GIVE NOW about ocw help & faqs contact us
9.322J | Fall 2005 | Graduate

# Genetic Neurobiology

### Course Meeting Times

Lectures: 2 sessions / week, 1.5 hours / session

### Course Summary

This course presents the information that has been collected from studying genetic variation in model systems like nematode and drosophila for mutation studies. Also, new tools that are available to manipulate gene expression, and genes of interest in specific regions of the brain, will be presented. Some of these manipulations are at the ionic channel level, while others are at the organism level. By changing gene expression patterns during development through knockouts, conditional knockouts, or overexpression, the changes in the system can be explored. Diseases that are the result of loss of expression or missing genes in humans will also be studied.

### Course Format

The first session of the week will consist of a lecture given by one of the instructors of the course. During the second session of the week, two students will give paper presentations and lead a class discussion (typically 15 to 25 minutes each) on a selected assigned paper for that week.

### Assignments

Paper summaries on the readings are required each week. Each student is required to make two oral presentations and lead a class discussion on a selected assigned journal paper for a particular week. There is also a final exam for this course.

## Course Info

##### Instructors

- Prof. Troy Littleton
- Prof. William Quinn

##### Departments

- Brain and Cognitive Sciences
- Biology

##### As Taught In

Fall 2005

##### Level

Graduate

##### Topics

- Science
  - Biology
    - Genetics
    - Neurobiology

##### Learning Resource Types

assignment Written Assignments
assignment Presentation Assignments

# You are leaving MIT OpenCourseWare

Please be advised that external sites may have terms and conditions, including license rights, that differ from ours. MIT OCW is not responsible for any content on third party sites, nor does a link suggest an endorsement of those sites and/or their content.