, and grid support functions. Amendment 001 involves the awarding of funds from the American Recovery and Reinvestment Act of 200
Smart Grid Regional and Energy Storage Demonstration Project (EISA 1304)
The project demonstrates a novel concept for CO2 compression using supersonic shock wave compression technology.  Ramgen will demonstrate the simultaneous potential of shock wave compression to achieve high compression efficiency and high stage
Design and Testing of Ramgen Supersonic Shock Wave Compression and Engine Technology.
Weatherization Assistance Program, Recovery Act
EECBG Grant for energy efficiency program.
To provide services to the Office of the General Counsel with specialized legal advice and services (a) on programmatic aspects of the ATVM Program and (b) on transactions proposed or consummated under the ATVM Program.  The services to be perf
The funds will be used to hire or retain staff and expand state level capacities to address challenges to the country’s energy systems, including emergency situations such as blackouts, hurricanes, ice storms, and disruptions to heating suppl
Recovery Act - Enhancing State Gov't Energy Assurance Capabilities & Planning for Smart Grid
This initiative focuses on developing new (or refining existing) plans to integrate new energy portfolios (renewables, biofuels, etc.) and new applications (Smart Grid technology, etc.) into energy assurance and emergency preparedness plans.
Energy Assurance Planning - State of Washington
This initiative, called The Enhancing State Government Energy Assurance Capabilities and Planning for Smart Grid Resiliency Initiative (hereinafter called the State EA Initiative) focuses on developing new, or refining existing, plans to integr
Enhancing Arkansas State Government Energy Assurance Capability and Resiliency Planning
Recovery Act Energy Assurance Planning - Nevada
Recovery Act- Energy Assurance Planning - Nevada
GOVERNOR'S OFFICE OF ENERGY INDEPENDENCE AND SECURITY
This project will allow Maine to expand and enhance its in-house expertise in energy emergency planning while encouraging continued collaboration between agencies and update the States Emergency Energy Plan.
Recovery Act - Energy Assurance Planning - State of Maine
Office of Electricity- Recovery Act Energy Assurance Planning- State of Oklahoma.  The objective of this initiative are to: 1) strengthen and expand State and local government energy assurance planning and resilency efforts by incorporating res
Recovery Act-Energy Assurance Planning-State of Ohio. Block 9 Authority: PL 95-91 DoE Organization Act, PL 111-5 American Recovery and Reinvestment Act of 2009 and PL 109-58 Energy Policy Act 2005
Enhancing State Government Energy Assurance Capabilities and Planning for Smart Grid Resiliency
Clean Cities FY09 Petroleum Reduction Technologies Projects for the Transportation Sector
Incremental Costs of Dedicated Alternative Fuel Vehicles (AFV's)
Title: Recovery Act - Efficiency & Conservation Block Grant Program  Grant funds will be specifically utilized to replace eleven (11) inefficient HVAC systems in the Town's larger municipal buildings.  The total cost of HVAC replacement is $298
Recovery Act - Efficiency & Conservation Block Grant Program
City of Commerce City Energy Audit Program and Develop Energy Efficiency/Conservation Plan
Recovery Act-Energy Eficiency & Conservation Block Grant
Missoula County, Montana will reduce energy consumption, reduce greenhouse gas emissions and create jobs with a series of energy efficiency retrofits on county owned buildings. Deliverables: Deep Well Ventilation system on County Courthouse, a
Recovery Act - Energy Efficiency and Conservation Block Grant Program
Office of Civilian Radioactive Waste Management
Latah County is proposing to use the bulk of these grant funds for energy efficiency retrofits on public facilities to capitalize on energy savings and cost reduction and reinvest these savings in ongoing energy efficiency upgrades and public i
Replacement and Upgrade of Boiler at Latah County Courthouse
Energy demand reduction of approximately 364,044 kwh/yr through upgrades to HVAC systems at two City facilities and implementation of a virtural server environment.
Park County, Wyoming is seeking funding through the Energy Efficiency and Conservation Block Gant program to replace two boilers in a large County-owned public building.  Park County purchased the building in 2005 to house county offices and a
The City of Boulder City will be replacing approximately 100 street lights on Adams Blvd. between Buchanan Blvd. and Utah St.  The existing lights are half 400W mercury vapor and the other half are 250W high pressure sodium.  These lights draw
Street Light Efficiency Improvement Project
Recoveru-Energy Efficiency & Conservation Block Grant Program
Recovery=Energy Efficiency and Conservation Program
RECOVERY ACT-ENERGY EFFICIENCY & CONSERVATION BLOCK GRANT PROGRAM
Recovery Act--Energy Efficiency and Conservation Block Grants--Formula Grants--funding will be used for energy efficiency upgrades a community parking garages which will result in energy savings, installation of a Compressed Natural Gas fueling
City of Grand Junction Energy Efficiency and Conservation Block Grant Strategy
The overall purpose of the award is to facilitate 3 major energy efficient projects on County facilities.  (!)  The Highway building project will consist of insulating the primary shop area ceiling and constructing a pitched roof on the from
Lake County Facilities Energy Conservation Upgrades
ENERGY EFFICIENCY AND CONSERVATION BLOCK GRANT - FUNDS TO BE USED FOR LIGHTING RETROFIT AT CITY FACILITIES AND FOR PURCHASE AND INSTALLATION OF TRAFFIC SIGNALING CENTRAL CONTROL SYSTEM
Multiple energy upgrades to various government ran facilities in Putnam County.
Multiple energy upgrades in Putnam County, WV
The Ramsey County Courthouse project is to increase energy efficiency and reduce energy consumption.  The project is in three parts.  Part 1 recaulk 456 openings.  Part 2 replace 23 single hung windows, add sill plates, drip caps.  Part three i
Municipal Buildiing Upgrade of the City's heating system and installation of tankless water heaters. This award has been amended to add installation of energy efficient lights to the exterior of the Municipal building.
Energy Efficiency Conservation Block Grant
Energy Efficiency retrofit of the City Park Shop
Energy efficient retrofits for Canyon County, Idaho
Energy Efficiency and Conservation Block Grant for Photovaltaic System, LED light fixtures, LED street lights and marketing activities.
Draper City Photovaltaic System, LED light fixtures, LED light in City Hall, Energy Efficiency Marketing
Goals for this grant are to: Encourage Energy Efficiency Move towards clean mobility Engage the Community in Sustainability
Home Energy Reporting System;EEGCB Pre-Award Application Preparation and General Support;Lighting Controls in Sammamish City Hall;Program Management, Administration and Reporting;City of Sammamish Sustanability Strategy;Vehicles Upgrades.
Energy Efficiency and Conservation Block Grant to facilitate construction of 65kW photovoltaic solar energy system at the City of Cerritos Corporate Yard.
Installation of a photovoltaic solar energy system at the Cerritos Corporate Yard
EE Conservation Block Grant Program. Development and Implementation of a Comprehensive Energy Strategy and solar field to save energy costs at the Emergency Operations Center.
EE Conservation Block Grant Program 2004350
Funding to implement the approved strategy
The City of Clifton has retained First Environment, Inc. an environmental consulting and engineering firm to assist the City in development of a long-term plan and comprehensive strategy for leveraging existing funds, plans and programs. First
EECBG Photovoltaic Project for Washoe County, NV
Structural Steel and Precast Concrete Contractors
Energy Efficiency and Conservation Block Grant (EECBG) To improve the energy efficiency of the City of Corona by retrofitting existing street lights with induction lighting technology and installing solar panels at Water Reclamation Facility #1
Project 1) Traffic and Safety Lighting Induction Retrofit and Project 2) On-site Renewable Energy Through Solar Panel Installation at Water Reclemation Facility #1
Improvements to services and properties for energy conservation including purchase of more efficient signal lights, energy efficient HVAC units, energy efficient chillers, and conversion to LED street lights where applicable
Award utilized to develop an energy strategy for the city through the services of a consultant agency.  (Completed December, 2009).  The activities to be followed, based upon the strategy plan include energy audits, lighting upgrades, HVAC upgr
New award for City of Garden Grove to install PV solar structure.
The City of Downey plans to use EECBG funds for the Capital Improvement Energy Efficiency Retrofit Program. The Capital Improvement Energy Efficiency Retrofit Program goals are to improve existing buildings and facilities, lower the City's ener
Capital Improvement Energy Efficiency Retrofit Program
Energy Efficiency and Conservation Block Grant - Formula Grant
EECBG for the City of Clovis, CA  Lighting Retrofit Project, HVAC Upgrade Project, Computer Energy Efficiency Software Project
Commercial, Industrial, and Institutional Electric Lighting Fixture Manufacturing
The City of Merced will establish an energy efficiency strategy program, including a climate action plan, Community Energy Investment Fund, Green Fleet program, and complete energy retrofit of city facilities and assets.
Energy Efficieny and Conservation Development
Project #1 Lighting Upgrade, to replace old light fixtures in county facilities. Project #2, Air Quality Improvement, replacing very old coolers with energy efficient units  while reducing energy consumption. Project #3 Data Center Upgrade, rep
#1 Lighting Upgrade Plan, #2 Air Quality Improvement, #3 Data Center Upgrade, #4 Employee Energy Savings Program
2004350 - EE CONSERVATION  BLOCK GRANT PROGRAM
ENERGY EFFICIENTY & CONSERVATION BLOCK GRANT
The Energy Efficiency and Conservation Block Grant (Formula Grants) assists local governments in creating and implementing strategies to: reduce fossil fuel emissions; reduce the total energy use; and improves the energy efficiency in the build
Energy Efficiency and Conservation Block Grant (Formula)
Energy Efficiency and Conservation Block Grant, used to implement 5 activities, including Signal Optimization, District Energy Study, 86th Street Multi-modal study and implementation, and Bloomington Ferry Road Multi-use trail.
Signal Optimization, District Energy Study, 86th Street Multi-modal study and implementation, and Bloomington Ferry Road Multi-use trail
2004350 - EE Conservation Block Grant Program
Porter County Energy Conservation Program
This project is to study the connectivity and flow patterns of complex multi-scale systems modeled as random networks.  Networks provide effective ways to study global, system level properties, starting with local, multi-scale interactions at a
Robust Optimization for Connectivity and Flow Patterns in Complex Dynamic Networks
Jim Warren Park Field and Street Lighting Efficiency Improvements and hiring of Sustainability/Grant Coordinator
Sustainability/Grant Coordinator and Jim Warren Park Lighting Efficiency Upgrades
In recent years, network bandwidth requirements have scaled multiple folds, pushing the need for the development of data exchange mechanisms at 100 Gb/s and beyond. The main objective of this project is to implement a high performance HyperTran
TAS::89 0227::TAS RECOVERY; NEW; RECOVERY ACT - End-System Network Interface Controller for 100 Gb/s Wide Area Networks
Implementing upgraded technoclogy to government buildings making them more energy efficient, also to reduce total energy use, and to improve energy efficiency in the transportation, building, and other appropriate sectors.
Implementation of Energy Efficiency and Conservation Program
09 (ARRA) Energy Efficiency and Conservation
The program provides financial and technical assistance to assist state and local governments create and implement a variety of energy efficiency and conservation projects. The program objectives are: * To reduce fossil fuel emissions created a
Ignacio Arzuaga St. Intersection Fernandez Juncos Ave.
First installment of $250,000.00 for EECBG energy conservation block grant. First phase for strategy development. $1,046,800.00 award to the City of South Bend, Indiana. Second grant draw in the amount of $654,372.00 received 10/15/10.Final gra
Activity Description:  Development of an Energy Efficiency and Conservation Strategy (EECS). The City of Carrollton has requested $237,820 (20% of its total grant allocation) to develop an Energy Efficiency & Conservation Strategy that is align
Implement Energy Efficiency and Conservation Strategy
Energy Efficiency and Conservation Block Grant funding for energy retrofits in municipal buildings. Retrofits will include HVAC upgrades, building automation systems and lighting upgrades. Several parks will also get lighting upgrades. These fu
ENERGY EFFICIENCY AND CONSERVATION BLOCK GRANT PROGRAM
Energy Efficiency and Conservation Block Grant - The City of Independence will use this grant for 8 different activities to carry out the City of Independence energy Efficiency Initiative.  The eight activities in the initiative include energy
The City Portsmouth plans to: 1) retrofit four city owned parking garages with energy efficient lighting and lighting control systems to reduce energy usage and associated carbon emissions by 35%. 2) synchronize the operation of the city's 94 s
Energy Efficiency and Conservation Block Grant - Portsmouth, VA
Energy Efficiency and Conservation Block Grant - City of Santa Maria, CA The City of Santa Maria proposes to retrofit the City-owned Parking Structure A at the Town Center East Mall in downtown Santa Maria. The project will apply an array of en
Energy Efficiency and Conservation Block Grant - City of Santa Maria, CA
This grant provides funding from the U.S. Department of Energy (DOE), specifically for State Energy Programs, to be used for energy efficiency and renewable energy purposes. Consistent with the goals of the DOE State Energy Program, Utah SEP se
ARRA State Energy Program Formula Grant (Funding Opportunity Number: DE-FOA-0000052)
Michigan Department of Human Services has been awarded stimulus funding from the U.S. Department of Energy Weatherization Assistance Program for Low-Income Persons in the amount of $250 million dollars over the next three years.  The State plan
Recovery Act Weatherization Award for the state of Michigan
The State Energy Program (SEP) project includes energy efficiency activities and incentives that involve retrofitting government buildings, greening the building codes and educating residents, schools, businesses and faith based entities.
The program provides financial and technical assistance to State governments to create and implement a variety of energy efficiency and conservation projects in order to provide leadership to maximize the benefits of energy efficiency and renew
THE WEATHERIZATION ASSISTANCE PROGRAM ENABLES LOW-INCOME FAMILIES TO PERMANENTLY REDUCE THEIR ENERGY BILLS, MAKING THEIR HOMES MORE ENERGY EFFICIENT.
ARRA Supplemental Funding for the Weatherization Assistance Program (WAP): To reduce energy costs for low-income families, particularly for the elderly, people with disabilities, and children, by improving the energy efficiency of their homes w
Weatherization Assistance for Low-Income Persons.
The Weatherization Assitance for Low Income Persons Program works to increase the energy efficiency of dwellings owned or occupied by low-income persons, reduce their total residential expenditures, and improve their health and safety.
Weatherization Assitance for Low Income Persons Program
Hawaii's primary energy goal is to reduce the State's high dependence on oil while providing adequate and secure energy supplies at reasonable cost.  The objective of the Hawaii Clean Energy Initiative is to obtain 70 percent of Hawaii's energy
To promote energy efficiency and advocate the use of renewable energy technology for the residents of the Virgin islands through capital investments, energy education, financial incentives and technical assistance in ordr to increase energy sav
Virgin Islands State Energy Program ARRA Plan: to promote energy efficiency and advocate the use of renewable energy technology for the residents of the Virgin Islands
The State Energy Program will provide funding for six initiatives in the State of Rhode Island -- The RI building Energy Code Upgrade, Training and Compliance Initiative will train state and local elected officials and other stakeholders includ
Fuel Cell Hybrid Power Packs and Hydrogen Refueling for Lift Trucks - H.E. Butt Grocery
All Other Miscellaneous Electrical Equipment and Component Manufacturing
The objective of the project is to evaluate a novel concept to doubling the efficiency of thin film photovoltaics (PV) while benefiting from the advantage of thin film manufacturing by use of less material and roll-to-roll continuous processing
Near-Single-Cyrstalline Photovoltaic This Films on Polycrystalline, Flexibile Substrates
The Automotive X PRIZE (AXP) Education & Outreach Program (the Program) will use the X PRIZE Competition technical design and vehicle demonstrations as a means of attracting students and the public to learn more about advanced vehicle technolog
Recovery Act - The Automotive X PRIZE Evaluation, Education, and Outreach Program
Funding to undertake energy conservation in county owned public facilities in Cuyahoga County, conduct energy audits of local municipal government structures with funding to make energy saving retrofits to identified energy losing facilities, a
Recovery Act EECBG: Go Green Louisville is Louisville-Jefferwson county Metro Government's focusing on: 1) Building energy audits and retrofits; 2) Financial incentive programs; 3) Installation of energy efficient traffic signals and street lig
Recovery Act: Prince George's County, MD Energy Efficiency and Conservation Block Grant.
Develop the Countywide Energy Efficiency and Conservation Strategy (EECS) and conduct other 11 energy efficiency and retrofit projects/activities.
MEA is using our EECBG funding to enable sub-grants to Maryland counties, cities, and towns that are not receiving EECBG grants directly from DOE.  The sub-grants will be used to enable energy efficiency and renewable energy technology on facil
Energy Efficiency and Conservation Block Grant Program Activities
Energy Efficiency and Conservation Block Grant Program.  To encourage communities to reduce the use of fossil fuels, reduce energy consumption, promote green jobs and businesses.
Energy Efficiency and Conservation Strategy planning and development
Energy Efficiency and Conservation Block Grant  The activities funded by this award will add to the previouly implemented activities that are summarized in the following paragraph.  Since the Energy Management program started, Hillsborough Coun
Lake County has been awarded $2,807,500.00 under the American Recovery and Reinvestment Act (ARRA) Energy Efficiency and Conservation Block Grant (EECBG) Formula Grant Program (U.S. Department of Energy, Office of Energy Efficiency and Renewabl
County of Lake, FL Energy Efficiency and Conservation Block Grant
Activity 1: Energy Conservation Measures - Replace Roof and Insulation at South County Jail Activity 2: Install energy conservation measures in seven County buildings
Arizona Revised Statute 49-474.03 states, 'A county with a population of more than four hundred thousand persons …shall operate and administer a voluntary vehicle repair and retrofit program in the County.'  Maricopa County coordinated the Vo
Maricopa County Voluntary Vehicle Repair & Retrofit Program/Solar Thermal Water Heating
Maricopa County Green Government Program
The balance of Arizona's State Energy Efficiency and Conservation Block Grant (ABS-EECBG) Program assists eligible local government entities to develop, promote, implement, and manage energy efficiency and conservation projects and programs des
Recovery Act: State of Arizona Energy Efficiency and Conservation Block Grant
The City of Norfolk's award for the Energy Efficiency Block Grant Program has four primary components as described below:  The EVERGREEN ENERGY EFFICIENCY RETROFITS activity supports the installation of cooling towers for the Central Energy Pla
City of Norfolk EECBG Recovery Act Program
Denver will use EECBG funding to build upon existing programs to reduce community energy use and greenhouse gas emissions, such as the Greenprint Denver Action Agenda and the City's Climate Action Plan.  Funding will be used to implement energy
Denver Energy Efficiency and Conservation Block Grant Program
Energy Efficiency and Conservation Block Grant Program provides funds to reduce energy use and fossil fuel emissions through energy efficiency improvements and related activities. Bexar County was allocated $2,434,500 for this project. Initial
Strategy Development and four projects: 1) Bexar County Courthouse Weatherization. 2) San Antonio Food Bank -Energy Conservation Irrigation Project. 3) Leon Valley Sr Center Solar Retrofit. 4) GRASP Renewable Energy Retrofit
Bexar County Department of Community Resources
Delaware County (PA) continually strives to make its own operations as efficient as possible while encouraging energy efficiency and conservation among residents and individual municipalities, and thus the County has developed a thorough and co
Recovery Act: County of Delaware, PA Energy Efficiency and Conservation Block Grant
Energy Efficiency Upgrades and Retrofits
Residential and Commercial Building Energy Audits:  Entities may support the conduct of residential and commercial building energy audits.
RECOVERY ACT: NATIVE VILLAGE OF KWINHAGAK'S RESIDENTIAL AND COMMERCIAL BUILDING ENERGY AUDITS
1.The Tribe will install 10 solar panels and will receive training on the construction and installation of the panels. TheTribe will install 2 wind turbines to assist in the production of electric power on the Reservation.
Using Renewable Energy technologies on tribal buildings
Replacing Mercury street lamps with higher efficiency bulbs, replacing incandescent traffic signal bulbs with LED efficiency bulbs
Replacing mercury vapor street lamps with higher efficiency bulbs and replacing incandescent traffic signal bulbs with LED efficiency bulbs.
The Prairie Band Potawatomi Nation will propose to a contract vendor to design, install, and commission an alternative energy system to produce electricity to supplement power from the grid.  The Photovoltaic system will consist of approximatel
Prairie Band Potawatomi Nation Alternative Energy Project
Recovery Act:  Tribal Building Energy Efficiency and EECS Development.  The Tribe will replace energy inefficient windows in the tribal buildings with energy efficient double pane windows.
The Klamath Tribes propose to conduct comprehensive energy audits on Klamath Tribal buildings to determine the needs and capacities of the facilities.
Klamath Tribes Facilities Energy Efficiency Project
To implement the installation of a more efficient solution to the City of North Platte, Nebraska's traffic control system.  North Platte will change to LED bulbs to conserve more energy and reduce costs of maintenance and improve traffic, which
Traffic Signal Control System-Energy Efficiency and Conservation Block Grant Program
ANTHC was awarded DOE energy money on behave of 17 Federally recoginized Tribes.  The grant is to complete the following: 1). Conduct audits for the 17 Tribal communties in rural Alaska consisting of all Tribal, Heathcare and Water and Sanitary
Energy Efficiency Conservation Block Grant Program
Energy Efficient Lighting and Traffic Signal Retrofits
Do conservation strategy and purchase equipment for energy effeciency.
The $209,300 grand award will be used by the City to continue meeting & completing objectives within our existing Sustainability Policy. These monies will be used for the purchase of energy efficient lighting upgrade/retrofit materials for (14)
Lighting Upgrades and Retrofits for (14) City of Hickory Facilities.
This award will be used to install a Photovoltaic System (PV) on the City Hall building. The proposed 15 kw PV System is expected to use 937.5 sq ft. of roof area to generate approximately 2274 KWH monthly, reduce the building grid energy consu
Energy Efficiency and Conservation Block Grant Program (EECBG)
EECBG award to the Charter Township of Commerce, MI for the development of a multi-modal, non motorized public bike and park trail.  This will promote awareness of energy conservation, better health to the public and less dependency upon fossil
EECBG program funds used to reduce energy consumption in the Florence Municipal Building through performance contracting.
HVAC Control and Lighting Retrofit for City Hall Municipal Building
This grant will partially cover costs associated with developing a design, and installing per the design, a biomass boiler in the Walatowa Visitor's Center on the Pueblo of Jemez in northern New Mexico.  The boiler will be fueled by cord wood h
DEVELOP THE PONCA TRIBE OF NEBRASKA'S STRATEGIC ENERGY EFFICENCY AND CONSERVATION PLAN.
Energy Efficiency Conservation Block Grant (EECBG) was awarded to retrofit streetlights.  These retrofits are expected to reduce energy use by up to 60% an will result in significant cost savings for the City.
Retrofit 7 government buildings to increase energy eficiency.
The city will replace incandescent and fluorescent emergency exit lighting fixtures and replace aluminum framed single pane windows.Also replacing halogen lighting with induction lighting.
The funds offered by the Energy Efficiency & Conservation Block Grant (EECBG) will enable the Alabama Quassarte Tribe (AQ) to complete an energy efficiency and conservation review of a group of tribally owned buildings, and complete as much of
Serve on Merit Review Panel for Grants to Hydropower Development
1. Retrofit with tinted windows at City Hall. 2. Retrofit with high efficiency lighting at two parking garages.
Retrofit with High Efficiency Lighting & Tinted Windows
Creation and Implementation of EECBG Strategy for poles replacement for energy efficiency poles.
EECBG Creation and Implementation of EECBG Strategy
Award for the City of San Dimas to develop an Energy Efficiency Long-Term Strategic Energy Plan, GHG Inventory, Median Landscape Water Conservation Retrofits and Energy Retrofits to the San Dimas Senior Center lighting system.
Retrofit Packard Music Hall for energy efficiency including boiler system and window replacement.
ENERGY RETROFIT OF PACKARD CITY MUSIC HALL
The City of North Lauderdale is in the processing of expending EECBG funds to carry out energy retrofits in an effort to make operations in and around City buildings more energy efficient. So far, we have replaced two high-consumption vehicles
Energy Efficiency and Conservation - Project ID 2004350
The Program provides financial assistance to local goverments to create and implement a variety of energy efficiency and conservation projects. The program objectrives are: to implement and exchange the municipality recycling program for the co
Energy Efficiency & Conservation Block Grant Program (EECBG)
Technical Consulting and energy efficient equipment for heating and cooling.
Technical consulting and energy efficient retrofits
Jicarilla Apache Nation project to develop an energy strategy and conduct energy audit.
Jicarilla Apache Nation Proj. to Develop and Energy Strategy and Conduct Energy Audit
Energy efficiency and conservation improvements on municipal facilities
The Village of Downers Grove will use federal funding to support two projects.  The first project will support the retrofitting of several municipal buildings with solar furnaces.  An energy audit proved that the Village's Public Works building
This is a Time-and-Materials task order in accordance with the terms and conditions set forth in the Basic Contract DE-EM0000156. The contract is for one full-time equivalent (FTE) to serve as support for the DOE EM Recovery Act Project to incl
This is a Time-and-Materials order in accordance with the terms and conditions set forth in the Basic Contract DE-EM0000156. This contract is for one full-time equivalent (FTE)- Associate Financial Analyst to serve as support to the EMCBC, Offi
The Illinois Institute of Technology (IIT), in collaboration with Exelon, the Galvin Electricity Initiative (GEI), and other key partners (the team) propose to develop, demonstrate, promote, and commercialize a system and supporting technologie
The Perfect Prototype for the Illinois Institute of Technology
Recovery Act: Energy Distribution: Energy Efficiency & Conservation Block Grant Program
Energy Distribution: To Implement distributed energy resource technologies that significantly increasy energy efficiency
PA will enhance its energy assurance plan through amendments and additions to the existing energy emergency plans.  The existing plans, including Standard Operating Procedures, Emergency Operations Plan and the Emergency Support Function #12 an
The purpose of this award is to strengthen and expand state and local government energy assurance planning and resiliency efforts by incorporating response actions for new energy portfolios and Smart Grid applications and build in-house state a
The Missouri Department of Natural Resources (MDNR) will use the Recovery Act funding to strengthen and expand state and local government energy assurance planning and resiliency efforts by incorporating response actions for new energy portfoli
Ketchikan Gateway Borough, Ketchikan International Airport, Siding Replacement Project
Energy Efficiency and Conservation Block Grant Program - Formula Grant
To Fund an Energy Efficiency and conservation strategy
Purchase and install LED streetlights in Bethel, Alaska.
The proposed work will provide mechanistic insight and fundamentally advance the three key performance metrics for energy storage: energy density, power delivery, and reversibility.  These goals will be realized through development and study o
ARRA: SISGR: Bimetallic Electrochemical Displacement Materials Yielding High Energy, High Power and Improved Reversibility
Energy Efficiency And Conservation Block Grant (EECBG) Improve energy efficiency and reduce energy usage. Fire station energy retrofit(2), Cooling system, automated lighting system(2) HVAC.
Energy Efficiency Community Block Grant that funds 14 projects.  Seven projects address energy efficiency and conservation in government operations, including 1) replacement of two boilers, 2) expansion of one photovoltaic system, 3) virtualiza
Energy efficiency improvements to public facilities These projects are estimated to save 16492 million source BTU's and 1149 metric tons CO2e. Investment in energy efficiency in commercial faclities including providing audits to identify potent
Greeley Energy Conservation and Community Improvement Program
Centennial's primary goals associated with the EECBG grant are to: 1) Reduce the City's carbon footprint by 1,000 metric tons in three years; and 2) Distribute the City's EECBG funded initiatives amongst projects that directly serve the Public,
Energy Efficiency and Conservation Block Grant - City of Centennial, CO
Energy Efficiency and Conservation Block Grant program for City of Cathedral City
The City will acquire Methane Collection System for the landfill and will renovate the air conditioning in City Plaza
The City of Hampton plans to use EECBG funds primarily for actions that will reduce the City's total energy use and support implementation of the energy efficiency and conservation components of the City's long-range 'Go Green' objectives curre
Energy Efficiency & Conservation Block Grant Program
El paso County received funds to contract with an Energy Services Company (ESCO) to perform energy audits on over 1,656,505 sq. ft. of county owned facilities.  Through this process the County will develop a list of energy conservation measures
The City will use all EECBG grant funds to purchase and install energy efficient light emitting diode streetlight fixtures.
ENERGY MANAGMENT PLAN - The plan will include long-term program planning to address energy and greenhouse gas emission from county operations and will expand to include other initiatives as they develop with other public entities within the cou
City of Abilene Energy Efficiency and Conservation Gant Project.  The City of Abilene will utilize grant funds to imporve facility energy efficiency by replacing or upgrading HVAC equipment, make lighting efficiency upgrades, and improve buildi
Energy Efficiency and Conservation Grant Project
Energy efficiency, conservation and renewable infrastructure.
It is the intent of the City of Port Orange, Florida to utilize the Department of Energy, Energy Efficiency and Conservation Block Grants funds to implement a three prong strategy to produce energy savings.    First, because of the city's geogr
Power, Distribution, and Specialty Transformer Manufacturing
Environmental Sustainability in Coral Springs
EECBG grant to decrease the City's Carbon emissions and increase energy efficiency through retrofits(energy performance contract) and upgrades (Lake Pavilion), use of alternative energy in buildings (Lake Pavilion Solar upgrade), and transporta
To develop and implement projects to improve energy efficiency and reduce energy use and fossil fuel emission in communities.  The City of Beaumont plans to install HVAC control systems in seven of its larget facilities.  The HVAC control syste
Funds awarded from the Energy Efficiency and Conservation Block Grant through the ARRA. The City of Gastonia's Energy Efficiency and Conservation Strategy is focused on reducing energy consumption and costs and improving air quality through the
This grant provides support towards awardees of the National Science  Foundation Graduate Research Fellowship Program.  The funds made  available to Duke University on behalf of these graduate students  provides one semester of stipend and one
This project will enhance the underwater search, rescue and recovery capabilities of the Long Beach Fire Department. It will reduce the risk to public safety divers by doing high hazard underwater operations remotely.  Benefits include swifter
FIRM FIXED PRICE DELIVERY ORDER FOR: - 200 GOOGLE APPS PREMIER EDITION FOR PERIOD 7/1/09-06/30/10 - 1 GOOGLE MAPS API PREMIER FOR PUBLIC FACING WEBSITES, 1M ANNUAL PAGEVIEWS
Primary hyperoxaluria type I (PH1) is an autosomal recessive disease caused by excessive oxalate production by hepatocytes due to peroxisomal alanineglyoxylate aminotransferase (AGT) deficiency, leading to increased conversion of glyoxylate to
HEPATOCYTE - BASED THERAPIES OF PRIMARY HYPEROXALURIA 1
Intellectual Merit The ultimate goal of this research is the generation of a new class of polymer composites, comprised of block copolymers densely grafted to the surfaces of highly exfoliated layered silicate particles. I hypothesize that this
CAREER:  Block Copolymer/Layered Silicate Nanocomposites - Dynamics and Thermodynamics
NON-TECHNICAL DESCRIPTION:  Magnetic ceramic nanoparticles will be studied in this project to explore their interesting physico-chemical properties and their prospective applications in catalysis and gas sensing. Enhanced device performance is
Synthesis and Properties of Magnetic Ceramic Nanoparticles
Characterization of the magnetic distortions in closed-circuit magnetic measurements will be investigated by University of Dayton researchers. These distortions were reported for the first time by us in 2008, and the physics behind the phenomen
Characterization of the Magnetic Distortions in Closed-Circuit Magnetic Measurements
This award is funded by the Division of Materials Research and the Chemistry Division. It supports theoretical research and education on how oligomer/polymer films interact with and emit light. The PI aims to investigate fundamental excitations
Using Circularly Polarized Light to Probe Electronic Excitations in Organic Supremolecular Assemblies
The understanding of many non-equilibrium processes has been enhanced by the use of phase-field modeling methods. The basic idea behind this method is to propose a free energy that is a functional of a continuum or phase-field that distinguishe
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).   This Materials World Network (MWN) team consists of five experimentalists and two theorists from China, Colombia, Japan, Switzerland, and the US
Materials World Network: Novel Physical Phenomena in Unusual Mesoscopic Superconductors
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  This Materials World Network project integrates and maximizes the interrelated, but distinct, areas of expertise of two research groups from the
Materials World Network: The Subtle Balance Between Rigidity and Swelling in Functional Nanoporous Polymers
PRESIDENT & TRUSTEES OF WILLIAMS COLLEGE
The award will be used for an AFM system for use by multiple research groups in multiple departments at Williams College.  There are a number of ongoing research projects that will be enhanced by the acquisition of an AFM; in addition, a number
MRI: Acquisition of an AFM System for Imaging and Characterization of Synthetic Nanostructures and Native Biological Macromolecules.
The present proposal seeks funding to purchase a JEOL JSM-7600F Thermal Field Emission (FE) Scanning Electron Microscope (SEM) (or equivelent) for interdisciplinary Nanotechnology research and teaching at Wayne State University.  This proposed
ACQUISITION OF AN ANALYTICAL FIELD EMISSION SCANNING MICROSCOPE FOR RESEARCH AND TEACHING
To provide support for projects/initiatives funded under The American Recovery and Reinvestment Act of 2009 (ARRA). This project will provide economic stimulus to the nation while furthering the NSF mission to promote the progress of science; a
PENN-UPR Partnership for Research & Education in Materials
FRG:  Collaborative Research:  Stochastics and Dynamics:  Asymptotic Problems
The principal investigators propose to undertake a systematic development of a theory for elliptic partial differential equations on a compact manifold with singularities of edge type. The core of the project is a precise description of boundar
Collaborative Research:Elliptic Partial Differential Equations on Singular Manifolds and Applications in Complex Geometry
This project aims to study a class of dynamical systems on the Wasserstein space of probability measures corresponding to some fundamental systems of partial differential equations in fluid and quantum mechanics.  A nice feature of the Wasserst
Calculus of Variations and Hamilton-Jacobi Equations in the Wasserstein Space
This project is in the field of asymptotic geometric analysis, which deals with high-dimensional phenomena in convex geometry and functional analysis, and more specifically in applications of probability theory in this field. The project has tw
Probabilistic aspects of asymptotic geometric analysis
Supported by the proposer's previous NSF grant, a total of 17 papers were published, accepted, or submitted. Among these papers, four conjectures were proved (some jointly with other people) and one proposed in the area of spectral theory from
On the Geometry of Calabi-Yau Moduli and Kahler-Einstein Manifolds
This is an RUI proposal focused on the study of graphs embedded in 3-space. This area of topology was developed in the early 1980’s in order to study DNA recombination as well as to aid in the analysis of molecular symmetries. Since then it h
Topological symmetries and intrinsic properties of graphs embedded in 3-space.
The proposed research is divided into five parts: (1) Investigate Hausdorff dimension of minimal sets of known counterexamples to the Modified Seifert Conjecture; (2) Investigate periodic orbits and periodic points in neighborhoods of planar ad
Department of Mathematics and Statistics
In this project, the investigator develops computational methods for Bayesian optimal sequential design for the estimation of random functions. Intellectual Merit: Random function estimation, either in the context of Bayesian nonparametric regr
Bayesian Optimal Sequential Design for Random Function Estimation
This project will allow the PI to continue to establish fundamental theories for various nonautonomous and random differential, paying special attention to the effects of the time/space dependence and randomness on the dynamics of the underlyin
Dynamical Aspects in Nonautonomous and Random Differential Equations and Applications
The investigator works on the topology of algebraic maps, with applications to algebraic cycles. The study of the relations between the topology of the domain and target of a map is interesting and has broad applications in the fields of geomet
ARRA: The Topology and Hodge Theory of Algebraic Maps
The focus of this proposal is the development of a comprehensive theory to analyze (inverse) scattering problems with waves in random media generated by (random) ambient noise sources. In particular, the investigators are interested in the anal
Collaborative Research:  Stochastic and Multiscale analysis of Ambient-Noise Generated Scattered Waves and Imaging
Computational Methods for Studying Heterogeneous Pulse-Coupled Network Dynamics
Our research is directed towards detecting osteoporosis, a major public health threat affecting more than 44 million Americans. Both treatment and prevention of the disease rely on the best assessment possible of the condition of the patient's
Collaborative Research: Novel mathematical methods for retrieving mechanical properties and microstructural information of cancellous bones
RESEARCH SUPPORT for  Root Number of Abelian Varieties and Related representation-Theoretic Questions
Root Number of Abelian Varieties and Related representation-Theoretic Questions
Recovery act funding for project phases three and four
Optimally Controlled Flexible Fuel Powertrain System
Energy upgrades to five (5) municipal facilities and buildings.
Lakewood Township Energy Upgrade Program
Evaluation panel member tasked with reviewing applications received in response to a solicitation for grant application (SGA).  Grants awarded as a result of the SGA will be related to ARRA initiatives and are funded with ARRA funding.
Computer Servers and Storage for Dept of Labor
Occupational Safety and Health Administration
supplies- munsell color charts, sand grading chart, torvane shear device, pocket penetrometer, penetrometer adapter foot, tropical color chart
THE FUNDING IS INTENDED TO CORRECT THE FOLLOWING FACILITY DEFICIENCIES IDENTIFIED AS GREEN INITIATIVE PROJECTS: #T2021 - ACADEMY (CENTER) LANDSCAPING AND #T2022 - OUTDOOR RECREATION AREA PAVILION PROJECT.
THE FUNDING IS INTENDED TO PROVIDE ADDITIONAL AUTO AND CNST CURRICULUM AS WELL AS CTST GREEN INTIATIVE PROJECTS: T6031, T6032, T6033. A RE-DIRECTION WAS COMPLETED TO TRANSFER FUNDING FROM EQU AND OPS TO CTST TO COVER ADDITIONAL WINDOW INSULATIO
Purpose:  To support ETA's Office of Workforce System Support Governance Team, which is responsible for reviewing Workforce Investment Act waives and State Plan, recommending approval, and preparing response to states. TATC supports the Governa
The funding is intended to correct the following facility deficiencies identified as Green Initiative projects: Solar Energy System Installation.  These funds are available for additional Career Technical Skills Training opportunities to the st
Project# T3061;3062 & 3063 Solar Energy Conservation
projects.  These funds will be available for the Inland Empire Job Corps Center to utilize the services of students enrolled in Job Corps' Career Technical Skills Training (CTST).  NOTE: $1356.65 (Mod #45) redirected to Landscape/Softscape, H
The contractor shall provide Techinal Assistance to 50 additional grantee who received grants through funding from the American Recovery and Reinvestment Act (ARRA). As a result the contractor will (1) provide on-site technical assistance to as
With additional funding through ARRA, Partners expands its work as the Organizational Capacity Building YouthBuild Technical Assistance provider to more than 200 DOL-funded YouthBuild programs.  Partners works closely with grantees ranging from
The objective of this project is to replace one-hundred and seventy three (173) one rack unit (1RU) servers that make up the Job Corps Citrix server farm with seventy (70) 4RU servers.  A RU is a unit of measure used to describe the height of e
Construction of a New Dining Facility at Columbia Basin Civilian Conservation Center
Columbia Basin Civilian Conservation Center
Review wage data submitted in response to Davis-Bacon (DB) wage rate data gathering effort.  Make clarification telephone calls in accordance with DB standard survey procedures. Transfer peak week wage data from certified payrolls onto WD10 for
Project# 1091 - Campus Grounds Restoration Replacement of old Sod with Turf tall Fescue  Growth retardant/drought restatant.
Deficiency ID # 66177 - Carpets were damaged by a storm This deficiency is being re-evaluated by the DOL Architectural and Engineering firm of PB Dewberry for re-assignment to a new project.
MC NEELY PIGOTT & FOX PUBLIC RELATIONS, LLC
Outreach initiative in the area of purchased media spot buys. The contractor is responsible for purchasing media in areas such as television, print and/or Web outlets for 1)raising awareness among employers and influencers about the program's
Recovery Act - Energy Efficiency & Conservation Block Grant Program. Production of renewable energy and reduction of emissions.
City of Alamogordo Energy Efficiency Initiative
Place new windows and boiler in the courthouse and put new heating and cooling system at the health department.
Recovery Act - Energy Efficiency & Conservation Block Grant Program
Recovery act-Energy Efficiency & onservation Block Grant Program
Cass County is working on a Lighting Retrofit project for our historical courthouse building which is on the National Historical Register.  In moving ahead with the energy efficient lighting retrofit within the courthouse, it provided the oppor
Recovery - Energy Efficiency and Conservation Block Grant Program  Iron County Courthouse Energy Retrofit.  To redue energy costs and GHG emissions by replacing portions of outdated mechanical systems in the county's courthouse.  The primary go
Iron County Courthouse Energy Efficiency Retrofit Project
Energy Efficiency upgrades to the Public Safety Building
The overall accomplishment desired is to create energy efficiency in the Littleton community and  City of Littleton. It is anticipated that the City of Littleton will approach this by first, use the ARRA funds to retro-fit resdientail homes wit
Replacement of existing non-thermally broken aluminum windows with high effeciency metal-clad wood windows with thermal glazing, argon gas and low -E
Energy  Effecient Reto fitting to Bage county Courthouse through replacement of windows in the emergency operations center
TAS: 89-0227: TAS RECOVERY ACT?CENTER ON MATERIALS FOR ENERGY EFFICIENCY APPLICATIONS?EFRC; DOE Recovery Act Project Identification Code: 2005000 As defined in the Award Description Field. Some highlights are: (1) We have improved the performan
TAS: 89-0227: TAS RECOVERY ACT?CENTER ON MATERIALS FOR ENERGY EFFICIENCY APPLICATIONS?EFRC; DOE Recovery Act Project Identification Code: 2005000
The City of Waco's project is to replace City of Waco owned HID street lighting  with LED energy efficient lighting.  The proposal is to replace 2,226 older lighting fixtures. Three projects have been cancelled: 1)upgrade to a new energy effici
EECBG awarded to the City of Harrisburg, Pennsylvania for the development of an Energy Efficiency & Conservation Strategy and its implementation in key City of Harrisburg buildings
Development of Energy Efficiency and Conservation Strategy, costs associated with energy reduction, and projects approved by DOE
This activity can be separated into two separate projects.  The first is the installation of variable frequency drives (VFD) for the facility's four (4) aeration blowers and two (2) return and waste sludge pumps.  The purpose of this project is
Energy Efficiency & Conservation Block Grant for Norman Wastewater Pollution Control Facility
EECBG DEVELOPMENT AND IMPLEMENTATION OF A COMPREHENSIVE ENERGY STRATEGY
The City of Costa Mesa's strategy for reducing electrical consumption and green house gas emissions as well as producing renewable electrical energy focuses on two EECBG project activities: 1) the ?Energy Efficiency retrofit Program and 2) Rene
Costa Mesa Energy Efficiency retrofit and Renewable Energy program
The Fairbanks North Star Borough (FNSB) will establish and maintain an on-going program to educate the public on the health impact of wood smoke, investigate ways to assist the public with replacement or removal of wood stoves through education
Fairbanks North Star Borough Energy Efficiency Education and Public Outreach
City of Folsom's EECS was approved and grant awarded on 3/24/10.  The City is in the process of implementing a photovoltaic system at the Folsom Sports Complex facility.  The original EECS planned two other performance activities; 1)participati
Award 6 EECBG activities: retrofits,financial incentive program, renewable energy demonstration, technical assistance, EECS, County Energy Policy
Energy Efficiency Conservation Block Grant (EECBG) from the Department of Energy. Funds will be used for a variety of projects including grants/loans to homeowners for energy efficiency upgrades, upgrades to City streetlights, how-to retrofit c
Energy and Efficiency Conservation Strategy
The total award will cover two activities.  The first activity is an energy reduction project at the Carl Perkins Civic and Convention Center that involves replacement of variable volume boxes along with replacement of lighting in the lobby, au
The Municipality will provide assistance to low income families for the installation of solar water heaters, replace lighting fixtures, and the replacement of inefficient appliances in housing units.  The goals of the program are to increase en
Incentive to homeowners to perform Energy Efficiency Retrofits / Energy Efficiency and Conservation Block Grant Program (EECBG)
Energy Efficient Retrofit Conservation Block Grant Program
Hamilton County will undertake four energy efficiency initiatives.  (1) The energy audit of County buildings will provide baseline data in order to set priorities for future maintenance, formulate measurable energy efficiency goals, and measure
Energy Efficiency and Conservation Block Grant: The City of Peoria will use its distribution to create a conservation strategy as well as retrofit 11 City facilities to be more energy efficient.
Coconino County Energy Conservation and Green Workforce Development Program.
Develop energy efficiency and conservation strategy by traffic modeling and synchronizing 58 traffic signal intersections.
Lakewood Energy Efficiency & Conservation
Tulare Solar Initiative to install solar power plant.  Technical consultant for Climate Action Plan.
The purpose of Middletown's EECBG award is to Reduce the community's carbon footprint, and create and retain jobs. The expected outcomes are(1) Complete an Energy Efficiency Conservation Strategy and Energy Plan, (2)Create an Energy Manager pos
Various locations throughout the Township
Energy efficiency retrofits for municipal facilities and establishment of energy efficiency improvement revolving loan fund.  The city will utilize its EECBG formula funding to retrofit and improve the energy efficiency of a number of its munic
Plasma-surface interactions (PSI) pose an immense scientific hurdle in magnetic confinement fusion and our present understanding of PSI in confinement environments is highly inadequate. This PSI Science Center will focus on state-of-the-art PSI
PSI Plasma Center: Bridging the PSI Knowledge Gaps - A Multiscale Approach
Energy Efficiency and Conservation Block Grant - Hamilton County, Indiana
Grant funding will facilitate installation of approximately 21,370 square feet of photovoltaic panels (1290 total panels) on the south and west facing roofs of Town Hall and Municipal Services Buildings, plus a small shade structure supporting
Tippecanoe County will undertake 3 projects: Tippecanoe Battlefield Museum Retrofit; Lighting and Energy Audit for County Buildings; Advanced transportation Management System.
Installation of a solar PV system and monitoring system, new Municipal Bldg windows, cooling units and interior lighting as well as new Health Dept interior lighting.
The City of Warren's proposed energy efficiency and conservation strategy is to reduce energy use in the building sector by improving energy efficiency and conservation at city facilities, while also developing a new and sustainable workforce f
EECBG energy efficiency upgrades and education
The City of Evanston?s EECBG Energy Efficiency and Conservation Strategy (EECS) focuses on six EECBG project activities: 1) Energy Efficiency Retrofits; 2) Residential and Commercial Building Energy Audits; 3) Development and Implementation of
City of Minnetonka Recovery Act - Energy Efficiency and Conservation Block Grant
On June 7, 2010, the City of St. Cloud grouped and awarded the contract bids as follows:  Project A, City Hall HVAC, occupancy sensors for the Paramount Theatre, compressed air system for the Water Treatment Facitlity and installing a co-genera
Energy efficiency upgrades to City Hall HVAC Systen and Window improvements, Water Treatment Plant high pressure air system, Central Services Facility cogeneration, Paramount Theatre HVAC and occupancy Sendor Upgrade and LED Street Light retrof
Street light energy conservation program to replace approximately 1300 metal halide fixtures with more efficient LED luminaires
This project is designed to install facility energy saving devices to public buildings including occupancy sensors, automatic flush valves, etc. Additionally, a high intensity compactor will be installed at a local landfill site to reduce the n
The EECBG funds will be used to help offset the total project cost of replacing the Beachmont School roof and HVAC units.  The Beachmont project is one part of a 15-year energy services contract between Revere and Ameresco, Inc.  The remainder
Beachmont School-Energy Saving Performance Contract Project
Amendment #1:  New Data Center (Energy efficiency retrofits) and Visitor Center Upgrades (Energy efficiency retrofits) Amendment #3:  Municipal Facilities Retrofits (Energy efficient upgrades to municipally owned buildings)  Amendment #4/6:  Mu
New Data Center/Visitor Center/Municipal Fac. Retrofits/Amendment
Energy Efficiency and Conservation Block Grant-Fayetteville, NC
Forsyth County will invest their EECBG funding in county building retrofits for energy efficiency improvements. Funding will be used to replace 25-30 year old HVAC units in buildings 15,000 square feet or larger with energy efficient units. Ano
Forsyth County Building Retrofits for Energy Efficiency
Activity one the City of North Port will partner with Sarasota County in a joint Community Energy Retrofit Program.  Activity two, the City will take the lead role in responding to the necessity of conserving energy and reducing greenhouse gas
City-wide Comprehensive Energy Conservation and Efficiency Strategic Plan and Community Energy Retrofits Incentive Program
Decision tools to inform national scale expansion for the electric power grid, and its regional operation and markets, must be dramatically enhanced to treat large-scale uncertainty in scenarios of new technology adoption, increasing impact of
TAS: :89 0227: :TAS Recovery Act - OPTIMIZATION AND CONTROL OF ELECTRIC POWER SYSTEMS
Energy Efficency and Conservation Block Grant
Wright County has implemented  a series of retrofits to promote Energy Efficiency and Conservation.  Activities include HVAC retrofits and upgrades, boiler replacements, and lighting retrofits.
Building Retrofits to Improve Energy Efficiency and Conservation
Energy Efficiency and Conservation Stratey Development & Street Lighting Retrofit Audit
Energy Efficiency and Renewable Energy Conservation Block Grant
EECBG activities include nine project activities intended to decrease the City of Fargo's energy consumption and create/retain jobs.
The City's strategy is to address energy efficiency and renewables technology opportunities in our municipal buildings.  The principle objectives we applied to our planning for the ECBG funds are to fully utilize the funds by retrofitting sever
Multiple energy efficiency projects funded by ARRA EECBG funds.
This project develops synthetic methodologies for, and the fundamental characterization of, cyclic polymer topologies.  Preliminary investigations will also probe the utility of this relatively unexplored macromolecular family for a range of ma
This CAREER Award funds a combined research and education program that will explore methods to control quantum coherence and entanglement of quantum systems in complex environments. The research program will study the fundamental properties of
CAREER: Controlling Coherence and Correlations in Solid-state Quantum Systems
The proposed work will contribute to emerging technology solutions in fields such as photovoltaics, non-linear optics and membranes. It specifically takes aim at the production of semiconducting materials which can be used for next generation s
CAREER: Directed Self-Assembly of Block Copolymers by High Magnetic Fields
This is a project that will fund materials science trainees, especially graduate students, to determine the properties of a new and intriguing class of organic materials that have surprising capability to transmit electron currents in semicondu
Pyromellitic Diimide (PyDI)-Based Molecular and Polymeric Electron-Transporting Semiconductors
Two-dimensional (2D) electron systems, systems where the motion of the electrons is confined to a plane, i.e. 2D, are not only relevant to advanced microelectronic and optoelectronic devices, but also important platforms in the study of electro
Elucidating the Anomalous Metallic State in Stongly Correlated 2D Fermions with Density of States
Technical Abstract  This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). Multiferroic tunnel junction refers to a ferromagnetic tunnel junction using a ferroelectric insulator barrier. Theoretical ca
Technical Abstract :We request funds for a Nanomill, a novel ultra-low-energy concentrated ion beam system for preparing highest-quality specimens for transmission electron microscopy. Designed to perform the final polishing step on specimens t
MRI: Acquisition of a Nanomill for Preparing Highest-Quality TEM Specimens
FRG: Collaborative Research: generalized geometries in string theory
'The inner model program attempts to associate to each large cardinal hypothesis H a canonical minimal universe of sets in which H is true. The stronger H is, the larger this minimal universe will be. Some of our deepest understanding of large
The Cauchy-Riemann complex is a system of partial differential equations describing the behavior of holomorphic functions, which are fundamental objects of study in many areas of pure and applied mathematics.  The PI will investigate the proper
The Caunchy-Riemann Complex on Non-Smooth Domains.
This project investigates special fibres of good integral models of Shimura varieties of abelian type. The special fibres are smooth, quasi-projective varieties over finite fields which have a rich structure due to their expected (conjectured)
ARRA: Points of Integral Models of Shimura Varieties of Hodege Type and the Tate Langlands-Rapoport Conjectures
This project funds the study of interpolation problems for bounded (more specifically, bounded by one in modulus) analytic functions on the unit disk, the area of mathematics which has traditional connections with engineering and control theory
PARSONS INFRASTRUCTURE & TECHNOLOGY GROUP INC.
This project involves construction of the Runway 31 MALSR located at the Northeast Georgia Regional Airport located in Winder, Georgia. This project has been awarded under Contract DTFA0102C0016, Modification 725. The Modification is in the amo
Analysis, Design, Development services for the Recovery Act Database System (RADS).  Reporting and Tracking support for the FHWA Chief Financial Officer.   Note regarding Officers Compensation Table:  The amounts are annual numbers for the cale
Scoping, preliminary design and final design work, plans and specifications for the replacement of 6 bridges, Tajique-Torreon Loop Bridges
CONSTRUCTION OF CA PRA REDW 102(1), ALDER CAMP ROAD
FORT PECK ASSINIBOINE & SIOUX TRIBES INC
GTSR Rehabilitation Big Bend to Logan Pass, Phase VIII.  The project is rehabilitation of approximately 2.84 miles of Roadway in Glacier National Park.  Major items of work include surveying, quality control, removals, 2100cy of excavation, 580
'The NSF Mathematics Specialist Partnership Institute will be offered to 50 outstanding middle school teachers. Each teacher will: participate in a 66 day Institute offered over three consecutive summers; complete a total of 33 graduate credits
MSP Institute: Mathematics Specialists In Middle School
will develop a close partnership between the lead institution California State University, Los Angeles (CSULA) and a core partner, the Montebello Unified School District (MUSD). Through mutual engagement in Professional Learning Communities, de
Through this planning grant, steps are being taken to develop the framework for a Master Teaching Fellows program. This project builds on an existing Noyce scholarship program in the Cleveland region. It is anticipated that the Master Teaching
The Memphis Mathematics and Science Teacher Induction Fellowship program represents a partnership among the University of Memphis, the Memphis City Schools, and the non-profit Partners in Public Education. The partners are working together to r
WKU Science and Mathmatics Alliance for Recruitment and Retention of Teachers.
WKU Science and mathmatics alliance for recruitment and retention of teachers.
Project Summary A total of 28 physics and mathematics secondary teachers will be trained, who will transform the way these disciplines are taught to high school students. Pre-service teachers will practice hands-on, inquiry-based teaching under
ARRA - Nurse Faculty Loan Program.  The Nurse Faculty Loan Program provides funds to eligible schools of nursing that offer advanced education nursing programs to prepare graduates to serve as faculty in a school of nursing.
ARRA - Nurse Faculty Loan Program (NFLP) for Aspiring Nurse Faculty Enrolled in the Master's Program
The NFLP will provide financial aid for full and part-time students in the Masters of Nursing and Doctor of Nursing Practice (DNP) programs who complete the nursing education.
Nurse Faculty Loan Program (NFLP) 09-10 (ARRA funds)
Establishmen of a new high pressure scale that will be used to make accurate determination of pressure at high temperature in the externally heated and laser heated diamond anvil cell.
The State University of New York - New Paltz (SUNY New Paltz) and the New York City Department of Environmental Protection (DEP) will sponsor an eight week summer research experience for 12 highly motivated undergraduate students conducting a c
ARRA: Comprehensive Approach to Watershed Characterization Focusing on the Source of NYC Water
Although large-scale convection in the Earth?s mantle ultimately controls tectonic deformation at the Earth's surface, the link between deep mantle flow and plate tectonics remains poorly understood. This is because patterns of mantle flow are
CSEDI Collaborative Research: Influence of Grain-Size Evolution on Global and Regional Mantle Flow and Upper Mantle Seismic Structure
Research proposes to use Holocene lake sediment records from British Columbia (BC) to reconstruct the spatial and temporal patterns of drought/pluvial cycles along the cordillera of western North America to help identify the underlying causes o
Collaborative Research: Spatial and Temporal Patterns of Drought in Western North America during the Holocene
This grant will support the development of calibrated, highly-resolved, and absolute-dated stable isotopic and trace-metal time series from multiple speleothems preserved in multiple cave systems along a N-S transect from East Tennessee, throug
Hydrologic responses to earthquakes, such as increases in stream flow or changes in the water level in wells, are not uncommon. Such hydrologic responses are important because they provide unique insight into the coupling of hydrologic and tect
Origin of Hyrdologic Responses to Earthquakes: Constraints from the Response of Alum Rock Springs to the 2007 Alum Rock Earthquake
Acquisition of a Dual Beam FIB/SEM system for the Carnegie Institution of Washington, which will be used for sample characterization, micro/nano-fabrication, and sample preparation
MRI:  Acquisition of a Dual Beam FIB/SEM
MRI: Acquisition of an X Ray Diffractometer for Research and Training Applications in a Multidisciplinary Setting
This award will provide funding to acquire an infrared microscope and Fourier Transform infrared spectrometer (FTIR). The instruments will be used for measuring apatite in igneous and metamorphic rocks of various origins. Data will be develope
Acquisition of an FTIR for the Nature Research Center, North Carolina Museum of Natural Sciences
North Carolina Museum of Natural Sciences
MUSEUM OF THE EARTH AT THE PALEONTOLOGICAL RESEARCH INSTITUTION
The Paleontological Research Institution (PRI) will purchase a benchtop scanning electron microscope for use in research and education. PRI has one of the most significant research collections of fossils in North America, including an outstandi
Acquisition of a New Generation Benchtop SEM for Earth Systems Research, K-16 Education, and Public Outreach
The objective of this proposal is to quantify the relative importance of surface area and quality factor on the sensitivity of detecting small molecules. While high quality (Q) factor resonant optical biosensors require fewer target molecules t
Goali:  Role of Surface Area and Quality Factor on Small Molecule Detection Sensitivity
The focus of this research is the design of algorithms and real-time system implementations for the task of source localization and separation using miniature sensor arrays. The dimensions of the arrays are much smaller than the wavelength of t
ARRA: CAREER:  Spatial Sensing for Design of Miniature Sensor Array Microsystems
Clog Free Nozzle-based Ejector Array Using Thin Liquid Film Valves
The objective of this research is to investigate phase-coherent, fiber optic multiple access communications for efficient, flexible, and secure local access networks. The proposed coherent diversity receiver cancels multiple access interference
A Key Enabling Technology for Optical Networks
Start Date is 1/1/2010 Summary of the proposed work This project brings together a multidisciplinary team with complementary expertise in biological vision (Connor), computer vision (Bajcsy, Vidal), dynamical systems (Vidal), robotics (Bajcsy),
CDI-Type I: Collaborative Research: A Bio-Inspired Approach to Recognition of Human Movements and Movement Styles
ECCS/PCAN/EAGER: Biologically Inspired Resource Harvesting in Mobile Wireless Networks  -  This research will provide techniques to harvest and manage two of the most important resources required by a wireless mobile device: energy and computin
ECCS/PCAN/EAGER: Biologically Inspired Resource Harvesting in Mobile Wireless Networks
The overall purpose of Title I, Part A ARRA funds for eligible children attending private schools that are allowable under Title I and consistent with ARRA principals are providing professional development to teachers in Title I targeted assist
The Weatherization Assistance Program’s mission is to enhance the well-being of low-income residents, particularly those persons who are most vulnerable such as the elderly, the handicapped, and children, through the installation of energy ef
Weatherization Assistance for Low Income Persons. American Recovery and Reinvestment Act (ARRA)
NATURAL RESOURCES, LOUISIANA DEPARTMENT OF
Louisiana's State Energy Plan consists of seven programs designed to help increase energy efficiency throughout the state.  1) 'Lead by Example' - the Lead by Example program will provide funding for enegy efficiency retrofits of higher educati
Recovery Act: Establish environmental efficiency infrastructure for Montgomery, Alabama.
Allegheny County will utilize its EECBG (Energy Efficiency Conservation Block Grant) funding to invest in eligible energy efficiency improvement activities that will result in substantial reductions in energy usage and costs; deliver immediate
2004350-EE Conservation Block Grant Program
Yurok Tribe Energy Efficiency Improvements
The purpose of this project is to install a solar photovoltaic system on the Tribal Health Clinic.
Santa Ynez Chumash Energy Efficiency and Conservation Block Grant Program
Energy Efficient and Conservation Block Grant
Recovery Act Energy Efficiency and Conservation Block Grant
TAS::89 0331::TAS RecoveryRecovery Act EECBG
Energy Efficient Lighting Upgrades for Dublin Municipal Buildings
2004350-EE Conservation Block Grant Program for energy retrofit of community center	+
Recovery Act: Tonkawa Tribal Energy Efficiency and Conservation Project
We will  use the EECBG funds to conduct residential audits and provide energy efficient retrofits to the homes on our Reservation.  We will also provide consumer education in a workshop setting to any interested tribal members in the area.  Onc
'The proposed research and development efforts seek to produce low emission burner technology capable of operating on natural gas as well as crude glycerin and/or fatty acids generated in biodiesel plants. The burner system will be tested for u
Advanced Materials RD&D in Support of EERE Needs to Advance Clean Energy Technologies and Energy-Intensive Process R&D
Award to be divided between two projects. The firest project (expending $100,000) is the replacement of HID street lights with LED fixtures. The second project (expending $65,000) is the retrofit of existing fluorescent lamps to T-8 and electro
RECOVERY ACT RESEARCH SUPPORT TO STUDY Algebraic Dynamics over Global Fields
Algebraic Dynamics over Global Fields:  Geometric and Analytic Methods
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).   The principal investigators propose to undertake a systematic development of a theory for elliptic partial differential equations on a compact m
RUI: Collaborative Research: Elliptic Partial Differential Equations on Singular Manifolds and Applications in Complex Geometry
This project concerns topics surrounding two key conjectures that have arisen in recent years in the field of number-theoretic dynamics. The first conjecture, stated by Morton and Silverman in 1994, predicts that there is some uniform upper bou
RUI: Boundedness questions in arithmetic dynamics
V.Tarasov intends to study various types of Bethe algebras, that include the Bethe algebras of the XXX-type models, as well as the Bethe subalgebras of the group algebra of the symmetric group, the affine Weyl group, the degenerate affine Hecke
Bethe ansatz, Hecke algebras, and asymptotics
Classical unsolved problems often serve as the genesis for the formulation of a rich and unified mathematical fabric.  Diophantus of Alexandria first sought solutions to algebraic equations in integers almost two thousand years ago.  Today, mat
Quaternion Algebras, Shimura Curves, and Modular Forms: Algorithms and Arithmetic
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  In this work, the investigator develops a new global optimization technique, which is primarily motivated by applications in drug discovery.  Alt
In ``3-manifolds as viewed from the curve complex'' (\cite{He1}), J. Hempel demonstrated the usefulness of the curve complex as a tool in the study of 3-manifolds.  His investigation introduced concepts and methods from geometric group theory i
This project aims at studying the geometric properties of Schramm-Loewner evolution (SLE) introduced by Oded Schramm. SLE describes conformal invariant random fractal curves in plane domains, which are the scaling limits of many interesting two
Commutation relations for SLE in multiply connected domains and the coupling technique
The proposed research has two main parts. The first part concerns producing new smooth and symplectic closed four-manifolds so as to address a variety of problems that range from constructing non-diffeomorphic copies of standard four-manifolds
Geometry and topology of smooth four-manifolds
Dynamics of Gaseous Stars and Hydrodynamic Limits for Boltzmann Equations
This project deals with the development, analysis and implementation of novel techniques for the solution of large, sparse linear systems of equations of saddle point type.
We propose to exploit advances in theory and 3D simulation to investigate the prediction and control of two-phase microstructures. We will focus on solid/liquid and solid/solid diffusional phase transitions in pure materials. Diffusional phase
Collaborative Research:  Computational and Theoretical Approaches for the Morphological Control of Material Microstructures
Early stimulation and nurturing of mathematical interest of undergraduate students is a key in improving the overall quality of undergraduate mathematics program, increasing the number of students in successful pursuit of advanced degrees, and
PRISM:  UCI Interdisciplinary Computational and Applied Mathematics Program
No order number cross references Mod #31
Center awarded funds to correct deficiencies around Turner Job Corps Center.  Projects to be completed with award include: replace roof on a building, replace downspouts on building, repair deteriorated exterior walls of building, replace elect
Awarded on Modification # 28:  Landscape Project # T1031 - Beautifying the Center using native plantings, water harvesting and composting.            Landscape Storage Building # T1032 - Construction of a 20' x 24' garage used to store FM vocat
For San Jose Job Corps Center: Purchase curriculum items and equipment for new  green tar requirements in Ed Services CTT for Auto and Construction vocations.
The funding is intended to correct the following facility deficiencies identified as Green Initiative projects:   Tx active cement; exterior light pollution reduction; water sense fixtures; programmable thermostats; exterior stucco; recreation
Provide design and construction management services relative to ARRA funded projects, including Scope of Work preparation, project budgeting and scheduling, cost estimating, A/E,GC procurement, contract negotiation, design review, construction
THE FUNDING IS INTENDED TO HELP COMPLETE CTST GREEN INITIATIVE PROJECTS: #T6021, T6022, T6023, T6024 AND T6025.
These funds were provided to the Earle C. Clements Job Corps Center. The funding is intended to correct the following facility deficiencies: Roof Deficiencies, Exterior Wall Deficiencies, Exit Door Deficiencies, Window Deficiencies, Interior Fi
Procure and deliver 11,028 personal computers and monitors
Replace outside lighting fixtures and electrical ballasts, specifically for: 1) the walkway leading from the cafeteria to the academics building; and 2)the lighting on the street from the main gate to the gym. This funding relates to rehab defi
Door, window, frames and recreation space - Deficiency #69593, 69596, 69602, 69703
2009 Statewide Drainage Improvements Contract 3
Development for but not limited to deactivating and decommissioning (D&D) of Building 701 at Brookhaven National Laboratory (BNL)
to reflect the affects of the America Recovery and Reinvestment Act (ARRA) on the project documentation. Support shall include the revision of DOE approved documentation including documents such as: Project Execution Plan; Risk Management; Pre
SRS D&D, Soil & Groundwater Activities Site-wide Recovery Act Project
Program Management (Stimulus Projects). The task was awarded under an existing Indefinite Delivery Indefinite Quantity contract. It provides resources and services necessary to perform program management for the proposed Air Route Traffic Contr
power cable infrastructure replacement projects at Los Angeles, CA and Electric Line Distribution (ELD) Power Cable Replacement
Construction Contract for Paking Lot Improvements and Modifications at the Fort Worth Air Route Traffic Control Center
Provide non-personal, professional engineering support servicses for FHWA's Utah Division for oversight of 20 ARRA projects in Utah.
Provide construction inspection services for CA PRA PWR Lame
Provide Construction Inspection Services for the ND PRA THRO 10(3), North Unit Slide Repair project
A/E Resource surveys and reports for wetlands, ordinary high water, biological resources,  cultural resources; Biological Assessment, biological assessment and evaluation tasks and creating Aesthetic Treatment Visualizations  Deliverables inclu
The Purpose of the project is to replace eleven existing stream structures on Esmond, Hawley and Buck Creeks.  Most of the culverts will require fish passage design.  The project is located in Lane and Douglas Counties, westerly of Cottage Grov
The Western Federal Lands Highway Division (WFLHD) of the Federal Highway Administration is preparing to proceed with plans for a geotechnical foundation exploration for three new bridges on the Salmon River, west of North Fork, Idaho.Provide a
ARRA - TRANS-NSF RECOVERY ACT RESEARCH SUPPORT Robert Noyce Teacher Academy at College of Staten Island  Twenty nine mathematics and science pre-service teachers for grades 7 - 12 are receiving Noyce scholarships awarded by the College of State
Robert Noyce Teacher Academy at College of Staten Island
The University of Kansas Noyce Phase II Scholarship and Stipend Program (Phase II Noyce) is a collaboration between the College of Liberal Arts and Sciences, the School of Education and high needs school districts to increase the number of tale
The University of Kansas Noyce Phase II Scholarship & Stipend Program
The Cal Teach at Berkeley Robert Noyce Teacher Scholarship Program is supporting undergraduate students in mathematics, science and engineering toward their disciplinary degrees and K-12 teaching credentials, with a focus on teaching in urban s
Cal Teach at Berkeley: Robert Noyce Teacher Scholarship Program
MIA Great Miami Bikeway Connection, South
The goal and objective for the use of these funds are to award our nursing students with low cost loans.  In doing so, upon graduation our students will be able to practice in underserved areas as well as become faculty members.
Provide Hydrological Instrumentation: self contained gas purge systems for use with non-submersible transducers with installation kits
Instrument Manufacturing for Measuring and Testing Electricity and Electrical Signals
GPCOG Brownfields Assessment program for hazardous substances sites.
To conduct community-wide assessments at potential Brownfield sites contaminated with hazardous substances.
Brownfields Hazardous Substance Assessment Grant
Revolving Loan Fund Program for Niagara County
This award provides American Recovery and Reinvestment Act funds to the City of Springfield Missouri, to be used to conduct community-wide assessments at potential brownfield sites contaminated with petroleum.  Activities will include conductin
ARRA Springfield Brownfields Petroleum Assessment
American Recovery and Reinvestment Act Funding, Kansas City Brownfields Supplemental Revolving Loan Fund.  This award provides American Recovery and Reinvestment Act funds to the City of Kansas City, Missouri, to utilize funding to provide a Re
American Recovery and Reinvestment Act Funding, Kansas City Brownfields Supplemental Revolving Loan Fund.
Department of City Plannnig & Development
This award provides American Recovery and Reinvestment Act (ARRA) funds to the City of Sioux City, Iowa, to provide a Revolving Loan Fund (RLF) for the community to assist funding cleanup planning and remediation activities. The purpose of thes
ARRA Sioux City IA Brownfields Supplemental RLF
Provides stimulus funding to UT DEQ to be used to conduct community-wide assessments at potential brownfields sites contaminated with petroleum. Funds will also be used for public outreach and community involvement /public participation process
The grant provides funding for the rerouting/realignment of sewer collection lines and abandonment of two sewer pump stations to enhance the routing of wastewater. The rerouting and abandonment of the sewer pump stations will significantly redu
The Department of Ecology received a State Clean Diesel Program Grant to fund the purchase and installation of retrofit emission control technologies on diesel powered port cargo handling equipment and retrofit idle reduction technologies on sc
ARRA MD State Clean Diesel Grant Program: Under the American Recovery Act of 2009 (ARRA), the EPA awarded grants to the Department to implement projects designed to reduce emissons from diesel vehicles. The Department will be using the funds to
ARRA MD State Clean Diesel Grant Program
Wisconsin Department of Natural Resources was awarded the State Clean Diesel Funding Assistance Program Grant to fund retrofit, replacement, and repower projects or program targeting diesel engines in Wisconsin. The general purpose of the grant
American Recovery & Reinvestment Act - Clean Diesel - Wisconsin Department of Natural Resources
The Idaho Department of Environmental Quality was awarded an American Recovery and Reinvestment Act (ARRA) Clean Diesel Program Grant to fund a retrofit and replacement project targeting school buses in Idaho.  The general purpose of the grant
American Recovery and Reinvestment Act of 2009 Idaho's ARRA Diesel Project
ENVIRONMENTAL PROTECTION, MASSACHUSETTS DEPARTMENT OF
Massachusetts Department of Environmental Protection was awarded a State Clean Diesel Program Grant to fund four projects: 1) the Waste Collection Vehicle (WCV) Retrofit Program Grant to fund a retrofit program targeting municipal and private w
Stimulus - State Clean Diesel Grant Program
We have modified our scope of work from our orginial proposal.  State of Utah Department of Environmental Quality was awarded a State Clean Diesel Program Grant to fund a retrofit project to approximently 300 school buses with DOC and CCV we ha
The federal grant provides funding to the State of Nevada to capitalize its revolving loan fund for financing the construction of drinking water facilities, green infrastructure, program administration and drinking water related activities.  Th
The award will be utilized to provide financial assistance to public waterworks for needed infrastructural improvements through the Drinking Water State Revolving Loan Program (DWSRF).  The projects will allow waterworks to provide improved ser
Federal Fiscal Year 2009 Stimulus Grant for Rock Creek Water Main Replacement
Funding through this program provides assistance to local governments for public water system improvement projects throughout Georgia in order to protect the public health through regulatory compliance and financing, water supply, and capital i
233 Peachtree Street, NEHarris Tower, Suite 900
The State Revolving Fund (SRF) award. The purpose of this grant is to invest in environmental protection and infractructure development by providing low interest loans and loan subsidies to Oregon community and non-transient community water sys
Grant to capitalize the Louisiana Drinking Water Revolving Loan Fund Program developed under Title XIV of the Safe Drinking Water Act.  ARRA FUNDS.
This is a Federal Fiscal Year 2009 Drinking Water State Revolving Fund (DWSRF) stimulus grant under the American Recovery and Reinvestment Act of 2009. It provides a source of financing throughout Montana for the construction of water treatment
This application proposes a three-year renewal of a KOI International Research Scientist Career Development Award focused on characterizing T-cell immune responses to Vibrio cholerae infection. The program will be conducted under the collaborat
T-Cell Immune Responses to Vibrio Cholerae Infection
This federal grant provides funding to the State of Nevada to assess and cleanup petroleum releases from leaking underground storage tank sites in Nevada.  The agreement will fund several activities, such as: shovel ready projects that are typi
ARRA Leaking Underground Storage Tank Program
Leaking Underground Storage Tank (LUST) - Massachusetts expects to use approximately $3.1 million dollars in stimulus money to fund the remediation of known storage tanks buried underground that are or have been compromised and are leaking petr
The award will be used to provide alternate water supplies to communities where existing water supplies have been impacted by petroleum contamination from a leaking UST.  This will be accomplished by completing municipal water line extensions o
VA LUST 2009 Stimulus - Alternate Water Supplies
This ARRA grant supports the cleanup of petroleum releases from underground storage tanks throughout Montana. Six former petroleum distribution sites are being addressed to protect groundwater, surface water, and soil contaminated with gasoline
ARRA Leaking Underground Storage Tank-Montana
The Minnesota Department of Education received funds through the American Recovery and Reinvestment Act of 2009 (ARRA) to assist in the purchase of equipment for School Food Authorities (SFAs) participating in the National School Lunch Program
DESCRIPTION 3 OVERALL PROGRAM CRITIQUE 3 PROGRESS DURING THE CURRENT FUNDING PERIOD 4 PROGRAM LEADERSHIP 5 PROGRAM AS AN INTEGRATED EFFORT 5 PROJECT AND CORE SUMMARIES OF DISCUSSION 6 BUDGETARY OVERLAP 8 COLLABORATING INSTITUTIONS 8 INDIVIDUAL
Molecular Pathogenesis of Basal-like Breast Cancer
This ARRA grant supports water quality management planning activities in Washington State.  Specific activities are: the development of 8 TMDLs (Water Quality Management Plans) and a map application design for water quality assessment data.  De
ARRA of 2009 WA Water Quality Management Planning Grant
The project that will be performed thru a contract with the United States Geological Survey (USGS) supports water quality management activities that are authorized under the Clean Water Act and the American Recovery and Reinvestment Act (ARRA)
ARRA Water Quality Management Planning Grant FY 2009 Puerto Rico Environmental Quality Board
KDHE seeks to 1) maintain core water quality monitoring, assessment, and database management functions and associated staff positions now jeopardized by the loss or diminution of traditional funding sources;  2) finalize the Kansas list of exce
KDHE 604b Recovery and Reinvestment Allocation
NATIONAL CAUCUS AND CENTER ON BLACK AGED, INC
Provides administrative support services for the Diesel Emissions Reduction Act (DERA)
This Cooperative Agreement will provide for Senior Environmental Employment (SEE) Program enrollees to work in the various offices in EPA's Region VIII Recovery and to support EPA stimulus activities with the American Recovery and Reinvestment
SEE Program for Region VIII Operations Stimulus Activities
The major goals of this project are to identify risk factors for incident Alzheimer's disease in a biracial community and to estimate prevalence and incidence of Alzheimer's disease in this community.
Risk Factors for Incident Alzheimer's Disease in a Biracial Community
Trypanosome-related disease is responsible for significant devastation of productive human lives and high mortality rates throughout the world.  The trypanosome transcriptional machinery appears to exhibit intriguing differences from the more c
Analysis of trypanosome mRNA synthesis by gene transfer
DESCRIPTION (provided by applicant): Helicobacter pylori remains the most prevalent infectious disease in the world, with up to100% of people colonized in some populations. Disease due to H. pylori is variable, however: only a minority of infec
Host and Bacterial Factors in Disease due to H. Pylori
Hepatitis C virus (HCV) is an important human pathogen with a high rate of persistence that can lead to liver cirrhosis and cancer. Given the relevance of T cells in HCV pathogenesis and emerging literature on immune function and exhaustion, we
CELLULAR IMMUNITY AND THE OUTCOME OF HEPATITIS C VIRUS INFECTION
Toxoplasma is a major opportunistic parasitic infectious agent in man and animals. Disease can result from a weak immune response resulting in parasite lysis of host tissue or it can ensue following an inappropriate immune response, leading to
Regulation of type 1 immunity to toxoplasma
Innate immunity plays a crucial role in initiating the immune responses and pathogen clearance upon microbial infection. Using pattern recognition receptors including cell surface receptor such as Toll-like receptors (TLRs) or intracellular rec
THE FUNCTION OF CARD9 IN INNATE IMMUNE RESPONSES
Interleukin 7 (IL-7) has been demonstrated to provide signals via the IL-7 receptor which are required at many stages of lymphocyte development. IL-7 receptor is composed of two different cytokine receptor subunits; the IL-7 receptor alpha chai
IL-7 RECEPTOR SIGNALING IN LYMPHOPOIESIS
We will investigate the roles of co-stimulatory molecules and soluble mediators in LNFPIII induced immune suppression.  We will perform studies to determine how the immunomodulatory glycan LNFPIII activates antigen presenting cells, focusing on
Immune Responses to Schistosome Egg Antigens
Infections caused by Staphylococcus aureus span a wide clinical spectrum, ranging from asymptomatic nasal carriage to endocarditis, bone and joint infections and lethal shock. Increasing rates of S. aureus infection and the emergence of communi
ARRA:  Virulence Determinants in Staphylococcus Bacteremia
Systemic lupus erythematosus (SLE) is an autoimmune disease. The disease develops at a female-to-male ratio of 10:1. Although, several factors, such as gene polymorphisms, female sex hormone estrogen, and interferon-signaling, are implicated in
Gender-Specific Role of p202 in Lupus Susceptibility
The amount of bone formed early in childhood is a very important determining factor in terms of whether or not the individual will develop osteoporosis later in life.  Therefore, it is great importance to understand the molecular mechanisms tha
TRANSGENIC APPROACHES TO EVALUATE IGF-I ROLE IN PEAK BMD
Food allergy is a growing and serious health concern in the United States. There is no definitive treatment for PN or other food allergies. In our initial R01 grant project, we developed Food Allergy Herbal Formula-2 (FAHF-2) and showed that it
EFFECT OF CHINESE HERBAL MEDICINE ON FOOD ALLERGY
Analyses of Progression to Colon Cancer in a Spectrum of Pathways
For metastatic prostate cancer (PCa), androgen deprivation therapy results in regression of the metastatic disease and a dramatic decrease in the serum of the androgen dependent prostate-specific antigen (PSA) protein. Eventually, all patients
Transgenic Animal Models for Prostate Cancer
ARRA WKy Rat Genetic Model for Breast Cancer Susceptibility
Work done in many laboratories has demonstrated that Ag stimulation of naive CD8 T cells can lead to different outcomes: development into effector cells and/or memory cells after immunogenic stimulation, and either activation and deletion or an
Quality and location of presented Ag as determinants of tumor-specific immunity
Mutations in a series of ppGalNAc glycosyltransferases (protein glycosylating enzymes) have recently been found in patients with colon cancer.   In this work we will study the enzymatic and biological properties of a series of mutant and wild t
Role of hsnf5/BAF47 Loss in Human Cancer Development - ARRA  The identification of tumor suppressor genes has led to new insights into the mechanisms of human cancer development.  The normal functions of these genes often lie in the control of
Role of hsnf5/BAF47 Loss in Human Cancer Development - ARRA
Oncogenesis occurs when mechanisms of cell growth control are deregulated. This generally develops in a multistep process that involves mutations in oncogenes and tumor suppressor genes. The understanding of this process has been greatly enhanc
Walleye Dermal Sarcooma Virus Accessory Protein Function
Kaposi's sarcoma-associated herpesvirus (KSHV) is causally associated with Kaposi's sarcoma (KS) and several other AIDS-related malignancies. The long-term goal of this project is to apply effective KSHV genetic and infection systems to delinea
CELL MODEL FOR KSHV INFECTION AND GENETIC MANIPULATION
This is a competing renewal application for an interdisciplinary project to develop novel multifunctional tumor targeted proapoptotic anticancer drug delivery systems (DDS) to enhance the efficiency of treatment of multidrug resistant (MDR) ova
Targeted Proapoptotic Anticancer Drug Delivery Systems
Etiology of Translocations in Hematopoietic Cells  The long-term objective of my research is to understand the influence of hematopoietic-specific developmental programs on the repair DNA damage such as double strand breaks (DSBs) and the initi
Etiology of Translocations in Hematopoietic Cells
The purpose of this award is to 1) define the repression mechanism of E2-Brd4 in HPV Chromatin and 2) to define the role of E2-P.85 in HPV Chromatin Transcription.    We will explore this possibility using our in vitro-reconstituted HPV chromat
E2-Cellular Complexes in HPV Chromatin Transcription - ARRA Stimulus 2 Yr Resub
It is estimated that over 500,000 persons across the world will die this year from hepatocellular carcinoma (HCC).  HCC is a major health problem, particularly in underdeveloped countries, and poses a series of complex health management issues.
