MIT Open Access Articles: Recent submissions
Now showing items 1-3 of 55257
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Machine learning prediction of antibody aggregation and viscosity for high concentration formulation development of protein therapeutics
(Informa UK Limited, 2022-01-25)Machine learning has been recently used to predict therapeutic antibody aggregation rates and viscosity at high concentrations (150 mg/ml). These works focused on commercially available antibodies, which may have been ... -
Enhanced O-glycosylation site prediction using explainable machine learning technique with spatial local environment
(Oxford University Press, 2025-02-04)Motivation: The accurate prediction of O-GlcNAcylation sites is crucial for understanding disease mechanisms and developing effective treatments. Previous machine learning (ML) models primarily relied on primary or secondary ... -
Leveraging microtopography to pattern multi-oriented muscle actuators
(Royal Society of Chemistry, 2025-03-14)Engineering skeletal muscle tissue with precisely defined alignment is of significant importance for applications ranging from drug screening to biohybrid robotics. Aligning 2D contractile muscle monolayers, which are ...
