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Insulin Delivery Pumps for Human Spaceflight: Steps Toward an Accessible Space Future

Author(s)
Horn, Kyle J; Hoffman, Jeffrey A
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Creative Commons Attribution-Noncommercial https://creativecommons.org/licenses/by-nc/4.0/
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Abstract
Commercially available insulin pumps for treatment of diabetes mellitus are currently not qualified to operate in the space environment. This work rigorously tested the fluid delivery performance of a Tandem t:slim X2 insulin pump in both micro- and hypergravity during a parabolic microgravity research flight. The parabolic research flight environment serves as an analogue to the types of transient gravitational loadings experienced during human-led missions, which provides a foundation to expand testing to suborbital and orbital flights in addition to other extreme environmental tests for wilderness dependency. The results of the flight data showed no significant difference between fluid delivery performance at 0, 1, and 2g acceleration regimes, nor at the transitions between gravity environments. Recommendations are made for further experimentation and qualification tests before use in future spaceflight missions.
Date issued
2025-09
URI
https://hdl.handle.net/1721.1/165089
Department
Massachusetts Institute of Technology. Department of Aeronautics and Astronautics
Journal
Wilderness & Environmental Medicine
Publisher
SAGE Publications
Citation
Horn KJ, Hoffman JA. Insulin Delivery Pumps for Human Spaceflight: Steps Toward an Accessible Space Future. Wilderness & Environmental Medicine. 2025;36(1_suppl):81S-88S.
Version: Final published version

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