A Novel Regulator of PI-3 Kinase in Human Liver Cancer
In the intestinal tract, the first line of defense against pathogenic microorganisms is the layer of epithelial cells that line its extensive mucosal surface. These cells provide a physical barrier to infection & play critical roles at mucosal
Mucosal Defense Mechanisms in Substance Abuse
Studies are currently underway to examine the genetic factors contributing to a range of addictions, including critical public health problems like smoking and alcohol abuse. New approaches use emerging technologies-such as genome-wide associat
Translating Addiction Genomics Research into Practice: Examining Ethics & Policy
Trafficking and signaling of opioid receptor subtypes and hetrodimers  This proposal is focused on how receptor pharmacology and trafficking are altered by co-expression/heterodimerization of the opioid receptors with a focus on heterodimers co
Trafficking and signaling of opioid receptor subtypes and hetrodimers
Ernest Gallo Clinic and Research Center, UCSF
Psychostimulants such as methylphenidate and amphetamine have become drugs of choice for the treatment of attention deficit hyperactivity disorder (ADHD). Along with falling prices for recreational stimulants like powder cocaine, stimulants are
NEUROBIOLOGY OF TRANSITION TO STIMULANT DEPENDENCE
This two-year NIDA R01 competing-continuation grant extends the work of Dr. Festinger and TRI’s section on Law & Ethics on improving the ethics of informed consent to participate in research studies.  The initial 3-year grant examined the eff
Improving the Ethics of Consent in Drug Abuse Research
'Main goal: Understand the molecular mechanisms that govern the nicotine withdrawal syndrome. Abstract. Nicotine addiction is a major worldwide medical and social problem that continues to escalate. Affective and somatic symptoms associated wit
Stress, Anxiety, and Nicotine Withdrawal
The goal of our research is to bridge the gap between basic research in cochlear physiology and clinical tools in otology such as otoacoustic emissions and cochlear implants. We will use a combination of experimental and theoretical techniques
The major intent of this project is to modify and expand a family weight gain prevention program that has previously been shown to be effective. Our previous America On the Move (AOM) Family Program, which focused on helping families make small
Diet and Physical Activity Interactions in Obesity
The long-term objectives of our research are to develop a mechanistic understanding of how cell-cell and cell-extracellular matrix adhesive interactions regulate erythropoiesis. Erythroblasts differentiate in erythroblast islands, composed of e
Novel Functions for Red Cell Proteins Lu and LW
The incidence of obesity worldwide continues to escalate with the spread of the Western diet and with it there has been a corresponding increase in cardiovascular disease, diabetes, end-stage renal disease and other obesity-related disorders. O
This competitive renewal continues to focus on the regulation of TGF-beta and Bmp7 in chronic and acute renal disease. Given that TGF-beta promotes renal interstitial fibrosis, whereas Bmp7 is thought to protect against this effect, the potenti
Congenital anomalies affecting the kidney and urinary tract are among the most common serious birth defects. While there is significant clinical and increasing genetic data on these disorders, the disease mechanisms are not well understood. The
Biochemical and Functional Studies of Sall1 in Kidney Development and TBS
DESCRIPTION (provided by applicant): The urinary tract is normally a sterile environment, kept free of microbes by the flow of urine and by myriad anti-microbial molecules and effector immune cells. However, despite these formidable host defens
BACTERIAL INVASION AND TRAFFICKING WITHIN THE BLADDER
Laser scanning microscopy (LSM), including confocal and 2-photon microscopy, continues to play a central role in many areas of biomedical research. In neuroscience alone, the number of applications continues to grow rapidly. However, in contras
Flexible, Open Source Software for Laser Scanning Microscopy
This is a competing renewal application. The overall thrust of the project is to develop novel fluorescent sensing and imaging technology for understanding the biology of zinc, with a view to developing novel and improved diagnostics and therap
Fluorescence Zinc BioSensing and Imaging Technology
The long-term objective of this research is to understand how the brain translates sensory information into the commands for movements. The oculomotor system is an excellent model for study because of its simple peripheral mechanics and muscula
Inflammatory diseases of the lacrimal gland such as Sjögren’s syndrome, sarcoidosis, and chronic graft versus-host disease or simply as occurs with advanced age, lead to inadequate secretion of the aqueous layer of the tear film, which is a
STIMULUS-SECRETION COUPLING IN DISEASED LACRIMAL GLAND
This application is in response to potential support for two years as part of the American Recovery and Reinvestment Act of 2009. The Specific Aims have been modified from the original proposal to fit 2 years of funding. The proteasome complex
The objectives of this competing renewal are to identify and characterize craniofacial (CF) disorders in mice that are reliable genetic and physiological models for human craniofacial dysmorphologies and to share these models with the scientifi
In the past 24 months, we have made progress on Aims 1 and 3; the goals of Aim 2 were completed in the previous funding period.  In Aim 1, we have now extensively examined the genetic interactions between N-cadherin and flamingo, and have found
How do photoreceptor axons choose appropriate post-synaptic partners?
DESCRIPTION (provided by applicant): The cytochromes P450 are a ubiquitous superfamily of mixed function oxidases responsible for the oxidation of a vast number of compounds including the majority of drugs used by humans. In the course of our s
PARTICIPATION IN CYTOCHROME B5 IN ANESTHETIC METABOLISM
A major challenge confronting geoscientists studying granulite-facies complexes is identifying the precursors to the rocks constituting the complexes and the tectonic environment in which they were originally deposited; the granulite-facies roc
ARRA: Application of Boron Isotopes to Constrain the Depositional Environment of the Precursors to Proterozoic Granulite-Facies Borosilicate Paragneisses,
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).  This grant supports acquisition of a high temperature (up to 200°C), high pressure (up to 70 MPa) capable, multi (3) triaxial cell, rock deforma
Acquisition of a High-Pressure High-Temperature Load and Flow-Through System for Research and Teaching
Collaborative Research: Chromium Isotopes as Redox-Indicators-Oxidation and Istopic Equilibration Experiments
The NSF REU Dune Undergraduate Geomorphology and Geochronology (DUGG) project will address how and why dunes formed in various environments in the state of Wisconsin.  The goals of this project include providing students with significant earth
Research Experiences for Undergraduates (REU)-Site Collaborative Research Dune Undergraduate Geomorphology and Geochronology (DUGG) Project in Wisconsin
This project investigates time-varying fault-zone strength at seismogenic depth that will effect the triggering and sequencing of earthquakes, by taking advantage of the numerous identified repeating earthquakes accumulating from a dense boreho
An Investigation into Time-Dependent Fault Zone Properties at Seismogenic Depth on the San Andreas Fault Near Parkfield
The research outlined in this proposal is meant to both complement and expand our current knowledge of Proterozoic paleogeography and, in particular, the supercontinents of Gondwana, Rodinia and Columbia.  Paleomagnetic data (in combination wit
Further Refinement of India's Proterozoic Paleogeography and Geochronology.
Magma that feeds volcanic eruptions on oceanic islands and most of the deep ocean is produced by melting of the underlying mantle. Current knowledge of the details of magma genesis and transport are derived from observations of eruption rates a
The Mantle Melt Column and Melt Migration Revealed by Deglaciation Melting Beneath Iceland's Western Rift Zone
The award is supporting research into improved methods of global and regional scale seismic tomography in order to better constrain models of flow in the Earth's mantle.  This research will verify a proposed method of modeling surface waves and
ABSTRACT 'This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).' Hyporheic zones and riparian zones play important roles in catchment-scale budgets of nutrients, heat, and energy. Significant research
What are the seasonal controls on stream-riparian groundwater exchange during baseflow recession in headwater catchments?
This project seeks to further our understanding of the distribution of frictional properties on faults, which is essential for assessing seismic potential of faults. The idealized view of coupling involving an interseismically locked section th
Estimating Frictional Properties of Faults from Geodetic Data
The principal investigator is investigating the structural and metamorphic history of the Foxe Fold Belt (FFB) in Nunavut, Canada. Orientations of fold hinge lines and related structures yield invaluable information about past relative movement
The kinematic significance of folds in the Paleoproterozoic Foxe  Fold Belt, Melville Peninsula, Nunavut, Canada
This project will investigate the origin of large, striking landforms that occur in areas of thick loess (sediment formed by deposition of wind-blown dust), in North America, northern China, and central Europe.  These landforms include features
Collaborative Research: Linking Loess Landforms and Eolian Processes.
Development of Electronic Systems for Noble Gas Analysis: this award presents a plan for instrument development to address the strong demand for inexpensive, high precision analyses of noble gases by many Earth scientists in the U.S. and worldw
Development of Electronic Systems for Noble Mass Spectrometers
This work develops and applies new advanced methods of imaging, or 'seeing', the structures of proteins and how they work, very much in the spirit of the development of, for example, magnetic resonance imaging methods developed in the last cent
IMAGING ENZYME STRUCTURE AND DYNAMICS: SPECIFIC FUNCTION AND FUNCTIONAL DIVERSITY
The objective of this research is to develop a low-cost non-destructive, non-contact probing method for surface and sub-surface characterization of inhomogeneous materials and devices. New artificial and nano-material development requires fast,
Hybrid Electromagnetic Near-Field Probing for Sub-surface Inhomogeneous Material Characterization
Description of the Instrument: The project is for the acquisition of a Raith e-line electron beam lithography system, which is capable of defining feature sizes < 20 nm over large areas (4”x4”).      The instrument is also capable of doing
MRI: Acquisition of Nanolithography Equipment
NEW MEXICO INSTITUTE OF MINING AND TECHNOLOGY
at the THz spectral region, by developing the first generation of THz graphene-based photodetectors with exceptional sensitivity, dynamic range, response rate and non-cryogenic operating temperatures.  The approach is based on monitoring condu
Collaborative Research:  Graphene-based THz Photodetectors
Effective mid-year 2011, funding from the Efficiency Kansas loan program was re-directed to 5 energy efficiency retrofits at our State's Regent's Centers and 2 commercial projects sub-granted to the Kansas Department of Commerce.  The Energy Di
American Recovery and Reinvestment Act (ARRA)-Kansas
DEPARTMENT OF LICENSING AND REGULATORY AFFAIRS
Recovery Act:  State of Michigan Energy Efficiency and Conservation Block Grant
THE PURPOSE OF THIS AWARD IS TO IMPLEMENT THE RECIPIENT'S ENERGY EFFICIENCY AND CONSERVATION STRATEGY (EEC&S) IN ORDER TO REDUCE FOSSIL FUEL EMISSIONS; REDUCE TOTAL ENERGY USE OF THE ELIGIBLE ENTITIES; AND IMPROVE ENERGY EFFICIENCY IN THE BUILD
Energy Efficiency and Conservation Block Grant program
Ground Source Heat Pump Installation at 8 local recreation center gymnasiums
The funding under this award is for the purpose of energy efficiency. The project to be funded is for energy efficiency improvement for tribally owned street lights.  The Project will take place at the Nation’s Village of the White Pines, a r
Oneida Nation Solar Street Lighting Energy Efficiency Upgrade Project
Omaha Tribe was funded to develop an Energy Efficiency & Conservation Strategy as well as to addressss the energy efficiency retrofits for the tribal government buildings.
Omaha Tribe Energy Efficiency & Conservation Project
New Jersey Board of Public Utilities, Office of Clean Energy worked closely with the Clean Energy Market Managers in submitting  New Jersey's SEEARP plan which was due October 15, 2009.  We received approval from the Board on October 7, 2009 to
STATE ENERGY EFFICIENT APPLIANCE REBATE PROGRAM (SEEARP)
2004350 - EE Conservation Block Grant Program.
The City of Poway would like to expand its conservation efforts to 1) launch a program which facilitates energy efficiency and solar retrofits on properties city- wide by providing streamlined contracting and financing services, while deliverin
Municipal Energy Efficiency Improvements, Poway Community Residential Rebate Program
Municipal Center Bike Path/Pedestrian Walkway
City of East Point Energy Efficiency and Conservation Block Grant to provide energy audits and retrofits to residents of East Point; establish a biodiesel program; develop a comprehensive energy conservation strategy; and purchase propane power
Energy reduction renovation project Millsop Community Center
TAS::89 0331::TAS Recovery Recovery Act EECBG
This three-year REU site program at the University of Hawaii will provide research experiences for ten undergraduate students each year in the area of Engineering Applications of Computational Fluid Dynamics (CFD) using High Performance Computi
Research Experiences for Undergraduate (REU) Site: University of Hawai'i (UH) High Performance Computing (HPC) Computational Fluid Dynamics (CFD) Applications in Engineering
Some of the major obstacles preventing the successful creation of stem cell therapies include accurately and reproducibly controlling the differentiation of stem cells, and creating a sufficient amount of cells for therapeutic procedures. These
BRIGE: Minority Education and Research in Biomedical Microdevices - An Optically Controlled Cell Culturing and Harvesting Platform
. The project is focused on the development and evaluation of innovative instructional environment by integrating virtual reality (VR) based interactive 3Dsimulations into undegraduate curriculum. The project is conducted in collaboration with
Collaborative Research: Virtual Reality-Based Education Laboratories in Fiber Optic Engineering
in a manner which helps those who seek to start or refine activities. The results will be made available through conferences, publications and a dedicated internet site where interested parties may view and contribute. The overall goal is to b
Collaborative Proposal: Evaluation of Sustainable Engineering Education via Service Learning Efforts in Engineering
This project, entitled: 'Integration of Nanotechnology into Undergraduate Engineering and Science Education,' is under the direction of Lihong (Heidi)Jia, Nael A. Barakat.
Integration of Nanotechnology into Undergraduate Engineering and Science Education
Ohio received a National Emergency Grant (CFDA 17.260) to provide employment and training services to workers displaced from the GE Lighting facility in Willoughby, Ohio. Total Funding for OH-20 is $271,075.
OH-20 GE Lighting National Emergency Grant (CFDA 17.260)
STATE OF MINNESOTA DEPARTMENT OF EMPLOYMENT & ECONOMIC DEVELOPMENT, THE
The Dislocated Worker-National Emergency Grant (NEG) program serves laid-off workers and the businesses that hire them. Under Recovery Act, Minnesota gives priority to those individuals who want to receive credentialed training for high-growth/
Dislocated Worker-National Emergency Grant - MARS
The overall purpose of the WIA National Emergency Grant Dual Enrollment award through the U.S. Department of Labor is to assist those most impacted by the recession. The NEG funds assist dislocated Oregonians who lost their jobs at specific com
National Emergency Grant-GE Security Dual Enrollment
RESOURCES AND ECONOMIC DEVELOPMENT, NEW HAMPSHIRE DEPARTMENT OF
This grant application was modified effective June 22, 2010 to reduce the grant award to $278,591 and the number of individuals to be served to 84. This program provide for project management and delivery of dislocated worker services to disloc
NEG Manufacturing Industry (ARRA) Project No. NH-10
The overall purpose of the WIA National Emergency ARRA Grant award through the U.S. Department of Labor is to assist those most impacted by the recession. The NEG funds assist dislocated Oregonians who lost their jobs at specific companies due
National Emergency Grant - Sauer Danfoss
WIA Dislocated Worker, National Reserve Emergency Grant, ARRA
WIA Dislocated Worker, National Reserve Emergency Grant - John Deere/Alcoa
BETHLEHEM COMMUNITY VOLUNTEER FIRE DEPARTMENT, INC
American Recovery and Reinvestment Act Assistance to Firefighters Station Construction Grants (ARRA-SCG)
POSEY TOWNSHIP CLAY COUNTY VOLUNTEER FIRE DEPT INC
Firefighters Fire Station Construction Grant
Under the ARRA Fire Station Construction Grant, we were approved for $209,000 to rebuild our existing fire station.
Under WA 2-200 Title of Work Assignment: “RECOVERY:  Engineering and Technical Support for Technical and Engineering Assistance for American Recovery and Reinvestment Act (ARRA) Water Projects in West Virginia”.
Protect public health by reducing exposure to contaminants in drinking water through technical support to the Drinking Water State Revolving Fund's ARRA programs.
The partnership between South Carolina (SC) and Tennessee (TN) is based on existing and planned collaborations in advanced materials and systems biology research, and in knowledge domains where computational science is driving new approaches an
Collaborative Research: An EPSCoR Desktop to Teragrid EcoSystem
The EPA's Targeted Brownfields Assessment (TBA) program is designed to assist states, tribes and local governments to minimize the uncertainties of contamination often associated with brownfields. TBAs supplement and help support other efforts
The EPA Targeted Brownfields Assessment (TBA) Program is designed to assist states, tribes, and local government agencies to minimize the uncertainties of contamination often associated with brownfields.  TBAs supplement and help support respon
CDM has been tasked to continue the placement of mine wastes and contaminated soils at the Luttrell repository and the layback, or reduction of the steepness, of the highwalls at the repository. The highwall layback is necessary for safe waste
TAS::68 8195::TAS RECOVERY -- THE PURPOSE OF THIS TASK ORDER IS TO OBLIGATE $60K FOR TBA OF THE WHEAT RIDGE 44TH & WADSWORTH SITE, WHEAT RIDGE, CO.  THE POP IS FROM DATE OF AWARD THROUGH 11/30/09.  THIS WORK IS TO PROVIDE A TARGETED BROWNFIELDS
and develop Analysis of Brownfield Cleanup Alternative (ABCA) describing cleanup options and cost estimate for cleanup,  This task order is only for a single site (Arcade Mill), which was completed as a multi-site requirement under TO4014 file
BRISTOL ENVIRONMENTAL REMEDIATION SERVICES LLC
Work will consist of conducting a site assessment at two locations where underground storage tanks may be present at the Chief's Place and White Earth Grocery sites on the White Earth Reservation in White Earth, Minnesota.  If present, tanks an
Work will consist of conducting a Tier 2 site assessment and source area soil removal at the former Skelly station on the Winnebago Indian Reservation in Winnebago, Nebraska.  To assess the soil, underground storage tanks and piping will be rem
Conduct a site assessment at the former Starvin Marvin service station on the Flathead Indian Reservation in St. Ignatius, Montana.  Site assessment activities include the installation of soil borings and the collection of soil and groundwater
CDM received work assignment 020-SION-0200 under the United States Environmental Protection Agency's Response Action Contract 2 to perform a Targeted Brownfields Assessment (TBA) at the Former Grand Union site, located at 354 Broadway, Fort Edw
Group 17 Enhancement Project (Packenham (Derbigny - Genie)
We are studying the mechanism of the catalytic reaction that converts molecular nitrogen into ammonia by the bacterial enzyme nitrogenase. For the catalytically central iron-molybdenum cofactor duster in nitrogenase, we will examine geometric a
Electronic Structure of Iron-Sulfur and Related Proteins
Long distance electron transfer plays an important role in biological function in many enzymes. In these reactions, radical transport may occur and may involve transfer of an electron alone (ET) or a proton coupled, electron transfer reaction (
ARRA: SPECTROSCOPIC STUDIES OF LIGHT-DRIVEN ELECTRON TRANSFER
A fundamental feature of a living system is the integrated network of biochemical pathways and processes that generate a balanced and robust metabolism. The long term goal of the research in my laboratory is to contribute to our understanding o
ARRA New metabolic inputs into synthesis of the pyrimidine of thiamine
The goal of this proposal is a molecular level description of protein unfolding, and by extension folding, using realistic molecular dynamics (MD) simulations in solution. Both the general and sequence-specific rules of unfolding will be pursue
Molecular Dynamics Simulations of Protein Unfolding
The Protein-target interaction is one of the most important processes occurring in biological systems. One subgroup of such interactions takes place with a dramatic change in the secondary structure: from unstructured (coil) when it is unbound
Role of Helix Formation in Mediating Protein-Protein Interactions
Voltage-gated ion channels (VGC) are proteins found in the membranes of practically all cells and that through opening and closing (gating) events let ions flow through between the internal and external milieu of the cells acting as very fast s
VOLTAGE-GATING IN BACTERIAL ION CHANNELS
Award Title: Developmental Control of Spindle Positioning in Embryos Description: The goal of the grant is to elucidate the molecular mechanisms that control the position of the mitotic spindle during development, using the nematode C. elegans
Developmental Control of Spindle Positioning in Embryos
Department of Molecular and Cellular Biology
The primary objective of this project is to understand the signaling mechanism of light activated sensory rhodopsins (SRs), part of the growing family of 7-helix transmembrane microbial rhodopsins. Examples of SRs include SRI and SRII from arch
FTIR STUDY OF SIGNAL TRANSDUCTION IN SENSORY RHODOPSINS
The developmental mechanisms of human and Drosophila blood systems show remarkable parallels. Most genes essential for the formation and maturation of Drosophila hemocytes are conserved in humans and the majority is associated with hematopoieti
The pituitary gland contains individualized cell types that specialize in the production of individual hormones. Understanding the mechanisms that underlie the transition from proliferation to cell differentiation is important because many body
CELL SPECIFIC EXPRESSION IN THE PITUITARY GLAND
Totally blind people with no light perception cannot synchronize (entrain) their circadian rhythms to the light/dark cycle. Nevertheless, about half of these people are entrained to the 24- hour day. The time cues for entrainment are not known
MELATONIN STUDIES OF TOTALY BLIND CHILDREN
This competitive renewal application is to continue on going studies in mice aimed at our long held goal of generating knowledge that can be used to mitigate, and remediate, alveolar loss in individuals with chronic obstructive pulmonary diseas
The Aims stem from our initial investigations of enzymes that metabolize peptides such as bradykinin (BK), angiotensins and others. Inhibitors of angiotensin I converting enzyme (kininase II; ACE) are currently used to treat millions of patient
Vasoactive Peptides that Stimulate Smooth Muscles
A detailed comprehension of the role of the thrombospondins (TSPs), including cartilage oligomeric matrix protein (COMP), in the regulation of extracellular matrix (ECM) structure and cellular behavior during tissue genesis and repair is the lo
This proposal is focused on the altered neuronal control of coronary blood flow and the impact on ventricular function during exercise in heart failure as well as the role of vasoconstriction in active skeletal muscle in mediating the exaggerat
BLOOD PRESSURE CONTROL DURING EXERCISE IN HEART FAILURE
The coagulation cascade is initiated by binding of the coagulation factor VII(a) (FVIIa) to its cell surface receptor, tissue factor (TF). An aberrant expression of TF is the primary reason for thrombotic disorders associated with various disea
Initiation and Regulation of Blood Coagulation
Description (provided by applicant): The Two Process model of homeostatic sleep regulation posits that the timing of sleep is due to the interaction between a circadian process (Process C) and a homeostatically regulated sleep process (Process
NEURAL GENE EXPRESSION IN SLEEP DEPRIVATION AND RECOVERY
We previously reported that sodium excretion is significantly correlated to the excretion of nitrate/nitrite (metabolites of nitric oxide) in normotensive young adults. This association of the nitric oxide pathway with sodium excretion in human
NITRIC OXIDE SYNTHASE ISOFORMS IN THE KIDNEY
Activation of the endothelial cells that line blood vessels during inflammatory processes such as those associated with cardiovascular disease results in the recruitment of circulating white blood cells into the vessel wall that can ultimately
ADAM17-mediated Shedding in Endothelial Inflammatory Responses
In this two-year AARA grant application, we propose to continue our investigation into 4D image reconstruction methods to further improve the quality and quantitative accuracy of 4D gated myocardial perfusion (GMP) emission computed tomography
TASK-BASED OPTIMIZATION FOR GATED MYOCARDIAL ECT
Atherosclerotic coronary artery disease is the largest single killer of Americans and the most complex subset of these patients have decreased heart function because of the blockage in their coronary arteries.  Coronary bypass surgery and coron
3D MYOCARDIAL STRAIN VECTORS IN ISCHEMIC HEART DISEASE
Alterations in cardiac lipid metabolism are associated with heart failure in patients with diabetes and obesity. Excess dietary fat is also thought to be deleterious. Fatty acids (FAs) and glucose supply energy to all tissues of the body, howev
Mechanisms of Fatty Acid Uptake By Cardiac Muscle
It is clear that the tissue microenvironment plays a critical role in regulating inflammation and tissue destruction. Chronic inflammation and tissue fibrosis lead not only to increased turnover of the extracellular matrix but also to an increa
HYALURONAN-INDUCED SIGNALING AND GENE REGULATION
The mechanisms regulating acute inflammation with severe sepsis need to be better defined to design treatments that can be used to protect the lungs and prevent death from multiple organ failure. Pulmonary macrophages are immune-effector cells
Macrophage Gene Expression in Acute Lung Inflammation
5-Oxo-ETE has the qualifications of an important physiological mediator: It is formed by a highly selective enzyme 5-hydroxyeicosanoid dehydrogenase (5-HEDH). Its actions are mediated by the selective OXE receptor (OXE-R), and metabolism by var
5-Oxo-ETE Antagonist.  A Novel Asthma Therapy
In previous work, we have developed, deployed and evaluated a novel intelligent medical training system for pathologic diagnosis and reporting. SlideTutor is an individualized, adaptive, simulation environment that provides explanations and ass
Computational Methods for Personalized and Adaptive Cognitive Training
The proposed research is directed at the study of growth-associated protein GAP-43, an essential presynaptic protein with critical functions in neural development (axonal pathfinding), and plasticity (long-term potentiation, learning and memory
Synaptic Dialogue Leading to Information Storage
The goal of this award is to generate an inducible knockin mouse targeting the Plp1 gene on the X-chromosome. Mutations in the PLP1 gene cause Pelizaeus-Merzbacker disease, and we have determined that a major in the pathophysiology is a protein
This ARRA application represents an extension of RO1-44351, the first prospective cohort investigation of children with new onset epilepsy designed to characterize the etiology and natural history of neurodevelopmental abnormalities in cognitio
ARRA Neuropsychological Progression in New Onset Epilepsy
Cyclooxygenase-2 (COX-2) is the inducible form of cyclooxygenase and catalyzes the rate- limiting step in the formation of prostaglandins from arachidonic acid. COX-2 expression and prostaglandin production increase markedly in neurons followin
Protective prostaglandin receptors in cerebral ischemia
Hypoxic cell death in the form of stroke and myocardial infarction is the largest single cause of death in theUnited States. The fundamental molecular mechanisms of hypoxic cell death are incompletely understood.Studies in genetically tractable
GENETIC ANALYSIS OF HYPOXIC DEATH IN C ELEGANS
Many acid-base transporters contribute to intracellular and extracellular pH regulation in brain. Electrogenic Na/Bicarbonate Cotransporters (NBCs) are particularly important because they alter pH in response to neuronal activity. While the phy
Muscle degeneration underlies many forms of muscular dystrophy and may also contribute significantlyto the decline of muscle mass associated with the normal aging process. Limb Girdle MuscularDystrophy 2B is a recessive form of muscular dystrop
MYOFERLIN IN MUSCLE MEMBRANE FUSION AND REPAIR
The 2,4-thiazolidinedione (TZD) ring is found in currently marketed and investigational therapeutic agents. This is a potential human health concern since hepatotoxicity was reported in some patients taking TZD ring containing drugs. An example
Our society must make difficult policy decisions about complex biomedical research and treatment issues without the scientific understanding or expertise to critically evaluate these issues. So, while scientists understanding of the effects of
Addiction Studies Program for Journalists
Despite the availability of newer antimicrobial agents, improved supportive care, and the introduction of an FDA approved adjunctive therapy for sepsis, (Xigris(r), drotrecogin alfa), the mortality rate for severe sepsis and septic shock of 30-
A NOVEL DRUG FOR SEPTICEMIA TARGETS A1 ARS
A Novel Therapy for Staphylococcal Enterotoxin B Poisoning is a research grant aimed at developing a soy-based vaccine for Enterotoxin B Poisoning, which is a potential weapon of bioterrorism. Currently, no effective vaccine exists that provide
A Novel Therapy for Staphylococcal Enterotoxin B Poisoning
Psoriasis is a chronic, inflammatory, hyper-proliferative skin disease that affects nearly 80 million people worldwide. During Phase 1, cells from involved psoriatic lesions were harvested, proliferated in monolayer culture, and cryopreserved.
Title: Ocular Insert for Non-Invasive Sustained Drug Delivery for the Treatment of Glaucoma.   Through Phase I and Phase II SBIR Grant Awards, Vista Scientific has developed and combined two unique drug delivery technologies that can resolve se
Ocular Insert for Non-Invasive Sustained Drug Delivery for the Treatment of Glaucoma
Our goal is to understand the induction of HIV-1 transcription by the viral Tat protein, and its connection to other steps needed to process viral mRNAs and facilitate their export out of the nucleus. The HIV-1 Tat protein works with the host c
Nuclear factor-KB (NF-?B) is a transcription factor that plays many essential roles in immune responses in vivo, from contributing to the formation of lymph nodes and Peyer's patches to allowing generation and maturation of dendritic cells and
ROLE OF NF-KB ACTIVATION IN ACUTE ALLOGRAFT REJECTION
costimulatory molecules leading to full activation. Other costimulatory molecules such as CTLA4 provide a negative signal (co-inhibitory) for T cell activation and may be important for terminating immune responses. Recently, other pathways tha
Role and mechanism of negative costimulatory pathways in EAE
Poliovirus is the best-known member of a large family of viruses that have genomes made of RNA. These viruses carry a gene for a very specific RNA dependent RNA polymerase protein that is responsible for replicating the virus genome. The focus
Assembly of Picornaviral Replication Complexes
Galactofuranose (Galf) residues have been implicated in the virulence or viability of many microbes, including mycobacteria. The goal of the proposed research is to understand the mechanisms underlying Galf residue incorporation into the mycoba
ARRA The Chemistry and Biology of Galactofuranose Residues
Diabetes affects 24 million Americans, 220 million people worldwide, and is the 6th leading cause of death in the US. Diabetic nephropathy (DN) is the most common cause of kidney failure in the US. This chronic and debilitating disease is chara
AT1 RECEPTORS IN RENAL MICROVASCULAR PHYSIOLOGY
Adenosine modulates many important physiological processes by triggering ubiquitously expressed adenosine receptors. This project is focused on ecto-5?-nucleotidase (CD73), a glycosyl phosphatidylinositol (GPI)-linked membrane protein that cata
The Regulation of Inflammatory Responses by CD73
ERP CR4 /ABANAKEE LK (BIN 3307220) BR REPLACE, T/INDIAN LAKE
The training grant 'Aging Health and Health Services Research' addresses all 4 of the major goals of the NIA Strategic Plan for research, by educating well trained researchers, with multi-disciplinary experience and a broad understanding of the
AGING HEALTH AND HEALTH SERVICES RESEARCH TRAINING
This agreement provides funding under the American Recovery and Reinvestment Act of 2009 to the State of Maine to capitalize its revolving loan fund for the financing for the construction of wastewater treatment facilities and associated infras
Capitalization Grant for the Clean Water State Revolving Fund
This agreement provides funding under the ARRA of 2009 to the State of South Carolina to capitalize its revolving loan fund for the financing for the construction of wastewater treatment facilities and assoicated infrastructure, green infrastru
The award will be used to fund infrastructure improvements to publicly owned wastewater systems and non-point water quality projects.  The outcomes will be operational and maintenance improvements, public health protection, and wastewater quali
Administration of Clean Water State Revolving Loan Fund (CWSRF) projects using funds provided under the American Recovery and Reinvestment Act (ARRA) of 2009.  The following types of projects will be funded with CWSRF ARRA funds:  wastewater tr
This award provides a source of financing for the construction of wastewater treatment facilities and associated infrastructure, green infrastructure, estuary projects and program administration.  The primary purposes of the simulus grant throu
Emergency Food Assistance - The Wisconsin Department of Health Services (DHS) used ARRA funds to pay for costs associated with the distribution of USDA foods. The funds helped to supplement the usual administrative costs associated with the sto
This project seeks to create a new employment opportunity in an active NIA parent grant. The parent grant is a research scientist training award (1K01AG031836-01A1) with a potentially important and ambitious research program on cost-related non
Cost-related Underuse of Medications and the Health of Older Adults
Estrogen exposure correlates with a reduced risk of colorectal cancer (CRC). Nonetheless, little is known about the mechanisms through which estrogens protect against CRC. At least some of the effects of estrogens on CRC are likely mediated via
Eralpha Regulation of Intestinal Homeostasis & Tumorigenesis
Adipocyte Insulin Signaling in Metabolism and Aging - This is a request for an  administrative supplement to NIH grant 1 K08 AG032869-01 entitled “Adipocyte Insulin Signaling in Metabolism and Aging”. Permanently blocking the ability of ins
Adipocyte Insulin Signaling in Metabolism and Aging
Project Summary Naturally occurring sequences capable of forming H-DNA (triplexes) are found in the human genome as frequently as 1 in every 50,000 base pairs.  These sequences are typically found in promoters and exons and are believed to be i
Altered Helica Structures: Repair and Induction of Genomic Instability
Rural areas are often medically underserved and represent about 20% of the U.S. population.  Telemedicine holds considerable promise in alleviating many constraints imposed by time and distance on subspecialty health care encounters.  As a cons
Center for Translational Neuroscience (COBRE)
Center for Translational Neuroscience TELEMEDICINE (COBRE). This is a supplement for the development of an Emergency Department Physicians Learning and Collaborative Education program, linking 5 emergency departments with the academic instituti
Center for Translational Neuroscience TELEMEDICINE (COBRE)
The UNMC Eppley Cancer Center is an NCI-designated matrix Clinical Cancer Center at the University of Nebraska Medical Center (UNMC) conducting a wide range of basic, clinical, translational and population science cancer research. The Cancer Ce
The Center for Ulcer Research and Education (CURE) was founded nearly 35 years ago by Dr. Morton I. Grossman, a pioneer of gastrointestinal (GI) endocrinology. Its original mission was the study and cure of peptic ulcer disease. Over the years,
CURE: DIGESTIVE DISEASES RESEARCH CENTER
'We propose to enrich the technology infrastructure of our Cryo-EM P41 CenterWe propose to enrich the technology infrastructure of our Cryo-EM P41 Center by 1) automating the cryospecimen preparation with microfluidity and robotics engineering
3 D Electron Microscopy of Macromolecules
Our work in both rodents and primates has indicated that the biochemical and behavioral effects of withdrawal from repeated phencyclidine (PCP) form a useful model of the cognitive deficits of schizophrenia. PCP exposure imparts a lasting and r
Chronic PCP primate PFC dopamine Deficit and Schizophrenia
The proposed supplement will fund a summer research experience for four local science educators from non-research-intensive colleges and universities in the New Haven, CT-area to work on a double-blind, placebo controlled trial to test the effi
Naltrexone for Heavy drinking in young adults
Title: An in vitro Model for HIV Latency in Primary Cells  We have requested this supplement to provide an opportunity to rapidly accelerate identification of compounds with potential clinical utility in activation/elimination therapeutic strat
AN IN VITRO MODEL FOR HIV LATENCY IN PRIMARY CELLS
This supplement application is for the purpose of immediately purchasing a Fast Protein Liquid Chromatography (FPLC) system that will greatly increase the throughput and tempo of the research projects outlined in the parent R01 grant (DA026423)
Antibody-nanoparticle conjugates for the treatment of methamphetamine abuse
Sensorimotor Control of the Human Orafacial System
City of Washington Resurfacing of Various Streets
The purpose of this funding is to enhance services at the state's One-Stop Career Centers that provide a variety of job search assistance and information services without charge to unemployment insurance claimants and other job seekers and to e
Wagner Peyser Act Employment Services - ARRA
Wagner-Peyser (W-P) services assist job seekers through WorkForceCenters. Services provided include job search assistance, job placement assistance, skills assessment, career guidance using specially developed tools that tie local and regional
ARRA funding allocations were awarded to supplement PY 2008 Wagner-Peyser Act base allotments and add Reemployment Service funding per TEGL 13-08. The purpose of the RES and ES stimulus is to provide additional reemployment and job placement se
Chapman Avenue from Main Street to 300 feet east of Pixley Street and from Hewes Street to 100 feet east of Cannon Street
ADA PED ACCESS REGION FOUR - PRICE DISTRICT
SR-107: 4000 WEST TO 4050 WEST, WEST POINT
SIGNAL DETECTION UPGRADES FOR WEBER/DAVIS COUNTIES
I-15 FIBER INSTALL, LAYTON TO RIVERDALE ROAD
SR-198; VARIOUS LOCATIONS PAYSON TO SANTAQUIN
SALEM AVE: SHERMAN ST-UP RAILROAD PAVEMENT OVERLAY
HERSEY ST: OAK ST-ANN ST SIDEWALK (ASHLAND)
2 IN PAVEMENT OVERLAY IN ACCORDANCE WITH 1R GUIDELINES
Recovery funds- Arts & Industries Bldg Masonry Repairs Construction Phase Services
Provide all supervision, labor, material and equipment for Removal and Replacement of the Fire Protection in the Visitor Center and the Propagation Buildings & Boiler Plant
SEC shall furnish all supervision, labor, materials,and equipment necessary to complete escalator repair and upgrade work at NASM, as well as elevator upgrade work at the NMAH
NZP Rock Creek Police Station and Outlying buildings
CONSTRUCT CURB,GUTTER, SIDEWALK AND PAVED SHOULDER
S 8TH ST & WOODSON BRDG APPROACH (COTTAGE GROVE)
This project will provide for the construction pertaining to: full-scale replacement or overlay to the existing roof, including but not limited to:   replace flashings, seals, full membrane systems, roof-to-wall transitions, underlayments, and
This project will provide for the construction pertaining to: full-scale replacement or overlay to the existing metal roof, including but not limited to:   replace flashings, seals, metal panels, roof-to-wall transitions, underlayments, structu
This project will repair the parking lot located at 4th and F Ave. on the east side of KAFB. Repairs include removal and replacement of various asphalt and concrete paving improvements,  striping, drainage improvements, traffic signage improvem
This project will evaluate three compressed air systems in three buildings on Kirtland AFB and will repair leaks in these systems as a means to decrease the energy consumption.   The project requirements include providing engineering schematics
This project will repair paving improvements in the Maxwell Housing Area between Gibson Boulevard and B1900. Repairs include removal and replacement of various asphalt and concrete paving improvements, striping,  traffic signalization/signage i
Viral evasion of global RNA turnover during gammaherpesvirus lytic infection. Our understanding of the life cycle of cancer-causing gammaherpesviruses is limited. We will attempt to elucidate the means by which these viruses actively replicate
Viral Evasion of Global RNA Turnover During Gammaherpesvirus Lytic Infection
SPRUCE STREET: MONROE AVENUE - Z AVENUE (LAGRANDE)
GRIND AND REPLACE 2 IN OF ASPHALT SURFACE IN ACCORDANCE WITH 1R GUIDELINES
ROYCE & MCNARY ST: PVMT GRIND/OVERLAY(LAKE OSWEGO)
CONSTRUCT SIDEWALKS, CURB/DRAINAGE, LANDSCAPING&#59; ARRA FUNDS FOR ADDITIONAL LIGHTING
US26: MAIN ST SIDEWALKS & STREETSCAPE (MT VERNON)
SPRINGWATER TRAIL: UPRR BRDG-EAST CITY BORDER
SHERWOOD BLVD: 3RD ST-LANGER DR OVERLAY (SHERWOOD)
MODIFY TRAFFIC SIGNALS TO INCREASE CAPACITY AND SAFETY
TRAFFIC SIGNAL REHAB & STREET LIGHT REPL (SPRGFLD)
This project is to provide construction inspection services for Fire Station, Phase 2 at the Utah Air National Guard Base, Salt Lake City, UT. Project includes a Mobility Processing Center and an Explosive Ordinance Disposal (EOD) Facility, ass
Remove old joint sealant and replace with new LOX sealant. The purpose is to facilitate government testing.
Remove metal handrails and replace with framed walls
REPAIR CENTER AND SOUTH SECTION OF ROOF.
Replace HVAC System in Facility 62820 at CCAFS, FL.
Replace HVAC System in Hangar Y, Facility 1115, CCAFS, FL.
Replace Windows and Doors - South Chapel, Patrick Air Force Base, FL.  The purpose of this contract is to replace all windows located at the South Chapel of Patrick Air Froce Base, FL located at 3659 Falcon Ave.  All existing doors and windows
The contractor shall furnish all management, supervision, labor, materials, equipment, and incidentals required for a broad range of maintenance, repair and minor construction work on various facilities on Schriever AFA, CO to include design an
Execute Paving Construction Projects and Steam and Condensate Construction Projects
Execute Steam and Condensate Construction Projects
Received Modification A00008 to Prime Contract FA3002-08-C-0001 on 12 May 09 with ARRA funding to repair the chiller at Locker House in the amount of $277,342.55.  Mod A00047 revised amount to $276,311. CSC solicited 3 vendors to bid on the pro
Firm fixed price/Project Description:  Conduct Spill Prevention Control and Countermeasures (SPCC) mandated Shop-built Above-ground Storage Tank (AST) inspections
COMMERCIAL AND INSTITUTIONAL BUILDING CONSTRUCTION
The project is for AFCESA Project #HOLL-09-S-2840, Repair Hangarettes, B21808 and B21812, with the potential to add other hangarettes by modification.  The project is located in Otero County, NM, at Holloman AFB.  The project purpose is to repa
Extend water piping for fire protection in training area.
1001-REPAIR THE TRAINING APRON, PHASE 1. INCLUDES: 1002-SAWCUT CONCRETE PAVEMENT. 1003-FORM AND SEAL EXPANSION JOINTS. 1004-FORM,SAW, AND SEAL CONSTRUCTION JOINTS. 1005-SAW,SEAL CONTRACT/CONSTRUCT JOINTS. 1006-CONCRETE PAVEMENT DEMOLITION. 1007
SABER TASK ORDER 5020,FA302009D0004,REPLACE CHILLED WATER PIPING BLDG. 370.**REPLACE CHILLED WATER PIPING, WINDOWS,AND STAIRS.ORIGINAL CONTRACT MODIFIED INCREASING CONTRACT TO $1222458.00 AN INCREASE OF $151902.00. MOD 9 INCREASED CONTRACT AMOU
Repair Range Rd. from Gapco to Kellac St.
PAINTING IDIQ/REPAIR AND PAINT 1ST FLOOR INTERIOR B/10656    ESP:OQ - LACKLAND AFB
PAINTING IDIQ-REPAIR AND PAINT EXTERIOR BLDG 10070  ESP:9Q - LACKLAND AFB
PAINTING IDIQ/REPAIR AND PAINT EXTERIOR 1ST FLOOR B/10055   ESP:JJ - LACKLAND AFB
In cystic fibrosis (CF), mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel are associated with defective cAMP and acid-stimulated duodenal bicarbonate secretion, and defective cAMP and cGMP-activated f
Functional Relevance of CFTR Trafficking in Vivo to Intestinal Disease
We hypothesize that deletion of GABAergic funciton of accumbens shell neurons will lead to constant disinhibition of target areas including the lateral hypothalamus, resultingin hyperphagia on palatable food and development of obesity.
Non-Homeostatic Neural Controls of Food Intake
Funds were requested to support two undergraduate students summer research. One student employed high-throughput yeast two-hybrid assays to identify transcription factor dimers that may function in the C. elegans digestive tract. The other stud
Transcription Networks in C. Elegans Organogenesis
Children with asthma may be particularly sensitive to fine particulate matter ( 2.5 m in aerodynamic diameter, PM2.5). The parent grant is investigating the effects of variations in outdoor concentrations of PM2.5 and PM2.5 elemental speciation
Asthma Severity in children and fine particle compostion
This is an ARRA award to R01 EY11379 entitled, 'Functional Organization of Visual Area MT' employed two students for the summer of 2009 and 2010 to participate in a summer research experience.
Functional Organization of Visual Area MT
The long-term objective of this project is to understand the molecular basis for soma-germline interactions that govern germline proliferation and meiotic entry. In humans, sterility can result from insufficient proliferation of germ cells or f
CONTROLS OF ONSET OF MEIOSIS IN C. ELEGANS
DESCRIPTION (provided by applicant): Post-transcriptional regulation has emerged as a potent way to control quantitatively and qualitatively gene expression. The RNase III family of double-stranded RNA endonucleases plays crucial functions in m
THE CONTROL OF GENE EXPRESSION BY EUKARYOTIC RNASE III
Vitamin A is clearly an essential nutrient, but its actions in the body are not clearly understood.  Retinoic acid (RA) is a signaling molecule derived from vitamin A that regulates gene expression, thus providing a powerful mechanism through w
Generation of Retinoid Signals during Development
The mammalian pRb family members are well-established regulators of cell cycle progression, quiescence and differentiation and have also been reported to play roles in genome stability and cellular senescence. Notably, mutations that lead to th
Develomental function of Rb family proteins
This Administrative Supplement is intended to accelerate the pace of discovery of Specific Aim 3 of the parent grant.  A major focus of the parent grant was on the function of a protein, PRC1, which is important to cell cleavage. In the Specifi
Induction of Cell Cleavage by the Mitotic Spindle
The research will make cryo-electron microscopy a technique of choice for atomic-resolution structure determination of large complexes, thus accelerating its potential applications in drug discovery. The requested fund is for hiring a recently
HIGH-RESOLUTION CRYOEM RECONSTRUCTION OF LARGE COMPLEXES
Tracking membrane transport by DEER and TR-WAXS The goal of this project is to understand the molecular mechanism of intestinal glucose and sodium transport. The intestine is responsible for the absorption of dietary carbohydrate and more than
STRUCTURAL CHARACTERIZATION OF THE NA+/GLUCOSE COTRANSPORTER FAMILY
was to investigate the novel hypothesis that Wnt inhibits the degradation of proteins following GSK3 phosphorylations and polyubiquitinylation.
CELL-CELL COMMUNICATION IN XENOPUS DEVELOPMENT
We have conducted experiments as proposed and observed that it is essential to add experiments related to the Cocaine and Amphetamine Related Transcript (CART) so that we can examine the two key anorexigenic peptides. These two anorexigenic pep
PERINATAL METABOLIC AND HORMONAL EFFECTS
The purpose of this supplement is to create new jobs for our current project that will help to accelerate the analysis of our data and accelerate the publication and translation into policy of results from our research.  Our goal in the overall
Health, Poverty and Place: Modeling Inequalities in Accra Using RS and GIS: ARRA Administrative Supplement
Communication between platelet SERT and plasma 5HT:   For the first time, we demonstrate that chronically elevating plasma 5HT in vivo by osmotic minipump in normal C57BL/6J mice results in a loss of surface SERT in platelets and a correspondin
Communication between platelet SERT and plasma 5HT
The long-term goal of our research is to elucidate the cellular and circuit mechanisms of decision making and its executive control. Flexible behavior in humans and animals relies on the brain's ability to accumulate information over time, deli
Recurrent neural circuit basis of time integration and decision making
The purpose of this supplement is to support the research and career development of Emmanuel Ngui, DrPH by deepening his understanding of ethical issues in genetic research, particularly research related to his work examining racial/ethnic disp
Ethics and Safeguards in Psychiatric Research
The purpose of this supplement is to accelerate the tempo of the parent grant while engaging 6 students, including 3 young adults in high school, college or trade school from the New Haven community that have backgrounds similar to that of our
HIV/STD Risk Among Young Expected Fathers: Relationship Attachment and Transition
and provide the summer fellows with in-depth exposure to the entire spectrum of research activities required to implement a planned sub-study which includes micro-arrays and gene expression profiles performed on blood and adipose tissue sample
Genetics, Environment and Weight Gain Posttransplant
The global hypothesis of the parent project is that phasic bursting in vasopressin neurons can be explained largely by the understanding of one potassium current, its modulation by Ca++, and its autoregulation by the dendritically co-released n
Electrophysiological Correlates of Vasopressin Secretion
his is an administrative supplement to a funded project focused on accelerating the pace of genetic association studies of Gilles de la Tourette Syndrome (GTS) in population isolates. It is one of three linked applications (together with NS0400
POPULATION GENETIC MAPPING OF TOURETTE SYNDROME
This is an administrative supplement for our clinical trial entitled, “A Combination Trial of Copaxone Plus Estriol in Relapsing-Remitting Multiple Sclerosis.” The requested funds will accomplish three missions:  1)  Achieve ARRA economic g
A COMBINATION TRIAL OF COPAXONE PLUS ESTRIOL IN RRMS
THE ROLE OF TRAUMATIC BRAIN INJURY STRESS RESPONSE ON EXERCISE THERAPY  1a Award Description Supplement to our active RO1 grant (5R01NS61960-2, PI: Grace Griesbach) entitled 'The role of traumatic brain injury stress response on exercise therap
THE ROLE OF TRAUMATIC BRAIN INJURY STRESS RESPONSE ON EXERCISE THERAPY
This project is designed to facilitate efforts under the parent project to elucidate and manipulate protein N-glycosylation pathways in lepidopteran insect cell systems. These efforts have allowed us to develop important, new, insect-based reco
N-glycosylation mechanism in insect cells
. To facilitate our proposed studies in the parent grant, we plan to recruit two summer student assistants. This supplement application is also intended to provide training and research experiences to the undergraduate students, and may lead th
SERUM PROTEOME ANALYSIS OF ORAL CANCER METASTASIS
The project belongs to the area of neurological disorders, and particularly to the field of epilepsy and its therapy. The proposal examines therapeutic antiepileptic potential of four novel pharmacological and dietary interventions in an animal
VALIDATION OF HIGH-THROUGHPUT SCREENING OF CANDIDATE ANTIEPILEPTOGENIC DRUGS
The overall goal of the SDSU IMSD Program is to increase the number of SDSU underrepresented minority students who will enter Ph.D. programs in the biomedical sciences. Through year-round research training, mentoring and academic and profession
ARRA: San Diego State University Biomedical Research Support Program
Among the consequences of normal aging, one of the most distressing is decline in memory. The associated loss of productivity, physical health, and sense of well-being will create an increasing number of critical economic and public health issu
Effects of aging on memory for source of information
This supplement is requested to develop a version of the existing CBT4CBT program that is applicable to alcohol using individuals, using a web-based format. The CBT4CBT program was developed for drug abusers and in a DVD/CD Rom format, largely
Computer-based training for cognitive behavioral therapy
An administrative supplement is requested for a grant that has two broad research themes: the roles of anion transporter SLC26A6 and related transporters in proximal tubule NaCl transport; and the roles of SLC26A6 and related transporters in me
Roles of SLC26A6 in Renal NaCL transport and prevention of Oxalate Uroltithiasis
Many biomarkers are responsive to oxidative stress and modulating effects of antioxidant dietary supplements, but the disease relevance of these markers is uncertain because of the lack of known functional or mechanistic linkages. We propose th
mtDNA mutation/heteroplasmy: a sensitive functional biomarker of oxidative stress
The main objective of the parent RC-1 grant “Development of a Novel Gastrointestinal Radiomitigator” (AI 078514, 09/01/07 - 02/28/10) was to determine the therapeutic efficacy of octadecenyl thiophosphate (OTP), a novel radiomitigator using
Development of a Novel Gastrointestinal Radiomitigator
Endogenous sphingosine-1-phosphate as a radioprotector of intestinal tissues
The Yale Biomedical Informatics Research Training Program is directed by Prof. Perry L. Miller and is based n the Yale Center for Medical Informatics (YCMI) and many other academic units at Yale, reflecting the diversity of Yale's collaborative
Biomedical Informatics Research Training at Yale
This application requests continued support for the doctoral training program in Dynamic Aspects of Chemical Biology in the Departments of Chemistry, Medicinal Chemistry, Molecular Biosciences, and Pharmaceutical Chemistry at the University of
Training Grant in Dynamic Aspects of Chemical Biology
The joint doctoral program (JDP) in Public Health offered by SDSU's Graduate School of Public Health and the UCSD's School of Medicine is an ideal setting for training future investigators who may bridge the two disciplines: behavioral and biol
ARRA: Transdisciplinary Training for Predoctoral Behavioral Scientists- Supplement
The overall aim of this proposal is the development of deoxynucleoside analogs for the treatment of cancer. This includes studies on the mechanism of action and resistance of novel nucleoside analogs as well as the exploration of novel strategi
Nucleoside Analogs as Anticancer Compounds
One of the biggest challenges moving discovery to clinical intervention is the timely and cost effective launching and completion of clinical research studies and the development of support models to aid clinical research management. The Clinic
Clinical and Translational Science award
Prediabetes, the transition phase between normal glucose tolerance and T2DM, is a crucial time for intervention as the progression to T2DM in children is more rapid than in adults. We have shown that 1 out of every 4-5 obese children seen in th
Safety and Resurfacing MD 404 Alt to Holly Road
BURBANK GLENDALE PASADENA AIRPORT AUTHORITY
Gillespie Field Taxiway Reconstruction: Project will repair two aging taxiways, Alpha and Bravo, including shoulders and taxiway areas at Gillespie Field Airport. Work will include reconstructing selected areas of failed pavement, milling, crac
Gillespie Field Taxiway Reconstruction Project Alpha and Bravo
This project includes the milling and paving of Runway 15-33 along with striping, grooving and the installation of duct bank crossings
Airport Development - Runway pavement rehabilitation
Replacement of a perched culvert on Silver Creek, located in Lake County, MI to restore fish passage and natural flow of sediments to benefit native brook trout.
Ongoing rental of workstations.  Dollar amount reported represents the accumulative amount billed through the end of the quarter of the reporting period.
Office Machinery and Equipment Rental and Leasing
Airport Development - Rehabilitate Runway Lighting - 5/23
Rehabilitate runway 9/27 (approximately 6,500' x 120')
GEORGETOWN-SCOTT COUNTY AIRPORT CORPORATION, THE
Airport Development - Rehabilitate Runway 3-21 Pavement, Widen Runway/Taxiway Fillets
Airport Improvement project to replace and rehabilitate runway and taxiway lighting and associated NAVAIDs.  This project will bring the current airfield lighting system into compliance standards, prevent further failures and increase safety, a
The main runway at Westfield-Barnes Airport, known as Runway 2-20, serves aircraft ranging from small private planes to chartered airliners and military jets.  The pavement on Runway 2-20 is old and is exhibiting signs of distress.  In order
Non primary development projects in state block grant program (Improve Gogebic-Iron County Airport terminal building)
RECOVERY - MXDP961018A - Sr-Const Cover Over Parkng/Uoq - A, MXDP961018B - Sr-Const Cover Over Parkng/Uoq - B, Laughlin AFB, TX
RECOVERY - MXDP101012 - Repair Roof, Air Traffic Control Tower, B309, Laughlin AFB, TX
RECOVERY - MXDP031027 - Remove/Prevent Corrosion, Water Towers-B280,282, Laughlin AFB, TX
Scott AFB Flight Line Fence chain link fence
Re-stripe Parking Lot near Headquarters SFS Building 1845 on Andrews AFB, MD
Repair Asphalt on NAV-AIDS Road Taxiway Sierra South on Andrews AFB, MD
Repair Roof Bldg 91130. Furnish all labor, tools, equipment, materials, facilities, and transportation necessary to repair the roof on building 91130 at Hurlburt Field, FL.
Repair Roofs at Buildings 90002, 90050, 90331, 90121, 90145, 90333, 90503, 90700, 90710. Furnish all labor, tools, equipment, materials, facilities, and transportation necessary to repair the roofs at buildings 90002, 90050, 90331, 90121, 90145
Construct Parking Lot for New Visitors Center
Realign O'Neil Avenue and Install Lights
Repair various O&M HVAC Systems, B108, 325, 330
Phone switch areas, force improvements B129, construct new pavement, asphalt and concrete sidewalks and parking area.
This work consist of furnishing all plant, labor material in performing all operations in connection with the construction, demolition, alteration, and repair of the aircraft alert apron slabs, seals and spall in the airfield pavement.All work
This contract is a quanity of one and the unit is lump sum. The work shall consist of furnishing all plant, labor and material in performing all operations in connection with the work shown in drawings for NKAK09-1109, repair install AALZ AMP 3
Repair Electrical Ventilation Patriot Facility (B462)
REPLACE TAXIWAY LIGHTS @ SOUTH ALPHA FACILITY 1771
Provide all labor, tools, parts, materials, facilites, transportations and supervision for paving repair and/or replacement at Vandenberg AFB, CA. XUMU 03-1031A, Repair Parking Lot @ Rentry VEH FAC 8415
Reconstruction of Post Road, Ft. Russel Way, and Old Glory Road. Expansion of Parking Lot at Building 465.
Maintain Base Pavement Markings - Parking Lots and Roads
Install ground source heat pumps B-1541,1501 & 1560 the principal items of work include, but are not limited to demolishing existing HVAC system at building 1560 and installing new ground source heat pumps
Dock 12 Roof Replacement. To provide labor, equipment and material to replace existing EPDM roofing material with TPO roofing system on Dock 12 at Whiteman AFB.
Upgrade and expand capacity of launch control facility electrical
Install a tot-lot playground near the 90 degree turn in Cedar St in MFH
Install Sump Pumps in 114 Military Housing Units
Provide thirteen 25' by 25' replacement concrete slabs and 1,962.89 square feet of spall repairs to airfield pavemnts.
Installation of Heat Destratification System.
Repair LOX Storage Yard: removal and reconstruction of a protion of existing concrete pavement.  The work entailed pavement removal, grading, providing airfield surface and subsurface drainage systems, Portland cement concrete paving, joint sea
To accomplish the repairs to HVAC Admin Area in building 1517. The repairs on the HVAC system and building shall include replacement of air handlers, oil fired burner, ceiling system, lighting fixtures, ventilation ductwork, and replacement of
Contractor shall provide all management, tools, supplies, equipment, labor, and applicable licenses and permits necessary to ensure that Main Gate House, Building 14, demolition, associated pavements, utility cut and capping, backfilling, soddi
The replacement of the HVAC system in building 1122 basement level.  The repairs on the HVAC system and building shall include replacement of air handler, ventilation ductwork, and correlated electrical service to the entire basement level incl
Furnish all plant, labor, material and equipment necessary to repair and replace inefficient lighting systems per contract modification P00007.
Furnish all labor and materials, equipment and services required to paint the exterior and the interior bays of facility #7026.
Furnish all labor and materials, equipment and services required to paint the exterior building 1476 (Chapel Annex).
Furnish all labor and materials, equipment and services required to paint the exterior of Facility# 1260.
Install smoke detectors and carbon monoxide detectors in 361 family housing units.  The smoke detectors must be on a dedicated circuit and must be interconnected so when one sounds they all will sound.  There are a total of 1535 smoke detectors
Repair HVAC, Multi Fac Heating Ventilation and Air Conditioning, Multiple Buildings.  Furnish plant, labor, materials and equipment necessary.  Replace the boilers and/or heating, ventalation and HVAC.  Install new direct digital controls.  Pro
Replace Roof on Building 799, Luke AFB, AZ.
This is a design build to design backup power to a mission critical building and the construction of the same.  Construction will consist of constructing a concrete pad, generator, ATS and fuel tank installation, block wall work, testing and co
Excavate and replace the force main from Hangar 16
Repair/Line, Sewer line east of Gibson Ave.
Audit for water efficiency, Elemdorf AFB, Alaska
Repair the IRMA roofing system of Bldg 3426 by replacement with an EPDM roofing system. The roof under this contract is the 2nd level roof.
Demolition of existing IRMA roof and replacement with adhered EPDM Roof insulated to R-38.
Repair Vandenburg Road, Hickam Air Force Base, Hawaii; Repair HMA pavement; New pavement striping
Repair 8L Access Road, Hickam Air Force Base, Hawaii; Repair HMA pavement; New pavement striping
Airport Development-Reconstruction of Taxiway Victor from Taxiway Foxtrot to Runway 24-Project 2. This project consisted of replacement of the existing pavement due to prominent distresses, including longitudinal cracking and weathering. The ol
Rehabilitate Taxiway V from Taxiway F to Runway 24-Project 2
The project is for Airport development, specifically, the rehabilitation of the primary runway.  The project will enhance safety, protect the federal investment and increase the useful life of the pavements.
The Screen Machine Pulverize II portble screening plant
Ornamental and Architectural Metal Work Manufacturing
AIRPORT AUTHORITY FOR THE CITY OF GREENVILLE & COUNTY OF PITT
Terminal Building Addition (Lobby/Circulation-3500 sq ft and new Departure Lounge-10,400 sq ft)
Airport Improvements at Klamath Falls Airport consisted of the following: Approximately 800 feet of Taxiway E and 870 feet of Taxiway G were constructed. Both areas included drainage and electrical improvements. The benefits gained from this pr
Phase 2 of the Rehabilitation of Runway 5-23 to maintain the integrity of the pavement life.  Work included pavement rehabilitation, marking, grooving, and shoulder grading.  Phase 2 of the project included the rehabilitation of approximately 1
John Murtha Johnstown-Cambria County Airport
Rehablilitate the most heavily used portion for existing 10,000 foot active runway at Robert Gray Army Airfield, Fort Hood / Killeen, Texas.  This will be accomplished by milling the existing asphalt and replacing the designated area with new F
Rehabilitate parallel taxiway to runway 12/30 to increase and sustain economic activity for the airport and its local community
Rehabilitate parallel taxiway to runway 12/30
Acquire Mobile Aircraft Rescue & Fire Fighting Training Facility
Acquire Mobile Aircraft Rescue and Fire Fighting Training Facility
Airport Development: This ARRA grant provides funds for the reconstruction of the southern 6,200 feet of the 150 feet wide Runway 1C/19C at Washington Dulles International Airport.  This project replaces the original pavement constructed in the
construction of sewer district for Johnson's Corner Sanitary Sewer District--Sussex County, DE
Johnson's Corner Sanitary Sewer District
MBC - I690, TEALL AVE TO I481, CITY OF SYRACUSE, ONON CO
PREDESIGN SERVICES FOR REPLACMENT HVAC & ELECTRICAL/CONTROL SYSTEMS
AIDS International Training and Research Program - ARRA  This award provides funding for a postdoctoral fellow to conduct global health research on the use of HAART for asymptomatic HIV positive women in Lilongwe, Malawi.  The study builds on c
AIDS International Training and Research Program-ARRA
This post-doctoral training project focuses on a child clinical psychologist currently working at the Judge Baker Children's Center, Harvard Medical School. The child clinical psychologist has expertise in the implementation and dissemination o
Development of a PhD Clinical Sciences Program in Vietnam
The long-term objective of the proposed project is to provide the public health (PH) workforce with improved access to high quality, relevant PH grey literature reports in order to positively impact the planning, conducting, and evaluating of P
IMPROVING PUBLIC HEALTH GREY LITERATURE ACCESS FOR THE PUBLIC HEALTH WORKFORCE
OFFICE OF SPONSORED PROGRAMS 113 BOWNE HALL
The purpose of this administrative supplement is to establish a developmental program encompassing the general area of Regenerative Medicine and falling under the umbrella of the theme of our current MSMRCMI grant 'Tissue Protection and Reparat
Enhancement of the Capacity for Biomedical Research (RCMI)
In the present administrative application we are requesting financial support to sponsor summer research experiences for four (4) High School science educators and four (4) High School students.  This administrative supplement will be requested
RCMI Program at the Ponce School of Medicine
Award of grant ARRA funds by CDC will allow the Iowa Immunization Program to provide funding to local public health agencies to sustain or increase the number of children and adolescents currently being seen, increase services such as clinics h
Immunization & VFC - Reaching Children & Adults
These funds will support efforts to plan, develop, and maintain a public health infrastructure to help assure high immunization coverage levels and low incidence of vaccine-preventable diseases.  The program will partner with health department
American Recovery and Reinvestment Act (ARRA) Supplemental funding for Reaching More Children and A
The funds requested for the Immunization and Vaccines for Children Grant will be utilized to increase access to adult vaccines and to build community capacity for immunization services. The Immunization Program will use the vaccine funds to sup
Immunization and Vaccines for Children Grants
317 StimulusFinancial Assistance Funding to ODH Immunization Program  Purpose: Funds are available from the 2009 American Recovery and Reinvestment Act for Financial Assistance to current Section 317 immunization grantees. The goal for the use
Supplemental Funding for Immunizing More Children and Adults
ARRA Supplemental Funding for Reaching More Children and Adults will support the operations infrastructure needed to deliver vaccine and account for individuals vaccinated with supplemental vaccine funding. The focus of activities supported wit
American Recovery and Reinvestment Act (ARRA) Program Operations funds awarded to the State of Utah Department of Health Immunization Program was contracted to local health departments (LHDs), TriSano, KIPHS, Inc. and Custom Data Processing (CD
Supplemental funding for reaching more children and adults in the community to ensure access to proper preventative health care.  The CNMI Immunization Program?s plan includes three elements: increasing the proportion of young children who rece
The following components are identified and proposed for utilization of the Hawaii allocation of the ARRA supplemental operational funds for immunization to support the 2009-2010 and 2010-2011 statewide school-based flu vaccination program, the
ARRA - 317 Immunization and Vaccines for Children Grants
Funds are available from the 2009 American Recovery and Reinvestment Act for Financial Assistance to current Section 317 immunization program grantees.  The purpose of this funding opportunity is to enable Section 317 grantees to develop the ca
ARRA-317 Immunization and Vaccines for Children Grants-1
The development of alcoholism related traits is believed to be caused by both genetic and environmental factors, in addition to their interactions. Genetic variations associated with alcoholism related traits can affect several different mechan
Genomic regulatory sequence analysis for alcohol-related phenotypes
This is a supplement to the K01 Regulation of Prostate Cancer Growth by PPARg ligands grant. This supplement will advance knowledge on how agonists for peroxisome proliferator activated receptor gamma proteins reduces the growth of prostate can
Regulation of prostate cancer growth by PPARg ligands
My ultimate objective is to conduct effective, independent research in cancer prevention and control, focusing on behavioral science applications for underserved populations, beginning with studying Hispanic cancer survivors. Specifically, I wi
DETERMINANTS OF EXERCISE ADHERENCE FOR HISPANIC CANCER SURVIVOR
Cryptosporidiosis is an opportunistic infection caused by Cryptosporidium parvum or C. hominis in humans. We propose to study the role of key antigen presenting cells and dendritic cells in stimulating anti-parasite immunity in cryptosporidiosi
The role of Dendritic cells in T cell immunity to Cryptosporidium
The purpose of this study is to compare 5 to 12 year old siblings who are discordant in their weight status (i.e., normal weight or overweight obese) on select eating traits both under laboratory and free living conditions.  We are requesting a
Eating Behaviors Among Weight-Discordant Siblings
In the spirit of the American Recovery and Reinvestment Act (ARRA) of 2009, this supplemental award aims to create a job for a research technician who will accelerate the tempo of research of the parent grant (1 K01 DK080194-01).  The parent gr
AN EPITHELIAL MODEL FOR V-TYPE H+-ATPASE-DRIVEN ACID BASE TRANSPORT
Because trials to compare digital and analog mammography rely on complex designs, cost large amounts of money and involve the health of many women, accurate power and sample size calculations are essential. In these trials, radiologists read ma
Power and Sample Size Methods for Mammography Trials
Colon Cancer Screening Decisions in Late Life - ARRA  With the requested funds, we will be able to increase the value of the parent grant’s findings by conducting additional analyses of unexpected findings from the parent grant and feeding th
Colon Cancer Screening Decisions in Late Life - ARRA
Risk factors for site-specific metastasis in esophageal cancer are poorly understood.  As part of my current K07 award, we are currently enrolling patients to assemble a cohort of study subjects with newly diagnosed esophageal cancer.  Based on
Risk factors for site-specific metastasis in esophageal cancer
Dr. Yu-Ning Wong, a Medical Oncologist at Fox Chase Cancer Center is dedicated to a career in cancer health services research. Her goal is to develop a multidisciplinary research program to understand the impact of insurance design on cancer dr
CLINICAL AND SOCIAL IMPLICATIONS OF COST SHARING FOR CANCER DRUGS
HIV-1 infection is associated with loss of CD4+ T cells, chronic immune activation and progressive immune dysfunction. HIV-specific responses, particularly those of CD4+ T cells, become impaired early after infection and the basis for this decl
T cell regulation: CD4+CD25+ FOXP3+ T cells in acute and chronic HIV-1 infection
The PI of this grant is an M.D., Ph.D. who is committed to academic research and recently completed his clinical training in the Division of Infectious Disease  at the University of Washington in Seattle. The proposal describes a 5 year trainin
The Role of Nod1 and Nod2 in the Pathogenisis of Legionella Pneumophila Pneumonia
This proposal describes a five year career development plan for Soumya Raychaudhuri in statistical genetics. Dr. Raychaudhuri is a Rheumatology fellow at the Brigham and Women's Hospital (BWH). He will integrate his background in bioinformatics
Bioinformatics and Population Genetics to Identify Rheumatoid Arthritis Genes
The proposed project will be performed in the areas of tyrosine kinases, cytoskeleton, and invasion/metastasis in SCLC. My long term career goal is to become an independent clinician-scientist in translational cancer research with focus on targ
Studies of Alrernations of C-MET in SCLC
This application requests an administrative supplement for a mentored K-award (K08-CA128565) in accordance with the stated goals of the American Recovery and Reinvestment Act of 2009 (ARRA).   The purpose of this administrative supplement will
Investigation of the Wnt/PCP pathway in human malignant melanoma
The goal of the proposed research is to characterize novel isoenzyme-selective inhibitors of histone deacetylase 6 (HDAC6) to enable human clinical investigation. Following proteasome inhibition, perinuclear aggregates of insoluble ubiquitinate
Selective Inhibition of HDAC6 in Cancer Therapy
domain 3 in in vivo systems including a JFH-based system that produces actual viral particles.  Clearly, our proposal for use of these supplemental funds will accelerate our progress significantly and position us better for compiling a more co
THE PATHOGENESIS OF STEATOSIS IN HEPATITIS C GENOTYPE 3 INFECTION
With the increased use of prenatal screening by ultrasound, more fetuses are being diagnosed as potentially having congenital renal obstruction (2-5% of all pregnancies in the US). To date, the most common cause of renal failure in children is
The effect of congenital renal obstruction of the urinary proteome in infants
Matrilysin regulation in colonic epithel
The supplement was intended to accelerate the pace of the parent grant K08MH079088 and as a result to retain the new PI in the workforce.  A new position for a trainee was also proposed.  We have created a position for a research technician and
The contribution of adult-born neurons to hippocampal structure and connectivity
Purpose: to enhance our understanding of human visual processing and perception.  Abstract: The ability to identify and discriminate an endless array of visual objects is a challenge to even the most powerful computers, yet humans can rapidly m
Washington University is fortunate to have an outstanding vision research community complementing a largeand busy clinical service. This combination of research and clinical resources make the University anexcellent institution for the training
PHYSICIAN RESEARCHERS IN OPHTHALMIC SCIENCES
Until the present, PERT trainees have had outstanding success in obtaining tenure-track positions at R1 Universities, and the program itself has had a greater number of such placements than comparison groups at the University of Arizona.  Howev
Post Doctoral Excellence in Research and Teaching
Many human disorders such as cancer come about because genes are not regulated properly.  One way genes are controlled is by how they are packaged.  New drugs are needed to specifically alter the packaging of cancer genes.  We have identified o
Characterization of Small Molecule Inhibitors of HDACs and DNMTs - ARRA Stimulus Admin Suppl #1
Hepatitis C virus (HCV) is a leading cause of liver cancer worldwide. During infection, HCV induces the formation of rearranged membrane structures termed web. These membranes are also observed in vitro following expression of HCV NS4B protein
HEPATITIS C VIRUS REPLICATION AND INTRACELLULAR MEMBRANE REARRANGEMENT
'The purpose of this grant is to determine the effect of HAART on HPV infection and HPV-related anal dysplasia in HIV-infected individuals.Abstract: HIV-infected individuals have improved survival in the highly active antiretroviral therapy (HA
The Epidemiologic Effects of HAART on HIV-related Anal Cancer and Anal Dysplasia
The research projects focus on the interrelationships between age-related changes in auditory and cognitive function and their contributions to changes in communication abilities of older adults. Knowledge of the auditory and cognitive factors
Auditory Temporal Processing in the Aging Ear and Brain
ESCRIPTION (provided by applicant): Amyotrophic Lateral Sclerosis (ALS) is an untreatable neurodegenerative disorder characterized by progressive loss of motor neuron function. Respiratory failure is the most common cause of ALS patient death.
Pilot Placebo-Controlled Trial of Early Noninvasive Ventilation for ALS
The aim of this administrative request is to preserve a unique research resource, enhancing the follow-up participation of the clinical study, the Tennessee Children’s Respiratory Initiative, and increasing the capacity for data analysis. The
MidCareer Investigator Patient-Oriented Research Award in Bronchiolitis & Asthma
This administrative supplement builds on the applicant's current K-24 award.  Specifically, the third component of the program project outlined in the original K-24 award focused on utilizing clinical/radiologic findings from patients presentin
K24 Mid-Career Investigator Award in Patient-Oriented Research
) applications to provide service delivery to trauma survivors, in order to address disparities in rural resource utilization. His long-term goal is to continue to develop a unique expertise in the area of mental health services and economic re
Mentoring/Carrer Development in PTSD Services Research (ARRA)
This supplement is requested to accelerate the pace of research described in the parent application K25CA120350. The overall goal of that project is the development of a novel class of near infrared agents for applications in diagnostic imaging
A NEAR-INFRARED CONTRAST AGENT FOR TARGETED IMAGING OF CANCER
The objective of our research is to investigate the functional contributions of chemokine signaling interactions with TGF-beta signaling in the breast cancer microenvironment using biochemical, molecular biology, cell biology approaches and who
Functions of chemokine and TGF-B signaling in the breast cancer microenvironment
Cancer and congenital malformations occasionally may have a common etiology. We have recently demonstrated that cleft families present a higher incidence of family history of cancer and that AXIN2, a gene that when mutated increases susceptibil
Clefts/Craniofacial Anomalies and Cancer Susceptibility
Autoimmune Type 1 Diabetes (T1D) results from autoimmune destruction of insulin-producing pancreatic beta cells.  The overall goal of this proposal is to further determine how the defects in immunological tolerance induction underlying T1D in t
ROLE OF THE INKT-DENDRITIC CELL AXIS IN TYPE 1 DIABETES IN NOD MICE
In the parent grant, we hypothesized that pro-oxidant pesticides inducing similar clinical manifestations - rotenone and paraquat - will have different initial sites of action. Therefore, in the precocious phases of intoxication, they will caus
Oxidative Modification of Brain Proteins in Pesticide Intoxication
Polycythemia vera (PV) is a human disease where too many red blood cells are produced.  Current treatment for PV is inadequate due to blood clotting problems abd development of leukemia.  In this proposal, a mouse model of PV will be used to be
Molecular Pathogenesis & Therapy in JAK2 V617F Myeloproliferative Disease
Repair/Upgrade Communications Infrastructure, Kuntz Ave.
Install Traffic Signal at Vandenberg and Freedom
This project involves the complete rehabilitation of the perimeter roadway and service aprons between the East Ramp and Hangars 1, 3, 5, 7 and 9 (Buildings 7087, 7075, 7073, 7072 and 7071) and which extends at a width of approximately 24 feet n
Sustain Munitions Rd from Alert Rd to SE 59th St.
ROOFING REPAIRS - REROOF BLDG 1066 COMMAND POST.
Install Electrical Power Poles in Bldg. 280
Nonpersonal services to include all parts, labor, equipment, materials and transportation for HVAC Duct Cleaning and Mold Decontamination for Bldg 301 Headhouse & Main Floor.
Non personal services to include all parts, labor, equipment, materials, and transportation, for HVAC Duct Cleaning and Mold Decontamination for Bldg 300, Bay C and D.
RECOVERY - AMPI: In-Line Tow Coating for Silicon Carbide (SiC) Fibers  Ceramic Matrix Composites (CMCs) will replace metal coated components resulting in a decrease in specific fuel consumption (SFC) for turbine engines.   Program generates imp
Research will be conducted, studies will be performed, and support will be provided for various alternative energy programs to include: 1.  Support research efforts on alternative aviation fuels including production, technical analysis, life cy
Overall Statement of Work: Boeing will assist the US Air Force in determining the best possible configurations for its future mobility fleet of aircraft by investigating the design and performance of revolutionary aircraft configurations, desig
Advanced Manufacturing Techniques for Large Area Solid Oxide Fuel Cells and Energy Applications
The Air Force has identified improved fuel burn as an important metric for gas turbine engine technology development programs.  The purpose of this task order is to perform system level engine cycle studies to assess the impact of a broad range
'Efficient Small Scale Propulsion Core Engine Demonstrator Design and Risk Reduction (ESSP)'  This contract covers the conceptual and preliminary design of an advanced small core engine that can be used as the basis for a turboprop, turboshaft,
Resurface Wattendorf Phase 2 In accordance with Rogers Group proposal dated 27 Apr 09 and Statement of Work dated 14 Sep 07.
Paint roof top equipment Marble Cream.  Install prefinished (Redwood) rain gutters and downspouts to replace all existing gutters and downspouts.  Replace splasg blocks.  Install walkpads to equipment from roof hatch.This facility is located
This facility is located at Edwards Air Force Base, California.
dense deck and single-ply roofing system.  Replace metal flashings, drip edges and roof drains.  Install walkpads to equipment from roof access.  This facility is located at Edwards Air Force Base, California.
Life Safety, Install emergency generator capable of supplying full capacity to the facility.
Cameron Missouri State Veterans Home Emergency Generator Replacement
Mexico Missouri State Veterans Home Emergency Generator Replacement
VETERANS AFFAIRS, NORTH CAROLINA DIVISION OF
Construction of a 100-bed State Veterans Home
Construction of a 100-bed State Veterans Home.
S COOS RIVER RD: ANSON ROGERS BRDG REPAIR
PAVEMENT OVERLAY ACCORDING TO 1R GUIDELINES AND SIGNAL INSTALLATION
WASHBURN WAY: CROSBY-JOE WRIGHT RD PAVING (KFALLS)
IMPLEMENT LAND USE & TRANSPORTATION MODELING SYSTEM FOR REGIONAL TRANSPORTATION PLANNING
REGIONAL TRANSPORTATION-LAND USE MODELING SYSTEM
INSTALL SIGNS AND SIGNALS, GUARDRAIL REPAIR
NW CORNELIUS PASS RD SAFETY IMPROVEMENTS
UPGRADE BRIDGE GUARDRAILS AT VARIOUS LOCATIONS
FLASHING YELLOW ARROWS & ILLUM SIGN REPLACEMENT
A. Scope of Work Design, build, and test a 3-phase transmission-class (> 100 kV working voltage) and build, test and demonstrate in the electrical grid. Task 1: Complete Design, Build and Qualify a Single-Phase of the Compact Transmission-Volta
Design, Test & Demonstration of Saturable Reactor High-Temperature Superconducting Fault Current Limiters
Electric Bulk Power Transmission and Control
STATE OF IDAHO MILITARY DIVISION - INWBAUB-IDARNG-Payette Armory
Heating Equipment (except Warm Air Furnaces) Manufacturing
COUNTY OF FORT BEND - SSS-Fort Bend County Sheriffs Office-Access Control
STATE OF IDAHO MILITARY DIVISION - INWBAUB-IDARNG-Rigby Armory
Ceiling insualtion is being added to all units.  All faucets, showerheads and toilets are being replaced with water savings energy devices.  Ceiling fans and programmable thermostats are being added to each unit.
Energy saving HVAC units will be placed in 10 units.  water savings devices will be used for all faucets, toilets and showerheads.  Ceiling fanx and programmable thermostats will be placed in all units.
New Windows Porch Railings Fencing around Maintenance Replace Damaged Driveways and sidewalks
ARRA Capital Fund Public Housing Grant for the modernization of the Palm Beach County Housing Authority. This funding is expected to result in providing employment for engineers, construction workers and product manufacturers. In addition, this
Capital Fund Program assistance to carry out capital and management activities to serve low-income families.  Funds will be used specifically for site acquisition, predevelopment costs and administration for a mixed use office building containi
Conduct modernization activities at vaious Public Housing developments.  This funding can be expected to result in providing employment for architects and engineers, construction workers and product manufacturers.  In addition this funding can
NORTH WEST FLORIDA REGIONAL HOUSING AUTHORITY
American Recovery and Reinvestment Act  Funds made possible the Replacement of Windows, Interior Doors and Kitchen Cabinets; and Upgrade of Bathrooms and Electrical Systems in Public Housing Dwelling Units.
HOUSING AUTHORITY OF THE CITY OF NEW SMYRNA BEACH
HOUSING AUTHORITY OF THE THE CITY OF LIVE OAK
Conduct electrical modernization activities to 104 units and provide handicapped accessibility to 6 units. This funding can be expected to result in providing employment for architects and engineers, construction workers and product manufacture
Public Housing Capital Fund Stimulas (Formula) Recovery Act Funded
Replacement of windows in public housing with energy efficient windows.
