Doctoral Theses: Recent submissions
Now showing items 268-270 of 23320
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Fundamental representations of regions and interactions in spatial transcriptomics
(Massachusetts Institute of Technology, 2025-05)While cells are often considered the fundamental unit of biology, it is their spatial coordination that gives rise to the tissue architectures underlying both health and disease. Spatial transcriptomics technologies offer ... -
Deciphering Features of Protective or Maladaptive Cellular Immunity in the Airways Following Primary and Repeated Pathogen Exposure
(Massachusetts Institute of Technology, 2025-05)The human respiratory tract is constantly subject to environmental stressors and perturbations that cause deviations from homeostatic conditions. The airway’s cellular constituents – epithelial, stromal, and immune cells ... -
Expansion Microscopy of Extracellular Space for Light Microscopy-Based Connectomic Analysis
(Massachusetts Institute of Technology, 2025-05)In this dissertation, we present an exploratory methodology, termed expansion microscopy of extracellular space (ExECS), designed to enhance the visualization of the extracellular space (ECS) within aldehyde-fixed tissue. ...
