Recent Submissions

  • Structural and biochemical characterization of RNA polymerase II transcription 

    Su, Bonnie G. (Massachusetts Institute of Technology, 2025-02)
    Eukaryotic development requires precise temporal regulation of gene expression orchestrated through a series of complex mechanisms. One such mechanism involves pausing of RNA polymerase II (Pol II) in the promoter-proximal ...
  • Synaptic Multimodal Imaging and Molecular Network Inference 

    Falkovich, Reuven (Massachusetts Institute of Technology, 2024-05)
    All cognitive function is reliant on synaptic function – the molecular computation that integrates activity history, chemical environment, and the genetic state of its pre- and post-synaptic neurons to modulate neuron-neuron ...
  • Sideroflexins enable mitochondrial transport of polar neutral amino acids 

    Block, Samuel (Massachusetts Institute of Technology, 2025-02)
    Mitochondria contribute to compartmentalized metabolism in eukaryotic cells, facilitating diverse enzymatic reactions that support cell function. However, this compartmentalization of metabolism necessitates regulated ...

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