Public Housing Capital Fund Stimuls (Formula) Recovery Act Funded
TO REBUILD PUBLIC HOUSING UNITS DEMOLISHED WITH RELOCATION/DEMOLITIOON FUNDING
Project summary: The long-term goal of the proposed research is to understand the molecular mechanisms of synaptic plasticity. Heterotrimeric G proteins have been implicated as regulators of synaptic plasticity in various organisms, but the mec
REGULATION OF SYNAPTIC TRANSMISSION BY GQ
There are currently over 250,000 survivors of childhood cancer in the U.S. Recent diagnostic therapeutic advances in pediatric oncology have led to greater survival rates in children and young adults with malignancies. However, while cancer the
Measures of Fertility in Young Cancer Patients
These Administrative funds help food banks distribute the additional $1,838,165 of commodities awarded through ARRA.
ARRA - WIC System - To provide grants to WIC State agencies for Electronic Benefit Transfer projects and pilots to explore the feasability both technical and financial of providing WIC benefits electronically.
The goal of The Emergency Food Assistance Program (TEFAP) is to increase the amount of food that is being distributed throughout the State of Nebraska.  The money is being spent on warehousing and freight expenses moving the food through the ex
The Emergency Food Assistance Program (TEFAP) Administrative Funding
The purpose of this award is to establish a conditional GDNF knockout mouse colony at MUSC which will substantially expand and accelerate the current research associated with the aims of the parent grant PO1 AG023630.
Dual-Hit Hypothesis for Aging Related DA Dysfunction - Administrative Supplement
DNA Damage and Neurodegeneration in the Aging Brain. The supplement will satisfy the main goals of the Recovery Act by employing a researcher and accelerating new research with the potential to uncover new insights into mechanisms of and treatm
DNA Damage and Neurodegeneration in the Aging Brain
Most HIV transmissions occur mucosally, including mother-to-child transmission (MTCT). As HIV clade C predominates worldwide, we initially focused on immunoprevention of HIV clade C MTCT. We identified a quadruple (4x) combination of human neut
Vaccination against mucosal HIV clade C transmission
This is an administrative supplement request to support research in our Program Project grant P01-CA16519, Molecular and Cellular Basis of Tumorigenesis. This administrative supplement request represents an opportunity to increase the tempo of
PROGRAM ON MOLECULAR AND CELLULAR MECHANISMS OF TUMORIGENESIS
The funds requested were for (a) additional supplies to expand high throughput sequencing of RNA populations, (b) to purchase an essential instrument for quantization of images and (c) to support the extension of a postdoctoral appointment for
Characterization of Pathways Controlling Cancer at the Level of Gene Regulation
Large prospective studies of diet and cancer have often not supported hypotheses that were based on animal and ecological findings; one possible explanation could be large measurement errors in the assessment of diet. Thus, the National Cancer
Prospective Studies of Diet and Cancer in Men and Women
, is to develop novel therapies targeting host-tumor cell interactions to overcome drug resistance and achieve long-term disease free survival and potential cure of MM. This Program builds upon and extends progress during the prior funding peri
Host-Tumor Cell Interactions in Myeloma: Therapeutic Applications
This is supplemental funding request for a multidisciplinary combined modality program project grant with two major clinical protocols, both dealing with the use of photodynamic therapy (PDT), one for intraperitoneal carcinomatosis and the othe
Photodynamic Therapy for Neoplastic Diseases Involving Serosal Surfaces
The incidence of thyroid cancer is rising at the second fastest rate of all malignancies in the United States and has an increasing tumor-specific mortality annually, making it an important public health problem. The reasons for this increasing
(ARRA) Genetic and signaling pathways in epithelial thyroid cancer
Project 1 – This project examines the role of Na+/H+ exchangers (NHE) in diarrhea associated with infection by enteropathogenic E. coli (EPEC). EPEC inhibition of NHE3 may contribute to the pathophysiology of associated diarrhea. EPEC, howev
Nephrolithiasis is a common, costly and recurrent condition, but there is sparse information on the influence of genetic factors and gene-environment interactions. The overall long-term objective of this Program Project is to expand our knowled
Regulatory Networks in Human Embryonic Stem Cells
We received an administrative supplement with ARRA funding to support a summer outreach research and training program.  The supplement provided for opportunities for high school students, undergraduate students, and a high school teacher to imm
Signaling Hierarchies in Vertebrate Development
The project shall provide unique and fundamental data about the emergence of cognitive competence, for instance by yielding a comparison between multiple primate species on tasks for which a single species has already been tested. The project w
Brain, Behavior and Emergence of Cognitive Competence
, has the main goal of understanding the nature of changes in neocortical excitatory circuits in the freeze lesion model of focal cortical dysplasia with relevance to epilepsy. In the course of addressing aim 2 of the parent grant with the meth
Our preliminary data demonstrate that treatment of aged ischemic rats with sildenafil substantially enhances neurogenesis and improves functional outcomes, although neurogenesis in the SVZ is impaired in aged ischemic animals. These data indica
The purpose of the funding is to increase enrollment in a clinical trial of erythropoietin in TBI patients (Projects 1 and 2), and to purchase equipment for Project 3.  Projects 1 and 2 of our grant are a clinical trial of 200 severe TI patient
Vascular Mechanisms of Secondary Injury after TBI
Alexander disease is a rare and typically fatal neurodegenerative disease that results from heterozygous mutations in the gene encoding the type III intermediate filament protein GFAP. The pathological signature of the disorder is the Rosenthal
ARRA Supplement - Alexander Disease: Cellular and Molecular Mechanisms
The new personnel continue to be involved in Project 2 by performing TBI in swine, performing MRI and biomarker data collection and performing extensive histopathological analyses. They will interface with the other projects and cores of the Pr
Mild Traumatic Brain Injury and Diffuse Axonal Injury
This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represe
Mechanisms of plasticity and repair after SCI
The Nebraska Center for Virology (NCV) is making tremendous strides toward achieving its goal of becoming a Center of Biomedical Research Excellence in Virology. One way it is doing this is through support of five thematically-linked research p
The goals of the COBRE Neuroscience Supplement 3P20 RR016435-09S2 are specifically directed to further strengthen the neuroscience research infrastructure at  the University of Vermont by three mechanisms: (a) supporting technical positions in
The Maine IDeA Network of Biomedical Research Excellence (ME-INBRE) in Comparative Functional Genomics is led by the Mount Desert Island Biological Laboratory and is composed of two research institutions, one graduate degree granting institutio
Comparative Functional Genomics INBRE in Maine
The Kansas IDeA Network of Biomedical Research Excellence (K-INBRE, first known as the K-BRIN) was established in 2001 as a network of 9 Kansas institutions of higher learning. Kansas falls into the bottom half of states receiving research fund
Kansas IDeA Network of Biomedical Research Excellence
The purpose of this supplement is to establish new infrastructure in the Center for Oral Health Research (COHR) to address translational oral cancers needs at MUSC; and provide additional staff in the COHR to initiate oral cancer support-relate
SC COBRE for Oral Health Research: ARRA Admin Supplement to Advance Translational (T1&T2) Research
CENTER FOR COLON CANCER RESEARCH The long-term goal of this study is to leverage our combined experience in nanotechnology, cancer biology and stem cell biology to develop novel strategies for understanding cancer stem cells (CSCs). CSCs are th
ARRA funds will be used to launch two pilot projects that involve nearly all COBRE faculty to foster collaborations.  We specifically plan to obtain critical new information regarding the interaction of microorganisms that we study with two ear
T cell based therapies for cancer in the form of adoptive T cell transfer (ACT) or cancer vaccines can kill tumors expressing immunodominant tumor antigens. However, this process allows the escape of tumor cells expressing poorly immunogenic o
MENTORING TRANSLATIONAL RESEARCHERS IN LOUISIANA
The overall goal of this supplement proposal is to advance the aims and goals of the present Center of Biomedical Research Excellence (COBRE) P20 RR15557 (PI: Irvin) program is to create a sustainable center of research excellence in Lung Biolo
Advancing the Application of Medicare Claims Records for Health Care Research       The goal of this supplement is to accelerate the development of researcher-friendly database resources that are constructed from Medicare claims records.  The f
NBER Center for Aging and Health Research-Medicare Claims Records
DESCRIPTION (provided by applicant): This is an application to continue the Michigan Center for Urban African American Aging Research (MCUAAAR) at the University of Michigan and Wayne State University. Conceptually, the research and training ac
MICHIGAN CENTER FOR URBAN AFRICAN AMERICAN AGING
The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins has been participating in the planning activities associated with the project entitled ADOPTion of New Technologies for Remote Data Capture and Protocol Authoring by providing appro
This award is issued in response to Notice OD-09-060, Recovery Act Administrative Supplements Providing Summer Research Experiences for Students and Science Educators. DESCRIPTION (provided by applicant): Memorial Sloan-Kettering Cancer Center
The UAB Comprehensive Cancer Center is requesting equipment to support a new caBIG compatible Clinical Trials Management System (CTMS). The equipment requested is manufactured by companies, Dell Inc. and Buffalo Technologies Inc., with U.S. hea
RPCI is committed to focusing clinical research resources on processes that will improve the efficiency and effectiveness of study implementation, participant accrual and study data collection with an emphasis on investigator-initiated studies
Roswell Park Cancer Institute Center Support Grant
The Ohio State University Comprehensive Cancer Center (OSUCCC) is currently in its 29th year as an NCI-designated CCC and is now requesting continued federal support for the next five years. The OSUCCC named its 4th Director, Michael A. Caligiu
(ARRA) The Ohio State University Comprehensive Cancer Center
Cell migration and invasion are critical to cancer progressiona nd metastasis, and a better understanding the mechanism and regulation of these processes could suggest new approaches for controlling cancer.  Missing in Metastasis (MIM) is an ac
The OHSU Knight Cancer Institute (Knight) has a history of running high-impact Phase I clinical trials, including imatinib, calcitriol and most recently MDV-3100.  As part of the Phase I studies, Knight investigators have developed pharmacodyna
The Cancer Research Center of Hawaii (CRCH) is an NCI-designated Clinical Cancer Center. CRCH has diverse responsibility in cancer research, education, community outreach, and patient care. It is the only such institution in the State of Hawaii
The Alvin J. Siteman Cancer Center (SCC) at Washington University School of Medicine and Barnes-Jewish Hospital received NCI designation as a Clinical Cancer Center in 2001, and as a Comprehensive Cancer Center in 2004. The SCC is composed of e
The mission of the University of Maryland Marlene and Stewart Greenebaum Cancer Center is to undertake innovative basic and clinical research which will impact the understanding and treatment of cancer around the world and to provide state-of-t
University of Maryland Greenebaum Cancer Center Support - Administrative Supplement
ADOPTion of New Technologies for Remote Data Capture and Protocol Authoring (ADOPT)  The NCI has made significant progress in reconfiguring the NCI trials infrastructure to allow investigators to take full advantage of scientific opportunities.
This Administrative Supplement Award will be used to recruit a newly-independent, tenure track physician- scientist at the Assistant Professor level to the Moffitt Cancer Center (MCC).  As required by the supplement, this person will be a labor
The purpose of this supplement grant is to provide funds for equipment purchases for the Core Laboratories of the NY Obesity Nutrition Research Center and to increase the funding for the Pilot and Feasibility Program.  The P/F Program is now aw
The major goal of the Clinical Nutrition Research Unit (CNRU) at the University of Washington is to promote and enhance interdisciplinary nutrition research by bringing together basic science and clinical investigators on a cooperative basis. T
This administrative supplement supports the Center's ongoing programs and Core as follows: A) Pilot and Feasibility Program (Administrative Core: Lee M. Kpaln, MD, PhD, Associate Director): These supplemental funds enable the Center to accompli
This application is for a 5 year renewal of the Colorado Clinical Nutrition Research Unit (CNRU). The Colorado CNRU was originally funded in January, 1995 to serve 41 investigators. Now, in our eleventh year of operation, we serve 67 investigat
Colorado Clinical Nutrition Research Unit
The University of Southern California Research Center for Liver Diseases, funded since 1995, has the goal of fostering and facilitating interdisciplinary research in liver and digestive disease. The Center has 41 members and 17 affiliated membe
The mission ofthe Minnesota Obesity Center is to find ways to prevent weight gain, and the onset of obesity and complications of obesity. Obesity is a major source of illness and death, and is the most common nutritional ailment in the United S
The development of effective gene therapies for inherited disorders requires interdisciplinary programs that focus on the identification of disease genes, an elucidation of disease pathogenesis, and the development of technologies for genetic m
Center for Gene Therapy of Cystic Fibrosis and Other Genetic Diseases
This application seeks continued funding for the Washington University CNRU. Since our CNRU was originally funded in 1999, it has served as a nidus for the growth and development of nutrition research at Washington University. The research infr
WASHINGTON UNIVERSITY  CLINICAL NUTRITION RESEARCH UNIT
Title: Generation of Novel AAV Variants by Directed Evolution for Improved CFTR Delivery to Airway Epithelium In Vitro and In Vivo. This project is to generate novel adeno-associated virus (AAV) vectors through an in intro evolution technique b
Molecular Therapy Core Center - ARRA Supplement
an endogenous mediator-based therapeutic strategy for treating the chronic and severe inflammatory episodes experienced by CF patients.
Basic and Clinical Studies of Cystic Fibrosis
'The overall goal of the DERC is to promote diabetes research in clinical metabolism and nutrition.  Scope of the Overall Project: This Diabetes Endocrinology Research Center (DERC) application was submitted under a P30 grant mechanism in respo
Diabetes & Endocrinology Research Center (DERC)
This Center grant requests funding for seven Core facilities to support a broadly-based research program in the study of mental retardation and developmental disabilities. The seven Core facilities are: Administrative, Proteomics, Cellular Neur
Mental Retardation and Developmental Disabilities Research Centers 2006
This grant provided a summer research experience for 9 high school students and one science educator in health-related scientific research. All participants were affiliated with Gregorio Luperon High School, a Mathematics and Science High Schoo
Center for Evidence-based Practice in the Underserved (CEBP)
This is to continue NINDS funding of a Core Facility at Brandeis University. This will allow us to fully exploit the three subcomponents that are now firmly established: a microarray and FACS facility, an imaging facility and a mouse/transgenic
Core Facilities for Neurobiology at Brandeis
The California sea hare, Aplysia californica, is a large marine snail with a very simple nervous system. The National Resource for Aplysia, located at the Rosenstiel School of Marine and Atmospheric Science of the University of Miami, raises an
PEROMYSCUS LABORATORY MODELS FOR BIOMEDICAL RESEARCH The Peromyscus Genetic Stock Center (PGSC) provides disease-free peromyscines to researchers worldwide, and promotes the use of Peromyscus through development of genomic, reproductive,preserv
PEROMYSCUS LABORATORY MODELS FOR BIOMEDICAL RESEARCH
This application proposes the acquisition of resources (personnel and equipment) that will enhance and accelerate the translational activities conducted in two NCRR-supported Animal and Biological Materials Resources (ABMR): 1) the Vervet Resea
Vervet Research Colony as a Biomedical Resource
These supplemental funds will create a yeast modENCODE-like database to enhance the SGD budding yeast resource, enhance the analysis of modENCODE data, facilitate the advancement of science with the incorporation of yeast systematic results int
Genomic Database for the Yeast Saccharomyces
The primary goals of the proposed supplementary effort are two-fold and concern accelerating the pace of research within the scope of the parent award LM-7085 (P41). First, we will accelerate the pace of work to directly address the issues that
Subproject for Institution # 06-000724: Center for Critical Assessment of Structure Prediction
Title: Development of Medical Biophotonic Technologies for Imaging and Therapy. This administrative supplement to the Laser Microbeam and Medical Program (LAMMP P41RR01192) supports LAMMP core 3, Virtual Photonic Technologies (VPT). Specificall
A Laser Microbeam Biotechnology Resource
Title: Development of Bedside Medical Biophotonic Diagnostic Devices. This administrative supplement to the Laser Microbeam and Medical Program (LAMMP P41RR01192) supports  LAMMP core 2, Medical Translational Technologies (MTT). Specifically, w
We propose to establish the 'Center for Integrative Biomedical Computing' and, through its work, to address important biomedical research problems in bioelectric fields, imaged-based anatomy, multi-scale tissue modeling and simulation, and scie
CENTER FOR INTEGRATIVE BIOMEDICAL COMPUTING
The Neuroimage Analysis Center (NAC), a national resource center, is developing algorithms and image analysis software tools for improving our understanding of brain diseases and enabling innovative treatments. The focus of this competitive ren
Neuroimaging Analysis Center: Image Analysis for Personalized Medicine
In this application we seek renewed support for our continued efforts to develop innovative neuroimaging technologies within the highly integrated multimodal framework of our P41 Regional Resource, the Center for Functional Neuroimaging Technol
Center for Functional Imaging Technologies
Biomarkers of Exposure to Hazardous Substances Administrative Supplement to Project 3 and collaborating with investigators at the Superfund program at UC San Diego.  This project will develop sensitive tools to monitor the contamination of wide
Subproject for Institution # 870655: BIOMARKERS OF EXPOSURE TO HAZARDOUS SUBSTANCES SUPERFUND BASIC RESEARCH PROGRAM
?Combining Genomic Data From Model Organisms to Provide Insight into Mode of Action?This award is a collaborative project between two laboratories.  Each group is fundamentally focused on understanding the molecular mode of action of toxic chem
Invest the 2009 ARRA Formula allocation of $2,492,107 to purchase one 1 locomotive to replace locomotive # 801.  The original locomotives were manufactured in the mid 1960's and were manufactured in the mid 1960's and were last remanufactured i
Water project (grant & loan): Construction of a stand-alone water plant, wells and distribution lines to service approximately 421 (as of 2004) additional residences providing additional income for the municipal water system and improving healt
Stonemill Creek Water System Improvements
Invest the 2009 ARRA Formula allocation of $13,431,438 to purchase up to 4 locomotives to replace locomotives # 802,803,804 and 805.  The original locomotives were manufactured in the mid 1960's and were manufactured in the mid 1960's and were
Invest in public transportation by constructing a new transit administration and bus parking facility. Ten percent of the award was utilized to fund transit operating.
Transit Vehicles, Preventive Maintenance, Surveillance equipment to enhance the operations and functionality of Transit Property in Ocala, FL, SunTran.
Purchase of a fire truck, emergency response vehicles and related legal services for the City of Marianna Fire Department.  The benefit derived will decrease response time and ensure maneuverability in areas where large pumper trucks are unable
ADD IN RE ALIGNMENT IN ORIGINAL DESIGN&#59; HIGHWAY RELAIGNMENT
US20: PIONEER MTN LOOP RD - YAQUINA RIVER
WASTEWATER TREATMENT, PAVING, ADA UPGRADES, AND RESTROOM REPLACEMENT
RAIL SERVICE IMPROVEMENTS (PORT OF MORROW)
STRIPE VARIOUS HIGHWAYS THROUGHOUT SOUTHERN  OREGON TO ENSURE SAFETY
US101: 12TH ST (TILLAMOOK) - FARMER CR RD
US 20/OR 34: NEWTON CREEK - JADE PLACE (PHILOMATH)
ARRA Botetourt I-81 Undersealing/Paving/Guardrail Upgrades
ARRA Prince Edward 460 Restoration/Lane Extensions/Guardrail
ARRA SW Bridge Design-Build Contract; Culvert Replacements
BRAC Ft. Belvoir Rte. 7100 Fairfax County Parkway at EPG Phase IV
Highway, Bridge, Culvert, and Trail construction and maintenance
ARRA- CIty of Chesapeake, Dismal Swamp Canal Trail
CHFS-DEPARTMENT FOR COMMUNITY BASED SERVICES
Improve the quality of day care providers and caretakers. Increase or maintain assistance to low income families through child care subsidies that enable families to work toward self-sufficiency.
Child Care Assistance to the needy and improved quality of providers
American Recovery and Reinvestment Act (ARRA) Supplemental Funding for the Child Care and Development Fund (CCDF)- The CCDF ARRA funds will be used to provide child care financial assistance to low-income working families, and fund activities t
Child Care and Development Fund, Recovery Act Funds
ARRA Supplemental Funding for the Child Care and Development Fund (CCDF): Provide child care financial assistance to low-income working families and fund activities to improve the quality of child care.
1.)  To assist those most impacted by the recession through the provision of funds to expand services to additional children and families facing difficult economic circumstances.  2.) To provide targeted funding for investments to improve the q
CONFEDERATED TRIBES OF WARM SPRINGS RESERVATION OF OREGON
This project is intended to improve the capabilities of the Alaska Earthquake Information Center (AEIC) and the Alaska Seismic Network (ASN) as part of the Advanced National Seismic System (ANSS). Upgrading outdated seismic station instrumentat
For the reduction of poverty, the revitation of low-income communities, and the empowerment of low-income families and individuals in rural and urban areas to become fully self-sufficient. This award will be used to assist tribal members and/or
Recipient will use ARRA funds to continue Community Access Program (CAP) activities in assisting low-income families and individuals who are in need of services for housing, clothing, food, and other necessities.
Provide Child Care financial assistance to low income working families and fun activities to improve the quality of child care
ARRA supplemental funding for the Child CAre Development Fund
Title: ARRA Supplemental Funding for the Child Care and Development Fund (CCDF);Description: Provide child care financial assistance to low-income working families and fund activities to improve the quality of child care.
ARRA Supplemental Funding for the Child Care and Development Fund (CCDF): Provide Child Care Assistance to low income working families and fund activities to improve the quality of Child Care.
GRANT# G-09PVAZCCD7 FOR THE AMOUNT OF $76,629.00  ARRA SUPPLEMENTAL (CFDA 93.713) DISCRETIONARY GRANT FUNDING FOR THE CHILD CARE AND DEVELOPMENT FUND (CCDF): PROVIDE CHILD CARE FINANCIAL ASSISTANCE TO LOW INCOME FAMILIES.
Deliverables: Service, electronic feedback installation and upgrade to existing Model G Gravity Meters (Quantity 2). Contract modified 14Dec2009 to include additional upgrade in order to retain analog output feature on both gravity meters. Cont
SUPPLY LIQUIDTIGHT FLEXIBLE NONMETALLIC CONDUIT AND FITTINGS IN SUPPORT OF THE HAWAIIAN VOLCANO OBSERVATORY
ARRA Supplemental funding for the Child Care and Development Fund (CCDF); Provide child care financial assistance to low-income working families and fund activities to improve the quality of child care.
The goals and objectives as well as the activities planned are geared directly towards job training and placement, with the added goal of creating jobs in targeted low income communities.  The major deliverables are: 1. To develop a radio press
Provide trained commercial truck drivers utilizing modern equipment to place in the workforce.
Training Commercial Truck Drivers Utilizing Modern Equipment
To purchase SimMan 3G Manikin and SimBaby Manikin to be used in training and providing qualified Practical Nursing and Medical Assisting personnel to the workforce.
Creating Energy Efficient and Green Communities)
HOUSING AUTHORITY OF THE CITY OF BUFORD GEORGIA
Water Line Replacement AND Miscelaneious Exterior Improvements
Conduct modernization activities at various Public Housing developments and demolition activities at a 100 unit Public Housing Development.  The modernization activities include renovation of bathrooms, installation of new energy efficient wind
continue modernization activities at GA 64-007 currently under phase 1 of comprehensive modernization. Contract will provide employments in all trades.
FFY2009 Capital fund Formula Grant to install HVAC systems in 30 dwelling units and to install water shutoff valves and replace sewer lines in 75 dwelling units.
HOUSING AUTHORITY OF THE CITY OF ELBERTON
HOUSING AUTHORITY OF THE CITY OF QUITMAN
ARRA capital fund grant for public housing program
Roofing replacement and security fencing at GA086000001P and GA086000002P
HOUSING AUTHORITY OF THE CITY OF NASHVILLE
Conduct modernization activities including installing security cameras, bullet proof glass, doors, architectural fees, replace water and sewer systems, site preparation, repair roads/parking, installing new security window screens, and replacin
Renovation of 4 public housing units to conform to Section 504 Handicap requirments.  The renovation included the installation of energy star refrigirators, water saver comodes and low flow showerheads.
Handicap Conversion of Public Housing Units
HOUSING AUTHORITY OF THE COUNTY OF HARRIS
Conduct modernization activities at 17 public housing units. The replacement of windows and exterior with energy efficient units.  Providing employment for carpenter trade, architect, and product manufactures in the US.
Window and Exterior door replacement in Swint and Blanchard Apartments.
ARRA -SBRP:  Environmental Exposure and Effect of Hazardous Chemicals(Administ Project 6 collaboration with Univ of Arizona - Casey Miller PI This project is a collaboration between Professors Gray and Miller at UNC and Professor Brusseau at th
ARRA -SBRP:  Environmental Exposure and Effect of Hazardous Chemicals(Administ
This supplemental funding will provide support for a collaboration between Boston University's Superfund Basic Research Program Research Translation Core and Brown University. The Boston University Superfund Research Program is an interdiscipli
Collaboration between Duke SBRC Project 6, Developmental Effects of Superfund Hydrocarbon Mixtures in Fundulus heteroclitus (Richard Di Giulio, PI) and University of North Carolina, Chapel Hill SBRC Project 1,  The Role of Oxidative Stress in T
Superfund chemical Impact on Development
This Superfund Basic Research and Training Program-Reuse in RI: A State-Based Approach to Complex Exposures-tackles through research and outreach three inter-related thematic challenges: 1) land reuse, 2) a state-based approach, and 3) complex
REUSE IN RI: A STATE-BASED APPROACH TO COMPLEX EXPOSURES
The overall goal of the Alzheimer&apos;s Disease Research Center (ADRC) at Johns Hopkins University (JHU) is to facilitate research in Alzheimer&apos;s disease (AD) and related disorders throughout the research community at JHU and associated i
.  The first provides salary support for personnel and animal/supply support to conduct experiments on a new therapeutic agent for protection or regeneration of articular cartilage in osteoarthritis, using mouse models.  The second provides tec
TRANSLATING MOLECULAR SIGNAL PATHWAYS TO ORTHOPAEDIC TRAUMA CARE
Glioblastoma Multiforme (GBM) is the most aggressive form of glial neoplasia and accounts for approximately 60% of all malignant primary brain tumors. Although current standard therapy targeting GBM incorporates surgery, radiation, and chemothe
The central focus of the parent grant is to address the health concerns of women and their developing offspring affected by drug abuse by providing the optimal environment to encourage and facilitate clinical and translational research. The app
SEX AND GENDER INFLUENCES ON ADOLESCENT DRUG INVOLVEMENT
to introduce systems biology research to advanced undergraduate and beginning graduate level students and offer a 10 week internship in the laboratory of one of the participating co-investigators.
GENOMIC APPROACHES TO COMMON CHRONIC DISEASE
The purpose of the administrative supplement is to accelerate the tempo and amount of data acquisition, coding, and analysis for three of the five center projects.  This will be accomplished by hiring additional staff, enabling increased hours
PREDICTING AND PREVENTING THE DEVELOPMENT OF LEARNING D
Through the hiring of two new research associates, the requested support will enable us to  enhance research goals and capacities through infrastructure support for mulitple investigators by increasing the number of human brains available for s
Inhibition, Oscillations and Information Processing in Schizophrenia
The goal of Project I is to examine candidate genes based on the convergence of evidence as a PD risk factor from different studies (association, linkage and expression), and to enhance these efforts by including analysis of complex genetic and
The goal of this ARRA application is to accelerate the pace of the current scope of the PENN Udall Center while adding retaining jobs. Briefly, the goals of this Udall Center are to elucidate mechanisms of brain degeneration in patients with Pa
This NCRR ARRA supplemental application for the Tulane National Primate Research Center (TNPRC) provides two years of funding to support and accelerate translational research efforts at the TNPRC by enhancing information and communication netwo
This Administrative Supplement to the New England Primate Research Center (NEPRC) Base Grant (P51 RR000168-48) is to support the development of a new translational laboratory animal model directed at understanding the relationship between commo
This proposal seeks the continuation of the University of Chicago Diabetes Research and Training Center (DRTC). The Center is an interdepartmental and interinstitutional cooperative endeavor involving investigators from the University of Chicag
The primary aim of the parent grant is to identify and characterize bladder cancer stem cells (CSCs),  In this administrative supplement, we propose the procurement of a cutting edge technology (the Fluidigm System) that was developed in Stanfo
Identification and characterization of bladder cancer stem cells - Equipment Supplement
The purpose of the award is to purchase a gas chromatograph (GC) to replace an aging model which is beyond warranty and for which we can no longer get parts or a service contract from the manufacturer.
Immunization to Block the Effects of Nicotine
Recent pilot studies have suggested that plasminogen activator inhibitor-1 (PAI-1) plays a key role hepatic regeneration. This surprising finding is contrary to the dogma that PAI-1 plays an antiproliferative role in hepatic regeneration by inh
The aim of this administrative supplement is to enhance our ability to address the original aims of this grant. We found that a brief exposure to 10-50 mM ethanol prior to cardiac ischemia reduces infarct size by -70% in a process that is depen
Mechanisms of Ethanol-Induced Cardiac Protection
of alcohol dependence, and to aid in the development of new therapeutic approaches.
Alcohol, Estrogen Replacement Therapy (ERT) and Cognition in Menopaysal Women
It is well-established that responses to some drugs differ among ethnic groups due to variations in genetic background. Alcohol is one of these agents, with rates of alcoholism being more prominent in certain races than in others. Among the mor
Alcohol Pharmacogenetics in Mexican Americans
Excellent longitudinal data are available on the development of alcohol use and abuse across the college years but little is known about the behavioral risks (e.g. risky sex, aggression, academic failure) that have been associated with collegia
ALCOHOL AND BEHAVIORAL RISKS THROUGHOUT COLLEGE
(ARND). Some of the hallmarks of observed cases of ARND bear a striking similarity to those seen in individuals with mutations in the cell adhesion molecule (CAM) L1.The overall goals of this grant are to determine the nature and mechanism of
Exposure of a fetus to ethanol can lead to the development of fetal alcohol syndrome, which is characterized by various morphological and behavioral deficits in fetal alcohol-exposed (FAE) offspring. These offspring often show clinical sleep-wa
Fetal Alcohol Effects on Ciradian Clocks and POMC
Adolescents suffer many acute adverse consequences from alcohol use. Recent epidemiological findings have linked adolescence to the development of alcohol abuse and dependence. This co-occurrence suggests that the processes of adolescent develo
ALCOHOL EXPECTANCIES: MEDIATORS OF BIOPSYCHOSOCIAL RISK IN EARLY ADOLESCENCE
In this proposed competitive revision, we are adding a longitudinal component for people in early abstinence to our funded R01 studying clinical issues and CNS disinhibition in short- and long-term abstinent alcoholics compared to non-alcoholic
LONG-TERM ABSTINENCE CLINICAL ISSUES AND CNS DISINHIBITION
According to the U.S. Center for Disease Control, young people under the age of 25 are the segment of the population in the U.S. at the highest risk for HIV and other STDs. Of those under 25, individuals involved in the juvenile justice system
HIV prevention with adolescents: Neurocognitive deficits and treatment response
The purpose of this administrative supplement is to accelerate progress of the parent R01 by defining the secretory phenotype of senescent preadipocytes using expression profiling approaches. This is based on new data since the parent grant was
Effect of Aging on Preadipocyte Differentiation
state. The specific aims will be to: 1) Measure the response of human articular chondrocytes, isolated from donors of different ages, to IGF-I when the cellular redox status has been modulated; 2) Determine the redox sensitive cell signaling m
Our long term goal is to determine the molecular mechanisms underlying the diminished skeletal muscle performance with age. We hypothesize that age-dependent damage of specific amino acid residues in key skeletal muscle proteins impacts skeleta
Structural and Calcium Regulatory Proteins in Sarcopenia
Project Title: Interaction of caloric restriction with longevity genes Calorie restriction (CR) and longevity genes related to growth hormone signaling prevent age-related disease, extend healthspan and increase life expectancy.  Studies of mic
Interaction of Caloric Restriction with Longevity Genes
Cerebral deposition of ?-amyloid peptides (A?) is one of the pathological hallmarks of Alzheimer’s disease. A? is generated by sequential proteolysis of amyloid precursor protein (APP) by BACE1 and ?-secretase. ?-secretase is a multimeric pro
CELL BIOLOGY OF PRESENILIN 1 AND ASSOCIATED PROTEINS
Manual dexterity is fundamental for maintaining independence in many basic and instrumental activities of daily living. Two important components of skill learning are the learning process itself (motor acquisition), and the ability to transfer
Human skin, like all other organs, undergoes alterations as a consequence of the passage of time. In aged human skin, the dermal connective tissue architecture undergoes progressive degradation, which impairs skin function and causes skin to be
COLLAGENASE DEGRADATION IN EXTRACELLULAR MATRIX IN AGING
To accelerate research described in Specific Aim 2 of the parent grant, I am requesting an administrative supplement to hire and support a new Postdoctoral Fellow (Ryan Ragland, Ph.D.) for two years. Our unexpected finding that p53 absence does
The role of ATR in preventing age-related diseases
Aging is not a uniform process among individuals. There are persons who rapidly develop age-related kidney disease, cardiovascular disease, frailty and anemia. The underlying cause(s) of age-related kidney disease are not clear, but glomerulosc
TNF-ALPHA UNDERLIES GLOMERULAR AGING IN B6 FEMALES
Stem cells provide for the maintenance and regeneration of organs and tissues throughout life, and loss of the regenerative capacity of tissues such as blood and muscle has been attributed to decreased stem cell activity. The ability of stem ce
Characterization of age-related changes in stem cell behavior
Dietary restriction (DR) increases lifespan and delays the onset of age-dependent diseases. The overarching goal of this proposal is to identify the molecular mechanisms underlying the benefits of DR on longevity. The energy-sensing AMP-activat
Molecular mechanisms underlying lifespan extension by dietary restriction
Inclusion body myopathies (IBM) are disabling skeletal muscle disorders and considered a prototypical age related muscle disease. There is no effective treatment. IBM muscle has characteristic 'rimmed vacuoles' and eosinophilic inclusions. Thes
Aging of the cardiovascular system is characterized by a reduction in cardiac function, and cardiovascular disease frequently strikes in the latter half of life. Many experimental findings suggest that adult mammalian myocardium has a populatio
Aging and Myocardial Progenitor Recruitment (Administrative Supplement - Equipment Only)
. This COBRE has a proud record in mentoring and networking, as well as superb Core Facilities. Thus, the outstanding young investigator to be covered by this supplement will benefit from interactions with this COBRE and be groomed for eventual
This proposal describes the research and training opportunities for two undergraduate students working for 12 weeks in the summers of 2009 and 2010 on RNA editing in African trypanosomes. The parent grant AI021401-24 addresses the mechanism and
Function of mRNA Editing in Trypanosomes
HIV-1 reverse transcriptase (RT) is a central target for antiviral treatment of AIDS and detailed knowledge of its structure and function has important clinical and biological consequences. Both nucleoside and non-nucleoside RT inhibitors are u
HIV-1 Reverse Transcriptase Structure: Function, Inhibition and Resistance
Funding is for a supplement to a grant entitled, “Determinants of Borrelia burgdorferi Hematogenous Dissemination”; the long-term objective of the project was elucidation of genes/proteins that mediate B. burgdorferi virulence. Lyme disease
Enhancing immune effector mechanisms and dampening immune regulation may be controlled by a new cellular circuitry involving Treg and mast cells. The funded grant, 5R01AI048667-07, 'Effector Mechanisms in Graft Tolerance', demonstrated that mas
Tuberculosis has been declared a global emergency by the WHO and a priority for vaccine development by the NIH. The currently used BCG vaccine offers variable protection against children but not adults. Various sub unit and DNA vaccines and att
CHRACTERISTICS OF AN M. TUBERCULOSIS DERIVED VACCINE
Mast cells (MCs) are important in allergic diseases, tissue injury, and protection from infections. MC numbers and their effector functions are dynamically regulated by constituents of the tissue microenvironment. This application for continued
CysLT and P2Y Receptors in Lung Inflammation
This project will determine the HIV-l envelope changes necessary for the virus to use different cell surface molecules for entry. Recent progress has shown HIV-l subtype-specific preference for alternative coreceptors, and suggests different ta
This is an administrative supplment grant request to the NIH to purchase a new ultracentrifuge and rotor.  The equipment is to replaced an old instrument that can no longer be serviced.  The equipment will be used for purification of proteins,
The past several years have seen major progress in the delivery of treatment and care to HIV-infected people in the developing world. However, substantial uncertainty persists regarding optimal treatment strategies, the cost of second- and thir
Optimizing HIV Care in Less Developed Countries
Human cytomegalovirus (HCMV) is a beta-herpes virus that can establish persistence and latent infections. HCMV can cause morbidity and mortality in immuno-compromised individuals such as transplant-recipients and HIV-infected persons. In fact,
DOWN-REGULATION OF MHC CLASS L MOLECULES BY HCMV US2
Three undergraduates have all started working on sub-projects relating to a parent R01 award 'APOBEC3 proteins and uracil in retrovirus restriction'.
APOBEC Proteins and uracil in retrovirus restriction
Viruses are potent cancer-inducing agents. While the clinical effects of cancer are obvious, its cellular and molecular causes are not fully understood. Here we propose to study the cellular entry mechanisms of polyomavirus (Py), a non-envelope
TRANSPORT OF POLYOMAVIRUS ACROSS THE ER MEMBRANE
Project Summary: The immunological synapse (IS) is the dynamic interface between an immune cell and the cell that it is recognizing. A major function of the IS is directed secretion, which allows specific targeting of immune effector function.
DIRECTING FUNCTION AT THE NATURAL KILLER CELL SECRETORY IMMUNOLOGICAL SYNAPSE
We request funds to purchase a BD Biosciences FACSAria II high-speed cell sorter. The instrument will be used by investigators studying immune response to viral infection in animal models. Viral pathogens include highly pathogenic influenza inc
ARRA Pandemic Potential of H5N1Influenza Viruses
The research project is on the development a vaccine against schistosome infection which affects over 200 million people with an additional 790 million at risk in 74 countries. Two High School Biology teachers from Lubbock High School worked as
Experimental Molecular Vaccines for Schistosomiasis
Human granulocytic anaplasmosis (HGA; formerly human granulocytic ehrlichiosis) is an emerging and potentially fatal disease and the second most common tick-borne infection in the United States. The etiologic agent is Anaplasma phagocytophilum,
Characterization of Anaplasma phagocytophilium adhesins
Asthma affects millions of people worldwide and has been gaining prevalence in the US. Symptoms of allergic asthma include airway inflammation, increased numbers of eosinophils in BAL and sputum, and airways hyperresponsiveness. While the role
EOSINOPHILS AND ALLERGIC AIRWAY RESPONSES
This administrative supplement to R01 AI074074 was for acquisition of an item of equipment, a Li-COR Odyssey infrared imaging system. This allows accurate protein quantification of western immunoblots, and 'in-cell' or 'on-cell' westerns. This
SOLUBLE T CELL RECEPTOR STUDIES ON MHC RESTRICTION
This is a proposal for a supplement to fund three undergraduate students to work in the lab during the summers of 2009 and 2010.  These students will accelerate the tempo of the science while learning valuable laboratory procedures.  Hopefully,
Ultrapotent Inhibitors of Wild-type and Multi-drug Resistant HIV
We request administrative supplement to hire new personnel and to purchase instrumentation that will accelerate the pace of the parent funded project (1R01-AI076119-01) and enhance the efficiency of the proposed research. The project focuses on
Ultrapotent Inhibitors of Wild-type and Multi-drug Resistant HIV -Admin Supplement
Funds were provided to hire and pay summer undergraduate researchers $8/hour for 40 hours/week to work in a research laboratory studying the pathogenesis of Giardia - a common waterborn parasite.
Subproject for Institution # 08-002587: Molecular Architecture, Function, and Biogenesis of the Ventral Disc in Giardia intestinalis
231 Briggs Hall / Department of Microbiology
During its replication cycle in red blood cells, the human malaria parasite Plasmodium falciparum ingests and catabolizes up to 75% of the host cell's hemoglobin in an acidic degradative organelle called the food vacuole. Hemoglobin catabolism
Roles of two aminopeptidases in peptide catabolism in the malaria parasite
Inhaled corticosteroids (ICS) are considered first-line therapy for the management and control of patients with persistent asthma. Use of inhaled steroids has been associated with reduced airway responsiveness, improved lung function, diminishe
Pharmacogenomics of Inhaled Corticosteroid Responsiveness in Patients with Asthma
Henry Ford Health System - Ctr Health Services Research
The thymus is the primary lymphoid organ responsible for the production of T cells, and its function is required for the generation of cellular immunity in vertebrates. The stromal cell types in the thymus form a complex meshwork of microenviro
FoxN1 and Molecular Mechanism of Thymic Involution
This Supplement will provide summer research opportunities for four high school (HS) students and four undergraduate students over two summers. Consistent with ARRA, students will gain experience that can launch careers into biomedical research
Validation and Development of Trypanosomal Phosphodiesterase Inhibitors for Treatment of Sleeping Sickness
Upon contact with bone, matrix-derived signals in the RANKL-induced osteoclast (OC) prompt the cell to polarize its cytoskeleton, eventuating in formation of an isolated microenvironment between the polykaryon and skeletal surface. Ultimate deg
MECHANISMS OF RANKL MEDIATED OSTEOCLAST ACTIVATION
Systemic sclerosis (SSc) is a devastating condition with no disease-modifying treatment. Fibrosis, the hallmark of SSc, is caused by fibroblast activation with collagen overproduction and myofibroblast differentiation. Transforming growth facto
Fibroblast TGF-beta/Signaling in Scleroderma: Modulation by PPAR-Gamma
This proposal is aimed to achieve 3 broad objectives a) to enhance the tempo of research proposed in the parent grant using enhanced breeding strategies as well as  pursuing complementary approaches to the remaining aims of the parent proposal,
Pathogenesis of autoimmune myositis:Role of MHC Class 1
Intervertebral total disc replacement (TDR) implants potentially herald a paradigm shift in the management of degenerative disc disease. Preservation of motion may avoid adjacent-segment degeneration, a well- recognized complication of fusion.
Wear Analysis of Intervertebral Total Disc Replacements
This proposal seeks to determine the feasibility of targeted therapy against the autoantibodies that cause the blistering in this disease. We will screen pharmacological compounds and other small molecules, that could potentially be developed i
Cloning and genetics of human pemphigus autoantibodies
This award is an administrative supplement for AR053353, “Inducing Skeletal Repair Using Mechanical Stimulation”.  The overall hypothesis of the parent grant is that functional, hyaline-like cartilage can be formed postnatally via mechano-r
Inducing Skeletal Repair by Mechanical Stimulation
This is a Public Housing Capital Fund Stimulus Formula Grant. It is for the installation of a security camera; stoves, refrigerators, water heaters in thirty-five (35) units; and the roof replacement on thirteen (13) units.
HOUSING AUTHORITY OF THE CITY OF OCILLA GEORGIA
ARRA FUNDING PAYS FOR 1 FULL TIME ARCHITECT,  2 FULLTIME PROJECT COORDINATORS,  2 FULL TIME ADMINSTRATIVE PERSONELL,1 FULL TIME BOOKKEEPER
Replace obsolete windows with energy efficient windows. Replace obsolete HVAC, PHA Wide.
Architecture & engineering services and installation of new heat and air.
Modernization activity replacing stoves and refrigerators, HVAC units, tile, replacing cabinets, hot water heaters and painting
Capitol Fund Program grant for modernization of Public Housing.
Tennile Homes Circa 1960. Complete Renovation of Bathrooms 35 units, Ga195-001
Public Housing Capital Fund Stimulus Grant
work has already been completed and reported
This is a Public Housing Capital Fund Stimulus Formula grant.  It is for the installation of energy efficient water heaters, stoves, refrigerators in twenty (20) units and the replacement of roofs on three (3) units.
Invest in public transportation in rural areas of Georgia by purchasing new vehicles, upgrading rural bus facilities, procuring scheduling software and installing intelligent transportations systems technology on vehicles.
Georgia Statewide Rural Transit Grant: 182 vehicles, ITS, facilities, software
Invest in publc transportation by purchasing new 35 Ft Low Floor Clean diesel transit buses, 30 Ft Low Floor Trolley buses, install bus security cameras and annunciation systems on buses and replacing worn out transit enhancements to include bu
Purchase of four (4) replacement buses, three (3) replacement Trolleys, Enhancement replacement and security equipment installation.
This grant is for FY 2009 ARRA Economic Stimulus Funds. The funds will be used to purchase seven(7) 30-foot replacement vehicles. The buses will be hybrid electric/diesel buses. These vehicles have a useful life of seven(7) years/350,000 miles.
CAT ARRA 7 replace bus/Trans Enhancement
HOUSING AUTHORITY OF THE CITY OF PERRY, THE
American Recovery ReinvestmentActCapital Fund Formula Grant
Goodyear - Various Locations Citywide - Functionally Classified Roadways
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).   AfricaArray will create a preeminent and sustainable pipeline program for increasing the representation of African-American and Hispanic student
Collaborative Research: Track 2: Enhancing Diversity in the Geosciences through the AfricaArray Educational Alliance
, Yale geoscience faculty, and the LSAMP program at the University of Connecticut. The aim of the GeoCORPS program is to provide a diverse group of Grades 9 - 12 students with a comprehensive pipeline that comprises multiple opportunities to ex
Track 1 Geo. CORPS:Pipeline for Success in the Geosciences
SURRGE is a three-year collaborative project at Southern Illinois University Carbondale (SIUC) that investigates how student interest in the geosciences is affected by 1) a reader that presents culturally relevant geoscience topics with the ins
Track I: Southern Illinois Undergraduate Recruitment and Retention in Geoscience Education (SURRGE)
Southern Illinois University at Carbondale
Heritage District Downtown Pedestrian Project - Gilbert
Reliable and efficient energy scoring functions are highly needed and vitally important for accurate protein structure prediction, protein and rational therapeutic design. Unfortunately such energy scoring functions still remain at large. In th
A new scoring framework for selecting structural models
Building Information Model support and mechanical and electrical rennovations to an existing federal office building in Jackson MS
Provide engineering services for the retro-commisiioning of building systems at McMaddon Couthouse Building in Bridgport CT, Giamo Fedeal Building in New Haven, the Federal Courthouse and Pastpre Federal Building in Providence. The intent of th
GRUZEN SAMTON ARCHITECTS PLANNERS & INTERIOR DESIGNERS LLP
Continuing construction administration services for the renovation of Emanuel Celler Courthouse.  **Although the stimulus money received did not provide full time employment for the job descriptions listed under Description of Jobs Created, it
Building renovation of half of the building at the Emanuel Celler US Courthouse.
Provide on site technical support, contract administration and project management services on minor and major recovery funded projects to the General Services Administration (GSA) Regional Office  in Philadelphia, PA through all project phases,
ALPHA CONSTRUCTION AND ENGINEERING CORPORATION
The objective of this project is to install a large Photo Voltaic Panel array on the roof of the Spotsylvania W. Robinson III and Robert R. Merhige, Jr.. United States Courthouse in Richmond, Virginia.  The project will supplement the electrica
BOYNTON, ROTHSCHILD, ROWLAND ARCHITECTS, PC
Bidding and Construction phase Architectural services for reroofing of the Abingdon, VA courthouse; including 2 site visits, review of Contractor's submittals, response to Contractor questions, and response to questions from the Owner's Represe
Renovation of the 1st and 2nd Floor Restrooms in the Elizabeth Kee Federal Building, Bluefield, WV
Heery International is providing Construction Manager as Agent (CMa) services for the renovation of the George C. Young Federal Building and Courthouse located in Orlando, FL.  The services include; attending design meetings and preparing agend
The project consist of the renovation / modernization of the Dr. A.H. McCoy Federal Building located in Jackson, MS.  The scope of work includes a complete renovation of the building's 15 floors.  The project also consist of replacing all major
The award of Construction Manager as Constructor includes providing all professional, technical, administrative and clerical personnel as needed to perform Design Phase Services and Construction Phase Work for the full modernization of the Robe
The Project is the restoration of the Chicago Federal Center (CFC) Plaza. The plaza is surrounded by the Dirksen Federal Courthouse, Kluczynski Federal Building and the United States Postal Service Loop Station. The three buildings and plaza we
Planning and designing for the recommissioning and retro-commissioning of the existing US Courthouse Building in order to improve the energy efficiency and minimize the environmental impact of the existing building.  This work includes a pre-de
Study to investigate three existing 300 ton chillers with one that will be more fuel efficient.
Replace curtain wall windows, Federal Building, Mt. Vernon, IL
A/E Services under ARRA funding include:  new advance metering, total building re-commissioning/retro-commissioning assistance, window replacement, façade repair and restoration, cafeteria remodeling with EnergyStar equipment upgrades, HVAC im
SUPPLY AND DELIVERY OF FLOATING LOG AND DEBRIS AND DAM SAFETY BARRIERS.
Unlaminated Plastics Profile Shape Manufacturing
Recovery lghting replacement at The Ronald Dellums Federal Building, 1301 Clay Street, Oakland, CA.   Furnish and install lighting fixtures.
Project is to remove and replace approximately 48,000 Square Feet of deteroriated roof system and install new cool roof system meeting Energy Star requirements.
Asphalt Shingle and Coating Materials Manufacturing
ELECTRICAL PANELBOARDS FOR TEMPORARY SERVICE
Switchgear and Switchboard Apparatus Manufacturing
SQUARE D CLASS 7320 PADMOUNT TRANSFORMER
Architectural/Engineering Design Services for Land Port of Entry at Columbus, New Mexico.  The goal of the project is to design a Net Zero Energy Facility.
Other Architects & Engin Gen-Document the hisstorical significance of the Montana Dakota Utility Building in accordance with Montana State Historic Preservation office guidelines and regulations.
Coordinated effort between structural roof studies and electrical study to generate drawings for the design/build project to install new solar panels on a series of buildings at the DFC
The David Skaggs Research Center is located at 325 Broadway in Boulder, Colorado.  It is 415,000 sf. And completed in 1999.  The building's exterior construction has a concrete superstructure, applied precast concrete and native sandstone with
Retro-Commissioning Services at the Fort Collins Federal Building.
Environmental studies for proposed lease site in Billings MT.
Office of the Federal Acquisition Service
Award executed to allow for accelerated deployment of the HIS Electrnic Dental Records System. Acceleration of the schedule will allow program to maintain more active teams in the field at the present time vice maintaining a much smaller comple
Approximately 50-70% of patients with chronic pain, particularly fibromyalgia sufferers, report sleep difficulties. Because it is not possible to randomly induce chronic pain or chronic insomnia in otherwise healthy participants, the exact natu
SLEEP AND PAIN INTERVENTIONS IN FIBROMYALGIA: HYPERALGESIA AND CENTRAL SENSITIZAT
Osteoarthritis (OA) affects 27 million Americans, many of whom have concomitant symptomatic meniscal tear. Arthroscopic partial meniscectomy (APM) is the surgical procedure used to treat these patients when conservative measures are not success
Partial meniscectomy vs. nonoperative mgmt. in meniscal tear with OA: an RCT
The innate immune system comprises several classes of pattern recognition receptors, including Toll- like receptors (TLRs), NOD-like receptors (NLRs), and RIG-1-like receptors (RLRs). TLRs recognize microbes on the cell surface and in endosomes
ROLE OF CRYOPYRIN INFLAMMASOME IN AUTOINFLAMMATORY DISEASES AND HOST DEFENSE
Merlin is the product of the neurofibromatosis type 2 (NF2) gene. In humans, loss of merlin is associated with the development of a variety of tumors including schwannomas, meningiomas, ependymomas and mesotheliomas. That both NF2 alleles must
Structure, Function and Regulation of Merlin
It is widely accepted that the p53 tumor suppressor restricts abnormal or DNA damage-exposed cells before damage to DNA is converted to inherited mutation by induction of growth arrest or by triggering apoptosis. This process depends mainly on
Cell fate decision in response to p53-dependent DNA damage/genotoxic stress
Human cytomegalovirus (HCMV) is the prototypical member of the beta-herpesvirus family. Epidemiological studies have shown that HCMV infection is widespread. In healthy individuals infection is generally asymptomatic, but the virus can cause se
CYTOMEGALOVIRUS IMMEDIATE EARLY PROTEINS AND VIRION RNAS
The overall goal of this investigation is to determine the molecular distinctions between estrogen agonism and antagonism in hormone dependent tissues and cancers and to use this information to develop and characterize novel compounds that can
DEVELOPMENT AND CHARACTERIZATION OF NOVEL SERMS
Chromosomal translocations are highly associated with cancer development. Both Nbs1 (Nijmegen breakage syndrome) and Mrell (ataxia-telangiectasia-like disorder) deficient patients exhibit increased levels of chromosomal translocations and highe
Role of The Mre11/Rad50/Nbs 1 Complex in DNA Damage Response Pathways
In this supplement, we will test the predictive role of two amplification events and gene fusion status in alveolar rhabdomyosarcoma by testing samples from a single clinical trial. This study will involve applying our assays for amplification
COG Studies of Gene Amplification in Rhabdomyosarcoma
Cancer predisposition syndromes are autosomal dominantly inherited conditions in which the affected individuals have a high relative risk for developing cancer. PTEN and neurofibromatosis-2 (NF2) are tumor suppressors that are inactivated in bo
CONNECTING PTEN AND NF2 CANCER PREDISPOSITION SYNDROMES
We recently described a novel protein, Growth Inhibition and Death E3 Ligase (GIDE), a mitochondrially located E3 ubiquitin ligase.  GIDE contains a C-terminal RING finger domain, which is similar in sequence to that of Inhibitor of Apoptosis P
AMID in Apopotosis and p53 Mediated Downstream Effects
, we have identified and validated a 4-biomarker panel that recognizes early stages (I-IIB) ovarian cancer with high sensitivity of 86% at 98% specificity. Recently published data indicated that performance biomarker combinations with added cla
Multianalyte Assay for Early Diagnosis of Ovarian Cancer
The ultimate goal of this proposal is to identify biomarkers that can determine which patients presenting with non-small cell lung cancer (NSCLC) have metastasis. While some patients present with overt metastatic disease, others may have more s
Discovery of Biomakers for Lung Cancer Metastasis
The purpose of this award is to create new job and accelerate our research on SRC-1 and breast cancer. Our first task is to use the budget to hire a cancer research scientist with a citizenship of United States who will lose his job in August o
'We aim to utilize expression microarrays to define gene expression profiles in a large cohort of FLT3/ITD AML patients who relapsed and contrast them to the expression signature in patients in long term remission.  Funds from this administrati
Biology and Prognostic implications of Flt3 mutations in AML
Cancer is one of the leading health disorders that can lead to impaired functioning and mortality in the elderly. During the cancer survivorship period, a patients' symptoms may go unrecognized or be poorly managed. Family involvement in care p
Caregivers' Strengths and Skills in Managing Older Cancer Patients' Symptoms
This award, issued under the American Recovery and Reinvestment Act of 2009, is a supplement to my NCI supported grant entitled “ Mechanistic Analysis of Papillomavirus E2 Functions”. The human papillomaviruses are associated with a number
Mechanistic Analysis of Papillimavirus E2 Functions
The HPLC system requested is to measure the fate of chemopreventive agents delivered via dietary route or systemic route by measuring the plasma or tissue levels of the compounds to understand the mechanism and allow identification of their met
We have employed two post-doctoral fellows, one with a background in physics and one with a background in mechanical engineering to accelerate the realization of the dual-panel breast-dedicated PET system proposed by the parent project.  Since
Advanced PET System Dedicated to Breast Cancer Imaging
is being used to purchase a Nikon Ti-E Inverted Microscope with Epi-Fluorescence and Phase Contrast.
Mechanisms of Cell Death after Photodynamic Therapy
Melanoma, the most rapidly increasing malignancy in the United States, accounts for only 4% of all skin cancers but is responsible for nearly 80% of skin cancer deaths. If detected early, the disease is easily treated, however, once the disease
This supplemental request complements the parent grant in that the supplement proposes to create a CRAd that has greater oncolytic potency than the CRAd that was previously considered for imaging modification in the parent grant. The oncolytic
MONITORING OF ADVANCED VIROTHERAPY FOR OVARIAN CANCER
Human papillomavirus (HPV) infection of anogenital tissues has been implicated as a requisite step in the progression to neoplastic transformation. The role of HPV in cervical cancer has been well elucidated; however, most infections with HPV d
INTERACTION OF EBV AND HPV IN THE DEVELOPMENT
We are exploring a set of questions within the scope of the parent grant. The first concerns single women insured through their own employer - women who do not have the option of relying on a spouse as an alternative source of health insurance.
Health Insurance, Labor Supply, and Health
By some estimates, 50% of the 56,000 US colo-rectal cancer (CRC) deaths per year in the US could be prevented by appropriate, risk-based CRC testing.  Hispanics have lower incidence and mortality from CRC, but are typically diagnosed at later s
Facilitating Risk-Appropriate Colorectal Cancer Testing - ARRA Stimulus Admin Suppl
In the present proposal, our preliminary data demonstrates that beta1 integrin inhibition enhances the therapeutic efficacy of IR in vivo; these promising findings have the potential to impact clinical RT for patients. We hypothesize that beta1
Manipulating b1 integrin to enhance radiation therapy for breast cancer
Re-activation of maspin tumor suppressor gene by designed transcription factors The overall purpose of this project is to develop novel delivery systems to introduce an Artificial Transcription Factor with anti-metastatic activity into primary
Re-activation of maspin tumor suppressor gene by designed transcription factors
The immediate goal of this three month project is to purify a fragment (60kDa) of the EGF receptor that is generated when cells are treated with EGF. The fragment is generated by rhomboid proteases, which cleave transmembrane proteins within th
Role of the SEC61 Translocon in EGF Receptor Trafficking and Signaling
We propose to accelerate the application and validation of the PEPPeR platform to biomarker discovery using lung tissue interstitial fluid (TIF) for discovering biomarkers in lung adenocarcinoma. A relatively large set of 20 TIF samples (10 con
A PLATFORM FOR PATTERN-BASED PROTEOMIC BIOMARKER DISCOVERY-R01
The broad objectives of this research project are to develop effective intervention methods for long-term maintenance of healthy lifestyle behaviors (exercise and diet) in older adults to improve their health status and quality of life. The spe
The supplemental funding will be used to accelerate development of a dedicated dissemination Web site to provide the health research community with easy access to a variety of geospatial databases being developed under the parent NIH-funded res
Geospatial Factors and Impacts: Measurement and Use
Breast cancer is a disease for which personalized risk prediction could vastly improve care.  Our currently funded R01 has enabled us to develop an algorithm called view learning that integrates predictive data from a complex multi-relational m
ARRA Machine Learning for Improved Mammography Screening
We have completed analysis of over 250 lung cancer samples by a high- resolution genome profiling method developed here at Cold Spring Harbor Laboratory (CSHL). We found twelve major recurrent amplicons, most of which contain known driver genes
IDENTIFICATION & CHARACTERIZATION OF DRIVER GENE(S) INRECURRENT LUNG CANCER AM
Vitamin D, as measured by serum 25(OH)D, is prevalently low in older people, and more than 60% of North American female populations are below the optimal level. Low vitamin D is a serious problem since optimal serum 25(OH)D concentration is ess
Clinical Trial of Vitamin D3 to Reduce Cancer Risk in Postmenopausal Women
The success of molecularly targeted cancer therapy using tyrosine kinase inhibitors (TKIs) faces a number of difficult challenges. Foremost among these is the ability to identify subsets of different cancers that are uniquely sensitive to targe
Circumventing Acquired Resistance to Growth Factor Receptor Kinase Inhibitors
Progression and metastasis of solid tumors is a principal cause of death for cancer patients. The childhood muscle cancer alveolar rhabdomyosarcoma is a classic example. A gap in understanding the disease-specific mechanisms of progression unde
THERAPEUTIC TARGETS IN ALVEOLAR RHABDOMYOSARCOMA
NOT-OD-09-058: NIH Announces the Availability of Recovery Act Funds for Administrative Supplements This Administrative Supplement proposes feasible aims that will enhance all of our funded NIH grants but especially the highly significant parent
RNA-BASED IMMUNOTHERAPY TARGETING ANTIGENS UNIQUE TO BRAIN TUMOR STEM CELLS
There is a very large unmet therapeutic need to treat humans that abuse illegal drugs, especially cocaine. To address this unmet need, this application is focused on the design, synthesis and pharmacological characterization of potential anti-c
Aminobenzomorphan:  Potential Cocaine Abuse Medications
This grant provided a summer research experience for 19 science teachers in health-related scientific research.
Intron-based Mutagenic Transposons for Zebrafish
In the parent project to this competitive revision application, we are currently evaluating the comparative effectiveness and cost-effectiveness of a web-based psychosocial treatment intervention with individuals in methadone maintenance treatm
Computer-Delivery of Effective, Psychosocial Interventions in Methadone Treatment
It has recently been discovered that glia become progressively more activated upon repeated exposure to morphine, & that this glial activation, in turn, modulates morphine's effects. This discovery was originally made in the context of studying
Exploring the Potential of Glia for Regulating Clinically Relevant Opiod Actions
This Competitive Revision enhances medication development for treatment of cocaine dependence by expanding the scope of a study evaluating the efficacy of a pharmacotherapy (D-cycloserine) in facilitating extinction to cocaine-related cue react
D-Cycloserine Facilitation of Cocaine-Cue Extinction
The focus of this research is cochlear hearing loss and its effects on the perception of simple and complex sounds and the ability to understand speech.  Hearing loss is one of the most common chronic conditions of aging and contributes to poor
Auditory Analysis and Speech Recognition
In this supplement application, we propose two studies that expand  two specific aims in the parent grant in directions that will form a foundation  for a new R01 grant focusing on learning and treatment processes in aphasia. In each study, we
Lexical retrieval verbal short term memory and learning
Disruption of vestibular signals from one labyrinth results in asymmetries in the angular vestibuloocular reflex (VOR) evoked by high-frequency, high-acceleration head movements. Studies during the previous funding period have elucidated linear
The mammalian olfactory epithelium does two remarkable things with its olfactory sensory neurons. These neurons detect odorants, translating the structure of volatile chemicals into a neural information code, and the epithelium can replace thes
Functional Domains and Expression of Olfactory Receptors
During the past few years my laboratory has explored the involvement of taste signaling elements in gastrointestinal (GI) chemosensation. In particular, how macronutrients in the gut lumen are sensed and in turn regulate hormone release from sp
FUNCTIONAL CHARACTERIZATION OF ENDOCRINE TASTE CELLS
The goals of this study are to demonstrate and confirm the role of genetic factors in the development of chronic otitis media with effusion and recurrent otitis media (COME/ROM) to improve understanding of its underlying biological and patholog
Genetic Epidemiology of Chronic/Recurrent Otitis Media
DESCRIPTION (provided by applicant): Normal vocal fold vibration is crucially dependent upon tissue composition and viscoelasticity. When composition of the extracellular matrix (ECM) of the vocal fold cover (i.e., lamina propria) is altered, v
ARRA Engineering the Vocal Fold Extracellular Matrix SUPPLEMENT
: This project is being supported with funds from the American Recovery and Reinvestment Act, which may involve a reduction in the research aims and scope. If necessary, a revised abstract will be posted soon and this notice removed.  DESCRIPTI
ARRA Characterization and Treatment of the Scarred Vocal Fold
We propose to dramatically revise our research software to fully implement internet capability, improve “user-friendliness,” expand the training modules, and address known issues with the current software. Ultimately, we intend to develop a
Effects of Training on Adult Cochlear Implant Users
This is an application for an administrative supplement in response to NOT-OD-09-056, title: Accelerating the Science, title code: ACC to the NIDCD. In this supplement, we aim to accelerate the parent grant through: 1) recruiting technical staf
Innate Immunity in Otitis Media Pathogenesis
The purpose of the supplement is to fund two part-time undergraduate research assistants and purchase supplies to conduct studies of neuronal circuitry in the octopus region of the PVCN. Making brain sections and learning the method of insertin
Transient Expression of Cholinergic Markers in the PVCN
Our senses of hearing and balance depend on the intricate three-dimensional structure of the inner ear.  The inner ear has a coiled cochlea for hearing as well as three hollow canals oriented with the three dimensions of space, a system that is
Cellular and Molecular Mechanisms of Ear Morphogenesis
The purpose of this supplement is to add technical staff that will accelerate the pace of research outlined in the parent R01 'Sequencing and Initiation in Speech Production.' The primary aim of the parent grant is to develop and experimentally
Sequencing and Initiation in Speech Production
We are currently in the second year of a five-year R01 grant (DC007695), titled 'Development of the Calyx of Held'.  In this competing revision, we propose to extend the scope of and implement new technologies for our investigation of neural ci
Proper perception and behavioral response to the environment by humans is essential for our health and well-being. Our understanding of sensory physiology and sensory-driven behavior has greatly benefited from the surprising conservation of mec
Response of drosophila to pheromones and food stimuli
Dartmouth College Office of Sponsored Projects
Speech perception is a process of mapping continuous detail in the acoustic signal onto discrete units of meaning like words. Given the variability in the signal and speed at which it arrives, the system must cope with a great deal of variation
Lexical Integration of Continuous Acoustic Detail: Normal and Impaired Listeners
The ARRA Administrative Supplemental award proposed to hire new staff to accelerate both the morphological and physiological components of the prime award, that of studying the mechanism(s) of synaptic transmission between the type I hair cell
SYNAPTIC DETERMINANTS OF VESTIBULAR AFFERENT DYNAMICS
Title:  ?Neural Networks for Speech Perception in Noise?  Thirty million Americans with hearing loss struggle daily to understand speech in noisy environments.  A neuroscientific understanding of this problem could improve diagnosis and treatme
Subproject for Institution # 016415: Neural Networks for Speech Perception in Noise
University of California, Davis  Ctr for Mind and Brain
Under this supplement application we propose to purchase and use new equipment to control the motion devices used to assay prosthesis effectiveness.
ARRA-Vestibular Prosthesis in a Vestibulopathic Model
This supplement application is requesting funding to construct an EEG lab at the main facilities in the downtown Chicago campus. This will increase the efficiency in scheduling and recruitment and speed up the research program.
The EQ supplement is to request funds to purchase three pieces of data acquisition equipment (Bak electronics for single unit recording, CED device for high speed data acquisition and Digitimer D360 to record 8-channel event-evoked potentials).
Multiplicative Computation in the Vestibulo-ocular Reflex (VOR)
This proposal requested funding for two pieces of equipment, a cryostat and an RT-PCR system.  The cryostat is necessary in our exploration of the molecular bases of developmental interactions between axons and glial cells that are critical for
GLIAL AND AXONAL INTERACTIONS MEDIATING OLFACTORY RECEPTOR AXON SORTING
This supplement will validate a novel method developed by us to quantify the matrix potential to calcify. This method uses a Fura-2 calibration kit to “extract” Ca2+ from matrix proteins to better test the hypothesis that Oc90 can lead to a
NTHI Immunity in Young Children (Summer supplement):  The parent grant seeks to understand the pathogenesis of Nontypable Haemophilus influenzae (NTHi), one of the major etiological agents of acute otitis media (AOM), which has very high morbid
Effect of cytokines in chronic rhinosinsusitis on olfactory neuron function: The purpose of the parent grant is to study the mechanism of olfactory loss in patients with chronic rhinosinusitis (CRS). The loss of the sense of smell is a common s
This application is in response to Notice Number NOT-OD-09-058, Notice Title: NIH Announces the Availability of Recovery Act Funds for Competitive Revision Applications. The parent project investigates the development of bimodal bilingualism b
The goal of this project is to support students who will work on determining the physiological properties of the olfactory sensory neurons and to determine aberrant axonal targets in CNGA2 and TRPM5 knockout mice.
Intraspecific Chemosignals in the Main Olfactory
One cognitive function often taken for granted is the ability to maintain a sense of direction and location while moving about in the environment. This awareness is essential for getting around and functioning normally in the world. When our se
Motor, Vestibular, and Mnemonic Interactions in Directional Heading Perceptions
We received funds to enable hiring of a University of California (UCSD) and a Harvard undergraduate student (both US citizens) for full time summer research experience.  One student has been working part time in my lab, unpaid, for course credi
Identification of the Ligands and Sensory Neurons That Mediate Pheromone Behavior
Manufacture multisite silicon substrate neural probes fabricated by Bosch process deep reactive ion etching.  The probes will be used to help wiith reserarch of a neural prosthesis device to restore function of the cochlear nucleus nerve in the
Technology for an advanced cochlear nucleus auditory prosthesis
We have recently identified a novel protein secretion pathway (proposed to be a Type IX Secretion System; T9SS) employed by periodontopathogens, including Porphyromonas gingivalis, Prevotella intermedia, and Tannerella forsythia to secrete a
ARRA Bacterial Proteases in Periodontal Disease
Sensory representations within the thalamocortical loop (TCL) are dynamically modulated constructs that emerge from the asynchronous convergence of multiple ascending and descending afferents. Also, tactile neuronal responses in S1 layers diffe
TRIGEMINAL SYSTEM PLASTICITY DURING ACTIVE EXPLORATION
IDIQ Contrat for A-E Services to perform ALTA Survey for the New Courthouse located in Bakersfield, CA.
Parsons is under contract through the General Services Administration to perform Construction Management services throughout the design and construction of the Otay Mesa Land Port of Entry Expansion & Modernization Project in San Diego, Califor
RECOVERY-NEPA FOR ARRA PROJECTS AT MALHEUR NATIONAL WILDLIFE REFUGE
Support to the NETL for review of NEPA documentation for the Office of Fossil Energy.  The objective of this effort is to obtain support to asist the Department of Energy's National Energy Technology Laboratory (NETL) in complying with the Nati
Provide the services of a Recovery - ARRA Technical Coordinator to support DOE-SR Recovery Act Project Manager.  Support includes technical and administrative support including reporting assistance, projecct tracking, analysis and evaluation.
Preparation for Data Center Construction Project.  Scope of work modified 9/25/09 to include an additional 7 borings for the relocation of the Army Reserve garage/storage building.  Other services include soil sampling, piezometer installation
Delivery Order 958 issued by the Environmental Protection Agency, Region 9.  The purpose of this delivery order is to obligate $708,837.00 for implementation of Recovery-ARRA's Green Project Reserve Requirements.  The period of performance is f
Review Environmental Report for Boulder Water Project in accordance with RUS Bulletin 1794A-602 included with the projects.
Provide support to the DOE-EM ARRA Team in defining, establishing, implementing, and tracking the projects funded by the Recovery Act.
The  Social Security AdministrationSSA (SSA) awarded a contract to Strategic e-Business Solutions to provide consulting services to provide personnel with the skill sets required to independently evaluate the SSA's process for selecting the rep
This work is in support of the energy conservation and sustainability measures to be implemented as part of the American Recovery and Reinvestment Act of 2009. This stage is for a study to determine both low-cost control system modifications an
HNTB DISTRICT OF COLUMBIA ARCHITECTURE, P.C.
The purpose of this modification is to: 1)  ADD funding for Architect/Engineering Design Services on Phase 2 of the Mary E. Switzer Building Modernization Project in Washington, DC.  2)  INCORPORATE the attached mandated American Recovery and R
Architectural and Engineering (Mechanical, Electrical, Plumbing) / Design Plans, Cost Estimate and Specifications for Lafayette Modernization Washington, DC.  Construction Management.
ARRA MAIN STATE PHASE 1C DESIGN and COMMISSIONING Construction Management Services for the Design of Phase 1C Demolition, Abatement and Construction of theHarry S Truman Building(US Department of State Headquarters). Jacobs will conduct design
The overall purpose of this award is to provide additional security assistance support to implement and maintain the information security program within the division. To assist in the additional requirement to process Federal and Contractors in
RECOVERY - CM SERVICES FOR OLYM, ELWHA HEIGHTS WATERLINE OLYM 005375
Add additional Independent Validation and Verification Services. Reviews of the Phase I 2009 financial statement reestimate models.
Booz Allen Hamilton and Subcontractor DRT Strategies, Inc., a small woman-owned business, provide comprehensive program management and technical support services to support worldwide deployment of the USAID's Global Acquisition and Assistance p
Chairs were purchased to equip the on-site COBRA Subsidy Denial Intake Center
Office Furniture (except Wood) Manufacturing
Provide support to create, test, and put in production the Social Security Online Accounting and Reporting System (SSOARS).
The FCC tasked Computech with supporting the DTV 2.0 transition initiative, including the development of a redesigned website, providing statistical analysis and reporting, and delivering ongoing support and maintenance from April 1, 2009 th
Appsential LLC, was expected to provide and support IT improvements in performance, quality, timeliness, and efficiency of services provided by the DOE iManage Program and individual iManage systems. Appsential LLC, was expected to provide IT c
Award was for the purchase of information technology commercial items to improve agency operations or to fulfill agency requirements.  Deliverables detailed elsewhere in this report.
Firm Fixed Price task order for CPUs, Video Cards and monitors to be provided as GFE for recover act support services
PRINCIPAL ENGINEER/ANALYST TO LEAD EFFORT TO DEFINE NDAR DATA DICTIONARY; TRAIN INVESTIGATORS TAKING OVER THIS FUNCTION; HELP TO STANDARDIZE PROCESS/PROCEDURE FOR QA/QC OF EXPECTED RAPID INCREASE THROUGH ARRA OF DATA COMING INTO NDAR.
A system enhancement to GAPS and e-Grants/e-Application is needed to support the new requirements resulting from stimulus funds appropriated for the Impact Aid construction program.  This enhancement will allow designated applicants to apply fo
Database Administrator Contract Support for BCRS's Scholarship and Loan Programs:  The purpose of this contract is to provide database administration, maintenance and end-user support, and server support to the end-users for the systems and app
This project is a modification of existing task #FB7507002T3.  The purpose of this task is to perform similar services for the existing staff, but for internal IHS projects that are designated as ARRA tasks.  The requirements are included in th
). The 41-acre site contains archeological sites previously identified by the College of William and Mary's Center for Archaeological Research. Construction of improvements to the Glasshouse Parking Lot and of three new trails will provide link
Through education and training, enhance the Native American Youth s future endeavors.
Commercial and Industrial Machinery and Equipment (except Automotive and Electronic) Repair and Maintenance
The funding is provided to allow for Native American/Alaska Natives to be trained as Plumber and Pipe Fitters.  The Direct Entry Pipe Fitter training is a program that provides successful graduates an opportunity to enter into a five year appre
The funds must be used in accordance with the following: a) Provisions of the Child Care Development Block Grant (CCDBG) Act of 1990, as amended; b) Provisions of the current approved tribal plan, including all approved amendments or revisions;
DHHS Discretionary Child Care Development ARRA Funds.
Provide youth with a comprehensive array of services to better prepare them for a successful transition to the workforce.
Cherokee Nation Supplemental Youth Employment Program
The Red Lake Band of Chippewa Indians received an additional $151,441.00 for the child care program.  These funds were used to assist the families and providers by increasing and maintaining quality activities on health and safety, including a
Department of Labor's Workforce Investment Act Supplemental Youth Services Funds
Improve teaching and learning for students most at risk of failing to meet state academic achievement standards. Further, the purpose of the award is to increase student achievement in reading, writing and mathematics by providing professional
Title I Part A Improving Basic Programs operated by local educational agencies.
replacement and repair of indian schools
539-(Loan Only)Waste Disposal Only-09/10 Stimulus
Calle Guadalupe: I-10 to Tempe City Limits
PKIDs Communications Made Easy program will provide training, consultation, and technical assistance to health departments and immunization coalitions in the areas of communications, social marketing and program implementation, and will create
American Recovery and Reinvestment Act (ARRA), Partnerships to Address Immunization Training and Information Needs of Health Department Staff, Coalitions, Nurses, and Medical Residents
Hot mix asphalt base crushing and shaping, resurfacing, trenching and aggregate shoulders
Hot mix asphalt base crush and shape, hot mix asphalt, resurfacing, trenching, ditching and aggregate shoulders
Function and Form Outcomes in Infant Cleft Lip Surgery-ARRA  This application is in response to NOT-OD-09-058, titled “NIH announces the availability of Recovery Act Funds for Competitive Revision Applications”.  The goal of this applicatio
Function and Form Outcomes in Infant Cleft Lip Surgery-ARRA
This grant is an ARRA administrative supplement to 2-R01-DE016148 (Extending the Phenotype of Nonsyndromic Orofacial Clefts).  This supplement adds a new collaboration that will add facial movement studies to the project.   Through this new col
Extending the Phenotype of Nonsyndromic Orofacial Clefts
through 1) the establishment of a new collaboration and 2) by providing research employment opportunities.  This proposal will enhance currently funded activities through collaboration with (Emmanuel College) and the utilization of the quartz
MATRIX PROTEIN REGULATION OF ENAMEL MINERAL FORMATION
The scope of the original application was to characterize the hemin/iron uptake mechanisms in Porphyromonas gingivalis with an emphasis on the examination of the regulation mechanisms as well as the analysis of the components of the hmu operon.
Small non-coding RNAs in Porphyromonas gingivalis
The goal for the parent R01 was to investigate the effect of antiretroviral therapy (ART) on the life cycle of oral HPV infections in different types oral epithelium. Our hypothesis was that ART affects the host tissue and/or the natural histor
ART ON ORAL TISSUE GROWTH, FUNCTION, AND HPV INFECTIONS
This administrative supplement is to purchase a dissecting microscope with imaging functionality. This instrument will be used to obtain consistent high quality preparations to be used in Specific Aim 2 of the parent proposal.  The microscope w
STEM CELL BASED THERAPY FOR REGENERATIVE ENDODONTICS
The development of dentition involves a complex series of epithelial-mesenchymal signaling interactions. It is not surprising that such a process is prone to disturbances which then manifest as congenital tooth agenesis in up to 10% of the popu
Signaling Mechanisms in Early Tooth Development
This administrative supplement will satisfy the requirements of the program in that the additional personnel and scientific activities performed accelerates the tempo of scientific research in achieving specific aims and advance the objective o
Autoregulation of Glomerular Filtration Rate
Summer experience for high school science teacher and undergraduate student considering career in research.  Worked on studies funded by primary grant.  They participated in whole animal research, didactic lectures related to scientific method,
QUANTITATIVE STUDIES OF URINARY BLADDER SENSATION-SUPPLEMENTAL FUNDS
Amerindians in Chile likely migrated from Asia thousands of years ago, and East Asian strains of H. pylori produce a more pathogenic CagA motif than European strains.  A substantial portion of Amerindians live in isolated, relatively less hygie
IMMUNOBIOLOGY AND PREVENTION OF H. PYLORI DISEASE
The molecular basis for the gene specific effects of butyrate remains poorly defined. Butyrate's major known function involves inhibition of histone deacetylases (HDACs) resulting in increased acetylation. In addition to histone acetylation, it
MECHANISMS OF GASTROINTESTIONAL GROWTH & TRANSFORMATION
Loss of function mutations of the heparan sulfate proteoglycan gene glypican-3 (GPC3), causes an Xlinked disorder in humans known as Simpson Golabi Behmel syndrome (SGBS), a disorder associated with both pre- and postnatal overgrowth, a predisp
PATHOBIOCHEMISTRY OF PROTEOGLYCANS IN DEVELOPMENT
The parent application is focused on determining whether the homeodomain protein Cux1 is a downstream effector of the Notch signaling pathway. Cux1 is the murine homologue of the Drosophila gene Cut. Mammalian Cut proteins function as cell-cycl
Cux-1 and Cell Cycle Regulation in Kidney Development
Amongst the greatest risks to human public health is the possibility of large outbreaks of viruses or antibioticresistant bacteria (natural or engineered) occurring with speeds that would not allow the development and timely administration of p
NEW AIM FOR FLAGELIN-INDUCED GUT EPITHELIAL CHEMOKINE SE
Normal regulation of insulin gene transcription by glucose is essential for the maintenance of glucose homeostasis, and requires the beta-cell specific transcription factors Pdx-1, MafA and NeuroD1. However the exact mechanism(s) by which gluco
Histone Acetylation and Insulin Gene Expression
The present supplement application seeks support for summer research experiences at The Scripps Research Institute for two talented high school interns in the San Diego area. The work to be performed by the interns is directly relevant to the s
Urocortins, Brain CRF2 Receptors and Energy Balance
To achieve normal growth, development, and quality of life, individuals must maintain adequate intake of nutrition and be free from prolonged metabolic derangement. Unfortunately, people affected with either acute or chronic diseases often show
Diabetes and congestive heart failure are diseases that have been associated with defects in the handling of salt and water by the kidney. Common in individuals with these disorders are elevated circulating levels of vasopressin, the peptide ho
Role of Vasopressin in Regulating Renal Medullary Gene Expression
This grant provides equipment.   We have purchased a cryostat and submitted the paperwork to purchase a microscope as requested in the proposal.   We requested funds to purchase the following three equipment items, which are necessary to perfor
Genetic analysis of Pea3 transcription factors and kidney development
Summer Educator Award. This administrative supplement request focuses on the regulation of virulence factors by intracellular NAD+ concentration. We have shown that virulence associated adhesin genes are transcriptionally induced in response to
PATHOGENESIS OF CANDIDA GLABRATA IN THE URINARY TRACT
The goals of the parent grant are to determine the function(s) of P2Y receptors and downstream cytosolic Ca2+ signals in hepatic stellate cell (HSC) function. HSC are important mediators of liver fibrosis, but their regulation is only partially
Regulation of Hepatic Stellate Cells by Extracellular Nucleotides
Zetia (Ezetimibe) inhibits cholesterol absorption via inhibition of NPC1-L1 mediated cholesterol transport pathway(s) in the enterocytes. We demonstrated that CD36 also plays a role in cholesterol absorption. It has also been demonstrated that
Functional & Molecular Study of Intestinal Cholesterol Transporters & Absorption
The Oroboros Oxygraph-2K that will be purchased with the supplemental funds will provide the addition of high-resolution respirometry measurements of mitochondria function in human biopsy samples obtained in the parent project.
