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Gene Expression Changes in the Motor Cortex Mediating Motor Skill Learning
(Public Library of Science, 2013-04)
The primary motor cortex (M1) supports motor skill learning, yet little is known about the genes that contribute to motor cortical plasticity. Such knowledge could identify candidate molecules whose targeting might enable ...
Task Dependence of Visual and Category Representations in Prefrontal and Inferior Temporal Cortices
(Society for Neuroscience, 2014-11)
Visual categorization is an essential perceptual and cognitive process for assigning behavioral significance to incoming stimuli. Categorization depends on sensory processing of stimulus features as well as flexible cognitive ...
What about the “Self” is Processed in the Posterior Cingulate Cortex?
(Frontiers Research Foundation, 2013-10)
In the past decade, neuroimaging research has begun to identify key brain regions involved in self-referential processing, most consistently midline structures such as the posterior cingulate cortex (PCC). The majority of ...
The Computational Structure of Spike Trains
(MIT Press, 2010-01)
Neurons perform computations, and convey the results of those computations
through the statistical structure of their output spike trains. Here we
present a practical method, grounded in the information-theoretic ...
Applying the multivariate time-rescaling theorem to neural population models
(MIT Press, 2011-05)
Statistical models of neural activity are integral to modern neuroscience. Recently interest has grown in modeling the spiking activity of populations of simultaneously recorded neurons to study the effects of correlations ...
Production of glycoprotein-deleted rabies viruses for monosynaptic tracing and high-level gene expression in neurons
(Nature Publishing Group, 2010-03)
Recombinant rabies viruses rendered replication-deficient by the deletion of their envelope glycoprotein gene are useful tools for neuroscientists, permitting (1) extraordinarily high transgene expression levels within ...
The Briefest of Glances: The Time Course of Natural Scene Understanding
(Psychological Science, 2009-04)
What information is available from a brief glance at a novel scene? Although previous efforts to answer this question have focused on scene categorization or object detection, real-world scenes contain a wealth of information ...
Learning substrates in the primate prefrontal cortex and striatum: sustained activity related to successful actions
(Elsevier Inc., 2009-07)
Learning from experience requires knowing whether a past action resulted in a desired outcome. The prefrontal cortex and basal ganglia are thought to play key roles in such learning of arbitrary stimulus-response associations. ...
An Overview of Bayesian Methods for Neural Spike Train Analysis
(Hindawi Publishing Corporation, 2013)
Neural spike train analysis is an important task in computational neuroscience which aims to understand neural mechanisms and gain insights into neural circuits. With the advancement of multielectrode recording and imaging ...
A Septin-Dependent Diffusion Barrier at Dendritic Spine Necks
(Public Library of Science, 2014-12)
Excitatory glutamatergic synapses at dendritic spines exchange and modulate their receptor content via lateral membrane diffusion. Several studies have shown that the thin spine neck impedes the access of membrane and ...