MIT Open Access Articles: Recent submissions
Now showing items 43-45 of 54555
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Co-evolution of alpha-helical transmembrane protein residues: large-scale variant profiling and complete mutational landscape of 2277 known PDB entries representing 504 unique human protein sequences
(Springer US, 2025-09-24)Membrane proteins play fundamental roles in cellular function, yet the evolutionary dynamics of their amino acid composition remain poorly understood. Our current study investigates the substitutional landscape and ... -
Perforation of the host cell plasma membrane during Toxoplasma invasion requires rhoptry exocytosis
(Nature Publishing Group UK, 2025-09-19)Toxoplasma gondii is an obligate intracellular parasite. Proteins released during host cell invasion from apical secretory organelles known as rhoptries are delivered into the host cell cytosol to perform functions critical ... -
Unknottedness of free boundary minimal surfaces and self-shrinkers
(Springer Berlin Heidelberg, 2025-09-08)We study unknottedness for free boundary minimal surfaces in a three-dimensional Riemannian manifold with nonnegative Ricci curvature and strictly convex boundary, and for self-shrinkers in the three-dimensional Euclidean ...