Physical Activity Following Surgery-Induced Weight Loss
Obesity and overweight affects most Americans, but there are some who resist obesity, just as some animals resist obesity. Animal and human studies indicate that spontaneous physical activity (SPA), which generates nonexercise activity thermoge
Spontaneous physical activity in obesity
. The parent award is funding the development and testing of a culturally sensitive educational video and financial intervention to improve patients and families consideration of Live Kidney Donation/Transplant as a treatment option for kidney
INFORMATION AND FINANCIAL INTERVENTIONS FOR KIDNEY DONATION IN AFRICAN AMERICANS
Our studies will provide important animal models and biochemical data to further understand the function of testis-specific protein, Y-encoded-like 1 (TSPYL1) and fetal gamma inducing factor (FGIF) proteins in up-regulating gamma-globin gene ex
Little is known about the developmental mechanisms that determine  kidney size and nephron number.  Two major renal cell lineages are collecting ducts, which derive from ureteric bud (UB), and nephron epithelia, which derive from metanephric me
Genetic Control of Ureter and Kidney Development
Congenital defects characterized by impaired urine flow from the kidney into the lower urinary tract are detected in 0.5% of fetuses by antenatal screening and if persistent, can lead to permanent renal damage.  Despite the high incidence and m
ARRA - Nitric Oxide-Releasing Glucose Biosensors  To fully realize our goal of understanding the influence of nitric oxide release and duration on improved tissue biocompatibility (and ultimate the fabrication and characterization of a nitric o
ARRA - Nitric Oxide-Releasing Glucose Biosensors
The goal of this research is to develop and clinically implement a new method of quickly and reversibly blocking the conduction of action potentials in peripheral nerve. In our currently funded project, we have demonstrated that high frequency
A Novel Waveform for Electrical Nerve Conduction Block
We are requesting one year's support to retain a post-doctoral research fellow under the American Recovery and Reinvestment Act (ARRA) Administrative Supplement to parent grant R01-EB002834. This capable young scientist has served one year in t
5-D Image Guided Cardiac Ablation Therapy.
The long-term objective of R01 EB2991 is to develop new drug delivery systems for biomolecular drugs that must reach intracellular targets for efficacy.  The grant is focused on developing and optimizing pH-responsive carriers for anti-neoplast
Biofunctional Polymers for Intracellular Drug Delivery
Antagonists used for positron emission tomographic (PET) studies of dopamine D2/D3 receptors do not distinguish between the high-affinity (HA) and low-affinity (LA) states of the receptors. We and others have now accomplished imaging only the H
Dopamine D2/D3 Receptor Agonists for PET Imaging
NOT-OD-09-060 (Crawford, Neil) Admin. Suppl. Notice for Students and Science Educators under the Recovery Act
A Computerized Planning Tool for Spine Surgery
The objectives of the parent grant EB 006521 are to use a combination of theory, nanofabrication and spectroscopy to develop defined nanostructures which result in enhanced and/or directional fluorescence from surface-bound fluorophores. These
), promoted by expression of the pancreatic transcription factor PDX-1. We now propose to produce neo-islets from human and non-human primate (NHP) AFS cells. To efficiently generate insulin producing cells, we will optimize delivery of a plasm
Insulin Producing Cells from Amniotic Stem Cells for Diabetes Therapy
The summer research experiences for undergraduates will provide numerous avenues to encourage students to pursue research careers in health-related sciences. Opportunities include project and career mentoring, lab meetings, journal clubs, and s
ULTRASOUND TECHNOLOGIES FOR TISSUE ENGINEERING
The primary goal of this award is to study magnetic forces on electric currents in biological tissue, and to analyze and develop new imaging techniques that use these 'magneto-acoustic' effects. In the last two decades, many researchers have pr
This application is a supplement for NIEHS R01 ES003456, which has been continuously funded for over 24 years. This grant currently funds work to develop fusion proteins which target DNA repair enzymes to mitochondria in an effort to enhance th
ENVIRONMENTAL BETA CELL TOXINS-MECHANISMS OF ACTION
Many environmental toxins are oxidants. Proteins, which are major targets of oxidative modification, loose function/activity and must be proteolyticaly degraded or they will aggregate, and form cross-linked cellular inclusion bodies. In previou
Oxygen Radical Toxicity and Protein Degradation
The capacity of modest inflammation to potentiate hepatotoxic responses to drugs (e.g., ranitidine) and other xenobiotic agents has been characterized in several animal models. A common finding is that both neutrophils (PMNs) and hemostasis wit
As a major detoxicating enzyme in human liver, hydroxysteroid sulfotransferase (nomenclature: SULT2A is hydroxysteroid sulfotransferase; SULT2A1 is human SULT2A) catalyzes the sulfonation of biologically important endogenous and xenobiotic subs
SULFOTRANSFERASE EXPRESSION: IMPLICATIONS OF TOXICITY
The objective of this study is to elucidate the mechanism by which testosterone inhibits spermatogonial differentiation after toxicant exposure of rats. Radiation will be used as a model toxicant in most studies and the relevance to chemical to
ACTIVATION OF SPERMATOGENIC RECOVERY AFTER TOXIC INSULT
Our working hypothesis in the parent grant was that inorganic arsenic (iAs) disrupts gene activation from steroid hormone-regulated gene promoters by changing patterns of histone modification. Our goal was to identify mechanisms disrupted by iA
Arsenic, Histone Modification, and Transcription
The Pharmacoxtoxicology of Treichloroethylene Metabolites Study Specific Aims:                                                                            For several years we have researched the kinetics, metabolism and human toxicology of dich
The proposed supplement to the ongoing study of developmental pesticide exposure in ADHD is designed to support a minority graduate student, Ms. Ashley Green, that has been working on the project. Ms. Green is performing research on epigenetic
Mechanisms of Pesticide-Induced Neurobehavioral Deficits:  Relevance to ADHA
Persistent organic pollutants (POPs), such as polychlorinated biphenyls (PCBs), chlorobenzenes and dioxins remain an environmental health threat.  New and innovative ways of detoxifying these compounds removing them from the environment are nee
Integrating Microbial Biostimulation and Electrolytic Aeration to Degrade POPs (Administrative Supplement)
While the specific aims of this grant have not changed, the experiments during this first year have revealed that the level and method of BPA dose administration should be altered to better simulate the free BPA levels that are now known to occ
Subproject for Institution # 07-004128: Effects of Fetal Bisphenol A Exposure on Oogenesis in Primates
The proposed studies will test specific hypotheses about the mechanism and the role of Rho GTPases in the differential regulation of corneal epithelial cell cycle progression (proliferation) and corneal stromal cell activation that are critical
This supplement provides project support, both for a postdoctoral scientist and equipment, to accelerate the pace of the research.  Disorders of the visual nervous system are a major cause of visual disability, and many disorders affect parts o
The overall objective of this ARRA-funded project is to understand how ion channels determine the contribution of retinal ganglion cells to vision. Experiments are designed to identify and analyze mechanisms of ion channel regulation and neurot
Subproject for Institution # 880909: Pharmacology and Physiology of Retinal Ganglion Cells
Glaucoma remains a major blinding disease affecting over 66 million persons worldwide. This project has focused on the molecular mechanism(s) by which laser trabeculoplasty (LTP) ameliorates the elevated intraocular pressure (IOP) associated wi
BIOLOGY OF TRABECULAR RESPONSE TO LASER TRABECULOPLASTY
The overall goal of the currently active NEI-funded parent project is to determine the causes and consequences of spatiotemporal contrast processing deficits in individuals with retinitis pigmentosa (RP), a group of night-blinding retinal degen
Visual Dysfunction in Retinal Degenerations
Our purpose in carrying out these studies is to understand the molecular causes of and to improve treatments for recurrent corneal erosions and corneal epithelial stem cell deficiency. Trauma-induced recurrent erosions to the cornea cause pain
Molecular Aspects of Corneal Epithelial Migration
The purpose of this administrative supplement is to replace two pieces of equipment and to provide a salary for a laboratory assistant. The equipment includes a cryostat and a freezer, both central components of our research laboratory supporti
DISPERSION PATTERNS FOR RETINAL NEUROBLASTS
Glaucoma is a disease of the visual system often characterized by pressure-induced damage to the optic nerve. This results not only in a loss of ganglion cells from the retina, but also degeneration of their target neurons in the lateral genicu
STRUCTURE-FUNCTION OF THE RETINA WITH NEUROPROTECTION
The specific aims of the grant are to determine the role of visual experience in the development of the retinotectal system. We have used in VIVO 2 photon imaging and electrophysiology to address these questions and now propose to significantly
Activity Dependent Control of Visual System Development
Success of corneal transplant is dependent on high corneal endothelial (CE) cell density maintained immediately after surgery and thereafter. CE cells die either by acute necrosis, which initiates detrimental inflammatory responses, or by a slo
Neurotrophic Factor Modulation of Corneal Endothelium
This is a request for an administrative supplement to RO1 EY11733 (NEI/NIH). The goals of the parent grant are to determine the effects of aging and oxidative damage in the development of age-related and x-ray caused cataracts. Under the reques
Dietary and Genetic Control  of ROS Damage to the Lens
The ocular motor system is arguably the best understood mammalian motor system. However, the extraocular muscles, its effector arms, remain somewhat of a black box. From a peculiar phenotype and extreme functional profile, to a disparate respon
Determinants of Extraocular Muscle Function
We are requesting supplemental funds to employ a new graduate student to carry out studies that will accelerate our scientific progress on our funded proposal. The overall goal of the funded proposal is to determine whether the Muller glia of t
Our long-term research goal is to understand oculomotor development and the pathogenesis of congenital ocular motor diseases. We address this goal through genetic and neurodevelopmental studies of complex congenital eye movement disorders and t
Genetic and anatomic basis of the fibrosis syndromes
We are addressing the physiology of aqueous humor outflow regulation, concentratingon cell volume regulatory transporters and adenosine receptors of Schlemms canal,juxtacanalicular and trabecular meshwork cells, and on the potential role of cel
AQUEOUS HUMOR OUTFLOW CONTROL AND INTRAOCULAR PRESSURE
Visual scenes contain too much information to be perceived in a single glance.  Natural visual tasks – reading, search, evaluating a scene – depend critically on sequential examination by saccadic eye movements and shifts of attention.  Sac
The overarching study was initiated because the adverse neural consequences of abnormal vision have been well researched, but under-detection of risk factors for amblyopia is still common.  Gaps in screening in the medical home are due to child
MULTI-MODAL PHYSICIAN INTERVENTION TO DETECT AMBLYOPIA
Impairments in visual-auditory integration impact numerous aspects of human health, ranging from communication and language to attention and movements in a complicated environment. Previously, such deficits were believed to involve higher brain
Our goal is to acquire an  MR-compatible visual display set-up that has an integrated eye-tracker. Our  experiments require mapping brain systems that mediate attention and visual  short-term memory and how these systems change as a function of
Corneal wound healing without scarring regenerates corneal transparency. Corneas that heal with scarring have opacities and obstructed vision. Thus, understanding the pathways that influence regenerative rather than fibrotic healing is an essen
CORNEAL REPAIR: UPA AND EXTRACELLULAR MATRIX
Quarterly Report for ARRA Supplement Sensory-Motor Control of the Binocular Near Response PI: Clifton M. Schor   Overall purpose and expected outcomes, or results of the contract:  The supplement investigates the impact of neural deblurring on
Sensory-Motor Control of the Binocular Near Response
DESCRIPTION (provided by applicant): Avascularity of the cornea is necessary for optical transparency in the visual axis. Vision-threatening corneal angiogenesis can be caused by diseases, aging, infection, or trauma. The basis of the cornea's
THE ROLE OF SFLT IN CORNEAL AVASCULARITY
We propose the following specific aims:  1) To access how the TLR-mediated signaling pathways are modulated by the IRAK family of proteins and Pik/AKT and what roles they play in acquiring tolerance phenotype in HCECs. This will be achieved by
MACHANISMS OF FLAGELLIN INDUCED PROTECTION AGAINST BACTERIAL KERATITIS
Hot mix asphalt cold milling and resurfacing, minor curb and gutter, sidewalk, guardrail and storm sewer work.
Concrete restoration, diamond grinding, crack sealing and ramp extension
Hot mix asphalt cold milling pavement and resurfacing
Hot mix asphalt base crushing and shaping, resurfacing, trenching and aggregate shoulders.
Hot mix asphalt paving, aggregate base conditioning, aggregate shoulders and slope restoration
Hot mix asphalt overlay and pavement marking
Pavement removal, concrete pavement, concrete pavement repair, guardrail replacement, hot mix asphalt approach
Pavement removal, concrete pavement. concrete pavement repairs, cold mill hot mix asphalt & resurface & earthwork
Hot mix asphalt cold milling and resurfacing, concrete ramps and pavement markings
Hot mixed asphalt cold milling and resurfacing
Overband crack fill, chip seal, approach work, shoulder and pavement repairs
Hot mix asphalt cold milling and overlay, concrete pavement repairs, aggregate shoulders, guardrail
Aggregate base, hot mix asphalt base crushing
Hot mix asphalt resurfacing, cold milling
Hot mix asphalt resurfacing and aggregate shoulders work.
Hot mix asphalt resurfacing including ...
Hot mix asphalt resurface and sidewalk improvements
Street realignment under the Blue Water Bridge to secure piers
Hot mix asphalt intersection construction, machine grading, aggregate base, curb and gutter and slope restoration
Deck replacement, structural steel and substructure repair painting, pedestrian fence and utility relocation
Deck patching, painting, substructure and slope repair, concrete coating, joint replacement, pedestrian fence
Deck replacement, structural steel and substructure replacement, painting utility relocation, pin and hanger
Cold milling hot mix asphalt pavement and hot mix asphalt resurfacing
Cold milling hot mix asphalt pavement and resurfacing
hot mix asphalt crack treatment roadbed, warranty
Providing Design Build services for 12 Environmental Sensor Station sites
HIT Implementation Grant - Innovations The HIT Innovations project is designed to improve the quality of clinical care by implementing a Point-of-Care system to assist in clinical decision making.  The software system is called Cielo Clinic.  C
OREGON COMMUNITY HEALTH INFORMATION NETWORK, INC
The OCHIN Transforming Care Quality (TCQ) project seeks to positively impact the health status of patients with diabetes who are served by five different community health center organizations located in Oregon and California.   This project wil
This grant supports the development of a risk stratification protocol that uses data from an electronic health record system to rank patients according to their risk for developing diabetes .  The protocol has been used to identify patients at
Assist in operating statewide comprehensive, coordinated, effective, efficient and accountable programs of vocational rehabilitation, which are an integral part of a statewide workforce investment system; and designed to assess, plan, develop,
Vocational Rehabilitation Services to States, Recovery Act
EDUCATION AND SERVICES FOR THE BLIND, CONNECTICUT BOARD OF
Assist in operating statewide comprehensive,coordinated,effective,efficient and accountable programs of vocational rehabilitation,which are an integral part of a statewide workforce investment system;and designed to assess plan,develop,and prov
Vocational Rehabilitation Services to States,Recovery Act
Assist in operating statewide comprehensive, coordinated, effective, efficient and accountable program of vocational rehabiliation which are an integral part of a statewide workforce investment system; and designed to assess,plan, develop, and
KENTUCKY EDUCATION AND WORK FORCE DEVELOPMENT CABINET
Assist in operating statewide comprehensive, coordinated, effective, efficient and accountable programs of vocational rehabilitation, which are an integral part of a statewide workforce investment system; and designed to assess, plan, develope,
Assist in operating statewide comprehensive, coordinated, effective, efficient and accountable programs of vocational rehabilitation, which are an integral part of a statewide workforce investment system, and designed to assess, plan, develop,
The State of Tennessee's Vocational Rehabilitation (VR) State Grants program grant award under the American Recovery and Reinvestment Act of 2009 (ARRA).  These funds are provided in accordance with section 807 of the ARRA, which allows the Sec
BLIND AND VISION IMPAIRED, VIRGINIA DEPARTMENT FOR THE
SERVICES FOR THE BLIND, WASHINGTON STATE DEPARTMENT OF
Assist States in providing special education and related services to children with disabilities in accordance with Part B of the IDEA.
Grants to States for the Education of Children with Disabilities
Assist States in providing special education and related services to children with disabilities in accordance with Part B of the IDEA. All remaining funds are the result of subrecipients not fully expending their awards. No more funds will be e
CONNECTICUT STATE DEPARTMENT OF EDUCATION
Assist states in providing special education and related services to children with disabilities in accordance with Part B of the Individuals with Disabilities Education Act (IDEA).
Assist states in providing special education and related services to children with disabilities in accordance with Part B of the IDEA.
Funds are used for special education staff, for training of staff for special education, for the purchase of transportation as per IEP which includes ADA compliant modifications/alterations, for construction which includes ADA compliant accessi
Grants to States for the  Education of Children with Disabilities
PUBLIC INSTRUCTION, NORTH CAROLINA DEPARTMENT OF
Grants to states for the Education of Children with Disabilities
Assist States in providing special education and related services to children with disabilities in accordance with Part B of the IDEA
Assist States to make available special education and related services for children with disabilities age 3 through 5 years, and at a State's discretion, to 2 year old children with disabilities who will reach age three during the school year.
Preschool Grants for Children with Disabilities
Assist States to make available special education and related services for children with disabilities age three through five years, and at a State's discretion, to two-year-old children with disabilities who will reach age three during the scho
Assist states to make available special education and related services for children with disabilities age 3 through 5 years, and at a state's discretion, to 2-year-old children with disabilities who will reach age three during the school year.
Assist states to make available special education and related services for children with disabilities age 3 through 5 years, and, at a state's discretion, to 2 year old children with disabilities who will reach age three during the school year.
Assist States in the implementation of a statewide, comprehensive, coordinated, multidisciplinary, interagency system of early intervention services for infants and toddlers with disabilities and their families.
Early Intervention Program for Infants and Toddlers with Disabilities
IDEA Early Intervention Grants for Infants and Toddlers for distribution to Child Development Services regional sites
Individuals with Disabilities Education Act Grants for Infants and Toddlers, Recovery Act
PUBLIC WELFARE, PENNSYLVANIA DEPARTMENT OF
EARLY INTERVENTION PROGRAM FOR INFANTS AND TODDLERS WITH DIS
Early Intervention Program for Infancts and Toddlers with Disabilities
Infants and Families with Disabilities program will create a Data Manager  to document children's information, reporting and monitoring capabilities. This base will be linked to fiscal data and monitoring program through HIE.
A state program to provide independent living services to individuals with significant disabilities, support the operation of centers for independent living and the Statewide Independent Living Council, provide training on the independent livin
State Independent Living Services, Recovery Act
148 Andrew Young International Blvd., N.E.
State Independent Living Services, Recovery Act.
REHABILITATION SERVICES, MISSISSIPPI DEPARTMENT OF
A state program to provide independent living services to individuals with signficant disabilities, support the operation of centers for independent living and the Statewide Independent Living Council, provide training on the independent living
DEAF & HARD OF HEARING COMMISSION NEBRASKA
VOCATIONAL REHABILITATION DIVISION, NEW MEXICO
REHABILITATION SERVICES, WEST VIRGINIA DIVISION OF
State Independent Living Services is a state program to provide independent living services to individuals with significant disabilities, support the operation of centers for independent living and the Statewide Independent Living Council, prov
A state program to provide independent living services to older individuals who are blind, conduct activities that will improve or expand such services and help improve public understanding of the problems of such individuals.
Independent Living - Older/Blind, Recovery Act
A state program to provide independent living services to older individuals who are blind, conduct activities that will expand such services and help improve public understanding of the problems of such individuals.
State Independent Living Services - Older/Blind, Recovery Act
148 Andrew Young Internation  Blvd., N.E.
A state program to provide independent living services to older individuals who are blind, conduct activities that will improve or expand such services and help improve public understandign of the problems of such individuals.
HUMAN SERVICES, NEW JERSEY DEPARTMENT OF
Independent Living  - Older/Blind, Recovery Act
153 HALSEY ST., 6TH FLOOR, P. O. BOX 47017
Energy efficiency upgrades at two Culver City Parks facilties.  Upgrades include, solar panels on the roof, skylights, energy efficient lighting and HVAC, solar lighting for playgrounds/playing fields.
Roof replacements, lighting change outs, heat/air replacements in public buildings, and lighting for First Street Square.
The City of Noblesville, Indiana, will install new LED lighting and equipment to save energy and maintenance costs in downtown Noblesville business areas and in numerous other sections of the city.
Retrofit City of Noblesville street lights with LED lights
Funding will be used for enegy inspection training, increase energy efficiency of certain Town buildings, become a Green Local Government, install electric charging stations for vehicles, and install a bike/pedestrian path.
Energy Efficiency Retrofits. Replacement of HID lighting to energy efficient LED lighting and t-8 lighting. Installation of programmable thermostats.  Replacement to energy effecient hotmwater heaters.  Replace aged HVAC equipment.
EE Conservation Block Grant Program (2004350)
This proposed three year REU site program at the University of Puerto Rico at Mayaguez (UPRM) will provide research experiences for undergraduate students focused in the area of industrial and systems engineering.  Students will be recruited fr
REU SITE: Educating the culturally-sensitive industrial engineer: A complex interdisciplinary systems perspective to global IE issues
The research experiences for undergraduates (REU) Site will support 10 undergraduates - split between the University of Massachusetts Lowell, Northeastern University, and the University of New Hampshire - for 10-week-long research experiences i
REU Site: Incorporating Ethical Decisions into Nanomanufacturing Research
Collaborative Research:  Develop Next Generation unified Framework for Remote Laboratory
Collaborative Research:  Develop Next Generation Unified Framework for Remote Laboratory
This planning grant is to create a process that will shorten the time to degree in Engineering at the bachelor?s level and to improve retention and success for Post 9/11 Veterans.  The School of Engineering will design a system for evaluating m
Soldier to Engineer: Planning VCU's Pathway
The engineering education research award to the Missouri University of Science and Technology wil employ researchers to create an integrated engineering curriculum that emphasizes sustainability and globalization in the context of green manufac
Collaborative Research: Sustainability in Supply Chain Management and Facility Logistics Curriculum
The Southern Region Multi Industry National Emergency Grant provides funds to assist 815 laid off workers from 11 companies in the 3 southern Workforce Investment Regions of the state.  The funds are used to provide re-employment and training s
WIA Dislocated Workers/National Emergency Grant Southern Region Multi-Company Dual Enrollment
WORKFORCE DEVELOPMENT, WISCONSIN DEPARTMENT OF
This project is providing a full array of re-employment services including case management, assessment, career counseling, occupational skills training, relocation assistance, child care and transportation support services and job search assist
On December 15, 2008, Formed Fiber Technologies of Auburn, ME announced they would temporarily lay off 292 workers. Of the 292 workers, 129 were recalled. On February 11, 2009 the Rapid Response Coordinator for the State of Maine received a let
Workforce Investment Act- National Emergency Grants (Formed Fiber Tech)
The purpose of the American Recovery and Reinvestment Act Station Construction Grant is to build or modify existing fire stations in order for departments to enhance their response capability and protect the community they serve from fire and f
The purpose of the FY 2009 ARRA SCG is to create or save jobs in recession-hit areas and achieve other purposes stated in ARRA, and achieve AFG goals of firefighter safety and improved response capability/capacity based on need through the cons
The purpose of the Nurse Faculty Loan Program (NFLP) proposal is to increase the number of qualified nursing faculty by providing loans to nursing students. The University of Pittsburgh School of Nursing enrolls students into Nursing Education
To fund specific work assignments directly related to the clean water and drinking water state revolving fund programs to assist with ARRA implementation and reporting by the states.
EA ENGINEERING, SCIENCE, AND TECHNOLOGY, INC.
Conduct Remedial Action to implement Phases 1A and 2A of the remedial design at the Atlantic Wood Industries Superfund Site in Portsmouth, Virginia.  The scope of this award includes as Phase 1A: Remedy Component 1) excavate contaminated soil a
Implement Remedial Action at the Jacobsville Soil Contamination Site.  Soil remediation of lead contaminated soil in residential area in accordance with the RD.
CDM has been tasked to perform cleanup, or remediation, to address the groundwater contamination at the Lawrence Aviation Industries (LAI) site in the Village of Port Jefferson Station, Town of Brookhaven, Suffolk County, New York. The remedial
and develop Analysis of Brownfield Cleanup Alternative (ABCA) describing cleanup options and cost estimate for cleanup,  This task order is only for a single site (Selma), which was completed as a multi-site requirement under TO4014 file refer
Combined Phase II Environmental and Closure Assessments & UST Removal - Hillsborough County, Florida
Work will consist of conducting a site assessment to determine if underground storage tanks are present and if so, if a fuel release has occurred at the Old Union 76 Station on the Flathead Indian Reservation in Poulson, Montana.  To assess the
Group 10 Enhancement Project (Common St. (SRP), Loyola Ave., St. Peters St.
Group 10 Enhancement Project (Loyola Ave. (SRP), Canal St., US 90)
Jackson Drive, Holke Road to M-78 Highway, Jackson
39th Street Traffic Signal Upgrade, Jackson
Regional Transit (Smart Moves) Implementation Plan, Jackson
Great Streets Demonstration Projects - Labadie
This award with be used to assist persons to secure employment and workforce information by providing a variety of job search assistance and information services without charge to job seekers and to employers seeking qualified individuals to fi
148 Andrew Young International Blvd., N. E.
There were no activities to report since the grant ended June 30, 2011.
Workforce Wagner-Peyser Employment and Reemployment Programs
American Recovery and Reinvestment Act of 2009 funding allocations to supplement PY 2008 Wagner-Peyser Act base allotments add Reemployment Services funding per Training and Employment Guidance letter No. 13-08
Employment Services - Wagner/Peyser, Employment Service Activities and Reemployment Services funded under the Wagner-Peyser Act.
LABOR AND WORKFORCE DEVELOPMENT, NEW JERSEY DEPARTMENT OF
The Employment Services grant is comprised of two parts: Employment Services $3,998,314, and Reemployment Services $6,663,857
Employment and Reemployment Services Activities
Employment Service/Wagner-Peyser State Grants: To provide individuals with a wide range of employment-related services including assessment of skill levels, abilities and aptitudes, career guidance when appropriate, job search workshops, and re
Employment Services Operations:  The overall purpose is to assist participants in our SD Department of Labor local offices to find suitable employment and to provide services which include: job search assistance, skills assessment and labor mar
E-76 (authorization) issued from Caltrans 7/16/09. Asphalt Concrete Overlay.
TRANSCRIPTIONAL CONTROL OF THE MOUSE AA-CRYSTALLIN LOCUS
HISTORICAL EMIGRANT TRAIL, HOOPER CITY PHASE II
SR-190 & SR-210; WASATCH BLVD.; I-215 TO COTTONWOOD CYN.
SIGNAL INTERCONNECT; SALT LAKE COUNTY & LOCAL JURISDICTIONS
US-89; EPHRAIM, MANTI, PANGUITCH MAIN ST. & SNOW COLLEGE LP.
SR-186; FOOTHILL BLVD; SUNNYSIDE AVE TO 1300 EAST
To provide Construction Administration services for Suitland, MD Facilities on an as needed basis in accordance with the Smithsonian Institution's Scope of Work.
NORTHROP GRUMMAN SPACE & MISSION SYSTEMS CORP.
The funding provided via the American Recovery and Reinvestment Act (ARRA) of 2009 will accelerate planned FY10 NPOESS development activities that will contribute to critical path risk reduction for the following projects: 1) C1 Critical Path R
Guided Missile and Space Vehicle Manufacturing
OVERLAY ROADWAYS AND IMPROVE STREET DRAINAGE
E. LOCUST ST-N. DIAMOND ST PRESERVATION (COBURG)
NORTH 10TH ST: CENTRAL AVE-CEDAR AVE PAVING
CRESCENT AVE: GAMEFARM RD-50'W OF SHADOWVIEW (EUG)
INC PED/BIKE SAFETY THRU CONNECTIVITY&IMPRVMTOF EXIST FAC&#59;ARRA FUNDS FOR SIDEWALK CNSTRUCT
FOREST GROVE PED IMPROVEMENTS:19TH AVE-PACIFIC AVE
This project will repair the Visitors Quarters Access Road at the NE corner of KAFB. These improvements include the removal and replacement of the existing asphalt pavement, various concrete and drainage improvements, striping, traffic signage
The primary goal of this project is to construct an office area on the west side of the vehicle barn.  The major work to be accomplished under this task order includes, but is not limited to the following:  (a) Construct addition of approximate
This project will provide for the construction pertaining to:  full-scale replacement or overlay to the existing roof, including but not limited to:  replace flashings, seals, full membrane systems, roof-to-wall transitions, underlayments, stru
Provide architectural & engineering to install/renovate multiple existing buildings for ground source heat pump systems.
Predicting cognitive inconsitency from physical activity and sleep in late-life
The goal of this project is to identify networks within the brain that are involved in attention and memory and evaluate how these networks may change due to normal aging. Differences in the connectivity and functionality of networks subserving
Age Related Changes in the Top-down Modulation of Workin
Independent Living, Older/Blind, Recovery Act
Lauderdale Conty/Ripley Streetscape - Pase III
Road Construction Project - Asphalt overlay located on various IRR routes.
Exterior general maintenance, flowers, shrubs / tree care, weeding, edging and lawn care, repair of sidewalks, parking lot repairs / replacement & repaint parking lot area. Exterior building maintenance, repair / replace doors / windows, repair
BIA Pima Agency Maintenance repairs to buildings & Grounds.
IDS Funding for .50 FTE provider and 1 FTE medical assistant at our newest site called the Irma Colen Health Center. The goal is to provide comprehensive health care to individuals qualifing for services. This clinic is located in an MUA and sp
Palmetto Health Council, Inc. (PHC) is a network of five federally qualified health centers serving the uninsured and underserved populations south of Atlanta and north of Macon, Georgia.   The offices of Palmetto can be found in Fulton, Lamar,
Recovery Act Health Center Cluster program to expand services into two new points of access in Meriwether County, Georgia.
Provide Medical and Dental Services in underserved area.
RECOVERY ACT HEALTH CENTER CLUSTER PROGRAM
for a community health center in the Archer Heights Neighborhood  Goals: To open a new access point to serve the uninsured and low-income population of Archer Heights and Brighton Park.  Importance: Many of the residents of the community area
BEACON CHRISTIAN COMMUNITY HEALTH CENTER
The purpose of the original award was to allow South Central Family Health Center (SCFHC)  to extend its scope of project to the Greater East Los Angeles Community allowing for the formation of a partnership with White Memorial Medical Center a
Family Health Centers of San Diego received a New Access Point grant from the Health Resources and Services Administration to establish a new community health center in Lemon Grove, CA.  By the 3rd year of the Lemon Grove Family Health Centerâ€
The Playa of Ponce Community Health Center (PPCHC) was created by a group of community leaders as a non-profit community health center for the Playa Sector of Ponce, Puerto Rico, in 1971, obtained state and federal IRS 501 (c) (3) tax exemption
Recovery Act Health Center Cluster Program (Public Housing MED Project)
Recovery Act Health Center Cluster Program Major health care needs and barriers to care to be addressed by the project: Target populations suffer high rates of HIV/AIDS, cardiovascular disease and diabetes. Major health care needs are for prima
Northeast Community Clinic (NECC) received $1,300,000 of NAP (New Access Point) funds to increase access to primary care and preventive health services and reduce health status disparities among the target population living and/or working in th
ST. THOMAS COMMUNITY HEALTH CENTER, INC.
to serving and excelling as a medical health provider within the Federally Qualified Health Center program.  The award assists with our overall mission of providing health care to those most in need, our service delivery model is based on iden
Grant Name: New Access Point Grant Purpose: To provide medical services to the indigent and uninsured population in our community. Goals:  The goals of this grant were to become a federal qualified health center and offer comprehensive medical
MOUNT ENTERPRISE COMMUNITY HEALTH CLINIC
Program provides basic assistance for the expansion of services offered to an increased population. Funds awarded support program activites as defined in the scope of project.
BARRIO COMPREHENSIVE FAMILY HEALTH CARE CENTER, INC.
The purpose of this grant is to open a primary care medical facility in San Marcos, TX.
Department of Health and Human Services Health Resources and Services Administration (HRSA)/American Recovery and Reinvestment Act of 2009 (ARRA) - Increase Services to Health Centers
We received the ARRA Increase Services to Health Centers Grant which we utilized to expand healthcare services to uninsured and underinsured residents of Greene County, Mississippi.  Our goal was to increase access by increasing hours and avaib
The IDS funds are being applied to increase health center funding by the addition of personnel costs of 2 FTE new physician providers ( one pediatrician and one internist), their support staff of 1 FTE new nurse, 1  FTE new medical assistant an
ARRA - Increase Services to Health Center
Increase health center staffing and retain current staff positions that were affected by the economic recession.
The purpose of the Increased Demand for Services Grant H8BCS11572 Award is to provide funding to help support the salaries of a .5 FTE Behavioral Health Counselor and a .2 FTE Dentist.  The goals of the project are to increase behavioral health
We are addressing the need for health services within our service communities through a combination of tried-and-true methodologies.  First of all, we are providing greater access through the hiring of two new nurse practitioners.  These provid
The purpose of this award was to provide funds to retain 4.0 FTE positions and add 4.0 FTE positions for increased demand for services.
Increase Services to Health Centers - to retain staff and increase access to health center services
This is an award for increased demand for services for FQHC Kodiak Community Health Center (KCHC).  KCHC will provide the community with 2 half time Outreach/Case Workers to reduce barriers to care and coordinate primary health care and support
for 675 residents of our service area. Our program/arrangement and access line were implemented in mid-August 2009.
ARRA - Increase Services to Health Centers. The projects funded under IDS have been fully implemented; includes the expansion of after hrs care in rural areas, addressing opiate dependency treating with Suboxone, OB/GYN expansion, add?tn of psy
The overall purpose of the Health Resources and Services Administration of the Department of Health and Human Services grant #H8BCS11719 is to increase services to the insured and underserved communities of Los Angeles County. The clinic?s goal
WELSH MOUNTAIN MEDICAL AND DENTAL CENTER
40% of the award is being used to stabilize the Center in absorbing the growth in sliding fee discounts provided to patients.  With a 17% growth in sliding fee utilization by patients and the expectation of 20% of WMMDC patients losing their in
APHCV?s Increased Demand for Services (IDS) Project is focused on increasing access and awareness of available health care services to low-income, monolingual Asians in Los Angeles County. Specifically, this IDS project enabled APHCV to hire a
Increased Demand for Services for Health Centers
These funds are designated to expand pediatric care and ensure continuity of care during periods where there is a provider vacancy due to resignation or non-renewal of contracts. Additional pediatiric care to meet demand helped retain a solo pe
ARRA - INCREASED DEMAND FOR SERVICES TO HEALTH CENTERS.   Goal:  IDS funds are being utilized to increase health center staffing so that direct medical services can be improved, as well as to improve recruitment and retention of health care pro
Family Health Center of Battle Creek (FHC) will sucessfully recruit two additional primary health care providers and three clincal/ancillary support staff.  Provider recruitment will be accomplished through services shared with the Center by th
AARA-Increased Services to Health Centers
Our project type is to ?Increase Health Center Staffing? in order to expand and deliver comprehensive health services to the vulnerable populations in our service areas.  With our IDS award we have created 21 new positions.  Of the 21 new posit
Grant to increase medical staff to meet increased demand from uninsured patients.
Implementation of the IDS medical care retention project will be culturally appropriate and will be made available, assessable, affordable, appropriate, adequate and acceptable to all community members, particularly for individuals, families an
This project addresses the community need by allowing us to recruit and hire a full time psychiatric/Mental Health Nurse Practicitioner. We hired this full time position in August of 2009.  She is building her practice base in our rural and is
Grant Name- Increased Demand for Services (IDS)  Purpose- The IDS grant will allow the Stewart County Community Medical Center (SCCMC) to expand existing dental care for children, initiate an adult dental program, and continue the provision of
).  Prior to this award, JVCHC hours of operation were Monday through Friday, 8:00 am to 5:00 pm, and our medical schedules were filled to capacity.  With this award, we were able to hire an additional nurse practitioner, two in-take workers an
HEALTH CARE FOR THE HOMELESS OF MILWAUKEE INC
ARRA - Increase Services to Health Centers-The project utilizes a model of direct service provision and purchase of service subcontracts to maximize access and services throughout our service area to a population that often lacks access to tran
The purpose of this award is to increase capacity to provide primary care services to low income uninsured whose numbers are increasing due to the economic downturn. The award will support hiring one Pediatrician, one medical support staff and
The grant name is ARRA ? Increase Services to Health Centers ? Increased Demand for Services. The purpose of the grant is to increase the availability of health services at La Clinica de La Raza so that additional community residents can be see
Due to the current status of the economy and high unemployment rate in our community, Alivio Medical Center has seen an increase in the amount of uninsured patients.  With IDS funding Alivio has hired and/or retained healthcare providers to mee
ARRA Increase Health Center Services:   The Increased Demand for Services (IDS) grant purpose is to increase the number of patients served by adding new providers, expanding hours of operations, and/or expanding existing health center services.
Grant Name: Increased Services to Health Centers Purpose: To avoid service reductions resulting from layoffs; to increase employment; and to increase service levels to the extent possible. Goals: to retain and employ staff and provide patient c
IDS Funding was used to increase access to pediatric care for the underserved population in the city of Tulare, California.  IDS funding helped increase the number of pediatric patients seen at the Pediatric Clinic site by adding 2 FTE Pediatri
Grant Number:  H8BCS11872 Community Health Assistance and Advocacy Team (CHAAT)project. The overall goal for the CHAAT program is to improve access to health care services.  The CHAAT program provides access to health care services, patient edu
CHAAT-Community Health Assistance and Advocacy Team
Good, Green, Safe Jobs:  Promoting worker health and safety on ARRA and green job projects The award funds three university-based programs—UCLA-LOSH, UCB-LOHP and the University of Washington—through a supplement to the existing HazMat Trai
WORKER HEALTH AND SAFETY TRAINING COOPERATIVE AGREEMENT
The purpose of this ARRA Administrative Supplement is to plan for the development of a Minority Biospecimens/Biobanking Geographic Management Program (BMaP) hub for Region 6. First, a project coordinator and a graduate student research assistan
ARRA: Administrative Supplement: Comprehensive SDSU/UCSD Cancer Center Partnership
Rehabilitate Runway [Overlay runway] - 12/30
Rehabilitate Runway 10/28 - Phase 2 (6,000'+/- X 150')
Site Investigation, Replacement of Water Lines, Marion, IL.  Task Order No. 301818Y096 is issued for Architect Engineering services consisting of a site investigation to update an existing water plan and to develop a plan for water lines and di
Replacement of Water Lines  at Crab Orchard National Wildlife Refuge
WOODY BIOMASS PROJECT FOR TREE CLEARING, PILING AND/OR CHIPPING, WOODY BIOMASS UTILIZTION RELATED ACTIVIES.
Devils Lake - ND 19 from US 2 to ND 20 (Asphalt Portion only)
Design and reconstruct Runway 12-30 and construct Taxiway J realignment at the Sierra Vista Municipal Airport-Libby Army Airfield.
Runway 12-30 Reconstruction and Taxiway J Realignment
Airport Development.  This project will overlay and reconstruct Runway 1R-19L to repair deteriorating pavement, improve the surrounding drainage system, upgrade the electrical runway and taxiway lighting system, and repaint runway markings to i
Airport Development-The objective of this grant is the rehabilitation of a portion Taxiway E-4 from the edge of the Runway 17L-35R pavement to just west of the runway hold-lines including the shoulders and electrical replacement, and rehabilita
Rehabilitate Taxiway E 4 from Sta.9-46.86 to Sta. 16-20.65, rehabilitate Taxiway E5 from Sta 9+46.29 to Sta 15+97.53
Airport Development - Rehabilitate and reconstruct the aircraft parking apron - Durango-La Plata County Airport, Durango, Colorado. The south one half of the apron had totally failed and created a safety hazard due to the potential of foreign o
Rehabilitation of Taxiway C and related work a the Orlando International Airport.  Taxiway C is a parallel and primary taxiway servicing Runway 18R-36L and Runway 18L-36R. The scope generally includes the resurfacing and/or strengthening of the
Rehabilitation of Taxiway C and Related Development - Phase 3
Rehabilitation of the center portion of Runway 6/24 - 960 feet long  by 150 feet wide - bring the entire runway up to the same length, at Decatur Airport.  Decatur, Illinois
; Whiteside County Airport (SQI) - Rehabilitate South Terminal Apron.
Litchfield Municipal Airport 3LF-3559-ARRA Jacksonville Municipal Airport IJX-3903-ARRA Whiteside County Airport SQI-3910-ARRA
Airport Development - Rehabilitate Runway 13/31 at Smith Field Airport in Fort Wayne, Indiana.
Airport Development. Rehabilitation of the pavements on Runways 01R-19L and 9-27 including associated taxiways and the aircraft enplaning and deplaning aprons of three passenger terminals to extend the useful life of these pavements.
Rehabilitate Runway 01R/19L, Runway 9/27 and Terminal Aprons
Airport Development. The Award funds the rehabilitation and extension of Runway 13/31 at the Manhattan Regional Airport. This work includes the removal of existing 3,800 feet of pavement and replacing it with 5,000 feet of new concrete.  FAA st
Rehabilitate Runway [Reconstruct/extend Runway 13-31] 13/31.
Airport Development- This project will rehabilitate of Runway 9-27 at the Logan International Airport.  The design and milling / paving project which will resurface the asphalt pavement on Runway 9-27.
Airport Development at Detroit Metropolitan Airport (DTW) in Detroit, MI - Rehabilitate Runway 9L/27R
Reconstruct Runway 9L-27R west of Runway 4R-22L (approximately 500' x 150'); Reconstruct Runway 9L-27R between Runways 4R-22L and 3L-21R (approximately 2,700' x 150')
Airport Development: Airport Development at Albert Lea Municipal Airport in Albert Lea, MN - Rehabilitate Runway 4/22
GREAT FALLS INTERNATIONAL AIRPORT AUTHORITY
Rehabilitation of a portion of Taxiway Alpha at the Great Falls Int'l Airport
Airport Development - Improve existing runway 13/31 pavement and electrical/lighting systems.  The existing pavement and electrical/lighting systems at the airport reached the end of their life expectanicies.  Rehabilitation of the pavement and
Rehabilitate runway 13/31 (Including 4,409 ft X 75 ft whitetopping w/6-inch concrete, connecting taxiway, turnarounds, PAPI's & MIRL's.
Airport Development; Rehabilitate Runway 14R/32L - South (phase 2); Including concrete pavement reconstruction between stations 160+20 to 168+20, underdrains, asphalt shoulders, electrical, and grooving.  Also includes storm sewer, sanitary sew
Rehabilitate Runway [Phase II Runway 14R/32L - South (ARRA)] - 14R/32L
Airport Development.  Design engineering, engineering services during construction, and contractor construction associated with taxiway rehabilitation at the airport.
La Grande/Union County Airport Taxiway A and Taxiway D Rehabilitation
The purpose of this project is airport development, to rehabilitate Taxiway A East at Portland International Airport (PDX) in Portland, Oregon. It includes rehabilitation of approximately 395,000 square feet of the Taxiway A pavement to improve
Taxiway ‘A’ serves as the airport’s primary taxi route to and from the approach ends of Runway 16-34.  Taxiway ‘A’ is utilized by both Army and Air National Guards and general aviation on a regular basis.  Taxiway ‘N’ provides acc
Reconstruct, Mark and Light Taxiway A (North) and Taxiway N
1)Acquire ARFF Vehicle for aircraft and passenger safety and 2)Security Enhancements to provide passenger and employee security
Acquire Aircraft Rescue Fire Fighting Vehicle and Security Enhancements
Airport Development at Martin Municipal Airport in Martin, SD - Rehabilitate Runway - 14/32
This project consists of airfield lighting and pavement rehabilitation for Runway 13L/31R. A major diagonal runway at DFW Airport.  The following work will be accomplished: (1) Installation/replacement of approximately 13,000 feet of duct bank;
Rehabilitate Airfield Lighting & Pavements Runway 13L/31R
Airport Development.  The rehabilitation of the primary air carrier runway
Other Support Activities for Air Transportation
Airport Development -- Reconstruction of Taxiways A, D and F
Rehabilitate and mark Runway 17/35 and reconstruct 17/35 end in Portland Cement Concrete. The improvements will increase and sustain economic activity for the airport and its local community
Rehabilitate and mark Runway 17/35 and reconstruct 17/35 end in Portland Cement Concrete
FINAL -This is an Airport Development project.  The benefit of this project is to rehabilitate the main runway and taxiway at Paine Field.  The asphalt pavement had reached it's maximum design life and was beginning to deteriorate rapidly.  Ini
The award is for an airport development project at the Richland Airport in Richland, Washington.  Runway 8/26 Rehabilitation - The existing 3,995 foot runway was identified in a 2005 Pavement Management Plan to receive a mill and overlay rehabi
Airport Development - This project included the rehabilitation of T/W B and its adjacent apron, as well as constructing holding position markings for Runway 12-30.  This project included rotomilling approximately 20,000SY of pavement, excavatin
373715-Rehabilitate Taxiway  AND 377259-Runway Incursion Markings
Airport Development: Rehabilitate Runway 18/36; Rehabilitate Taxiway
Rehabilitate Runway- 18/36, Rehabilitate Taxiway
Airport Development: Construct Runway Safety Area 01L/19R
VPP - RT 11, ONON CO LN TO VIL OF CENTRAL SQ, OSWEGO CO
Safety & Resurfacing Wheel Road to MD 22
A B WON PAT INTERNATIONAL AIRPORT AUTHORITY
TAFT ROAD, SOUTH BAY ROAD TO NORTHERN BLVD
In an effort to enhance information and communication technologies for our ongoing ICOHRTA research training program, Training for Evidence-Based Health Care Research, Argentina, we will develop and implement a distance-learning course on the c
Training for Evidence-Based Health Care Research, Argentina
Funds are being used to develop and implement new communication and information technologies to track infectious diseases in communities. We are developing 1) an electronic tracking system to collect, process, file, store and retrieve thousands
Subproject for Institution # 08-004034: UC Davis-China Infectious Disease Research Training
This is a revised AITRP proposal for a postgraduate training initiative with an emphasis on HIV/AIDS clinical pharmacology between the University at Buffalo (UB) and the University of Zimbabwe (UZ). The program faculty at both institutions are
ARRA: Antiretroviral Pharacology Training in Resource Poor Countries
With the growing number of emerging infectious diseases and global threats such as HIV/AIDS, tuberculosis, malaria and bio-terrorism, a firm understanding of infectious diseases and microbiology is critical for all healthcare professionals. How
eMicrobes: A Digital Library for Learning Infectious Diseases
This supplement enables a larger sample to be served allowing a more powerful and sophisticated message to be delivered. The additional fudns will be used to hire a new staff member with a masters degree in Social Work. In addition, the request
TELEHERENCE: MONITORING/INCREASING TREATMENT ADHERENCE VIA WEB TELECOMMUNICATIONS
'The RCMI program of Ponce School of Medicine (PSM) is in its 18th year of funding. Currently, the program is funded for a period of 3 years to encourage accelerated implementation of some of the programs that were deemed promising. In order to
ARRA Supplement Rationale.  We are currently initiating the second, and in many ways more challenging phase of this project, i.e. to engage and empower investigators who have little or no experience with approaches and methods of neurogenetics
RCMI MULTIDISCIPLINARY COLLABORATIVE RESEARCH PROGRAM
Projects which expand the District of Columbia health department's capacity to reach more children and adults and increase the number of people vaccinated and thus protected from vaccine preventable diseases.
ARRA- Supplemental Immunization Funding for Reaching More Children and Adults
To enable Section 317 grantees to develop the capacity for billing health insurance plans for services provided to health plan members by state and local health department clinics.  The Immunization Program CHILD Profile will solicit interest f
ARRA - 317 Immunizations & Vaccines for Children - Improve reimbursement in LHJ Health Clinics
GRANT NAME:  ARRA-INCREASE SERVICES TO HEALTH CENTERS. PURPOSE:  To expand the provision of oral health services to uninsured patients by providing accessible and affortable oral health services to adult patients with diabetes, pregnant women a
COMMUNITY HEALTH CENTER OF BURLINGTON, INC.
Project Name: Increased Demand for Services(IDS)The purpose of this funding was to hire medical providers, a eligibility specialist and to purchase IT equipment.  The goals of IDS funding are to increase patients served, increase patients who a
AARA-Increase Services to Health Centers ? The project seeks to expand access to comprehensive health services for growing numbers of underserved and uninsured patients by increasing health center staff by 6.5 FTEs.  The funding will support sa
The American Recovery and Reinvestment Act- Increased Demand for Services funding was awarded to Southwest La Primary Health Care Center, Inc (SWLPHC) with the express purpose of utilizing the necessary staffing to bring quality services to the
The purpose of this award is to address the increased demand for services the FQHCs are experiencing with the current economic decline. The original goals were to 1) retain current staff and 2) recruit additional needed staff. A new position wa
ARRA-Increased Services to Health Centers
Retain medical staff to provide primary health care.
ALBUQUERQUE HEALTH CARE FOR THE HOMELESS, INC.
Increased Demand for Services.  The 195,336.00 award will allow AHCH to create a transdisciplinary outreach team consisting of a part-time Nurse Practitioner, part-time Medical Assistant and part-time behavioral health provider.  This team will
The Award Description is the Increased Demand for Services grant which was a two year grant awarded to Indian Stream Health Center on 3/27/2009 to provide financial support to the health center in order to increase services to the isolated and
ARRA -INCREASE SERVICES TO HEALTH CENTERS. The awarded funds have been, and are currently being used to fund a portion of several employees' wages. The grant funds allowed the clinic to hire several key employees who have been able to increase
ARRA -INCREASE SERVICES TO HEALTH CENTERS
The UnaHealth IDS grant is for the express purpose of hiring a part-time Pediatrician to provide primary pediatric services to the children of the service area. The intent is to provide pediatric access to 609 new patients during the period of
The purpose of this award is to expand access to needed primary care services, support the increase in volume of uninsured patients through patient advocacy and billing support, and increase care coordination due to the increase in demand.  Wit
Increase for Demand Services- Award Number H8BCS11998- The purpose of this award is to expand access to needed oral health care services specifically by expanding health center services to include dental care for the underserved population of V
Dental funding to upgrade equipment and add employees. This is the last quarter for this funding.
Community Health Centers of Greater Dayton (CHCGD) was awarded $101,000 to hire an additional provider, expanding its capacity to provide medical services to an increasing number of people in need, regardless of ability to pay.
The purpose of this award is to expand access by increasing hours at our Lenawee and Monroe health center locations.
ARRA - Increased Demand for Services: This Grant provides funding for the retention of 4.3 Healthcare providers and support staff that were scheduled for a reduction in force action due to lack of funds to support their salaries and benefits. T
(CFHC) service location:  a Family Medicine physician, (1.0 FTE), and medical assistants, (1.5 FTEs), to support the physician.  EXPECTED OUTCOMES: The hiring of a new physician and medical assistants will allow the CFHC to: (1) increase healt
ARRA-INCREASE SERVICES TO HEALTH CENTERS  With the ARRA Increased Services to Health Centers funding PCHS was able to reach our main goal of hiring a full time provider for our Federally Qualified Health Centers.  PCHS had resorted to using a p
ARRA-INCREASE SERVICES FOR HEALTH CENTERS
Camden on Gauley Medical Center, Inc. Increased Demand for Services Grant  COGMC proposes to utilize the $161,095 in the following manner.  COGMC has 2 FTE Physicians and 4.05 FTE Mid-Level Providers located between our Webster County Locations
Name of Project: Increased Demand for Services Purpose of Project:  Expand and/or maintain access to care in Southern Maryland Goals:  1. Maintain primary care services in Nanjemoy MD. 2. Increase access to dental care in urban Prince George's
ARRA - Increased Services to Health Centers: In order to meet the growing demand for services in the area, we will increase our capacity to serve new patients, particularly those who lack insurance. We will do this by adding three new staff pos
Increased Demand for Services - the purpose of this award is to allow Northeast Florida Health Services, Inc. (NEFHS) to retain current health care workers whose positions would otherwise be eliminated due to the current economic conditions.  T
H8BCS12182 ARRA-Increased Services to Health Centers  We intend to implement this IDS project by maintaining (rather than implementing anticipated cuts) the current levels of staffing, saving 2.2 FTE instead of a reduction in force.   Specifica
COMMUNITY HEALTH CENTERS OF PINELLAS, INC.
The purpose of the award to Community Health Centers of Pinellas (CHCP) is to ensure proper staffing to handle the increased demand for services by retaining and adding an advanced registered nurse practitioners (ARNP), an eligibility worker an
This project ARRA - Health Center Integrated Services Development has as its primary goal the hiring of additional employees to support this new FQHC in the the delivery quality health care. The importance of our goal is to contribute to closin
Title:  ARRA-Increase  Clinic Ole is the medical and dental home for Napa County's uninsured and underinsured residents.  We are the only community clinic in the County and the only provider charging for services based on a sliding fee scale.
H8BCS12202:  ARRA - Increase Demand for Services.  The purpose of this funding is to expand services to low income and underinsured individuals in the Minneapolis area.  Specifically, this funding increases services offered in our Dental Depart
ARRA - Increase Services to Health Centers for Dental Care Renew the contract with a dentist for .4 FTE to provide services to uninsured and Medicaid insured clients; hire a .4 FTE dental assistant and a .25 FTE dental receptionist/biller to as
ARRA - Increased demand for services grant. The funds from this grant were used for the salary of a newly hired Pediatrician and Registered Nurse. The hiring of these two positions increased the capacity of the practice and led to new patients,
The purpose of this award is to expand access to needed primary health care services specifically by expanding services at existing health center sites in an underserved area or for an underserved population.
Grant Name: ARRA ? Increase Services to Health Centers Caring Health Center Inc. is an integral part of the community health care system in the greater Springfield with a proven history of addressing issues that affect the health of community r
Increased Demand For Services (IDS) Friend Family Health Center, Inc (FFHC) The purpose of the award is to provide access to critical services in several areas. The areas include: women health services, family case management and health educati
Part time nurse practitioner and part time medical assistant to meet increased demand for services by filling three previously unfilled sessions per week.
ARRA - Increased Demand For Services - Hometown Health Center will increase access for primary care by retaining and creating 9 full-time health care positions (16.5 FTE for the 2-year period) and expanding hours 2.5 hours per week, or by 6.7%,
ARRA - Health Center Integrated Services Development (Increased Demand for Services)
The purpose of this award is to expand access to needed behavioral health care services specifically by expanding services through the Ingham County Health Department's existing Health Care for the Homeless program and its associated community
BEDFORD STUYVESANT FAMILY HEALTH CENTER, INC., THE
BSFHC was awarded increased demand for services (IDS) funds to increase and expand comprehensive primary care services to the medically underserved community of Bedford Stuyvesant in Brooklyn, NY.  These funds are also being used to increase ac
ARRA - Increase Services to Health Centers  The IDS project is designed to maximize dental services, and patient support to/from health care. The Public Health Department has excellent relationships with its 5 partners who will actively partici
Increased Demand for Services Grant awarded to hire more medical provider staff as well as support staff to accommodate the high degree of demand for services in our service area.  It is critical to the population in our service area to receive
Arroyo Vista utilized Increased Demand for Services (IDS) funding to increase immediate access to care within our greater Northeast LA Service Area. We targeted the most vulnerable uninsured populations including the young, chronically ill, wom
ARRA - Increase Services to Health Centers. The grant is to assist FHC to open a new walk-in clinic. The clinic with its expanded hours, open access and expanded support services, is designed to offer seamless health care to the patient populat
CHILDREN'S CLINIC 'SERVING CHILDREN AND THEIR FAMILIES' THE
Increased Demand for Services funding to hire 2.16 personnel to meet the growing demand for sliding fee medical services.
Grant Name- Increased Demand for Services (IDS) - Falls Community Health The purpose of the IDS grant funding is to increase the access mental health and dental services to the uninsured/underserved including but not limited to homeless persons
To expand clinic hours from 36 hours a week to 40 hours a week to serve additional patients. There are 20 employees who will increaseandwill add 1.62FTEs. The clinic will see more patients.
Increased Demand for Services funding was received to fund 1 FTE Pharmacist at the Montezuma Creek CHC Pharmacy, and .53 FTE Registered Nurse at Blanding Family Practice CHC.
Valley Family Health Care's IDS program has three dimensions:  retention of clinical staff, intensification of outreach and case finding efforts, and oral health expansion.  With IDS funding, we were able to retain five staff of the New Plymout
This grant was awarded on 3/25/09 to provide an expanded service to children from birth to 21 years.  The services would be under the umbrella of the Early Periodic Screening, Diagnostic and Testing (EPSDT) program recommended by the State.
Southwest Georgia Health Care, Inc. (SWGHC) was awarded IDS funding to meet the increased demands for services, as well as create 4 new jobs, and retain 1 employee in our underserved and poor communities, which have been hit hard with this econ
ARRA - Increase Demand Services to Health Centers.  Plains Medical Center will retain 4.00 FTE with funds provided by IDS. The goal is to keep the current level of health services to the increasing uninsured population  Staffing: Medical Assist
The name of this grant is Increased Demand for Services. The purpose of this grant funding was to help health centers serve more patients who may be uninsured. The goal of this project included serving more patients who are uninsured, underinsu
1.	Need- PCHS is in need of increased access to health services and continued care for the uninsured population. Additionally, HCH has identified a gap in service for homeless populations and would increase access through additional physician t
ARRA - Increased Demand for Services to Community Health Centers.  Award allowed the organization to hire 2 Full Time employees (1 - Dental Hygienist and 1 - Support Staff) which impoved access to oral health services for the target population.
ARRA - Increase services to Health Centers
FAMILY HEALTH NETWORK OF CENTRAL NEW YORK, INC.
Cortland County, where ten of eleven Family Health Network of Central New York, Inc. (FHN) health centers are located, continues to have a higher unemployment rate than contiguous counties (currently over 10%, up from 7.1% one year ago). In Ca
NORTH SHORE COMMUNITY HEALTH CENTER, INC
Increase Demand for Services. Gloucester Family Health Center Dental satellite of North Shore Community Health, Inc.
BROWNSVILLE COMMUNITY HEALTH CLINIC CORPORATION
The Brownsville Community Health Center (BCHC) has been awarded an Increase Demand for Services grant (IDS) in the amount of $426,613 through the American Recovery and Reinvestment Act (ARRA) in order to increase 4 provider productivity by 10%
Arousal and Attention Regulation in High Risk Children
This project, funded by the U.S. Agency for Healthcare Research and Quality (AHRQ), will improve methods for assessing and synthesizing evidence about the quality and efficacy of health care services.  It will also promote use of these methods
Handling the Receipt of the National Health Service Corps Loan Repayment Program ARRA Applications and Supporting Documents.
The purpose of this contract is to obtain services for the Student/Resident Experiences and Rotations in Community Health (SEARCH) program(s) to provide opportunities for health professions students to serve on multidisciplinary health care tea
This Award is intended to service the Student/Resident Experiences and Rotations in Community Health (SEARCH) program to provide opportunities for health professions students and residents to serve on multidisciplinary health care teams in unde
The UF AHEC Program will develop and implement a Student/Resident Experiences and Rotations in Community Health (SEARCH) program to provide opportunities for health professions students and residents to serve on multidisciplinary health care te
Construct and deliver a modular health clinic to the Ft. McDermitt Paiute-Shoshone reservation in Ft. McDermitt. NV.  Other significant actions include providing new medical and dental equipment.
Project Number: (BE9RL022H6/ BE9RL023H6)- the removal and replacement with more efficient units of 2 low pressure steam boilers in the existing Red Lake Hospital Facility. And the installation of an elevator in the new addition to the Red Lake
Construction of One (1) low steam boiler replacement and installation of a new elevator at the IHS Red Lake
The New Hampshire Immunization Program has awarded six contracts through a competitive bid process to subrecipients in New Hampshire.  These subrecipients are organizing school immunization clinics, providing health education in their communiti
ARRA-317 Immunization and Vaccines For Children Grants
Division of Public Health, 29 Hazen Drive
ARRA-317 Immunization and Vaccines for Children. Utilizing American Recovery and Reinvestment Act (ARRA) funds in Section 317 Immunization Program Supplemental Funding Opportunities provided by the Federal Centers for Disease Control and Preven
Section 317 grantees have been allocated ARRA funding to purchase priority vaccines.  Funding will support operations infrastructure needed to deliver vaccine and account for those vaccinated.  Initiatives to be funded with ARRA grant resources
Purpose: Funds are available from the 2009 American Recovery and Reinvestment Act for Financial Assistance to current Section 317 immunization program grantees. The purpose of this funding opportunity is to enable Section 317 grantees to develo
Improve Immunization Reimbursement in Public Health Department Clinics
The Michigan Care Information Registry (MCIR) is an immunization information system (IIS) developed by the State of Michigan to assist immunization providers in their efforts to increase the immunization levels in Michigan and is currently main
ARRA-317  Immunization and Vaccines for Children Grants, Supplemental Funding for Improving Data Quality and Enhancing Assessment at Immunization Information Systems (IIS) Sentinel Sites
Improve vaccine storage and handling through purchase of thermometers and refrigerators/freezers.  Funding will also be used to upgrade and enhance the State Immunization Information System as well as provide training and help desk support to n
The Colorado Immunization Information System (CIIS) program maintains an immunization information system (IIS) for the State of Colorado to assist immunization providers in their efforts to increase the immunization rates of children and adults
ARRA 317 Immunization and Vaccines for Children Grants
Sphingosine 1-phosphate (S1P) is a bioactive lipid mediator found in high levels in the blood. Signaling by S1P through its G protein-coupled receptor S1P1 is critical for the emigration of T cells from lymphoid organs into circulation. FTY720,
SPHINGOSINE 1-PHOSPHATE SIGNALING IN AUTOIMMUNE REGULATION
The goal of this application is to use the zebrafish to identify novel pathways that regulate stem cell self- renewal in both normal muscle and embryonal rhabdomyosarcoma (ERMS), a pediatric malignancy of muscle. The zebrafish, with its close s
Identification of self-renewal programs in muscle stem cells
Project Summary  A) Scope of the overall project and the anticipated contribution of the requested supplement.  I requested to increase the hours of our current part-time staff to full-time in 2010.  The requested supplement will be used as out
Contral of Breast Cancer by the Endocannabinoid System
Cancer prevention is the most effective strategy to reduce cancer morbidity and mortality. Therefore, it is imperative to develop new investigators in this area of research. Yan Dong, a junior investigator in the field of cancer chemoprevention
Androgen Receptor Signaling in Selenium Chemoprevention
The overall goal of the proposed administrative supplement is to bring advanced technology to  understand the molecular and functional interaction of ANP and NO signaling , to achieve certain new research objectives within approved scope of the
Functional Interaction of ANP and NO Signaling.
The candidate's overall career goal is to establish an independent research program devoted to investigating cellular mechanisms of proteinuric nephropathies, with an emphasis on diabetic nephropathy (DN). Currently, DN is the leading cause of
Endoplasmic Reticulum-Induced Stress and Apoptosis in the Renal Tubule
PTSD and Dual Disorders at the Interface of the MH and CJ Systems ARRA The purpose of this ARRA-funded project is to accelerate the tempo of the NIMH-funded intervention study for PTSD and substance use disorders.  The additional funding allowe
PTSD and Dual Disorders at the Interface of the MH and CJ Systems ARRA
and allowing us to study enrollment into clinical trials when errors of clinical practice are being investigated.
Improving Accuracy & Outcomes of Breast Cancer Screening
My current research agenda falls into two main areas. The first area is my focus on a population-based approach to examining the quality of care for women with breast cancer. The second area is the evaluation of online communication and service
QUALITY OF CANCER CARE EVALUATION AND INTERVENTIONS
The objective of this career development award is to provide Dr. Sharon Giordano with the experience and knowledge necessary to become an independent health services researcher in the field of breast cancer. Dr. Giordano, who is a medical oncol
ADHERENCE AMONG OLDER WOMEN WITH BREAST CANCER
This Research Career Award application is intended to provide research experience and career development opportunities to a new investigator whose career aspiration is to advance the understanding of the epidemiology and prevention of blood-rel
Energy Balance, IGF Dysregulation and Multiple Myeloma
The parent study for this supplement, Oxidative Stress, Antioxidants and Racial Disparities in Prostate Cancer (1K07 CA119109-01A2) is a mentored career development award sponsored by NCI. The main goals of the parent study are to develop the P
OXIDATIVE STRESS, ANTIOXIDANTS AND RACIAL DISPARITIES IN PROSTATE CANCER
The purpose of this K07 application is to build a mentored research and training experience to foster independent professional development in obesity and cancer prevention, specifically focusing on the understudied area of excess weight gain am
College Student Weight Gain: Identifying Opportunities for Cancer Prevention
This pharmaco-epidemiologic study evaluates the chemopreventive potential of statins in malignant glioma and to assess pharmacogenetics as risk-modifiers. The design is a case-control study that recruits malignant glioma cases and matched contr
A pilot study of statin therapy and risk of malignant glioma
The administrative supplement is providing monies to support one part-time (60%) laboratory technician  to perform genotyping, bisulfite modification and sequencing to test the hypotheses outlined in the parent grant K07 CA131094. The laborator
Epigenetics and female reproductive cancers
The purpose of this career development application is to provide a mentored training and research experience to become an independent cancer control investigator with a focus on genomic medicine and cancer risk. Genomic information and personal
The Role of Behavioral Science in Personalized Genetic Medicine
FOXP3 Structure, Function and Regulatory Activity in T cells  --  The transcription factor FOXP3 is required for development of functional CD4+CD25+ regulatory T cells (Treg).  Mutations in FOXP3 lead to a severe systemic autoimmune phenotype i
FOXP3 Structure, Function and Regulatory Activity in T cells
Dr. Yu's long term goal is to understand how the immune system responds to syngeneic cancerous cells and tissues, and how stronger immune responses can be promoted against the malignancies. The current application is intended to uncover the mec
GENERATION AND ANALYSIS OF IMMUNITY INSIDE TUMOR TISSUES
This application is to provide support for a supervised research career development experience for Dr. David Stoltz in the field of airway cell biology. Dr. Stoltz has completed a combined M.D./Ph.D. program and is currently in the Pulmonary/Cr
Paraoxonase-2 S311C Polymorphism Alters Glycosylation and Lactonase Activity
The IGF-I (Insulin-like Growth Factor) receptor (IGF-IR) activates pathways associated with tumorigenesis including hyperproliferation, survival and invasion. Studies outlined in the parent grant aimed to identify and characterize novel genes c
Role of IGF-I Receptor Signaling Pathways in Cell Survival and Migration
Helicobacter pylori is a highly adaptive pathogen that escapes host bacterial defenses (i.e., gastric acid and humoral immunity) leading to chronic infection. The broad, long-term objective of this proposal is to elucidate the factors contribut
Adaptive immune mechanism in acute H. pylori infection
Liver disease is a common cause for morbidity and mortality in the U.S., and understanding the critical pathways during liver development is essential for our knowledge of normal liver function and disease. The zebrafish is an excellent model t
wnt Signaling in Liver Development and Disease
Mutations in rhodopsin are the most common causes of hereditary forms of Retinitis Pigmentosa (RP). Many of these mutations lead to misfolding of rhodopsin protein and retention within the endoplasmic reticulum (ER). The molecular pathways that
ENDOPLASMIC RETICULUM STRESS IN RETINAL DEGENERATION
DESCRIPTION (provided by applicant): Thyroid-related eye disease (TED) is an important public health burden that causes loss of productivity and reduces quality of life. TED can lead to chronic debilitating pain and headaches, double vision, co
A zebrafish model for studying orbital development and disease
The goal of this supplement is to extend findings and hypotheses from the parent grant which proposed that functional variants in drug efflux transporter genes (MRP2, BSEP and BCRP) contribute to wide interpatient variability in chemotherapy di
MRP2, BSEP, and BCRP Transporter Polymorphisms and Chemotherapy Disposition
Sepsis is a disease process characterized by a systemic inflammatory response to an underlying infection. In the United States, 750,000 people develop severe sepsis annually and despite recent advances in critical care, over 210,000 people die
Role of Cyclooxygenase-2-derived prostanoids in polymicrobial sepsis
Described below is an administrative supplemental request for an actively funded K08 grant entitled Non Muscle Myosin II Contractility Putatively Regulates Scar Contracture. This proposal has been devised based on the goals of the NIGMS-Specifi
NON MUSCLE MYOSIN II CONTRACTILITY PUTATIVELY REGULATES SCAR CONTRACTURE
The proposed interdisciplinary study allows the candidateto further develop his knowledge of MR physics and expertise in imaging studies of adrenomyeloneuropathy(AMN), a form of adrenoleukodystrophy(AID), while providing rigorous exposureto the
Imaging the Pathophysiology of AMN in mice and humans
INSTITUTIONAL RESEARCH AND ACADEMIC CAREER DEVELOPMENT  The Fellowships in Research and Science Teaching (FIRST) program is a consortium of two research- intensive institutions, Emory University and the Morehouse School of Medicine (MSM), and t
INSTITUTIONAL RESEARCH AND ACADEMIC CAREER DEVELOPMENT
Specifically, we extended the participation in the PENN-PORT program of Dr. Jennifer Wanat for the grant years 2009-2011. We provided summer employment to MSI partner URM students to enhance their academic and research training as well as the m
Institutional Research and Academic Career Development Award
Overall, this ARRA award will support 1 year of salary for a postdoctoral fellow and a substantial amount of supplies to work on an NIH-funded research project.   The overall objective of the parent NIH grant that encompass this supplement is t
Role of Calcium and Reactive Oxygen Species in Toxicant-induced Immune Failure
Although bipolar disorder (BD) is among the most significant health problems for American adults, causing great morbidity, mortality, and over $40 billion per year in healthcare expenditures, we know far less about BD in children and adolescent
REVERSAL LEARNING IN PEDIATRIC BIPOLAR DISORDER
The candidate is a promising young investigator with board certifications in Internal Medicine and Infectious Disease, and a Masters of Science degree in Clinical Investigation, who has made a substantial commitment to an academic career in pat
, 1K23AR052404. The goals of the parent grant are to study the dendritic cells (DCs) in the skin and blood in normal volunteers and patients with psoriasis during treatment with this anti-CD11a (integrin) biologic therapy. The aims of this supp
Dendritic cells in psoriasis and the effects of efalizumab
Non-Hodgkin's lymphomas (NHLs) are the 5th most common malignancy in the United States, with an incidence that has increased significantly over the last decade. Preliminary data obtained from Adult Lymphoma clinic at DFCI, as well as from Hodgk
Genetic Alterations in Families with Mulitple Lymphomas
The administrative supplement will allow an increase in the recruitment of a general population cohort from 400 participants to 600 participant over the next 2 years. This will translate into a relevant improvement in statistical power for comp
Comparison of kidney function measurement methods in the communithy
Given the plateau in progress made with conventional treatment modalities for many cancers, novel treatment modalities need to be developed. Immunotherapy is an example. Over the past 8 years the Candidate has built an effective infrastructure
Development of Immunotherapeutic Strategies in the Treatment of Lung Cancer
This proposal focuses on understanding the mechanism of GM-CSF-induced sVEGFR-1 production from mononuclear phagocytes and the resulting anti-tumor activity therein. Our data indicates when normal FVB/N female mice are injected with PyMT tumor
(ARRA) The mechanisms of GM-CSF inhibition of breast cancer growth and metastasis
DESCRIPTION (provided by applicant): My long-term career goal is to become a faculty member at an academic center where I will investigate the contribution of microRNAs (miRNAs) to ovarian cancer metastasis. My current career goals are to build
EPIDERMAL GROWTH FACTOR REGULATION OF miR-125a PROMOTES INVASIVE OVARIAN CANCER
The proposed supplement will accelerate research on how single neurons in the frontal cortex and the caudate nucleus reflect visual perceptual decision-making with different reward schedules. This research will identify neural correlates of per
Neuronal basis of reward-biased visual perception
PROJECT SUMMARY (See instructions): The purpose of this supplement request, under NOT-OD-09-060, is to provide meaningful hands-on research experience to undergraduate students interested in pursuing research careers in health-related sciences,
Reactive Oxygen Species: Stress and Damage in Old Muscle
The overarching goal of this Program is to understand the molecular mechanisms that regulate cell activation. Activation of lymphocytes through specific recognition of antigen poses narrowly balanced benefits and risks, and hence is subject to
ANTIGEN RECEPTOR INPUTS: LINKING STRUCTURAL, MOLECULAR, AND CELLULAR RESPONSES
Biological treatment strategies by growth factor and Cytokine inhibitors -Overall goals are to understand the biological mechanisms of Discogenic back pain in patients and test out biological therapeutics in our rabbit disc degeneration model.
The equipment requested will speed up our ability to test eyebrow and tumor tissue for HPV DNA and will insure that tissue cultures needed in project 2 can continue.  The additional personnel will help project 1 meet the enrollment deadlines, r
HPV:  Biology, Clinical significance and Epidemiology
The parent Program “Prospective Studies of Diet and Cancer in Men and Women” (2P01CA055075) supports the continued follow-up of 51,529 men who have completed extensive dietary questionnaires every four years since 1986 (the Health Professio
The purpose of this Program Project Grant (PPG) P01 CA1000730 Supplement Application is to seek support to enhance and expand a currently funded PPG that utilizes integrated retrovirus models to elucidate basic cellular mechanisms that define l
(ARRA) Retrovirus models of lymphocyte transformation and disease
To allow the researcher to pursue independence as they investigate the hypothesis that NK cells respond to autophagic flux of the tumor microenvironment and that differences between tumors in this aspect may determine NK cell tumor homing. In a
Integrating NK and DC into Cancer Therapy
Chronic kidney disease is a major health problem in the United States today, as more than 20 million people (1 in 9 adults) have abnormalities in kidney function, and over 400,000 are on renal replacement therapy. The incidence of this conditio
Cell-Matrix Interactions in the Glomenrulus
The nuclear factor kappa B (NF-kB) family of transcription factors controls inter- and intracellular signaling, cellular stress responses, cell growth, survival, and apoptosis. In resting cells, NF-kB dimers with transcription activation potent
IKB/NF-KB RECOGNITION IN SILICO, IN VITRO AND IN VIVO
Chronic pain is a serious health problem that has remained largely refractory to therapeutic intervention. The development of new pain therapeutics would be aided by a better understanding of the molecular and cellular mechanisms mediating noc
ROLE OF THE MRG FAMILY OF GPCRS IN NOCICEPTION
This supplement supports a Mouse Core (Core B) that is part of the parent Program Project grant.  The supplement is requiested to provide funds for two main purposes:  1) to support the additional per diem charges that will accrue from the exp
MBRS Research Initiative for Scientific Enhancement at North Carolina A&T State NCAT–Summer Opportunity for Academic and Research Enhancement (NCAT-SOARE) Program  The goal of the NCAT-Summer Opportunity for Academic and Research Enhancement
North Carolina Agricultural and Technical State University – Summer Opportunity
The purpose of this supplement is to upgrade the data management and data base components of our Developing Center for Interventions and Service Research in Bipolar Disorders (DCISR) and utilize the data base developed through the several activ
BIPOLAR ILLNESS INTERVENTION IN HISPANIC COMMUNITIES
This funding will directly sopport translational research projects within the Center for Structural and functional Neuroscience (CSFN) that involve the development of technologies and pharmaceutics to address neurodegenerative disorders resulti
Center for Structural and Functional Neuroscience
This project seeks to advance the mission of the COBRE program through funding for recruitment and retention of technical staff.  These positions will support a subset of competitively selected pilot research projects in the Center for Structur
The main purpose of this IDeA Network of Biomedical Research Excellence (INBRE) proposal is to continue to enhance institutional capacity for biomedical and behavioral research in the state of Rhode Island. The University of Rhode Island (URI)
RI Network for Excellence in Biomedical and Behavioral Research
This project seeks to establish the Program in Community Health Research, a research, training, and faculty development program, dedicated to advancing community-based research to improve the health status of low-income communities and their me
OKLAHOMA IDEA NETWORK OF BIOMEDICAL RESEARCH EXCELLENCE
This funding is to support 12 summer undergraduate research fellows from the University of South Dakota, and 6 disadvantaged high school students from South Dakota.  The undergraduates will spend 10 weeks conducting research in a laboratory at
South Dakota Biomedical Research Infrasture Network.
The Kentucky INBRE serves a statewide mission to build infrastructure and capacity for biomedical and health-related research and training as well as for bioinformatics. In this application, the University of Louisville is partnered with the Un
KY IDeA Networks of Biomedical Research Excellence
DESCRIPTION (provided by applicant): This renewal of the COBRE award to the College of Veterinary Medicine (CVM) at Kansas State University (KSU) is requested for the continued support of the 'Center for Epithelial Function in Health and Diseas
EPITHELIAL FUNCTION IN HEALTH AND DISEASE
The LSU School of Dentistry is currently completing the Phase I CoBRE and is poised to pursue phase II in a competitive renewal. The renewal application continues with the theme of ?oral infectious diseases.? Two of the six new specific aims in
MENTORING ORAL HEALTH RESEARCH IN LOUISIANA
The John A. Burns School of Medicine (JABSOM) at the University of Hawaii at Manoa (UH Manoa) is submitting this application in response to National Institutes of Health (NIH) PAR-07-229. With a Center of Biomedical Research Excellence (COBRE)
Institute for Biogenesis Research - BIOMED
scientific infrastructure, resources, and services that can be used in the development and use of rodent models to study pertinent questions on the basic biology of aging. The Center proposed in this application will consist of five Resource C
The USC/Norris Comprehensive Cancer Center at the University of Southern California was founded in 1971 and has been continuously supported by a Cancer Center Core Support Grant since 1973. It has developed into a major regional and national re
USC/NORRIS Comprehensive Cancer Center (CORE) Grant (ARRA ADOPT Administrative Supplement.
USC/NORRIS Comprehensive Cancer Center (CORE) Support-Administrative Supplemental Award for Recruitment of New Faculty
Colorectal cancer is the third most common cancer and the second leading cause of cancer related death in the United States. 75% of patients diagnosed with colorectal cancer will have early stage disease and despite surgical resection for curat
The Roswell Park Cancer Institute (RPCI) has been continuously recognized as a Comprehensive Cancer Center since the NCI designation of such centers in 1974 and is now requesting continued federal support for the next five years. A free-standin
The joint recruitment of a Physician Scientist into the Departments of Medicine and Cancer Biology will complement and synergize with the current faculty and research strengths to broaden the ACC expertise in tumor metabolism or tumor immunolog
ABRAMSON CANCER CENTER OF THE U OF P CORE SUPPORT GRANT
The University of Colorado Cancer Center (UCCC) is the only NCI-designated comprehensive Cancer Center in the Rocky Mountain region - an area with a population of approximately eight million people. The goals are to reduce the cancer burden by:
Optical Instrument and Lens Manufacturing
stories that underscore job and infrastructure related to ARRA research findings.
Provision of Grants Management Support to the OGCM/NINR for ARRA grant projects.  Includes coordination of ARRA funding and reporting requirements, review ARRA grant applications for compliance with NIH and NINR policy and negotiation and prepa
WEB DEVELOPMENT SUPPORT SERVICES ON THE COLLABORATIVE PROJECT BETWEEN OCLA & CBI FOR THE NHLBI ARRA WEBSITE WITH VIDEO BLOGGING
To design and test a method of intervention that has the capacity to promote engagement and adherence to treatment, foster recovery and reduce or prevent disability in patients experiencing a first episode of schizophrenia and related psychotic
Recruit Scientific Reviewers and Prepare Summary Statements for National Institute of Health Grants
Professional services contract to review NIH grant documents.
'Recovery Act' -- Repair & Upgrade Switchgear -- Building 31B
Bus and Handi-Van Acquisition Program, Pearl City Bus Transit Facility Parking Expansion Program, Wahiawa Transit Center, Middle-Street Inter-Modal Center,Bus Stop Pad Improvements Rehabilitation/Renovation, Preliminary Engineering for New Star
P38 MAPK AS A THERAPEUTIC TARGET IN MYELODYSPLASTIC SYNDROME
Individuals of similar body size may differ widely in their risk of cardiovascular disease (CVD), suggesting that factors other than body mass index or total body adiposity are key determinants of adiposity-associated CVD risk.  Deposition of t
ECTOPIC FAT, ADIPOCYTOKINES, AND ATHEROSCLEROSIS IN POSTMENOPAUSAL WOMEN
Partnerships for Adaptation, Implementation, and Dissemination (PAID):  Collaborative Research - Career Advancement for Women through the Earth Science Women's Network (ESWN)
CTSC is responsible for sustaining ETP equipment in the best possible state of readiness for use in protecting the citizens, borders of the United States and ports of entry Outside Continental United States (OCONUS/CONUS).  ARRA funds will be u
The US Customs and Border patrol has a valid requirement for the procurement of large scale non intrusive inspection systems for use on the US borders.  Contract award is now for a total of 35 systems, which included system acceptance and onsit
Search, Detection, Navigation, Guidance, Aeronautical, and Nautical System and Instrument Manufacturing
U.S. Immigration and Customs Enforcement
This award is for 5 Wireless Communications Rapid Response Kits to support a mobile and flexible deployment of communication systems for ICE.
