MIT Open Access Articles: Recent submissions
Now showing items 1-3 of 53825
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Accelerating Diverse Cell-Based Therapies Through Scalable Design
(Annual Reviews, 2024-07-24)Augmenting cells with novel, genetically encoded functions will support therapies that expand beyond natural capacity for immune surveillance and tissue regeneration. However, engineering cells at scale with transgenic ... -
Guaranteeing System-level Properties in Genetic Circuits Subject to Context Effects
(IEEE, 2024-12-16)The identification of constraints on system parameters that will ensure that a system achieves desired requirements remains a challenge in synthetic biology, where components unintentionally affect one another by perturbing ... -
Engineered transcription factor-binding arrays for DNA-based gene expression control in mammalian cells
(Elsevier BV, 2025-06)Tools that manipulate gene expression in mammalian cells without any additional expression are critical for cell engineering applications. Here, we demonstrate the use of arrays of transcription factor (TF) recognition ...
