MIT Open Access Articles: Recent submissions

Now showing items 160-162 of 55688

    • Functional genetics reveals modulators of antimicrotubule drug sensitivity 

      Su, Kuan-Chung; Radul, Elena; Maier, Nolan K; Tsang, Mary-Jane; Goul, Claire; e.a. (Rockefeller University Press, 2025-02-03)
      Microtubules play essential roles in diverse cellular processes and are important pharmacological targets for treating human disease. Here, we sought to identify cellular factors that modulate the sensitivity of cells to ...

    • Chemical transformation of the multibudding yeast, Aureobasidium pullulans 

      Wirshing, Alison CE; Petrucco, Claudia A; Lew, Daniel J (Rockefeller University Press, 2024-06-27)
      Aureobasidium pullulans is a ubiquitous polymorphic black yeast with industrial and agricultural applications. It has recently gained attention amongst cell biologists for its unconventional mode of proliferation in which ...

    • Tunable DNMT1 degradation reveals DNMT1/DNMT3B synergy in DNA methylation and genome organization 

      Scelfo, Andrea; Barra, Viviana; Abdennur, Nezar; Spracklin, George; Busato, Florence; e.a. (Rockefeller University Press, 2024-02-20)
      DNA methylation (DNAme) is a key epigenetic mark that regulates critical biological processes maintaining overall genome stability. Given its pleiotropic function, studies of DNAme dynamics are crucial, but currently ...