Boiler Controls Installation and Testing, Installation Report, and Crew Training
Construction New Dual Covered Moorings USCG Station Neah Bay, Washington
Award of design build construction of new covered moorings.
In compliance with the transparency and accountability requirement associated with the supplemental appropriations provided by the American Recovery and Reinvestment Act of 2009, the Transportation Security Administration utilized ARRA funds to
Airport Checked Baggage Inspection System - Sacramento Terminal B
LITTLE ROCK MUNICIPAL AIRPORT COMMISSION
Airport Surveillance Program - Little Rock
TSA Advanced Surveillance Program - Closed Circuit Television Camera System
Airport surveillance program Chicago Midway
Airport Surveillance Program - Chicago - Midway
Tree landscaping and miscellaneous work on US 26 at the Dwyer Rest Area in Platte County
Construction perform on Road 16-NE of the Crab Creek Crossing
Federal project I802192, involving concrete rehabilitation and miscellaneous work in I-80, beginning  at reference marker 86.41 and ending at reference marker 101.754, between Green River and Rock  Springs in Sweetwater County.
Federal project I804245, involving grading, milling plant mix, bituminous pavement surfacing, and  miscellaneous work on 6.39 miles of I-80, beginning at reference marker 221.19, between Rawlins  and Walcott Junction in Carbon County.
Federal project I804250, involving removal and replacement of snow fence and miscellaneous work  on I-80 beginning at reference marker 267.19 and ending at reference marker 290.44 between  Laramie and Walcott Junction, for a total of 23.25 mile
2009 American Recovery and Reinvestment Act Capital Fund Recovery Competition (CFRC) Grants funding will be used for energy efficiency activities including replacing refrigerators and lighting with Energy-Star rated appliances.  The 60 scattere
This grant money will be used to build a new community buiding that will include the fire department, first responders, library, city hall, meeting room, emergency disaster shelter, and storage. The current building is outdated and desperately
WYOMING CHILDCARE CENTER. PROVIDE FUNDING TO BUILD A CHILDCARE FACILITY IN WYOMING TO SERVE APPROXIMATELY 52 CHILDREN
Award is to update/improve HUD housing for the elderly/disabled and create jobs that will hopefully help the economy.
Des Moines Housing Authority Public Housing Modernization Program (ACC) - Modernization update for low income public housing facilities.
Energy conservations measures in public housing units, including replacement of stoves, furnaces, water heaters and air conditioners.
Public Housing Capital Funds Energy Conservation Measures
Complet kitchen remodeling for 8 elderly units and 1 family unit. Replace existing rim and interior doors in 28 units.
Construction of New Community Center for the City of Lenox to be used for public uses.
INVEST IN PUBLIC TRANSPORTATION: Purchase one (1) 31 Ft low-floor Medium Duty (MD) expansion bus.  The vehicle will help to expand the spare ratio for the fleet and provide much needed reliable service backup for the aging fleet.  These are fle
Purchase three medium duty replacement buses equipped with security cameras.These  buses will replace buses that have exceeded their recommended useful life and will be used in daily fixed route service.
ARRA grant to purchase three medium duty buses
The grant funds will be used to establish a revolving fund to provide financial assistance to small and emerging private business enterprises in rural areas.  The current award amount was used for establishment of a consignment shop, a  outdoor
Central City Mainstreet Revolving Loan Fund
Community Improvement & Capacity Building
U.S. and Mexico International Boundary and Water Commission
Scope of work included providing personnel and equipment necessary to perform engineering; geotechnical investigations and engineering evaluations (sealed by a licensed engineer), which assess slope stability, levee settlement, bearing capacity
Bidding services and construction management services for the Banker Floodway North Levee Project; units of measure are estimated for 6 months at $29,387.83 per month; for the construction of rehabilitation improvements for 1.6 miles of levee t
Scope of work includes providing personnel and equipment necessary to perform engineering; geotechnical investigations and engineering evaluations (sealed by a licensed engineer), which assess slope stability, levee settlement, bearing capacity
Firm Fixed Price with adjustable amount via 15% difference in quantities - To provide all plant, labor and equipment for the rehabilitation of 2.9 miles of Banker Floodway North Levee, from South Bentsen Road (Sta67 + 00) to Spur 115 (Sta 253-0
538 - (Loan Only) Water Only - 09/10 Stimulus
Overall purpose: procure bus replacements for buses that are well beyond their useful life--urban--and are in this condition because of lack of City resources to replace them.  Expected outcomes:  New bus replacements will reduce the down-time,
. Membrane technology is one of the critical clean technologies for the 21st century. Membrane-based separation and filtration is a significant part of modern industries and intensively applied in water treatment, chemical industry, food indust
This Small Business Research Phase I project contributes solutions to two problems faced by therapeutic techniques using protein drugs:  (i) current carriers for protein drugs are nonuniform on a molecular level and (ii) the efficacy of protein
SBIR Phase I: Well-defined PEGylated multiblock polyamino acids for protein drug delivery
SBIR Phase I: Metal-based microchannel heat exchange systems for electronic devices
This Small Business Innovation Research Phase I project will test 23 food antioxidants (AOs) for their EA or anti- EA.  The project will also examine whether EA levels change after AOs are exposed to common-use-stresses of sterilizing or microw
SBIR Phase I: Food Antioxidants (Aos) With or Without Estrogenic Activity (EA)
This SBIR Phase I project will reduce mechanical external-cavity diode lasers to a centimeter-sized waveguide chip using a novel giant electro-optic effect.  The device, a waveguide external-cavity semiconductor laser (WECSL), will be enviornme
We are investigating a new technology for enhanced night vision devices that can combine shortwave infrared imaging with thermal imaging.
A novel SWIR/MWIR monolithic electro-optical sensor for manportable applications for day/night surveillance
This Small Business Innovation Research Phase I project will address the problem of automating complex multi-step tasks and negotiations for computer users. The focus is on developing representations and algorithms for a personal assistant agen
SBIR Phase I: Crono: Personalized Agents to Save Users' Time
CONCURRENT ELECTRONIC DESIGN AUTOMATION, LLC
This Small Business Innovative Research Phase I proposal will research, develop and demonstrate that the performance of Engineering Simulation and Modeling applications can be dramatically improved using FPGA and GPU accelerated servers. Engine
SBIR Phase I:  Analysis and Acceleration of Engineering Simulation and  Modeling.
SBIR Phase I:  Low-power Real-time Java for Mission-critical Systems  The complete abstract for this award is available in research.gov at: www.research.gov
SBIR Phase I:  Low-power Real-time Java for Mission-critical Systems
This Small Business Innovative Research Phase I research project will demonstrate the feasibility of a high-precision optical metrology system that meets a current market need for extremely precise distance measurements with rapid update rates.
SBIR Phase I:  Fast and Accurate Laser Distance Metrology
This research project is focused on developing microarray bioschips for cell-based and enzymatic reaction screening.  Specific tasks are the following: (1) Optimize the activity and stability of biosynthetically important enzymes and cells enca
Development of Multizyme Chip and Cell Microarrays for Biological Screening
STTR Phase II: Abrasion Resistant Ultrahydrophobic Coatings for Corrosion, Erosion and Wear
Abrasion Resistant Ultrahydrophobic Coatings for Corrosion, Erosion and Wear
This Small Business Technology Transfer Phase I project addresses the need for greater efficiency and clean emissions in power generation systems through the development of nonprecious metal catalysts for oxygen electroreduction based on metal-
STTR Phase I: High-Performance, Non-Precious Metal Oxygen Reduction Catalysts
The aging U.S. population is expected to place unprecedented strains on the country's health care system. To mitigate this, there is growing industry interest towards home-centered approaches to health care. Leveraging technology advances is se
CAREER: Towards Autonomous Wheelchair Systems in Urban Environments
Predicting the behavior of an individual amidst a large number of other people, such as a player in a multiplayer online game or a pedestrian in an urban scene, poses a difficult challenge. This is because an agent's actions are strongly influe
CAREER: Modeling Group Dynamics in Multi-agent Systems
RECOVERY ACT RESEARCH SUPPORT as an NSF CAREER award studying  Authentication and Privacy in Location-based Services such as Google maps
CAREER:  Providing Authentication and Privacy in Location-based Services
The project represents a new paradigm for research in computer vision related to content-based image management--?one that exploits a symbiosis between this technology and the online communities it serves. It is quite clear that communities sta
Replacement of boiler and DHW systems, replace faucet aerators and showerheads, replace remaining incandescent lighting fixtures.
This development is a twenty-story 181-unit Senior high-rise building constructed in 1963 that is in need of boiler and domestic hot water heater replacement.  Project begins in June of 2009 and will be completed by March 2010.  Project work sc
ARRA Capital Fund Public Housing ModernizationProgram Creation of Energy Efficient, Green Communities Fannie Emanuel Apartments
Moderate Rehabilitation - Mary Jane Richardson Apartments
This development is an eight story, 92-unit Senior high-rise building constructed in 1961 that is in need of boiler and domestic hot water heater replacement.  Project work scope replaces equipment that is at or past its useful service life.  P
ARRA Capital Fund Public Housing Modernization Program Creation of Energy Efficient, Green Communities Bousfield Apartments
Energy efficiency improvements at Don Davis Center office and maintenance buildings. Install geothermal heat pump heating and cooling systems, replace lighting with high efficency lighting,and occupancy sensors.
Energy Conservation Improvements at Don Davis Center
Capital construction funds to provide for the rehabilitation and modernization of public housing units.  This grant will fund the ADA upgrades to multiple sites and the rehabilitation of seven (7) sites critical to the Plan for Transformation,
ARRA Capital Fund Public Housing Modernization Program - Formula Grant
HOUSING AUTHORITY OF HENRY COUNTY ILLINOIS
Modernization of 4 public housing developments in Henry County Illinois. Scope of work includes replacing 45 furnices and adding 45 central air conditioning units to 45 family apartments. Maple City Apartments in Geneseo Illinois will have addi
Contract modernization activities at the Braner Building.This funding will be expected to result in providing employment for construction workers and product manufacturers.  In addition, this funding can be expected to substantially modernize p
Capital Funds for improvements to existing Low Income Public Housing
American Recovery & Reinvestment Act Capital Fund Formula Grant
Public Housing Capital Fund Stimulus Grant - The morgan County Housing Authority is implementing the following activities using Capital Fund recovery Act funding: 143 units of the Turner High Rise/Scattered MIDD Sites (IL079000003) public housi
Public Housing Capital Fund Stimulus (Formula)  Recovery Act Fund
HOUSING AUTHORITY OF THE COUNTY OF DEKALB, THE
The ARRA grant will be used to remove all of the original, deteriorating galvanized piping at Golden Years Plaza, a nearly 40 year old, 16-story, 150 unit  hi-rise.  The pipes will be replaced with copper pipes which is expected to improve wate
Conduct modernization activities at various Public Housing Developments, this funding will substantially modernize public housing
Conduct modernization activities at various public housing developments.  This funding can be expected to result in providing cmployment for architects and engineers, construction workers and product manufacturers.  In addition, this funding ca
COMMUNITY FACILITY LOAN-THE PROPOSAL IS THE EXPANSION OF A MENTAL HEALTH CLINIC
The construction of a 200,000 gallon water tower as well as 1,800 linear feet of proposed 8' transmission main from the water tower site to the existing distribution system. The City received approval from USDA about using the remaining availab
Invest in public transportation by purchasing new biodiesel buses.
Purchase 15 biodiesel replacement buses.
PACE, THE SUBURBAN BUS DIVISION OF THE REGIONAL TRANSPORTATION AUTHORITY
Invest in public transportation by purchasing 58 30' transit buses, 190 paratransit vehicles and a minimum of 76 support vehicles for maintenance and supervisory personnel as well as staff at Headquarters. Due to good pricing received on our co
Purchase 62 replacement fixed route 30' buses, Puchase 190 replacement paratransit vehicles, and purchase 83 replacement support vehicles for maintenance and supervisory personnel as well as staff at Headquarters.
Investing in public transportation by purchasing four new 35' buses to replace four 1993 35' buses, by purchasing two new wheelchair lift vans to replace two 1999 wheelchair vans, by repairing and remodeling the bus storage building built in 19
Capital Projects:  Buses, vans and facility improvements.
To fund technical studies to improve existing methods for detecting and controlling lead-based paint and other housing related health and safety hazards, to develop new methods to detect and control these hazards, and to improve our knowledge o
The MIGHTY Study: Moving into Green Healthy Housing
The Hammond Housing Authority will use the CFRC funds for Categority 1 Elderly and/or Persons with Disabilities for the construction of two additions to the existing original structure of 119 units which are solely dedicated to the elderly and/
This project will create new public housing units to replace units that were lost through the disposition and demolition of a former public housing community.  Specifically, PHA will invest in public housing transformation by creating 47 new un
Concrete Repair & Replacement Contract - Force Account Defered Maintenance Program
ARRA Stimulus Grant for the purpose of completing the back-log of capital improvements. The grant will supply jobs as a result of funding to contractors and engineers.
Conduct modernization activities at various Public Housing Developments. This funding can be expected to result in providing employment for architects, and engineers, construction workers and product manufacturers. In addition this funding can
Conduct modernization activities at various locations. The funding can be expected to result in providing employment for architects and engineers, constuction workers, and product manufacturers. In addtion, this funding can be expected to impro
The Town of Macy received sealed bids for the project on August 12, 2010. CSU, Inc of Indianapolis, Indiana was awarded the project.  Presently, the project is under construction and anticipated for completion in spring of 2011.  Original Loan
Installation of sewage collection system and upgrade to wastewater treatment facility. Original Loan Award Amount was $3,163,000.00.  There was a partial de- obligation in the amount of $3,096,000.00 prior to Loan Closing on 08/17/2011  because
COMMUNITY RESOURCE CENTER OF MARSHALL COUNTY, INC.
Community Resource Center that will bring local service agencies to a central location to allow easier access for the community. It will also allow the service agencies to share common space, which will help reduce costs for these programs.
Community Resource Center of Marshall County
USDA direct loan, CFDA 10.780, Community Facilities program.  This project will construct a new addition to the existing hospital consisting of approximately 24,000 square feet on two (2) levels and renovate approximately 9,000 square feet; Cre
Replacement buses and remodeling of the maintenance facility.
Replacement buses and remodeling maintenance facility
Invest in public transportation by purchasing replacement transit buses, rehabilitating a maintenance facility, installing a disaster recovery system, and providing various transit enhancements to system riders.
Replace 6 35' buses, rehabilitate maintenance facility, provide transit enhancements
RECOVERY - ARCHITECT-ENGINEER SERVICES FOR SITE SURVEYS AT OTTAWA NWR FOR THE FOLLOWING PROJECTS: (1) SOUTH BOUNDARY DIKE EROSION REPAIR TAS::14 1613::TAS; FFS PROJECT NO. R3BA (2) DRAINAGE DITCH CLEANOUT TAS::14 1610::TAS; FFS PROJECT NO. R3GF
TAS::16 1410::TAS FFS PROJECT NUMBER R9VA LEED CONSULTING SERVICES AT THE NATIONAL CONSERVATION TRAINING CENTER
Collaborative grant with University of New Hampshire (Cheryl Whistler, PI) as the lead, titled 'Collaborative Research: Use of Genome Enabled Tools to Understand Symbiosis.'  This $76,346 grant to Colorado College Associate Professor of Biology
Collaborative Research: Use of Genome Enabled Toods to Understand Symbiosis
A combined biochemical, molecular and computational approach to understanding the regulation of gibberellin biosynthesis in Arabidopsis.  The gibberellin group of plant hormones regulate many phases of a plant's life cycle from seed germination
A combined biochemical, molecular and computatinal approach to understanding the regulation of gibberellin biosynthesis
The sense of taste is used by all organisms to determine whether potential food items will be ingested or rejected and is critical for the survival of the organism. The taste system is made up of multiple cell types that detect chemicals in foo
ARRA Defining the role of the PLCbeta3 Signaling Pathway in Mouse Taste Cells
The biochemical approach remains problematic given the difficult to sufficiently purify the AGP GalT activity for proteomic analysis. Consequently, we are using 6 putative AGP GalT genes which we identified using a bioinformatic approach. These
Research grant on 'Molecular Control of Ovule Development'.  directed toward the understanding of the underlying genetic and molecular basis of development of ovules, the precursors to seeds.  Primary work is done in the model plant Arabidopsis
Mechanism of Ooctye Renewal in the Adult Zebrafish Ovary  The reproductive capacity of animals is determine, in large part, by the numbers of eggs a female can produce during her lifetime. In mammals, such as humans, new eggs are only produce i
Mechanism of Ooctye Renewal in the Adult Zebrafish Ovary
This award funded services to the Congaree National Park in Hopkins, South Carolina, from the Student Conservation Association's Conservation Intern (CI) program, which recruits and places qualified young people for environmental and conservati
Trails Maintenance Intern - Congaree National Park
trail reconstuction in Sitka National Historical Park
This award funded services to seven National Parks in Alaska, from the Student Conservation Association's Conservation Intern (CI) program, which recruits and places qualified young people for environmental and conservation service projects. SC
Invasive Plant Management in Seven Alaska Parks
Modification 19:  CRA FUNDING TO CORRECT FACILITY DEFICIENCIES AT JACKSONVILLE JOB CORPS ACADEMY: DEF 68779 Dining Hall roof drains, 68785 Recreation foof drains, 68795 Dormitory roof drains & 68798 Dormitory roof drains
This is a supplement to a K23 project entitled ¿Impact of HIV on the T cell repertoire.¿  The parent project  is a cross-sectional study of the effect of HIV infection on T cell diversity. Loss of T cell diversity is thought to play an import
This is a supplement to parent grant K23DK077734 to increase the hours of the research coordinator.  The increased hours allowed the coordinator to extend clinic sessions, enrolled more patients, etc.  All funding was spent as of last quarter.
Gender Differences in Growth in Pediatric Patients with
This project is to enhance research proposed in the original grant by investigating the persistent and on-going injuries in acutely ACL-injured knees using larger cohort of patients and longer follow up after surgeries using MR T1rho mapping te
In Vivo Early Detection of Cartilage Degeneration Using
Rural Business Enterprise Grant to establish a revolving loan fund for small and emerging businesses in the City of Cherryvale, Kansas to utilize in making improvements to their businesses or with help developing their businesses.
Rural Business Enterprise Grant Revolving Loan Fund
Roof replacement at 20 family properties consisting of a significant upgrade using Decra Metal shingles which provided us with a 50 year warranty.
We will characterize the structure and function of Vomp adhesins of the human pathogen Bartonella quintana to better understand how this emerging pathogen causes disease in humans and identify novel strategies to combat B. quintana infection.
Structure and function of Vomp adhesins of the human pat
SABER contract delivery order to renovate the restroom in building 937.
WIDEN STREET TO PROVIDE BIKE LANES AND SIDEWALKS ON BOTH SIDES AND CENTER TURN MEDIAN
BARBER ST: BOONES FERRY RD-BOBERG RD (WILSONVILLE)
Install new waterline to Bldg. 130 for washing town test station for aircraft.
Install new power, fire alarm and HVAC to existing building.
F.E.Warren AFB Aquatic Center Remodel and HVAC Replacement with contract modifications #1 and #2
Remove existing chain link panels and replaced with ribbed metal panels
Remove and replace existing concrete parking lot and asphalt ramp.
Add stimulus funding for identified Lightning Protection Projects and Install HVAC Booster Storage.  Projects include:  Replace comm Warehouse HVAC System; Install HVAC Booster Storage Igloo at Facility 72702; Replace/Upgrade Lightning Protecti
The project replaced critical pump system at a launch facility at Cape Canaveral. The systems douse the area with water to extinguish launch flames.
Install Carbon Monoxide detectors and annunciator to the Fire Station (Building 810), new fire alarm panels in buildings 810 and 250, at Patrick AFB.
Replace the fire alarm panels in building 425, with new Siemens MXLV or equal fire voice activated alarm panels, install new initiating devices in all areas, install manual pull stations at exits.
This is a construction project to furnish and install a pedestrian turnstile.
Mill and resurface existing parking lot at Building 3067, Duke Field, Aux Fld 3, Eglin AFB. Restripe parking spaces as required. Remove Concrete and replace Base course if needed after milling.
at Eglin AFB, FL. Mill existing asphalt, repair base as shown on drawings, repave asphalt, and restripe pavement markings.
Mill and overlay asphalt equipment parking ramp in front of Hanger 1343 - 33rd Fighter Wing at Eglin AFB, FL.
at Eglin AFB, FL. Mill and remove asphalt pavement, remove existing base material, excavate to subgrade, place new base material, install new aspahlt paving, and install new pavement markings.
Replace pavements around Building 690 Parking Lot at Eglin AFB, FL. Mill the existing pavement, compact base as necessary, install new asphalt pavement, and install ne pavement markings.
1.> Archeological Monitoring Services  2.> GEOTECHNICAL BORINGS INCLUDES LAB RESULTS AND REPORT PER BREAKDOWN ON COMP SCH
Energy-Install Capacitor System for Power Factor Conversion
JOHNSON CONTROLS FEDERAL SYSTEMS/ VERSAR JOINT VENTURE
This project will be starated with a Survey phase of the steam traps listed by Wright Patterson Air Force Base for areas A & C. of the base.  This survey will be started and then within weeks a second phase of replacing of the steam traps that
PAINTING IDIQ/REPAIR AND PAINT EXTERIOR B/7423  ESP:HJ - LACKLAND AFB
PAINTING IDIQ/PAINT HUSH HANGAR FLOORS B/1147  ESP:QQ - LACKLAND AFB
PAINTING IDIQ/PAINT EXTERIOR BLDG 934  ESP:BQ - LACKLAND AFB
Repair South Gate, H Street, and J & 5th Streets
Replace Transformer and Switches BLDG 738
Repair Tennessee Avenue and Parking Lot near Building 3448 on Andrews AFB, MD
Repair Roof Bldg 90747. Furnish all labor, tools, equipment, materials, facilities, and transportation necessary to Repair Roof to Building 90747 at Hurlburt Field, FL.
Replace Roof Bldg 91147. Furnish all labor, tools, equipment, materials, facilities, and transportation necessary to Replace Roof Bldg 91147 at Hurlburt Field, FL.
Remove and Replace Roll up Door with Vault Door
Install Auto Fire Protection System LRAFB Building 1024
Rubber Removal/Runway Restripe Spring/Fall 2009
PAINT EXTERIOR O&M FACILITIES PROJECT #FJXT091062A
Installation of 7 foot high chain link fence and terminal posts.  Install 1 foot high 6 strand outrigger on fences and gates.  Remove old chain link fencing and gates.
Install new shower doors,light fixtures, and bathroom accrudiments to two dormitories.
RECOVERY - QJVF 096004 - Repair MAF Utility Closets at Minot AFB, ND
Furnish all plant, labor equipment and materials necessary to accomplish project QJVF 01-0034, Repair Dining Hall HVAC in Bldg 213 Minot AFB ND in accordance with specifications and drawings. The overall purpose of the job is to replace and upd
Replace J-Wing Substation Building 500 at Offutt AFB, NE
Replace Main Feeder Cables at South Vandenberg Power Plant (Building 525)
Project will consist of the complete renovation of one Woman?s Restroom located in Facility 9320, and construction will include demolition of the existing restrooms taking it down to bare existing wood framing walls and ceilings, removing all p
Project consisted of the installation of a new HVAC units serving rooms 200 and 124 at Bldg 8401, VAFB, CA.  Abatement included in proposal as options bid items.  Installation of a redundant A/C unit for Rm 200.  New unit is equal to the existi
Renovation of Horizontal Building, Facility 10719 located at VAFB, CA.  Work included:  Abatement of all materials to the interior structure frame of the building; Installation of new drywall on all walls and prime, texture and paint; Installed
XUMU081459B - Remove and replace 16 chilled water CRAC units at the Western Range Operations Control Center (WROCC), Building 7025, Vandenberg Air Force Base (VAFB), California (CA)
XUMU951041C - Construct storage shed at Fire Station #1, Facility 1740, Vandenberg Air Force Base (VAFB), California (CA).
RECOVERY - XUMU091128B2, Erosion Control, San Antonio Creek
Maintain Interior Base Paint Base Buildings
Furnish and install all labor and material to repair hot water
Docks 3, 5, 7 Low Roofs. To provide labor, equipment and material to replace existing EPDM roofing material with TPO roofing system on Docks 3, 5, 7 Low Roofs at Whiteman AFB.
Demo ceiling tile, ductwork, rooftop HVAC unit.  Install new ductwork, new rooftop unit, control valves in Bldg. 410.
Relocate 21 distance markers, 5 taxi way hold signs, new isolation transformers and mounting pads.  New electrical feeds for runway.
Repair North to Main Backup Feed:  Replace 24 electric poles (45 foot poles) and cross arms (provide vertical construction where practicable) as indicated on the drawings.  Existing poles, cross-arms, and other items not to be re-used shall be
Perform according to scope of work of individual task/delivery orders.
UPCI has been developing a Small Animal Imaging Facility as an additional component of the In Vivo Imaging Shared Facility, a part of the Cancer Center Support Grant (CCSG). This Administrative Supplement entitled Contrast Enhanced Ultrasound I
Establishment of a two year training program in translational cancer research for High School science teachers (grades 9-12) in New Brunswick School District and others across New Jersey and faculty at regional community colleges in New Jersey.
Cancer Center Support Grant - Administrative Supplement Providing Summer Research Experiences for Students and Science Educators
Cancer Center Support Grant (CCSG) Administrative Supplement - Bioinformatics
The Stanford Cancer Center will participate in the planning activities associated with the new initiative entitled ADPOTion of New Technologies for Remote Data Capture and Protocol Authoring (ADOPT),  by providing appropriate clinical and infor
ADOPTion of New Technologies for Remote Data Capture and Protocol Authoring (ADOPT) which is intended to improve the efficiency and effectiveness of the clinical process and reduce clinical trial costs. The Dan L. Duncan Cancer Center (DLDCC) w
Baylor College of Medicine Cancer Center
The Moffitt Cancer Center requests an administrative supplement to its Cancer Center Support Grant (5 P30 CA076292-11) to expand the support for the technological platforms offered by the Microarray Core Facility in the area of the genomic eval
To purchase new equipment to be run by a new ly hired technician and provide pilot funds for novel GI-related projects. This AARA Administrative Supplement requests funding to enhance the ability of the Texas Medical Center Digestive Diseases
Silvio O. Conte Digestive Diseases Research Core Center
This supplement is to accelerate Aim 1C in the original application (1C. We will efficiently curate information derived from the literature and user submission) thereby helping achieve Aim 1 (Increase Database Content), and in a new Aim (Aim 3;
WORMBASE: A CORE DATA RESOURCE FOR C ELEGANS AND OTHER NEMATODES
The purpose of this supplement is to 1) accelerate the tempo of the core research and its clinical translation proposed under the parent grant by recruiting additional research personnel and 2) to translate the technologies developed under core
A Resource for Magnetic Resonance and Optical Imaging
The aim of this supplement is to support  and facilitate a translational application of our ultrahigh magnetic field (7 Tesla) instrumentation and technology. The  specific aim is to directly visualize the deep subcortical nuclei and to use thi
Fourier transform ion cyclotron resonance mass spectrometry (FTMS) developments and applications to the analysis of glycans, peptidoglycans, and proteoglycans are an important component of this research resource. There are two specific aims for
Mass Spectrometry Resource for Biology and Medicine
This grant provided a summer research experience for two students: Tiffany Sanchez, an undergraduate student at Columbia University and Larissa Calancie, a college graduate of May'09 from Cornell University.  The final progress report was previ
Health Effects and Geochemistry of Arsenic and Manganese
The overall goal of this University of Texas M. D. Anderson Cancer Center Genitourinary SPORE in Bladder Cancer is to facilitate innovative translational research in the prevention, detection, and treatment of this disease leading to the elimin
This is a competing renewal application for the Harvard SPORE in Skin Cancer, originally funded in October of 2001. This SPORE is based at Brigham and Women's Hospital and is part of the Skin Cancer Program of the Dana Farber Harvard Cancer Cen
The Oceans and Human Health Center at the University of Miami will enhance and accelerate the ongoing research and training at the OHH Center through research focused on harmful algal blooms (HABs) and their toxins, including evaluating the ext
CENTER FOR TROPICAL AND SUBTROPICAL OCEANS AND HUMAN HEALTH RESEARCH IN MARINE SCIENCE
We describe a mature multi-site IDSC, 'Early Experiences, Stress, and Neurodevelopment' focused on understanding the impacts of early life stress (ELS). We use ELS as a framework to encompass adverse early care conditions: separation/loss, negl
Early Experience, Stress and Neurobehavioral Development Center
Neuroprotection and early detection in PD. This core provides services for our Udall center, including ordering, the management of funds, and assistance with the preparation of manuscripts and progress reports.
Neuroprotection and Early Detection in PD
There is overwhelming evidence for a central role of mitochondrial dysfunction in Parkinson's Disease. This project is based upon our report of a significant association of the mitochondrial J and K haplogroups with Parkinson Disease (PD). In t
At different stages of Parkinson's Disease, the pathological changes occur at different critical brain regions.  Using genomic convergence approach, gene expression from critical brain region will provide valuable candidate genes for further an
The goal of this project is to identify functional variants of environmentally responsive genes that are biologically relevant to motor neuron degeneration of sporadic amyotrophic lateral sclerosis (SALS) and primary lateral sclerosis (PLS).
Rhythmicity and Synchrony in the Basal Ganglia
This NCRR ARRA supplemental award for the Tulane National Primate Research Center (TNPRC) which was funded in late September 2009 provides funding to support and accelerate translational research efforts at the TNPRC.  Funds will be used to hir
The Division of Functional Genomics and Infectious Disease at the Washington National Primate Research Center (WaNPRC) seeks supplemental funding to expand the Center's Pilot Project Program in support of innovative research studies. The WaNPRC
Funds are requested to support a post-doc to begin his faculty career as an Instructor at Harvard Medical School to serve at New England Primate Research Center. These funds will be used to pay salary plus fringe for two years, and for 2 resear
This award enhances the original aims set forth in the NIAMS Multidisciplinary Clinical Research Center proposal entitled, Genetic and Molecular Markers of Methotrexate Efficacy and Toxicity in Early RA (Donna K. Arnett, PhD, Principal Investig
NIAMS MULTIDISCIPLINARY CLINICAL RESEARCH CENTER-ARRA
The purpose of this administrative supplement is to provide funding for summer appointments of undergraduate student researchers to work in laboratories of Washington University Diabetes Research Training Center (DRTC) affiliated investigators.
Diabetes Research and Training Center This application is in response to the National Institutes of Health Notice NOT-OD-09-056 (administrative supplement for Research Center Grants). The Baltimore DRTC requests supplemental funding of programs
Interferon regulatory factor 7 (IRF-7) is implicated in the regulation of Epstein-Barr virus (EBV) latency.  EBV infection is a leading cause of lymphomas especially in immunocompromised individuals and has been associated with nasopharyngeal c
Oncongenic Propertiesof interferon regulatory factor 7
Alcohol consumption during pregnancy is a significant public health problem and may result in a wide range of adverse outcomes for the child. Many of these fetal alcohol exposed children show poor stress tolerance, immune system incompetence, a
Role of Opiates in Alcohol-Induced Neurotoxicity
This is an application for administrative supplement to my currently active RO1 grant 'Short-Chain Dehydrogenases (SDRs) in Retinol/Sterol metabolism'. The overall goal of this project is to understand the mechanisms that regulate the steady-st
The neurosteroid allopregnanolone (ALLO) is a potent positive modulator of GABAA receptors, and evidence suggests that GABAergic neurosteroids are endogenous modulators of GABAA receptors and of selective effects of ethanol (EtOH). The present
NEUROSTEROID MODULATION OF ETHANOL WITHDRAWAL SEVERITY
The Fetal Alcohol Effects and Choline Intervention project examines the potential of choline, an essential nutrient, to reduce the severity of neuropathology and behavioral alterations associated with developmental alcohol exposure.  Using an a
ARRA: Fetal Alcohol Effects and Choline Intervention
Phosphorylation and the CNS Actions of Ethanol  This administrative application is aimed to allow us to purchase a high performing up right microscope that will be used for electrophysiology experiments included in RO1 AA013438 and RO1 AA014366
Phosphorylation and the CNS Actions of Ethanol
from traditional constraints. Preliminary studies suggest that these young women may be unaware of the possible  dangers in this drinking environment. Unfortunately, many discover those risks only when they become  victims of harassment, aggre
Border Girls:  AOD Use, Abuse, and Victimization
In Sioux Falls, two people will be hired to begin working with the Sioux Falls Public Schools to lay the groundwork for eventually in-school screening for developmental disabilities among the general population of first grade children. The hire
FAS Prevention: A Trial of the IOM Model
The Scientific Goal of this application is to accelerate the tempo of the affective regulation component of the parent R01 research (Specific Aim 4) by giving us the capability to rapidly test the mechanism underlying our discovery that high am
ALCOHOL, MEMORY AND AFFECTIVE REGULATION
Chromatin remodeling occurs due to covalent histone modifications. Two major enzymes, histone acetyltransferases (HATs) and histone deacetylases (HDACs), regulate histone acetylation and deacetylation, respectively.  The acetylation of histones
Brain Epigenetic Mechanisms in Alcohol Dependence
gene products similar to those implicated in life span extension downstream of the C. elegans insulin-like signaling pathway. Our preliminary data suggests a model in which mitochondrial MnSOD and retrograde ROS (H2O2) signaling coordinately r
Aging Specific Gene Expression in Drosophila
DESCRIPTION (provided by applicant): This application is for a competing continuation of the currently funded project Internet Interviewing and the HRS. The current project is a joint collaboration between RAND and the University of Michigan. I
Post-menopausal osteoporosis, a global public health problem, has for decades been attributed solely to declining estrogen levels, and although follicle stimulating hormone (FSH) levels rise sharply in parallel, a direct effect of FSH on the sk
ROLE OF FSH IN OSREOCLAST FORMATION AND FUNCTION
This application is for an administrative supplement to Pharmaconeuropathology of Brain Aging and Dementia (R01 AG023810) that exploits the tremendous resources of the Adult Changes in Thought (ACT) study to address the therapeutic imperative f
Pharmaconeuropathology of Brain Aging and Dementia
ARRA - Acute Coronary Syndrome Outcomes for Medicare Patients  The parent grant for this administrative supplement addresses the comparative effectiveness of alternative revascularization strategies for aged Medicare beneficiaries with acute co
ARRA - Acute Coronary Syndrome Outcomes for Medicare Patients
Obesity, insulin resistance, diabetes mellitus, and aging are the leading causes of renal and cardiovascular disease. In addition to the important roles played by hypertension, abnormal carbohydrate metabolism, profibrotic growth factors, proin
Role of FXR in Renal Disease of Metabolic Syndrome and Aging
The goal of the parent grant (AG028657) is to define the pathophysiology of detrusor underactivity (DU), a condition present in two-thirds of frail incontinent elderly. Our studies are designed to implicate MIF (macrophage migration inhibitory
PATHOGENESIS OF DETRUSOR UNDERACTIVITY AND URINARY RETENTION IN THE FRAIL ELDERLY
University of Alabama at Birmingham (UAB) is one of America's premier research universities, ranking among the top 20 in funding from the NIH and earns more than $610 million per year in contract and grant support from federal agencies.  Resear
RUNX2 CONTROLLED ADIPOCYTIC DIFFERENTIATION IN AGING MUSCULOSKELETON
All of the pieces of equipment proposed in our application have been purchased and installed (a Veriti 96 Well Thermal Cycler, Alpha Innotech Gel Imaging System and Accuri C6 Flow Cytometer). A Life Science Research Assistant (the position prop
Regulation of Mast Cell Development and Function
.  E. histolytica faces many complex challenges in the environment of the human host including competition with bacteria in the intestinal lumen and predation by the innate and acquired immune system. It also may be required to sense and respon
Structure and Function of E. histolytica Adherence Lectin
This is an NCRR Competitive Revision Application (NOT-OD-09-058 - 'Enabling RPGs to Leverage NCRR Center and Center-like Programs') submitted as a supplement to R01 AI39480 (Mechanism and function of the regulatory protein LAG-3). The goal of t
MECHANISM AND FUNCTION OF THE REGULATORY PROTEIN LAG-3
This award is issued in response to Notice OD-09-060, Recovery Act Administrative Supplements Providing Summer Research Experiences for Students and Science Educators.  The overall objective of this project is to determine the mechanisms requir
Regulation of B cell Function by Interleukin-12 (Supplement)
Despite being dependent on the same set of cytokines (IL·7 and IL-15) for their survival, memory CD4· T cells generally display a shorter lifespan than memory coa' T cells. We will test the hypothesis that a reduced competitiveness of memory
Malaria continues to expand as a major public health threat throughout the world. The spread of drug resistant malaria and the lack of an effective vaccine make alternative and complementary approaches to malaria control increasingly important.
MOLECULAR TARGETS OF BLOCKING MALARIA TRANSMISSION
AARON DIAMOND AIDS RESEARCH CENTER FOR THE CITY OF NEW YORK, INC, THE
The first specific aim of the R01 grant 'Transmission and Fitness of Drug Resistant HIV-1', AI47033 is to determine the prevalence of transmitted drug resistant variants including those that may be resistant to new antiretroviral targets such a
The Transmission and Fitness of Drug Resistant HIV-1
The ability to invade non-phagocytic host cells is essential for Salmonella virulence. SipA, SipC, SopB, SopE, and SopE2 are five type III effectors that are known to promote Salmonella invasion by modulating host actin dynamics both directly a
Host Actin Cytoskeleton Rearrangements Induced by Salmonella
The award is a supplement to a NIH-supported project. This fund allows us to provide a research opportunity in the biomedical area for a college student or college graduate. The study will generate novel insights on how Ebolavirus replicates. E
Assembly of the Negative Stranded RNA Virus Core
This grant provided a summer research experience for one science educator in health-related scientific research. The summer supplement provided salary and supplies for a high school teacher to conduct research related to the parental NIH grant
These studies will address the role of therapy-induced immune regulation in the immunology of Multiple Sclerosis.  We believe that the results from such an evaluation will provide greater insight into the complex processes that underlie the reg
Role of T Cells in Immune Modulation of Multiple Sclerosis - ARRA Stimulus Compet Rev
Asthma incidence is increasing and warrants investigation of distinct immune mechanisms. Innate, non- antigen-dependent immunity has been shown to play a role in allergic responses. Our data suggest that the innate immune collectin, surfactant
PULMONARY INTERACTIONS WITH INNATE IMMUNITY
Prion diseases are fatal neurodegenerative diseases of humans and animals. Dissemination in the nervous system occurs by prion agent movement along nerve fibers and transynaptic spread between neurons. The long-term goal of the proposed researc
Personnel funds are requested to support an additional half-time compensation for a postdoc (to bring her up to full time support) to process the additional data resulting from our utilization of the electron microscope facility at the Universi
Lipid A (endotoxin) is a glucosamine-based saccharolipid that constitutes the outer monolayer of the outer membrane of Gram-negative bacteria; it is also the active component of lipopolysaccharide that causes life- threatening Gram-negative sep
STRUCTURAL AND BIOCHEMICAL STUDIES OF LPXC INHIBITION
Campylobacter infections constitute the most common bacterial form of gastroenteritis in the US, however, an effective vaccine against campylobacteriosis is not currently available.  In the parent grant, significant progress was made toward th
CAMPYLOBACTER JEJUNI OUTER MEMBRANE PROTEIN VACCINE
This award is issued in response to Notice OD-09-060, Recovery Act Administrative Supplements Providing Summer Research Experiences for Students and Science Educators.  DESCRIPTION (provided by applicant): Complement is the first line of defens
In man, tuberculosis disease is highly associated with increased IL-10 production and the use of murine models has confirmed a critical role for IL-10 in disease progression. In this grant we propose to investigate how IL-10 can influence disea
(ARRA) Immune correlates of reactivation tuberculosis
Calreticulin is an endoplasmic reticulum (ER) chaperone that promotes folding and assembly of glycoproteins, including major histocompatibility complex (MHC) class I molecules. Calreticulin also has the capacity to direct exogenous antigens ont
CALRETICULIN'S FUNCTIONS IN THE ADAPTIVE IMMUNE RESPONSE
The goals of this administrative supplement are (i) to accelerate the  progress of the Parent Grant (AI-068056), (ii) to expand our studies of  influenza to the new pandemic H1N1 strain of flu and (iii) to stimulate  the economy of upstate NY.
GENERATION AND MAINTENANCE OF INFLUENZA-SPECIFIC PLASMA AND MEMORY B CELLS
We received a Summer Student Research Supplement for the Parent grant entitled “Role of insulin-like signaling in the hookworm infective process”. This grant provided a summer research experience(s) for 4 undergraduate students in health-re
Role of insulin-like signaling in the hookworm infective process
The overall purpose of the award is to determine whether pharmacological Inositol (1,4,5)Trisphosphate 3-kinase B (ItpkB)-inhibition could provide an avenue towards cost-effectively reducing detrimental T cell function and cytokine storm in swi
West Nile virus (WNV), a vector-borne pathogen, has resulted in annual outbreaks of viral encephalitis in North America since 1999. Severe neurological disease (encephalitis or death) has been observed in over 30% of the confirmed WNV cases wit
GAMMADELTA T CELL REGULATION OF ADAPTIVE IMMUNIT IN WEST NILE VIRUS INFECTION
Rational and Combinatorial Engineering of AAV Vectors   ARRA PURPOSE OF THE SUPPLEMENT All aims of the parent R01 hinge on molecular cloning. The current supplement request is focused on accelerating research goals outlined specifically in thes
Rational and Combinatorial Engineering of AAV Vectors   ARRA
Chronic bacterial infections cause significant morbidity and mortality worldwide. The World Health Organization estimates that 1.7 million people per year die from Mycobacterium tuberculosis infections, which can lie dormant in a healthy host f
Persistent Systemic Infection of Mice by Salmonella Enterica
The main instrument for our studies at NYU is a Zeiss LSM-710 two photon laser scanning microscope with a Mai Tai HP laser. We have been able to image deep in lymph nodes with this system, but have not been able to reproducibly reach splenic wh
Cellular dynamics in germinal centers during vaccination
HOUSING AUTHORITY CITY OF RUSSELL,  KANSAS
Conduct modernization activities at Public Housing with the addition of 16 steel storm shelters.
ARRA CFRG to prioritize capital projects that are already underway and included in the 5 year plan
Public Housing Capital Fund Stimulas money
Award created a contract for new elderly parking, sidewalk replacement and repair, create new drainage system for sites improvement and improvement of comm bldg/office 504 accessibility widening entries, drainage system improvement and sidewalk
'Distribution Improvements to improve quality of water and reduce losses with loan and grant ARRA Funds totaling  $473,000 and leveraging of $8,000.  544 - (Combo Loan & Grant) Water Only - 09/10 Stimulus'
City of Fall River Water Distribution Improvements
RURAL WATER DISTRICT 4 POTTAWATOMIE COUNTY
This project will install a pre filter system within the District?s water treatment plant in order to remove a large portion of the iron bacteria before the water enters the Reverse Osmosis treatment system.  Install approximately 6 miles of wa
Invest in Public transportation: These funds will be used to purchase replacement public transit vehicles which will invest in transportation, environmental protection, and other infrastructure that will provide long-term economic benefits.
The Owsley County Fiscal Court received a Community Facilities Program grant to partially fund a garbage compactor truck to be used in the county's effort to implement countywide garbage pickup.  The purchase has provided a significant benefit
ARRA Competitive Grant to be used to replace existing resistor type heating units with Energy Star rated PTAC units.
Purchase of three (3) new Dodge Police Cruisers for the City of Monticello,KY Police Department
City of Monticello Police Cruiser CF Grant
Purchase of five  (5) new Ford Police Cruisers for the City of Albany,KY Police Department
The Housing Authority of Providence is implementing the following activities using Capital Fund Recovery Act funding: 60 units of the WESTVIEW APTS (KY085000001) public housing developemnt are being rehabilitated. The purpose and scope of this
Electrical upgrade, HVAC replacement/upgrade in 41 dwelling units.
Upgrade of 139 bathrooms and 69 kitchens in public housing family units.
CITY OF VERSAILLES MUNICIPAL HOUSING COMMISSION
We are installing new furnaces,central air conditioning and new metal frames and doors at entrances to units.
Publis Housing Capital Fund Stimulus (Formula) recovery Act Funded
American Recovery and Reinvestment Act Grant
Improvements to kitchens in one bedroom apartments.
ARRA CAPITAL FUND PROGRAM - REPAIR SIDEWALKS, REMOVE ASBESTOS FROM APTS, EXTERIOR RENOVATION ON TEN STORY APT BUILDING, NEW TV ANTENNAS FOR NEW TV SIGNAL, HVAC FOR APTS, new storefront entries to apt buildings, AND ARCHITECT FEES
ARRA ASSISTANCE TO CAPITAL AND MANAGEMENT ACTIVITIES AT PHA.
PUBLIC HOUSING CAPITAL FUND STIMULUS RECOVERY ACT FUNDED
parking lot renovation, landscaping and community facility upgrades
544 - (Combo Loan & Grant) Water Only - 09/10 Stimulus The Bath County Water District received RUS loan and grant frunds to make system improvements to the water distribution system.
Invest in public transportation by purchasing new hybrid-electric buses, constructing and equipping a new Maintenance and Training facility, re-roofing a bus storage facility, replacing the bus vacuum system and constructing an emergency genera
ARRA Funds for Buses, Facilities and Operating Assistance
OTS is investing in public transportation by purchasing three new transit busses, installing a commercial generator at the Transit Office, and rehabilitating the bus garage by installing a new hydraulic bus lift to assist with maintenance opera
Additional services have been added to do further work with the field offices on refining distance zones for visual resource inventories as per direction from the National Lead.
Jupiter Inlet Restoration, Landscape Architecture.
LOWER HORSEFLY SLASHING TASK ORDER ON CONTRACT #L06PC90336
Recovery Act - Trail Development and Maintenance, San Pedro National Conservation Area Trail Reconstruction and Arizona Strip Trail Repair.  Including the original obligation of $43,200 as well as the $60,000 obligated on July 6, 2010, ACE has
Recovery Act Trail Development and Maintenance, San Pedro National Conservation Area and Arizona Strip Trail Repair
This project was to provide an electrical site design for the Ramsey Mountain Communications site, near Salmon Idaho.  Work performed included sizing conductor, conduit and transformers for a branch line from the power providers transformer to
Soil Preparation, Planting, and Cultivating
RECOVERY- TRICLOPYR 4 AND BARK OIL FOR WEED ELIMINATION
Pesticide and Other Agricultural Chemical Manufacturing
Wheat Field Restoration Project within the Crab Creek Sub-basin.
HOUSING AUTHORITY OF THE CITY OF THIBODAUX INC
Modernizations of Units Remove & Replace Kitchen cabinets & surroundings. Replace top & bottom kitchen cabinets, sink, back splash, stove hood, counter tops, faucets, plumbing & installing GFI recepticles.
Public Housing Capital Funs Stimulas (Formula( Recovery Act
installed a/c and heat in the remaining 8 units on 415 lafleur street
conduct mod activities at various Public Housing Developments
HOUSING AUTHORITY OF THE VILLAGE OF YOUNGSVILLE
Install security fence and security cameras.
HOUSING AUTHORITY OF THE CITY OF LEESVILLE
Conduct modernization activities at the Campbell Loop Development.  Work performed includes correct severe erosion; removing and constructing damaged and broken sidewalks, and removing and replacing sewer trunk lines.  Existing trunk line is so
PUBLIC HEALTH RELEVANCE: The HIV/AIDS pandemic affects over 40 million worldwide and over 1.2 million people in North America. HIV primarily replicates in CD4 helper T cells and can induce adhesive infection-promoting intercellular structures b
MECHANISMS OF HIGHLY EFFICIENT HIV TRANSFER AT VIROLOGICAL SYNAPSES
DESCRIPTION (provided by applicant): Graft-versus-host disease (GVHD) is the major cause of morbidity and mortality after allogeneic hematopoietic cell transplantation. From a genetic perspective, GVHD is a complex phenotypic trait. Susceptibil
CLONING MAJOR GENES FOR LETHAL GVHD IN MICE ARRA SUPPLEMENT
The purpose of this supplement is to increase diversity within the national scientific workforce, and within the scientific population of our institution, by supporting the dissertation research of Mr. Mario Giron, a Hispanic-American student i
Re-specification of the Notch response by the HHV-8 lytic switch protein
The ARRA funds supplement our existing R01 (AI081615, 02/15/09-01/31/14) in two ways. First, funds were made available for the purchase of a unique device that only recently has become available (2009). This one-of-a-kind machine, the Cryomill
We propose to leverage the patient cohort with metal onmetal hip replacements that is available in Specific Aim #2 of the parent grant. These patients have been followed for up to four years with serial determinations of serum metal concentrat
Systemic Implications of Total Joint Replacement
The purpose of this supplement was to provide funds for an undergraduate student to validate a spectroscopic measure of bone acid phosphate composition that could be applied during analyses of bone changes in health and disease.  The student ob
FT-IR Microscopy of Mineral Structure in Osteoporosis
We seek to understand the contribution of extracellular microfibrils to bone physiology and implicitly, to elucidate the pathological underpinning of skeletal manifestations in Marfan syndrome (MFS) and congenital contractural arachnodactyly (C
ARCHITECTURAL MICROFIBRILS IN BONE PHYSIOLOGY
Project Summary/AbstractOsteoarthritis will affect 50 million Americans by 2020. The disease process ischaracterized by the aberrant gene expression and the inability of cartilage chondrocytesto repair the extracellular matrix leading to cartil
Several studies have established that signaling through mTOR is necessary for growth of adult skeletal muscle. The general objective of the parent grant (AR45617) is to define the molecular mechanisms whereby mechanical events and growth factor
Intracellular signaling during skeletal muscle hypertrophy
This is an eight week Minority High School Student Internship with the Department of Biochemistry research faculty working on arthritis research.  This began with the 1) basic quantitative skills, 2) OSHA required training in laboratory safety,
DESCRIPTION (provided by applicant): End-stage organ failure or tissue loss is one of the most devastating and costly problems in medicine. The creation of engineered musculoskeletal tissue with functional myotendinous (MTJ) and neuromuscular (
Engineering Innervated Muscle-Tendon Constructs for Tissue Regeneration
We have initiated the award and  have begun to investigate the role of calcium regulation in hair follicle stem cell biology.  With the ARRA funds we have hired an LRSA I level technician who  started November 30.  No  major equipment  purchase
REGULATING GLI FUNCTION IN HAIR FOLLICLE PROGENITORS
Our overarching goal is to improve patient safety in surgery for spinal stenosis. We hope to achieve this by better informing surgeons' and patients' treatment decisions with individualized data on operative risks. Spinal stenosis is narrowing
Complications of Surgery for Spinal Stenosis: A Clinical Prediction Rule
Meniscal tears are frequent sources of disability, especially in persons with concomitant knee osteoarthritis (OA). Observational studies suggest that while arthroscopic partial meniscectomy (APM) consistently relieves symptoms and improves fun
Partial Meniscectomy vs. Nonoperative Mgmt. in Meniscal Tear with OA: an RCT (Administrative Supplement)
Our preliminary observations, that formed the basis of this application, indicated that the transcription factor FoxO1, through its expression in osteoblasts, inhibits ?-cell proliferation, insulin secretion and insulin sensitivity. The propose
Sirtuin/FOXO Signaling in the Regulation of Bone Mass
Chronic itch or pruritus represents a significant clinical problem for which no effective drugs are available. Molecular and cellular mechanisms of chronic pruritus are not well understood and understudied. Recent identification of the first it
MOLECULAR MECHANISMS OF THE ITCH SENSATION IN THE SPINAL CORD
Keloids are a common form of hypertrophic scar which can be disfiguring.  People who suffer from keloids tend to be African-Americans and South Asians and others with dark skin.  We propose two aims in this project: 1. To determine the number a
Sepsis is a serious problem in surgical and trauma patients and the leading cause of death in critically ill patients. Many septic patients die of organ failure caused by microvascular dysfunction. Our long term goal is to elucidate the mechani
This supplement is made under the Research Supplement to Promote Re-Entry into Biomedical and Behavioral Research Careers program. The project is designed to provide the mentored individual training and a strong background in current molecular
REGULATION OF APOPTOSIS BY PI 3-KINASE/AKT SIGNALING
In this project we seek to pursue as a new and additional specific aim the development of practical synthetic routes to the cortistatin family of alkaloids, broadly defined. Our approach is based on a versatile advanced synthetic template from
Synthesis and Study of Natural and Non-natural Antiproliferative Agents
The parent R01 for this Administrative Supplement is focused on the regulation of the antiapoptotic BCL2 family member MCL1, and the role that MCL1 dysregulation plays in cancer.  These studies utilize MCL1 transgenic mice, which exhibit B and
MODIFICATIONS MATTER IN MCL1 TURNOVER AND CELL VIABILITY
with or without peptides induces lymph-node like aggregates (LNLA) and tertiary lymphoid organs (TLO) in skin,   Aim 2. To determine whether extended immunization (4-6 vaccines) is associated with induction of immune regulatory processes in th
Melanoma vaccines using MHC-associated peptides
Glioblastoma is the most common and most malignant of human brain tumors. Recent therapeutic advances have improved control of primary tumors, with a significant fraction of tumors responding to initial therapies. Unfortunately, all glioblastom
Toward a Molecular Classification of Human Gliomas
Smoking is the primary cause of lung cancer in US adults, and an important cause of mortality from other conditions. Alcohol use is also an important cause of gastrointestinal cancers. Onset of smoking and alcohol use occurs during adolescence
Visual Media Influences on Adolescent Smoking Behavior (Y10-14 Renewal)
DESCRIPTION (provided by applicant): Pancreas cancer kills almost 30,000 Americans each year, due both to local progression and to metastatic disease. We have pioneered the concept of maximizing systemic therapy, while incorporating high dose c
Glucocorticoid hormones are very potent inhibitors of physiological DNA synthesis in keratinocytes in vivo. These hormones are also very effective in preventing carcinogen- and tumor promoter-induced skin hyperplasia, inflamination, and mouse s
GR IMPAIRMENT IN CARCONOGENESIS: TUMOR SUPPRESSOR ROLE
The cell biology pathway of autophagy is emerging as both an important mechanism of tumor suppression and an important mechanism of tumor cell survival.  An important controversy in the cancer field is whether autophagy should be turned on or t
Analysis of Beclin 1 in Autophagy and Tumor Suppression - ARRA Stimulus Admin Suppl
We previously reported a significant association between HHV-8 infection and prostate cancer risk in the Caribbean island of Tobago.  We have also demonstrated HHV-8 protein expression in the non-cancerous prostates of U.S. Caucasian men who ar
Molecular Epidemiology of Prostate Cancer in Tobagonians
The long term goal is to identify molecular mechanisms of cancer initiation and progression and hence to improve cancer prognosis and therapy.   Smads are transcription factors initially identified as signaling molecules for the transforming gr
Role of Smads in the epidermis and skin carcinogenesis
Prostate cancer is the second leading cause of cancer death in man. It is initially responsive to androgen ablative therapy but thereafter patients relapse and develop castration resistant prostate cancer (CRPC). Emerging data suggests that CRP
Human aldo-keto reductases and nuclear receptor action
The purpose of this project is to study Benzene-induced leukemogenesis and its prevention.  These studies are predicated on the following knowledge:  1) benzene-induced acute myelogenous leukemia (AML) displays MLL gene translocations;  2) benz
Mechanisms and Prevention of Etoposide-Induced Leukemia
In the next decade, breast cancer screening will likely be some combination of x-ray, ultrasound (US) and/or optical imaging, if this combination can be performed efficiently. Towards this goal, a proof-of-concept multimodality system is propos
COMBINED DIGITAL X-RAY, OPTICAL, AND ULTRASOUND BREAST IMAGING
Non-Hodgkin lymphoma (NHL) is now the 5th most frequently diagnosed cancer among both men and women in the US. There is rapidly accumulating evidence for several candidate susceptibility genes in the etiology of NHL, supporting a polygenic mode
The MRN-ATM pathway is primarily involved in sensing, signaling, and repairing DNA double-strand breaks (DSBs). DSBs arise as a consequence of external insults, such as ionizing radiation and are generated in all cycling cells during DNA replic
Regulation of the DNA damage response by the MRN-ATM pathway
Upper respiratory tract infection (URTI), influenza like illness (ILI) and acute gastrointestinal infection (AGI) are common in the U.S. and are associated with significant morbidity and economic burden. Accumulating evidence indicates that vit
COLORECTAL CHEMOPREVENTION WITH CALCIUM AND VITAMIN D
The purpose of this Supplement application is to expand the medical record review component of our study of determinants of mortality after invasive breast cancer in middle- and older-aged women. Medical record reviews are a central part of the
There is an urgent need for cost-effective, non-invasive diagnostic techniques for the evaluation of breast lesions. The primary objective of this project is to develop a multiparametric MRI based tissue model to differentiate benign from malig
MULTIPARAMETRIC MRI CHARACTERIZATION OF BREAST TISSUE
The purpose of funding is to test the hypotheses that MIF is critically important for oncogene-induced cyclin D1 expression, Rb  inactivation, malignant transformation and de novo tumorigenesis and that MIF participates in cyclin D1 overexpress
Role of MIF in Rb inactivation and Tumorigenesis
It has recently been appreciated that the aggressive behavior of malignant tumors is related to their extracellular environment.  Laminins are the major extra-cellular components of basement membrane that cover the basal surfaces of epithelia a
LAMININ-8 AND LAMININ-10 IN SQUAMOUS CELL CARCINOMAS
The long-term objectives of this proposal is to understand the molecular mechanisms of prostate tumorigenesis due to deregulation of the P13K and PTEN pathway, and to elucidate the connection of P13K and PTEN downstream signaling components to
P13K Pathway in Prostate Tumorigenesis and Angiogenesis
We have advanced the development of an imaging method for CRAds based upon capsid incorporation of imaging motifs.  This capacity allowed assessments of CRAd parameters in vivo related to viral persistence. On the basis of these findings, we so
CAPSID-LABELED ADENOVIRUS FOR VIROTHERAPY MONITORING
The cellular immune system holds much potential for mediating antitumor responses in cancer patients. Melanoma is particularly appealing to study immunotherapy, since several melanoma-specific antigens recognized by T cells have been identified
DC VACCINATION TO ENHANCE ADOPTIVE T CELL TRANSFER
Melanoma RAS/BRAF Mutation:  Heterogeneity-Risk-Prognosis (R01CA112243; PI: Thomas) Administrative Supplement.  This study is an international population-based, case-only melanoma study nested in the Genes, Environment and Melanoma (GEM) study
Mutations in the NF2 tumor suppressor gene underlie Neurofibromatosis type 2 (NF2), a familial cancer syndrome featuring the development of central nervous system tumors. The NF2-encoded protein, Merlin, is closely related to the ERM (Ezrin, Ra
Molecular Function of the Nf2 Tumor Suppressor, Merlin
This adminstrative supplement is for resequencing and additional genotyping.  The supplement will enable the retention of laboratory personnel and enable accelerated progress of the grant, as well as provide preliminary data for other grant fun
Inherited genetic variation and predisposition to testicular germ cell tumor
Occupational exposure to arylamines used in the manufacturing of industrial dyes was the first known cause of human bladder cancer. These carcinogenic arylamines, specifically, 4-aminobiphenyl (4-ABP), beta-naphthylamine, and benzidine, are als
Genetic and Environmental Risk Factors for Bladder Cancer
We have demonstrated that epinephrine at concentrations observed during stress induces PKA-dependent phosphorylation of the pro-apoptotic protein BAD and protects prostate cancer cells from apoptosis (JBC2007 in 'appendix'). Furthermore, recent
Stress-activated signaling in prostate cancer
The overall purpose of this award was to upgrade the current Quantitative Genetic Epidemiology high performance computing (HPC) cluster.  The expected outcome was that we would purchase the necessary equipment to upgrade the HPC cluster, and as
Methods for Assessing Genetic Association with Time-varying Phenotype
individuals, and more potent therapeutic benefits for patients with advanced disease. The long-term goal of this proposal remains improvement in patient outcome for a malignancy with near-uniform lethality.
ARRA: Multifunctional Nanoparticles in Diagnosis and Therapy of Pancreatic Cancer
This administrative supplement to NCI grant R01CA120185 provided funds to purchase an Applied Biosystems (ABI) 7900HT real-time PCR machine which allows direct measurements of gene expression in cells and tissues.
C-MYC-REGULATED MICRORNAS IN NORMAL AND PATHOLOGIC CELLULAR PHYSIOLOGY
This research grant will attempt to identify all the serum glycoproteins that have increased levels of fucosylation in the sera of patients with hepatocellular carcinoma (HCC). It is acknowledged in the literature that changes in glycosylation
Identification of Altered Glycan and Glycoproteins in Viral Induced Liver Cancer
The specific aims of this project are: 1) to identify new natural product inhibitors of Hsp90, libraries of natural products and their derivatives will be screened for their ability to inhibit the Hsp90- dependent refolding of luciferase and Hs
Identification of Natural Product Inhibitors of HSP90 as Chemotherapeutic Agents
The purpose of this award is to provide a student with post-master's training. The minority fellowship plan will provide her with a 2-year translational research experience within the aims and scope of the parent R01 project.
Mindfulness Based Stress Reduction for Psycho-Immune Dysregulation in Cancer
The overall goal of this research project is to improve the accuracy and reliability of cone-beam computed tomography (CBCT) guidance of radiation treatment in lung and liver. The treatment of inoperable tumors in lung and liver remains a thera
RESPIRATORY MOTION-REDUCED CONE-BEAM CT GUIDANCE OF RADIOTHERAPY IN LUNG & LIVER
Quitting smoking adds an average of seven years to a parent's life, improves the health of the spouse, eliminates the majority of secondhand smoke (SHS) exposure of the children, reduces tobacco-related poor pregnancy outcomes, eliminates the g
Addressing Parental Smoking by Changing Pediatric Office Systems
15-PGDH is a prostaglandin degrading enzyme that my laboratory, in a recent 'from the cover' PNAS paper, has shown is a new candidate colon cancer suppressor gene that acts as an enzymatic antagonist of the COX-2 prostaglandin synthesizing colo
15-PGDH, A Novel in Vivo Suppressor of Colon Neoplasia in Mouse and Man
The long term objective of this proposal is to gain insight into the mechanisms involved in Toll-like receptor (TLR) enhancement of anti-tumor immune therapy and to translate these findings towards practical immunotherapies for patients with me
Increased mammographic breast density is one of the strongest risk factors for breast cancer, is common in the population, and may account for a large proportion of cases of breast cancer. This supplement enhances the overall goal of R01 CA1289
Identifying Genes for Mammographic Breast Density
Lung cancer is the leading cause of cancer-related deaths, with the majority of deaths due to failed therapy from tumor drug resistance. As described in the original application, we have developed a microarray screen for identifying differentia
microRNA regulation of drug sensitivity in non-small cell lung cancer - ARRA Stimulus Admin Suppl
The purpose of this administrative supplement is to conduct a pilot study to assess Vietnamese American social networks and their roles in CRC screening to accelerate the tempo of scientific research.  The specific aims are: 1) To qualitatively
Roles of Social Networks in Lay Health Worker Interventions and Colorectal Cancer Screening
agents. The specific cellular targets of anti-stromal therapy can be visualized in these color-coded models. In this administrative supplement, we propose to purchase equipment <$100,000 that will enable us to complete the proposed research in
COLOR-CODED IMAGING OF PANCREATIC CANCER MICROENVIRONMENT FOR DRUG DISCOVERY
Cancer is one of the leading causes of death in the US. Chemotherapy remains an important cancer treatment modality. Traditionally, cytotoxic molecules that activate only a single tumor-killing mechanism are used. Combination chemotherapy is no
Combination therapy using tumor-targeting synthetic dsRNA and gemcitabine
The purpose of the supplement is to increase the scope of work that will be accomplished to test the hypothesis of the parent project.  One of the aims of the parent project is to determine the mechanisms that regulate the release of the endoca
Biochemistry of Anandamide, An Endogenous Cannabinoid
).  This project seeks to use combinations of clinically-available drugs to reverse behavioral and neurobiological alterations in animals models of cocaine abuse.  To date, we have demonstrated that combinations of a dopamine (DA) agonist and a
COCAINE WITHDRAWAL: A WINDOW OF TREATMENT OPPORTUNITY
In our original proposal we sought to demonstrate the expression of chemokine receptors by neural progenitor cells in the adult brain, to examine the effect of SDF1/CXCR4 signaling on adult neural progenitor cells in the dentate gyrus (DG), and
Chemokine Receptor Function in the Nervous System
Dual-diagnosis in psychiatry refers to the co-existence of drug abuse with a psychiatric condition. This is quite prevalent in schizophrenia, where more than 50% of the patients abuse some type of drug. There is no agreement in the field regard
DISCOVERY OF SMALL-MOLECULE ORPHANIN FQ RECEPTOR LIGANDS  The nociceptin receptor (NOP, previously known as the opioid receptor-like receptor ORL1) and its endogenous ligand nociceptin or orphanin FQ (N/OFQ) have been shown to play a role in th
DISCOVERY OF SMALL-MOLECULE ORPHANIN FQ RECEPTOR LIGANDS
Heroin abuse increases the risk of HIV infection and may exacerbate HIV encephalitis (HIVE). Since a large percentage of newly infected HIV patients abuse opiates, this enhancement of disease process has serious medical and social consequences.
Glial Progenitors as Targets of HIV/Opiate Interactions
Long projection axons regenerate poorly through the damaged central nervous system. One key reason is the environment through which they must re grow contains many biochemical signals that trigger signaling pathways which inhibit axon outgrowth
This grant provides support to use phage evolution of a bacteriophage peptide expression library to identify peptides that can a) bind to the tympanic membrane; b) be internalized by tympanic membrane cells and 3) transit from within the tympan
Our studies have revealed that the spiral ganglion is more than just a collection of axon-like elements that act merely as a simple relay into the central nervous system. Instead, we and others have found that this relatively homogeneous group
Ion Channel Diversity in Primary-Auditory Neurons
DESCRIPTION (provided by applicant): The sensation of smell enables us to gain valuable information about a plethora of chemicals in our immediate environment, and to respond appropriately. Olfactory receptor neurons (ORNs) are responsible for
Studies conducted under this grant are directed at understanding the second messenger-gated ion channels that mediate the transduction of bitter, sweet and umami taste. These tastes are detected by G-protein-coupled taste receptors that initiat
Somatosensory Basis of Speech Learning and Control
The long-term goal of my laboratory is to elucidate the mechanisms that control mechanotransduction in hair cells, and the defects in this process that cause deafness. We propose here to use electrophysiological recordings to determine the exte
Mechanosensor Development, Function, and Dysfunction
The aim of the proposed research is to assess the sensitivity of the latency of the P1 cortical auditory evoked potential as a marker of the development of the central auditory pathways in hearing impaired children who receive intervention thro
Central Auditory Development in Hearing Impaired Infants
2009Capital Fund Recovery Grant (CFRG)Modernization and replacing of waters gutters, refrigerators,painting, showers and redo parking area.
THIS WILL BE USED TO REPAIR THE CHALMETTE FERRY LANDING WHICH IS IN IMMINENT DANGER OF COLLAPSE.  THIS FERRY IS USED BY APPROX 500,000 VEHICLES EACH YEAR TO CROSS THE MISSISSIPPI RIVER FROM ORLEANS PARISH INTO ST BERNARD PARISH.  WITHOUT THIS C
Invest in public transportation by completing funding of the final phase of the multimodal center, complete funding for one additional bus, fund bus shelters, fund safety and security equipment, fund new bus stop signs, fund bus stop ADA improv
Invest in public transportation by purchase of new compressed natural gas (CNG) buses; construction of a CNG fuel station; conversion of the existing maintenance facility to CNG fueling; rehabilitate/upgrade a 22 year old bus terminal; acquire
Purchase buses, renovate facility, preventive maintenance, purchase miscellaneous equipment.
River Parishes Transit Authority will invest in public transportation by  performing preventative maintenance and operations on existing buses.
Purchase of new vehicle and provide preventative maintenance on existing buses.
Washington Fields Rd; Indian Springs Dr to Telegraph
Working with youth to provide safe work and educate them in abondoned fence removal
Recreational opportunities and transportation management (associated with recreational activities) on BLM lands within Trinity County.
'Highway Infrastructure Investment Grant: Urbanized Areas over 200K Population, Rural Areas with Population under 5K'
Litchfield Park - Various Locations Citywide - Functionally Classified Roadways
I-575 FROM I-75/COBB TO ETOWAH RIVER/CHEROKEE
SR 137 FROM CS 505/NORTH MCDUFFIE STREET TO TAYLOR COUNTY LINE
SR 7 FROM SR 96/PEACH TO SR 22/US 80/CRAWFORD
SR 360 FROM PAULDING COUNTY LINE TO SR 176
SR 11BU FROM SR 11 CONN/US 341 TO SR 11 CONN/US 341 IN PERRY
The Tax Credit Assistance Program (TCAP) will fill financing gaps caused by the reduction in equity investment in the Low Income Housing Tax Credit (LIHTC) program.  TCAP will provide gap financing for the construction of affordable housing pro
CALIFORNIA TAX CREDIT ALLOCATION COMMITTEE
The U.S. Department of Housing & Urban Development (HUD) provided grant funding to the California Tax Credit Allocation Committee for capital investment in qualified Low Income Housing Tax Credit (LIHTC) projects. The Tax Credit Assistance Prog
Tax Credit Assistance Program (TCAP). This program provides additional funding for capital investment in low-income housing tax credit projects.
The Tax Credit Assistance Program (TCAP) fills financing gaps caused by the reduction of equity investment in the Low Income Housing Tax Credit (LIHTC) program.  TCAP provides gap financing for the construction or rehabilitation of affordable h
Tax Credit Assistance Program provides funding assistance for affordable rental housing projects that have been allocated Low-Income Housing Tax Credit and need additional equity. TCAP financing is a gap-financing tool for the construction or r
The Recovery Act appropriated $2.250 billion for the Tax Credit Assistance Program, a grant program to provide funds for capital investments in stalled Low Income Housing Tax Credit projects. The expected benefits of TCAP are to increase longev
The Tax Credit Assistance Program (TCAP) will fill financing gaps caused by the reduction of equity investment in the Low Income Housing Tax Credit (LIHTC) program.  TCAP will provide gap financing for the construction or rehabilitation of affo
HOUSING FINANCE COMMISSION, WASHINGTON STATE
The Tax Credit Assistance Program was created to facilitate the development of projects that received or will receive Low-Income Housing Tax Credits awards between October 1, 2006 and September 30, 2009.  Another major purpose is to create new
Reimbursement of the federal share of remedial action costs as authorized by Title X of the Energy Policy Act of 1992. Reimbursements are for work performed approximately 2 years or more prior to the reimbursement.
Reimbursement of the federal share of remediation and oversight costs associated with the American Nuclear Coporation site in Fremont County, Wyoming under Title X of the Energy Policy Act of 1992.  The work was performed approximately 2 years
Grand Lake Welcome Center Site Imprvmnts
Purchase of hydraulic dollies and a 90-ton crane
G & H BARGE REPAIR AND FABRICATION, L.L.C.
KeKaulana Dry Dock Overhaul including: a.  Ballast Tank #1 to #8 rebuild/renewal b.  Apron replacement
PURCHSE OF TWO (2) TEREX CRANES, CRITICAL SHIPYARD COMPONENTS (WELDING EQUIPMENT) AND DRYDOCK MODIFICATIONS.
REPLACEMENT OF CRANES, CRITICAL SHIPYARD COMPONENTS AND DRYDOCK MODIFICATIONS
PURCHASE OF PLASMA TABLE, WELDING POWER SOURCES AND WIRE FEEDERS, 1500 TON PRESS BRAKE AND ANGLE BENDING ROLL
Grant funds under the American Recovery and Reinvestment Act, 2009, Public Law 111-5, February 17, 2009 provide that the Maritime Administration shall establish an assistance program for small shipyards to be used for capital improvements, and
The grant will be used to purchase equipment to transport product within SBI facilities, from raw material to the finished product.  Equipment will also be purchased to assist in the manufacturing process, allowing SBI to work with larger raw m
SAFE Boats International - Small Shipyard Grant
The Boston Housing Authority (“BHA”) seeks $4,062,717 in CFRC Category #1, Activity #4 funding to create a comprehensive services center for frail elders at its Amory Street Elderly/Disabled development.  These CFRC funds coupled with $203,
Public Housing Capital Fund Recovery Competitive Grant
Conduct modernization activities at various Public Housing developments.  This funding will provide for the replacement of worn siding with new vinyl siding on 23 buiildings; the replacement of 2 roofs on high rise buildings; the replacement of
Grant funds will be used for public housing modernization and redevelopment.  At the Washington Beech site, the construction of 37 units of new public housing will be funded by the ARRA grant as part of a larger HOPE VI mixed-finance redevelopm
Public Housing capital Fund Recovery Grant, Public Housing Modernization
The award consists of funding for the following: 1.  Roof replacement of the buildings at a family complex and at 2 elderly/disabled developments. 2.  Comprehensive kitchen and unit modernization at one family development and one elderly/disabl
Modernization at all public housing developments, to replace siding, front doors and side ligts that are energy efficient.
HUD Capital Fund Recovery Grant - Formula based
This grant will allow MART to invest in public transportation by allowing us to purchase new vehicles and equipment and to construct a vehicle storage facility to protect our investment. An original budget of $750,000 is allocated to the purcha
GREATER ATTLEBORO-TAUNTON REGIONAL TRANSIT AUTHORITY
Invest in public transportation by purchasing low-floor buses, minibuses and vans; purchase scheduling software; construction of renovations to commuter rail station; construction of improvements to bus facility; construction of accessible walk
Purchase bus, minibus, vans; construct improvements at train station, bus terminal, walkway, prev. maint., scheduling software, ADA service; SmartCard & software
MERRIMACK VALLEY REGIONAL TRANSIT AUTHORITY
Invest in public transportation through the renovation to the MVRTA's only office/maintenace facility which will result in replacement of existing heating and electric systems with more energy efficient systems and the installation of solar pow
Construction of Office/Maintenance Facility Renovations n Haverhill and Transportation Center in Amesbury
The late endosome and vacuole of yeast Saccharomyces cerevisiae are functionally equivalent to the mammalian late endosome and lysosome. Yeast offers the advantage of both conventional and molecular genetic tools and large majority of yeast gen
RUI: Characterization of a Yeast Gene (ENV7) Involved in Vacuole Structure and Function
Department of Biological Sciences, CSULB
Title: NSF CAREER: Understanding Molecular Networks Controlling Plant Glucosinolate Metabolism. Plants produce thousands of chemicals that are important to their growth, development and interaction with the environment. Many of these chemicals,
Career: Uncerstanding molecular networks controlling plant glucosinolate metabolism
CALIFORNIA STATE UNIVERSITY, CHANNEL ISLANDS
This study will use a copper-binding protein to examine how partner atoms and molecules participate in protein folding and stability. Many of these experiments, and the activities that support them, will be woven directly into the curriculum of
Binding and biomolecular dynamics in undergraduate teaching and research
Intellectual Merit All animals rely on their ability to sense and respond to their constantly changing environments to survive. Because they do not have eyes or ears, C. elegans (small roundworms) depend heavily upon their ability to taste and
ARRA: Analysis of the Regulation of G Protein Coupled Sensory Signaling in C. Elegans
Structural studies of proteins associated with the antiviral response in Archaea.
Structural Studies of Crenarachael Viruses
shifts in gene expression drive differentiation of tissues and the evolution of new morphologies in multicellular organisms. However, studies linking the evolution of gene expression and the evolution of development are difficult in complex org
Collaborative Research: The evolution of gene expresson underlying fruiting body development in fungi
HOUSING OPPORTUNITIES COMMISSION OF MONTGOMERY COUNTY MARYLAND
Conduct modernization activities at Elizabeth House, public housing for the elderly and handicapped.  This funding can be expected to result in providing employment for architects and engineers, construction workers and product manufacturers. I
to improve its structural integrity and curb appeal.  Over 60 units are targeted to be rehabilitated mostly with force account labor.  However, 30 of these units are to be competed by Request for Proposals (RFP).  An architectural firm has bee
Conduct modernization activities as various Public Housing Communities.  This funding can be expected to result in providing employment for architects and engineers, construction workers and product manufacturers. In addition this funding can b
The funds in this grant are awarded to Locally Operated Transit Systems to invest in public transportation. Projects included are the purchase of rolling stock including replacement and expansion buses and bus rehabilitation, bus station, bus s
Buses, Facility Rehabilitation and Equipment
545- (Combo Loan & Grant) Waste Disposal Only - 09/10 Stimulus
Upgrade the Town of Farmington's Tannery Brook sewer main to eliminate raw sewage overflows/breaks, and to reduce infiltration and inflow.
Town of Farmington - Tannery Brook Area Project 2009
Roof Replacement and Bathroom Renovation
544-(COMBO lOAN & GRANT) WATER ONLY-09/10 STIMULUS
545 -Wastewater Infrastructure Project - Lagoon Upgrade; Surface aeration being changed to diffused air in Lagoon #1
Northern Maine General (NMG will build a 7300 square feet single story office building on a site currently occupied by its business office.  The new structure will replace a two story building approximately 3500 square feet build in the early 1
Early Cortical Processing in Schizophrenia
Effectiveness of Suicide Hotline Training
Cortical Interneuron Number and Expression Profile in Schizophrenia
Social Experience and Remodeling of Amygdalar Circuits in Rat Adolescence
New construction of residential group home and school
Adult Daycare / Congregate Meal Service Building
Replace old watermains to improve reliability of water delivery system.  Replace deteriorated water storage tank with new tank.
Equipment and Furniture for New Police/Fire Hall
Purchase of Street Sweeper and Mower for use in the City
Public Housing Capital Fund Competitive (Recovery Act Funded) grant being used to install energy efficient windows, new roof and a green roof on lower roof of public housing elderly high rise building. New domestic hot water tanks also being in
Flint Housing Commission Competitive Grant for Centerview Apts.
Conduct modernization activities at various Public Housing developments. This funding can be expected to result in providing employment for architects and engineers,construction trades and product manufacturers. This funding can be expected to
Modernization and energy efficiency mechanical improvements at 193 scattered site family dwellings and three public housing senior/disabled high rise developments.
Conduct modernization activity at one public housing development. Tear off and roof replacement on apt. buildings in elderly complex.
ARRA Capital Fund Program-roof replacement
Rebuild two (2) exterior decks and construct a 1,155 sq. ft. addition to the Vicksburg Halls facility - HUD Project No. MICH 161-1.  The addition provides space for a Beauty Salon/Barber Shop, Exercise Room and Lounge.
Conduct modernization activities, specifically 504 rehab to 6 apartments and new roofs
Conduct modernization activities as various Public Housing Communities.  This funding can be expected to result in providing employment for architects, engineers, construction workers, and product manufacturers.  In addition this funding can be
Modernization of unit lighting in elderly/ handicapped building. Replacement of roof-top air exchange system.
Invest in public transportation by upgrading a heat, ventilation. & air conditioning (HVAC) system and lighting system in our maintenance and control facility (MCF) that is twenty-four year old.
HVAC upgrade at Maintenance and Control Facility
544 - (Combo Loan & Grant) Water Only - 09/10 Stimulus.  Creation of new drinking water treatment facility.
Edenville Township Water Distribution Project
544- (Combo Loan & Grant) Water Only - 09/10 Stimulus.  Upgrade and replace water mains throughout the village.
544 - (Combo Loan & Grant) Water Only - 09/10 Stimulus. Approximately 5,000 feet of new water main, hydrants, valves, services will be installed in heart of water system.
539 - (Loan Only) Waste Disposal Only - 09/10 Stimulus. Constructing a new wastewater pump station and related improvements along with the demolition of abandoned treatment facility building(s), tanks and other sturctures on our site. The const
Loan to purchase a new pumper for the City's Public Safety Department - replacing a 1990 model.
Purchase a plow truck for street maintenance and public safety
Public Facility and infrastructure improvements. Construction of new downtown parking lot.
MANKATO HOUSING & ECONOMIC DEVELOPMENT AUTHORITY
Competitive Public Housing Capital Funds
HOUSING AND REDEVELOPMENT AUTHORITY OF WINONA, MINNESOTA
Public Housing Capital Fund ARRA-conduct modernization activities in 16 units of multi-family public housing; conduct modernization activities in 130 unit public housing hi-rise (replace doors and locks)
HOUSING AND REDEVELOPMENT AUTHORITY OF BENSON
combine two small units to creat one large unit, will convert 8 small apt. into 4 larger marketable units
Rehabilitation of Public Housing North Star Apartments High Rise including:  rehab of 1st and 2nd floor common areas:  replace ceiling tiles, floor coverings, wall coverings, electrical-lighting fixtures, window treatments, install 5 ventilator
Modernization of both elevators to bring them up to code with the new state requirements. Replace apartment entry door locks with deadbolts.
