MIT Open Access Articles: Recent submissions

Now showing items 124-126 of 55794

    • TCR signal strength defines distinct mechanisms of T cell dysfunction and cancer evasion 

      Shakiba, Mojdeh; Zumbo, Paul; Espinosa-Carrasco, Gabriel; Menocal, Laura; Dündar, Friederike; e.a. (Rockefeller University Press, 2022-02-07)
      T cell receptor (TCR) signal strength is a key determinant of T cell responses. We developed a cancer mouse model in which tumor-specific CD8 T cells (TST cells) encounter tumor antigens with varying TCR signal strength. ...

    • Allocation of resources among multiple daughter cells 

      Wirshing, Alison CE; Alonso-Matilla, Roberto; Yan, Michelle; Khalid, Samra; Colarusso, Analeigha V; e.a. (Rockefeller University Press, 2025-11-03)
      Cell division commonly produces two daughter cells, but there are many exceptions where large cells produce multiple daughters. Multiple fission of some green algae and bacteria; cellularization during embryogenesis of ...

    • Mechanisms of nuclear segregation in a multinucleate multibudding yeast 

      Petrucco, Claudia A; Crocker, Alex W; Wirshing, Alison CE; Colarusso, Analeigha V; Waarts, Maya; e.a. (Rockefeller University Press, 2025-11-03)
      Budding yeasts present an especially challenging geometry for segregation of chromosomes, which must be delivered across the narrow mother–bud neck into the bud. Studies in the model yeast Saccharomyces cerevisiae have ...