Doctoral Theses: Recent submissions
Now showing items 178-180 of 23243
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Machine Learning Methods for Single Cell RNA-Sequencing Data to Improve Clinical Oncology
(Massachusetts Institute of Technology, 2025-05)Single-cell RNA sequencing (scRNA-seq) offers a detailed view of the cellular and phenotypic composition of healthy and diseased tissues. While machine learning (ML) methods are well-suited for the high-dimensional nature ... -
Engineering TEV Protease Specificity: An Exploration of Machine Learning and High-Throughput Experimentation for Protein Design
(Massachusetts Institute of Technology, 2025-05)Engineering sequence-specific proteases would enable a wide variety of therapeutic applications in diseases ranging from cancer to Parkinson’s disease. However, many previous experimental and physics-based attempts at ... -
Learning-Guided Optimization for Intelligent Mobility Systems
(Massachusetts Institute of Technology, 2025-05)Efficient and reliable mobility systems are essential to modern-day society, with broad impacts ranging from day-to-day commuting, public transportation, emergency response to last-mile package delivery and freight logistics. ...