The HRA of Little Falls, Minnesota is implementing the following activities using Capital Fund Recovery Act funding:  100 units of the PINE GROVE MANOR APARTMENTS (MN042000001)public housing development are being rehabilitated.
-Convert 3 efficiency units into 2 1 bedroom units.  This funding can provide employment for architects, engineers, and construction. -Replacing exhaust fans on roof. -Replacing outside lights around complex. -Replacing concrete on some existin
Conduct modernization activities at a public housing high-rise development.This funding can be expected to result in employment for engineers, electricians and HVAC specialists and will substantially modernize the public housing development.
HOUSING AND REDEVELOPMENT AUTHORITY OF CROSBY
Recarpeting/Install entrance canopy- carrying out caiptal activities at public housing development
CASS LAKE HOUSING AND REDEVELOPMENT AUTHORITY
Comprehensive modernization of family units;replacement of bathtubs, vanities and flooring in bathrooms and interior doors. Tail end of 07,08 CFP Project. Also siding and window replacement at 5 single family homes
OLMSTED COUNTY HOUSING AND REDELOPMENT AUTHORITY
FARIBAULT HOUSING AND REDEVELOPMENT AUTHORITY
Replacement of windows in family development with energy efficient windows. This funding can be expected to result in providing
OTTER TAIL COUNTY HOUSING & REDEVELOPMENT AUTHORITY
Mechanical installation of Central A/C and Air Exchangers
Replace Shingles on 2 Apartment Buildings; a 6-Plex ans 4-Plex.  This project will provide employment for archetects, construction workers, retail sales, and product manufacturers.  In addition the funding can be expected to substantially incre
Pine Mountain Apartments, Reshingle 2 Apartment Buildings
Conduct moderization activities at Park Road Plaza.This funding can be expected to result in providing employment.
WASHINGTON COUNTY HOUSING & REDEVELOPMENT AUTHORITY
The Washington County HRA is implementing the following activities using Capital Fund Recovery Act funding: 56 Units of SCATTERED SITE (MN212000001)public housing development is being rehabiliated.
Capital Fund SCATTERED SITE Energy Efficiency Project
546 - (Combo Loan & Grant) Combination W&W - 09/10 Stimulus
Village of Jane Sewer Project- installing a wastewater collection system and pump stations to transport wastewater to Village Wastewater Co. in Bella Vista, Arkansas for treatment.
Waterline replacements and modifications at the well houses and chlorine buildings.  The waterline replacements will consist of approzimately 23000 lineal feet of 6 inch Class 160 PVC pipe and 18200 lineal feet of 4 inch Class 160 PVC pipe.  Th
King Louis Square I Grant award to install solar panels to provide common space electric service for public housing units. Final HUD approval incorporated a water harvesting component.
comprehensive modernization of senior bldg; expand prking; clean,repair exterior of bldg.
conduct moderniation activities at the Bethany Housing Authority devolopment.
The goals of this project are to understand the concurrent development of the acoustical cues to sound source location and the neural circuits that encode them. All cues for localization can be captured in measurements of head related direction
Developmental Studies of Sound Localization Mechanisms
Language development in typical children follows specific developmental sequences and demonstrates inherent biases at certain stages.  It is not known to what degree language development in children with autism follows the same development rule
Language Development and Outcome in Children with Autism
Department of Psychology 406 Babbidge Road
Our long-term goal is to understand how voltage-gated ion channels regulate hair cell excitability, influence sensory processing in the cochlea, and contribute to normal and abnormal auditory function. Calcium-sensitive potassium (BK) channels
BK channel regulation in auditory hair cells
Among the five senses, hearing is fundamental for acquiring language, communication, and navigating through our environment. An estimated 28 million Americans are deaf or hearing impaired due to genetic factors, sound-induced trauma, aging or p
Development of the Mouse Cochlea Database
ELECTROPHYSIOLOGICAL SIGNATURES OF LANGUAGE IMPAIRMENT IN AUTISM SPECTRUM DISORDE
The overall goals of this project are to (A) obtain behavioral estimates of tinnitus induced by salicylate or noise exposure, (B) identify the changes in neural activity associated with salicylate or noise-induced tinnitus using MicroPET imagin
ARRA:  Animal Models of Tinnitus, Brain Imaging and Therapy
The purpose of the supplement is to modernize current research equipment and to enhance energy efficiency in the conduct of the parent project, Development and Adaptive Behavior in Young Children with Hearing Loss. Specifically, support is requ
Development and Adaptive Behavior of Young Children with Hearing Loss
ARRA administrative supplement to R01 DE007389.  Regenerative medicine is the process of generating new functional tissues to repair or replace a damaged organ due to disease or damage. Salivary gland tissue regeneration would represent an impo
The Regulation of Salivary Gland Regeneration by P2Y2 Nucleotide Receptors (ARRA administrative supplement to R01 DE007389)
Nonsyndromic cleft lip and palate (NSCLP) is a common birth defect affecting approximately 4,000 newborns each year in the US and a million worldwide. Multidisciplinary approaches have improved the care of these children but long-term problems
MAPPING NONSYNDROMIC CLEFT LIP AND PALATE GENETIC LOCI
About 75% of birth defects involve the head, face, and oral tissues. Although orofacial clefts and other craniofacial malformations have clear environmental and genetic causes, insufficient information exists concerning the mechanisms of cranio
The Role of AP-2 in Craniofacial Development
To test this hypothesis we propose three specific aims. These are to: 1) define, using in situ hybridization and mouse-specific antibodies, the spatiotemporal expression patterns for Cd63, Anxa2 and Lampl within the murine developing incisor t
has inspired the NIDCR to issue a program announcement (PA-01-121) indicating a high priority status for this subject. After 60 years of community water fluoridation we still do not know how much F is required to prevent caries. This may be be
FLUORIDE REQUIREMENTS FOR THERAPEUTIC EFFICACY
Periodontitis results in loss of tooth-supporting tissues including bone, cementum, and periodontal ligament (PDL), ultimately leading to tooth loss if left untreated. Dental tissue loss represents the second largest patient population next to
PERIODONTAL ENGINEERING USING BIOMIMETIC NANO SCAFFOLDS
Nano forms of hydroxyapatite, other calcium phosphate compounds, and additional bioactive inorganic materials will be prepared by a newly developed method, employing either a spray drying or a flame pyrolysis technique in such a way that (1) ta
The supplement is to increase the tempo of research that is embodied withing the aims of the parent grant and to replace aging/failing equipment that is integral to the research activities of the grant.  This support will enable the development
Aging and Gatigue Crack Growth in Dentin
In order to generate the craniofacial skeleton, neural crest progenitors need to adopt one specific fate verses another. It is the long-term goal of my laboratory to determine the molecular mechanisms that regulate cell fate determination of ne
THE ROLE OF prdm1 IN BRANCHIAL ARCH DEVELOPMENT
Diabetes-enhanced experiment periodontisis. To be used for the purchase of equipment.
Chronic pain, including chronic orofacial pain, remains unsuccessfully treated in a large number of patients. Furthermore, the loss of analgesic efficacy with chronic administration of frontline analgesic drugs, such as morphine, severely limit
Optoid Analgesics:  Modulation of Trigeminal & Spinal Glial Activation  (supplement to DE017782)
Peripheral neuropathic pain arises from diverse changes in the peripheral and central nervous systems that include a reciprocal interaction between the immune and nervous systems. We find from a microarray expression profile analysis that immun
Evolution of vertebrates has been intimately linked to the advent of the neural crest, a migratory and multipotent cell population that gives rise to many defining characters of vertebrates, including a well-defined head and peripheral ganglia
EVOLUTIONARY ORIGIN OF VERTEBRATE NEURAL CREST GENE NETWORKS
Genetic Determinants of Physiological Responses to Fluoride in Bone The supplement will be used to support undergraduate students during their participation in research related to the active parent grant and to accelerate the accomplishment of
Genetic Determinants of Physiological Responses to Fluoride in Bone
Craniosynostosis, the premature fusion of one or more cranial sutures (most commonly those of the calvaria), is a common malformation occurring in 1 out of every 2500 live births, and shows marked variation of cranial phenotypes. Our aims are t
PHENOGENETICS OF SKULL AND BRAIN INTEGRATION IN CRANIOSYNOSTOSIS
The overall goal of this project was employ two student workers and have them contribute to the success of our parent grant related to ameloblastin function.  Much of the resilient properties of the periodontium are facilitated by a non-mineral
Ameloblastin Function in Periodental Development
.  The ultimate goal of this research project is to develop novel biologically based, dental and craniofacial skeletal repair and regeneration therapies in humans.  We hypothesize that improved knowledge of tissue engineering strategies to reli
Dental Stem Cells and Tooth Tissue Engineering
The overall goal of the parent research project is to employ both biochemical and genetic tools to elucidate basic mechanisms that control development stage-specific expression of the vertebrate B-type globin genes. The focus of this project is
Globin Gene Expression during Erythroid Differentiation
This is a continuation of a project, for which the long-term goal is to define T cell effector mechanisms at the level of the small intestinal epithelium, by characterizing the stimulatory and costimulatory signals that drive intestinal intraep
resection model that mimics human SBS (Aim 2, 60% jejuno-ileal resection + cecectomy), and varying types of enteral and parenteral nutrients. We will determine if the intestinotrophic response to GLP-2 infusion is reduced by functional ablatio
ARRA - Parenteral Nutrition: Intestinal Metabolism/Adaptation
Studies outlined in the revised competing renewal are aimed at understanding the physiologic and therapeutic effect of activating ADO A3 receptors (Rs) in experimental models of colitis. Three specific aim's are addressed in distal colon, the t
(ARRA) Purinergic regulation of enteric neural reflexes
The goal of this project is to determine the functional adaptation and consequences of salt intake on endothelial cell function in the vasculature and the kidney. By defining the signal transduction pathway in endothelial cells, this applicatio
MECHANISMS OF SALT-SENSITIVE HYPERTENSION AND HYPERTENSIVE NEPHROSCLEROSIS
This administrative supplement to parent grant, DK 48215, intends to accelerate the pace of the animal studies, murine outlet obstruction experiments, which are major components of Aims 2 and 3 of the parent grant. Funds are sought for the purp
Molecular Analysis of Collagen in Non-compliant Bladders
EryP are the first differentiated cell type to form in the mammalian embryo and play a vital role in oxygen delivery and in generating shear forces necessary for normal vascular development. Despite their abundance and indispensable functions,
ERYTHROID DEVELOPMENT IN THE MAMMALIAN EMBRYO
This is an administrative supplement request for R01 DK052446-11, being submitted in response to NOT-OD-09-056, in compliance with specific guidelines from NIDDK.  The title of the parent grant is ?Mechanisms of Regulation of NHE-1? with a curr
, we propose as the central hypothesis of this application that a significant number of human disease genes will be linked to novel genes that are currently represented in the cilia proteome but are yet uncharacterized. We have exploited the ze
Genetic analysis of Zebrafish kidney development
Summary narrative of ARRA funded project activity/milestones: Research design and methods and data analysis for the summer research supplement: 1. General Research plan: The summer hs student, undergraduate student, and hs science teacher work
DNA sequences impact estrogen and antiestrogen activity
Our long-term objective is ,to understand the pathophysiology of autosomal dominant polycystic kidney disease (ADPKD) as a basis for therapy. Autosomal dominant polycystic kidney disease (ADPKD) is the most common lethal monogenic genetic disea
Molecular pathophysiology of PKD2 mutations
MORBIDITY AND MORTALITY RELATED TO GASTRIC BYPASS SURGERY This four-year renewal application will test the hypothesis that Roux-en-Y gastric bypass (RY-GBP) surgery reduces long-term (5 1/2-year follow-up) morbidity from severe obesity. This wi
MORBIDITY AND MORALITY RELATED TO GASTRIC BYPASS SURGERY
. We discovered that a single transcription factor, CP2L1, induces the conversion of metanephric mesenchyme into tubules. We discovered this pathway by analyzing genes that were expressed in a synchronous fashion when we stimulated metanephric
Cytokines Convert Epithelial Precurors to Nephrons
The award is entitled TGF-beta regulation of intestinal epithelial cells and is a supplement to and existing R01 grant (R01DK059656).  This supplemental ARRA funding layers seamlessly onto our laboratory research project investigating the effec
TGF-beta Regulation of Intestinal Epithelial Cells
The primary objective of this extension to the parent proposal is to determine the pro-fibrotic mechanism by which ANG II leads to tubulointerstitial fibrosis. Founded on the tenet proposed in the parent grant that renin secreted from mast cel
Mast-Cell Renin and Local ANG II Formation
The long-term goal of the parent grant is to determine the structural and functional determinants of paracellular permeation in epithelia. We previously developed a model using inducible overexpression of claudin-2 in MDCK I cells to study the
In our previous work, we suggested that reductions in peritubular capillary (PTC) density compromised blood supply of post-ischemic kidneys, impairing the ability to deliver oxygen to the renal parenchyma and predisposing the fibrotic process (
Long Term Effects of Acute Renal Failure
The long term goal of this project is to understand the molecular mechanisms responsible for altered glucose homeostasis during highly active antiretroviral therapy (HAART). The metabolic changes that occur in association with the use of HIV pr
MECHANISMS FOR ALTERED GLUCOSE HOMEOSTASIS DURING HAART
DESCRIPTION (provided by applicant): Iron has an essential role in many biological processes, including DMA synthesis/respiration, the tricarboxylic acid cycle, oxygen transport, heme synthesis and photosynthesis. But iron can also be toxic due
GENETIC ANALYSIS OF IRON HOMEOSTASIS IN C. ELEGANS
Systemic Lupus Erythematosus (SLE) is a heterogeneous disorder characterized by autoimmunity and the development of progressive immune complex renal disease. The pathogenesis of SLE is complex and multi- factorial; substantial clinical and expe
C3AR AND C5AR MODULATE T-CELL RESPONSES IN THE MRL MOUSE
The goal of the original application is to define and characterize the mechanisms responsible for the intrarenal augmentation of angiotensinogen (AGT) expression by angiotensin II (Ang II).  The central hypothesis of the original application is
Intrarenal Augmentation of Angiotensinogen by Ang II
.  The overall project is aimed at addressing the hypothesis that PDX-1 is involved in establishing and maintaining epithelial cell gene expression patterns along the anterior-posterior axis of the small intestine and functions to differentiall
PDX-1 REGULATION OF INTESTINAL PATTERN FORMATION
In a prospective longitudinal study, it is hypothesized that the built environment's walkability will impact the social environment's collective efficacy, and that these environmental variables together will influence physical activity. Control
HISPANICS, BUILT ENVIRONMENT & METABOLIC SYNDROME.
This award is issued in response to Notice OD-09-060, Recovery Act Administrative Supplements Providing Summer Research Experiences for Students and Science Educators.  Although the pancreas is a relatively small organ, tucked away in a corner
WNT/BETA-CATENIN SIGNALING IN EXOCRINE PANCREAS DEVELOPMENT AND REGENERATION
The present supplement application seeks support for a 2 summers of paid research experience at The Scripps Research Institute for an undergraduate with very high potential for a biomedical research career, a current junior at the University of
Galanin Control of Food Intake: Molecular, Neuroanatomical and Behavioral Bases
A part-time undergraduate student that is from an underrepresented population in science (African-American) was hired for work on this project. Her efforts focused on immunohistochemical detection of specific proteins in the hypothalamus that m
Defining the progenitor cell niche of the developing kidney (competitive revision). The purpose of this award is to understand pathways that regulate kidney progenitor cells, to ultimately advance the development of cell based therapies for kid
Defining the progenitor cell niche of the developing kidney
Kidney disease is huge worldwide health problem that is becoming increasingly prevalent. Primary glomerular disease, both acquired and genetic, represents a significant proportion of these cases, due in part to the incidence of diabetic nephrop
Project Narrative. A reduced ability of the pancreatic hormone insulin to trigger tissue uptake of blood sugar is an early event in the course of development of type 2 diabetes mellitus (T2DM). Relatively poor fat combustion by fasting muscle i
Identification of Muscle-Specific Biomarkers of Fatty Acid beta-Oxidation
USDA-ARS Western Human Nutrition Research Center
The supplement is to fund an undergraduate student to spend 8 weeks in my laboratory this summer investigating the terminal differentiation of primitive erythroid cells. The summer research experience is designed to encourage undergraduate stud
INITIATION OF MAMMALIAN EMBRYONIC HEMATOPOIESIS
The majority of patients with polycystic kidney disease (PKD) die due to cardiovascular complications such as hypertension, aneurysm, hemorrhage, etc.  Our recent data indicate that the cardiovascular hypertension in PKD is associated with func
The Roles of Primary Cilia in Cardiovascular System
Polycystic kidney disease (PKD) is a systemic nephropathy characterized by progressive bilateral renal cyst formation that results in a gradual decline in renal function. Although it is most commonly categorized as a kidney disease, the majorit
THE ROLES OF PRIMARY CILIA IN CARDIOVASCULAR SYSTEM
Gastric bypass surgery (GBS) is an exceptionally successful therapy for morbid obesity and type 2 diabetes. GBS patients typically lose 25-35% of total body weight, demonstrate improvements in medical co- morbidities, and sustained weight loss
NIH GASTRIC BYPASS SURGERY ALTERS THE REGULATION OF FOOD REWARD (ADMIN SUPP)
This award is a competitive supplement for a previously awarded grant. Our initial grant aims at measuring longitudinally (over more than a 20 year period) biomarkers  of endothelial cell dysfunction, inflammation and clotting/fibrinolysis fact
Biomarkers of Vascular Disease Progression in Type 1 Diabetes Mellitus - Competitive Revision
This administrative supplement will provide funds for the purchase of an Applied Biosystems 7500 Real-Time PCR system and salary support for a newly hired technician. The parent grant investigates how mutations in chymotrypsinogen C (CTRC) incr
The goal of the supplement fund is to develop a Fourier domain optical coherence tomography (FD-OCT) system that will achieve high resolution and high speed simultaneously.  The proposed research will accelerate the translation of this technolo
This administrative supplement request seeks to accelerate software development for a system that provides fully-automated processing and analysis of volumetric metabolite images. This aim directly supports all Specific Aims of the parent grant
PARTNERSHIP FOR MR SPECTROSCOPIC IMAGING DATA PROCESSING.
The overall scope of the parent project (5R01 EB 001659) is to develop and evaluate advanced patient-monitoring and clinical decision-support concepts that will improve the efficiency, accuracy, and timeliness of decision-making in critical car
Integrating Data, Models, and Reasoning in Critical Care
DESCRIPTION (provided by applicant): A biomimetic strategy is proposed to develop a new class of adhesives for orthopedic medicine, particularly joint fractures with multiple bone fragments. The adhesive is modeled after a natural underwater ad
BONE ADHESIVE MODELED AFTER THE SANDCASTLE GLUE OF P. CALIFORNICA
. The proposal is targeted at user support, software extensions, and the development of an FDA approved image-guided application and initial clinical trial. This is a three year project with four specific aims: 1. Support the IGSTK user communi
CONTINUED DEVELOPMENT FOR THE IMAGE-GUIDED SURGICAL TOOLKIT PROJECT (IGSTK)
Recent advances in confocal microscopy have demonstrated the potential of optical imaging to provide molecular images with sub-cellular resolution. In this proposal, we extend our work in high resolution confocal microscopy, based on a much sim
INTEGRATED OPTICAL NEEDLE (ION) FOR CELLULAR AND MOLECULAR IMAGING OF CANCER
CRCNS: Integrated Empirical and Multiscale Modeling of Human Sleep Spindles. The overall goal of the proposed research is to determine how brain events at the biophysical level in the human brain influence the macroscopic recordings outside the
CRCNS: INTEGRATED EMPIRICAL AND MULTISCALE MODELING OF HUMAN SLEEP SPINDLES
Chronic kidney disease (CKD) is a major global public health problem. Environmental and occupational exposure to lead and cadmium may increase CKD risk independently and in conjunction with established causes, such as diabetes and hypertension.
ENVIRONMENTAL & GENETIC RISK FACTORS FOR RENAL FUNCTION
This competing renewal application aims at investigating the hypothesis that exposure of human melanocytes to ultraviolet radiation (UV) and/or the physiological agonist 1-melanocyte stimulating hormone (1-MSH) or antagonist agouti signaling pr
Supplement for Signaling Pathways for UV-Induced Melanogenic Response R01 ES009110
Chronic intoxication with manganese (Mn) is the cause of a degenerative movement disorder, termed manganism, with clinical features that resemble Parkinson`s disease. Recent findings suggest that injury to this region of the brain involves pert
Manganese and basal ganglia dysfunction: role of NO
The proposed supplement to the ongoing study of chilhood asthma is designed to accelerate the rate of recruitment of study subjects.  Parents will be administered a standardized asthma questionnaire (ISAAC) to determine presence and frequency o
Characterization of Floor Level Aerosol (PM) Exposure and Childhood Asthma
The ARRA funded a Research Supplement to Promote Diversity in Health-Related Research that was used to provide employment for a recent college graduate.  She conducted research on the interaction of genetic and environmental risk factors in aut
Subproject for Institution # 018207: Epigenetic Interaction of MECP2 and Organic Pollutants in Neurodevelopment
Conduct extior modenization of Public Housing developement. This funding can be expected to provide employment for general contractors.
The ARRA funds are for roof replacement on twenty-nine (29) low income housing units.
Capital Fund Grant Remodel a public housing unit to be 504 compliant and added a playground.
THOMAS HILL PUBLIC WATER SUPPLY DISTRICT 1
Funds will be used to build booster pump station, elevated storage tank, and to replace undersized water main.
Randolph CO. Public Water Supply District #1
SUNFLOWER COUNTY BOARD OF SUPERVISORS INC
Purchase 4 F150 pickups for the Sheriff's Department for law enforcement and patroling over the entire county.  This report was submitted correctly on October 7, 2009.  Tommie James from USDA, Rural Development asked me to deactivate it this mo
Grant from Rural Development to be used in conjunction with a Rural Development Loan and CDBG funds to construct a Health and Human Services Complex.
Humphreys County Health and Human Services Complex
This is a Community Programs grant made to construct a new elevated water tank, drill a new water well, & add new distribution lines.
RUS Grant to drill a water well and construct an elevated water tank.
Purchase of two (2) fully equipped patrol cars
American Recovery & Reinvestment Act of 2009 to assist Capital Funds for improvement of low income public housing
MERIDIAN HOUSING AUTHORITY FOR THE CITY OF MERIDIAN
Conduct modernization activities as various Public Housing Developments.  This funding can be expected to result in providing employment for architects and engineers, construction workers and product manufacturers.  In addition this funding can
HOUSING AUTHORITY OF THE TOWN OF RICHTON, THE
ARRA funds will be utilized at Project 67-1 for kitchen renovation and replacing heating coils in Project 67-1 & 2 under Amp 01.This funding can be expected to result in providing employment for architects and engineers, construction workers an
HOUSING AUTHORITY OF THE, CITY OF LOUISVILLE
ARRA funds are being utilized at North Court  project 79-001 for comprehensive renovation of the interior of 4 units.  Paving of parking lot improvements at 79-003.   Installation of 264 new windows at 79-003.  Roofing in 79-003 for 54 units.
Rural Utilities Loan and Grant to extend water lines to serve an additional 30 households in rural Washington County.
Swiftwater Development Water Expansion Project
The purpose of this project is to drill a water well, extend water lines and construct a new office facility.
USDA Rural Utilities Service Water Loan and Grant Program
For the purchase of a fire truck with fire-fighting and personal protective equipment, as well as an excavator for use in Benton County 2nd District.
USDA RD Community Facility Benton Co. 2nd District Fire Protection & Maintenance Equipment
EASTERN PLAINS ECONOMIC DEVELOPMENT CORPORATION
Revolving loan fund to be utilized in the Eastern Plains Economic Development District.  The purpose of the loans will be to assist businesess with start-up, growth, or stabilization to create and/or retain jobs.
The Hi-Line Retirement Center is proposing to construct a project that would include a new 9,350 square feet (sf) 12 unit Assisted Living facility, a new 1,500 sq kitchen, a remodel of the existing kitchen area for additional dining and activit
Renovations at Hi-Line Retirement Center
Water System Improvement Project - This portion is the grant component of the District's water project which involves the replacement of majority of the rural distribution system within the Loma County Water and Sewer District, installation of
Supplement  modernization activities at various public housing sites.  Work included Design; Invitation to Bid; Administration; Replacement of shingle roofs on 40 buildings which affected 170 units; and the Replacement of 130 furnaces with ener
Invest in public transportation by purchasing four new thirty-foot buses for replacement
Invest in public transportation by rehabilitating a Bus Wash Facility, replacing two high maintenance low-floor buses that have exceeded their useful life of twelve years, the replacement of one Paratransit Van that had exceeded its useful life
The Navy is supporting the development of hybrid motor-generators for the DDG-51 class of destroyers and for future combatants.  AMSC was awarded a contract to:  1) Assess and validate the Navy's interface & performance specifications from vend
WICHITA: BROADWAY-CENTRAL TO 12TH STREET
Federal projects P142041, N331025,N202062, N341105, N303049 and N345089 combined,  including selective site and building demolition, additions and other upgrades to the existing rest area  buildings, including mechanical, electrical and plumbin
Federal projects N345095, N345080 and N345101 combined, involving grading, placing crushed  base and bituminous pavement leveling and surfacing, guardrail and miscellaneous work at two  locations on US 16/30 and WYO 789 just north of Basin, in
The work includes the construction of a pre-engineered temporary satellite pharmacy with drive up functions, transaction windows and an option for a pneumatic delivery system to vehicles. The buildings will have metal wall & roof panels, interi
Contract for Design Build Services, ARRA - Hanger 110 Modernization, Naval Air Station, Patuxent River, Maryland
The purpose of this project is to install facility energy improvements in various buildings.  The location is the Naval Surface Warfare Center, Indian Head, MD.  The outcome of this project will improve energy effeciency in all effected buildin
Replace emergency generator at Building 2737, NAVFAC Midwest, Crane, Indiana
Berth 7 Repairs Portsmouth Naval Shipyard Kittery, ME
Replace HVAC and modernize Building #343.
Repair Steam Lines Naval Station Norfolk
ARRA, HVAC/Mechanical.Electrical/Roofingand Windows.  Interior and Exterior Repairs to Building AS3905 & AS4106
AS-4157 Work includes removing existing and providing new flooring, ceilings, toilet fixtures, HVAC systems, lighting, and roof covering and repainting all normaly painted surfaces, and other related incidental work. Protect existing vegetation
NAVFAC Atlantic issued this contract to install Photovoltaic (PV) systems and Building Integrated Photovoltaic (BIPV) systems on building rooftops, carports and ground-mounted PV arrays at various Naval Facilities Engineering Commands (FEC) for
Provide A&E Services for the design and project documentation for the construction / alteration to the Naval Hospital at NAS Jacksonville
RECOVERYPROJECT#::PE1079M::RP# REPAIR GAS PIPE 52 AREA (BS20) MCB CAMP PENDLETON, CALIFORNIA.
Oil and Gas Pipeline and Related Structures Construction
It is the objective of Enterprise Engineering, Inc.'s statement of work to assist NFESC in the development of certification and approval protocols for the purpose of reviewing and evaluating materials and systems compatibility in the storage an
Delivery order for engineering studies in support of building renovation/modernization.
RECOVERYPROJECT#::TMA-N14::RP# RESTORE MYCOLOGY CLINICAL SPACES, NMCSD, SAN DIEGO, CA.
REPLACE ROOF AT BLDG. 60196 IN SAN CLEMENTE ISLAND, CA
Repave Runway 16-34, Taxiway 1-19 and Aprons at Pacific Missile Range, Barking Sands, Kauai, Hawaii.  The work includes, but is not limited to, sawcutting and cold mill planing up to 4' of the existing asphalt concrete pavement of the runway, t
Install Photovoltaic Systems (RM09-1363), Navy Installations, Islands of Oahu and Kauai, Hawaii.   Replacement of roofing and installation of Photovoltaic Systems on 10 buildings at PMRF and 5 buildings at NAVSTA PH.   Provide Post Construction
Finalized VSD, motor and magnetic bearing specifications.  Specifications submitted to Navy for review and approval.  Navy approved specifications.  RFQ?s issued to vendors.  Responded to vendor questions and clarifications regarding RFQ?s. Quo
REPAIR UTILITY INFRASTRUCTURE IN WAREHOUSE AREA 2
Whole Navy Operational Center Facility Modernization, EL Paso, TX
Design and build P761 Child Development Center at Naval Station Mayport, Florida
Modernize Parking Lot Building 30 at Naval Air Station, Joint Reserve Base, New Orleans, LA.
The Division of Environmental Quality will address upland sources of sedimentation for the recovery of coral reefs within Laolao Bay. The Division of Environmental Quality will also protect sea turtle nesting habitat along Laolao Bay. Proposed
Laolao Bay Road & Coastal Management Improvement Plan
The Recovery Act-Muskegon Lake Great Lakes Area of Concern Habitat Restoration Project will restore fish and wildlife habitat and degraded benthos Beneficial Use Impairments (BUIs) in the Muskegon Lake Great Lakes Area of Concern.  The proposal
Recovery Act - Muskegon Lake Great Lakes Area of Concern Habitat Restoration Project
502-Engineered Log Jams; 503-Floodplain Dike Removal; 504-Bosco Creek/Lower Elwha Road Culverts; 505-Lower Elwha River Flood Plain Revegetation; 506-Weir-Adult Numeration
This proposal focuses on floodplain restoration, revegetation and monitoring actions complementary to Elwha dam removal.  The Floodplain Restoration proposal focuses on restoration of habitat forming processes in the lower river through the rem
Elwha River Floodplain Restoration, Revegetation and Monitoring
The Qwuloolt Estuary Restoration Project represents a broad-based interagency and community effort to restore historic tidal processes and a functioning estuary intertidal marsh system to 350 acres of isolated floodplain within the lower Snohom
Qwuloolt Estuary Restoration Project, Snohomish River Estuary, Puget Sound, Washington: Levee removal to restore hydrologic connection ot 350 acres of historic wetland and floodplain
The Klawock River project will restore salmon habitat by constructing a fish passage structure through an earthen causeway where it crosses the Klawock River estuary and is the foundation for the Klawock-to-Hollis highway. Prior to the construc
Salmon Passage & Habitat Restoration: Klawock River, Southeast Alaska
Through a partnership of federal, state, and local agencies, as well as several local non-profit organizations, approximately 257 acres of tidal flats, salt marsh, subtidal, and native upland habitat will be restored in and around south San Die
This grant will benefit participants of the California Conservation Corps (CCC) by providing opportunities for job training, personal development, conservation service, fish and stream habitat restoration, watershed improvement and restoration
Coastal Fisheries Restoration Project Partnership
NAVAJO ENGINEERING & CONSTRUCTION AUTHORITY
Complete construction of 10800' of 10' and 42800'of 8'PVC watermain, one well pumphouse w/submersible pump installation, and one booster station that will benefit 247 homes.
Complete pressure testing of 34000' of waterline, construct a solenoid valve vault with controls and telemetry, a booster station with a powerline extension, electrical controls and telemetry controls which will benefit 62 project homes.
Complete construction of 2400' of 2' PVC waterline that will benefit 11 project homes.
Complete construction of 38000' of 4' PVC and 1800' of 2' PVC waterline that will benefit 30 project homes.
This project will contribute funds to complete the construction of 4,500 feet of 4-inch and 1,000 feet of 2-inch PVC waterline that will benefit 12 project homes.
This project will replace approximately 3700'of 6' PVC waterline in Blanco Wash with an equal amount of 6' HDPE pipe.  The HDPE pipe is proposed for installation parallel to the existing PVC pipe at a depth of approximately 8'.  The installatio
EPA provided IHS $668,750 of Clean Water Act Indian Set Aside funds through Interagency Agreement DW-75-95765901-0 for this project.  Project scope: This project will improve the sanitation facilities for 101 homes in the subject chapters. Fail
EPA provided IHS $711,460 of Clean Water Act Indian Set Aside funds through Interagency Agreement DW-75-95765901-0 for this project.  Project scope: This project will replace approximately 56 septic tank/drainfield systems in the Fort Defiance
EPA provided IHS $456,250 of Clean Water Act Indian Set Aside funds through Interagency Agreement DW-75-95765901-0 for this project.  Project scope: This project will replace individual sewage disposal systems for 32 homes.
EPA provided IHS $75,000 of Clean Water Act Indian Set Aside funds through Interagency Agreement DW-75-95765901-0 for this project.  Project scope: This project will replace nine failed septic tanks/drainfield systems. All of these homes have f
EPA provided IHS $165,630of Clean Water Act Indian Set Aside funds through Interagency Agreement DW-75-95765901-0 for this project.  Project scope: This project will replace twenty septic tanks/drainfields. All of these homes have failed indivi
EPA provided IHS $189,580 of Clean Water Act Indian Set Aside funds through Interagency Agreement DW-75-95765901-0 for this project.  Project scope: This project will construct 1,600' of 8' sewer main and 5 manholes to benefit twenty-five homes
EPA provided IHS $723,960 of Clean Water Act Indian Set Aside funds through Interagency Agreement DW-75-95765901-0 for this project.  Project scope: This project will renovate 6,600-feet of 8-inch and 12-inch of sub-standard sewer lines and fou
EPA provided IHS $203,130 of Clean Water Act Indian Set Aside funds through Interagency Agreement DW-75-95765901-0 for this project.  Project scope: This project will remove sewage sludge from the Kayenta community waste water treatment plant.
EPA provided IHS $116,670 of Clean Water Act Indian Set Aside funds through Interagency Agreement DW-75-95765901-0 for this project.  Project scope: This project will construct de-chlorination facilities at the Kayenta community waste water tre
This supplement will provide summer funding for undergraduates to participate in research. Students will assist in the animal experiments and cell culture exeriments as a part of the parent grant. This award will accelerate the successful compl
Mechanisms of UV-induced skin carcinogenesis
Adverse human health effects due to occupational and environmental exposure to nanomaterials are a major concern and a potential threat to their successful commercialization and biomedical applications. Realization of their commercial potential
CHEMICAL, STRUCTURAL, AND SUPERSTRUCTURAL DETERMINANTS OF NANOCARBON TOXICITY
The developing central nervous system is particularly vulnerable to environmental toxicants such as heavy metals. While lead (Pb) poisoning has been extensively studied, the neurotoxicities and dose-effect relationships associated with other he
Metal exposure and children's preschool Neurodevelopment
This supplement accelerates the tempo of research on the three specific aims of the grant by 1) hiring a new research technician who will help work on all three specific aims to move more quickly; 2) hiring a PhD graduate student whose disserta
The overall objective set forth in the currently funded project was to study the role of the heme oxygenase (HO) system in regulating the corneal inflammatory and repair response. This was based on preliminary studies showing that the HO system
Corneal Arachidonate Metabolites via Cytochrome P450
The purpose of this grant is to identify susceptibility genes involved in the pathogenesis of keratoconus (KC). We will achieve our goal by: 1) refining criteria for the early detection of KC using videokeratography and wavefront Zernike variab
Retinal neovascularization is the leading cause of blindness in the United States among working-age adults (diabetic retinopathy) and infants (retinopathy of prematurity). An important event of the angiogenesis cascade is the breakdown of the c
EXTRACELLULARY PROTEINASES IN OCULAR NEOVASCULARIZATION
changes in position invariance are temporary, or if they last for many days or weeks.   This award will have an immediate stimulatory effect on the US economy because: 1) it will support a new scientist-in-training, 2) it will enable retention
Visual Object Processing in the Inferotemporal Cortex
The goal of this project is to increase understanding of retinal iron homeostasis through the study of transgenic and knockout mice. These mice are expected to develop retinal degeneration with features of age related macular degeneration, serv
Successful development of a functional eye requires not only cell-differentiation programs that specify various retina cell types, but also size-control mechanisms that determine the number of cells in the retina. The long-term scientific goal
CONTROL OF CELL NUMBER IN DEVELOPING RETINA
the thalamus. The health relatedness of this research is that study of how the normal, healthy brain works is how we come to understand the human condition in health and in illness.
Funds from this administrative supplement are being used to purchase the CFX96 Real-Time PCR Detection System (Bio-Rad Laboratories, Hercules, CA) including a computer, software, and essential SYBR green fluorescence reagents, as proposed in th
MOLECULAR MECHANISMS REGULATING VMD2 EXPRESSION
This supplement provides support for one postdoctoral scientist to accelerate the pace of the research. The neural competition underlying perceptual alternations during rivalry is believed to be closely related to the strabismic suppression. He
Traveling Waves in Visual Cortex during Binocular Rivalry
This supplement request is to support the hiring of an outstanding postdoctoral research associate who will take on a central role in carrying out fMRI studies of motion perception, Aim 2 of this R01 project. The PI has lab members actively wor
Neural Representation of Features in the Human Visual Cortex
The objective of the parent grant is to develop an eye movement model that can predict task-dependent fixation patterns in human observers, and to apply this same model to study eye movement behavior in patients with macular degeneration and ot
CRCNS: Where to look next? Modeling eye movements in normal and impaired vision
The long-term goal of our research is to elucidate the mechanistic basis of ocular morphogenesis in vertebrates. During ocular morphogenesis, the optic primordia undergo a complex series of morphogenetic movements that ultimately result in a bi
GENETIC REGULATION OF EYE DEVELOPMENT IN ZEBRAFISH
This supplement will accelerate progress on all three Aims of my funded NEI grant, Role of cerebellar parallel fibers in saccade accuracy, R01 EY018585, Farrel R Robinson, P.I.  Aims 1 and 2 include quantitative analysis of voluntary rapid eye
Role of cerebellar parallel fibers in saccade accuracy
Driving of the personal vehicle is the primary and preferred mode of travel for older adults in the U.S. More than fulfilling the critically important 'getting around' or mobility function, driving in older adults profoundly impacts health stat
OLDER DRIVERS: AN EVIDENCE-BASIS FOR LICENSURE STANDARDS
One major group of general aims of our research is to identify N-terminal acetyltransferases (NATs), their subunit composition, their substrates, their functions and their interactions. In general, much of our research is hampered by the lack o
REGULATION AND GENE EXPRESSION OF YEAST CYTOCHROME C
The long-term goals are to understand the biochemical mechanisms, physiological regulation, and biological roles of initiation factors that recruit mRNA to the ribosome, a process that determines rate of protein synthesis, spectrum of mRNAs tra
REGULATION OF EUKARYOTIC PROTEIN SYNTHESIS INITIATION
pathway in the well-studied lactose repressor protein (LacI). In LacI function, ligand binding information must flow through the protein structure between the widely separated inducer and DNA binding sites. Our ultimate goal is an atomic-level
ALLOSTERIC TRANSITION IN LACTOSE REPRESSOR PROTEIN.
) in human disease. In the parent grant (R01 GM22942), we are testing the central hypothesis that cellular SLs are critical for the regulation of certain intracellular transport pathways, in part through formation of membrane domains. A major f
Intracellular Translocation and Metabolism of Lipids
We will use mass spectrometry to discover proteins or protein modifications on the cell surface that are selective for dividing or dying cells. These will provide biomarkers for understanding how anti-mitotic drugs work or fail in cancer therap
Cytoskeleton polymerization dynamics in the cell cycle
DESCRIPTION (provided by applicant): During the previous funding period we discovered the pathogenic role of two proteins in neurological disease. By positional cloning the mouse neurological mutant pale tremor, with neurodegeneration in periph
Gene Interaction in Development and Disease
The dynamics which contribute to enzyme catalysis are best understood by defining two classes of motion – preorganization and reorganziation. Preorganization refers to how enzymes select the proper conformers needed to facilitate the catalyti
Our laboratory has been funded for ~30 years by RO1-GM26108 to investigate the mechanisms of replication control in mammalian chromosomes.  We identified the first origin of replication, which lies downstream from the DHFR gene in Chinese hamst
The presence of organelles, areas of biochemical specialization, separated from one another other by membranes, characterize eukaryotic cells. Such cellular organization necessitates elaborate mechanisms to effectively deliver the correct macr
(ARRA) Yeast genes in RNA processing & nucleus/cytosol exchange
Our research is focused on important aspects of respiratory chain assembly in mitochondria, using yeast as a model organism. We are seeking to understand the regulation of mitochondrial gene expression by proteins encoded in the nucleus that ar
TRANSLATIONAL CONTROL OF YEAST MITOCHONDRIAL GENES
This funding has purchased a state of the art rapid scan stopped flow spectrometer for use in biochemical research on the structure and function of the human enzymes Monoamine Oxidase A and Monoamine Oxidase B. These enzyme are know to be eleva
COVALENT FLAVIN COENZYME IN FLAVOENZYME CATALYSIS
The project funded by GM32335 is directed at the study of recombinational DNA repair in bacteria. Specifically, the work focuses on a better understanding of the RecA protein and its regulation. The biochemistry makes use of literally scores of
ARRA Biochemistry of Genetic Recombination/RecA Protein
To fully understand the cell cycle regulatory network as an integrated system that takes into account the 3D organization of the cell,  work on grant R01 GM032506 is  focused on how and why regulatory and structural proteins are localized to sp
Regulation of Differentiation in Caulobacter
The supplement has enable the group to retain a highly productive and experienced Research Specialist who otherwise would have her position. Additionally, the extended research proposed here is likely to add substantially to our understanding o
Mechanisms and Functions of Bimodally targeted Cytochrome P450s to Mitochondria
The correct transport of proteins must occur across the membranes of all prokaryotic and eukaryotic cells. The targeting and transport of these proteins requires several proteinaceous components that comprise the cellular transport pathway and
Redesign of Structural Regions of Alkaline Phosphatase
This application addresses the pathophysiology of sepsis and its complications potentially leading to multiple organ failure and death. This supplement aims to continue the following research: (1) Accelerate the pace of the characterization of
EPCR,TAFI as Regulators of PMN/Endothelial Interaction
This supplement request is to continue our ongoing work on the cyt bc1, by pursuing during the next two years the following specific aims, which are the natural extensions of the current work. We propose: 1  To  assess the critical role of the
BACTERIAL CYTOCHROME BC1:STRUCTURE, FUNCTION, BIOGENESIS
This administrative supplement award provides funding ($100,000) to purchase a new research microscope to facilitate and increase the rate of work on our studies of chromosome pairing in Drosophila.  The work was previously approved under NIH g
Mechanism of Meiotic Pairing in Drosophila
Multidrug resistance is an important clinical impediment in the use of chemotherapies of all types. We are using the yeast Saccharomyces cerevisiae as a model eukaryotic system that has a well described set of multidrug resistance loci called p
Genetic Analysis of Pleiotropic Drug Resistance
. Recently, 1 mammalian alpha kinase (TRPM7) has been implicated in apoptotic pathway activation in response to oxidative stress, but roles of other mammalian alpha kinases are largely unknown. Our molecular and genomic approaches in Dictyostel
CELLULAR AND BIOCHEMICAL STUDIES OF MYOSIN ASSEMBLY IN DICTYOSTELIUM
Integrin-dependent adhesion and signaling are required for cell motility, survival, and responsiveness to mechanical cues. Cells of the respiratory, cardiovascular, musculoskeletal, and urogenital systems are exposed to physical tension as part
STRUCTURE AND FUNCTION OF CELL ADHESION SITES
DNA and RNA exhibit an amazing degree of conformational polymorphism that is essential for their wide variety of biological functions, including replication and gene regulation. The importance of this polymorphism in the biological functions of
Enegetics of Oligonucleotide Conformational Heterogen
Accurate chromosome segregation is essential for the propagation of species and the viability of cells, and is driven by a complex microtubule-based structure called the spindle. Spindle organization and chromosome movement are driven by the co
Organization of the Mammalian Mitotic Spindle
This is a supplemental request to the parent grant, Biochemistry and Regulation of Cadherin Activity, that will not add to the scope or specific aims. Rather it will provide funds for the retention of a key person who was listed without salary
Biochemistry and Regulation of Cadherin Activity
Post-transcriptional regulatory mechanisms play a role in gene expression in probably all organisms. TRAP of Bacillus subtilis regulates tryptophan biosynthesis and transport by transcription attenuation and translational control mechanisms. Wh
MECHANISM OF TRP GENE REGULATION BY TRAP-RNA RECOGNITION
We propose to determine the first genome-wide estimate of mutation rates in cells that undergo meiosis.  These studies will address whether cells in meiosis sustain higher rates of mutagenesis relative to mitotic cells and whether homologous re
ROLES FOR MISMATCH REPAIR PROTEINS IN MAINTAINING GENOME STABILITY
The critically ill patient frequently develops a complex disease spectrum that may include adult respiratory distress syndrome (ARDS), systemic inflammatory response syndrome (SIRS), sepsis syndrome and/or septic shock. At present, we do not un
AMELIORATION OF SEPSIS BY MACROPHAGE ACTIVATION
We hope to increase our understanding of how the heart responds to reduced oxygen in terms of gap junction protein regulation. Specifically, our goals are to characterize changes in the gap junction protein connexin43 phosphorylation and functi
Phosphorylation of Gap Junction Proteins
Detection of folding defects in mutant CFTR by ERQC:  The purpose of this ARRA award is to develop an assay to be used to identify compounds that can be used as drugs to correct defects in CFTR that cause Cystic Fibrosis.  Funds in the award ar
Detection of folding defects in mutant CFTR by ERQC
Funding through an administrative supplement will permit us to develop new insight into a mechanism that operates upstream of a multitude of nuclear pathways.
The principal activity under this Administrative Supplement is to prepare additional TGF-? and TGF-? receptor variants, so as to increase our understanding of the similarities and differences with which the three TGF-? isoforms bind and assembl
LIGAND-RECEPTOR INTERACTIONS IN THE TGF-BETA SUPERFAMILY
In the female mammal, one of two X-chromosomes is inactivated to ensure that males and females have equal X-chromosome dosage. X-chromosome inactivation (XCI) can take place randomly or in an imprinted manner on the paternal X (XP). In the mous
Regulation of X-Chromosone Inactivation and Imprinting by Non-Coding Elements (Supplement)
Our lab is interested in how the dynamic microtubule (MT) cytoskeleton contributes to the assembly of the mitotic spindle and to chromosome segregation. This is a fundamental problem in cancer cell biology as defects in chromosome segregation a
The scope of this proposal is to study the function of mammalian lysosomal neuraminidase (NEU1) in normal cell metabolism, and the consequences of its loss in human diseases. NEU1 belongs to the ubiquitous superfamily of sialidases. Mammalian n
FUNCTIONAL/STRUCTURAL STUDIES OF MAMMALIAN NEURAMINIDASE
The purpose of this administrative supplement is to develop the genetic tools necessary to determine the mechanism by which PPS (CG6525) contributes to Sex-lethal splicing autoregulation. These studies fall under the auspices of Aim 1 of the pa
Regulation of Sex-Lethal Pre-MRNA Splicing during drosophila
The first aim of the parent project is to study the molecular mechanisms underlying the antagonistic interactions between AP2 and AG. It was already known that AP2 represses the transcription of AG in the outer two whorls, thus limiting the act
Regulation of Apetala2 flower development in Arabidopsis
Examine an RNA conformational switch in the related 3 regions of a satellite RNA (satC) of Turnip crinkle virus.  This funding provides for a Postdoc and a summer support for a minority undergraduate student and a high school biology teacher to
ROLE OF RNA STRUCTURAL SWITCHES IN THE REPLICATION OF A (+)-STRAND RNA VIRUS
THE DIFFERENITIATION OF B-LYMPHOCYTES INTO ANTIBODY-SECRETING PLASMA CELLS IS MARKED BY EXPANSION OF THE ENDOPLASMIC RETICULUM (ER). THE SITE OF ANTIBODY SYNTHESIS AND ASSEMBLY. THE PROCESS OF ER EXPANSION IS CRITICAL FOR ANTIBODY-MEDIATED IMMU
HOMEOSTASIS OF THE ER IN DIFFERENTIATING B-CELLS
S100 proteins are a group of calcium sensor proteins found only in humans and other vertebrate animals. They are members of the EF-hand family of calcium binding proteins, uniquely distinguished by their ability to be secreted into the extracel
S100 Proteins:  Structural Basis of Functional Properties
Approximately 40% of the total energy production of E. coli is consumed to synthesize the large number of ribosomal components: 3 RNAs (comprised of more than 400 nucleotides) and greater than 50 proteins. This observation and the direct correl
ASSEMBLYING AN UNDERSTANDING OF RIBOSOME BIOSYNTHESIS
X-ray crystallography using synchotron radiation is the dominant source of structural information of biological molecules and their assemblies:    The scope and specific aims of this request are:  1) complete the design of the production automo
Beamline Automation for Structure Determination
The assembly of eukaryotic DNA into chromatin structure is essential for the faithful propagation of both the genetic and epigenetic information contained in our chromosomes. In addition, chromatin structure plays an intimate role in the proper
(ARRA) Type B histone acetyltransferases and the assembly of chromatin structure
, we will follow up on our progress in understanding the nature of the stress-controlled switch from homologous to non-homologous recombination in DNA repair. Although we have not shown that RecA is down regulated by starvation, we find that a
The goal of the parent project is to achieve a greater structural and functional understanding of the macromolecular complexes formed by the 5'-untranslated region (5' - UTR) of the HIV-1 genome and the nucleocapsid (NC) domain of the Gag polyp
Structural Determinants of HIV-1 d'-UTR riboswitch and NC actuation by MS3D (note:  the above is the parent grant description - this supplement will support that grant)
A thorough description of the GO-like resting states of eukaryotic cells is essential for a complete understanding of the mechanisms controlling cell proliferation. Towards this end, we have been studying how the Ras/cAMP-dependent protein kina
(ARRA) Ras protein signaling and the control of cell growth (Administrative Supplement)
The iron-sulfur enzyme nitrogenase converts atmospheric nitrogen into ammonia, but the role of iron in the reaction is not understood. This project studies simple iron compounds in an effort to demonstrate the fundamental reactions taking place
LOW-COORDINATE SYNTHETIC MODELS FOR NITROGENASE ACTIVITY
We seek an Administrative Supplement for collaborative science to supplement ongoing NIH grant GM065997. The proposed supplement will allow us to investigate in greater detail the objectives of Aim 1 of the parent grant. In particular, we propo
REGULATION OF CULLIN-RING LIGASES BY NEDD8
Inflammation is an essential response to injury or infection as it prevents infections from becoming widespread and begins the process of healing. White blood cells (leukocytes) circulate continuously in the bloodstream but in response to a loc
EFFECT OF NEUTROPHIL PRIMING ON CHEMOTAXIS AND SIGNALING
This application requests a two-year administrative supplemental support to grant 5R01GM066233.  The long term goal of the parent grant is to elucidate the molecular and cellular mechanisms of organic cation transport at the CNS barriers.  The
Methylamine dehydrogenase (MADH), a metabolic enzyme found in methylotrophic/autotrophic bacteria, contains a quinone cofactor, tryptophan tryptophylquinone (TTQ), derived from the post-translational modification of two Trp residues in the prot
BIOSYNTHESIS OF AMINO ACID DERIVED QUINONE COFACTORS
Understanding regulatory mechanisms that maintain pluripotent embryonic cells and control differentiation has fundamental relevance to scientific areas central to human health and disease, including stem cell, developmental, and cancer biology.
This is a supplement to the existing award # 2 R01 GM067104.        All viruses must take over the host's protein synthesis (translation) machinery. Cellular mRNAs require a 5' cap and poly(A) tail to recruit the ribosome and initiate translati
Control of Cap-Independent Translation by a Viral 3' UTR
Our specific aims are to 1) Investigate the mechanisms through which  viral proteins disrupt the mRNA export machinery; 2) To study regulation of mRNA export by antagonists of viral-mediated mRNA export block; and 3) To determine the role of mR
Regulation of mRNA Export by Viral Proteins - ARRA Stimulus Admin Suppl
Cells and tissues establish and maintain their unique architectures in large part through the tight regulation of protein and membrane transport. One key aspect of this process is endocytic recycling, the selective return of internalized macrom
Endocytosis and Recycling in C.elegans and Mammals
The ability of B lymphocytes to capture, process and present antigens to T cells is requisite for normal humoral immune responses and contributes to the pathogenesis of both B and T cell mediated autoimmune diseases. B lymphocytes preferentiall
B CELL RECEPTOR REGULATION OF ANTIGEN PROCESSING
The purpose of our ARRA supplement request was to obtain a portion of the funds needed to procure a state of the art laser scanning confocal microscope, an instrument essential for our work on asymmetric divisions. Asymmetric divisions occur wh
MOLECULAR AND GENETIC ANALYSIS OF SANPODO
We propose to analyze crystal structures of non-erythroid spectrin alpha II, to design and prepare mutants that will affect the spectrin II tetramerization region and the alpha and beta spectrin association, and to grow crystals of the alpha be
National Aeronautics and Space Administration
Recovery - Mobile Launcher Element (MLE) Electrical Design (CLIN 009)  The Mobile Launcher (ML) is a large platform with a tower used to transport, service, and launch the next generation launch vehicle and spacecraft (Ares I and Orion). This e
This effort develops the Next Generation Airborne Visible/Infrared Imaging Spectrometer (AVIRISng) to address the science measurement requirements to support both the NASA HyspIRI Decadal Survey Mission and the Research and Analysis Program of
*The slit assembly was installed and aligned
CEDAR GROVE IMPROVEMENT ASSOCIATION, THE
Rural Development funds will be used to complete the interior construction of the Cedar Grove Community Center.
HOUSING AUTHORITY OF THE CITY OF ROCKY MOUNT
Installation of Hybrid Furnace / 15 Seer Heat pump system in all units in 2 Communities
ARRA Capital Fund Public Housing Modernization AMP2
Installation of HVAC (heating and air conditioning) Systems. The Morganton Housing Authority is implementing the following activities using Capital Fund Recovery Act funding; 150 units of the Providence Place (NC049000002)public housing develop
Public Housing Capital Fund Competitive ( Recovery Act Funded )
HOUSING AUTHORITY OF THE CITY OF HIGH POINT
The Housing Authority of the City of High Point (HPHA) will complete 4 major projects utilizing the 2009 ARRA CFRG funding. These projects will include HVAC, sidewalk, driveway replacement, and storm drain repairs, etc. This money will also be
HOUSING AUTHORITY OF THE CITY OF WILMINGTON, NC
The Authority is currently revising its ARRA budget to redirect unspent funds to the expansion of a rehab project at Creekwood South.  Originally a 27-unit project, we have completed the work to fully renovate all 18 buildings already engaged a
ARRA Capital Fund Formula Recovery Grant
HOUSING AUTHORITY OF THE CITY OF CHARLOTTE, N.C.
This formula grant will be used on a multitude of projects designed to modernize and improve public housing units owned and managed by the Charlotte Housing Authority. Specific projects include improving HVAC, roofing, security, community rooms
HOUSING AUTHORITY OF THE CITY OF ASHEVILLE
Recovery Act funds will be used to carry out Phase 4 of the comprehensive modernization at the PHA's Klondyke Homes community.  Work includes asbestos tile abatement, new flooring, framing, cabinets, electrical, plumbing, energy efficient heati
The Redevelopment Commission of the Town of Tarboro is implementing the following activities using Capital Fund Recovery Act funding: 34 units of the PINEHURST HOMES (NC017000001)public housing development are being rehabilitated.
Replacement of kitchen cabinets in 97 units of public housing
modernization in bathrooms of 140 public housing units
American Recovery and Reinvestment Act Capital Fund Formula Grants
Heating/air conditioning, Interior Door Replacement, Vinyl siding installation/replacement
CONDUCT MODERNIZATION ACTIVITIES AT VARIOUS PUBLIC HOUSING DEVELOPMENTS AS FUNDING CAN BE EXPECTED TO PROVIDE NEEDED IMPROVEMENTS TO THE PHYSICAL STRUCTURES OF THE DWELLING UNITS.
Landscaping upgrades for erosion control.
Public Housing Capital Funds Recovery Act
The North Davidson Street Facility was constructed in 1980 and 1981 and includes a two-story (plus basement) administration/operations building (14,268 square feet), a three-level (including mezzanine) maintenance building (62,116 square feet),
RESEARCH TRIANGLE REGIONAL PUBLIC TRANSPORTATION AUTHORITY
Invest in public transportation by purchasing new heavy-duty transit buses, new paratransit vans, a Real-Time Passenger Arrival System, repaving the Bus Operations and Maintenance Facility parking lot, and various transit enhancements throughou
Purchase of five replacement buses, three replacement paratransit vans, a Real-Time Passenger Arrival System, repaving of the Bus Operations and Maintenance Facility, and transit enhancements for Triangle Transit.
Invest in public transportation by supporting a portion of the construction activities (30.2%) for a new Transit Maintenance and Operations Facility and Administrative Offices for the Greensboro Transit Authority. This 'LEED Gold Designed' faci
Purchase of new buses to expand existing urban transit routes; purchase of equipment to upgrade vehicles and maintenance operations; and facility improvements to operational facilities utilized by riders, including transfer stations and shelter
2009 Transit Capital Assistance Grants - This grant applies the 2009 ARRA Formula allocation of $700,000 an AVL/GPS system for complete tracking of 12 buses. This includes hardware, software, and training for a total of $700,000. This grant app
SNOW HILL RURAL FIRE DEPARTMENT, INCORPORATED
Purchase and renovation of building for use as fire station
Snow Hill Rural Fire Department / Fire Station
Public Housing Capital Fund Stimulus (Formula) Recovery Act Funds
Conduct modernization of Public housing family units: replacement of siding, adding additional insulation; replacement of damaged windows with energy efficient windows.
American Recovery and Reinvestment Act (ARRA) Formula Grant.
Removal of the old streets and parking lots, after the Demolition of Pleasantview Homes Development was completed under a separate contract (a former family development).  In addition, major renovation of Crown Tower, which had been delayed due
Engineering and construction of Fire Sprinkler and Life Safety Improvements at Multiple Towers
Conduct Modernization at the Clay Center Housing Authority.  This funding will result in providing employment for construction
American Recovery and Reinvestment Act - Capital Fund Stimulas Grant; purpose is to assist the PHA in caring out capital and management activities at Public Housing Developments.
replace windows and doors with energy efficient ones, upgrade walkways to ADA compliant with no steps on landings
Public Housing Capital Fund Stimulus (Formula) Recovery Act Funding
storm door replacements-some A/C replacements-some cupboards- some flooring & bathroom fixtures
Conduct modernization of units by installing energy efficient heating systems, bath exhaust fans and lighting. Also conducting site improvement by replacing exterior cement steps and hand railing.
ARRA awards for concrete, door replacement, renovating apartments
HOUSING AUTHORITY OF VILLAGE OF SUTHERLAND
Comprehensive modernization of elderly units;replacement of windows in all units with energy efficient windows and painting the exterior siding of all buildings; replacement of refrigerators with Energy Star compliant refrigerators.
Modernization:  Conduct one elevator replacement and one elevator renovation at public housing development.   Provide or retain employment for architects, engineers, contractors, subcontractors
Gosling Meadows:  Replace streets, curbs, sidewalks, parking areas Margeson Apartments: Replace trash compactors Feaster Apartments; Replace trash compactors and repoint exterior brick
LACONIA HOUSING & REDEVELOPMENT AUTHORITY
Modernization of Heating and A/C System with energy efficient components. Security System at elderly complex. Repair of Ramps, Walks & Retaining Walls.
ARRA Capital Fund Grant. Replacement of roofing, siding, and repair of exterior storage sheds on 29 public housing units at a family complex
Two projects, both completed. 1: installation of new roof on 96-unit apartment building (2009). 2: repaving parking areas/reconstruction of sidewalks. These projects provided employment to architects, engineers, construction workers, and produc
Public housing modernization activities including reconstruction/expansion of parking lot at elderly site and kitchen renovations at another elderly site.  Both projects will also enhance accessibility for persons with disabilities.
High levels of iron and maganese causing aesthetic and mechanical issues in the water treatment program. The City is a low income area with high levels of unemployment therefore grant loans were sought for this project. We'll be using this mone
Water System Improvement Project - Water Only Combo (loan/grant)
Farmington WWTF Upgrade, Waste Only Combo
Rehabilitation of Waste Water Treatment Facility
The response of macrophages to infectious microorganisms is enhanced by interferon (IFN) gamma through gene expression modulation, which results in an increased ability to respond to infection. We have shown that the local production of IFNgamm
Control of Macrophage Responses to Borrelia Burgdorferi by IFNg
In our proposed research we will develop a novel approach for magnetically-driven organization of ordered cellular structures without using microfabricated substrates, potentially harmful electrical fields, or the physical attachment to or upta
Recognition and Presentation of Alpha Helices Using Nanoparticle Receptors-NIGM
These supplemental funds will permit one African American female to be hired during the academic year to undertake research of one of the original aims of the parent research grant proposal. These funds further permit her to be employed over th
Evolution of Stress-Induced Bacterial Toxins
Hsp70 chaperones occur in all organisms and essentially all cellular compartments. Among their wide array of essential cellular functions, they facilitate folding of newly synthesized proteins; protect cells from damage such as aggregation that
Allosteric Mechanisms of HSP70 Molecular Chaperones
The focus of the proposed research is on structural plasticity and large-scale dynamics as determinants of protein function. Detailed and highly specific characterization of functionally important transient non-native protein states will rely o
Investigation of Protein Dynamics by Mass Spectrometry.
BOROUGH BUENA MUNICIPAL UTILITIES AUTHORITY
Borough of Buena MUA's Effluent Disposal Facility 35-005-0202415479 (PII)
Borough of Buena MUA's Effluent Disposal Facility
To install new infrastructure in various areas of the Borough of Penns Grove to replace aging and/or deteriorating sanitary sewer collections systems.
Penns Grove Sewerage Authority Rehabilitation of Sanitary Sewer System
To install new infrastructure in various areas of the Borough of Penns Grove to replace aging and/or deteriorating sanitary sewer collection systems.
City of Wildwood Sewer Replacement Phase 3A
HOUSING AUTHORITY OF THE CITY OF JERSEY CITY INC
The JCHA will implement energy efficient and 'green' work items to improve Holland Gardens.
Category 1 (Elderly and Persons with Disabilities)Capital Fund Recovery Competition. We will be constructing 5,000 square foot new facility space for an Assisted Living Program that houses approximately 30 staff of Nurses, Certified Nursing Ass
Category 1 (Elderly and Persons with Disabilities)Capital Fund Recovery Competition.
On February 17,2009, President Obama signed into law the American Recovery and Reinvestment Act (ARRA). The ARRA created an economic stimulus package that provides approx $4B allocated for housing projects.  NHA share of the funding for Capital
ARRA Capital Improvements Authority Wide
Stimulus Grant utilized to remove & replace roof shingles at all senior citizen complexes (120 units); remove & replace domestic hot water tank & related piping; replace existing interior/exterior lighting with energy efficient lighting
VARIOUS CAPITAL PROJECTS WITH AN EMPHASIS ON ENERGY EFFICIENCY AND SHOVEL READY PROJECTS
HOUSING AUTHORITY OF THE CITY OF BURLINGTON
Public Housing Capital Fund Stimulus (Formula) Recivery Act Funded
Housing Authority of the City of Burlington
Funds were to create jobs and employment in the community.
Interior Renovations at West End Gardens
To provide funds for the capital and management activities of Public Housing Agencies. The fund will be used for capital and management activities, including modernization. Public Housing Agencies shall prioritize capital projects that are alr
2009 American Recovery & Reinvestment Act, HUD Capital Fund Program Stimulus Grant
The Housing Authority will conduct modernization activities at Granville Towers, a low income pubic housing development for the elderly and disabled. This funding will generate employment for architects and engineers, construction workers and b
Victims Compensation will provide funding for victim programs that serve victims and survivors of domestic violence, sexual assault, child abuse, homicide and other Federal and state crimes. Additionally, funds will be used to provide compensat
To provide direct services to crime victims in support of the Recovery Act objectives to preserve and create jobs and promote economic recovery.  Performance measures include:  Number of jobs retained due to Recovery Act funding and essential s
Recovery Act - OVC FY09 VOCA Victim Compensation Formula Grant Program
The South Carolina Department Public Safety, acting as the State Administrative Agency, administers and manages the Victims of Crime Act funds under the ARRA.  The purpose of the program in South Carolina is to expand or enhance direct services
This grant award provides funds from the American Recovery and Reinvestment Act of 2009 to enhance crime victim services in North Carolina.  The Recovery Act-OVC FY09 Victims of Crime Act (VOCA) Victim Assistance Formula Grant Program funds are
Recovery Act-OVCFY09 VOCA Victim Assistance Formula Grant Program
CRIMINAL JUSTICE SERVICES, VIRGINIA DEPARTMENT OF
Recovery Act – OVC FY2009 Victims of Crime Act (VOCA) Victim Assistance Formula Grant Program funds are competitively awarded by Virginia to local community based programs providing direct services to crime victims. It is anticipated that ann
Recovery Act – OVC FY2009 Victims of Crime Act (VOCA) Victim Assistance Formula Grant Program
The state of Michigan is using the State Crime Victim Assistance ARRA funds awarded to the Michigan Department of Community Health to support three community-based organizations which serve crime victims for the project period 10/1/2009-9/30/20
2009-SG-B9-0120 Recovery Act -  VOCA Victim Assistance formula grant to the Michigan Crime Victim Services Commission CFDA# 16.801
The Recovery Act - OVC FY 09 Victims of Crime Act (VOCA) Victim Assistance Formula Grant Program funds are competitively awarded by the State to local community-based organizations that provide direct services to crime victims.
Recovery Act OVC FY 2009 VOCA Victim Assistance Formula Grant Program
The final recommendations for the VOCA ARRA grants were approved on November 20th, 2009.  Grant contingencies were due on December 24th, 2009.  The grant project period started on January 1st, 2010.  These funds will provide and expand direct s
OVC VOCA Victim Assistance Formula Grant Program
Recovery Act-VOCA Victim Assistance formula grant to support the provision of services to victims of crime throughout the State of Colorado.  Services are defined as those efforts that (1) respond to the emotional and physical needs of victims
Recovery Act - OVC FY09 VOCA Victims Assistance Formula Grant Program
This project aims to help reduce youth risk of victimization through technology use (i.e., Internet, text messaging, webcams). It will survey a nationally representative sample of 1,500 youth to: 1) continue to track existing trends in the numb
National Study of Internet and Technology-Facilitated Risks to Youth
The Internet Crimes Against Children (ICAC) Task Force Program seeks to maintain and expand state and regional ICAC task forces to address technology-facilitated child exploitation.  These task forces work collaboratively as a national network
The program will go to funding the following items:                                                                                                                                                                                      -
Recovery Act ICAC Task Force Forensic / Investigative / Training Support
The funds provided by the Recovery Act will allow the Los Angeles Regional Internet Crimes Against Children Task Force to quickly respond, investigate and prosecute incidents involving the exploitation of juveniles through the use of the Intern
The New Mexico Attorney General's Office (NMAGO), as the grantee for the New NMICAC, plans to use the Recovery Act grant monies to address personnel needs that directly supports the protection of children from exploitation via technology.  The
OJJDP FY 09 Recovery Act Internet Crimes Against Children Task Force Program Grant
The core focus of this award is to protect children from computer/technology facilitated sexual exploitation.  The grant funds are utilized to employ, train and equip personnel dedicated to this mission, and to increase the effectiveness of the
The North Dakota ICAC task force will enable local, state and federal law enforcement to continue their efforts to protect children from becoming victims, educate children about the internet, and apprehend and prosecute those responsible for in
Fund the Montana Internet Crimes Against Children Task Force Program Coordinator's position and to provide overtime funding for forensic examiners.
In an effort to combat child exploitation and sexual predators on the internet while preserving and creating jobs, this project is designed to offer support to all West Virginia law enforcement agencies investigating computer facilitated child
OJJDP FY 2009 Recovery Act Internet Crimes Against Children Task Force Grant Program
The MO ICAC program serves as a resource to criminal justice agencies and citizens of Missouri by offering investigative, forensic and prevention materials through its Affiliates and partner agencies.  MO ICAC provides law enforcement with the
In accordance with the grant announcement, the following goals, objectives and deliverables are identified:                                                                                      Goal 1: The Broward Sheriff?s Office with the Browa
Broward County/South Florida ICAC Task Force
The Internet Crimes Against Children (ICAC) Task Force seeks to maintain and expand State and regional ICAC task forces to address technology facilitated child exploitation.
This project will address law enforcement technology requirements and priorities in the areas of officer safety, public safety, decision making, and information sharing. In consideration of the goals, objectives, and intended impact of the Reco
SRFERS: State Regional & Federal Enterprise Retrieval System III
NATIONAL LAW ENFORCEMENT TELECOMMUNICATIONS SYSTEMS INC
E-Port -- Enhanced Portal for Image Exchange and Increased Functionality over NLETS
Under Category I: Combating Criminal Narcotics Activity, Santa Cruz County, in conjunction with the Santa Cruz County Attorney's Office (SCCAO),will use its award to combat criminal narcotics activity through increased job creation, improve age
Santa Cruz County Attorney's Office Intelligence-Led Policing Program
The San Mateo County Sheriff's Office (Prime Recipient), applied on behalf of and as the fiduciary of the Northern California High Intensity Drug Trafficking Area (NCHIDTA) and the Northern California Regional Intelligence Center (NCRIC) for th
Enhancing Intelligence-Led Policing (ILP) Capabilities in the Area of Responsibility of the NCHIDTA and Northern California Regional Intelligence Center through Implementation of a Regional ILP
Award Title: FY09 Recovery Act Combating Criminal Narcotics Activity Stemming from the Southern Border of the United States: Combating Criminal Narcotics Activity along the Southern Border. The purpose of the award is to identify and apprehend
San Diego County, United States/Mexico Border Criminal Interdiction Strike Team
The State and Local Law Enforcement Assistance Program:  Combating Criminal Narcotics Activity Stemming from the Southern border of the United States  is designed to provide resources for hiring, retention, assistance, and equipment to local la
Webb County Sheriff's Office Enhancing the Webb County Jail
FY 2009 Recovery Act Assistance Grant Program
The Alaska Department of Public Safety will use the funds to hire five new State Troopers, one new administrative assistant, and one new prosecuting attorney. These seven new positions are being added to make the following desired changes to Al
Recovery Act - Edward Byrne Memorial Justice Assistance Grant (JAG) Program is expected to fund an estimated 40 Full-Time Equivalent positions (FTEs). Over 2,200 adult and juvenile offenders will be provided a variety of re-entry/recidivism red
Recovery Act - Edward Byrne Memorial Justice Assistance Grant (JAG) Program, Awards to States and Territories
Missouri Department of Public Safety will use its JAG award to implement progressive community, multi-jurisdictional, judicial, correctional, analytical, and informational-based response strategies that enhance public safety and reduce violcent
The State of Wisconsin JAG ARRA award provides a unique opportunity to address system wide improvements in criminal justice. There is a growing consensus that the country must find solutions to growing prison costs; find the right response to o
Support programs which pursue violent and predatory criminals.  Support efforts with law enforcement, prosecution, and probation to combat and disrupt illegal drug use, violent crime, illegal gun and gang activity and test drug users.  Support
Recovery Act - Edward Byrne Memorial Justice Assistance Grant (JAG) Formula Program
The goal of this project is to develop Web-based training to help sexual assault response professionals handle cases involving drugs and alcohol. RTI will develop and deliver five Web-based training modules to further educate sexual assault nur
Web-Based Training for Forensic Examiner Practitioners and Ancillary Professionals for Victims of Drug-Facilitated Sexual Assault
FORGE, Inc., proposes a project designed to begin remedying the problem of transgender sexual assault survivors who refuse mainstream sexual assault services, by developing and providing training, technical assistance, and demonstration sites t
Transgender Victims of Sexual Violence:  Training, Technical Assistance, and Demonstration Projects
Survivor-Informed Training and Technical Assistance
Survivor Informed Training and Technical Assistance Project
This ARRA project is being implemented in order for the FWS and TNC to work together for the purpose of implementing prescribed burns on private lands targeting grassland habitat in the Edwards Plateau and the Trans-Pecos Ecoregions of Texas.
Improved, repaired, and modernized real property and improved energy efficiency in facilities.  Projects included exterior lighting upgrades at various Armories/Field Maintenance Shops in Fillmore, Logan, Ogden, Richfield, St George and undergr
National Guard Military Operations and Maintenance Projects
I-94 - From E Dawson Interchange To Crystal Springs
I-94 - From W Eckelson E To E ND 1-OAKES
SOUTHEAST KENTUCKY ECONOMIC DEVELOPMENT CORPORATION INC
Jeff Sheppard, LLC Revolving Loan Project This project supports a Revolving Loan Fund. As such, the FTE reflected here represent only those for the administration of the project. Because RLFs generate multiplier effects in the community as they
Jeff Sheppard Apparel, LLC Revolving Loan Project
Tyrosine kinases are important regulators of growth, differentiation, and apoptosis in eukaryotic cells. Inappropriate activation of tyrosine kinases often occurs in human cancers. The goal of this project is to understand the contributions of
ARRA: Substrate Specificity of Nonreceptor Tyrosine Kinases
Enhancement of Border Communications and Interoperability Project.
INDIAN STREET BRIDGE FROM W. OF MAPP ROAD TO E. OF KANNER HIGHWAY
SR-811/DIXIE HWY FROM BROW/PLM BCH CO LINE TO SW 18 ST/BOCA
Install Pedestrian Lighting MD 124 Airpark Road to Rosewood Manor Lane
Geometric Improvements at Klees Mill Road (Left Turn Lanes)
SR 5/OVRSEAS HRT.TRL LOWER SUGARLOAF HISTORIC BRIDGE AT MM 15.5
MAIN STREET STREETSCAPE ENHANCEMENT PROJECT, V/ DOLGEVILLE
The project will replace and repair the existing sanitary sewer lines throughout the City of Bricelyn so that the Minnesota Pollution Control Agency standards are met.  Rural Development is providing loan and grant funds.
The project will replace and repair the existing sanitary sewer lines throughout the City of Bricelyn so that the Minnesota Pollution Control Agency standards are met.
BASIC INSTALL ASSISTANCE DIGITAL TV CONVERTER BOX
Consumer Electronics Repair and Maintenance
Safety and Resurfacing from Structure 1007901 Bennett Creek to Structure 1007801 MD 80
Valley City - Wintershow Road from 4th Avenue SW to 5th Avenue SE
SAN JOAQUIN VALLEY UNIFIED AIR POLLUTION CONTROL DISTRICT
ARRA - NATIONAL CLEAN DIESEL PROGRAM This cooperative agreement provides funding to San Joaquin Valley Unified Air Pollution Control District under the American Recovery & Reinvestment Act of 2009. This project will repower approximately 30 agr
ARRA - NATIONAL CLEAN DIESEL PROGRAM - Agricultural Off-Road Vehicles
The Alabama Clean Fuels Coalition, Inc (ACFC) was awarded a National Clean Diesel Funding Assistance program Grant to fund a Truck Stop Electrification project targeting truck fleets in Baldwin and Montgomery Counties in Alabama. The general pu
National Clean Diesel Funding Assistance Program (B)
Cascade Sierra Solutions was awarded a National Clean Diesel Funding Assistance Program Grant to fund a retrofit program targeting fleets in Idaho, Oregon, and Washington. The general purpose of the grant is to reduce diesel emissions and impro
The Port Authority of NY & NJ was awarded a National Clean Diesel Funding Assistance Program Grant to fund a Regional Truck Replacement Program targeting pre-1994 drayage trucks that regularly service the Port Authority's marine terminals with
CALSTART was awarded a National Clean Diesel Funding Assistance Program Grant to fund a replacement program targeting delivery trucks in NY and NJ.  The general purpose of the grant is to reduce diesel emissions and improve air quality.
CALSTART Consortium Hybrid Truck Emission Reduction Program
The City of Lincoln was awarded a National Clean Diesel Funding Assistance Program Grant to fund a retrofit program targeting on-road vehicles, non-road vehicles, locomotive switch engines, and generators in the City of Lincoln and Lancaster Co
Lincoln-Lancaster National Clean Diesel Grant Program
Roofing Replacement and Rehabilitation at 1403, 1405 and 1407 Teresa Drive, Fort Lee, New Jersey
Replace ceiling tiles, replace lighting, install exterior camera system, front and rear entrance door systems.
Conduct modernization activities at a Public Housing development.  This funding can be expected to result in providing employment for architects and engineers, construction workers, technicians and product manufacturers.  In addition, this fund
To provide training for transit systems through the delivery of 34 Project Management for Transit Professionals and 6 Management of Transit Construction Projects sessions.
FTA project and construction management training
All Other Support Activities for Transportation
CLOVIS HOUSING & REDEVELOPMENT AGENCY INC
America Recovery and Reinvestment Act Formula Grant
Clovis Housing & Redevelopment Agency, Inc.
HOUSING AUTHORITY OF THE CITY OF TRUTH OR CONSEQUENCES
Conduct modernization activities at Public Housing development.  Replace existing outdated heating systems with energy efficient HVAC systems and programmable thermostats and replace duct work as necessary.  Affects 30 family housing units, on-
Re roof 35 dwelling units in one development.
Mainframe tape equipment including Sun StorageTek T10000B Recovery Tape Drives and related Tape Media. Installation of Equipment
The contractor shall provide Cisco equipment
Task Order 15: Caulk Leaking Precast Exposed Aggregate Facing Panels
Blanket Purchase Agreement NNJ09JE25T (Call 13) support continues to procure administrative support services for the Office of Procurement in support of the placement and administration of construction contracts funded by the Recovery Act.  Adm
The purpose of this cooperative program is to conduct activities related to the NASA ARRA supported wildfire response and management project.  NASA and the U.S. Forest Service developed the Wildfire-Collaborative Decision Environment (W-CDE) to
Recovery Act - Integration of NASA Earth Science Information into a Wildfire Collaborative Decision Environment (W-CDE)
Development and delivery of Time Delayed Integration APD/CCD sensor chips
The Passamaqyoddy Tribe at Pleasant Point receives its drinking water from the Passamaquoddy Water District (PWD), with the source from Boyden's Lake in Perry, Maine.  The Water system is in non-compliance for primary MCL standards, disinfectio
Sanitation Facilities for Water Source Study, Passamaquoddy Tribe at Pleasant Point
Installation of residential water meters and leak detection equipment
EPA provided HIS $349,000.00 of Drinking Water Initiative Grants Tribal Set Aside funds through an Interagency Agreement (IAG) DW-75-95766001-0 for this project. Project Scope: Expand the existing surface water water treatment plant with a 30x4
IHS Water Loss Monitoring Sanitation Facilities
The project summary defines a project to service 214 homes and 18 buldings with community sanitation facilities.  The total cost of this project is estimated to be $175,419.00.  This project will provide $175,419.00 if EpA drinking water Instra
Alabama-Coushatta Sanitations Facilities for Water Loss Monitoring
Nonlinearities in the Arctic Climate System during the Holocene
This CAREER award supports an integrated theoretical research and education program to study the controlled formation of complex, three-dimensional structures. Analytical and numerical methods will be used for two related research topics. The f
Geometry of Directed Folding and Soft Packing
The objective of this work is to study biomolecular interactions individually, even when they are transient and irreversible. To this end, a droplet-based method for molecular confinement and mixing will be adapted to make possible the use of s
Transient and Irreversible RNA-Protein Interactions Studied one-At-A-Time
Neighborhood Stabilazation Program (NSP 1)formula grant  The City of Morristown planed to utilize the NSP I funds allocated for Hamblen County ($376,022) to purchase and clear vacant and abandoned properties located in areas of highest need wit
Community Facilities, grant only - Purchase of a refrigerated truck to be used for the pick up and delivery of commodities.
CAPITAL FUND RECOVERY GRANT - conduct modernization activities at various sites. improve accessibility patios
Public Housing Capital Fund Recovery Grant
Ny-00-02 Grant in combination with NY-97-01 Loan amd NY-00-08 Grant Community Facilities Combo (loan/grant)  The Village was awarded a combination of one loan ($2,795,000) and two grants ($100,000 each) from USDA/Rural Development which will be
Village of Waverly-Purchase/Renovate Village Hall
BETTER COMMUNITY HOUSING DEVELOPMENT FUND INC
WPHA will make significant 'Green' improvements to the major systems at the 86 DeKalb location.  Improvements will include mechanical system, water system and roof improvements.
Conduct modernization activities at various Public Housing sites. Projects include bathroom modifications, kitchen improvements, site work boiler improvements, and storm door replacement at the Day complex.  At Quinn bathroom and roof repairs.
Building an addition to an existing structure at Carlisle Hills Apartments.  This will provide employment for architects, engineers, construction workers, electricians, plumbers, HVAC specialists, and product manufacturers.
Conduct modernization activities at various public housing developments. this funding can be expected to result in providing modernization improvements to the Authority.
Public Housing Capital Fund Stimulus ( Formula ) Recovery Act Funded
Security Improvements, Architect and engineering Fees, Site Lighting, Security Cameras, Kitchen Caqbinets, Bathroom Exhausts, Trashroom Equipment, Sprinkler System
Massena Housing Authority's ARRA Capital Fund Grant is being used for administration, rehabilitation and new construction at Meadowview and Victory Apartments
Massena Housing Authority ARRA Capital Fund Grant
GHA 2009 ARRA Capital Fund Formula Program
The award is a Public Housing Capital Fund Stimulus (Formula) Recovery Act Fund Grant for the  purpose of making needed improvements and upgrades to our public housing projects.  These physical improvements will sustain local contractor jobs an
Modernization activities to include repalacement of boilers and furnaces with 95% efficient units and upgrades to Community Bldg. lavatories
Public Housing Capital Fund Stimulus (Formula) Recovery Act  Funded
75 Units of the Great Neck Senior Citizen Housing (NY144000001) public housing development was rehabilitated.
MUNICIPAL HOUSING AUTHORITY FOR THE CITY OF YONKERS INC
Conduct modernization activities at various Public Housing developments.  This funding can be expected to result in providing employment for architects and engineers, construction workers and product manufacturers.  In addition to this funding
Gateway Gardens Kitchen and Bath Upgrade
Public Housing Capital Fund Stimulus (Formula): This award is being used for modernization of the dwellings. Stimulus funds will be used for apartment renovations and roofing.
Section 8 Housing for individuals with developmental disabilities.
Invest in public transportation with the following projects Metro-North Railroad: Tarrytown Platform And Canopies Rehabilitation, Poughkeepsie Station Building Windows & Doors, Grand Central Terminal Elevators; New York City Transit: Vent Plant
Metropolitan Transportation Authority ARRA §5309 Metro-North/New York City Transit  Fixed Guideway Mod
TOA code 538 water only loan.  Rural Development funds will be used to construct a new well, replace water main lines, and address water quality issues.
Invest in Public Transportation by procuring three (3) 35 FT hybrid-electric buses, two (2) 40 FT hybrid-electric buses for Transport of Rockland (TOR), the County's inter-county bus system.  We will also procure three (3) 45 FT hybrid-electric
City-wide environmental assessment of properties in the City of Rock Island.
This is a Brownfields Cooperative Agreement (CA) for the City of  Battle Creek, MI to evaluate sites believed to be contaminated with hazardous substatnces. The CA will enable the City of Battle Creek to continue its ongoing efforts to redevelo
City of Battle Creek Stimulus Brownfields Assesment Hazardous
Stimulus funds provided to conduct community-wide assessments at potential brownfield sites contaminated with petroleum substances.  Conduct prioritization, then Phase I & Phase II assessments at selected sites.  Funds used also for public outr
Award Title:  Brownfields Assessment and Cleanup - ARRA The overall purpose of this award is to clean up contaminated properties for redevelopment.  The primary purpose is to work on projects that are 'shovel ready' and will maximize economic b
Brownfields Assessment and Clean-up Grants
American Recovery and Reinvestment Act funds will be used by the City of Talladega to conduct community-wide assessments at brownfield sites which are potentially contaminated with petroleum and hazardous substances.  The City of Talladega may
American Recovery and Reinvestment Act funds will be used by the City of Georgetown, Kentucky, for the clean up of hazardous substance contaminants at the Former Empire Pencil Factory site. During the life of the project, the City of Georgetown
Hazardous Substance Cleanup of Former Empire Pencil Property
Stimulus regional petroleum assessment grant.
Windham Regional Commission Hazardous Substances Assessment Program
Performing environmental assessment activities at eligible Brownfields properties contaminated with petroleum located at the target community.
To perform cleanup of hazardous substances at Lot 75 located in the Town of Howland, ME.
hazardous substances cleanup at Lot 75 located in the Town of Howland, ME.
To perform cleanup of hazardous substances at Lot 37 located in the Town of Howland, ME.
hazardous substances cleanup at Lot 37 located in the Town of Howland, ME.
Create a Revolving Loan Fund Program to facilitate hazardous substances cleanup loans and grants to eligible entities.
UPPER EXPLORERLAND REGIONAL PLANNING COMMISSION
The American Recovery and Reinvestment Act (ARRA) Funding, Brownsfields Petroleum Assessment.  This agreement provides Amercian Recovery and Reinvestment Act funding to Upper Explorerland Regional Planning Commission to be used to conduct commu
American Recovery and Reinvestment Act Funding, Brownfields Petroleum Assessment
STATE ENVIRONMENTAL IMPROVEMENT AND ENERGY RESOURCES AUTHORITY
ARRA EIERA Brownfields RLF: This award provides American Recovery and Reinvestment Act funds to the Missouri Environmental Improvement and Energy Resources Authority to utilize funding to provide a Brownfields Revolving Loan Fund for State of M
Clean Up and Disposal of Environmental Contaminates for the Old Tekakwitha Orphanage/Boarding School Buildings Complex
ENVIRONMENTAL MANAGEMENT, THE INDIANA DEPARTMENT OF
The Indiana Department of Environmental Management was awarded a State Clean Diesel Program Grant to fund exhaust retrofit technologies, idle reduction technologies, diesel engine upgrades, repowers, diesel vehicle replacements, aerodynamic tec
The Michigan Department of Environmental Quality was awarded a State Clean Diesel Program Grant to fund a retrofit/replacement/repower projects for programs targeting school buses, construction equipment, long haul or heavy-duty trucks, medium-
American Recovery and Reinvestment Act - Clean Diesel- Michigan Department of Environmental Quality
The New York State Department of Environmental Conservation was awarded a State Clean Diesel Program Grant to fund a retrofit project targeting diesel buses in Albany, Syracuse, Rochester and Buffalo, NY.  The general purpose of the grant is to
The State of Delaware was awarded a State Clean Diesel Funding Assistance Program Grant to fund a retrofit/replacement program targeting school buses and sanitation vehicles, a diesel generator at State Park and a new truck stop electrification
The State of Wyoming was awarded a State Clean Diesel Program Grant to fund a retrofit and replacement project targeting school buses in Wyoming. The general purpose of the grant is to reduce diesel emissions and improve air quality. Units of m
ARRA Diesel State Grant Program - WY DEQ
Drinking Water State Revolving Fund-ARRA To provide low-interest loans and principal forgiveness to local gov't for drinking water infrastructure projects.
This grant will provide funding for an island wide leak detection survey and water metering of Guam Waterworks Authority's (GWA) facilities.  The leak detection survey and water metering of GWA facilities will result in reduction of unaccounted
Leak Detection and Metering GWA's Facilities project   ARRA-Drinking Water InfrastructureTerritorial Set-Aside Program
The Commonwealth Utilities Corporation (CUC) has about 38 wells that feed directly into the system.  These wells wastes energy unnecessarily, have frequent motor/pump replacements, and most importantly, has the highest detection of bacteria whe
ARRA-DRINKING WATER INFRASTRUCTURE TERRITORIAL SET-ASIDE PROGRAM
This agreement provides funding under the American Recovery and Reinvestment Act (ARRA) of 2009 to the state of North Carolina to capitalize its revolving loan fund for financing the construction of drinking water treatment facilities and assoc
Capitalization Grant for Drinking Water State Revolving Fund. A total of six projects will be funded and recipients will receive a combined total of $9,750,000 in principal forgiveness.  Three projects are identified for the green project reser
WA State Funds for the DWSRF program - ARRA.  This agreement provides funding under the American Recovery and Reinvestment Act of 2009 to the state of Washington to capitalize its revolving loan fund for the financing for the construction of dr
Award Description: This agreement provides funding under the ARRA of 2009 to the State of Massachusetts to further the public health protection objectives of the SDWA through the financing of water system infrastructure improvements, especially
To capitalize the State Revolving Fund for financing the construction of drinking water facilities and green infrastructure projects (DWSRF) which will preserve and create jobs and promote economic recovery through infrastructure investment pro
Funds will be used to Improve drinking water infrastructure of 23 systems.  Outcomes will consist of new or rehablititated infrastructure and in some cases compliance with drinking water regulations.  All ARRA funds have been expended on this p
This agreement provides funding under the American Recovery and Reinvestment Act of 2009 to the State of Nebraska to capatilize its revolving loan fund for the financing of the construction of drinking water facilities, green infrastructure, pr
Capitalization grant  for the Drinking Water State Revolving Fund.  At least 50% of the amount must be used for additional subsidization.  Iowa is providing loan forgiveness for disadvantaged communities.  At least 20% must be used for green pr
Green Project Reserve, DWSRF Loans & Assistance Subsidization
Administration of Drinking Water SRF ARRA projects.
This award provides stimulus funding to the grantee for training of residents for the skills necessary to gain employment with companies that assess and remediate Brownfields properties in the City of Long Beach.
CYPRESS MANDELA TRAINING CENTER (CMTC), INC.
To provide stimulus funding for training of residents for the skills necessary to gain employment with companies that assess and remediate brownfield properties in the City of Oakland.
ARRA Brownfields Job Training Cooperative Agreement
The American Recovery and Reinvestment Act funds were used to assess and address the risks at petroleum releases from leaking underground storage tanks (LUST) sites in the State of Michigan.  The cooperative agreement funded LUST assessments an
American Recovery & Reinvestment Acts (ARRA)-Leaking Underground Storage Tank (LUST)
This agreeement provides American Recovery and Reinvestment Act funds as an additional financial assistance source for the recipient's efforts to assess and cleanup petroleum releases from leaking underground storage tanks (LUST) sites in Idaho
American Recovery and Reinvestment Act of 2009 Idaho Leaking Underground Storage Tanks Sites Cleanup.
This agreement provides American Recovery and Reinvestment Act funds as an additional financial assistance source for the recipient's efforts to conduct site assessment. The cooperative agreement awarded was intended to be 100% Contracted Out.
Leaking Underground Storage Tank Program
Assessment and clean-up of petroleum releases from leaking underground storage tanks (LUST) in Vermont including shovel-ready projects (sites ready for assessment and cleanup) that are typically orphaned or abandoned sites.  In addition, staff
New Jersey Leaking Underground Storage Tank (LUST) Trust Fund of 2009 Project: The New Jersey Department of Environmental Protection (DEP) uses these funds to remediate discharges from regulated LUST.  The most common type of case is a gasoline
Leaking Underground Storage Tank (LUST) ARRA - Financial assistance to assess and cleanup petroleum releases from Leaking Underground Storage Tank sites in Maryland.  Agreement funds several activities, such as shovel ready projects, orphas or
Leaking Underground Storage Tanks (ARRA)
LUST assessments and cleanups throughout Kansas.
LUST American Recovery and Reinvestment Act, Kansas.
The Michigan Department of Education received funds through the American Recovery and Reinvestment Act of 2009 (ARRA) to assist in the purchase of equipment for School Food Authorities (SFAs) participating in the National School Lunch Program (
Michigan Department of Education NSLP Equipment Assistance Grants
The Michigan Department of Education received funds through the American Recovery and Reinvestment Act of 2009 to pay costs associated with the distribution of USDA foods donated for use in The Emergency Food Assistance Program (TEFAP).  Such c
Michigan Department of Education TEFAP CAP Recovery Act
Studies of primary human B cell defects have led to an appreciation of specific stages of B cell development. Commitment to the B cell lineage occurs early in lymphogenesis with selected gene rearrangements in Ig heavy chain genes; these initia
CELLULAR & MOLECULAR DEFECTS IN HUMAN B CELL DEVELOPMENT
To take advantage of the newly established Multiethnic Cohort Study biorepository to conduct biomarker studies of cancer etiology and survival (using blood, DNA, and urine samples) in the Multiethnic Cohort Study.
Molecular Epidemiology of Nutrition and Cancer in the Multiethnic Cohort Study
BDNF and Spine-related disorders of memory and cognition.  Dendritic spines with abnormal morphology occur in various forms of mental retardation and are also found in psychiatric conditions associated with disturbances to memory and cognition.
BDNF and Spine-Related Disorders of Memory and Cognition
This project supports water quality management planning activities authorized under Section 205(j), 303(e), and 604(b) of the Clean Water Act and ARRA of 2009.  Three projects (elements) have been identified to accomplish program objectives: (1
This ARRA grant supports the update of the South Carolina State-wide 208 Water Quality Management Plan for non- designated areas of the State as well as the update of 6 regional 208 Water Quality Management Plans. $118,184 will be used by SCDHE
The State of Missouri will pass-through funds to Regional Planning Organizations. The Request for Proposal (RFP) developed by the Department encourages applicants to give priority to watershed management planning, particularly in urban watershe
604(B) WATER QUALITY MANAGEMENT RECOVERY AND REINVESTMENT ALLOCATION
ASOCIACION NACIONAL PRO PERSONAS MAYORES (INC)
To provide support for the Senior Environmental Employment (SEE) Program enrollees to work in various offices in EPA Region III and to support EPA stimulus activities under the American Recovery and Reinvestment Act of 2009.
SEE Program for Region III Recovery Act Operations/Stimulus Activities
The following is a revised version of RO1 AG013983-22 entitled 'B Cells and Autoimmunity', which has been reduced in scope to pursue research that can be accomplished in two years rather than the originally proposed five years. The previous app
Patients with probable Alzheimers disease (AD) have semantic memory difficulty. In the previous funding period, we demonstrated that this is due to several factors, including degraded knowledge of the features that contribute to concepts; and a
CONCEPTUAL PROCESSING IN ALZHEIMER%27S DISEASE
This is a two-year extension of the Study of Osteoporotic Fractures (SOF) to analyze data, publish results, and continue scientific participation in SOF during the 4th and 5th years of our competitively renewed and (partially) funded 5 year stu
3 of 4: Study of Osteoporotic Fractures (SOF)-Pittsburgh Clinical Center
The long term goal of these studies is to understand how B lymphocytes capable of making antibodies to self tissue are normally prevented from doing so. One form of regulation is receptor editing, in which such cells are reprogrammed to express
The Borrelia are causative agents of important human diseases including Lyme disease and relapsing fever. In N. America, Lyme disease is caused by B. burgdorferi, B. garinii, and B.afzelii and relapsing fever is caused by Borrelia hermsii and B
Immune evasion mechanisms of the Borrelia
Award Title:  Biochemical Mechanisms of Drug Resistance in HIV RT Description:  Nucleosides are an important class of drugs against human immunodeficiency virus (HIV); however, drug resistance is frequently selected during therapy.  Drug resist
BIOCHEMICAL MECHANISMS OF DRUG RESISTANCE IN HIV RT.
T cell activation and tolerance are tightly regulated to assure effective elimination of infectious pathogens while maintaining tolerance to self-tissues. T cell immunity vs tolerance decision is, on one hand, determined by the extracellular si
SIGNAL TRANSDUCTION AND CYTOKINE GENE REGULATION BY GRAIL
Pseudomonas aeruginosa (PA) is one of the two most frequent causes of hospital-acquired pneumonia (HAP), a disease that afflicts 10% of all patients admitted to intensive care units (170). Studies in humans and animal models have shown that the
ExoU and the Pathogenesis of Pseudomonas Pneumonia
HIV disease progression varies widely among individuals. Although some genetic or HIV protein factors have been identified that affect disease progression, these do not explain slow HIV disease progression in most cases. We and others found an
GBV-C Effects on CD4 Activation and Expansion
The C7N-aminocyclitols, a relatively new class of microbial secondary metabolites, have great potential to be developed as drug candidates for the treatment of various physiological disorders (eg, diabetes), infectious diseases (e.g., influenza
Biosynthesis Approach to Novel Bioactive Aminocyclitols
In 2001, our group began studies to determine the genetics causes of bone fragility. We chose to study rats, rather than mice, because the laboratory rat has proven to be an excellent model for human bone disorders, like osteoporosis. Because r
The long-term objective of this proposal is to obtain a better understanding of the molecular mechanisms governing the first step in tumor cell dissemination, namely motility.  To accomplish the we propose to define the structure-functional rel
CHARACTERIZATION OF MOTILITY FACTOR RECEPTOR
Like most other cancers, prostate carcinogenesis involves a multi-step progression from precancerous cells to cells that proliferate locally in an unregulated fashion and then metastasize. Multiple lines of evidence have shown that the effects
Roles of the Androgen Receptor and Its Co-Regulators in Prostate Tumorigenesis
The purpose of the project is to understand the role of Cks proteins in the etiology of cancer. Cks proteins are overexpressed in a broad spectrum of human cancers, yet the reason for this is not known. We are therefore investigating the cellul
Cks Proteins in Cell Cycle Control and Tumorogenesis
The studies of CA076379-11Al will define the mechanisms by which select tumor suppressors are inactivated in different developmental contexts. The studies supported by CA076379-11Al have shown that the Myc oncogene, which is activated in 700k o
Interplay of Myc, Tumor Suppressors and Regulators of Differentiation in Lymphoma
The primary goal of the research in this competitive renewal application is to understand the role of signal transducers and activators of transcription (Stats), particularly Stat3, in epithelial carcinogenesis. During the previous funding peri
Vitamin D has been investigated as a potential preventive therapy for prostate cancer (CaP) because of its many anti-cancer activities.  We demonstrate in the transgenic adenocarcinoma of mouse prostate (TRAMP) model of CaP that early treatment
Vitamin D Analogs for Chemoprevention of Prostate Cancer
Lysophosphatidic acid (LPA), a naturally occurring lysophospholipid, is ligand of at least five G proteincoupled receptors (LPA1-5). The LPA1-3 receptors are members of the endothelial cell differentiation gene (Edg) family and couple to Gi, Gq
During the past 25 years, studies in epithelial cancers have defined genetic changes in the tumor cells themselves. However, it is clear that cancer progression and metastasis requires complex interactions between tumor cells and the surroundin
Role of cPLA2 in Lung Cancer: Microenvironment vs Tumor Cells
Molecules essential for tumor growth and development represent promising targets for novel immunotherapy of cancer, yet host immunosuppressive factors impose major challenges for translating this hypothesis into clinical success. This proposal
IMMUNOREGULATION AND IMMUNOTHERAPY OF BREAST CANCER
Our goal is to understand the regulation of ErbB signaling in endometrial and breast cancers, diseases where amplification of ErbB genes (EGFR, ErbB2, ErbB3) is associated with poor outcome. The composition of the UNM team is unique, with exper
MSM MAPPING AND MODELING ErbH RECEPTOR MEMBRANE TOPOGRA
Calcitonin in Prostate Growth and Neplasia - DESCRIPTION (provided by applicant): Prostate cancer (PC) is the most commonly diagnosed cancer type and the second leading cause of male cancer deaths in the United States. We and others have shown
Calcitonin in Prostate Growth and Neplasia
A major mechanism for regulating the activity of biogenic amine neurotransmitter transporters, the important targets for therapeutic antidepressants and psychostimulant drugs of abuse, is through modulation of the abundance of functional transp
Molecular Studies of Catecholamine Transporters
This project is based on a multidisciplinary, international collaboration to study the role of cannabinoid receptors and the endocannabinoid system in behavior, pharmacology and physiology of cognitive function. The collaboration entails an unp
Cannabinoid Effects on Sensory Processing in Brain
Opioids such as morphine are the most powerful treatment for pain. Unfortunately, the analgesic effects of morphine decrease with repeated administration because of tolerance. Many mechanisms have been proposed to underlie the development of to
Drug addiction is a major illness that penetrates beyond the afflicted individual to families and communities, having adverse effects on millions of people. It exacts enormous costs on our nation?s health care system, economy, and overall produ
Role of Cdk5 in Addiction - ARRA Stimulus 2 Yr Resub
A Qualitative Study of Women Prescription Drug Sellers This Qualitative research project will provide much needed empirical information about women who sell prescription drugs and their unique experiences in order to design more appropriate and
A Qualitative Study of Women Prescription Drug Sellers
The development of the organ of Corti is a tightly regulated process, in which a small 'prosensory' domain of the cochlear duct is sorted into various types of hair cells and support cells. Over the past five years, a model of this process has
NYCDOT operates the Staten Island Ferry (SIF) system that operates between St. George Ferry Terminal in Staten Island and Whitehall Ferry Terminal in Manhattan, New York. It is the largest ferry system nationwide carrying 70,000 on weekdays or
Transit Capital Assistance - Staten Island Ferry System Asset Maintenance
The purpose of the Lead Based Paint Hazard Control Grant Program is to assist the City of Utica in undertaking comprehensive programs to identify and control lead-based paint hazards in eligible privately owned rental or owner-occupied housing,
Tropical coral reefs face a suite of environmental assaults ranging from anchor damage to the effects of global climate change (GCC). The consequences are evident throughout the tropics, where many coral reefs have lost a substantial fraction o
RUI-The ecophysiological basis of the response of coral larvae and early life history stages to global
Award title:  Air-Sea Exchange in the Southern Ocean.  The award supports research on air-sea heat exchange within the Southern Ocean and is expected to contribute to our overall understanding of coupled ocean-atmosphere climate processes.  Fun
Total and dissolved organic carbon (TOC/DOC) are central components of the global carbon cycle, as well as being two important parameters in water and environmental quality analysis.  Accurate measurements of dissolved organic matter are import
Development of a High-Precision TOC/DOC Analyzer With a nM Detection Limit
Collaborative Research: Oceanic Diazotroph Community Structure and Activities in a High Carbon Dioxide World
RECOVERY ACT RESEARCH SUPPORT for the Implication of ANAMMOX Community Structure and Microbial Interactions in Estuarine N removal Processes
Collaborative Research:  ETBC:  Implication of ANAMMOX Community Structure and Microbial Interactions in Estuarine N removal Processes
Collaborative Research: Reconstructing Deep Sea Acidification During the Paleocene-Eocene Thermal Maximum
In the North Atlantic Ocean, poleward transport of equatorial heat is facilitated by both the Atlantic Meridional Overturning Circulation (~90% of total northward heat transport) and the Subtropical Cells (STCs, ~10% of heat transport).  Change
Assessing Wind-driven Circulation Variability in the Subtropical N. Atlantic Using an Array of Archived Radiocarbon Records
This is potentially transformative research that focuses on whether the oxygen isotope ratios in phosphate in DNA record the temperature at which organisms grow. Its purpose is to explore the environmental conditions and temperature optima for
Thermometric Properties of DNA: application to the Deep-sea Biosphere
The PIs propose to study the hypothesis that Rossby basin modes play a significant role in Pacific Decadal Variability (PDV). Baroclinic Rossby basin modes are natural oscillations of the ocean with very large spatial scales and periods of up t
Collaborative Research:  The Role of Basin Modes in Pacing Pacific Decadal Variability
This collaborative project will use the model organism Vibrio fischeri to investigate how marine bacterial communities coordinate responses to changing and varied nutrient conditions, focusing on carbon sources and iron.  Graduate and undergrad
Infrastructure Enhancements for Deep Submergence
The objective of the proposed project is to develop a comprehensive software package for high fidelity direct numerical simulation (DNS) of turbulent combustion with detailed consideration of gas-phase chemistry, soot formation, and spectrally-
Collaborative Research:  Petascale Computing, Visualization, and Science Discovery of Turbulent Sooting flames
We propose to develop the core of a new generation of scalable chemistry and physics codes with an immediate target of the petascale computers now being deployed by the NSF but with a vision that incorporates the exascale computers anticipated
Computational Chemistry and Physics Beyond the Petascale
Collaborative Research: Petascale Computing, Visualization, and Science Discovery of Turbulent Sooting Flames - Basic Research  Energy efficiency, the environment, and human health can be affected by combustion-generated soot, so controlling so
Collaborative Research:  Petascale Computing, Visualization, and Science Discovery of Turbulent Sooting Flames
PI: SuthersInstitution: University of Hawaii at ManoaProposal: 0943147Proposal Title: VOSS Traces--Understanding Distributed Socio-Technical SystemsThis award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5)
VOSS: Understanding Distributed Socio-Technical Systems
VOSS:  Collaborative Research:  Virtual teams, Knowledge management, and team performance  Many knowledge-based organizations depend on virtual teams, whose membership is neither co-located nor stable, to complete the work of the organization.
VOSS:  Collaborative Research:  Virtual teams, Knowledge management, and team pe
Award number OH00300090409R will primarily be used to identify and improve inefficiencies within King Kennedy North High Rise by improving overall indoor air quality, measuring and verifying energy consumption, and by decreasing overall energy
Cuyahoga Metropolitan Housing Authority (OH003) American Recovery and Reinvestment Act Competitive Grant Creation of an Energy Efficient, Green Community
Award number OH00300093009G will primarily be used to coordinate with the other phases of the development of Garden Valley.  Project meetings are currently on-going.  Utilities and site preparation work is currently being coordinated and demoli
The Dayton Metropolitan Housing Authority is implementing the following activities using Capital Fund Recovery Act funding: 46 units of the SCATTERED SITE (OH005000002)public housing development are being rehabilitated; 327 units of SCATTERED S
TRUMBULL METROPOLITAN HOUSING AUTHORITY INC
Comprehensive modernization of family units in Trumbull County.
Conduct Modernization activities at various Public Housing Communities.
Upgrading of buildings and site of two Public Housing Developments (Wayne Hills & Farley Square).  We will be tuck pointing brick & foundations, replacing/ repairing concrete sidewalks & stairs, replacing/repairing fences and roofs.
Conduct modernization activities as various Public Housing Communities. This funding can be expected to result in providing employment for archiects and engineers, and construction workers. In addition, this funding can be expected to substanti
To invest in public transportation by purchasing five replacement small buses (14 passenger), purchasing eight small vans, and purchasing four service vehicles (one service truck and three four-wheel drive vehicles to provide essential services
Purchase of Vehicles, Equipment, Facility Improvments and Preventitive Maintenance
GREATER DAYTON REGIONAL TRANSIT AUTHORITY
To invest in Public Transit by purchasing twenty five replacement 40' low floor public transit buses.  These buses meet or exceed current Clean Air Act (CAA) standards and the American with Disabilities Act (ADA) requirements and will have a se
Preventive Maintenance, purchase of twenty five replacement 40ft diesel buses and purchase of twenty two replacement <30ft medium duty buses.  Approved Operating Assistance.
Invest in public transportation by restoring and preserving a historic New York Central Train Station to become the Lorain County Transportation Center. The Transportation Center will be a transportation hub for Lorain County Transit, Greyhound
Renovate two separate facilities in addition to the purchase of three replacement buses and vehicle GPS/AVL systems. Operating assistance to preserve jobs and service.
PORTAGE AREA REGIONAL TRANSPORTATION AUTHORITY
Invest in public transportation by replacing the roof of a bus storage/maintenance facility, performing preventative maintenance on existing buses and facility, renovation of a training area in the existing garage, and completing preliminary en
ARRA Maint. Facility Rehab./ Preventative Maintenance
Invest in public transportation by purchasing replacement buses and paratransit vans, continuing to perform preventative maintenance on existing vehicles and buildings, further our transit enhancments for our passengers, provide security for ou
Purchase of replacement vans and buses, preventative maintenance, support equipment and transit enhancments
New library wil be supplied with new equipment
The Syracuse Racine Regional sewer District (SRRSD) provides sewer service to approximately 656 customers within the District's boundaries, which includes the Villages of Syracuse and Racine as well as the unincorporated area of Tackerville in
Syracuse Racine Regional Sewer District Rehab and Tackerville Extension Project
2009 Capital Fund Recovery Competitive Grant; Geothermal Installation at Oak Grove; design fees for engineer & management/technical fees for salaries.  Geothermal work includes replacement of existing heating system with energy efficient system
This project provides for the construction of water supply and wastewater disposal facilities for an estimated 34 Indian owned homes located within the boundaries of the Cherokee Nation in Nowata County, Oklahoma, as identified under Sanitation
OK-09-R32 Cherokee Nation; Delaware Water Treatment Plant Upgrade
Citizen Potawatomi Nation Health Center (Shawnee, Oklahoma) Geothermal Retrofit Project: Scope of this project includes a geothermal retrofit for 11,966 sq. ft. of the building which currently has a conventional heat and air system. Scope inclu
OK9CBVC1 Citizen Potawatomi Nation Health Center Geothermal Retrofit Project
comprehensive moderation of family units, a/c replacement, cabinet replacement, and tree removal
Conduct moderization activities at this public housing authority. This funding can be expected to result in providing employment for construction workers and product manufacturers. In addition, this funding can be expected to substantially mode
Capital and Management Activities (Formula) - This award is being used for modernization of the forty-four (44) units of low income housing. Energy efficient air conditioners, ceiling fans, energy efficient water heaters and new doors are being
2007 ANNUAL PLAN, CARPET, PAINTING, FENCES, VENTS, CEMENT WORK
Purchase 119 vinyl storm windows  for 18 apts. and office building which are low E glass.  Install 60 vinyl storm windows in 10 1 Bedroom apts. and 3 in office building.
HOUSING AUTHORITY OF THE CITY OF WAYNOKA
Conduct modernization at various Public Housing developments.  This funding can be expected to result in providing employment for architects and engineers, construction workers and product manufacturers.  In addition, this funding can be expect
conduct modernization including new storm doors, new heating systems for 6 units and carpet for 10 units
ARRA Capital Fund Program: to conduct modernization activities at various Public Housing developments. Yale Housing Authority's purpose is to replace kitchen cabinets in 10 family units and replace HVAC in 5 units with new energy efficient HVAC
Conducted modernization activities in this jurisdiction for The Housing Authority of the Town of Lone Wolf, Kiowa County, Oklahoma. This provided employment in the United States for contruction workers who removed 26 year old masonite siding fr
The Oklahoma Department of Transportation will invest in public transportation by replacing the nonurbanized and rural transit provider's aging fleet with efficient and reliable vehicles. A total of 248 vehicles will be purchased. The purchase
Purchase of 243 replacement buses and five over-the-road intercity buses.
Prepare and paint clinic and wellness center.
Bearskin Indian Health Ctr Renovation and Painting
Modernization of 5 public housing assest management projects. Work shall include:  Contract administration, project management, asbestos/mold testing and abatement, roof @ community center, installation of high speed data line, seal coat two pa
CENTRAL OREGON REGIONAL HOUSING AUTHORITY
Modernization of 20 public housing units at scattered sights in Bend and Madras Oregon
TRI-COUNTY METROPOLITAN TRANSPORTATION DISTRICT OR
Invest in public transportation by initiating Street Maintenance Improvements for Bus Priority; a Park & Ride in the City of Milwaukie; Concrete Bus Pads and the Foster Road Bus Layover; Lighting along Multi-Use Path adjacent to the I-205 Light
Street Maint Improve; Milwaukie Park&Ride; Foster Rd Layover Concrete Bus Pads; Lighting along Multi-Use Path adj to I-205 Light Rail Tracks; Morrison/Yamhill Intersect Repairs; Portland Streetcar Signals; Rail Trestle Repair; Train Horn Noise
Salem Area Mass Transit District is making an investment in public transportation through the following projects:  purchase of three (3) 35-foot fixed route buses (the Transit District initially applied to purchase four (4) buses, but the numbe
Furnish all plant, labor, material, and equpment necessary to install Demand Ventilation Controls per speifications from Projects VKAG 08-1048
Repair Taxiway Center Slabs - 5057-B, Repair Runway/Taxiway Slabs, Poly Panels - 5057-A.  To replace concrete slabs full depth on runway, spall fields on F-15E Apron, Transient Alert Apron, Taxiway B and Taxiway J to be repaired.
Install Concrete Pad.  Mobilize, saw cut and construct a concrete pavement including painting as per drawings.
Repair Base Electrical Distribution - Phase 12
Furnish all labor and materials, equipment and services required to paint the exterior,interior and the gutters/downspouts of Facility #546.
Repair Electrical U/G Georgia Street/Mitchell Blvd.
Mill and overlay taxiway, install crack and joints seals and paint airfield markings.
ductile iron pipe line, backfill, compaction, paving, striping, site restoration. A portion of the asphalt paving was deleted at the last minute from this project resulting in a decrease to the contract value.
REPAIR FAIRCHILD AVE PAVEMENT FROM AIRLIFTER TO THE 381ST PHASE 1 AND 381ST TO GREEN LAKE PH 2, ELMENDORF AFB, ALASKA.
UPGRADE TRAFFIC SIGNAL AT SIJAN & ARCTIC WARRIOR DRIVE, ELMENDORF AFB, ALASKA.
07-1071 Replace Complete HVAC System at Base Ops
TO 5082-Recovery-FTQW071071-Repair HVAC System, Base Operations. Provide all labor and materials required to remove and replace existing inadequater heat and ventilation systems at Base Ops., Bldg 1215.  Design and install new heating and venti
01-2542 Install Bldg. 4378 Fire Suppression System
Provide all labor and materials required in order to design and install a fire sprinkler system for the Hazmat Decontamination Facility, Bldg. 4378.
TO 5089-Recovery-FTQW071079-Repair H-Frame Transformer, CHPP Pump House
Repair the roof of Bldg 6203 by EPDM replacement including modification for asbestos abatement
Paint Exterior Building 1335 Hickam Air Force Base (Youth Center)
Furnish labor, materials & equipment to remove and dispose of the loose and flaky paint at exterior of Hangers 15/17 - UNITEK INSULATION, LLC.
Repair O'Malley Blvd, Outbound, Hickam Air Force Base, Hawaii; Repair HMA pavement; Repair concrete curbs; New pavement striping
Maintain Roadway Pavement Markings, Hickam Air Force Base, Hawaii
Repair Lighting-Energy Efficient Upgrades-Phase II
Maintain Roadway Pavement at Andrews Street, Hickam Air Force Base, Hawaii
T. O. # 3002, Project # AJJY 09-1125, Install Lightning Protection System, Andersen AFB, Guam
Replace deteriorated asphalt pavement, Taxiway  Charlie Hardstands (C18, C20, C22,C24,26) AJJY 02-1103E
RECOVERY - SHCZ050040-REPAIR BY REPLACEMENT ENGIN FOR FIRE PUMP
Project chiefly comprised of the construction of concrete and masonry barrier walls for anti-terrorism/force protection measures.
Perform misc repairs on cooking hoods to correct fire deficiencies in dining facility Building #5905.
Widen Right Turn Lane At Air Depot and Arnold Ave.
ROOFING REPAIRS - BLDG 2122 CORROSION CONTROL.
Paving Wardleigh, South Gate to Chenault
HARMON COMMERCIAL AND INDUSTRIAL CONSTRUCTION, INC
Maintain/Paint the Waste Water Plant Facilities
high on walls in restroom area. Install a mop sink in room #2116. Patch, prep, &and paint area vanity and medicine cabinet was demoed. 7. Install new elongated commodes. Paint doors & install new privacy lockset. Room #?s 2113; 2115 & 2109 - D
Enclose open storage bays east of the existing closed bay siding panel. Install siding and new doors as located on Govt. provided drawing and final approval from Saber PM. Demo completely and dispose the asphalt area within the entire proposed
Remove 28 each existing 120 volt, 150 watt high pressure sodium light fixtures in the basketball court area of B. 827. Install 28 each new 120 volt 400 watt metal halide fixtures. Inspect existing down rods, wiring, and safety clamps and reuse
Purchase/Install Centravac Centrifugal Chiller Unit, Bldg. 177
TAS Recovery Project #UHHZ070219:Repair/Replace roof, LOG Facility Dep Operations,Bldg 300, Robins AFB, GA. The purpose of this project was to repair the roof of bldg. 300 at Robins AFB. Services performed/supplies delivered include: the labor
Repair or replace windows and paint the exterior of bldg 220, Robins AFB.
Perform according to the scope of work on each individual task/delivery order.
The impact of advanced materials and processes on fuel burn for fielded and developmental gas turbine propulsion engines will be determined using analytical engine cycle models of representative engine classes.  The model results will provide t
Program Title:  Adaptive Combustor Technology for the High Energy Efficient Turbine Engine (HEETE) Program  The objective of the Adaptive Combustor Program for HEETE is to explore the combustion technologies needed for a combustor that can tail
Inspect seven bridges at AEDC as specified in the following locations:\ 1. Wattendorf Memorial Hwy. at Bradley Creek 2. Brick Church Rd. at Brumalow Creek 3. Wattendorf Mamorial Hwy. at Rowland Creek 4. UTSI Road and Rowland Creek 5. Wattendorf
Recovery Upgrade Steam Plant A. Arnold AFB, TN Tullahoma, TN 37388-5570
Site Demolition and Interior Construction
Replace existing interior light fixtures and exterior light fixtures w/new energy-efficient flurescent fixtures.
Interior construction, Stairways, Interior finishes, Plumbing systems, Furnishings, Selective demolition and General Requirements.
objective: eliminate septic and holding tanks by provide access to a gravity sewer along Contractor's Row.
The Air Force Flight Test Center at Edwards AFB, CA, has requested that the following work be performed in Building 1398. This work includes but is not limited to: Provide and installation of (5) new fan coils (facility), (1) new 300MBH (output
This is a comprehensive and collaborative computational and experimental program to investigate the characteristics and dynamic behavior of novel energetic propellants for space propulsion. Several classes of advanced propellants are being cons
VETERANS' AFFAIRS, VIRGINIA DEPARTMENT OF
General Renovation resulting in upgraded and expanded facilities for resident care and services.
GRIND EXISTING PAVEMENT, PLACE BASE ROCK AND APPLY TWO 2 IN LIFTS OF PAVEMENT
Maintenance of genome stability is of paramount importance; genome instability has been correlated with numerous disease states in humans, for example. Repetitive DNA is often the source of genomic rearrangements. One class of repetitive DNA, m
Factors controlling minisatellite stability in yeast
Histones are the major scaffolding proteins which organize and compact nuclear DMAin chromatin. These proteins undergo numerous types of chemical modifications that govern a variety of processes in the nucleus. Methylation of the amino acid lys
STRUCTURE AND FUNCTION OF SET DOMAIN METHYLTRANSFERASES
Polarity establishment and oriented cell divisions are central to the development of many organisms. Cells of the budding yeast S. cerev/s/ae exhibit two distinct patterns of budding depending on their cell type, reflecting genetic programming
(ARRA) REGULATION OF POLARIZED CELL GROWTH BY GTPASES
. Proteins are likely to organize into complexes that assemble and disassemble depending on cellular needs. However, proteins must also avoid catastrophic aggregation, which underlies many important diseases (e.g., Alzheimer's & prion diseases)
CELL CHIPS FOR GENOME-WIDE PROTEIN AND RNA LOCALIZATION IN SINGLE CELLS
This project seeks to continue the development and maintenance of the dChip software, which analyzes and visualizes oligonucleotide gene expression and SNP (single nucleotide polymorphism) microarray data. We have developed dChip as a software
dChip: Analysis and Visualization of Oligonucleotide Expression and SNP Arrays
We will determine whether quantitative genetic interactions from the X contribute to allele specific transcript varaition. By sampling from a set of 3rd chrosomoe introgression lines we will determine whether interactions from an autosomal regi
Genetic Variation of https://www.federalreporting.gov/federalreporting/secure/createReport.do?showPrimeRecipient=Allele-Specific Transcriptions in Drosophila
This administrative supplement requests funds to accelerate research on the structural dynamics of multidrug ABC tranporters (R01-GM077569). Active drug extrusion by multidrug transporters is one of four general mechanisms associated with the m
Structural Dynamics of Multi-Drug Resistance ABC Transportors
Inter-species comparisons of gene expression levels will increase our understanding of the evolutionof transcriptional mechanisms and help to identify targets of natural selection. This approach holdsparticular promise for apes, as many human-s
NATURAL SELECTION ON GENE REGULATION IN HUMANS
The dorsal root ganglion ??DRG?? is composed of a heterogeneous population of sensory neurons that occupy distinct niches within the somatosensory nervous system. This heterogeneity represents a significant challenge to investigators interested
Electrophysiology of peripheral nerve sodium channels
1. Purpose of the supplement - This is a request for salary support for a postdoctoral research associate to continue work begun on this project by a former postdoctoral fellow. The former postdoctoral fellow was a vital component of our curren
The Role of Arf GTPases in Endocytosis and Postendocytic Transport
PHYLOGENETIC ANALYSIS WITH COMPLEX GENOME REARRANGEMENT EVENTS With the support of administrative supplement from NIH, we will conduct research on mathematical modelings of genomic duplication and individual gene loss, with the aims to find new
PHYLOGENETIC ANALYSIS WITH COMPLEX GENOME REARRANGEMENT EVENTS
In membranes, proteins and lipids form an integrated system to support essential cell functions.  Tranmission electron microscopy is the only technique to determine the structure of proteins in their native lipid environment.  Recently the stru
Influence of lipids on membrane protein structure and function
The goal of this supplement is to identify the genetic variants contributing to inter-individual variation in GCmediated transcriptional response and to determine if these variants were targets of genetic adaptations to different local environm
Pre-mRNA splicing is essential for gene expression in all eukaryotes and errors in splicing cause genetic disorders and many other diseases. Mutations in splicing factor Prp8, for example, cause a severe form of human genetic disorder Retinitis
Understanding the structure and function of splicing factor Prp8
The research project focuses on the development of efficient chemoenzymatic methods for synthesizing N-glycopeptides and N-glycoproteins of biomedical significance. N-linked glycosylation is a major posttranslational modification of proteins in
Convergent Chemoenzymatic Synthesis of Glycopeptides and Glycoproteins
Double-strand breaks (DSBs) are deleterious DNA lesions that occur spontaneously or are induced by chemicals or irradiation. DNA recombination is an essential process that repairs DSBs. There are two pathways of DSB repair, homologous recombina
REGULATION OF DNA RECOMBINATION IN SACCHAROMYCES CEREVISIAE
The long-term goal of this project is to understand the underlying signaling mechanisms of cell intercalation, in which neighboring cells change their shapes to become intercalated with each other. Cell intercalation is critical for the proper
Signaling to Cellular Intercalation in Arabidopsis
RECQ HELICASES AND GENOMIC INSTABILITY The general goal of the parent grant for which this supplement is requested is to increase our understanding of how genomic stability relates to aging, development, and cancer. Our research focuses on the
Linkage disequilibrium (LD, the non-random association of alleles at two or more loci) provides valuable information for detecting genetic variations that are responsible for complex human diseases such as hypertension, diabetes, obesity, and s
GENOME WIDE HAPLOTYPE ASSOCIATION ANALYSIS
Specific Aim 2 of the parent project involves mechanistic studies of the N-terminal antibody binding domain of Staphylococcal protein A (SpA-N).  This 291 residue protein is composed of five nearly identical 56 Ð 61 residue domains. The propos
Mechanistic Studies of Complex Protein Folding Reactions
This is an ARRA Adminisitrative Supplement to an active grant entitled Dynamic Eukaryotic Replication Machines? (R01 GM082849-02).  The major goal of the parent grant is to define the mechanism by which the eukaryotic clamp loader, replication
The ATP synthase is a membrane-bound, energy-coupling rotary motor that is responsible for the synthesis of most cellular ATP in animals, plants and many bacteria. It consists of two sub-complexes with distinct, partial functions: the FO comple
ARRA: Energy Coupling and Regulation in the ATP Synthase of E. Coli
DESCRIPTION (provided by applicant): Our long-term goal is to understand the mechanisms by which molecular motors drive directional traffic along cytoskeletal filaments in the crowded cellular milieu. Specifically, we aim to understand how kine
SINGLE-MOLECULE ANALYSIS OF KINESIN MOTORS IN LIVE CELLS
Abstract Organisms have evolved a number of molecular surveillance pathways to monitor and prevent cellular damage. One such system is the nonsense mediated decay (NMD) pathway. NMD functions to detect mRNAs with premature termination codons, s
ANALYSIS OF NONSENSE MEDIATED MRNA DECAY IN DROSOPHILA
The parent grant proposes to determine the molecular mechanism of adenylyl cyclase VII (AC7) regulation by the G13 pathway and to determine the physiological functions of AC7 in the immune system. Results from these studies in the long run will
Regulation of adenylyl cyclase VII and its function in the immune system
Tremendous advances in ion channel research have been made with respect to channel structure and function. However, there is a lack of information regarding how living cells process ion channel proteins in real time. Such information is importa
Kv2.1 membrane corrals:Regulators of K+ channel function and trafficking
This administrative supplement was awarded to advance the pace of scientific discovery of the parent grant 1RO1GM084244001A1, entitled 'Role of Deubiquitination in Fanconi Anemia Cancer Susceptibility Pathway'.  The parent grant is focused, in
Role of Deubiquitination in Fanconi Anemia Cancer Susceptibility Pathway
This application is submitted in response to the Notice Number (NOT-OD-09-058): NIH Announces the Availability of Recovery Act Funds for Competitive Revision Applications. The overall objective of this Competitive Revision (CR) application is t
MOLECULAR MECHANISMS REGULATING NONCANONICAL NF-KB SIGNALING
that self-renew and establish metastases. A critical regulator of stem cell numbers in mammals is the JAK/STAT pathway. Inappropriate activation of mammalian JAKs and STATs cause cancer and inhibiting their activity blocks the growth of primar
Elucidating the molecular mechanisms that regulate stem cell numbers in vivo
The goal of this administrative supplement was to accelerate our work on the underlying R01 grant application, in which we are attempting to make potent small molecule PDI inhibitors that can be tested in mouse models of neurodegeneration. Our
Scavenger receptor BI (SR-BI) is an HDL receptor that regulates HDL cholesterol levels by mediating the delivery of HDL cholesterol esters to the liver. We recently report a novel and potentially clinically important function of SR-BI in protec
The principle long-term objective of this project is to provide a detailed biophysical and molecular understanding of exocytotic vesicle fusion and transmitter release in endocrine cells and nerve terminals. Upon electrical stimulation nerve te
MECHANISMS OF FUSION AND TRANSMITTER RELEASE IN NEUROSECRETION
Although recent advances in genomics have revealed a tremendous amount of nucleotide polymorphism, little is known about why genes segregate for variants that influence quantitative traits. This proposed research seeks to determine which evolut
Molecular causes and fitness consequences of complex trait variation
B and T lymphocyte development is driven by V(D)J recombination, a process by which gene segments at the antigen receptor loci are repeatedly rearranged to create a vast repertoire of antigen receptor genes. Because V(D)J recombination entails
Co-ordination of recombination and allelic exclusion at lgh and lgk loci
General anesthesia is typically considered to be a rapidly and completely reversible state. The demonstration of anesthetic preconditioning against ischemia makes it clear, however, that anesthetic agents can alter molecular and synaptic events
Mechanisms of Post-Anesthetic CNS Dysfunction in Aging.
This fund is an ARRA administrative supplement to 54066D entitled, 'Language, Modality and the Brain.' The supplement provides summer research experience for students and science educators and will investigate: a) the neural substrates underlyi
ARRA: Language, Modality, and the Brain - Student Summer Research Supplement
This administrative supplement requests funds for an SRI EyeLink II eye-tracker to expedite research on NIH HD 27206, along with an upgrade to make the eye-tracker portable and software to facilitate experimental design and data analysis and s
COORDINATING INFORMATION IN SENTENCE PROCESSING
Regional Differentiation during Forebrain Development - ARRA Project is to accelerate research that will define the niche and transcriptional network necessary for specification of olfactory epithelial (OE) neural stem cells.  The funding actio
Regional Differentiation during Forebrain Development - ARRA
Iron deficiency remains one of the foremost nutrient deficiencies in children in the world. Whereas over 40 studies have described the effects of postnatally acquired dietary iron deficiency on neurodevelopment, less attention has been paid to
Throughout life, descending activity from the brain shapes spinal cord reflexes to support effective motor function. When injury or disease impairs this long-term supraspinal control, reflex patterns are distorted and spasticity and other disab
Supraspinal Control of Spinal Cord Plasticity
Early detection of Autism Spectrum Disorders (ASD) has come to be recognized as a crucial activity in promoting the best possible outcome for affected children. In our current NICHD-funded Early Detection (ED) study, for which this application
Early Detection of Pervasive Developmental Disorders
This proposal is a request for a Recovery Act administrative supplement to an existing NIH grant providing summer research experiences for students and science educators. It is proposed to support the summer employment of an undergraduate stude
Role of LHX3 Protein Isoforms in Pituitary Development
The diversity of cell types within the vertebrate nervous system depends on patterning events that occur at early stages of development. The specification and patterning of neural tissue is closely coupled to the development of the other germ l
ARRA: Genetic and Molecular Analysis of Neural Development
Although prior research has demonstrated that relationship characteristics and partner type (e.g., casual vs. primary sexual partner) are associated with HIV risk behavior, the role of relationship dynamics in sexual risk behavior has only begu
Relationship Dynamics and Sexual Risk Behaviors
The aims of this study are to evaluate the interaction of temperament and dietary factors in early human development in order to determine their impact on weight gain. The increase in pediatric obesity is of great concern, as close to 6 million
Child Temperament and Diet: Predictors of Weight Gain
We propose that folic acid and the folate methylation pathway play an essential role in repair and recovery of the injured adult CNS, and aim to investigate this relationship with the long-range goal of establishing the mechanism of action of f
ARRA Folic Acid Enhances Repair Mechanism in the Adult CNS
Oral contraceptives (OCs) are one of the most effective, safe and widely-used contraceptive methods available to women worldwide. The US differs from many other countries in that women still need a healthcare provider's prescription, often requ
Oral Contraceptive Use along the US-Mexico Border
It is proposed to study racial and ethnic differentiation in U.S. cities in 1880, with a particular emphasis on the relationships between people and places. The project will use full-count census data from the U.S. Census of Population in 1880
INCORPORATING IMMIGRANTS AND MINORITIES INTO LATE 19TH CENTURY CITIES
The purpose of this supplement request is to facilitate and accelerate acquisition of data essential for moving forward our understanding of mechanisms responsible for pelvic pain. This will be accomplished by using technologies and approaches
Female Pelvic Pain, Hormones, and Neuroplasticity
The purpose of the requested supplement is to provide summer research experiences for a junior faculty member and 3 undergraduate students from Rhodes College.  The participants from Rhodes College will assist research staff and graduate studen
NEURAL CORRELATES OF READING IN MEDULLOBLASTOMA SURVIVOR
Fragile X Syndrome (FXS) is the most common inherited form of mental retardation and is caused by loss of function mutations in the Fragile X Mental Retardation gene (FMR1). Patients with FXS as well as other forms of mental retardation have an
Study of Fragile X Mental Retardation Protein in Synaptic Function and Plasticity - ARRA Stimulus Admin Suppl
Fertilization is biological process with important medical, social and economic implications. From extensive study, the events of fertilization are known in some detail. However, the molecular underpinnings of these events generally remain elus
Gamete Interactions in Caenorhabditis Elegans
DESCRIPTION (provided by applicant): People with Down syndrome (DS) are usually in the lowest 2% of the population in intellectual ability, yet their language ability is far lower than their intellectual ability. Severe language limitations hav
Cognitive Predictors of Lanaguage Impairment in Down Syndrome
This project will develop a comprehensive array of new statistical methods for analyzing genome-wide association studies, and will apply these methods, and other appropriate methods, to perform in-depth analyses of NIH-funded association studie
GENOME ANALYSIS:  DATA ACCURACY HAPLOTYPING AND MAPPING
The funds we were granted will cover the analysis of protein complexes from adult transgenic flies. These results will be compared and contrasted with analogous protein maps established from S2 cultured cell lines. The combination of in vivo an
The Protein Complex Map of the Drosophila Proteome
The grant addresses two research areas directed towards significant performance improvements of the single-molecule, real-time (SMRT) DNA sequencing technology we have developed through funding by the original grant. They pertain principally to
Real-Time Multiplex Single-Molecule DNA Sequencing
ARRA - Rapid Genetic Engineering of Stem Cells  Description: The production of murine models by means of gene-targeting embryonic stem cells is a fundamental tool in biomedical discovery.  The parent grant ?Rapid Genetic Engineering of Stem Cel
ARRA - Rapid Genetic Engineering of Stem Cells
In patients with chronic thromboembolic pulmonary hypertension (CTEPH), elevated pulmonary vascular resistance (PVR) is caused by obstruction of proximal and distal pulmonary arteries with thromboemboli, and by pulmonary vascular remodeling due
CAPACITATIVE CA2+ ENTRY AND TRP CHANNELS IN THROMBOEMBOLIC PULMONARY HYPERTENSION
Restenosis, or re-narrowing of the arterial lumen following vascular interventions to treat atherosclerosis, produces significant mortality and morbidity for thousands of individuals.  Transforming growth factor-beta (TGF-b) is an important med
ARRA TGF-Beta in Intimal Hyperplasia after Vascular Bypass
2 year supplement to NIH R01 HL071626 for summer employment and research supplies. The student (Kyle Loftus, a sophamore at South Dakota State University) learned laboratory techniques and skills and began an independent research project which
Caveolin-1 and no regulate PMN-Mediated Increases in Vascular
The goal of our parent RO1 grant is to determine mechanisms regulating cell fate determination in the tracheobronchial stem hierarchy. Ongoing studies indicate that ?-catenin is stabilized during the transition from phase 1 (basal cell) to phas
Wnt Regulation of Tracheobronchial Regeneration
. The identified student will join our laboratory team, which conducts research into the structure and function of blood coagulation factor IXa. The work that will be involved with this summer research is directly related to all three Specific
Fas-induced apoptosis plays an important role in the pathogenesis of several human diseases such as pulmonary fibrosis.  Pulmonary fibrosis is a chronic incurable lung disease that progresses relentlessly leading to death from respiratory failu
Regulation of Fas-Mediated Lung Cell Apoptosis
The purpose of the supplement is to accelarate the structural studies of mitochondria affected by Barth syndrome. These studies have shown extraordinary promise and they are of crucial importance for the overall project, i.e. the investigation
The purpose of the award was to support a pre-dent undergraduate or prematriculating dental student for a summer research experience. The student was expected to participte in an ongoing research project of a parent R01 grant that seeks to eluc
Structural Basis of Serpin Function and Regulation
To improve the outcome of trauma victims and of patients undergoing high-blood-loss surgical procedures and to avoid the many serious complications of blood transfusions, there is a critical need for an oxygen- carrying blood substitute. This s
(ARRA) Mechanically stable blood substitutes
Despite compelling evidence of the benefits of treatment, hypertension is controlled in less than 1/4th of US citizens. Inadequate blood pressure control results in excess cases of coronary artery disease, congestive heart failure, stroke and o
Financial Incentives to Translate ALLHAT into Practice
We started paying salaries for the two associates (Neeco Palmer and Carl Schubert) on October 1, 2009, as planned. We have also obtained many Taqman assays and made preparations for genotpying. However, the major snag has been ordering the equi
Biventricular Pacing After Cardiopulmonary Bypass
Force development during striated muscle contraction is initiated by the binding of Ca2+ to the specific sites in troponin C (TnC), triggering a series of functional structural changes within the thin filament, including opening of the N-domain
KINETICS OF CARDIAC MYOFILAMENT ACTIVATION
APIARY RD: MP 14 - MP 19 PAVEMENT RESURFACING
RESURFACE SECTIONS OF AUBURN RD,HAZELGREEN RDSTATE ST,TURNER RD,CENTER ST,WARD DR&BROWN RD
MARION COUNTY & KEIZER: PAVEMENT RESURFACING
INSTALL NEW SIGNAL HEADS AND HARDWARE, REPLACE ILLUMINATED SIGNS AT VARIOUS LOCATIONS
PURCHASE/INSTALL VIDEO DETECTION EQUIPMENT AT 20 EXISTING TRAFFIC SIGNALS (INC TIGARD)
Immediate Office of the Secretary of Health and Human Services
UNIV OF TEXAS HEALTH SCIENCE CTR AT HOUSTON - SP UT Professional Building BAU Upgrades
NEW YORK CITY HEALTH AND HOSPITALS CORP - JACOBI MEDICAL CENTER - Data Center Build & Security
HOUSING AUTHORITY OF THE CITY OF BRADENTON FLORIDA
Purchased a roll tarp for dump trailer, Phase I environmental for future ARRA work, new compressors and coils for HVAC units, purchased new ranges and refrigerators.  Work began on the non-dwelling conversion to dwelling space and exterior pain
this award will supply solar power water at the laundromat.  It will replace all toilets, faucets, showerheads with water saving devices.  Ceiling fans and programmable thermostats will be added to each unit.
The purpose of this grant is for facilitating the transformational energy efficiency and green retrofits to extensively increase energy efficiency and environmental performance of public housing properties.   The activities slated to be accompl
Capital Fund Recovery Competition Grant City Wide Energy Equipment
The Broward County Housing Authority (BCHA) is implementing the following activities using Capital Fund Recovery Act funding at the management office and 6 public housing units of the SCATTERED SITES (FL079000077) development and are being reha
HOUSING AUTHORITY OF THE CITY OF KEY WEST
Conversion of non-dwelling space to 8 dwelling units.  Repace windows and doors.
J. Y. Porter Place / Ft. Village & R. Gabriel
HOUSING AUTHORITY OF CITY OF MIAMI BEACH (INC)
Conduct modernization for the Public Housing development; pressure wash and paint exterior; replacement of toilets to water conserving toilets; replacement of VCT tiles
Renovations to elderly units including installing low flow faucets and energy efficient lighting.  Truck for FA Mod use on project and material moving.  Replace emergency generator on 12 story elderly hirise.
To provide assistance to the PHA in carrying out capital improvements at Public Housing developments, in accordance with the requirements of the ARRA, that would improve the condition of our properties, in order to ensure that such developments
Modernization of vacant units to include replacing floor covering, doors, appliances and light fixtures to provide more energy efficient dwellings.
HOUSING AUTHORITY OF THE CITY OF DAYTONA BEACH, FLORIDA, THE
2009 ARRA - CFRG To be utilized in modernization activities for the installation of a Fire Suppression Sprinkler System at our two, 13 story hi-rise apartment public housing buildings as required by the Florida State Fire Marshall.  The funding
HOUSING AUTHORITY OF THE COUNTY OF FLAGLER
Public Housing Capital Fund Stimulus Recovery
Funding to provide upgrade @ public housing
Public Housing Capital Fund Stimulus (Formula)
ARRA - Expansion and replacement buses, Overhaul buses,Renovate and upgrade facilities and properties, Maintenance equipment, and operational activities
ARRA - Expansion and Replacement of various sizes of Buses, Renovate and upgradeFacilities
Invest in public transportation by purchasing 10 new low sulfer diesel buses and 3 mini-buses.
Invest in public transportation by constructing new transit facility and security fencing, performing preventive maintenance on existing revenue fleet, installing automatic passenger counters on existing revenue vehicles, installing automated f
ARRA Wythe I77 Resurfacing/Guardrail Upgrades
ARRA Chesapeake/Norfolk I464 Resurfacing/Guardrail Upgrades
ARRA- City of Salem, Roanoke River Greenway
ARRA - CHESAPEAKE CITYWIDE PAVEMENT RESURFACING
ARRA - York 134/716/ 690 Construct Sidewalks
PAVEMENT RESTORATION INCLUDES SIGNING, SIGNAL LOOPS & ILLUMINATION
OR213:I-205(E PORTLAND FWY)-REDLAND RD-CONWAY DR
PREP, SCRAPE, PRESSURE WASH , PRIME AND PAINT EXTERIOR BUILDING ACCORDING TO STATEMENT OF WORK GIVEN
UNIVERSITY SETTLEMENT SOCIETY OF NEW YORK INC
Title:  ARRA Supplemental Funding for the Child Care and Development Fund (CCDF); Description:  The CCDF ARRA funds will be used to provide child care financial assistance to low-income working families and fund activities to improve the qualit
The purpose of the CSBG program is to provide a range of services and activities having a measurable impact on causes of poverty in local communities.  CSBG Recovery Act funds shall be distributed as pass-through grants to eligible entities ser
IdahoSTARS Project Description: To establish a comprehensive, coordinated, high quality professional development and child care resource and referral system in Idaho that: 1) builds the developmental assets of young children with and without di
SOCIAL AND REHABILITATION SERVICES, KANSAS DEPT OF
Title: ARRA Supplemental Funding for the Child Care and Development Fund (CCDF); Description: The CCDF ARRA funds will be used to provide child care financial assistance to low-income working families and fund activities to improve the quality
ARRA SUPPLEMENTAL FUNDING FOR CHILD CARE AND DEVELOPMENT FUND (CCDF); PROVIDE CHILD CAE SERVICES TO LOW-INCOME FAMILIES.
ARRA Supplemental Funding for the Child Care and Development Fund (CCDF); Provide child care financial assistance to low-income families with parents who are working or actively attending education or training programs and fund activities to im
ARRA Supplemental Funding for the Child Care and Development Fund (CCDF): Provide child care financial assistance to low-Income working families and fund activities to improve the quality of child care.
The CSBG ARRA funds were used to provide services and activities addressing employment, education, housing, nutrition, health, and emergency services.
Reduction of poverty, revitalization of low-income communities, empowerment of low-income families.
Benton/Franklin Community Action Committee 	Employment Provide classroom training on job seeking skills, resume writing and interview skills. 	Employment Support 		Provide GED, transportation, health care and food assistance. 	Community Engagem
LEGISLATIVE OFFICE OF THE STATE OF WEST VIRGINIA
Administered through the Office of Community Services of the of DHHR's Administration of Children and families -- 99% ($11, 081,304) of the Community Service Block Grant (CSBG) American Recovery and Reinvestment Act (ARRA or Recovery Act) funds
WV Governor's Office of Economic Opportunity - CSBG ARRA Grant
ARRA Supplemental Discretionary Grant Award for the Child Care Development Fund
This is a proposal under the USGS Program Announcement 09HQPA00021 for upgrading existing earthquake monitoring systems operated by Saint Louis University as part of the US Geological Survey Advanced National Seismic System. In addition to upgr
Upgrade of Some ANSS Seismic Stations in the Central U.S.
The Center for Earthquake Research and Information (CERI) at the University of Memphis operates 139 seismographs in two seismic networks to monitor seismic activity in the New Madrid and East Tennessee Seismic Zones (NMSZ and ETSZ respectively)
This proposal requests Government Furnished Equipment (GFE), funding for installing this equipment  and other upgrades of the Southern California Seismographic Network (SCSN), a cooperative project  of Caltech and the Pasadena office of the U.
Upgrade of Joint USGS-Caltech Southern California Seismic Network
Title:  ARRA Supplemental funding for Child Care and Development Fund (CCDF; Description:  The CCDF ARRA funds will be used to provide child care financial assistance to low-income working families and fund activities to improve the quality of
Social Services Child Care & Development Fund
Dept of Health & Human Services Administration for Children & Families Community Services Block Grant-Project Empower. This funding was used primarily to train individual tribal member in weatherization.  It is planned to hire up individuals fr
The majority of the award will be used to fund more child care vouchers to allow parents to continue working. Also the vouchers will allow parents who are unemployed to receive help with child care up to 12 hours a week to look for employment.
ARRA additional discretionary funds for CCDF
ARRA Supplemental Funding for the Child Care and Development Fund (CCDF);  Provide child care financial assistance to low-income working families and fund activities to improve the quality of child care.
Under the Recovery Act our goal is focused on efforts of creating sustainable economic resources in our community.  The Rosebud Sioux Tribe  will reach the goals of the Community Service Block Grant program by extending services and creating mo
Rosebud Sioux Tribe Community Service Block Grant Stimulus, American Recovery and Reinvestment Act of 2009
Delivery of 66 nonmetallic waterproof cases in support of the Hawaiian Volcano Observatory
All Other Plastics Product Manufacturing
This Administrative Supplement will accelerate the tempo of scientific research by providing funds that will allow us to capitalize on recent data acquired and published by our laboratory. The observation that Hck/Fgr/Lyn-/- mice were better at
DECTIN-1 AND IMMUNITY AGAINST PNEUMOCYSTIS CARINII
This administrative supplement request under ARRA is to support summer students in 2009 and in 2010 for the REasons for Geographic And Racial Differences in Stroke-Myocardial Infarction Study, R01HL080477. The parent R01 will end April 30, 2011
The beta 1 and beta 2 adrenergic receptors are members of the super-family of G protein-coupled receptors (GPCRs). This receptor super-family comprises some of the most important pharmacological targets for the treatment of cardiovascular (e.g.
E3 LIGASES AND DEUBIQUITINASES IN GPCR DOWNREGULATION
The integrity of the blood-brain barrier (BBB) is critical for normal brain function. Neuropathological disorders in AIDS patients have been associated with perivascular HIV-infected macrophages, gliosis and abnormalities in the permeability of
HIV-1 GP120-MEDIATED INJURY IN BRAIN ENDOTHELIUM
Cardiac remodeling is triggered in response to mechanical stress and various neurohumoral factors. We have recently discovered that protein kinase D (PKD), which has been scarcely studied in cardiomyocytes, plays a significant role to regulate
PKC-EHN-PKD SIGNAL COMPLEX IN CARDIAC REMODELING
The injured human heart has an extremely limited ability to repair itself through regeneration of cardiomyocytes.By contrast with mammals, we found a few years ago that the teleost zebrafish displays a highly efficient regenerative response to
REGULATION OF MYOCARDIAL REGENERATION IN ZEBRAFISH
The goal of this administrative supplement is to provide resources to extend the studies outlined in our parent grant R01 on the identification and the biology of miRNAs in the developing lung. A large number of studies now support a major role
MicroRNA-Mediated Gene Regulation in Lung Development
Oxidative modification of LDL is an important, if not obligatory, step that mediates the atherogenicity ofLDL. Many pathological conditions and environmental factors promote LDL oxidation, especially formation of early forms of oxidized LDL,ter
EARLY FORMS OF OXIDIZED LDL, TLRS AND ATHEROSCLEROSIS
This American Recovery and Reinvestment Act Administrative Summer Research Supplement proposes to increase the tempo of research activity in the associated R01 grant (R01 HL082662, An Autoimmune Basis for Pulmonary Hypertension) by hiring a Sci
An Autoimmune Basis for Pulmonary Hypertension
Microvascular growth (angiogenesis) and remodeling impacts many tissue repair processes in the postnatal organism and plays a critical role in a number of human diseases, including tumorgenesis, diabetes, and ischemic disorders of the lower lim
Arteriole/Venule Polarity in Adult Microvasculature
The goal of this supplement is to meet the objectives of the Recovery Act by enabling the hiring of additional staff, in order to accelerate the rate of progress in the areas of our existing RO1 grant that are currently showing the highest rele
The alveolar epithelium in lung injury and repair
The overall purpose of this Administrative Supplement to R01HL083151 is to: 1) Create an employment opportunity 2) Facilitate the reentry of a qualified scientist into active research 3) Accelerate the aims of the parent research grant. Specifi
Regulation of TGF-beta Receptor-dependent Vascular Disease
This ARRA project will provide crucial data directly contributing to validation of the central hypothesis of our parent R01 grant. These supplemental experiments will directly test our working hypothesis that the protein interaction domain
Role of P67phox in Myocardial Hypertrophy
Mitochondrial oxidative stress is associated with ischemia-reperfusion (I/R) injury. At the myocardial level of the post-ischemic heart, defective energy metabolism has been linked to marked overproduction of oxygen free radical(s). Available e
(ARRA) Myocardial injury associated with mitochondria-derived oxygen free radical(s)
Angiogenesis, the growth of new capillaries from pre-existing blood vessels, is tightly regulated by a number of vascular growth factors and their cognate receptor tyrosine kinases expressed on endothelial cells; principal among these factors i
Voltage-gated Nav channel Nav1.5 (encoded by SCN5A) initiates rapid depolarization of the cardiac action potential and is essential for normal cardiac conduction. Human SCN5A mutations may lead to cardiac arrhythmia and sudden death. Nav1.5 fun
Dysfunction in Ankyrin-based Pathways and Human Arrythmia
Boiselle, Phillip, Michael RESEARCH & RELATED Other Project Information 1. * Are Human Subjects Involved? l Yes m No 1.a. If YES to Human Subjects Is the IRB review Pending? l Yes m No IRB Approval Date: Exemption Number: 1 2 3 4 5 6 Human Subj
CT DIAGNOSIS OF TRACHEOMALACIA IN PATIENTS WITH COPD
The main goal of the proposed supplement is to examine the effect of Ate1 knockout on adhesion, migration, and contractility of major cell types relevant to cardiovascular development.  These studies will build on the results obtained in aim 3
Role of Protein Arginylation in Cardiovascular Development
Despite the success of lipid lowering drugs for the prevention of coronary artery disease and myocardial infarction, atherosclerosis remains the most common cause of disease-related death in the Western world and in developing countries. We and
This supplement to our project entitled 'Pericardial Fat and Subclinical and Clinical measures of Coronary Heart Disease' (R01 HL085323) aims to accelerate progress on understanding the relation between adiposity around the heart and deaths sec
Pericardial fat and subclinical and clinical measures of coronary heart disease
Beta-adrenergic receptor (beta-AR) stimulation is the primary mechanism to increase the contractility of the heart, however chronic beta-AR stimulation, as occurs in heart failure (HF), results in reduced contractility. In heart cells, beta-AR
Targeted Disruption of Beta-Adrenergic Signaling to Increase Cardiac Contractility
This administrative supplement will support a new postdoctoral fellow position to perform cutting-edge and novel fatty acid (FA) “pattern” investigation related to 5R01HL085710-03 “Fatty Acids and Major Cardiovascular Outcomes” to advan
Fatty Acids and Major Cardiovascular Outcomes
The purpose of the parent grant is to test the effects of a community intervention on smoke-free policy outcomes in rural underserved communities. The intervention combines assessment of community readiness with tailored, evidence-based dissemi
An Intervention for Promoting Smoke-free Policy in Rural Kentucky
The Duffy antigen, a minor blood group antigen, binds multiple chemokines with high affinity and is one potential modifier of lung and systemic inflammation located at tissue sites (endothelium) and in the vascular space (erythrocytes).  We hav
Duffy Antigen: Modifier of Systemic and Lung Chemokine Responses in Inflammation
This award provided research experience for an hispanic male for his first year after graduating from college before applying to graduate school.
Phase Response Curves for Home Remedies to Treat Circadian Misalignment
This award will provide funding for a postdoctoral candidate to support a project that examines whether telemedicine counseling that is delivered through physician offices is effective for smoking cessation among rural smokers.  This funding wi
Telemedicine for Smoking Cessation in Rural Primary Care
Numerous factors have contributed to the failure to produce a successful small diameter vascular graft. It is clear that a working graft must include a cellular component since inert materials are unable to interact appropriately with the surro
DEVELOPMENT AND ASSESSMENT OF A NATURAL BIO SCAFOLD FOR VASCULAR RECONSTRUCTION
DESCRIPTION (provided by applicant): Hypertension, or high blood pressure, is the most prevalent cardiovascular disease, afflicting nearly one in every three American adults. The prevalence of this disease is even higher in African-Americans bu
THE CARDIAC PROTEASE CORIN IN NATRIURETIC PEPTIDE PROCESSING AND HYPERTENSION
Award Description Spontaneously active embryonic stem cell derived cardiomyocytes could provide biological pacemaker that respond to neurohumoral stimulation and integrate indefinitely into the myocardium circumventing repetitive surgically inv
Embryonic Stem Derived Biological Pacemaker for the Heart
The period immediately following hospitalization is a vulnerable time for patients. After hospital discharge, approximately 40% of patients experience at least 1 serious medication error, a term that includes adverse drug events as well as pote
Pharmacist Intervention for Low Literacy in Cardiobascular Disease (PILL-CVD)
Funding to hire a new research assistant full time employee (FTE) would be invaluable in helping us accelerate the pace and expand the scope of research aims currently funded by my parent R01 grant that are focused on elucidating the role of ap
Role of apolipoprotein E4 in the progression and regression of atherosclerosis
Little is known about the pathogenesis of pulmonary arterial hypertension (PAH) and the factors that contribute to its higher prevalence in HlV-infected patients. Chronic exposure to viral products in the lung as well as HlV-induced immune dysr
Longitudinal studies of HIV-1 Nef in Pulmonary Hypertension
Principal Investigator/Program Director (Last, first, middle): Han, Zhe RESEARCH & RELATED Other Project Information 1. * Are Human Subjects Involved? m Yes l No 1.a. If YES to Human Subjects Is the IRB review Pending? m Yes m No IRB Approval D
A novel G protein signaling pathway controlling Drosophila cardiac morphogenesis
Our currently funded R01 grant is designed to elucidate the roles of STAT3 and SOCS3 signaling in acute lung injury (ALI) occuring after intrapulmonary deposition of IgG complex (IC) or LPS, and the underlying molecular mechanisms. In the first
STAT3 and its Acytalation in Acute Lung Injury
DESCRIPTION (provided by applicant): Asthma is a highly prevalent airway disease that is a major public health problem for which available treatment options are inadequate. Endogenous nitrated fatty acids (NFAs), thought to be produced from NO,
Nitrated Fatty Acids, Novel Anti-inflammatory Mediators in Allergic Airway Disease
.  The PI, Dr. Jun Ma, was qualified to receive the award as a New Investigator.  This supplement will provide salary support and supplies for Dr. Ayala for two years beginning August 1, 2009 and ending July 31, 2011.  Dr. Ayala is currently a
Can Diet-& Exercise-Induced Weight Loss Improve Asthma Control in Obese Adults?
The epicardium, an epithelial sheet of specialized mesothelium that covers the heart, is gaining recognition as an important source of signals and cells that modulate heart development and postnatal heart function. In the developing heart, epic
We propose to accelerate our progress on sub-aim D1b, ?Uncertainty of temporal assertions,? of the parent project, ?Discovering and Applying Knowledge in Clinical Databases.? The original sub-aim describes two approaches to handling uncertainty
Discovering and Applying Knowledge in Clinical Databases
Real time data collection and analysis would substantially strengthen public health surveillance at both regional and national levels. Although symptom and diagnostic data are stored in administrative health care databases, there currently are
Disease Surveillance in Real Time: Geotemporal Methods
[R01LM008443] is to test the hypotheses that use of the WEMR as an intervention can reduce: 1) the number of early stage Pressure Ulcers (PUs) that progress to Stage IV; and 2) the number of amputations resulting from Diabetic Foot ulcers (DFU
Diabetic Foot and Pressure Ulcer Databank
) we have been collecting, alterereinvolves  functional magnetic resonance imaging (MRI) of healthy elderly and depressed elderly individuals at 2 time points, 12 weeks apart. For the depressed subjects, the 2 time-points are just before starti
Altered Functioning of Cognitive and Affective Circuits in Late-Life Depression
This supplement is one of two linked applications from Florida State University and University of Michigan forming a collaborative R01 supplement in response to NOT-OD-09-056. We are recruiting toddlers with autism spectrum disorders (ASD) at a
1/2-Effects of Parent-Implemented Intervention for Toddlers with Autism Spectrum
The hippocampus is critically involved in flexible learning tasks, particularly in spatial navigation, reversal, and episodic-memory tasks and tasks that require planning and decision-making. In tasks with a spatial component, hippocampal cells
A hippocampal mechanism for considering possibilities
This proposal is to develop methods and instrumentation for the simultaneous imaging and optical stimulation of activity in large populations of neurons in the awake mouse brain under conditions in which the mouse is free to navigate in a virtu
IMAGING AND STIMULATION OF NEURAL ACTIVITY AT CELLULAR RESOLUTION IN AWAKE MICE T
Ten to 17% of children between the ages of 4 and 16 years meet the criteria for recurrent abdominal pain (RAP). Of these, up to 68% meet the criteria for irritable bowel syndrome (IBS), which also affects 15 – 20% of adults. Up to 66% of RAP
The diversity supplement to R01NR05352 has two primary goals: 1) To provide an opportunity for a post master s student interested in health related research to spend two years engaged in a mentored experience in scientific inquiry and to develo
INJURY FROM SEXUAL ASSAULT: ADDRESSING HEALTH DISPARITY
The long-term objective of this project is a better understanding of the role of genetic and environmental factors in human neuropsychiatric disorders through the study of the Gilles de la Tourette's syndrome (GTS), obsessive-compulsive disorde
This request for an Administrative supplement under the Recovery Act will generate a new position for a mid-career Research Associate who is an expert in Ca2+= imaging in glial cells. This hire will allow us to extend the originally proposed st
PROPERTIES AND FUNCTION OF GLIA ION CHANNELS
The conversion of adenosine to inosine (A-to-I) by RNA editing is a widespread RNA processing event by which genomically encoded sequences are altered through site-specific deamination of adenosine  residue(s) in precursor and mature mRNA trans
Necrotic neuronal death underlies the pathology of many neurodegenerative diseases and is an incapacitating outcome of stroke, ischemia, acidosis, and physical injury. Currently, there are no effective clinical treatments that protect against n
Mechanisms of Degenerative Cell Death in C. Elegans
Evaluation of work that has been completed: We have obtained TRIP8b heterozygous mice from KOMP. They have been removed from quarantine and we have now obtained the first litter, consisting of 2 homozygote KO males and 2 heterozygote females. O
Regulation of HCN channel trafficking and function in the brain by TRIP8b - administrative supplement
Small conductance Ca-activated K channels (SK channels) affect excitability and contribute to shaping excitatory postsynaptic potentials (EPSPs). SK2 channels are expressed throughout the dendritic arbors of hippocampal CA1 neurons and contribu
Molecular Physiology of the SK2 Channels in CA1 Neurons
Prion diseases are infectious, conformational neurodegenerative disorders characterized by the structural modicfication  of the prion protein, PrPC, into a pathological conformer, PrPSc.  Currently there is no effective therapy for this group o
Therapeutic Approaches for Prion Disease
With supplemental funds we will analyze gene expression of proteins of interest in dorsal root ganglia in parallel with the analyses of spinal cord samples from the same animals.  Changes in the neurochemistry of dorsal root ganglion neurons ha
Peptidergic Neurotransmission in the Spinal Cord
Aneurysmal subarachnoid hemorrhage (SAH) accounts for 5-10% of annual stroke cases. 50% of the patients die within 30 days with most deaths occurring within the first 48 hours. Acute brain injury after SAH is ischemic in nature and develops wit
MICROVASCULAR INJURY AFTER SUBARACHNOID HEMORRHAGE
This study seeks to determine the molecular basis of regulation of the JAK/STAT pathway in glial cells, to better understand the circuitry that goes awry in neuroinflammatory disorders such as Multiple Sclerosis.  One Specific Aim is proposed i
TRADD AS A REGULATOR OF CYTOKINE SIGNALING IN GLIA
The supplement will guide two summer interns to investigate the potential protective functions of QR2 electron donors on differentiated neuronal cells and crystallization of QR2 in complex with substrate analogs. The first project will focus on
Structure/Function Studies of Quinone Reductase 2
Glucocorticoids (GC) remain the mainstay of therapy for acute multiple sclerosis (MS) episodes. However, it is also clear that GC fail to prevent MS relapses and disease progression, and appear to have little effect on long-term T cell response
Steroid Resistance:  Experimental Autoimmune Encephalomyelitis/Multiple Sclerosis
Many drugs distribute poorly to brain and this is a central problem in drug development for the treatment of central nervous system (CNS) disorders, including brain cancer, stroke, ischemia, inflammation, infection, and neurodegenerative diseas
Role of plasma protein binding in brain drug delivery
Accumulation of pathogenic proteins and peptides with expanded polyglutamine repeats is characteristic of Huntington's disease (HD) and related neurodegenerative diseases, however precise molecular mechanisms that underlie pathogenesis remain e
Pathogenic Impact of SUMO Modification in Huntington's Disease
Functionally diverse proteins are generated by alternative splicing of primary transcripts in differentiating oligodendrocytes. PLP and DM20 are generated through the alternative selection of competing 5' splice sites in exon 3. As PLP becomes
PLP Alternative Splicing and Oligodendrocyte Differentiation
The goal of this proposal is to optimize engineered intracellular antibodies (intrabodies) as novel clinical reagents and drug discovery tools for the treatment of Huntington's Disease (HD), with broad, long-term relevance to other neurodegener
INTRABODIES AS NOVEL NEUROLOGICAL THERAPEUTICS
Myelination is essential for brain development and function but the precise mechanisms that control the development of myelinating oligodendrocytes are not known. In demyelinating diseases such as multiple sclerosis, the loss of myelin is also
ARRA: Extracellular Matrix Regulation of Myelination
This is a salary and fringe supplement to retain .5 FTE in support of research activities associated with the primary research award.  ):  Our recent work shows that glial restricted precursor cells (GRPs), grafted into a demyelinating or contu
Genetic approaches to functional remyellination after SCI
(Project summary)  This request for an administrative supplement is to support undergraduate research assistants on the main funded project.  The funding requested will support two named undergraduates during the summer of 2009, and two additio
LONGITUDINAL AXON GUIDANCE BY LONG RANGE CUES IN THE EMBRYONIC BRAIN
We propose to study a novel mechanism by which sensory neurons detect noxious stimuli. The ability to detect noxious stimuli is critical to survival, but can also be the source of unwanted pain. Injurious chemical, thermal and mechanical stimul
Glioblastoma multiforme (GBM) is the most advanced and invasive form of brain tumor. Various issues reduce long-term survival, the most common being recurrence even after treatment. GBM invasion and metastasis (dispersal) require the degradatio
Understanding and Preventing Tumor Dispersal with Hydrogel Therapeutics
The aim of the proposed research is to define how genetic loss of MeCP2, the gene responsible for Rett Syndrome (Rett), disrupts Brain Derived Neurotrophic Factor (BDNF) signaling in autonomic reflex pathways in the brainstem nucleus tractus so
This is a supplement to a currently active 5-year research project grant 5R01NS058659, which is in its second year. Summer support for a total of 7 students is provided:  3 high school students (1 during summer of 2009, and 2 during summer of 2
The modern view of cerebral cortical function ascribes a critical role for corticothalamic feedback in enabling the cerebral cortex to dynamically regulate its own input. However, the role of corticothalamic  (CT) circuitry remains a deep myste
Corticothalamic Neurons in Sensorimotor Cortex
This project aims to provide robotic therapy to subjects with hand/wrist/arm weakness after stroke.  The main focus is to examine predictors of treatment-induced gains in behavior.  We are exploring a range of traditional and non-traditiona
Title:  R01 NS060701 'Intra- and Inter-Neuronal viral Trafficking'.  Abstract and Specific Aims:  Supplemental funds provide support for one new full-time postdoctoral fellow.  The parent grant for this request has two main research objectives,
Intra- and Inter-Neuronal viral Trafficking
The Bamford laboratory investigates striatal synaptic plasticity using optical and electrophysiological experiments in murine models. The Bamford laboratory offers students and fellows a unique opportunity to determine how changes in striatal s
This project uses a portion of the federal funds to finalize a bus driver break area and public rest room building at the new SMART Central at Wilsonville Station multi-modal facility located adjacent to the WES Commuter Rail Station in Wilsonv
(a)  Construction of a Phase II Water Treatment Plant; (b) Construction of a Raw Water Intake Extension Pipeline; (c) Construction of a Regional Transmission Pipeline from a Water Treatment Plant to the Community of Poplar, and Wolf Piont and a
Construction of a Phase II Water Treatment Plant; Construction of a Raw Water Intake Extension Pipeline; Construction of a Regional Transmission Pipeline from a Water Treatment Plant to the Community of Poplar, and Project management and admini
Federal Workstudy provides need-based financial aid to students
Federal Work Study provides need basd financial aid to students.
Federal work study providing need based financial aid to students.
Federal Work-Study provides need-based financial aid to students through compensation for hours worked at on or off-campus jobs.
Federal work study provides need based financial aid to students
Federal College Work Study to provide aid to students
TECHNICAL & ADULT EDUCATION, GEORGIA DEPT OF
Col-20 Reconstruct Embankment SHOPP Roadway Preservation Grouped Project
Federal Work Study provides need-based financial aid to students
Federal Work Study provides need based aid to students.
CALIFORNIA STATE UNIVERSITY, DOMINGUEZ HILLS
Federal Work-Study provies need-based financial aid to students.
Federal Work-Study provides need based financial aid to students.
College Workstudy - Janet Lynn Iocono Principal Investigator
Federal Work-Study provides needs based aid to students.
Federal workstudy provides need-based financial aid to students
Federal work-study provides need-based financial aid to students.
Federal Work Study Provides need-based financial aid to students
Federal Work Study program provides part time jobs for students with financial need allowing them to earn money to help pay educational expenses.
Federal Work- Study provides need-based finacial aid to students through compensation for hours worked at on- or off-campus jobs.
Federal Work Study provides need based financial aid to students.
The Federal Work Study funds are used to provide part-time employment to Michigan Technological University students.  These funds provide need based financial assistance to students.
To provide part-time employment to eligible postsecondary students to help meet educational expenses and encourage students receiving program assistance to participate in community service activities.
Federal Work Study provides need based financial for students
ARRA enhancement to the Federal Work Study Program
FEDERAL WORK-STUDY PROVIDES NEED-BASED FINANACIAL AID TO STUDENTS.
BROOME COMMUNITY COLLEGE FOUNDATION, INC
Federal Work-Study provides need-based Financial Aid to Students.
Federal Wor-Study provides need-based financial aid to students.
The expectation is to provide an estimated 93 students the ability to work throughout the additional FWS funding for the 2009-2010 academic year.  This is an estimate due to the variance in the undergraduate and graduate level rate of pay and t
Federal Work-Study (FWS) Program - Provides funding for part-time employment to eligible postsecondary students receiving program assistance to participate in community service activities.
Federal Work-Study provides financial aid to students
Program Description   The FWS Program provides funds that are earned through part-time employment to assist students in financing the costs of postsecondary education. Students can receive FWS funds at approximately 3,400 participating postseco
Federal Workstudy provides need-based financial aid to students.
Federal Work Study provides needs based financial aid to students.
The Federal Work Study Program (FWS) provides funds that are earned through part-time employment to assist students in financing the costs of postsecondary education.
FEDERAL WORK-STUDY PROVIDES NEED BASED FINANCIAL AID TO STUDENTS.
Federal Work Study supports payments to individual students throughout the academic year.
Federal Work Study provides need-based financial aid
Quality improvement to playground area to provide a safer play environment having a direct impact upon development of children's cognitive, emotional, social and emotional, social and physical skills. Equipment Upgrade to separate play area for
Chehalis Tribe: Support youth center activities, develop outreach materials aimed at youth and parents.  Nisqually Tribe: Yert kit project designed to drawing in high-risk youth with positive alternative activities to gang involvement.  Shoalwa
Child Care/Youth and Elder Community Block Grant
Provide child care assistance to low income families while parents are working or participating in education or training programs.
ARRA Supplemental Funding for the Child Care and Development Fund (CCDF). Provide child care financial assistance to low-income working families and fund activities to improve the quality of child care.
FORT VALLEY STATE UNIVERSITY FOUNDATION, INC.
Renovations to FVSU Rural Business Outreach Institute's Entrepreneur Center (business incubator)
The purpose of the grant funds is to assist in the purchase of human patient simulators for the Allied Health Department of of the Heart of Georgia Technical College.  The project will support the development of small and emerging private busin
HOUSING AUTHORITY OF THE CITY OF MOUNT VERNON, THE
Conduct modernization activities at three Public Housing developments. Funfing can be expected to result in providing employment for architects and engineers, constructionworkers and product manufactures in US.In addition this funding can be ex
Renovation of Luther Wilson Homes, Nicholson Terrace, EJ Knight and Rivers Homes
HOUSING AUTHORITY OF THE CITY OF ATLANTA, GEORGIA, THE
The capital funds will be used to either renovate or demolish AHA public housing units. Renovation work will be focused on improving community safety, code compliance, viability of property, sustainability and improvements to the physical envir
The Housing Authority of the City of Brunswick is implementing the following activities using Capital Fund Recovery Act funding: 201 units of the AMP 2: Brooklyn Homes, Mercer Altama, Abbott Andrews (GA009000002) public housing development are
Re-face exterior of Brooklyn Homes and HVAC replacement at Mercer Altama and Abbott  Andrews
HOUSING AUTHORITY OF THE CITY OF MOULTRIE
We are removing trees that have damages sidewalks and are a trip hazard.  The landscape architect will provide plans for replacing trees.  Windows will be replaced with energy efficient windows.  The screen doors are old and unrepairable.  The
The award monies will be used to substantially modernize a family public housing development with the installation of HVAC units in each dwelling.  This funding is expected to provide employment for architects and engineers, construction worker
The Housing Authority of the City of Dublin is implementing the following activities using Capital Fund Recovery Act funding: in (GA069000100) Claxton Homes sewer line replacement is being done at Vinson Village Ext. and at Claton Homes 50 new
Public Housing Capital Fund Stimulus (Formula). This ARRA award is being used to modernize dwelling structures located at GA083-2, GA083-3, GA083-4, & GA083-5. The work includes replacing exterior doors/frames, converting two dwelling units to
Renovations and modernize 12 units located on Third Street, Lavonia, Ga. Site work and interiors.
AMP GA097000001:  1)  Roofing - Replace complete roofing systems at 23 public housing buildings to include all aluminum fascia and soffit and the addition of vinyl siding.  Gutter replacement will come in a future contract once all vinyl work i
Capital Funds for Low Income Public Housing Agency.  Work includes the renovation of bathrooms in 25 units of low income public housing and includes the installation of water-saving devices.
Renovation of Bathrooms at GA 110-1 and GA 110-2
install 50 energy eff energy star tankless hot water heaters
Conduct modernization activities including replacement of water and sewer systems.
HOUSING AUTHORITY OF THE CITY OF MILLIAN
ARRA capital fund grant for public housing
security fencing and site work at GA142000001P
Renovation of eight units, one maintenance facility, and site work
modernization of 50 public housing units with electric heat
HOUSING AUTHORITY OF THE CITY OF BUENA VISTA
Conduct modernization activities at Ables Homes development.  This funding can be expected to result in providing employment for architect, various craft skills, and product manufactures in the US.  Major renovation in four public housing units
Major Modifications To four dwelling units at Ables Homes.
HOUSING AUTHORITY OF THE CITY OF LITHONIA GEORGIA
HOUSING AUTHORITY OF THE CITY OF COLQUITT
Conduct modernization of Public Housing Communities.  This funding can be expected to result in providing employment for architectural, engineering and construction workers.
remove exisiting windows on Oakside Drive and replace with energy efficient security windows
Architect fees and Sundry cost to draw plans and specifications for work planned under ARRA funds: Screen Porches at Gause and Welborn Street. Kitchen cabinet upgrade for Rebecca Street and Gutter repair/replacement as necessary.
HOUSING AUTHORITY OF THE CITY OF CUTHBERT
This is a Public Housing Capital Fund Stimulus Formula ARRA grant.  It is for upgrading HVAC and electrical systems in thirty-three (33) units.
The Americans and Reinvestment Funds will be used in the modernization of 30 family units with HVAC systems.
American Reinvestment Recovery Act Funds for Housing Authority of Fulton County
Conduct modernization activities at various Public Housing developments. This funding can be expected to result in providing employment for architects and engineers, construction workers and product manufacturers. In addition this funding can b
Invest in public transportation. Cherokee County will use the 2009 ARRA funds to purchase a 5307 fixed route expansion vehicle. The 30' passenger vehicle will provide the opportunity to increase ridership and expand fixed route service to Chero
Invest in public transportation by purchasing additional buses including a hybrid and replacing a totally depreciated bus. Also fund maintenance costs including mechanics salaries and additional training. Also fund ADA expenses,salaries,trainin
ARRA Aug 3 repl bus/1 van/1 truck/misc expense
Installation of an Intergraded PV  & TPO Roofing system
ASSOCIATION OF AMERICAN GEOGRAPHERS, THE
Track 1: Departments and Underrepresented Students ALIGNED: Addressing Locally-tailored Information Infrastructure & Geoscience Needs for Enhancing Diversity.   The ALIGNED Project will support the development of knowledge-driven, place-based,
Opportunities for Enhancing Diversity in the Geosciences: ALIGNED Project
Glendale - Various Locations Citywide - Functionally Classified Roadways
DESCRIPTION (provided by applicant): Molecular machines, such as the ribosome or the nuclear pore, are of critical importance for the smooth functioning of the cell. This proposal deals with two issues that are important for the construction of
RIBOSOMAL GENES OF YEAST AND THEIR REGULATION
DESCRIPTION (provided by applicant): It would be potentially advantageous if organs could be repopulated from a small number of cells that would remove and replace other cells during growth, preserving tissue dimensions during the replacement.
DEVELOPMENTAL REGULATION OF GROWTH, SIZE AND SHAPE
DESCRIPTION (provided by applicant): Kinesins comprise a diverse superfamily of over one hundred different proteins, all containing a highly conserved globular catalytic domain with ATPase and microtubule binding activities. Despite the high de
STRUCTURAL BASIS OF KINESIN MOTOR MOVEMENT
Gila River Indian Community - Various Locations - Functionally Classified Roadways
Big South Fork National River and recreation Area PMIS 152731. Environmental Assessment and Wetland delineation for the closure of 53 Hazardous Abandoned Oil and Gas Wells.
Office of Policy, Management and Budget/Chief Financial Officer
Department of Interior (DOI) American Recovery and Reinvestment Act (ARRA) Program ManagementT Support (Phase 1) Assess and make recommendations for the implementation and management of the Department of Interior ARRA program at a bureau level,
TISHMAN CONSTRUCTION CORPORATION OF D.C.
The goal of the base contract work is to improve the energy efficiency of federal buildings and minimize their environmental impact through the retro-commissioning/re-commissioning process. Building systems are evaluated to verify if they are o
Construction Management (Agency) Services for Construction of new federal Courthouse in Billings, Montana. Project will provide Construction Management (CM) Services to assist in development of a solicitation for Design-Build project for a new
Condition Assessment of (15) Fresco Murals by Cook.  Located in U.S. Post Office and Courthouse, San Antonio, Texas prior to construction in the facility.  Based on our assessment and understanding of the construction project, guidelines for ar
Engineering and Commissioning expertise to conduct re-commissioning / retro-commissioning planning, identify energy and water conservation, scoping, testing, investigation, evaluation, analysis, calculations, recommendations, and report writing
The goal of this activity is to provide a needed augmentation to the simulation capacity, data storage capacity, and visualization capability in support of the climate and weather simulation communities in NASA. This activity will increase the
M.C. Smith Federal Building. Schematic design for all discipline for building shell & core and tenant spaces for the building.     Design excellence program concept design related to a new building entry, security screening, physical security,
Change order work associated with construction of New Land Port of Entry
The scope of work is focused on building systems affecting energy use and indoor environment, including shell infiltration and heat loss for the Moakley Federal Courthouse loacted in Boston, MA.
11th Floor renovation at the TP O'Neil Federal Building.
The Thurgood Marshall Courthouse infrastructure upgrade.
Recipient has been retained by the United States General Services Administration to analyze and design a solution to a chronic water-leakage problem existing at the Jacob K Javitz Federal Building located in Downtown Manhattan.  Specifically, t
EIP - Alpine Co to Route 50 ('Project Name' not listed in TRPA FTIP; SHOPP Lump Sum - Mandates
Project will remedy Maintenance & Improvement (M&I) deficiencies at the Tribe's Health Clinic.
Federal project P182029, involving grading, draining, milling plant mix, placing crushed base and  bituminous pavement surfacing, concrete box culvert, removal and replacement of cattle guards, deer  fencing, and miscellaneous work on 4.45 mile
This was an NCRR ARRA Supplement for Translational Research to the COBRE on Membrane Protein Production and Characterization.  It supported the establishment of a new research program in neurodegenerative diseases by David Colby, Ph.D.
COBRE: Membrane Protein Production and Characterization
This project is the Delaware portion of a regional effort from the Northeast IDeA states (VT, NH, ME, RI and DE) to provide the first fiber-optic backbone through northern New England that connects higher education and biomedical research insti
The Delaware INBRE, a statewide collaboration among 5 Delaware academic and clinical institutions, was renewed in April 2009 for another five years. The biomedical focus of the Delaware INBRE is on cancer, neurosciences and cardiovascular resea
Our hypothesis is that by expanding our nascent Neuro-Oncology research program, we will form a Core that will lead to a better understanding the biology of pediatric brain tumors.  We will use funds from this P30 to recruit and support new ass
Grant name:  Novel small-molecule therapies for CF (Supplement). The purpose of this project is to develop and apply a high-throughput screening assay to identify small-molecule inhibitors and disrupters of Pseudomonas biofilms.  The goal is to
GRANT NAME:  SCOR on Lower Urinary Tract Function in Women  AWARD DESCRIPTION:   Purpose This study is designed to assess whether markers of oxidative stress are associated with incontinence in patients with type 2 diabetes and to test the hypo
SCOR on Lower Urinary Tract Function in Women
Tree landscaping and miscellaneous work on 4.3 miles on US 20/26/87 beginning at RM 135.91 and ending at RM 139.21 in the City of Douglas in Converse County.
This award will make it possible to modify existing public housing dwelling units at this site to make them fully accessible with UFAS standards. The scope of work for these units will include, but not necessarly be limited to, new kitchens, ca
MCKEESPORT HOUSING AUTHORITY OF THE CITY OF
Amercian Recovery and Reinvestment Act of 2009 Distributed through the Capital Fund Program
Conduct interior renovations to 90 apartments at the Marvine family development, including kitchens, bathrooms, doors, windows, electrical and painting.
HUD Public Housing Capita Grant ARRA Funds.  These monies are being used to fund improvements to the public housing buildings and units in Tioga County PA.  These improvements include improvements in many areas including increases in efficiency
ARRA Public Housing Capital Grant Improvement Plan per HUD form 500075.1  Submitted to and approved by the Philadelphia HUD office.
Conduct modernization activities at our housing development. This funding can be expected to result in providing employment for architects & engineers, construction workers, & product manufacturers. In addition, this funding can be expected to
This project will consist of replacementof approximately 80 energy efficient grade windows.
American Recovery & Reinvestment Act (ARRA)
HOUSING AUTHORITY OF THE COUNTY OF BEAVER
FUNDING FOR MODERNIZATION ACTIVITIES AT STEPHEN PHILLIPS HOMES. JOB CREATION CAN BE EXPECTED FOR ARCHITECTS, ENGINEERS, CARPENTERS, PLUMBERS, ELECTRICIANS, PAINTERS, AND PRODUCT MANUFACTURERS IN ADDITION TO SUBSTANTIALLY IMPROVING THE QUALITY O
PUBLIC HOUSING CAPITAL FUND STIMULUS(FORMULA) RECOVERY ACT FUNDED
Combine CFRG funds with FY 2008 Capital Fund Program to convert 4 existing units to 2 H/C accessible units; equip 1 unit with A/V aids; provide van accessible parking
New windows for family units. New furnaces for family units. Pave street.  Widen sidewalk in park to make handicap accessible.
Public Housing Capital Fund Stimulus (Formula) recovery
Replacement of windows in a seven story high-rise and window/sliding door replacement in townhouse family development with energy star rated windows/doors  New roof installation on four buildings at the townhouse family development
Rehabilitation and expansion of the parking facilities for the Elizabethtown Train Station - Keystone Corridor.
BERKS AREA READING TRANSPORTATION AUTHORITY
Invest in public transportation by purchasing four new hybrid-electric buses, four new hybrid-electric paratransit vans, three new diesel paratransit vans, installation of surveillance and security equipment on 25 transit vehicles, and renovati
Purchase 11 buses, security equipment and facility improvements.
These funds were awarded to purchase three Fixed Route vehicles for the County of Lebanon Transit Authority. We are using these funds to purchase one 29' low floor bus and two 40' low floor buses.
INDIANA COUNTY COMMUNITY ACTION PROGRAM INC
Loan for property acquisition and related office construction.
Beardsley Rd Connection: Loop 101 (Agua Fria Fwy) to Beardsley Rd at 83rd Av/Lake Pleasant Pkwy
Connect 28 Houses in Spider Mound to Jeddito Water Transmission Main.
Indian Health Services approved ARRA supplemental funding for the construction of one new secure solid waste transfer station to serve the community.
Solid Waste Station, Phase II Fort McDowell Yavapai Nation
Various Locations  (Central Area) - Functionally Classified Roadways - Phoenix
The proposed research program will promote general interest in science while advancing discovery. This REU proposal focuses on research participation of students of all of preparation.  Proposed collaborative effort between different department
REU SITE: RESEARCH EXPERIENCE FOR UNDERGRADUATES IN ASTROPHYISICS, NUCLEAR AND PARTICLE PHYSICS
Explore classical stability properties of topological black holes and black holes in topologically massive gravity.
Probing Fundamental Physics on Cosmological Scales
This grant is to support a continuing program of nuclear physics measurements using neutron interferometry. Unlike a scattering experiment which measures a cross section, the neutron interferometer detects a neutron phase shift with an accuracy
Collaborative Research: Neutron Interferometry Experiments for Nuclear Physics
The main goal is to model physical properties of so-called compact stars, which are the collapsed cores---about 20 kilometers in diameter but with the mass of the Sun---of ordinary stars that have exhausted their nuclear fuel. Like the Earth, a
Modeling Multi-fluid Gravitational Dynamics of Compact Stars with Quark Matter Cores
Beyond LambdaCDM: Theoretical Predictions & Observational Constraints:  Recent advances cosmology lead to a coherent picture of the standard model of Big Bang inflation. We are now in a position to ask more fundamental questions such as: 1)why
Beyond LambdaCDM: Theoretical Predictions & Observational Constraints
Collaborative Research: Community Infrastructure for General Relativistic MHD (CIGR)
This award supports experimental research investigating quantum information using nuclear spin.  In quantum information research, atomic gases have been successfully used in many important applications.  Prior experiments using atomic ensembles
Atomic Ensemble Quantum Information with Nuclear Spin
This collaborative proposal seeks to provide a coordinated learning and research experience for Ph.D. students from seven universities that have developed different experimental and theoretical/simulations capabilities and have established a re
Collaborative Research: Graduate Student Teaching Through Research on Plasma-Based Accelerators
The Tulalip Automatic Water Meter System project was awarded through the American Recovery and Reinvestment Act.  A total of $663,420 is available through this grant funding to achieve improvements in water systems at the Tulalip Indian Reserva
FEDERAL WORK STUDY PROVIDES NEED BASED FINANCIAL AID TO STUDENTS
CONFEDERATED TRIBES OF GRAND RONDE INDIANS,THE
I.H.S. ARRA Maintenance & Improvement Funding.  Funding for renovation of the Grand Ronde Health & Wellness Center including roof (44,400 sq ft), HVAC (42 units), carpet (18,400 sq. ft.) and lobby access and confidentiality improvements.
Grand Ronde Health and Wellness Center Renovation Project
Federal Work-Study provides need based financial aid to students
FEDERAL WORK-STUDY PROVIDES NEED-BASED FINANCIAL AID TO STUDENTS.
MARICOPA COUNTY COMMUNITY COLLEGE DISTRICT
VENTURA COUNTY COMMUNITY COLLEGE DISTRICT
BOARD OF TRUST OF COMMUNITY TECHNICAL COLLEGE
BOARD OF TRUSTEES, ST PETERSBURG COLLEGE
Federal work-study need-based financial aid to students.   NOTE:4/15/10 Ticket#382058. Clicked final report for Jan2010 submission;money was completely spent.
Board of Trustees, St Petersburg College
Federal Work_Study supports payments to individual students throughout the academic year
Federal Work-Study provides need-based financial aid to students. The award supports payments to individual students throughout the academic year.
Federal Work-Study Provides need based finanical aid to students.
MINNESOTA STATE COLLEGES AND UNIVERSITIES
Federal WorkStudy provides need-based financial aid to students.
Federal Work Study provides need -based aid to students
Federal Workstudy provides need based financial aid to students.
Federal Work-Study: Provides need based financial aid to students.
Federal work study provides need-based financial aid to students
POLYTECHNIC INSTITUTE OF NEW YORK UNIVERSITY
FEDERAL WORK-STUDY PROVIDES NEED-BASED FINANCIAL AID TO STUDENTS
AUSTIN, STEPHEN F STATE UNIVERSITY (INC)
Federal Work Study provides need-based financial aid to students. Funds exhausted. Award still active.
Federal Work-Study provides need based finanical aid to students
Federal Worl-Study provides need based financial aid to students
This contract is a for Architectural/Engineering services for the design of a federal employee parking garage and a master plan for the San Juan, PR Federal Bureau of Investigations Field Office Consolidation project.  The project as a whole wi
The purpose of this scope of work is to assist GSA by providing the Construction Mangement as Agent (CMa) Services necessary for pre-award, procurement, design, construction and commissioning phase services for the Huntington, WV Federal Buildi
TAS::47 4543::TAS.  CONSTRUCTION MANAGEMENT AS AGENT SERVICES THROUGH THE PROCUREMENT AND DESIGN PHASES.  THIS WORK IS IN SUPPORT OF THE MODERNIZATION PROJECT AT THE RICHARD POFF FEDERAL BUILDING IN ROANOKE, VA. Construction management, move co
Poff Federal Building in Roanoke, VA - Energy Renovation, A/E Study
The objective of this project is to renovate existing bathrooms located in the 1st, 2nd, 3rd and 6th floor of the Annex building.  The renovation will include the installation of energy efficient plumbing and electrical fixtures to meet the Fed
Comprehensive interior /exterior rehabilitation of the Robert S. Vance Fed. Bldg. and Courthouse located at 1800 5th Avenue North in Birmingham, AL.    The Scope Of Work for the Project is based upon the following documents: 1. ?Architect-Engin
Construction Management Services for Judges' Swing Space at Samuel M. Gibbons Federal Courthouse The purpose of this scope of work is to provide GSA guidance and direction as the Construction Manager as Advisor (CMa) Contractor who will be the
This project is the second phase of the water intrusion repairs for the Sam M. Gibbons United States Courthouse, which includes the following activities.  On the west elevation, floors 1-5, we will be repairing the curtainwall windows, curtainw
Architect-Engineer Services, Madison, Wisconsin High Performance Green Building at the Kastenmeier U.S. Courthouse
Design services, Post Construction Award Contract Services, Record Docs and Construction Inspection Services for recommissioning and building tuneup for the ARRA project at Stokes Federal Building
The objective of this work order is to achieve the re-commissioning and retro-commissioning goals set forth in the ARRA (American Recovery and Re-investment Act) for the Howard M. Metzenbaum USCH (United states Court House) Cleveland, Ohio by c
Provide architectural and engineering services for ARRA energy and water conservation measures.  Work includes meetings, site visits, calculations, reports, drawings and construction estimates. Provide art conservator services for existing wall
This award supports the upgrades to the lighting and building automation systems at the Federal Building and U.S. Courthouse in Ann Arbor, Michigan by providing construction documents, submittal review and record documents.  The upgrades to the
The primary purpose of this project is to install an array of solar panels on the roof of the Major General Emmett J. Bean Center Indianapolis, IN 46249.  The goal is to install the most energy-efficient systems available and to reduce the buil
This lighting study is being prepared to serve as a basis for design recommendations for the replacement of the existing lighting system which will provide improved lighting control and energy efficiency. The subject of the study is the Ground
Provide architectural and engineering services  for the modernization of the Whipple Building at Fort Snelling, Minnesota.  The building has over 617,000 gross square feet. The facility has a basement, ground level and first through sixth floor
Machine Tool (Metal Cutting Types) Manufacturing
ALLEY POYNER MACCHIETTO ARCHITECTURE, P.C.
Pre-design to install roof photovoltaic system.
A Pre-design study was completed to evaluate a 'retro-commissioning' report prepared by Teng Associates.  This study summarized possible energy conservation and monitoring measures to be implemented at the Neal Smith Federal Building in Des Moi
This work order was a follow-on to a previous work order and is for pre-design development, additional site investigation and design services for replacement of the basement Air Handling Units, outdoor air intake threat mitigation and basin hea
The Architect/Engineer is required to participate in the Commissioning Kick-Off Meeting, and review, provide written commentary, and participate in on site review meetings for both the 'Go/No Go Analysis' and the 'Energy Management Control Syst
GOODFELLOW SANITARY AND STORM SEWER PROJECT - The Federal Center at Goodfellow sanitary and storm system is to be separated and reconstructed to meet local Metropolitan Sewer District (MSD) drainage regulations. Underground detention facilities
During the Preconstruction Phase, obtain information from the Government database and perform the following tasks: a) Attend and be prepared to comment on bi-weekly design meetings (every two weeks) starting in Mid Sep. 2009 through Feb. 2010.
Retro-commissioning Services for Robert V. Denney Federal Building (Lincoln, NE) along with investigating the existing Energy Management Controls System and Advanced Metering Systems for the Robert V. Denney Federal Building and U.S. Courthouse
Remove and replace approximately 13,000 square feet of bituminous built-up roofing, add new insulation to create an R-50 insulation value when complete, and install architectural metal at all parapet and coping locations.  The project shall inc
Wind Tunnel Testing Structural Study for the Micky Leland FOB  (TX0298ZZ located at 1919 Smith Street, Houston, TX 77002). Provide engineering testing and analysis services for the site, as well as, to determine building cladding design loads.
MOD12 - Contract Administration for Renovation of San Antonio Post Office & Courthouse  MOD14 - Design of temporary space for tenants who must move during selected construction phases. Also, design for lease space for four new tenants moving in
This is a 237,000 square feet United States Courthouse Austin Texas.  We have had a very successful preconstruction phase of work and see no reason why will not have a great construction project with a successful completion.  We have completed
Construction contract for remodel of Post Office/Courthouse located in San Antonio, Texas.
Recommissioning/retro-commissioning of the Byron White Courthouse with the objective of reducing energy consumption to the greatest extent possible within the funding limitation. Deliverables will be a list of Energy Conservation Measures recom
Design study with a scalable range of power delivery along with a transformer design specification for the construction of a new Tier III data center facility at Denver Federal Center
Perform the demolition design, asbestos abatement design, asbestos abatement and demolition of the existing Montana-Dakota Utilities building and the former TCFB Twin Cities Federal Bank buildings, in Billings, Montana.  Deliverables to include
'PS58 - Scope of work includes demolition, removal, and disposal of existing Heating, Ventilation and Air Conditioning ductwork, installation and appunenances on Floors 5, 6, 8, 1 South and Passenger Elevator Lobbies in conjunction with the ''R
SUPPLY NECESSARY MATERIAL, LABOR AND SUPERVISION TO REPLACE THE EXISTING PLEXY GLASS WINDOWS WITH NEW TEMPER GLASS ON THE 1ST FLOOR AT 230 N. 1ST AVE. PHOENIX, AZ 85003
Construction Management Services for Federal Courthouse in Bakersfield, CA.
Asbestos and lead abatement monitoring of the removal of the air handling system (ducts) of the three and a half remaining floors (5,6,8,and half of the 1st) of the Federal Building at 300 N. Los Angeles St. Los Angeles Ca. This includes the el
The Award is for Construction Manager as Agent (CMa) to provide oversight and support in the management of the modernization and renovation effort at the Robert Smith Vance Federal Building and United States Courthouse in Birmingham, Alabama. A
Review PER for the Drinking water porject for town in accordance with the Rural Development Bulletin 1780-2 and Utah supplement included with the projects.  The PER being reviewed defines the project for Water and Environmental Program funding.
Services of individuals to assist in coordination of collection, analysis, and reporting of international research & training activities funded under the ARRA.
For the construction of the new Land Port of Entry (LOPE) in Blaine, Washington in order to construct a portion of the facility (new administration building) GSA had to remove an existing 2 lane interstate and construct a new bridge.  The bridg
The purpose of the award is to Modernize Wing 2 of the Departement of the Interior Main Interior Building.  Construction activity is anticipated to start March 15, 2010.  The delivery date for all occupied areas and supporting Mechanical, Elect
1. EXERCISE OPTION 1, PHASE 2 ? Construction services in the amount of $34,914,000.00. 2. EXERCISE OPTION 1, PHASE 2, ALTERNATE No. 7 ? Blast Windows in the amount of $1,400,000.00. 3. Provide all labor, materials and equipment for additional s
Design, LEED, and construction administration services for Renovations to the Department of the Interior relating to the following areas:  1.)  Replacement Bollard System  2.)  Lessons Learned Bulletin for Series 3 Drawings  3.)  Exterior Faça
Retro-commissioning study of Federal buildings in Auburn Washington and Anchorage Alaska
Provide Retro Commissioning services at the specificed locations - Albuquerque, NM; Gallup, NM; Las Cruces, NM; and Santa Fe, NM
RECOVERY. CONSTRUCTION MANAGEMENT SERVICES FOR ROAD REHABILITATION, PHASE 1, SHENANDOAH NATIONAL PARK, VIRGINIA.
Apprisal and Market Valuation of 9.93± acre, vacant industrial site located at 9851-9917 Via de la Amistad, Otay Mesa, San Diego County, California. This property is immediately adjacent to the existing commercial border crossing facility iden
This contract is in support of the Recovery and Reinvestment Act of 2009.  The contractor will provide support services to the OCFO Customer Service Branch (CSB), Finance, Accounting, and Analysis Division (FAAD), for processing pre-award and p
NATIONAL COLLEGE OF BUSINESS AND TECHNOLOGY, INC.
Award was to produce and deliver 285,120 pounds of roasted unsalted 12/16oz peanuts. Product was delivered to TEFAP locations in the following states - DC, SC, FL, NY, MI, TX, MS.
Roasted Nuts and Peanut Butter Manufacturing
Investment in public transportation by purchasing 40 replacement hybrid units, 40-foot length, heavy duty low floor hybrid buses for fixed route service in the San Juan Metropolitan Area.
ARRA - Acquisition of  40 hybrid replacement buses.
#37 Ave de Diego San Fransisco, Monacillo Ward
THIS APPLICATION IS FUNDED AS FOLLOWS: 2009 TRANSIT CAPITAL ASSISTANCE GRANTS - URBANIZED AREA FUNDING PROGRAM. THIS GRAN APPLIES THE 2009 ARRA ALLOCATION OF $185,500.00 FOR ONE BUS EXPANSION. WE WILL PURCHASE ONE TROLLEY WITH 30' MEDIUM DUTY T
2009 TRANSIT ASSISTANCE GRANTS - URBANIZED AREA FUNDING PROGRAM
HIGHWAY & TRANSPORTATION AUTHORITY, PUERTO RICO
Invest in Public Transportation by Purchasing of Four (4) Trolleys, Four (4) Paratransit Vans and the Engineering, Design, Acquisition and Instalation of 20 Passenger Shelters.  Naguabo - Paratransit vehicles were delivered to the municipality
Purchasing of Four (4) Trolleys, Four (4) Paratransit Vans and the Engineering, Design, Acquisition and Instalation of 20 Passenger Shelters.
Roberto Sánchez Vilella Governmental Center
Invest in public transportation by replacement of conventional petroleum dependent energy/security lighting with a photovoltaic solar system in FTA funded vehicle maintenance and storage facilities
Renewable Energy/Retrofit Solar Lgt & Sec
Invest in public transportation by reconstructing a ferry terminal, purchasing equipment for ferry boats, and performing preventive maintenance to ferry boats and terminals.
Reconstruction of the Fajardo Ferry Terminal, New Ticketing Building, purchase of equipment for the Fajardo ferry boats, and preventive maintenance for the Fajardo ferry boats and terminal
Use of ARRA funds to purchase two minibuses, make deferred maintenance improvements to Public Transportation Terminal and administration of grant program. The project includes:
Acquisition of Two Minibuses and Maintenance Improvements to Public Transportation Terminals
Basic in-home digital converter box, antenna, and scanning assistance to those who have not been able to successfully complete the digital transition on their own.
DTV Expert Installs Southeast Region 4 covering the state of Georgia (Atlanta Metropolitan area and surrounding areas). Primary objective was to complete 1000 expert installs of the DTV converter boxes and funding was extended to include an add
Basic Installation and support of digital Television converter boxes.
Basic In-home Digital converter box installation in AL, FL, GA, MS, NC, SC, TN and VA. Installed 5,317 boxes.
Southwest Region (TX, OK, LA, NM, AR, PR)
Expect , In-Home Digital Transitions Service. Expert installation of Digital Conventer Boxes in homes to during transition from analog to digital television broadcast.
We operated 4 static full service Digital Television (DTV) Walk in centers and 6 DTV mobile clinics in Puerto Rico Region 3 (San Juan, Ponce). Established procedures to locate, operate, and close-out the walk in center and 6 mobile centers with
Pacific Region (OR, WA, ID UT, CA, AK, NV, AZ)
Basic In-home Digital converter box installation in CT, DC, DE, MA, MD, ME, NH, NJ, NY, PA, RI and VT. Installed 8,756 boxes.
planting 73 trees at pea ridge military park
Flower, Nursery Stock, and Florists' Supplies Merchant Wholesalers
'Rapid progress in understanding the epidemiology and molecular virology of human caliciviruses (HuCVs) in the past decade has highlighted the importance of HuCVs as a cause of acute gastroenteritis. The recent finding that Noroviruses (NVs) re
Malaria continues to be a global health problem killing 1-2 million people each year. Because of prevalence drug resistance it is urgent to identify new therapeutics for treatment. However, the development of new drugs by traditional screening
Eosinophilic esophagitis (EE) is an emerging entity throughout the world, as documented by the recent case series from the developed countries including USA. Despite the increased incidence of EE there is limited information regarding its under
Role of IL-15 in the Pathogensis of Eosinophilic Esophagitis
We seek to integrate our molecular investigations with other clinical and pathologic outcome variables that are important in pediatric EE. In Aim 1, we will develop a local internet based registry of subjects with EE to capture defined clinical
Understanding the genetic basis of human disease is one of the most important problems in biomedical research.  Most genetic polymorphisms have no relevant functional effect, but determining deleterious from benign changes has been challenging.
Impact of Genetic Variation on Folate Metabolism:  Etiology of Neural Tube Defects
The overall purpose of this supplement is to create a new position in our laboratory for a postdoctoral research fellow, thus accelerating the tempo of our research and promoting new job creation.  Research supported by HL-091769 is defining im
An Animal Model of Hemophagocytic Lymphohistiocytosis
The Aims of the project are:  1.  Determine if Notch signaling regulates semilunar valve cell lineage differentiation and leaflet stratification in vivo.  2.  Dissect the Notch signaling pathway and intersecting pathways in aortic valve progeni
Notch signaling in heart valve development and disease
This contract will test the following 3 hypotheses:  1. IL-4 and IL-13 induction of AHR is completely accounted for by its effects on smooth muscle and epithelial cells.  2. Induction of airway remodeling by IL-4 and IL-13 is primarily accounte
Direct IL-4 and IL-13 effects on pulmonary smooth muscle in allergic airway disease
Myelination allows rapid propagation of action potentials in the nervous system. Dys- and demyelinating disorders are among the most common neurological pathologies affecting young adults. Myelinating glial cells such as Schwann cells (SCs) of
MECHANISMS MODULATING CYTOSKELETAL DYNAMICS DURING SCHWANN CELL MYELINATION
Aging is the single largest risk factor for disease in developed countries. The ongoing demographic change in the American population is greatly increasing the proportion of the population at risk for socially and economically important age-rel
Grant Name: Mechanism of Pseudomonas-mediated epithelial cell damage Pseudomonas aeruginosa (PA) is one of the most virulent opportunistic pathogens of man. The morbidity of PA infections results from the ability of the bacterium to colonize pr
Mechanism of Pseudomonas-mediated epithelial cell damage
Genetic and Molecular Epidemiology of Adult Glioma: The purpose of the project is to accelerate progress on our studies of well characterized individual, genomic, and tumor information regarding glioblastoma and other high grade gliomas from a
Genetic and Molecular Epidemiology of Adult Glioma
This is the final report for this award. The project is complete, but the research expense did not exhaust the funds awarded. Closeout documents have been submitted to NCI for processing the remainder of the award that is being returned to NIH.
Role of metalloproteinases in mammary gland remodeling
Glioma is a rapidly fatal brain cancer, featuring immunosuppression and abnormal angiogenesis. The project will accelerate progress on studies of immune and angiogenesis markers as predictors of survival in well characterized glioma patients an
Biomarkers of survival in glioma epidemiology
In this proposal, we used advanced magnetic resonance imaging (MRI) technology to visualize the trafficking of cellular immunotherapy against colorectal cancer.  Most often applied to advanced cancer, where existing therapies have limited effic
CLINICAL TRANSLATION OF 19F MRI TO VISUALIZE CANCER IMMUNOTHERAPEUTIC CELLS
Approximately 8% of children in the United States are diagnosed with Specific Language Impairment (SLI). In addition to problems acquiring morphology and syntax, a significant number of children also demonstrate difficulty acquiring vocabulary.
Treatment of Lexical Deficits in Young Children with SLI
Grant Number: Grant Number: 3R01DE016849-04S1 Project Title: DENTIN STRUCTURE, DEMINERALIZATION AND REMINERALIZATION.  The ARRA supplement allowed us to hire additional personnel (post-doc or Research Associate) at UCSF to accelerate work on po
Dentin Structure, Demineralization and Remineralization
The goal of this project is to develop new, improved metabolic MRI imaging methods and translate them to be applicable for future human patient studies. This project is based on a recently invented method for providing real time metabolic imagi
Technique Development for Hyperpolarized C13 MR Studies
This study addresses the growth of PC12 cells in vitro and observation of neurite grown after infecting the cells with HSV mutant strains. This project was completed during summer 2009.
Genetic analysis of Herpes virus neurotropism and enceph
Funds were used to purchase equipment and materials used for quantitative measurement of NHE1 activity and microscopic imaging of the localization of NHE1 and NHE1-regulated and -associated proteins in cells.
Mechanisms of Receptor Regulated Na+-H+ Exchange
Grant Name: Can drug aggregation affect physiologic distribution? (Supplement to GM71630).  The key goal was to test whether drugs form colloidal aggregates in the intestine, and whether this affects their distribution.  This was to be investig
A Specific Mechanism for Non-Specific Inhibition
Our group focuses on understanding how amino acid substitutions disrupt molecular functions that cause human disease. In our currently funded R01, we are developing methods we call in silico functional profiling. This method works by learning r
Informatic profiling of clinically relevant mutation
Peripheral arterial disease (PAD) is an understudied debilitating chronic illness that is most prevalent in the elderly. Patients with PAD experience substantial walking impairment, due to symptoms of limb ischemia (claudication) that significa
Multifactor Risk Reduction for Optimal Management in Per
The goal of this grant is to explore the role of gap junctions in regulating neural stem and progenitor cell proliferation and neuronal migration.  Recently, we expanded our goals to study gap junction regulation of microcircuit formation.  Our
The Physiology of Radial Units in Corticogenesis
Our laboratory is studying the neural circuitry of the brain. We attempt to generate disease-like states in a model organism, the zebrafish, which can be investigated with genetic methods and microscopy. The long-term goal is to better diagnose
Genetic Tools for the Analysis of Nervous System Functio
Stroke is a major cause of death and disability in the elderly.  However, in vivo experimental stroke studies, including the evaluation of neuroprotective and cell replacement strategies, have relied almost universally on models of stroke in yo
Functional contribution of neural stem cells in stroke
The principal goal of this grant is to determine whether neonatal seizures disrupt the integration of hippocampal granule cells in the developing brain.  This study involves exposing seven-day-old transgenic Gli1-CreERT2 X GFP reporter mice to
Short and long-term impact of neonatal seizures on hippocampal granule cell integ
Visual Casual Models in Clinical Explanation
Recovery Act 2009 Main Canal Piping and Ponderosa Hydroplant Project: This project is to pipe the remaining .75 miles of Swalley 's Main canal; complete the construction of  a.75 MW hydropower plant;and develop/instrall SCADA controls and telem
Recovery Act 2009 Main Canal Piping Project and Ponderosa Hydropower Project
The Lower Tule River Irrigation District's Tule River Intertie Project will help keep several people employed in the private and public sectors of Tulare County where unemployment is now over 16 percent.  The stimulus package funds made availab
Roza Diversion Dam Roller Gate Replacement
The Bureau of Reclamation contracted labor for hand-planting of wetland plants at the Imperial Ponds Conservation Area (Imperial National Wildlife Refuge, Arizona). Reclamation and the US Fish and Wildlife Service are working cooperatively to c
The long-term goal of our research is to make feasible the clinical translation of experimental fetal cardiac surgery, i.e., open-heart surgery in utero, for babies affected with the most severe congenital heart defects.  Despite continuing eff
Mechanism of Vasopressin-Mediated Placental Vascular Resistance after Fetal Bypass.
This Recovery Act supplement award supported one undergraduate student to work on part of aim 1 of the parent R21 grant for 10 weeks from May to August 2009. Recruitment of the summer student was done through the highly competitive Cincinnati C
Novel Model of Adult Lung Epithelial Stem Cell Expansion
The proposed research focuses on innovative, preclinical therapies for the variants of Gaucher disease, a rare, but not uncommon, inborn error of metabolism. The proposed studies use our unique mouse models of Gaucher disease to address the hyp
Therapy of Gaucher Disease:  In Vivo Enhancement of Residual Mutant Activity
This project will develop a model for cervical spinal stenosis and compression injury in aging using a newly-designed spinal compression device in young versus older rats and will ask if neuroprotective drugs can help protect the spinal cord fr
Cervical spinal injury and demyelination in aged rats
Most persons diagnosed with cancer do not report a single symptom; instead they have multiple symptoms associated with the disease and treatment. The interactive and cumulative effect of multiple symptoms adversely affects quality of life. Thre
Profile of Symptom Clusters Among Prostate Cancer Patients
Peers and peer networks are important proximal social influences across the lifespan starting at an early age, and, from a developmental perspective, few other microsystemic contexts are as important to children's healthy development. Indeed, t
Application of Descrete Homotopy Theory to the Study of Children's Social Networks and their Dynamics
Advertised for, interviewed and are hiring and begun training four locally-based lay part-time workers (promotora) (total 1.50 FTE) to deliver the educatioinal intervention. Completed piloting and refining curriculum. Begun data analysis of foc
Contra Caries: Preventing ECC Using a Promotora Model fo
The activities included in the parent grant, 1 R21 EB008804-01A2, which encompass those proposed in this supplemental request, are based on the implementation of the clinical research study from which data is gathered for the application of the
A FLUID-STRUCTURE INTERACTION METHOD FOR PATIENT-SPECIFIC CARDIOVASCULAR MODELING
This award is for technique development. The technique in this case represents a combination of neuronal manipulations of pairbonding prairie voles, and observations of resulting behavior in semi-natural enclosures. We propose that this combina
An animal model of parental care: Manipulating social environments with V1aR-RNAi
This Administrative Supplement is designed to both accelerate the pace and achievement, and broaden the scope, of scientific inquiry into sleep/insomnia in patients with implantable cardioverter defibrillators ??ICD?? through investigation of t
Sleep in cardiac patients with implantable cardioverter defibrillators (ICD)
Purchase of newly available commercial optical coherence tomography (OCT) swept source that operates at a center wavelength of 1um.
Multimode Adaptive Optics Retinal Imager for Diagnostics of Age-related Macular Deg
REPLACE EXHIBIT CASE; REMOVE DEFECTIVE EXHIBIT CASE AND REPLACE IAW WITH ATTACHED SPECIFICATIONS.
15KV High Voltage underground distribution cable 2500.00 ft with 1/0 Aluminum conductor with jacketed concentric nuetrals.  Cable is to be Okoguard URO-J full neutral Catalog#163-23-3072. Okoguard insulation: 220 mils; 133% insulation level del
Electrical Apparatus and Equipment, Wiring Supplies, and Related Equipment Merchant  Wholesalers
Telecom upgrade for Haskell University.  BIA
The purpose of the Delivery Order is to purchase Part No. CMW117, HIPS/SIPS Professional Software (inclusive of HIPS Multibeam Professional and SIPS Professional, Bathymetric data cleaning and validation EA Tool for multibeam, Single beam data,
National Telecommunication and Information Administration
The Broadband Technology Opportunities Program (BTOP) is a new competitive grant program that will enable consumers and businesses in unserved and underserved areas of the United States to access broadband services.  Booz Allen Hamilton support
Provide Hydrological Instrumentation:  pressure transducers, psig(s) with 50ft. of vented cable; psig(s) with 100ft. Of vented cable; SDI-12 Encoders
Provide Hydrological Instrumentation: SD112 to 4-20 MA converters; SDI-12+40 degrees inclinometers
Procurement and Installation of Acoustic Doppler Instrumentation
Purchase of 1 x 420E Caterpillar backhoe loader with requested delivery date of November 2009.
Provide 5 Compressed Natural Gas Heavy Duty Transit Buses to be used for public transportation in Springfield, VA.  Outcome: This contract will result in 5 high-quality, accurately built buses being delivered on time to the property.  Other Ite
To provide support for Grant System Training and User Support Services.
Recovery American Reinvestment and Recovery Act (ARRA) Inbound Recipient Reporting Support under the Central Data Exchange Network TDD_9.03
1. Replace existing HVAC units with high efficiency units. 2. Replace 15 ton and 6 ton HVAC units in dining areas. 3. Replace clerestory windows. 4. Re-roof building, solar panel renewable. 5. Replace Mercury Vapor lighting in Gym with T-5 fluo
Project Description:  The best way to learn a construction trade is through apprenticeship. Apprenticeship combines on-the-job training with formal classroom and hands-on instruction. Apprentices earn while they learn.  Partnering with the Alas
Cook Inlet Tribal Council Trades & Carpentry Pre-Employment Training Program
Childcare development - direct services and support of tribal college childcare center.
The Spirit Lake tribe & council for Tribal Employment Rights and the National Indian Ironworkers Training program to conduct these activities, to negotiate agreements: issue sub-contract: manage Financial accounts: process request for drawdown
Funding was awarded to provide additional Summer Youth positions to our current program.  Twenty-one additional positions will be created for both the summer of 2009 and 2010.  These positions will include 11 regular Summer Youth ages 14-21 and
The funding was alloted to provide training for Native American/Alaska Natives in the field of Energy Auditor Level II, which is designed to provide professional training and supportive services to individuals to conduct energy audits on reside
2009 Supplemental Youth Services Funds American Recovery and Reinvestment Act of 2009
The Blackfeet Manpower Supplemental Youth Employment Program is designed to assist youth ages 14 to 24 with employment and training. We work with our youth in helping prepare them for their future by offering work experience, program support, a
Renovate rest area, upgrade parking area, utilities and site work
Hot mix asphalt base crushing and shaping, hot mix asphalt surfacing, constructing shoulders, misc safety and drainage
Hot mix asphalt cold milling and surfacing and aggregate shoulders
Cold milling, hot mix asphalt resurfacing, curb and gutter, concrete sidewalk and ADA ramps
Hot mix asphalt cold milling and resurfacing
Hot mix asphalt cold milling and two course overlay and joint repairs
Hot mix asphalt resurfacing and aggregate
Hot mix asphalt resurface and reconstruction including pavement removal, aggregate base, hot mix asphalt
Hot mix asphalt road reconstruction including, storm sewer, concrete curb and gutter, watermain, concrete
Hot mix asphalt road resurfacing, including base crushing, guardrail upgrades and pavement markings
Hot mix asphalt road reconstruction, storm and sanitary sewer, landscaping and street lighting
Cold milling hot mix asphalt, hot mix asphalt
Hot mix asphalt overlay, cold milling, base repairs, aggregate shoulders and earthwork
Hot mix asphalt resurfacing, guardrail and pavement markings
Single chip seal of the existing hot mix asphalt mainline and paved shoulders, and placement of aggregate shoulder.
Hot mix asphalt paving, aggregate base conditioning, concrete curb and gutter, aggregate shoulders
Hot mixed asphalt road reconstruction, including curb and gutter replacement and drainage improvement
Cold milling hot mix asphalt and concrete
Cold milling concrete pavement, concrete pavement repairs, hot mix asphalt resurfacing, concrete curb and gutter
Concrete pavement repair and hot mix asphalt overlay
Concrete cracking and seating, cold milling concrete pavement, hot mix asphalt resurfacing, concrete pavement
Concrete cold milling, pavement repairs, hot mix asphalt overlay, intermittent curb and gutter replacement, sidewalk
Concrete pavement craking and seating, cold milling concrete pavement, concrete pavement repairs, hot mix asphalt
Pavement removal, drainage structures, cold milling, hot mix asphalt resurfacing and concrete sidewalk and ADA ramps
Hot mix asphalt cold milling and resurfacing, concrete curb and gutter, concrete sidwalk and ADA ramps
Hot mix asphalt overlay and pavement markings
Reconstruction, hot mix asphalt pavement, concrete curb and gutter, storm sewer, concrete sidewalk, and earthwork
Hot mix asphalt resurfacing, base crushing and shaping, aggregate shoulders and pavement markings
Cold milling hot mix asphalt and resurfacing, concrete pavement repair, guardrail replacement, sidewalk ramps
Hot mix asphalt surface remove, drainage improvements and hot mix asphalt paving.
Hot mix asphalt cold milling and overlay
Deck replacement, deck patch, joint replacement, steel repairs, pin and hangers, painting, substructure repairs
Reconstruction of I-275 Trail - Design Build
26 miles of HMA crack treatment, Muskegon TSC Wide
for implementing patient portals in disadvantaged communities.
Health Information Technology Innnovation Initiative
Design the following enhancements for Building 1 Extension (B1E): Liquid Helium Recovery System, Chemical/Gas storage, Humidity Control, Additional Boiler, Additional Chiller, Telecom Fit-up, Security B1E to Duct Bank to B1, Stairs at conferenc
A/E services for the Project Initiation and Discovery Part II for NIST Boulder B1E Cleanroom and B1E Fit-up design
This application addresses broad Challenge Area (01) Behavior, Behavioral Change, and Prevention and specific Challenge Topic, 01-AA-102*: Functional Roles of Neuroimmune Factors in Mediating Behavior. A critical unanswered challenge in underst
Changing Behavior by Shifting Th1/Th2 Balance in the Brain
This application from a collaboration between the Seufferheld and Blanke laboratories at the University of Illinois at Urbana-Champaign proposes studies to explore the overall hypothesis that Helicobacter pylori acidocalcisome-like granule (ALG
PPK Dependent Acidcalcisome-Like Granules Polyphosphates and Heliocobacter
Skeletal muscle differentiation is a well-orchestrated process regulated by autocrine, paracrine, and endocrine factors via a regulatory network of signal transduction pathways. In recent years the mammalian target of rapamycin (mTOR) has begun
This application addresses broad Challenge Area (03) Biomarker Discovery and Validation and specific Challenge Topic Identify and validate clinically relevant, quantifiable biomarkers of diagnostic and therapeutic responses for blood, vascular,
The Pediatric Sepsis Biomarker Risk Model
DNA sequencing technology has improved dramatically over recent years with orders of magnitude improvements in the yield of sequence data having resulted from applying massively parallel approaches. Helicos has taken next generation sequencing
PROVIDING THE $1000 GENOME VIA IMPROVED SINGLE MOLECULE SEQUENCING
The presence of engineered nanomaterials (NMs) in the environment is of human health concern. This project will produce reliable, sensitive and accurate methods for the determination of NMs in a broad spectrum of environmental and biological sa
Detection of engineered nanomaterials in drinking water, food, commercial products and biological samples
Nanopore sequencing offers the possibility of rapid single molecule sequencing with long reads, almost no sample preparation, and direct electronic readout from a small, computer-chip-like device. Nanopores are orifices that are so small that e
Carbon Nanotubes: A New Synthetic Nanopore for Sequencing
The overall goal of this project is to understand molecular mechanisms by which the nuclear bile acid receptor, farnesoid X receptor (FXR), regulates metabolic homeostasis in normal and diseased states. The specific goal of this application is
1R Improvements to Route 44 C-3A, from Tourtellotte Hill Rd. to State Maintenance Garage
These supplementary funds will enable us to resolve quickly two problems relating to Aim 1 of our current grant.  This Aim seeks to uncover the mechanisms by which hydrogen peroxide is formed inside aerobic cells, using E. coli as a model syst
The Physiology of Oxidative Stress in Escherichia Coli
Our goal during the past thirty years of NIH funding has been to understand the mechanism of chemotaxis in the Gram-positive bacterium Bacillus subtilis. During the past decade, the realization has emerged that the B. subtilis paradigm might be
Chemotactic Sensory Transduction in Bacillus Subtillis
Supplementary funding will result in professional employment for a Postdoctoral Research Associate in a position that fully utilizes his potential and affords him advanced training, while accelerating the pace of this project through to its com
Bioorganometallic Iron-Sulfide Assemblies Related to Hydrogenases
The long-term objective of this research project is to develop a detailed atomic-resolution structural and functional understanding of protein aggregation and fibrillation relevant to human disease, principally with studies of alpha-synuclein.
Structures of Protein Aggregates By Solid-State NMR
The primary focus of this proposal is the discovery and development of highly selective, catalytic allylic C-H functionalization reactions that can be broadly applied to synthesis. Using these reactions to develop strategies for effecting highl
Hydrocarbon Oxidation Methods for Synthesis
The research program addresses questions of fundamental importance to human health-biological design rules that determine whether cells respond to chemotactic signals by disrupting intercellular contacts in ways that fundamentally impact the or
Polarization and Directed Cell Movements in Engineered Cellular Environments
NIH ARRA administrative supplement to R21 HL088228.  An essential feature of inflammation is the emigration of leukocytes from the blood into damaged or infected tissue. Several evidences suggest that extracellular nucleotides play a critical r
Investigating the role of the P2Y2 nucleotide receptor in inflammation (NIH ARRA supplement R21 HL088228)
The Housing Authority of the City of Pawtucket is implementing the following activities using Capital Fund Recovery Act funding to implement a Solar Energy Utilization project for St Germain Manor. Solar photovoltaic panels will provide energy
Site Improvements including grounds improvements, fencing, walkway repairs, and parking upgrades.
The Housing Authority of the City of Pawtucket is implementing the following activities using Capital Fund Recovery Act funding for rehabilitation of its public housing developments as follows:Roof Replacement, Exterior Painting, Soffits/Fascia
Public Housing Capital Fund Stimulus funding for facilities modernization work and procurement of grounds maintenance equipment.
Installation of Windows and Vinyl Siding
Conduct modernization activities at Public Housing Development
This grant was awarded to RIPTA (the Rhode Island Public Transit Authority) to invest in public transportation by purchasing forty-foot (40') buses powered by hybrid-electric engines.  These vehicles will help RIPTA meet the service needs of it
ADMINISTRATIVE MANAGEMENT AND GENERAL MANAGEMENT CONSULTING SERVICES
Provide quality assurance support to DOE/RL. Individual tasks are assigned by the DOE/RL Assistant Manager for Safety and Environment, and deliverables are entered into the DOE/RL OA Database.
DESCRIPTION (provided by applicant): The current methods for cryopreservation of swine embryos are time consuming and troublesome. One of the most successful methods of cryopreservation of swine embryos is to centrifuge the cells to polarize th
High-throughput crypreservation of in vivo-derived swine embryos.
Window replacement at the Johnson County Administration Building
Installation of smaller 'baseline' hot water boiler and a variable frequency drive for water chiller in the energy plant for increased efficiency for cooling needs of County complex.
Minnehaha County Energy Conservation Retrofit Project
Overall purpose of the award project is to replace inefficient light fixtures and address underlit areas at Metra Park Arena, Pavilion & Expo Hall, in order to provide a safe environment while providing the most energy savings possible.  This g
Recovery Act - EECBG Program Metra Park Retrofit Lighting Project
EE Conservation Block Grant Program - Window Replacement
HAWAII HOUSING FINANCE AND DEVELOPMENT CORPORATION
The Homelessness Prevention and Rapid Re-housing Program (HPRP) grant is focused on housing for homeless and at-risk households.  The grant will provide temporary financial assistance and housing relocation and stabilization services to individ
Homeless Prevention and Rapid Rehousing Program
The Federally specified purpose of HPRP (Homelessness Prevention and Rapid Re-housing Program) funding is: to provide homelessness prevention assistance to households who would otherwise become homeless and to provide assistance to rapidly re-h
Homelessness Prevention and Rapid Re-Housing Program
TEMPORARY & DISABILITY ASSISTANCE, NEW YORK OFFICE OF
The purpose of the Homelessness Prevention and Rapid Re-housing Program (HPRP) is to provide assistance to households that have been identified as at-risk and who otherwise without such assistance would experience homelessness.  HPRP is also in
Homelessness Prevention and Rapid Rehousing Program
The North Carolina Homelessness Prevention and Rapid ReHousing Program will provide services to households in 57 of North Carolina's 100 counties.  The State program predicts preventing homelessness for 1600 households and rapidly re-housing 62
Homelessnes Prevention and Rapid ReHousing Program
Homeless prevention and re-housing project provides financial assistance and services to prevent individuals and families from becoming homeless and help those who are experiencing homelessness to be quickly re-housed and stabilized.
Homeless Prevention & Rapid Re-Housing Program
The Homelessness Prevention and Rapid Re-Housing Program (HPRP) award is Recovery Act funding provided to communities to provide financial assistance and services to either prevent individuals and families from becoming homeless or help those w
HOUSING AND COMMUNITY DEVELOPMENT, VIRGINIA DEPT OF
The State plans to use HPRP funds for both homelessness prevention and rapid re-housing.  The State has allocated to 23 subgrantees across the state.  The jurisdictions include metropolitan cities and urban counties that receive their own alloc
State Homelessness Prevention and Rapid Re-housing Program
The purpose of the HPRP is to provide homelessness prevention assistance to households who would otherwise become homeless - many due to the economic crisis - and to provide assistance to rapidly re-house persons who are experiencing homelessne
Funds will be used to provide homelessness prevention assistance to households who would otherwise become homeless and to provide assistance to rapidly re-house persons who are homeless.  The funds are intended to target two populations: 1) ind
Homelessness Prevention and Rapid Re-Housing
Homeless Prevention and Rapid Re-Housing Program (HPRP)
The City of Tempe is utilizing HPRP funds to rapidly re-house a minimum of 35 homeless individuals.  Tumbleweed, our sub-recipient, is rapidly re-housing young adults who are homeless.
Provide assistance to Salinas households at 50% or below of AMI who are currently in housing but at risk of becoming homeless; those who are experiencing homelessness and need temporary assistance in order to retain and obtain housing; and indi
HPRP-HP-Housing Resource Center of Mo. Co.
San Francisco' HPRP program focuses on preventing homelessness and facilitating the quick re-housing of homeless people while partnering with mainstream services and other ARRA-funded programs. Services will be provided by six community-based,
HPRP - Homelessness Prevention & Rapid Re-Housing Program
The funds will be used to provide rent assistance and other services to prevent households from becoming homeless or to re-house households that have already become homeless.
The Homelessness Prevention and Rapid Re-Housing Program will provide financial assistance and services to prevent individuals and families from becoming homeless and help those who are experiencing homelessness to be quickly re-housed and stab
THE HOMELESS PREVENTION AND RAPID RE-HOUSING PROGRAM (HPRP)SERVES THE HOMELESS AND THOSE AT RISK FOR HOMELESSNESS WITH FINANCIAL ASSISTANCE AND HOUSING RELOCATION SERVICES IN THE CITY OF EL CAJON.  RENT AND UTILITY ASSISTANCE IS AVAILABLE FOR T
The goal of the City of San Diego Homelessness Prevention and Rapid Re-Housing Program is to prevent people from becoming homeless, divert those entering the shelter system to permanent housing options, and rapidly re-house those who are alread
City of San Diego Homelessness Prevention and Rapid Re-Housing Program
The City of Oceanside will use funds provided through the Homelessness Prevention and Rapid Re-Housing Program (HPRP) primarily for households with children ages 0-18 to help the family maintain a secure and stable home environment.  The City w
The Homeless Prevention and Rapid Re-Housing Program (HPRP) is part of the American Recovery and Reinvestment Act of 2009 and is designed to either prevent individuls and familes from becoming homeless or help those whoare experiencing homeless
HPRP provides homelessness prevention for those at risk and rapid re-housing for those already homeless. The City of Atlanta funded 21 HPRP projects, of which 19 were services, 1 was data collection and analysis, and 1 was administrative. For t
Homelesness Prevention and Rapid Re-Housing Program
Homelessness Prevention and Rapid Re-Housing Program:  Funds to be used to provide financial assistance and services to prevent individuals and families from becoming homeless or help those who are experiencing homelessness to be quickly re-hou
ATHENS-CLARKE COUNTY, UNIFIED GOVERNMENT OF
Athens-Clarke County has allocated $604,969 to four sub recipients for a period of three years to fund homelessness prevention and rapid re-housing activities for households (individuals & families) who are homeless or at risk of becoming homel
Homeless Prevention and Rapid Re-Housing Program
Community Improvement & Capacity Building N.E.C.
The purpose of the Homelessness Prevention and Rapid Re-Housing Program is to provide homelessness prevention assistance to households who would othewise become homeless, many due to the economic crisis, and to provide assistance to rapidly re-
The award money provided aid to families and households to those in need of assistance and to those who were Homeless and to those at risk of becoming Homeless.
Homeless Prevention and Rapid Re-Housing
Homelessness Prevention and Rapid Re-Housing Program assists eligible people experiencing homelessness as well as those at risk of homelessness with obtaining housing.
Homlessness Prevention and Rapid Re-Housing Program (HPRP) funding provides assessment, triage, case management services, as well as eligible financial assistance to homeless families and individuals in Worcester, MA.
Homelessness Prevention and Rapid Re-Housing Program (HPRP)
Homeless Prevention and Rapid Re-Housing Program: The purpose is to provide financial assistance and services to either prevent individuals and families from becoming homeless or help those who are experiencing homelessness to quickly rehouse a
Homelessness Prevention and Rapid Re-Housing Program:  to provide financial assistance and services to either prevent individuals and families from becoming homeless or help those who are experiencing homelessness to quickly re-house and stabil
City of Omaha Homelessness Prevention Program
The city of Las Vegas will spend $230,000 on preventing those families of homelessness by providing financial assistance in the form of short and medium-term rental assistance, deposits, utility payments and short-term rental vouchers. Current
City of Las Vegas Homeless Prevention and Rapid Re-Housing Program
The City will utilize funds from the ARRA in the amount of $361,841 for the milling and paving of a portion of Artic Ave and installation of conduit for traffic signalization and timing.  An effort was made to identify a project that could b
The Homeless Prevention and Rapid Re-Housing Program (HPRP)was established for residents who but for this assistance would become homeless. Our subrecipients, non-profit social service agencies, assisted income eligible clients with credit coun
The City of Jersey City is one of three municipalities within Hudson County designated to receive a direct Homeless Prevention and Rapid Re-housing Program award from the United States Department of Housing and Urban Development. HPRP grants wi
The overall purpose of the electronic health record (EHR) project (Alabama Healthcare Consortium Network EHR Implementation) is to support the Health Center Controlled Network (HCCN) known as the Alabama Healthcare Consortium Network (AHCN) to
Alabama Healthcare Consortium Network - OHIT Implementation/Planning Grant
To assist in operating statewide comprehensive, coordinated, effective, efficient and accountable programs of vocational rehabilitation, which are an integral part of a statewide workforce investment system; and designed to assess, plan, develo
This ARRA funding will assist in operating statewide comprehensive, coordinated, effective, efficient and accountable programs of Vocational Rehabilitation which are an integral part of a statewide workforce investment system and designed to as
Vocational Rehabilitation Services - ARRA
ARRA Basic Support - Improve employment outcomes for individuals with disabilities, especially those with the most significant disabilites.  Assist in operating statewide comprehensive, coordinated, effective, effcient and accountable program o
Vocational Rehabilitation Grants to States, Recovery Act/Basic Support
VOCATIONAL REHABILITATION DEPARTMENT, SOUTH CAROLINA
Assist in operating statewide comprehensive, coordinated, effective, efficient and accountable programs of vocational rehabilitation, which are an integral part of a statewide workforce investment system and designed to assess, plan, develop, a
HUMAN SERVICES, SOUTH DAKOTA DEPARTMENT OF
Grants to  States for the Education of Children with Disabilities
MISSISSIPPI STATE DEPARTMENT OF EDUCATION
Special Education - Grants to States, Recovery Act
'Assist States to make available special education and related services for children with disabilities age 3 through 5 years, and at a State's discretion, to 2 year old children with disabilities who will reach age three during the school year.
Alaska Department of Education & Early Development
806 West 10th St, Suite 200 P.O Box 110500
Assist States to make available special education and related services for children with disabilities age 3 through 5 years and at a State's discretion to 2 year old children with disabilities who will reach age three during the school year.
Assist States to make available special education and related services for children with disabilities ages 3 through 5 years, and at a State's discretion, to 2 year old children with disabilities who will reach age three during the school year.
Assist States to make available special education and related services for children with disabilities age 3 through 5 years and at a State's discretion, to 2 year old children with disabilities who will reach age three during the school year.
Special Education - Preschool Grants, Recovery Act to assist State make available special education and related services for children with disabilities age 3 through 5 years.
Special Education - Preschool Grants, Recovery Act
Assist States in the implemmentation of a statewide, comprehensive, coordinated, multidisciplinary, interagency system of early intervention services for infants and toddlers with disabilities and their families.
Early Intervention System for Infants and Toddlers with Disabilities
The Alaska Department of Health and Social Services, Office of Children's Services, Infant Learning Program plans to develop infrastructure and implement a personnel development plan to adhere to IDEA 2004-highly qualified teachers.  The Depart
Assist districts in the implementation of a statewide, comprehensive, coordinated, multidisciplinary, interagency system of early intervention services for infants and toddlers with disabilities and their families. Please note that $7,455,913.7
Early Intervention Program for Infants and Toddlers
Part C of the Individuals with Disabilities Education Act (IDEA) - Special Education - Grants for Infants and Families 'Recovery Funds'. Funding from the ARRA will be allocated to county Family and Children First Councils for program services a
Special Education - Grants for Infants and Families, Recovery Act
Kentucky's First Steps program is authorized by Part C of the Individual with Disabilities Education Improvement Act (IDEA).  First Steps provides developmental services to infants and toddlers from birth to age three who are experiencing devel
Kentucky Part C Early Intervention System (KEIS) - First Steps
Assist State in the implementation of a statewide, comprehensive, coordinated, multidisciplinary, interagency system of early intervention for infants and toddlers with disabilities and their families.
Independent Living Services for Older Individuals Who Are Blind, Recovery Act
IDAHO COMMISSION FOR THE BLIND & VISUALLY IMPAIRED
Independent Living Older/Blind, Recovery Act
ASSISTIVE & REHABILITATIVE SERVICES, TEXAS DEPARTMENT OF
Parsons Downtown Improvements - Phase II
H47C2305365001 - Highway Infrastructure Investment
H47C2400066039 - Highway Infrastructure Investment
H47C2400403137 - Highway Infrastructure Investment
COMMUNITY HEALTH CENTER OF THE BLACK HILLS, INC.
Recovery Act Health Center Cluster Program - General Beadle School Based Clinic
The Ingham County Health Department (ICHD) has worked with hard-to-serve populations since the 1970s when it established primary care services as part of a Model Cities initiative. The Department’s model of care has evolved over time respondi
A Community Health Center New Access Point HRSA Grant Award that enables the provision of primary and preventive health care services to the Central Lansing, Michigan Medically Underserved Service Area.
This New Access Point (NAP) grant has allowed North Country HealthCare to open and sustain a new primary care clinic in Show Low, Arizona.  The goals of this effort were to open a new facility in Show Low, and staff the clinic with qualified me
Recovery Act Health Center Cluster. This is a New Access Point grant for Laurens County in Georgia. Community Health Care Systems, Inc., an accredited organization with twenty years of expertise in providing health care to the uninsured and und
Recovery Act Health Center Cluster Program provided funding through grant funding to create New Access Points (NAP)to provide health care services in communities not being served by a health center. The goals of the program was to open and cont
This ARRA funding from HRSA was for a New Access Point for a Federally Qualified Health Center in Adair County, Oklahoma. This expansion created a healthcare clinic where prior, there was not one. Adair County is the second poorest county in Ok
Award of Homelessness Prevention and Rapid Rehousing Program monies
City of Utica, New York Homelessness Prevention and Rapid Rehousing Program
Homelessness Prevention and Rapid Re-Housing Program - Funds will provide for temporary financial assistance to prevent homelessness and stabilize housing situations and various supportive services including: counseling, outreach, legal and cas
Yonkers Homelessness Prevention and Rapid Rehousing Program The City of Yonkers? Homelessness Prevention and Rapid Rehousing Program (HPRP) received $1,533,003 in federal HPRP funding and is designed to achieve two purposes:  1. prevent evictio
$509,460 will support the City of Asheville's Homeless Prevention and Rapid Re-Housing Program (HPRP). This program is designed to prevent homelessness or rapidly re-house households (individuals and families) who would be homeless -but for- th
The City of Asheville Homelessness Prevention and Rapid Re-housing Program
This Homelessness Prevention and Rapid Re-Housing (HPRP) grant provides financial assistance and services to either prevent individuals and families from becoming homeless or help those who are experiencing homelessness to be quickly re-housed
The Homelessness Prevention and Rapid Rehousing Program (HPRP) is designed to provide one-time or temporary housing assistance to household who would be homeless but for the assistance and who would have a likelihood of being stable in housing
Dept. of Planning & Community Development
The City has signed four sub-recipient agreements to help combat the homeless issue within the City of Johnstown.
Funding for homelessness prevention and rapid re-housing for people in the City of Bethlehem
Homeless Prevention and Rapid Re-housing Program
Pawtucket's HPRP funding has been awarded to five local non-profits to both assist households from becoming homeless and assist those households who are homeless find apartments. It is anticipated that 258 households will be assisted over the t
Homeless Prevention and Rapid Re-housing
No sub awards will be under $25,000.  These grants funds will provide assistance for the homeless and the prevention of homelessness for the City of Columbia, SC. Activities will include Case management, housing counseling, financial assitance,
Rehousing assistance for the homeless and prevention of homelessness by stabilizing those at risk through rental and utility assistance supported by case management.
The City of Plano used HPRP funds for Homelessness Prevention Services. Specifically, funds provided rent and utility assistance for a maximum of nine months and legal services to Plano residents making 50% or below of the Median Area Income.
City of Plano HPRP Homelessness Prevention and Rapid Re-Housing Program
Homelessness Prevention and Rapid Re-Housing Program. Provides financial assistance and services to either prevent individuals and families from becoming homeless or help those who are experiencing homelessness to be quickly rehoused and stabil
HPRP-Homelessness Prevention and Rapid Re-Housing Program
Homelessness Prevention and Rapid Re-Housing Program (HPRP) to be used by subrecipient agencies to provide financial assistance, housing relocation and housing stabilization services to homeless or potentially homeless clientele.
Newport News Homelessness Prevention and Rapid Re-Housing Program
The City of Richmond’s Homeless Prevention and Rapid Re-Housing (HPRP) program will provide homeless prevention, diversion and rapid re-housing services to eligible clients residing in the City of Richmond through the funding of eight project
Homeless Prevention and Rapid Re-housing Program. The purpose is to provide financial assistance and services to either prevent individuals and families from becoming homeless or to help those who are experiencing homeless to be quickly re-hous
To provide financial and other assistance to prevent individuals and families from becoming homeless and help those who are experiencing homelessness to be quickly re-housed and stabilized.
CALLE PALMER ESQUINA AGUSTÍN LOPEZ # 105
Provide Financial assistance to prevent individual and families becoming homeless and to assist those that already homeles to be quickly rehouse and stabilized.
Homelessness Prevention and Re-housing Program
Homelessness Prevention and Rapid Re-Housing Program: the purpose of this program is to provide financial assistance and services to either prevent individuals and families from becoming homeless or help those who are experiencing homelessness
Volusia County through its Community Assistance Division will implement the HPRP and directly provides services to the program participants. HPRP staff will provide program training and technical assistance to the Continuum of Care (CoC) partne
Homelessness Prevention and Rapid Re-Housing Program (HPRP).  The funds are used to provide financial assistance and services to either prevent individuals and families from becoming homeless or help those who are experiencing homelessness to b
Clayton County Housing and Community Development Program Office implementation of the United States Department of Housing and Urban Development Homeless Prevention and Rapid Re-Housing Program (HPRP) began October 1, 2009. 	The purpose of the H
This grant is used to provide housing stability to persons at-risk of homelessness or those literally homeless. Assistance may be provided up to 18 months and can assist with rent, security deposit, utility costs and other eligible activities.
Homelessness Prevention Rapid Re-Housing Program
The funds will be utilized to expand the existing homeless and near homeless programs for needy families in St. Clair County.  The county intends to assist clients with Short & Medium Rental Assisistance, security deposits, utility payments, ca
St. Clair County Homlessness Prevention/Rapid Rehousing Program
The Homelessness Prevention and Rapid Re-Housing Program will enable the Montgomery County Department of Health and Human Services (MCDHHS)to provide financial assistance and casemanagement services to low-income residents to prevent homelessne
FY 2009 (FFY 2008) Substantial Amendment to the Consolidated Action Plan for the Homelessness Prevention and Rapid Re-Housing Program (HPRP)
Provide financial assistance and case management for housing stabilization for households who are below 50 percent area median income and are homeless or who are at imminent risk of homelessness.
Homeless Prenvention and Rapid Rehousing Program
The Homeless Prevention and Rapid Re-Housing program assisted households at-risk of homelessness, or who were already homeless.
Homelessness Prevention and Rapid Re-housing Program.  Funds are intended to target two populations of person facing housing instability: 1)families and individuals who are currently in housing but are at risk of becoming homeless & need tempor
This award was made to provide homeless prevention and rapid re-housing program (HPRP) services to individuals and families in Cumberland County. These funds are being used to provide financial assistance in the form of rental payments, securit
Community Development: Project 1 - Catholic Charities will be initiating a Homelessness Prevention program for $106,600.00 to promote family stability among residents of Lehigh County whose annual incomes are at or below 50% of the area median
Lehigh County Homelessness Prevention and Rapid Re-housing program
Pursuant to the American Recovery and Reinvestment Act, Charleston County was Homeless Prevention and Rapid Re-Housing funding to provide funding to Charleston County residents who are currently homeless or at risk of becoming homeless.  This f
Homelessness Prevention and rapid Re-Housing Program; Purpose is to provide financial assistance and services to either prevent individuals and families from becoming homeless or help those who are experiencing homelessness to quickly be re-hou
HPRP funds are being used to fund two(2) programs.  Fort Bend County Social Services Department, 4520 Reading Road, Rosenberg, TX, provides housing and utility assistance to individuals and families to prevent homelessness or to re-house from a
Fort Bend County Community Development Dept.
Funds were awarded to 5 agencies that serve various areas in the County.  These agencies assisted people who had a hardship and could not pay their rent and/or utilities.  We projecting to help over 300 families by paying their rent and/or util
The award title for this grant is the Homelessness Prevention and Rapid Re-Housing Program. The purpose of the grant is for Bexar County to provide financial assistance and services to either prevent individuals and families from becoming homel
Homelessness Prevention and Rapid Re-Housing Program (Recovery Act Funded)
HPRP resources are targeted and prioritized to serve households that are most in need of this temporary assistance and are most likely to achieve stable housing, whether subsidized or unsubsidized.  Funds are intended to target 2 populations: a
Homelessness Prevention and Rapid Re-Housing (HPRP)
Funds to purchase a Leica SP5 laser scanning confocal microscope for communal use.
Leica TCS SP5 laser scanning confocal microscope
The primary goal of the ARRA EETT grant is to improve student academic achievement through the use of technology in elementary and secondary schools. The State goal is to (1) assist every student in crossing the digital divide by ensuring that
Title II, Part D, Enhancing Education Through Technology
Educational Technology State Grant to States to improve student academic achievement through the innovative use and the effective integration of new and emerging technology with teacher training curriculum development and successful research-ba
Title II Part D--Enhancing Education Through Technology
Educational Technology State Grants to States to improve student academic achievement through the innovative use and the effective integration of new and emerging technology with teacher training, curriculum development, and successful research
Title II, Part D -- Enhancing Education Through Technology.
The goals of the Educational Technology State Grants to States are: 1) to improve sutdent academic achievement through the innovative use and 2) the effective integration of new and emerging technology with teacher training, curriculum developm
Title II, Part D - Enhancing Education Through Technology.
Education of Homeless Children and Youth, Recovery Act funds are to ensure that all homeless children and youth have equal access to the same free, appropriate public education available to other children.
Education of Homeless Children and Youth, Recovery Act
Funding to further expand and implement services to homeless children and youth.
Ensure that each homeless child and youth has equal access to the same free, appropriate public education, including a public preschool education, as other children and youth.
Education for Homeless Children and Youth
Funds are used for staff serving infants/ toddlers with disabilities, for training of staff for infants/toddlers with disabilities, for diagnostic services and materials, for related services, for assistive technology which includes computers a
EDUCATION FOR HOMELESS CHILDREN AND YOUTH
Ensure that each homeless child and youth has equal access to the same free, appropriate public education including a public preschool education, as other children and youth
Ensure that each homeless child and youth has equal access to the same free, apprepriate public education, including a public preschool education, as other children and youth.
PUBLIC INSTRUCTION, WASHINGTON STATE SUPERINTENDENT OF
Ensure that each homeless child and youth has equal access to the same free, appropriate, public education, including a public preschool education, as other children and youth.
Ensure that each homeless child and youth has equal access to the same free, quality, appropriate public education, including a public preschool education, as other children and youth.
Title I - Grants to LEAs, Recovery Act funds to improve teaching and learning for students most at risk of failing to meet State academic achievement standards.
Title I, Part A--Improving Basic Programs Operated by Local Educational Agencies
Improve teaching and learning for students most at risk of failing to meet State academic achievement standards.
Title I, Part A -- Improving Basic Programs Operated by Local Educational Agencies
Title I, Part A - Improving Basic Programs Operated by Local Educational Agencies
Title I, Part A--Improving Basic Programs Operated by Local Educational Agencies.
Improve teaching and learning for students most at risk of failing to meet State Academic Achievement Standards.
Title I Grants to Local Educational Agencies, Recovery Act
This award supports improved teaching and learning for students most at risk of failing to meet state academic achievement standards within school districts with high percentages of students from families in poverty.
Title I, Part A: Grants to Local Educational Agencies
ELEMENTARY AND SECONDARY EDUCATION, MASSACHUSETTS DEPARTMENT OF
Education Fund - for the support of public elementary , secondary, postsecondary and, as applicable, early childhood education programs and services.
State Fiscal Stabalization Fund-Education Grants, Recovery Funds
EXECUTIVE OFFICE OF THE STATE OF MICHIGAN
Education Stabilization funds support public elementary, secondary, and postsecondary education programs and services.
State Fiscal Stabilization Fund-Education Fund
EXECUTIVE OFFICE OF THE STATE OF MINNESOTA
Education Fund - for the support of public elementary, secondary, and postsecondary education and, as, applicable, early childhood education programs and services.
State Fiscal Stabilization Fund - Education Fund
For the support of public elementary, secondary, and post secondary education and, as, applicable early childhood education programs and services